J. Dimitrov

S. Kaveri, J. Dimitrov, J. Bayry, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Potential Predictive Role of Lipid Peroxidation Markers for Type 2 Diabetes in the Adult Tunisian Population.

S. Kaveri, J. Dimitrov, Rania Abdelhedi, 2017, Canadian journal of diabetes.

How can polyreactive antibodies conquer rapidly evolving viruses?

J. Dimitrov, Alejandra Reyes-Ruiz, 2021, Trends in immunology.

Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers

M. Ait-goughoulte, J. Dimitrov, S. Pol, 2020, The Journal of experimental medicine.

Thermodynamic stability contributes to immunoglobulin specificity.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2014, Trends in biochemical sciences.

Stimulation with FITC-labeled antigens confers B cells with regulatory properties.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2020, Cellular immunology.

Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2018, Cellular immunology.

Evolutionary trajectory of the physicochemical mechanism of interaction of SARS-CoV-2 spike protein with ACE2

B. Atanasov, M. Lecerf, J. Dimitrov, 2022 .

A human FVIII inhibitor modulates FVIII surface electrostatics at a VWF‐binding site distant from its epitope

B. Atanasov, S. Kaveri, S. Lacroix-Desmazes, 2010, Journal of thrombosis and haemostasis : JTH.

Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance

D. Scott, N. Gupta, S. Justesen, 2015, Science Translational Medicine.

A Cellular Viewpoint of Anti-FVIII Immune Response in Hemophilia A

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2009, Clinical reviews in allergy & immunology.

Natural Antibodies: from First-Line Defense Against Pathogens to Perpetual Immune Homeostasis

S. Kaveri, S. Lacroix-Desmazes, M. Kazatchkine, 2019, Clinical Reviews in Allergy & Immunology.

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2013, Haematologica.

V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor

S. Justesen, M. Lecerf, J. Dimitrov, 2020, The Journal of Immunology.

TCR Stimulation Drives Cleavage and Shedding of the ITIM Receptor CD31

J. Dimitrov, M. Clément, G. Caligiuri, 2010, The Journal of Immunology.

Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE.

S. Kaveri, J. Dimitrov, P. Bruhns, 2019, The Journal of allergy and clinical immunology.

Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin

S. Kaveri, J. Dimitrov, V. Sharma, 2016, Scientific Reports.

Induction of heme oxygenase-1 in factor VIII-deficient mice reduces the immune response to therapeutic factor VIII.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2010, Blood.

Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis

S. Miescher, P. Houillier, J. Dimitrov, 2018, Front. Immunol..

Intravenous immunoglobulins exposed to heme (heme IVIG) are more efficient than IVIG in attenuating autoimmune diabetes.

J. Dimitrov, N. Arsenijević, M. Lukic, 2011, Clinical immunology.

TCR Stimulation Drives Cleavage and Shedding of the ITIM Receptor CD31

J. Dimitrov, M. Clément, G. Caligiuri, 2010, The Journal of Immunology.

Optimization of casein-based semisynthetic medium for growing of toxigenic Corinebacterium diphtheriae in a fermenter.

J. Dimitrov, A. Tchorbanov, T. Vassilev, 2004, Canadian journal of microbiology.

Molecular composition of diphtheria toxoid produced using semi-synthetic and meat extract-based broths

J. Dimitrov, A. Tchorbanov, T. Vassilev, 2004 .

Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.

S. Miescher, P. Houillier, J. Dimitrov, 2018, JCI insight.

Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

P. Nilsson, K. Ekdahl, J. Dimitrov, 2022, Frontiers in Immunology.

Longitudinal and Integrative Biomodeling of Effector and Memory Immune Compartments after Inactivated Influenza Vaccination

A. Samri, C. Katlama, F. Carrat, 2013, The Journal of Immunology.

VaccinationCompartments after Inactivated Influenza Effector and Memory Immune Longitudinal and Integrative Biomodeling of

Malka, A. Samri, C. Katlama, 2013 .

Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis*

J. Dimitrov, V. Frémeaux-Bacchi, Rémi Noé, 2015, The Journal of Biological Chemistry.

Assessment of the breadth of binding promiscuity of heme towards human proteins

J. Dimitrov, L. Roumenina, 2022, Biological chemistry.

Heme Interacts with C1q and Inhibits the Classical Complement Pathway*

B. Atanasov, S. Kaveri, S. Lacroix-Desmazes, 2011, The Journal of Biological Chemistry.

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2

B. Atanasov, M. Lecerf, J. Dimitrov, 2022, bioRxiv.

Bortezomib delays the onset of factor VIII inhibitors in experimental hemophilia A, but fails to eliminate established anti‐factor VIII IgG‐producing cells

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2011, Journal of thrombosis and haemostasis : JTH.

Methods for Assessment of Interactions of Proteins with Heme: Application for Complement Proteins and Immunoglobulins.

J. Dimitrov, Margot Revel, 2021, Methods in molecular biology.

Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2

S. Watson, J. Dimitrov, Y. Di, 2020, Haematologica.

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner

J. Dimitrov, V. Frémeaux-Bacchi, N. Merle, 2019, Proceedings of the National Academy of Sciences.

Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1

J. Dimitrov, S. Satchell, P. Mathieson, 2018, Front. Immunol..

Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1

J. Dimitrov, S. Satchell, P. Mathieson, 2018 .

Proteolytic antibodies activate factor IX in patients with acquired hemophilia.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2011, Blood.

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome.

J. Dimitrov, V. Frémeaux-Bacchi, L. Halbwachs‐Mecarelli, 2013, Blood.

hemolytic uremic syndrome Complement activation by heme as a secondary hit for atypical

J. Dimitrov, V. Frémeaux-Bacchi, L. Halbwachs‐Mecarelli, 2013 .

Inhibitors of factor VIII in hemophilia.

S. Lacroix-Desmazes, J. Dimitrov, Y. Repesse, 2009, The New England journal of medicine.

Noncanonical antibody strategy for broad and potent neutralization of influenza virus

J. Dimitrov, 2021, Cellular & Molecular Immunology.

Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum.

S. Lacroix-Desmazes, M. Lecerf, J. Dimitrov, 2019, Journal of pharmaceutical and biomedical analysis.

Haemarthrosis and arthropathy do not favour the development of factor VIII inhibitors in severe haemophilia A mice

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2015, Haemophilia : the official journal of the World Federation of Hemophilia.

Factor VIII‐hydrolyzing IgG in acquired and congenital hemophilia

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2009, FEBS letters.

Predictive immunogenicity of Refacto® AF

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Dendritic Cells in Autoimmune Diseases

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2010 .

Heme binds to factor VIII and inhibits its interaction with activated factor IX

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2012, Journal of thrombosis and haemostasis : JTH.

Antibody polyspecificity: what does it matter?

J. Dimitrov, A. Pashov, T. Vassilev, 2012, Advances in experimental medicine and biology.

Iron Ions and Haeme Modulate the Binding Properties of Complement Subcomponent C1q and of Immunoglobulins

J. Dimitrov, T. Vassilev, L. Roumenina, 2007, Scandinavian journal of immunology.

of Birmingham Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2

S. Watson, J. Dimitrov, L. Roumenina, 2020 .

Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2012, Biochemistry.

Anti-IgE IgG autoantibodies isolated from therapeutic normal IgG intravenous immunoglobulin induce basophil activation

S. Kaveri, J. Dimitrov, J. Bayry, 2019, Cellular & Molecular Immunology.

Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2

F. Rey, J. Dimitrov, F. Agou, 2022, bioRxiv.

The receptor for advanced glycation end products is a sensor for cell‐free heme

S. Lancel, J. Dimitrov, M. Billamboz, 2020, The FEBS journal.

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity

J. Dimitrov, H. Mouquet, O. Schwartz, 2018, Cell reports.

Interaction with 2,4-dinitrophenol correlates with polyreactivity, self-binding, and stability of clinical-stage therapeutic antibodies.

M. Lecerf, J. Dimitrov, Rémi Noé, 2021, Molecular immunology.

Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities

M. Lecerf, Alexia Kanyavuz, J. Dimitrov, 2021, Communications Biology.

Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity*

C. Berek, S. Kaveri, S. Lacroix-Desmazes, 2015, The Journal of Biological Chemistry.

Method for identification of heme-binding proteins and quantification of their interactions

M. Lecerf, Alexia Kanyavuz, J. Dimitrov, 2019, bioRxiv.

Breaking the law: unconventional strategies for antibody diversification

S. Lacroix-Desmazes, Alexia Kanyavuz, J. Dimitrov, 2019, Nature Reviews Immunology.

A Cryptic Polyreactive Antibody Recognizes Distinct Clades of HIV-1 Glycoprotein 120 by an Identical Binding Mechanism*

C. Berek, S. Kaveri, S. Lacroix-Desmazes, 2014, The Journal of Biological Chemistry.

Antibodies Use Heme as a Cofactor to Extend Their Pathogen Elimination Activity and to Acquire New Effector Functions*

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2007, Journal of Biological Chemistry.

Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils

David F. Smith, R. Cummings, J. Dimitrov, 2020, Frontiers in Immunology.

Development of Inhibitory Antibodies to Therapeutic Factor VIII in Severe Hemophilia A Is Associated with Microsatellite Polymorphism in the HMOX1 promoter

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2012 .

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

B. Walker, F. Rey, J. Dimitrov, 2022, The Journal of experimental medicine.

Molecular basis for bacterial peptidoglycan recognition by LysM domains

S. Foster, S. Lacroix-Desmazes, J. Dimitrov, 2014, Nature Communications.

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance

S. Kaveri, S. Lacroix-Desmazes, M. Lecerf, 2020, Frontiers in Immunology.

syndrome endothelial cells and contributes to atypical hemolytic uremic Hyperfunctional C3 convertase leads to complement deposition on

C. Sautès-Fridman, W. Fridman, J. Dimitrov, 2014 .

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome.

C. Sautès-Fridman, W. Fridman, J. Dimitrov, 2009, Blood.

Hyperfunctional C 3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome

C. Sautès-Fridman, W. Fridman, J. Dimitrov, 2009 .

Mechanism and functional implications of the heme-induced binding promiscuity of IgE.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2015, Biochemistry.

Heterogeneous antigen recognition behavior of induced polyspecific antibodies.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2010, Biochemical and biophysical research communications.

Auditing Protein Therapeutics Management by Professional APCs: Toward Prevention of Immune Responses against Therapeutic Proteins1

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2008, The Journal of Immunology.

Noncanonical Functions of Antibodies.

S. Lacroix-Desmazes, J. Dimitrov, 2020, Trends in immunology.

Hydrolysis of Coagulation Factors by Circulating IgG Is Associated with a Reduced Risk for Chronic Allograft Nephropathy in Renal Transplanted Patients1

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2008, The Journal of Immunology.

Renal Transplanted Patients Risk for Chronic Allograft Nephropathy in Reduced Circulating IgG Is Associated with a Hydrolysis of Coagulation Factors by

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2008 .

Hypomagnesemia, Hypocalcemia, and Tubulointerstitial Nephropathy Caused by Claudin-16 Autoantibodies

P. Houillier, J. Dimitrov, L. Cheval, 2022, Journal of the American Society of Nephrology : JASN.

Identification of target antigens of self‐reactive IgG in intravenous immunoglobulin preparations

S. Kaveri, J. Dimitrov, L. Mouthon, 2009, Proteomics.

Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme

S. Kaveri, M. Lecerf, J. Dimitrov, 2019, Molecular immunology.

Antibody Polyreactivity in Health and Disease: Statu Variabilis

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2013, Journal of Immunology.

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

H. Wardemann, Alexia Kanyavuz, J. Dimitrov, 2019, Cell reports.

Antibody-mediated catalysis: induction and therapeutic relevance.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2013, Autoimmunity reviews.

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

N. Gupta, S. Justesen, S. Buus, 2015, Diabetes.

Relationship between natural and heme-mediated antibody polyreactivity.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2016, Biochemical and biophysical research communications.

Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

S. Justesen, S. Lacroix-Desmazes, M. Lecerf, 2023, International journal of molecular sciences.

Conservative pattern of interaction of bat and human IgG antibodies with FcRn.

S. Justesen, J. Dimitrov, Nia Toshkova, 2022, Developmental and comparative immunology.

Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

S. Kaveri, S. Lacroix-Desmazes, M. Lecerf, 2023, Communications Biology.

Evaluation of Binding Kinetics and Thermodynamics of Antibody-Antigen Interactions and Interactions Involving Complement Proteins.

J. Dimitrov, S. Rossini, 2021, Methods in molecular biology.

Heme-Exposed Pooled Therapeutic IgG Improves Endotoxemia Survival

J. Dimitrov, T. Stefanova, T. Vassilev, 2017, Inflammation.

Thermodynamic Analysis of Antibody–Antigen Interactions

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2012 .

Kinetics and thermodynamics of interaction of coagulation factor VIII with a pathogenic human antibody.

B. Atanasov, S. Kaveri, S. Lacroix-Desmazes, 2009, Molecular immunology.

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2017, Scientific Reports.

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.

J. Dimitrov, H. Mouquet, M. Vos, 2023, Cell host & microbe.

Immature and mature antibodies as defenders against cancer

J. Dimitrov, S. Sibéril, Robin Lacombe, 2022, Cellular & Molecular Immunology.

ATVB IN FOCUS: Thromboinflammation and Infection

J. Dimitrov, K. Suzuki-Inoue, L. Roumenina, 2023 .

Functional Changes of Therapeutic Antibodies upon Exposure to Pro-Oxidative Agents

M. Lecerf, Alexia Kanyavuz, J. Dimitrov, 2022, Antibodies.

Heme: driver of erythrocyte elimination.

J. Dimitrov, L. Roumenina, 2021, Blood.

Method for identification of heme-binding proteins and quantification of their interactions.

M. Lecerf, Alexia Kanyavuz, J. Dimitrov, 2020, Analytical biochemistry.

Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity

M. Lecerf, J. Dimitrov, Jelena Lazić, 2019, ACS omega.

Cofactor-mediated protein promiscuity.

J. Dimitrov, T. Vassilev, 2009 .

Insight into the mechanism of the acquired antibody auto-reactivity.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2008, Autoimmunity reviews.

Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2

A. Ferguson-Smith, J. Dimitrov, R. Hamilton, 2023, bioRxiv.

The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2014, Blood.

Polyreactivity of antibodies from different B-cell subpopulations is determined by distinct sequence patterns of variable region

M. Lecerf, J. Dimitrov, Robin V. Lacombe, 2023, bioRxiv.

Anti-IgE IgG autoantibodies isolated from therapeutic normal IgG intravenous immunoglobulin induce basophil activation

S. Kaveri, J. Dimitrov, J. Bayry, 2019, Cellular & Molecular Immunology.

Temperature sensitivity of bat antibodies links metabolic state with antigen-recognition diversity

M. Lecerf, J. Dimitrov, Nia Toshkova, 2023, bioRxiv.

Microbial symphony orchestrated by mucosal IgA

J. Dimitrov, Alejandra Reyes-Ruiz, 2022, Cellular & molecular immunology.

Microbial symphony orchestrated by mucosal IgA

J. Dimitrov, Alejandra Reyes-Ruiz, 2022, Cellular & Molecular Immunology.

ATVB IN FOCUS: Thromboinflammation and Infection

J. Dimitrov, K. Suzuki-Inoue, L. Roumenina, 2023 .

Heme Interacts with C1q and Inhibits the Classical Complement Pathway*

B. Atanasov, S. Kaveri, S. Lacroix-Desmazes, 2011, The Journal of Biological Chemistry.

Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.

S. Miescher, P. Houillier, J. Dimitrov, 2018, JCI insight.

Functional variability of antibodies upon oxidative processes.

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2008, Autoimmunity reviews.

Induced antigen-binding polyreactivity in human serum IgA.

E. A. Vasilenko, M. Lecerf, J. Dimitrov, 2022, Immunobiology.

HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

Alexia Kanyavuz, J. Dimitrov, H. Mouquet, 2023, Nature communications.

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome.

J. Dimitrov, V. Frémeaux-Bacchi, L. Halbwachs‐Mecarelli, 2013, Blood.

Breaking the law: unconventional strategies for antibody diversification

S. Lacroix-Desmazes, Alexia Kanyavuz, J. Dimitrov, 2019, Nature Reviews Immunology.

“Rational Vaccine Design” for HIV Should Take into Account the Adaptive Potential of Polyreactive Antibodies

S. Kaveri, S. Lacroix-Desmazes, M. Kazatchkine, 2011, PLoS pathogens.

A human FVIII inhibitor modulates FVIII surface electrostatics at a VWF‐binding site distant from its epitope

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2010, Journal of thrombosis and haemostasis : JTH.

A human FVIII inhibitor modulates FVIII surface electrostatics at a VWF-binding site distant from its epitope J. D. DIMITROV,* 1 L. T. ROUMENINA,* 1 J.-L. PLANTIER,§ S. ANDRE,* D. SABOULARD,-

S. Kaveri, S. Lacroix-Desmazes, J. Dimitrov, 2010 .

Metrics: journal's impact factor skewed by a single paper

Jagadeesh Bayry, J. Dimitrov, J. Bayry, 2010, Nature.