A. Satterthwaite

发表

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

L. Davis, P. Lipsky, N. Olsen, 2013, PloS one.

The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.

A. Satterthwaite, L. Garrett-Sinha, Alyssa Kearly, 2016, Critical reviews in immunology.

Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.

A. Satterthwaite, D. Castrillon, T. Gallardo, 2009, International immunology.

B Cell Receptor Signaling Down-Regulates Forkhead Box Transcription Factor Class O 1 mRNA Expression via Phosphatidylinositol 3-Kinase and Bruton’s Tyrosine Kinase1

A. Satterthwaite, R. Hinman, Whitney A Nichols, 2007, The Journal of Immunology.

IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate

A. Satterthwaite, L. Garrett-Sinha, F. Brombacher, 2018, eLife.

Genetic analysis of tyrosine kinase function in B cell development.

A. Satterthwaite, O. Witte, Owen N. Witte, 1996, Annual review of immunology.

IL‐21 promotes the production of anti‐DNA IgG but is dispensable for kidney damage in lyn−/− mice

D. Rakheja, Quanzhen Li, A. Satterthwaite, 2013, European journal of immunology.

Structure of the gene encoding CD34, a human hematopoietic stem cell antigen.

M. L. Beau, D. Tenen, M. L. Le Beau, 1992, Genomics.

Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells.

D. Tenen, B. Seed, A. Satterthwaite, 1992, Journal of immunology.

Btk dosage determines sensitivity to B cell antigen receptor cross-linking.

A. Satterthwaite, O. Witte, W. Khan, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Btk function in B cell development and response.

A. Satterthwaite, O. Witte, Z. Li, 1998, Seminars in immunology.

Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase.

A. Satterthwaite, O. Witte, A. Chan, 2003, International immunology.

Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways

F. Alt, A. Satterthwaite, O. Witte, 1998, The Journal of experimental medicine.

Lessons from human genetic variants in the study of B-cell differentiation.

A. Satterthwaite, O. Witte, 1996, Current opinion in immunology.

Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia

M. Loh, T. Graeber, J. Coligan, 2015, Nature.

Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.

L. Davis, J. Hutcheson, Tianfu Wu, 2016, Clinical immunology.

Regulation of the Gene for CD 34 , a Human Hematopoietic Stem Cell Antigen , in KG1 Cells

D. Tenen, A. Satterthwaite, R. Borson, 2003 .

B Cell Receptor Signaling Down-Regulates Forkhead Box Transcription Factor Class O 1 mRNA Expression via Phosphatidylinositol 3-Kinase and Bruton’s Tyrosine Kinase

A. Satterthwaite, R. Hinman, Jessica N. Bushanam, 2006 .

Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels

Quanzhen Li, A. Satterthwaite, L. Garrett-Sinha, 2015, The Journal of Immunology.

Btk Plays a Crucial Role in the Amplification of FcϵRI-mediated Mast Cell Activation by Kit*

A. Satterthwaite, Shoko Iwaki, D. Metcalfe, 2005, Journal of Biological Chemistry.

Btk regulates multiple stages in the development and survival of B-1 cells.

A. Satterthwaite, R. Hinman, S. Clarke, 2007, Molecular immunology.

A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels

A. Satterthwaite, L. Garrett-Sinha, R. Rickert, 2014, The Journal of Immunology.

Reduced Dosage of Bruton’s Tyrosine Kinase Uncouples B Cell Hyperresponsiveness from Autoimmunity in lyn−/− Mice1

A. Satterthwaite, O. Witte, C. Lowell, 2003, The Journal of Immunology.

Complementary Roles for CD19 and Bruton’s Tyrosine Kinase in B Lymphocyte Signal Transduction1

M. Fujimoto, A. Satterthwaite, O. Witte, 2002, The Journal of Immunology.

IRF4 Has a Unique Role in Early B Cell Development and Acts Prior to CD21 Expression to Control Marginal Zone B Cell Numbers

A. Satterthwaite, K. Ottens, 2021, Frontiers in Immunology.

ActivationTyrosine Kinases, Btk and Lyn, in Mast Cell Redundant and Opposing Functions of Two

A. Satterthwaite, O. Witte, D. Rawlings, 2000 .

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

M. Loh, T. Graeber, J. Coligan, 2016 .

Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain.

A. Satterthwaite, O. Witte, K. Takatsu, 1995, Immunity.

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

J. Hutcheson, C. Mohan, A. Satterthwaite, 2012, Arthritis Research & Therapy.

TLR7 Signaling in Lupus B Cells: New Insights into Synergizing Factors and Downstream Signals

A. Satterthwaite, 2021, Current Rheumatology Reports.

Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn‐deficient mice

Quanzhen Li, A. Satterthwaite, Toni Gutierrez, 2010, European journal of immunology.

Autoreactive B Cell Responses to RNA-Related Antigens Due to TLR7 Gene Duplication

A. Satterthwaite, S. Bolland, M. Difilippantonio, 2006, Science.

The human CD34 hematopoietic stem cell antigen promoter and a 3' enhancer direct hematopoietic expression in tissue culture.

D. Tenen, A. Satterthwaite, T. Burn, 1992, Blood.

Constitutive membrane association potentiates activation of Bruton tyrosine kinase

A. Satterthwaite, O. Witte, D. Rawlings, 1997, Oncogene.

Btk and phospholipase Cγ2 can function independently during B cell development

A. Satterthwaite, R. Hinman, T. Coursey, 2007 .

Regulation of the gene for CD34, a human hematopoietic stem cell antigen, in KG-1 cells.

D. Tenen, A. Satterthwaite, R. Borson, 1990, Blood.

PIK3IP1 Promotes Extrafollicular Class Switching in T-Dependent Immune Responses

A. Satterthwaite, L. Kane, K. Ottens, 2020, The Journal of Immunology.

International System for Cytogenetic Nomenclature (ISCN) — guidelines on cancer cytogenetics

R. Eddy, T. Shows, M. Schmid, 1990 .

Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells.

A. Satterthwaite, Toni Gutierrez, Kristina E. Halcomb, 2008, Molecular immunology.

Btk in the Control of Antibody Levels Genetic Interaction between Lyn, Ets1, and

Quanzhen Li, A. Satterthwaite, L. Garrett-Sinha, 2015 .

A Btk transgene restores the antiviral TI‐2 antibody responses of xid mice in a dose‐dependent fashion

R. Zinkernagel, A. Satterthwaite, O. Witte, 1999, European journal of immunology.

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation.

A. Satterthwaite, Shoko Iwaki, L. Samelson, 2004, Blood.

aggregation ε leading to human mast cell degranulation following Kit activation and Fc NTAL phosphorylation is a pivotal link between the signaling cascades

A. Satterthwaite, Shoko Iwaki, L. Samelson, 2004 .

Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells.

R. Eddy, T. Shows, D. Tenen, 1990, Cytogenetics and cell genetics.

Multiple control elements are required for expression of the human CD34 gene.

D. Tenen, A. Satterthwaite, H. Radomska, 1999, Gene.

The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective.

A. Satterthwaite, O. Witte, Owen N. Witte, 2000, Immunological reviews.

B Cell Activation Results in IKK-Dependent, but Not c-Rel- or RelA-Dependent, Decreases in Transcription of the B Cell Tolerance-Inducing Gene Ets1.

A. Satterthwaite, L. Garrett-Sinha, Alyssa Kearly, 2022, ImmunoHorizons.

Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome.

A. Satterthwaite, O. Witte, J. Miller, 2001, Immunity.

Multiple control elements are required for expression of the human CD34 gene

D. Tenen, A. Satterthwaite, H. Radomska, 1998 .

Pathways leading to an immunological disease: systemic lupus erythematosus

L. Davis, A. Satterthwaite, A. Fairhurst, 2017, Rheumatology.

Genetics: Rare genes for autoimmunity—the new kids on the block

C. Mohan, A. Satterthwaite, 2010, Nature Reviews Rheumatology.

Impaired B Cell Apoptosis Results in Autoimmunity That Is Alleviated by Ablation of Btk

A. Satterthwaite, C. Bazile, Justin C. Boucher, 2021, Frontiers in Immunology.

Pathways leading to an immunological disease: systemic lupus erythematosus

L. Davis, A. Satterthwaite, A. Fairhurst, 2017, Rheumatology.

A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.

A. Tarakhovsky, H. Wu, L. Cantley, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.

L. Davis, Tianfu Wu, C. Mohan, 2007, The Journal of clinical investigation.

Redundant and Opposing Functions of Two Tyrosine Kinases, Btk and Lyn, in Mast Cell Activation1

A. Satterthwaite, O. Witte, D. Rawlings, 2000, The Journal of Immunology.

Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes

Amber C. Donahue, A. Satterthwaite, O. Witte, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Btk and phospholipase C gamma 2 can function independently during B cell development.

A. Satterthwaite, R. Hinman, T. Coursey, 2007, European journal of immunology.

A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene.

D. Tenen, A. Satterthwaite, H. Radomska, 1999, Blood.

Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus

Tianfu Wu, C. Mohan, A. Satterthwaite, 2016, PloS one.

Bruton’s Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus

A. Satterthwaite, 2018, Front. Immunol..

Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.

I. Weissman, K. Akashi, A. Satterthwaite, 2000, Proceedings of the National Academy of Sciences of the United States of America.

DSHP: a "power bar" for sustained immune responses?

A. Satterthwaite, O. Witte, D. Rawlings, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Foxo3 Promotes Apoptosis of B Cell Receptor–Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing

L. Davis, Quanzhen Li, A. Satterthwaite, 2018, The Journal of Immunology.

Recent Advances in Lupus B Cell Biology: PI3K, IFNγ, and Chromatin

A. Satterthwaite, Maria A. Bacalao, 2021, Frontiers in Immunology.

Xid-like phenotypes: a B cell signalosome takes shape.

A. Satterthwaite, O. Witte, D. Fruman, 2000, Immunity.

T‐bet‐expressing B cells contribute to the autoreactive plasma cell pool in Lyn‐/‐ mice

A. Satterthwaite, K. Ottens, Jalyn Schneider, 2023, European journal of immunology.