P. Romero

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Clonotype Selection and Composition of Human CD8 T Cells Specific for Persistent Herpes Viruses Varies with Differentiation but Is Stable Over Time1

D. Speiser, Emanuela M. Iancu, P. Corthésy, 2009, The Journal of Immunology.

BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth

J. Tschopp, P. Romero, K. Hofmann, 1999, The Journal of experimental medicine.

Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity.

P. Romero, R. Perret, S. Sierro, 2013, Cancer research.

The Human Vaccines Project: A roadmap for cancer vaccine development

J. Banchereau, A. Palucka, E. Gilboa, 2016, Science Translational Medicine.

CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis

P. Romero, B. Salomé, C. Jandus, 2015, Haematologica.

Combination of lentivector immunization and low‐dose chemotherapy or PD‐1/PD‐L1 blocking primes self‐reactive T cells and induces anti‐tumor immunity

P. Romero, R. Perret, S. Sierro, 2011, European journal of immunology.

Toll-like Receptor 3 Expressed by Melanoma Cells as a Target for Therapy?

P. Romero, S. Lebecque, S. Matikainen, 2007, Clinical Cancer Research.

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides.

P. Romero, C. Widmann, D. Valmori, 1992, Journal of immunological methods.

The interaction of antigenic peptides with the H-2Kd MHC class I molecule.

J. Casanova, R. Lüthy, P. Romero, 1993, Seminars in immunology.

Matrix metalloproteinase 9 (MMP-9/gelatinase B) proteolytically cleaves ICAM-1 and participates in tumor cell resistance to natural killer cell-mediated cytotoxicity

Pedro Romero, Ivan Stamenkovic, I. Stamenkovic, 2002, Oncogene.

Proteasome-Assisted Identification of a SSX-2-Derived Epitope Recognized by Tumor-Reactive CTL Infiltrating Metastatic Melanoma1

Danila Valmori, Hans-Georg Rammensee, Pedro Romero, 2002, The Journal of Immunology.

Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells.

P. Romero, B. Janji, F. Mami-Chouaib, 2012, Cancer research.

A functional screen for germ line p53 mutations based on transcriptional activation.

S. Friend, P. Romero, T. Frebourg, 1992, Cancer research.

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.

Pedro Romero, Nathalie Rufer, Bart Deplancke, 2011, The Journal of clinical investigation.

Reverse immunology approach for the identification of CD8 T‐cell‐defined antigens: Advantages and hurdles

P. Romero, S. Viatte, P. Alves, 2006, Immunology and cell biology.

Circulating MELAN‐A/MART‐1 specific cytolytic T lymphocyte precursors in HLA‐A2+ melanoma patients have a memory phenotype

P. Romero, J. Cerottini, D. Rimoldi, 1998, International journal of cancer.

Naturally Acquired MAGE-A10- and SSX-2-Specific CD8+ T Cell Responses in Patients with Hepatocellular Carcinoma1

D. Speiser, P. Romero, H. Macdonald, 2005, The Journal of Immunology.

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells.

D. Speiser, P. Romero, M. Pittet, 2003, Journal of Immunology.

Ectopic Human Telomerase Catalytic Subunit Expression Maintains Telomere Length But Is Not Sufficient for CD8+ T Lymphocyte Immortalization1

P. Romero, M. Amacker, D. Valmori, 2000, The Journal of Immunology.

Subcellular Localization of the Melanoma-associated Protein Melan-AMART-1 Influences the Processing of Its HLA-A2-restricted Epitope*

P. Romero, D. Valmori, K. Muehlethaler, 2001, The Journal of Biological Chemistry.

Lack of tumor recognition by hTERT peptide 540–548‐specific CD8+ T cells from melanoma patients reveals inefficient antigen processing

D. Speiser, P. Romero, D. Valmori, 2001, European journal of immunology.

Human melanoma-specific CD8+ T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2012, Oncoimmunology.

Melan-A/MART-1-Specific CD4 T Cells in Melanoma Patients: Identification of New Epitopes and Ex Vivo Visualization of Specific T Cells by MHC Class II Tetramers1

D. Speiser, P. Romero, K. Thielemans, 2006, The Journal of Immunology.

Specific T Cells by MHC Class II Tetramers Epitopes and Ex Vivo Visualization of Melanoma Patients: Identification of New Melan-A/MART-1-Specific CD4 T Cells in

D. Speiser, P. Romero, K. Thielemans, 2006 .

HLA‐A*0201 restricted CD8+ T‐lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN‐γ ELISPOT

P. Romero, D. Valmori, J. Tiercy, 2000, Parasite immunology.

The CD4-like molecule LAG-3, biology and therapeutic applications

D. Speiser, P. Romero, S. Sierro, 2011, Expert opinion on therapeutic targets.

Recent advances in tumour antigen‐specific therapy: In vivo veritas

D. Speiser, P. Romero, J. Cerottini, 2005, International journal of cancer.

Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2006, Cancer research.

Orthogonal Gene Engineering Enables CD8+ T Cells to Control Tumors through a Novel PD-1+TOX-indifferent Synthetic Effector State

G. Coukos, S. Carmona, P. Romero, 2022, bioRxiv.

Lymphocyte Proliferation T + and Antigen-Experienced CD 8 Distinct Mechanisms Control Human Naive Romero and

P. Romero, N. Rufer, M. Migliaccio, 2006 .

Distinct Mechanisms Control Human Naive and Antigen-Experienced CD8+ T Lymphocyte Proliferation1

P. Romero, N. Rufer, M. Migliaccio, 2006, The Journal of Immunology.

Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients

G. Coukos, D. Speiser, P. Romero, 2020, Journal for immunotherapy of cancer.

Selective Accumulation of Mature DC-Lamp+ Dendritic Cells in Tumor Sites Is Associated with Efficient T-Cell-Mediated Antitumor Response and Control of Metastatic Dissemination in Melanoma

L. Zitvogel, J. Davoust, P. Romero, 2004, Cancer Research.

Allorestricted T lymphocytes with a high avidity T‐cell receptor towards NY‐ESO‐1 have potent anti‐tumor activity

D. Busch, P. Romero, C. Peschel, 2009, International journal of cancer.

Immune monitoring in cancer immunotherapy.

D. Speiser, P. Romero, V. Cerundolo, 2000, Ernst Schering Research Foundation workshop.

HLA Photoaffinity Labeling Reveals Overlapping Binding of Homologous Melanoma-associated Gene Peptides by HLA-A1, HLA-A29, and HLA-B44 (*)

P. Romero, P. Coulie, C. Jongeneel, 1996, The Journal of Biological Chemistry.

Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1

P. Romero, P. Coulie, C. Jongeneel, 1995, The Journal of experimental medicine.

High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo

G. Ogg, P. Romero, V. Cerundolo, 1998, The Journal of experimental medicine.

Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.

D. Speiser, P. Romero, V. Cerundolo, 1999, Cancer research.

Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Ex Vivo IFN-γ Secretion by Circulating CD8 T Lymphocytes: Implications of a Novel Approach for T Cell Monitoring in Infectious and Malignant Diseases1

D. Speiser, P. Romero, M. Pittet, 2001, The Journal of Immunology.

Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.

D. Schadendorf, E. Thiel, P. Romero, 2002, Cancer research.

Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses.

W. Alvord, B. Fox, H. Maecker, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations.

P. Romero, P. Batard, J. Cerottini, 2002, Cytometry.

Harmonization of Immune Biomarker Assays for Clinical Studies

Sylvia Janetzki, Cedrik M Britten, Marij J P Welters, 2011, Science Translational Medicine.

Structured reporting of T cell assay results.

P. Romero, K. Odunsi, A. Hoos, 2013, Cancer immunity.

Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium

L. Ben-Porat, H. Maecker, M. Kalos, 2009, Cancer Immunology, Immunotherapy.

Assessment of immunogenicity of human Melan-A peptide analogues in HLA-A*0201/Kb transgenic mice.

P. Romero, I. Miconnet, D. Valmori, 1999, Journal of immunology.

An antigen-targeted approach to adoptive transfer therapy of cancer.

P. Romero, V. Cerundolo, D. Valmori, 1999, Cancer research.

Toll-like receptor 3 is necessary for dsRNA adjuvant effects.

P. Romero, B. Salaun, Maude Greutert, 2009, Vaccine.

Antigenicity and immunogenicity of Melan‐A/MART‐1 derived peptides as targets for tumor reactive CTL in human melanoma

D. Speiser, P. Romero, N. Rufer, 2002, Immunological reviews.

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells

G. Coukos, D. Speiser, P. Romero, 2019, Journal of Immunotherapy for Cancer.

Impact of 3 Different Short-term Chemotherapy Regimens on Lymphocyte-depletion and Reconstitution in Melanoma Patients

V. Appay, D. Speiser, V. Voelter, 2010, Journal of immunotherapy.

Cancer Immunotherapy Principles and Practice

Ke Liu, Pedro Romero, Patricia A. Young, 2018 .

Cutting edge: rapid cloning of tumor-specific CTL suitable for adoptive immunotherapy of melanoma.

G. Ogg, P. Romero, V. Cerundolo, 1999, Journal of immunology.

CART cells are prone to Fas- and DR5-mediated cell death

P. Romero, P. Schneider, A. Donda, 2018, Journal of Immunotherapy for Cancer.

Synthetic peptide vaccine confers protection against murine malaria

V. Nussenzweig, P. Barr, P. Romero, 1987, The Journal of experimental medicine.

Metabolic and epigenetic regulation of T-cell exhaustion

P. Romero, Yi-Ru Yu, Ping-Chih Ho, 2020, Nature Metabolism.

Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients

D. Speiser, P. Baumgaertner, P. Romero, 2016, Front. Immunol..

CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.

A. Schulz, P. Romero, D. Gfeller, 2019, Blood advances.

The Era of Cytotoxic CD4 T Cells

P. Romero, C. Jandus, M. Saillard, 2022, Frontiers in Immunology.

Single MHC-Peptide Complex Allo-MHC-Restricted T Cells Specific for a Ex Vivo Characterization of

D. Speiser, P. Romero, M. Pittet, 2006 .

Parenteral is more efficient than mucosal immunization to induce regression of human papillomavirus‐associated genital tumors

P. Romero, J. Schiller, D. Nardelli-Haefliger, 2011, International journal of cancer.

CD40 Agonist Targeted to Fibroblast Activation Protein α Synergizes with Radiotherapy in Murine HPV-Positive Head and Neck Tumors

P. Romero, G. Tolstonog, T. Wyss, 2021, Clinical Cancer Research.

Curtailed T‐cell activation curbs effector differentiation and generates CD8+ T cells with a naturally‐occurring memory stem cell phenotype

P. Romero, K. Pilipow, E. Lugli, 2017, European Journal of Immunology.

Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells

M. Delorenzi, C. Soneson, P. Romero, 2016, EBioMedicine.

Optimum in vitro expansion of human antigen‐specific CD8+ T cells for adoptive transfer therapy

V. Appay, D. Speiser, P. Romero, 2005, Clinical and experimental immunology.

High frequency of functionally active Melan-A specific T cells in a patient with progressive immunoproteasome-deficient melanoma

B. Seliger, M. Rehli, A. Mackensen, 2004, Cancer Cell International.

High Frequency of Functionally Active Melan-A–Specific T Cells in a Patient with Progressive Immunoproteasome-Deficient Melanoma

B. Seliger, M. Rehli, A. Mackensen, 2004, Cancer Research.

MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial

D. Speiser, V. Voelter, P. Romero, 2014, Journal of Translational Medicine.

Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells.

P. Romero, C. Huber, M. Theobald, 2008, Journal of immunology.

An Immunomodulatory Gallotanin-Rich Fraction From Caesalpinia spinosa Enhances the Therapeutic Effect of Anti-PD-L1 in Melanoma

P. Romero, A. Donda, P. Lasso, 2020, Frontiers in Immunology.

Prophylactic vs. Therapeutic Treatment With P2Et Polyphenol-Rich Extract Has Opposite Effects on Tumor Growth

P. Romero, A. Donda, P. Lasso, 2018, Front. Oncol..

This information is current as Dependent Manner − Factor Cells in a Macrophage Migration Inhibitory Central Memory T + Uncommitted CD 4 Promote the Expansion of Human NK Cells + Induced MHC Class II − IL-21

N. Chaput, P. Romero, J. Pallandre, 2016 .

Selective accumulation of differentiated FOXP3+ CD4+ T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood

D. Speiser, P. Romero, C. Jandus, 2008, Cancer Immunology, Immunotherapy.

Generation of cytotoxic T‐cell responses with synthetic melanoma‐associated peptides in vivo: Implications for tumor vaccines with melanoma‐associated antigens

J. Karbach, P. Romero, A. Knuth, 1996, International journal of cancer.

Microenvironment and Immunology Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells

P. Romero, B. Janji, F. Mami-Chouaib, 2012 .

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

P. Romero, G. Berchem, B. Janji, 2011, Cancer research.

Intravaginal TLR agonists increase local vaccine-specific CD8 T-cells and human papillomavirus-associated genital-tumor regression in mice

P. Romero, J. Schiller, L. Derré, 2012, Mucosal Immunology.

The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules

P. Romero, R. Nussenzweig, F. Zavala, 1992, The Journal of experimental medicine.

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

Brian H. Lee, M. Carrington, M. Skobe, 2022, bioRxiv.

Tinkering with nature: the tale of optimizing peptide based cancer vaccines.

D. Speiser, P. Romero, O. Michielin, 2005, Cancer treatment and research.

Testing mouse mammary tumor virus superantigen as adjuvant in cytotoxic T‐lymphocyte responses against a melanoma tumor antigen

P. Romero, I. Miconnet, H. Acha‐Orbea, 2002, International journal of cancer.

CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line.

P. Romero, D. Rimoldi, P. Dietrich, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Recognition of tumor-associated antigens by T-lymphocytes: perspectives for peptide-based vaccines.

P. Romero, D. Liénard, J. Cerottini, 1996, Annals of oncology : official journal of the European Society for Medical Oncology.

The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100.

H. Zarour, J. Renauld, P. Romero, 1996, The Journal of investigative dermatology.

An optimized antigen–protein fusion

J. Hubbell, P. Romero, A. Donda, 2020, Nature Biomedical Engineering.

MHC class I H-2Kd-restricted antigenic peptides: additional constraints for the binding motif.

P. Romero, G. Eberl, C. Servis, 1993, International immunology.

Specific binding of antigenic peptides to cell-associated MHC class I molecules

P. Romero, J. Cerottini, I. Luescher, 1991, Nature.

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

P. Romero, B. Malissen, É. Vivier, 1996, The Journal of experimental medicine.

Antigenic Peptide Immunodominant Melan-A/MART-1 HLA-A*0201-Restricted CTL Specific for the Diversity of the Fine Specificity Displayed by

P. Romero, D. Valmori, F. Jotereau, 1998 .

Production of IL 2 and IFN-gamma by T cells from malaria patients in response to Plasmodium falciparum or erythrocyte antigens in vitro.

P. Romero, M. Patarroyo, H. Wigzell, 1985, Journal of immunology.

Epitope located N‐glycans impair the MHC‐I epitope generation and presentation

P. Romero, S. Petrescu, C. Jandus, 2016, Electrophoresis.

Efficient in vivo induction of CTL by cell-associated covalent H-2Kd-peptide complexes.

P. Romero, I. Luescher, J. Cerottini, 1994, Journal of immunological methods.

Differential stability of antigenic MHC class I-restricted synthetic peptides.

P. Romero, C. Widmann, J. Maryanski, 1991, Journal of immunology.

CD4+ cytolytic T cell clone confers protection against murine malaria

P. Romero, M. Tsuji, R. Nussenzweig, 1990, The Journal of experimental medicine.

H-2Kd-restricted antigenic peptides share a simple binding motif

P. Romero, I. Luescher, J. Maryanski, 1991, The Journal of experimental medicine.

CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria.

P. Romero, D. Valmori, G. Eberl, 1995, Immunology letters.

Induction of a cytotoxic T cell response by co‐injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): Further enhancement by pre‐injection of IFA alone

P. Romero, D. Valmori, J. Maryanski, 1994, European journal of immunology.

Conversion of a self peptide sequence into a Kd-restricted neo-antigen by a Tyr substitution

P. Romero, C. Jaulin, C. Drouet, 1991, The Journal of experimental medicine.

The identification of tyrosine as a common key residue in unrelated H-2Kd restricted antigenic peptides.

F. Salemme, P. Romero, T. Boon, 1991, International immunology.

Isolation and characterization of protective cytolytic T cells in a rodent malaria model system.

P. Romero, J. Maryanski, G. Corradin, 1990, Immunology letters.

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Low TCR avidity and lack of tumor cell recognition in CD8+ T cells primed with the CEA-analogue CAP1-6D peptide

P. Romero, G. Parmiani, L. Rivoltini, 2007, Cancer Immunology, Immunotherapy.

Local Salmonella immunostimulation recruits vaccine-specific CD8 T cells and increases regression of bladder tumor

P. Romero, L. Derré, M. Chevalier, 2015, Oncoimmunology.

Induction of Potent Antitumor CTL Responses by Recombinant Vaccinia Encoding a Melan-A Peptide Analogue

P. Romero, V. Cerundolo, I. Miconnet, 2000, The Journal of Immunology.

The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation

P. Romero, P. Umaña, C. Trumpfheller, 2022, Journal for ImmunoTherapy of Cancer.

Lymphocyte Immortalization T + Length But Is Not Sufficient for CD 8 Subunit Expression Maintains Telomere Ectopic Human Telomerase Catalytic

P. Romero, M. Amacker, D. Valmori, 2000 .

Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2008, Proceedings of the National Academy of Sciences.

Assessment of memory formation by metabolically engineered antigen-specific CD8 T cells.

P. Romero, Lianjun Zhang, M. Wenes, 2020, Methods in enzymology.

Harmonisation of short-term in vitro culture for the expansion of antigen-specific CD8+ T cells with detection by ELISPOT and HLA-multimer staining

S. H. van der Burg, M. Welters, P. Romero, 2014, Cancer Immunology, Immunotherapy.

Lymphocytes T + Human Effector-Memory CD 8 Four Functionally Distinct Populations of Rufer

D. Speiser, P. Corthésy, Estelle Devêvre, 2007 .

PD-1 Blockade Unleashes Effector Potential of Both High- and Low-Affinity Tumor-Infiltrating T Cells

P. Romero, A. Donda, D. Zehn, 2018, The Journal of Immunology.

On the significance of CD8αα expression for T cell memory

P. Romero, J. Cerottini, I. Luescher, 2005 .

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients

D. Speiser, P. Romero, N. Rufer, 2013, PloS one.

Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients.

D. Speiser, P. Romero, D. Valmori, 2003, Cancer research.

Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

D. Speiser, P. Baumgaertner, P. Romero, 2013, PloS one.

Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma.

P. Romero, D. Valmori, F. Jotereau, 1997, Journal of immunology.

Peripheral Innate Lymphoid Cells Are Increased in First Line Metastatic Colorectal Carcinoma Patients: A Negative Correlation With Th1 Immune Responses

P. Romero, C. Borg, B. Salomé, 2019, Front. Immunol..

Human primed ILCPs support endothelial activation through NF-κB signaling

P. Romero, P. Schneider, S. Candiani, 2021, eLife.

Immunization with synthetic peptides containing a defined malaria epitope induces a highly diverse cytotoxic T lymphocyte response. Evidence that two peptide residues are buried in the MHC molecule.

J. Casanova, P. Romero, C. Widmann, 1992, Journal of immunology.

In vivo activation of melanoma‐specific CD8+ T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus‐specific T cells

D. Speiser, P. Romero, M. Pittet, 2002, European journal of immunology.

gp100209–2M Peptide Immunization of Human Lymphocyte Antigen-A2+ Stage I-III Melanoma Patients Induces Significant Increase in Antigen-Specific Effector and Long-Term Memory CD8+ T Cells

W. Alvord, B. Fox, H. Maecker, 2004, Clinical Cancer Research.

Lighting up the tumor fire with low-dose irradiation.

G. Coukos, P. Romero, F. Herrera, 2022, Trends in immunology.

iNKT/CD1d-antitumor immunotherapy significantly increases the efficacy of therapeutic CpG/peptide-based cancer vaccine

P. Romero, R. Perret, Stéphanie Corgnac, 2014, Journal of Immunotherapy for Cancer.

Induction of Circulating Tumor-reactive CD8+ T Cells After Vaccination of Melanoma Patients With the gp100209-2M Peptide

B. Fox, P. Romero, S. Meijer, 2007, Journal of immunotherapy.

Reduced L-selectin (CD62LLow) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine.

B. Fox, P. Romero, S. Meijer, 2004, Cellular immunology.

gp 100209 – 2 M Peptide Immunization of Human Lymphocyte Antigen-A 2 Stage I-III Melanoma Patients Induces Significant Increase in Antigen-Specific Effector and Long-Term Memory CD 8 T Cells

W. Alvord, B. Fox, H. Maecker, 2004 .

CpG Are Efficient Adjuvants for Specific CTL Induction Against Tumor Antigen-Derived Peptide

D. Speiser, P. Romero, I. Miconnet, 2002, The Journal of Immunology.

Antigen-Derived Peptide CTL Induction Against Tumor CpG Are Efficient Adjuvants for Specific

D. Speiser, P. Romero, I. Miconnet, 2002 .

Mammalian Target of Rapamycin Complex 1 Orchestrates Invariant NKT Cell Differentiation and Effector Function

P. Romero, M. Rüegg, Stéphanie Corgnac, 2014, The Journal of Immunology.

Differentiation and Effector Function Orchestrates Invariant NKT Cell Mammalian Target of Rapamycin Complex 1

P. Romero, Stéphanie Corgnac, A. Donda, 2014 .

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

D. Speiser, R. Maier, B. Ludewig, 2010, mBio.

High-throughput monitoring of human tumor-specific T-cell responses with large peptide pools

G. Coukos, D. Speiser, P. Romero, 2015, Oncoimmunology.

Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses.

D. Speiser, P. Baumgaertner, P. Romero, 2010, Methods in molecular biology.

Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells.

D. Speiser, P. Romero, D. Peterson, 2006, Journal of immunological methods.

Immuno-monitoring of CD8+ T cells in whole blood versus PBMC samples.

V. Appay, D. Speiser, V. Voelter, 2006, Journal of immunological methods.

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.

D. Speiser, P. Romero, M. Pittet, 2004, Cancer immunity.

Communicated by : LJ Old Ex vivo detectable activation of MelanA-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA

D. Speiser, P. Romero, M. Pittet, 2004 .

Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.

D. Speiser, P. Romero, M. Pittet, 2003, Seminars in cancer biology.

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.

D. Speiser, P. Romero, M. Pittet, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Self-Antigen Specific for a Human Tumor-Associated Selection of the Preimmune Repertoire-Chain in the α Prevalent Role of TCR Cerottini

M. Bonneville, P. Romero, P. Coulie, 2003 .

Disease-driven T cell activation predicts immune responses to vaccination against melanoma.

D. Speiser, P. Romero, P. Batard, 2003, Cancer immunity.

Dissecting TCR‐MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes

P. Romero, D. Valmori, J. Cerottini, 2002, European journal of immunology.

Vaccination with a Melan-A Peptide Selects an Oligoclonal T Cell Population with Increased Functional Avidity and Tumor Reactivity1

P. Romero, M. Pittet, P. Walker, 2002, The Journal of Immunology.

Functional Avidity of Tumor Antigen-Specific CTL Recognition Directly Correlates with the Stability of MHC/Peptide Multimer Binding to TCR1

D. Speiser, P. Romero, D. Valmori, 2002, The Journal of Immunology.

Reactivity Increased Functional Avidity and Tumor an Oligoclonal T Cell Population with Vaccination with a MelanA Peptide Selects

P. Romero, M. Pittet, P. Walker, 2002 .

Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition.

P. Romero, D. Valmori, J. Cerottini, 2002, Cancer immunity.

This information is current as to TCR Stability of MHC / Peptide Multimer Binding theCTL Recognition Directly Correlates with Functional Avidity of Tumor Antigen-Specific Romero and Danila

D. Speiser, P. Romero, D. Valmori, 2002 .

Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.

D. Speiser, P. Romero, D. Valmori, 2001, Cancer research.

Antitumor Activity Avidity-specific Cytolytic T Lymphocytes Show Superior : High 262 − 254 Heterogeneous T-Cell Response to MAGE-A 10 Updated Version

D. Speiser, P. Romero, D. Valmori, 2001 .

Efficient Simultaneous Presentation of NY-ESO-1/LAGE-1 Primary and Nonprimary Open Reading Frame-Derived CTL Epitopes in Melanoma

D. Speiser, P. Romero, D. Valmori, 2000, The Journal of Immunology.

Generation and characterization of malaria‐specific human CD8+ lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells

P. Romero, D. Valmori, J. Oberholzer, 2000, European journal of immunology.

Quantitation of antigen-reactive T cells in peripheral blood by IFNgamma-ELISPOT assay and chromium-release assay: a four-centre comparative trial.

A. Eggermont, P. Romero, C. Scheibenbogen, 2000, Journal of immunological methods.

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.

D. Speiser, U. Şahin, P. Romero, 2000, Cancer research.

T Cells in Melanoma + Melan-A-Specific CD8 Usage Reveals a Large Repertoire of -Chain b Tetramer-Guided Analysis of TCR

D. Speiser, P. Romero, D. Valmori, 2000 .

CTL Epitopes in Melanoma Nonprimary Open Reading Frame-Derived NY-ESO-1 / LAGE-1 Primary and Efficient Simultaneous Presentation of and Danila

D. Speiser, P. Romero, D. Valmori, 2000 .

Immunotherapy of Melanoma Tumor-Specific CTL Suitable for Adoptive Cutting Edge: Rapid Cloning of

G. Ogg, P. Romero, Patrick, 1999 .

Novel methods to monitor antigen-specific cytotoxic T-cell responses in cancer immunotherapy.

P. Romero, G. Waanders, J. Cerottini, 1998, Molecular medicine today.

Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients.

P. Romero, D. Valmori, J. Cerottini, 1997, Cancer research.

Enrichment of Human CD4+ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors 1

D. Speiser, P. Romero, N. Rufer, 2009, The Journal of Immunology.

Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.

P. Romero, D. Valmori, J. Cerottini, 2001, Cancer research.

Enhanced generation of specific tumor-reactive CTL in vitro by Melan-A/Mart-1 immunodominant peptide analogs

P. Romero, D. Valmori, V. Jongeneel, 1997 .

Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.

D. Speiser, P. Romero, N. Rufer, 2009, Cancer research.

Publisher Correction: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

High-throughput Screening of Human Tumor Antigen–specific CD4 T Cells, Including Neoantigen-reactive T Cells

G. Coukos, W. Reith, D. Speiser, 2019, Clinical Cancer Research.

High-throughput screening of human tumor-antigen specific CD4 T cells, 1 including neo-antigen reactive T cells

W. Reith, D. Speiser, P. Baumgaertner, 2019 .

Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.

D. Speiser, P. Romero, V. Cerundolo, 1999, International immunology.

Celebrating a decade of the Journal for ImmunoTherapy of Cancer

P. Hwu, P. Romero, J. Gulley, 2022, Journal for ImmunoTherapy of Cancer.

Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19

F. Marincola, P. Ascierto, M. Atkins, 2020, Journal for ImmunoTherapy of Cancer.

CD28‐negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients

D. Speiser, P. Romero, V. Cerundolo, 1999, European journal of immunology.

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.

J. Schrenzel, D. Speiser, P. Romero, 2007, The Journal of investigative dermatology.

That Can Home to Nonlymphoid Tissues Human Thymus Exports Naive CD8 T Cells

D. Speiser, P. Romero, N. Rufer, 2004 .

Intravesical Bacillus Calmette Guerin Combined with a Cancer Vaccine Increases Local T-Cell Responses in Non-muscle–Invasive Bladder Cancer Patients

D. Speiser, P. Romero, Y. Cerantola, 2016, Clinical Cancer Research.

Cytotoxic T Cells Class I- Dependent Lymphocyte Killing by NLRC5 Deficiency Selectively Impairs MHC

P. Romero, H. Macdonald, A. Tardivel, 2012 .

Construction and characterization of a recombinant adenovirus directing expression of the MAGE‐1 tumor‐specific antigen

P. Romero, C. Jongeneel, J. Schaack, 1997, International journal of cancer.

Vaccination of Melanoma Patients With Melan-A/Mart-1 Peptide and Klebsiella Outer Membrane Protein P40 as an Adjuvant

D. Speiser, P. Baumgaertner, P. Romero, 2009, Journal of immunotherapy.

Safety and exceptional immunogenicity of novel 5T4 viral vectored vaccination regimes in early stage prostate cancer: a phase I clinical trial

F. Hamdy, C. Verrill, P. Romero, 2020 .

NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer.

M. Skobe, R. Sebra, M. Galsky, 2022, Cancer cell.

Advances in Brief Frequent Cytolytic T-Cell Responses to Peptide MAGE-A 10254 – 262 in Melanoma 1

P. Romero, D. Valmori, J. Cerottini, 2001 .

Microenvironment and Immunology Adjuvants That Improve the Ratio of Antigen-Speci fi c Effector to Regulatory T Cells Enhance Tumor Immunity

P. Romero, R. Perret, S. Sierro, 2013 .

MAGE-A3 and MAGE-A4 specific CD4+ T cells in head and neck cancer patients: detection of naturally acquired responses and identification of new epitopes

D. Speiser, P. Romero, P. Monnier, 2010, Cancer Immunology, Immunotherapy.

Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer

D. Speiser, P. Romero, S. Viatte, 2007, Cancer Immunology, Immunotherapy.

A peptide encoded by the human MAGE3 gene and presented by HLA-1344 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3

P. Romero, P. Coulie, P. Bruggen, 2005, Immunogenetics.

Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma

D. Speiser, P. Romero, A. Ianaro, 2020, Cancer Immunology Research.

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.

D. Speiser, P. Romero, M. Pittet, 2002, Trends in immunology.

A New Generation of Melan-A/MART-1 Peptides That Fulfill Both Increased Immunogenicity and High Resistance to Biodegradation: Implication for Molecular Anti-Melanoma Immunotherapy1

B. Monsarrat, P. Romero, D. Valmori, 2001, The Journal of Immunology.

Anti-Melanoma Immunotherapy Biodegradation : Implication for Molecular Immunogenicity and High Resistance to Peptides

B. Monsarrat, P. Romero, D. Valmori, 2001 .

Expression of melan‐a/MART‐1 antigen as a prognostic factor in primary cutaneous melanoma

P. Romero, D. Rimoldi, J. Cerottini, 2001, International journal of cancer.

Cellular and humoral immune responses to a recombinant P. falciparum CS protein in sporozoite-immunized rodents and human volunteers.

P. Barr, P. Romero, D. Herrington, 1990, Bulletin of the World Health Organization.

JITC launches a new section: commentary and editorials

P. Romero, C. Capitini, 2015, Journal of Immunotherapy for Cancer.

Tumor Cell Recognition Efficiency by T Cells

D. Speiser, P. Romero, J. Cerottini, 2005, PLoS medicine.

Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo cell expansion of CMV-reactive CD8 T cells as compared with EBV-reactive CD8 T cells.

P. Romero, N. Rufer, J. Rémy-Martin, 2003, Blood.

Multiple T helper cell epitopes of the circumsporozoite protein of Plasmodium berghei

V. Nussenzweig, P. Barr, P. Romero, 1988, European journal of immunology.

A Novel Approach to Characterize Clonality and Differentiation of Human Melanoma-Specific T Cell Responses: Spontaneous Priming and Efficient Boosting by Vaccination1

D. Speiser, P. Corthésy, P. Baumgaertner, 2006, The Journal of Immunology.

T cells: Functional and molecular analysis of vaccine elicited T-cell responses in melanoma

D. Speiser, P. Baumgaertner, V. Voelter, 2008 .

An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain.

D. Speiser, A. Pica, V. Voelter, 2008, Cancer Immunity.

Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope.

J. Berzofsky, D. Carbone, P. Romero, 1999, International journal of radiation oncology, biology, physics.

Tumor Resident Memory T Cells: New Players in Immune Surveillance and Therapy

P. Romero, S. Labiano, Nina Dumauthioz, 2018, Front. Immunol..

Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?

D. Speiser, P. Romero, J. Cerottini, 2002, Cancer immunity.

Leishmania major infection in mice primes for specific major histocompatibility complex class I‐restricted CD8+ cytotoxic T cell responses

P. Romero, J. Louis, B. Perlaza, 1994, European journal of immunology.

The human melanoma antigen-encoding gene, MAGE-1, is expressed by other tumour cells of neuroectodermal origin such as glioblastomas and neuroblastomas.

P. Romero, D. Rimoldi, S. Carrel, 1993, International journal of cancer.

Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity

P. Romero, E. Menietti, A. Giusti, 2021, Clinical Cancer Research.

Recombinant fusion proteins for targeting dendritic cell subsets in therapeutic cancer vaccine.

P. Romero, N. K. Botelho, Stéphanie Corgnac, 2020, Methods in enzymology.

Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.

D. Speiser, P. Romero, M. Colonna, 2001, Journal of immunology.

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.

A. Mackensen, D. Speiser, P. Romero, 2004, Cancer research.

Prognostic value of arginase‐II expression and regulatory T‐cell infiltration in head and neck squamous cell carcinoma

D. Speiser, P. Romero, P. Monnier, 2013, International journal of cancer.

The SOCS3-Independent Expression of IDO2 Supports the Homeostatic Generation of T Regulatory Cells by Human Dendritic Cells

G. Prendergast, P. Romero, R. Metz, 2014, The Journal of Immunology.

Regulatory Cells by Human Dendritic Cells Supports the Homeostatic Generation of T The SOCS3-Independent Expression of IDO2

G. Prendergast, P. Romero, R. Metz, 2014 .

Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma

M. Juan, P. Romero, K. Benabdellah, 2022, Frontiers in Immunology.

Adherent cells (macrophages?) in tumor-bearing mice suppress MLC responses.

P. Romero, K. Hellström, I. Hellström, 1981, Cellular immunology.

Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines.

P. Romero, J. Fernández, R. Perret, 2012, Vaccine.

Intravaginal and subcutaneous immunization induced vaccine specific CD8 T cells and tumor regression in the bladder.

J. Haefliger, P. Romero, L. Derré, 2014, The Journal of urology.

Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.

Danila Valmori, Pedro Romero, Philippe Guillaume, 2003, Cancer immunity.

The Analysis of the Function and Specificity of T Cells Triggered During Infection with Leishmania , Its Importance for the Rational Design of a Vaccine

P. Romero, J. Louis, F. Conceição-Silva, 1993 .

Morphine attenuates pain and prevents inflammation in experimental peritonitis

P. Romero, J. Cerottini, 2002 .

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

G. Coukos, P. Romero, C. Caux, 2019, Front. Immunol..

Human Effector CD8+ T Lymphocytes Express TLR3 as a Functional Coreceptor1

D. Speiser, P. Romero, N. Rufer, 2006, The Journal of Immunology.

The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis

B. Marinari, P. Romero, A. Costanzo, 2014, Nature Communications.

LiveCount Assay: concomitant measurement of cytolytic activity and phenotypic characterisation of CD8(+) T-cells by flow cytometry.

P. Romero, Y. Mahnke, Estelle F. Devêvre, 2006, Journal of immunological methods.

TLR3 Deficiency in Patients with Herpes Simplex Encephalitis

A. Smahi, J. Casanova, C. Picard, 2007, Science.

Regulation of the immune response in Plasmodium falciparum malaria. III. Proliferative response to antigen in vitro and subset composition of T cells from patients with acute infection or from immune donors.

P. Romero, M. Patarroyo, P. Perlmann, 1984, Clinical and experimental immunology.

Defining the critical hurdles in cancer immunotherapy

Zhigang Tian, Sylvia Janetzki, Cedrik M Britten, 2011, Journal of Translational Medicine.

Activation of MHC class I-restricted CD8+ CTL by microbial T cell mitogens. Dependence upon MHC class II expression of the target cells and V beta usage of the responder T cells.

P. Romero, H. Macdonald, B. Fleischer, 1990, Journal of immunology.

Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth.

P. Romero, L. Michalik, J. Hafner, 2018, Cancer research.

A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria

Pedro Romero, Alberto Moreno, Manuel E. Patarroyo, 1988, Nature.

Therapeutic cancer vaccines revamping: technology advancements and pitfalls

G. Curigliano, P. Romero, M. Disis, 2021, Annals of Oncology.

Metabolic Reprogramming of Terminally Exhausted CD8+ T cells by IL-10 Enhances Anti-Tumor Immunity

P. Romero, Ping-Chih Ho, A. Chaiboonchoe, 2021, Nature Immunology.

Melanoma immunotherapy: past, present, and future.

A. Dashti, P. Romero, I. Klepácek, 2005, Current pharmaceutical design.

Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014

Martin F. Mihm, B. Schilling, F. Marincola, 2013, Journal of Translational Medicine.

Tumour immunity: effector response to tumour and role of the microenvironment

F. Marincola, A. Palucka, A. Mantovani, 2008, The Lancet.

Radioimmunotherapy Combined with Maintenance Anti-CD20 Antibody May Trigger Long-Term Protective T Cell Immunity in Follicular Lymphoma Patients

John O. Prior, S. Larson, D. Speiser, 2013, Clinical & developmental immunology.

Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance.

P. Romero, H. Simon, C. Münz, 2014, The Journal of clinical investigation.

TLR3 as a biomarker for the therapeutic efficacy of double-stranded RNA in breast cancer.

L. Zitvogel, F. André, P. Romero, 2011, Cancer research.

Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides.

D. Speiser, P. Romero, C. Jandus, 2008, Arthritis and rheumatism.

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

V. Nussenzweig, P. Romero, J. Maryanski, 1989, Nature.

CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses

D. Speiser, P. Romero, R. Perret, 2012, Cancer Immunology, Immunotherapy.

Pattern and clinical significance of cancer‐testis gene expression in head and neck squamous cell carcinoma

D. Speiser, P. Romero, P. Monnier, 2011, International journal of cancer.

T cell assays and MIATA: the essential minimum for maximum impact.

M Roederer, S Janetzki, G Pawelec, 2012, Immunity.

A microRNA profile of human CD8+ regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes

A. Burny, P. Romero, P. Martiat, 2014, Journal of Translational Medicine.

Recent advances and hurdles in melanoma immunotherapy

D. Speiser, P. Romero, C. Jandus, 2009, Pigment cell & melanoma research.

CDK4 regulates lysosomal function and mTORC1 activation to promote cancer cell survival.

P. Romero, J. Puyal, L. Fajas, 2019, Cancer research.

Activation to Promote Cancer Cell Survival

P. Romero, J. Puyal, L. Fajas, 2019 .

Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes.

R A Houghten, R Simon, R. Simon, 2001, Cancer research.

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

D. Speiser, P. Romero, V. Cerundolo, 1999, The Journal of experimental medicine.

Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+ T Cells Closely Correlates with CD56 Surface Expression1

D. Speiser, P. Romero, M. Pittet, 2000, The Journal of Immunology.

Type I interferon inhibits interleukin-1 production and inflammasome activation.

Pedro Romero, J. Tschopp, P. Romero, 2011, Immunity.

"MIATA"-minimal information about T cell assays.

Sylvia Janetzki, Cedrik M Britten, Axel Hoos, 2009, Immunity.

Navigating metabolic pathways to enhance antitumour immunity and immunotherapy

P. Romero, S. C. Huang, Ping-Chih Ho, 2019, Nature Reviews Clinical Oncology.

PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

P. Krebs, P. Romero, C. Borg, 2021, Nature Communications.

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

G. Coukos, W. Reith, J. Trapani, 2021, Science Advances.

Impact of Immunotherapy on CD4 T Cell Phenotypes and Function in Cancer

P. Romero, C. Jandus, M. Saillard, 2021, Vaccines.

MicroRNA Profile of Circulating CD4-positive Regulatory T Cells in Human Adults and Impact of Differentially Expressed MicroRNAs on Expression of Two Genes Essential to Their Function*

A. Burny, P. Romero, P. Martiat, 2012, The Journal of Biological Chemistry.

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

A. Burny, P. Romero, P. Martiat, 2009, European journal of immunology.

Sensitive and frequent identification of high avidity neo-epitope specific CD8+ T cells in immunotherapy-naive ovarian cancer

Brian J. Stevenson, G. Coukos, D. Monos, 2018, Nature Communications.

Cyclophosphamide treatment regulates the balance of functional/exhausted tumor-specific CD8+ T cells

P. Romero, M. Moser, O. Leo, 2017, Oncoimmunology.

CD8 T Lymphocytes in Antitumor Immunity

P. Romero, 2016 .

Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope

D. Speiser, P. Baumgaertner, P. Romero, 2016, Oncoimmunology.

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

O. Naveiras, J. Auwerx, G. Coukos, 2019, Cell stem cell.

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire

J. Casanova, P. Romero, P. Kourilsky, 1991, The Journal of experimental medicine.

Mitochondria‐Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells

P. Romero, C. Hess, R. Steiner, 2018, Immunity.

The Activatory Receptor 2B4 Is Expressed In Vivo by Human CD8+ Effector αβ T Cells1

D. Speiser, P. Romero, M. Colonna, 2001, The Journal of Immunology.

MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer.

P. Romero, N. Rufer, Thelma M. Escobar, 2013, Immunity.

Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis.

P. Romero, N. Rufer, P. Reichenbach, 2005, Methods in molecular medicine.

ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells

F. Di Virgilio, M. Colombo, P. Romero, 2017, Front. Immunol..

Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

J. Hubbell, M. Swartz, P. Corthésy, 2014, Cancer immunology research.

Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients

R. Dummer, K. Schwarz, D. Speiser, 2010, Journal of immunotherapy.

Induction of protective immunity against experimental infection with malaria using synthetic peptides

P. Romero, A. Moreno, M. Patarroyo, 1987, Nature.

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

C. Meyer, D. Speiser, P. Baumgaertner, 2015, Proceedings of the National Academy of Sciences.

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

T. Schumacher, R. Morgan, I. Doxiadis, 2007, Blood.

Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity

P. Romero, Ping-Chih Ho, L. Fajas, 2020, Cellular & Molecular Immunology.

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

J. Tschopp, L. French, M. Hahne, 1996, Science.

Cross-presenting human γδ T cells induce robust CD8+ αβ T cell responses

R. Tampé, M. Eberl, P. Romero, 2009, Proceedings of the National Academy of Sciences.

C O M M E N T a R Y Open Access

P. Romero, E. Romano, 2022 .

Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells

S. Carmona, P. Romero, S. Labiano, 2020, Frontiers in Immunology.

Faculty Opinions recommendation of NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment.

P. Romero, 2002 .

Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets

Pedro Romero, Brigitte Autran, Victor Appay, 2011, Journal of Translational Medicine.

Consensus nomenclature for CD 8 T cell phenotypes in cancer

S. H. van der Burg, J. Blay, F. Marincola, 2015 .

Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues.

P. Romero, D. Valmori, F. Jotereau, 1998, Journal of immunology.

Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes

P. Romero, F. Brasseur, P. Bruggen, 1994, The Journal of experimental medicine.

Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor.

S. Rowland-Jones, V. Appay, C. Pinilla, 2008, International immunology.

Loss of single HLA Class I allospecificities in melanoma cells due to selective genomic abbreviations

R. Dummer, E. Laine, P. Romero, 2002, International journal of cancer.

IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells1

D. Speiser, P. Baumgaertner, P. Romero, 2007, The Journal of Immunology.

Cytolytic T Cells + of Self-Antigen-Specific Human CD 28 IL-12 Controls Cytotoxicity of a Novel Subset Rufer and

D. Speiser, P. Baumgaertner, P. Romero, 2007 .

Identification of tumor-associated antigens by large-scale analysis of genes expressed in human colorectal cancer.

C. V. Jongeneel, Brian J. Stevenson, D. Speiser, 2008, Cancer immunity.

IL-21–Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor–Dependent Manner

N. Chaput, P. Romero, J. Pallandre, 2016, The Journal of Immunology.

Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors.

P. Romero, H. Macdonald, C. Esslinger, 2002, Human gene therapy.

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes1

Pedro Romero, Daniel E. Speiser, Nathalie Rufer, 2007, The Journal of Immunology.

Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond

L. J. Old, S. Janetzki, S. H. van der Burg, 2010, Cancer Immunology, Immunotherapy.

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

Sylvia Janetzki, Axel Hoos, Pedro Romero, 2007, Cancer Immunology, Immunotherapy.

A microRNA profile of human CD8+ regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes

A. Burny, P. Romero, P. Martiat, 2014, Journal of Translational Medicine.

Metabolic Control of CD8+ T Cell Fate Decisions and Antitumor Immunity.

P. Romero, Lianjun Zhang, 2018, Trends in molecular medicine.

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.

P. Romero, L. Fajas, M. Rüegg, 2016, Cell reports.

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

D. Speiser, P. Romero, V. Cerundolo, 1999, The Journal of experimental medicine.

Final Antigenic Melan-A Peptides Produced Directly by the Proteasomes Are Preferentially Selected for Presentation by HLA-A*0201 in Melanoma Cells1

B. Monsarrat, P. Romero, D. Valmori, 2004, The Journal of Immunology.

HLA-A * 0201 in Melanoma Cells Preferentially Selected for Presentation by Directly by the Proteasomes Are Final Antigenic MelanA Peptides Produced Romero and Frédéric Lévy Burlet

B. Monsarrat, P. Romero, D. Valmori, 2004 .

Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression

Pedro Romero, Matthias Theobald, Renate Engel, 2006, Immunologic research.

Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR.

Pedro Romero, Susanne Strand, Philippe Guillaume, 2005, Immunity.

Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus

B. Marinari, M. Falchi, P. Romero, 2020, Scientific Reports.

Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex1

D. Speiser, P. Romero, M. Pittet, 2006, The Journal of Immunology.

Human CD8+ T cells expressing HLA‐DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells

D. Speiser, P. Romero, M. Pittet, 2001, European journal of immunology.

Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

T. Schumacher, D. Speiser, J. Sarria, 2010, The Journal of Immunology.

Delimiting Maximal CD8 T Cell Function Evidence for a TCR Affinity Threshold

Schumacher, D. Speiser, J. Sarria, 2010 .

Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors.

J. Tschopp, P. Romero, J. Engel, 2000, Journal of immunological methods.

OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway

P. Romero, I. Miconnet, T. Baussant, 2000, Nature Immunology.

Regulation of monocyte functional heterogeneity by miR-146a and Relb.

R. Xavier, T. Wurdinger, R. Weissleder, 2012, Cell reports.

Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

G. Ogg, P. Romero, V. Cerundolo, 1998, The Journal of experimental medicine.

Chronic inflammation is regarded as a strong promoter of tumorigenesis.

B. Kyewski, P. Romero, 2010, International journal of cancer.

Post-Thymic Differentiation for CD4+ and Human T Cell Subsets Reveals Parallel Sensitive Gene Expression Profiling of

Pedro Romero, Serge Leyvraz, Daniel E. Speiser, 2013 .

Sensitive Gene Expression Profiling of Human T Cell Subsets Reveals Parallel Post-Thymic Differentiation for CD4+ and CD8+ Lineages1

V. Appay, A. Bosio, D. Speiser, 2007, The Journal of Immunology.

Current state of vaccine therapies in non-small-cell lung cancer.

P. Romero, 2008, Clinical lung cancer.

show telomerase activity and are distinct from cytolytic effector T cells

D. Speiser, P. Romero, D. Valmori, 2001 .

BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination.

D. Olive, D. Speiser, P. Romero, 2010, The Journal of clinical investigation.

CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria.

P. Romero, G. Arreaza, G. Arreaza, 1991, International immunology.

Highly diverse T cell recognition of a single Plasmodium berghei peptide presented by a series of mutant H-2Kd molecules.

J. Casanova, P. Romero, P. Kourilsky, 1992, Journal of immunology.

MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma

Santiago J. Carmona, S. Carmona, D. Speiser, 2019, Cancer Immunology Research.

Potential target antigens for immunotherapy in human pancreatic cancer.

M. Koch, P. Romero, J. Weitz, 2007, Cancer letters.

Vaccine Immunotherapy for a Deadly Disease Like Malignant Melanoma: Where Do We Stand?*

A. Dashti, P. Romero, I. Klepácek, 2005 .

Tetramer-Guided Analysis of TCR β-Chain Usage Reveals a Large Repertoire of Melan-A-Specific CD8+ T Cells in Melanoma Patients1

D. Speiser, P. Romero, V. Cerundolo, 2000, The Journal of Immunology.

Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients.

D. Speiser, P. Romero, D. Valmori, 2001, International immunopharmacology.

Generation of affinity ranged antigen-expressing tumor cell lines.

P. Romero, A. Martinez-Usatorre, 2020, Methods in enzymology.

The Vast Universe of T Cell Diversity: Subsets of Memory Cells and Their Differentiation.

P. Romero, Lianjun Zhang, C. Jandus, 2017, Methods in molecular biology.

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

P. Romero, B. Malissen, É. Vivier, 1995, Nature.

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.

P. Corthésy, P. Romero, N. Rufer, 2003, Blood.

Ex Vivo Analysis of Human Antigen-Specific CD8+ T-Cell Responses: Quality Assessment of Fluorescent HLA-A2 Multimer and Interferon-γ ELISPOT Assays for Patient Immune Monitoring

D. Speiser, P. Romero, M. Pittet, 2004, Journal of immunotherapy.

Toll‐like receptors’ two‐edged sword: when immunity meets apoptosis

P. Romero, S. Lebecque, B. Salaun, 2007, European journal of immunology.

Double-stranded RNA in Breast Cancer TLR 3 as a Biomarker for the Therapeutic Efficacy of

L. Zitvogel, F. André, P. Romero, 2011 .

Human Effector CD 8 T Lymphocytes Express TLR 3 as a Functional Coreceptor 1

D. Speiser, P. Romero, N. Rufer, 2006 .

NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells

J. Tschopp, K. Schroder, W. Reith, 2012, The Journal of Immunology.

Sensitive and frequent identification of high avidity neo-epitope specific CD8+ T cells in immunotherapy-naive ovarian cancer

Brian J. Stevenson, I. Xenarios, G. Coukos, 2018, Nature Communications.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

G. Coukos, B. Neyns, I. Melero, 2019, Journal of Immunotherapy for Cancer.

Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3

P. Romero, V. Cerundolo, D. Valmori, 1999, The Journal of experimental medicine.

Optimized gene engineering of murine CAR-T cells reveals the beneficial effects of IL-15 coexpression

G. Coukos, P. Romero, C. Ronet, 2020, The Journal of experimental medicine.

Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients

D. Speiser, P. Romero, O. Michielin, 2007, Cancer Immunology, Immunotherapy.

The Cooperative Induction of Hypoxia-Inducible Factor-1α and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis12

C. Richon, P. Romero, N. Mazure, 2009, The Journal of Immunology.

miR-155 Overexpression in OT-1 CD8+ T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen

G. Coukos, P. Romero, Ping-Chih Ho, 2019, Molecular therapy oncolytics.

The human T cell response to melanoma antigens.

D. Speiser, P. Romero, J. Cerottini, 2006, Advances in immunology.

An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells

U. Şahin, P. Romero, S. Xue, 2016, Oncotarget.

Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.

Pedro Romero, Philippe Guillaume, Matthias Theobald, 2010, Blood.

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

D. Speiser, P. Romero, N. Rufer, 2005, The Journal of clinical investigation.

Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment

P. Romero, C. Simillion, H. Simon, 2019, Cancer Immunology Research.

Distinct and shared gene expression for human innate versus adaptive helper lymphoid cells

P. Romero, T. Wyss, B. Salomé, 2020, Journal of leukocyte biology.

Cancer Vaccine Design: A Novel Bacterial Adjuvant for Peptide-Specific CTL Induction

P. Romero, I. Miconnet, J. Bonnefoy, 2001, The Journal of Immunology.

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Danila Valmori, Pedro Romero, Daniel E. Speiser, 2002, The Journal of experimental medicine.

Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site1

V. Appay, D. Speiser, V. Voelter, 2006, The Journal of Immunology.

T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?

D. Speiser, P. Romero, C. Münz, 2014, Nature Reviews Immunology.

Deciphering the unusual HLA‐A2/Melan‐A/MART‐1‐specific TCR repertoire in humans

D. Speiser, P. Romero, N. Rufer, 2014, European journal of immunology.

Expression Hierarchy of T Cell Epitopes from Melanoma Differentiation Antigens: Unexpected High Level Presentation of Tyrosinase-HLA-A2 Complexes Revealed by Peptide-Specific, MHC-Restricted, TCR-Like Antibodies1

P. Romero, T. Ziv, Y. Reiter, 2009, The Journal of Immunology.

Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity.

D. Speiser, P. Romero, 2010, Seminars in immunology.

Therapeutic cancer vaccines based on molecularly defined human tumor antigens.

D. Speiser, P. Romero, M. Pittet, 2002, Vaccine.

Peptide and Protein-Based Cancer Vaccines

P. Romero, R. Perret, M. Braun, 2013 .

Cytolytic T lymphocyte responses of cancer patients to tumor-associated antigens

P. Romero, 2004, Springer Seminars in Immunopathology.

Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients.

S. Adams, P. Romero, N. Bhardwaj, 2008, The Journal of investigative dermatology.

SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

D. Speiser, P. Baumgaertner, P. Romero, 2013, The Journal of clinical investigation.

Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.

P. Romero, C. Boitard, S. Rome, 2019, Cell metabolism.

Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1

P. Romero, P. Coulie, C. Jongeneel, 1995, The Journal of experimental medicine.

Successful engineering cancer immunotherapy

G. Coukos, P. Romero, 2014 .

Rationale for immunological approaches to breast cancer therapy.

P. Romero, G. Monnot, 2018, Breast.

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, December 5th 2015

F. Marincola, P. Ascierto, B. Fox, 2016, Journal of Immunotherapy for Cancer.

Circulation but Not in the Tumor Site T Cells in the + Melanoma-Specific CD8 New Generation Vaccine Induces Effective

D. Speiser, V. Voelter, P. Romero, 2015 .

Crystal Structures of Two Closely Related but Antigenically Distinct HLA-A2/Melanocyte-Melanoma Tumor-Antigen Peptide Complexes1

M. Karplus, D. Wiley, P. Romero, 2001, The Journal of Immunology.

Tumor-Antigen Peptide Complexes HLA-A 2 / Melanocyte-Melanoma Antigenically Distinct Crystal Structures of Two Closely Related but C

M. Karplus, D. Wiley, P. Romero, 2001 .

CD8 (cid:98) Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

P. Romero, B. Malissen, É. Vivier, 1996 .

Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial

F. Hamdy, C. Verrill, P. Romero, 2020, Journal for immunotherapy of cancer.

A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-AMART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide1

Olivier Michielin, Vincent Zoete, Pedro Romero, 2007, The Journal of Immunology.

High frequencies of functionally impaired cytokeratin 18‐specific CD8+ T cells in healthy HLA‐A2+ donors

H. Rammensee, S. Stevanović, G. Pawelec, 2005, European journal of immunology.

Discrepancy between ELISPOT IFN-γ secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life

D. Speiser, P. Romero, D. Valmori, 2001, Proceedings of the National Academy of Sciences of the United States of America.

MelanomaTumor-Reactive CTL Infiltrating Metastatic SSX-2-Derived Epitope Recognized by Proteasome-Assisted Identification of a

H. Rammensee, S. Stevanović, M. Pfreundschuh, 2002 .

Redirecting anti-viral CTL against cancer cells by surface targeting of monomeric MHC class I-viral peptide conjugated to antibody fragments.

B. Robert, P. Romero, J. Mach, 2001, Cancer immunity.

Induction Adjuvant for Peptide-Specific CTL Cancer Vaccine Design: A Novel Bacterial

P. Romero, F. Beermann, J. Cerottini, 2013 .

Decapeptide Nonapeptide but Not the Corresponding ImmunodominantMART-1 MelanA Melanoma-Specific CD 8 T Cells Recognizes A Novel Population of Human

D. Speiser, P. Romero, V. Zoete, 2007 .

Prevalent Role of TCR α-Chain in the Selection of the Preimmune Repertoire Specific for a Human Tumor-Associated Self-Antigen1

M. Bonneville, P. Romero, P. Coulie, 2003, The Journal of Immunology.

Positional Scanning-Synthetic Peptide Library-Based Analysis of Self- and Pathogen-Derived Peptide Cross-Reactivity with Tumor-Reactive Melan-A-Specific CTL1

Yingdong Zhao, Clemencia Pinilla, Danila Valmori, 2002, The Journal of Immunology.

Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer+ CD8+ T Cells in Humans

R. Houghten, C. Pinilla, P. Romero, 2002, The Journal of experimental medicine.

Toward synthetic combinatorial peptide libraries in positional scanning format (PS-SCL)-based identification of CD8+ Tumor-reactive T-Cell Ligands: a comparative analysis of PS-SCL recognition by a single tumor-reactive CD8+ cytolytic T-lymphocyte clone.

Yingdong Zhao, Clemencia Pinilla, Danila Valmori, 2002, Cancer research.

Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires.

P. Romero, P. Walker, D. Valmori, 2001, Cancer research.

Nonoverlapping T-Cell Receptor Repertoires Lymphocyte-defined Self-Peptide with Diverse and Melanoma Patients Respond to a Cytotoxic T Updated

P. Romero, P. Walker, D. Valmori, 2001 .

Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide.

P. Romero, D. Valmori, F. Jotereau, 1998, Journal of immunology.

Toward improved immunocompetence of adoptively transferred CD8+ T cells.

D. Speiser, P. Romero, 2005, The Journal of clinical investigation.

in Human T Cells β α Favors Specific Pairing of Introduced TCR Interface β α Molecular Design of the C

Pedro Romero, Philippe Guillaume, Christoph Huber, 2013 .

Molecular Design of the Cαβ Interface Favors Specific Pairing of Introduced TCRαβ in Human T Cells1

P. Romero, C. Huber, M. Theobald, 2008, The Journal of Immunology.

Intralesional adenovirus-mediated interleukin-2 gene transfer for advanced solid cancers and melanoma.

R. Dummer, C. Rochlitz, P. Romero, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Lysis Tumor Susceptibility to CTL-Mediated Cell during Hypoxia Induced an Impairment of and STAT 3 α Hypoxia-Inducible Factor-1 The Cooperative Induction of Mami-Chouaib and

C. Richon, P. Romero, N. Mazure, 2009 .

Immune Monitoring Design within the Developmental Pipeline for an Immunotherapeutic or Preventive Vaccine

M. Roederer, P. Romero, D. Bolton, 2012 .

Fine Structural Variations of αβTCRs Selected by Vaccination with Natural versus Altered Self-Antigen in Melanoma Patients1

D. Speiser, P. Corthésy, P. Baumgaertner, 2009, The Journal of Immunology.

Induction of human papillomavirus oncogene‐specific CD8 T‐cell effector responses in the genital mucosa of vaccinated mice

P. Romero, B. Corthésy, D. Nardelli-Haefliger, 2010, International journal of cancer.

A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols

Sylvia Janetzki, Leah Price, Cedrik M Britten, 2011, Journal of Translational Medicine.

In vivo imaging of T cell delivery to tumors after adoptive transfer therapy

R. Weissleder, G. Wojtkiewicz, J. Grimm, 2007, Proceedings of the National Academy of Sciences.

Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model

P. Romero, A. Donda, K. Prieto, 2016, Cell Death and Disease.

Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination

D. Speiser, P. Romero, J. Cerottini, 2004, Cancer Immunology, Immunotherapy.

α3 Domain Mutants of Peptide/MHC Class I Multimers Allow the Selective Isolation of High Avidity Tumor-Reactive CD8 T Cells1

D. Speiser, P. Romero, M. Pittet, 2003, The Journal of Immunology.

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness*

Olivier Michielin, Vincent Zoete, Pedro Romero, 2012, The Journal of Biological Chemistry.

by Vaccination Spontaneous Priming and Efficient Boosting Melanoma-Specific T Cell Responses: and Differentiation of Human A Novel Approach to Characterize Clonality

D. Speiser, P. Corthésy, P. Baumgaertner, 2006 .

Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide

V. Appay, C. Pinilla, D. Speiser, 2006, European journal of immunology.

Decreased specific CD 8 + T cell cross-reactivity of antigen recognition following vaccination with MelanA peptide

V. Appay, C. Pinilla, D. Speiser, 2006 .

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens

P. Romero, J. Carrascosa, S. Hervás-Stubbs, 2020, Journal for immunotherapy of cancer.

Differential Roles of T Cell Receptor α and β Chains in Ligand Binding Among H-2Kd-restricted Cytolytic T Lymphocyte Clones Specific for a Photoreactive Plasmodium berghei Circumsporozoite Peptide Derivative *

P. Romero, C. Jongeneel, J. Cerottini, 1997, The Journal of Biological Chemistry.

Differential T cell receptor photoaffinity labeling among H-2Kd restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative. Labeling of the alpha-chain correlates with J alpha segment usage

J. Casanova, P. Romero, I. Luescher, 1993, The Journal of experimental medicine.

Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1157–165 by interacting with its central Met/Trp residues

D. Speiser, P. Baumgaertner, P. Romero, 2008, Proceedings of the National Academy of Sciences.

Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative.

M. Peitsch, P. Romero, C. Jongeneel, 1995, Immunity.

Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control

J. Hubbell, M. Swartz, P. Romero, 2019, Front. Immunol..

Amino acid identity and/or position determines the proteasomal cleavage of the HLA-A*0201-restricted peptide tumor antigen MAGE-3271-279.

P. Romero, I. Miconnet, C. Servis, 2000, The Journal of biological chemistry.

Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints.

P. Romero, C. Caux, O. Trédan, 2018, Cancer research.

Degeneracy instead of specificity: is this a solution to cancer immunotherapy?

D. Speiser, P. Romero, M. Pittet, 2002 .

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

P. Romero, G. Guarda, É. Vivier, 2016, Nature Communications.

Valproate Treatment of Human Cord Blood CD4-positive Effector T Cells Confers on Them the Molecular Profile (MicroRNA Signature and FOXP3 Expression) of Natural Regulatory CD4-positive Cells through Inhibition of Histone Deacetylase*

A. Burny, P. Romero, P. Martiat, 2010, The Journal of Biological Chemistry.

CD73 expression in normal and pathological human hepatobiliopancreatic tissues

C. Sempoux, P. Romero, L. de Leval, 2019, Cancer Immunology, Immunotherapy.

CD73 expression in normal, hyperplastic, and neoplastic thyroid: a systematic evaluation revealing CD73 overexpression as a feature of papillary carcinomas

J. Santos, C. Sempoux, P. Romero, 2021, Virchows Archiv.

Longitudinal analysis of DC subsets in patients with ovarian cancer: Implications for immunotherapy

I. Melero, P. Romero, A. Harari, 2023, Frontiers in Immunology.

Dysregulated Innate Lymphocytes in Patients With Primary Antibody Deficiency Treated With Intravenous Immunoglobulin.

P. Romero, A. Helbling, B. Salomé, 2017, Journal of investigational allergology & clinical immunology.

Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand.

P. Romero, I. Luescher, J. Cerottini, 1994, The Journal of biological chemistry.

Photoaffinity labeling of the T cell receptor on living cytotoxic T lymphocytes.

P. Romero, I. Luescher, J. Maryanski, 1993, Journal of immunology.

Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells

Santiago J. Carmona, G. Coukos, S. Carmona, 2023, Nature Immunology.

Gain of HIF1 Activity and Loss of miRNA let-7d Promote Breast Cancer Metastasis to the Brain via the PDGF/PDGFR Axis

M. Delorenzi, P. Romero, G. Lorusso, 2021, Cancer Research.

18F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer

John O. Prior, G. Coukos, S. Peters, 2019, European Journal of Nuclear Medicine and Molecular Imaging.

Virus‐like particles induce robust human T‐helper cell responses

K. Schwarz, D. Speiser, P. Romero, 2012, European journal of immunology.

Staphylococcal enterotoxin-dependent lysis of MHC class II negative target cells by cytolytic T lymphocytes.

P. Romero, H. Macdonald, T. Herrmann, 1991, Journal of immunology.

Combinatorial peptide library‐based identification of peptide ligands for tumor‐reactive cytolytic T lymphocytes of unknown specificity

Clemencia Pinilla, Danila Valmori, Pedro Romero, 2002, European journal of immunology.

Vaccination Route Matters for Mucosal Tumors

P. Romero, D. Nardelli-Haefliger, J. Dudda, 2013, Science Translational Medicine.

Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer.

G. Coukos, I. Melero, P. Romero, 2020, European journal of cancer.

Correction to: CART cells are prone to Fas- and DR5-mediated cell death

G. Coukos, P. Romero, P. Schneider, 2018, Journal of Immunotherapy for Cancer.

Antibody‐conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes

Pedro Romero, Philippe Guillaume, P. Romero, 2000, European journal of immunology.

Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes

D. Speiser, P. Baumgaertner, P. Romero, 2011, Proceedings of the National Academy of Sciences.

Dominant Human CD8 T Cell Clonotypes Persist Simultaneously as Memory and Effector Cells in Memory Phase1

D. Speiser, P. Corthésy, P. Romero, 2009, The Journal of Immunology.

Human Thymus Exports Naive CD8 T Cells That Can Home to Nonlymphoid Tissues1

D. Speiser, P. Romero, N. Rufer, 2004, The Journal of Immunology.

In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration1

H. Pircher, D. Speiser, P. Corthésy, 2007, The Journal of Immunology.

FcgRIIIA (CD16)-expressing monocytes mediate the depletion of tumor-infiltrating Tregs via Ipilimumab-dependent ADCC in melanoma patients

C. Meyer, D. Speiser, P. Baumgaertner, 2014, Journal of Immunotherapy for Cancer.

Most residues on the floor of the antigen binding site of the class I MHC molecule H-2Kd influence peptide presentation.

J. Casanova, P. Romero, P. Kourilsky, 1992, International immunology.

Phenotype and Reactivity of Lymphocytes Expanded from Benign Prostate Hyperplasic Tissues and Prostate Cancer

P. Romero, A. Harari, B. Roth, 2023, Cancers.

Adaptive T-cell immunity and tumor antigen recognition

P. Romero, P. Coulie, 2014 .

CD73 expression and clinical significance in human metastatic melanoma

P. Romero, L. de Leval, I. Treilleux, 2018, Oncotarget.

T Cells in Tumor Immunity

D. Speiser, P. Romero, M. Pittet, 2003 .

Siglec-7/-9 ligands shield tumor cells from NK cell attack

P. Romero, H. Simon, C. Münz, 2013, Journal of Immunotherapy for Cancer.

Combination of Transient Lymphodepletion With Busulfan and Fludarabine and Peptide Vaccination in a Phase I Clinical Trial for Patients With Advanced Melanoma

V. Appay, D. Speiser, V. Voelter, 2007, Journal of immunotherapy.

Journal for immunotherapy of cancer reviewer acknowledgement 2015

P. Romero, 2016, Journal of Immunotherapy for Cancer.

Assessing the Impact of Persistent HIV Infection on Innate Lymphoid Cells Using In Vitro Models.

S. Nisole, P. Romero, N. Arhel, 2023, ImmunoHorizons.

Detecting and analyzing murine innate lymphoid cells.

P. Romero, C. Jandus, S. Trabanelli, 2020, Methods in enzymology.

CD4+ cytolytic T cell clone confers protection against murine malaria

P. Romero, M. Tsuji, R. Nussenzweig, 1990, The Journal of experimental medicine.

Melan-A/MART-1: Immunogenicity and vaccine strategies

D. Speiser, P. Romero, J. Cerottini, 2003 .

Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014

Martin F. Mihm, B. Schilling, F. Marincola, 2013, Journal of Translational Medicine.

Introducing the society for immunotherapy of cancer’s new journal: journal for immunoTherapy of cancer

F. Marincola, P. Romero, Tara Withington, 2013, Journal of Immunotherapy for Cancer.

Intravaginal and subcutaneous immunization induced vaccine specific CD8 T cells and tumor regression in the bladder.

J. Haefliger, P. Romero, L. Derré, 2014, The Journal of urology.

Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients.

S. Adams, P. Romero, N. Bhardwaj, 2008, Journal of Investigative Dermatology.