B. Briney

发表

Commonality despite exceptional diversity in the baseline human antibody repertoire

D. Burton, B. Briney, Anne Inderbitzin, 2018, Nature.

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.

Bryan Briney, Ian A Wilson, Dennis R Burton, 2016, Cell reports.

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Joseph G. Jardine, Oleksandr Kalyuzhniy, Yumiko Adachi, 2016, Science.

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

Daphne Koller, George M. Church, Jonathan Laserson, 2013, PLoS pathogens.

Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

James E. Crowe, Jordan R. Willis, J. Crowe, 2012, PloS one.

Secondary mechanisms of diversification in the human antibody repertoire

B. Briney, Bryan S. Briney, James E. Crowe Jr., 2013, Front. Immunol..

Broadening a SARS-CoV-1 neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

D. Burton, I. Wilson, B. Briney, 2021, bioRxiv.

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Timothy A. Whitehead, D. Burton, C. T. Brown, 2015, bioRxiv.

Efficient isolation of rare B cells using next-generation antigen barcoding

W. Schief, B. Briney, Eugenia C Salcedo, 2022, bioRxiv.

Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults

Erin E. Gill, R. Scheuermann, D. Burton, 2020, Frontiers in Immunology.

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

D. Burton, D. Watkins, R. Desrosiers, 2017, Science Translational Medicine.

Overline : Emerging infections One Sentence Summary : Neutralizing antibodies prevent Zika infection

D. Burton, D. Watkins, R. Desrosiers, 2022 .

Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies

B. Briney, R. Sanders, G. Boons, 2022, bioRxiv.

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

D. Burton, B. Briney, D. Nemazee, 2020, bioRxiv.

Advancing computational biology and bioinformatics research through open innovation competitions

Karim R. Lakhani, Andrew I. Su, Chunlei Wu, 2019, bioRxiv.

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2017, Immunity.

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

Yana Safonova, D. Irvine, D. Burton, 2021, bioRxiv.

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

D. Burton, I. Wilson, B. Briney, 2020, Science.

AntiRef: reference clusters of human antibody sequences

B. Briney, Bryan S. Briney, 2022, bioRxiv.

Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences

Mikhail Shugay, Victor Greiff, Enkelejda Miho, 2019, Bioinform..

Massively scalable genetic analysis of antibody repertoires

Dennis R. Burton, Bryan Briney, D. Burton, 2018, bioRxiv.

Tissue-Specific Expressed Antibody Variable Gene Repertoires

Brett A. McKinney, James E. Crowe, Jordan R. Willis, 2014, PloS one.

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

Jordan R. Willis, J. Crowe, B. Briney, 2012, Immunology.

Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence

James E Crowe, J. Crowe, B. Briney, 2011, The Journal of Immunology.

ConvergenceSequence Divergence and Interclonal Repertoires Diversify by B Cell Intraclonal Epitope-Specific Human Influenza Antibody

J. Crowe, B. Briney, Jens C. Krause, 2011 .

Viral immunity: Basic mechanisms and therapeutic applications—a Keystone Symposia report

P. Bjorkman, G. Nabel, K. Kedzierska, 2023, Annals of the New York Academy of Sciences.

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

Dennis R. Burton, Bryan Briney, D. Burton, 2016, Scientific Reports.

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

Ben Murrell, William R. Schief, Thomas Vollbrecht, 2019, Immunity.

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2016, Cell.

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

Pseudovirion Particles Bearing Native HIV Envelope Trimers Facilitate a Novel Method for Generating Human Neutralizing Monoclonal Antibodies Against HIV

S. Kalams, J. Crowe, B. Briney, 2010, Journal of acquired immune deficiency syndromes.

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

John P. Moore, D. Burton, B. Briney, 2014, Proceedings of the National Academy of Sciences.

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies

Samuel L. DeLuca, Jens Meiler, James E. Crowe, 2013, PLoS Comput. Biol..

High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals

B A McKinney, Jordan R. Willis, B. McKinney, 2012, Genes and Immunity.

Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity

James E. Crowe, Jordan R. Willis, J. Crowe, 2012, Genes and Immunity.

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Dong Soo Yun, Daniel W. Kulp, D. Irvine, 2016, Immunity.

Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

D. Burton, B. Briney, Collin Joyce, 2019, Scientific Reports.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

Daniel W. Kulp, Jordan R. Willis, Xiaozhen Hu, 2019, Science.

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization

D. Irvine, D. Burton, W. Schief, 2019, Cell reports.

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2016, Immunity.

Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization

D. Montefiori, J. Meiler, J. Crowe, 2016, Proceedings of the National Academy of Sciences.

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design.

D. Burton, Chi‐Huey Wong, B. Briney, 2015, Immunity.

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2015, Science.

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Daniel W. Kulp, D. Burton, A. Bradley, 2016, Science.

Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors

Bryan Briney, Nathan Beutler, Dennis R Burton, 2017, Science Immunology.

Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease

Lisa E. Gralinski, Yana Safonova, D. Burton, 2023, Immunity.

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development.

D. Burton, Chi‐Huey Wong, B. Briney, 2017, Immunity.

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

D. Burton, I. Wilson, Chi‐Huey Wong, 2016, Immunity.

Glycans Function as Ancho rs for Antibodies andHelp Drive HIV Broadly Neutralizing Antibody Development Graphical

D. Burton, Chi‐Huey Wong, B. Briney, 2017 .

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

D. Burton, B. Briney, Collin Joyce, 2020, Cell reports.

Longitudinally Tracked, Rapid and Robust Antigen-Specific Germinal Center Responses in Non-Human Primates after a Single Nanoparticle Vaccine Immunization

D. Irvine, D. Burton, W. Schief, 2019, SSRN Electronic Journal.

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.

Jennifer S. Wood, B. Pulendran, John P. Moore, 2016, Cell reports.

Reprogramming the antigen specificity of B cells using genome-editing technologies

David Nemazee, Ben Murrell, Bryan Briney, 2018, bioRxiv.

Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes

D. Jaffe, D. Burton, M. Stubbington, 2023, bioRxiv.

Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein

Jordan R. Willis, S. Kalams, J. Crowe, 2016, PloS one.

Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV

William R. Schief, Michael S. Seaman, Dennis R. Burton, 2014, Science Translational Medicine.

Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies

D. Burton, B. Briney, Collin Joyce, 2023, PLoS pathogens.

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development.

D. Burton, Chi‐Huey Wong, B. Briney, 2017, Immunity.

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypes

S. Kabra, D. Burton, B. Briney, 2023, bioRxiv.

Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift

Yana Safonova, D. Burton, B. Briney, 2023, bioRxiv.

B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypes

S. Kabra, D. Burton, B. Briney, 2023, bioRxiv.

Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization

Jordan R. Willis, D. Montefiori, J. Meiler, 2016, Proceedings of the National Academy of Sciences.