Eric Shifrut

发表

T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity

N. Friedman, S. Reich-Zeliger, I. Cohen, 2014, Genome research.

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

N. Friedman, S. Reich-Zeliger, I. Cohen, 2017, eLife.

Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization

J. Shawe-Taylor, N. Friedman, S. Reich-Zeliger, 2017, Front. Immunol..

Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells

A. May, N. Krogan, David Tse, 2019, Nature Biotechnology.

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

A. Ashworth, A. Marson, Eric Shifrut, 2018, Cell.

Mapping gene regulatory networks of primary CD4+ T cells using single-cell genomics and genome engineering

Chun Jimmie Ye, A. Marson, Meena Subramaniam, 2019, bioRxiv.

Chromatin conformation governs T-cell receptor Jβ gene segment usage

Wilfred Ndifon, Nir Friedman, Hilah Gal, 2012, Proceedings of the National Academy of Sciences.

Correction of autoimmune IL2RA mutations in primary human T cells using non-viral genome targeting

Channabasavaiah B. Gurumurthy, Rolen M. Quadros, A. May, 2017 .

Reprogramming human T cell function and specificity with non-viral genome targeting

Channabasavaiah B. Gurumurthy, Rolen M. Quadros, A. Ashworth, 2017, bioRxiv.

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Ansuman T. Satpathy, A. Ashworth, A. Marson, 2022, bioRxiv.

Dynamic response diversity of NFAT isoforms in individual living cells.

Nir Friedman, Ziv Porat, Eric Shifrut, 2013, Molecular cell.

Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

N. Friedman, A. Sali, P. Paz, 2018, bioRxiv.

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

N. Friedman, M. Mattson, M. Schwartz, 2013, Proceedings of the National Academy of Sciences.

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Ansuman T. Satpathy, A. Marson, Eric Shifrut, 2022, Nature.

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Jonathan H. Esensten, A. Marson, Eric Shifrut, 2022, Nature Biotechnology.

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Chun Jimmie Ye, C. T. Mowery, Daniel B. Goodman, 2022, Cell.

A Cas9 nanoparticle system with truncated Cas9 target sequences on DNA repair templates enhances genome targeting in diverse human immune cell types

Daniel B. Goodman, J. Puck, J. Bluestone, 2019, bioRxiv.

memento: Generalized differential expression analysis of single-cell RNA-seq with method of moments estimation and efficient resampling

Chun Jimmie Ye, A. Marson, Rachel E. Gate, 2022, bioRxiv.

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Daniel B. Goodman, J. Puck, J. Bluestone, 2019, Nature Biotechnology.

Reprogramming human T cell function and specificity with non-viral genome targeting

A. Ashworth, A. May, J. Weissman, 2017, bioRxiv.

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Hunter M Nisonoff, Chun Jimmie Ye, Hunter M. Nisonoff, 2021, Science Advances.

Layilin augments integrin activation to promote antitumor immunity

Jacob M. Luber, A. Marson, Eric Shifrut, 2020, The Journal of experimental medicine.

A functional map of HIV-host interactions in primary human T cells

Ryan T. Leenay, N. Krogan, Janet M. Young, 2022, Nature Communications.

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Kole T. Roybal, Daniel B. Goodman, J. Bluestone, 2019, bioRxiv.

Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression

A. Ashworth, A. Marson, Eric Shifrut, 2022, Molecular & cellular proteomics : MCP.

Hypoxia is a dominant remodeler of the CD8+ T cell surface proteome relative to activation and regulatory T cell-mediated suppression

A. Ashworth, A. Marson, Eric Shifrut, 2021, bioRxiv.

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

John Shawe-Taylor, Nir Friedman, Niclas Thomas, 2014, bioRxiv.

McPAS‐TCR: a manually curated catalogue of pathology‐associated T cell receptor sequences

Jaime Prilusky, Nir Friedman, Nili Tickotsky, 2017, Bioinform..

CRISPR Screen in Regulatory T Cells Reveals Modulators of Foxp3

J. Bluestone, A. Marson, Eric Shifrut, 2020, Nature.

Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity.

N. Friedman, S. Reich-Zeliger, Steffen Jung, 2015, Immunity.

Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire

Nir Friedman, Eric Shifrut, Peter D Sun, 2019, Nature Communications.

Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells

A. May, N. Krogan, David Tse, 2019, Nature Biotechnology.

Reprogramming human T cell function and specificity with non-viral genome targeting

J. Weissman, M. Leonetti, S. Hughes, 2018, Nature.

Monitoring the dynamics of primary T cell activation and differentiation using long term live cell imaging in microwell arrays.

Nir Friedman, Guy Aidelberg, Eric Shifrut, 2012, Lab on a chip.

CRISPR Screen in Regulatory T Cells Reveals Ubiquitination Modulators of Foxp3

J. Bluestone, A. Marson, Eric Shifrut, 2020, bioRxiv.

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

Chun Jimmie Ye, S. Targ, J. Bluestone, 2020, Nature Immunology.

CD4+ T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions

Wilfred Ndifon, Nir Friedman, Hilah Gal, 2013, Front. Immunol..

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

Chun Jimmie Ye, S. Targ, J. Bluestone, 2020, Nature Immunology.

Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire

N. Friedman, Marco Craveiro, Eric Shifrut, 2019, Nature Communications.

Reprogramming human T cell function and specificity with non-viral genome targeting

Jonathan S. Weissman, Alan Ashworth, Antoni Ribas, 2017, Nature.

Tracking global changes induced in the CD4 T cell receptor repertoire by immunisation with a complex antigen using local sequence features of CDR3 protein sequence

John Shawe-Taylor, Nir Friedman, Niclas Thomas, 2014 .

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence.

Ansuman T. Satpathy, A. Ashworth, A. Marson, 2022, Cancer cell.

Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

N. Friedman, A. Sali, P. Paz, 2018, bioRxiv.