B. de Crombrugghe

发表

Cyclic AMP receptor protein: role in transcription activation.

H. Buc, B. de Crombrugghe, S. Busby, 1984, Science.

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation.

S. Murakami, B. de Crombrugghe, Ren Zhang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis.

B. de Crombrugghe, C. V. Van Pelt, D. Abraham, 2010, Arthritis and rheumatism.

Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest

D. Rowitch, B. de Crombrugghe, H. Akiyama, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells

B. de Crombrugghe, G. Lozano, S. Xiong, 2021, Cell Death & Disease.

Determination of the nucleotide sequence of part of the regulatory region for the galactose operon from Escherichia coli.

S. Weissman, J. Sklar, B. de Crombrugghe, 1977, The Journal of biological chemistry.

Genetic evidence for the vital function of osterix in cementogenesis

B. de Crombrugghe, Jian Q. Feng, M. Somerman, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Three High Mobility Group-like Sequences within a 48-Base Pair Enhancer of the Col2a1 Gene Are Required for Cartilage-specific Expression in Vivo *

V. Lefebvre, G. Zhou, B. de Crombrugghe, 1998, The Journal of Biological Chemistry.

A Gene for a Novel Zinc-finger Protein Expressed in Differentiated Epithelial Cells and Transiently in Certain Mesenchymal Cells*

Michael F. Seldin, M. Seldin, B. de Crombrugghe, 1996, The Journal of Biological Chemistry.

Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes.

B. de Crombrugghe, B. Crombrugghe, X. Zhou, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for three major transcription activation elements in the proximal mouse proalpha2(I) collagen promoter.

B. de Crombrugghe, X. Zhou, E. Ruteshouser, 1996, Nucleic acids research.

A New Long Form of c-Maf Cooperates with Sox9 to Activate the Type II Collagen Gene*

B. de Crombrugghe, Wendong Huang, H. Eberspaecher, 2002, The Journal of Biological Chemistry.

ATPase activity required for termination of transcription by the Escherichia coli protein factor rho.

B. de Crombrugghe, B. Howard, B. De Crombrugghe, 1976, The Journal of biological chemistry.

Isolation of genomic DNA clones spanning the entire fibronectin gene.

I. Pastan, B. de Crombrugghe, K. Yamada, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts.

I. Pastan, B. de Crombrugghe, B. Howard, 1977, Proceedings of the National Academy of Sciences of the United States of America.

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

P N Goodfellow, P. Goodfellow, V. Lefebvre, 1997, Molecular and cellular biology.

A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6*

B. de Crombrugghe, H. Yasuda, Di Chen, 2016, The Journal of Biological Chemistry.

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc

B. de Crombrugghe, H. Yasuda, Di Chen, 2015, Scientific Reports.

E6-AP/UBE3A Protein Acts as a Ubiquitin Ligase toward SOX9 Protein*

B. de Crombrugghe, H. Yasuda, M. Takigawa, 2013, The Journal of Biological Chemistry.

The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template

B. de Crombrugghe, H. Yasuda, F. Coustry, 2010, Nucleic acids research.

FGF signaling antagonizes cytokine-mediated repression of Sox9 in SW1353 chondrosarcoma cells.

B. de Crombrugghe, L. Buckbinder, J. Schaefer, 2003, Osteoarthritis and cartilage.

Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements.

B. de Crombrugghe, L. Bridgewater, T. Ellison, 2003, Nucleic acids research.

Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors.

B. Czerniak, B. de Crombrugghe, Wendong Huang, 2003, Human pathology.

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway.

S. Murakami, B. de Crombrugghe, M. Kan, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of MicroRNAs Controlled by the Osteoblast-Specific Transcription Factor Osterix

Wenbin Liu, B. de Crombrugghe, H. Yasuda, 2013, PloS one.

Deletion analysis of the mouse alpha 1(III) collagen promoter.

B. de Crombrugghe, M. Mudryj, B. De Crombrugghe, 1988, Nucleic acids research.

Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells.

B. de Crombrugghe, K. Hirschi, H. Chao, 2014, Cell reports.

Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure.

B. de Crombrugghe, N. Bhowmick, J. Davidson, 2010, The American journal of pathology.

The family of collagen genes.

E. Vuorio, B. de Crombrugghe, B. De Crombrugghe, 1990, Annual review of biochemistry.

Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts.

B. de Crombrugghe, J. Rossert, H. Eberspaecher, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and Characterization of a Transcription Factor That Binds to the Proximal Promoters of the Two Mouse Type I Collagen Genes*

B. de Crombrugghe, O. Miyaishi, A. Takeuchi, 1997, The Journal of Biological Chemistry.

Transcriptional suppression of cellular gene expression by c-Myc

B. de Crombrugghe, B. S. Yang, S. Freytag, 1991, Molecular and cellular biology.

Positive Regulation of Adult Bone Formation by Osteoblast‐Specific Transcription Factor Osterix

B. de Crombrugghe, Shin-Yoon Kim, H. Akiyama, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene.

E. Vuorio, B. de Crombrugghe, H. Salminen, 2000, Osteoarthritis and cartilage.

The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern.

E. Vuorio, B. de Crombrugghe, I. Eerola, 1993, The Biochemical journal.

TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation

B. de Crombrugghe, M. Mattei, Xin Zhou, 1993, Molecular and cellular biology.

Phosphorylation of SOX9 by Cyclic AMP-Dependent Protein Kinase A Enhances SOX9's Ability To Transactivate aCol2a1 Chondrocyte-Specific Enhancer

V. Lefebvre, B. de Crombrugghe, Wendong Huang, 2000, Molecular and Cellular Biology.

Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth.

B. de Crombrugghe, Jung-Eun Kim, K. Nakashima, 2004, The American journal of pathology.

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs.

E. Vuorio, B. de Crombrugghe, M. Metsäranta, 1991, Biochimica et biophysica acta.

Construction of a recombinant bacterial plasmid containing a chick pro-alpha2 collagen gene sequence.

I. Pastan, B. de Crombrugghe, T. Yamamoto, 1978, Proceedings of the National Academy of Sciences of the United States of America.

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

B. de Crombrugghe, M. Taketo, G. Schett, 2012, Annals of the Rheumatic Diseases.

Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx.

B. de Crombrugghe, Chi Zhang, H. Dai, 2012, Biochemical and biophysical research communications.

The postnatal role of Sox9 in cartilage

B. de Crombrugghe, S. Liang, K. Akdemir, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sclerostin is a direct target of osteoblast-specific transcription factor osterix.

B. de Crombrugghe, Chi Zhang, Wanjin Tang, 2010, Biochemical and biophysical research communications.

Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix

Kyucheol Cho, P. McCrea, B. de Crombrugghe, 2008, Proceedings of the National Academy of Sciences.

Enhanced type III collagen gene expression during bleomycin induced lung fibrosis.

B. de Crombrugghe, R. McAnulty, P. Jeffery, 1993, Thorax.

Downregulation of rheumatoid arthritis‐related antigen RA‐A47 (HSP47/colligin‐2) in chondrocytic cell lines induces apoptosis and cell‐surface expression of RA‐A47 in association with CD9

B. de Crombrugghe, M. Takigawa, S. Kubota, 2005, Journal of cellular physiology.

Attenuation of fibrosis in vitro and in vivo with SPARC siRNA

F. Arnett, B. de Crombrugghe, Xiaodong Zhou, 2010, Arthritis research & therapy.

Interferon alfa down‐regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice

H. Yamauchi, B. de Crombrugghe, Y. Inagaki, 2003, Hepatology.

Two different negative and one positive regulatory factors interact with a short promoter segment of the alpha 1 (I) collagen gene.

B. de Crombrugghe, G. Karsenty, B. De Crombrugghe, 1990, The Journal of biological chemistry.

Molecular cloning and characterization of a novel rat activin receptor.

B. de Crombrugghe, R. Legerski, P. Segarini, 1992, Biochemical and biophysical research communications.

Purification of a novel factor which binds to the mouse α2 (I) collagen promoter

B. de Crombrugghe, T. Krieg, A. Hatamochi, 1993 .

Interactions between Sox9 and beta-catenin control chondrocyte differentiation.

P. McCrea, J. Deng, R. Behringer, 2004, Genes & development.

Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.

R. Behringer, B. de Crombrugghe, C. Denton, 2007, Arthritis and rheumatism.

Osterix Regulates Tooth Root Formation in a Site-specific Manner

B. de Crombrugghe, E. Cho, C. Bae, 2015, Journal of dental research.

Persistent Low Level of Osterix Accelerates Interleukin-6 Production and Impairs Regeneration after Tissue Injury

B. de Crombrugghe, Seung-Yoon Park, K. Park, 2013, PloS one.

The properties of thyroglobulin. 13. The structure of reduced alkylated thyroglobulin.

B. de Crombrugghe, H. Edelhoch, 1966, The Journal of biological chemistry.

Osterix is required for cranial neural crest-derived craniofacial bone formation.

B. de Crombrugghe, Jung-Eun Kim, W. Baek, 2013, Biochemical and biophysical research communications.

Sp7 and Runx2 molecular complex synergistically regulate expression of target genes

Hengbin Wang, B. de Crombrugghe, A. Javed, 2014, Connective tissue research.

Regulation or procollagen messenger ribonucleic acid levels in Rous sarcoma virus transformed chick embryo fibroblasts.

I. Pastan, B. de Crombrugghe, T. Yamamoto, 1981, Biochemistry.

Aging and cancer: cyclic 3', 5'-adenosine monophosphate and altered gene activity.

I. Pastan, M. Willingham, M. Gottesman, 1982, National Cancer Institute monograph.

Accurate in vitro transcriptional initiation of the chick alpha 2 (Type I) collagen gene.

I. Pastan, B. de Crombrugghe, G. Merlino, 1981, The Journal of biological chemistry.

Structure of the promoter for chicken alpha 2 type I collagen gene.

I. Pastan, B. de Crombrugghe, Y. Yamada, 1981, Proceedings of the National Academy of Sciences of the United States of America.

B. de Crombrugghe, J. Rossert, H. Eberspaecher, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional Mechanisms Controlling Types I and III Collagen Genes

B. de Crombrugghe, G. Karsenty, P. Rossi, 1990, Annals of the New York Academy of Sciences.

A new long form of Sox5 (L‐Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Véronique Lefebvre, Ping Li, V. Lefebvre, 1998, The EMBO journal.

Attenuation of Expression of Extracellular Matrix Genes with siRNAs to SPARC and CTGF in Skin Fibroblasts of CTGF Transgenic Mice

F. Arnett, B. de Crombrugghe, B. Crombrugghe, 2011, International journal of immunopathology and pharmacology.

Transforming growth factor‐β isoforms differently stimulate proα2 (I) collagen gene expression during wound healing process in transgenic mice

B. de Crombrugghe, Y. Inagaki, K. Takehara, 2002 .