N. Rufer

发表

Clonotype Selection and Composition of Human CD8 T Cells Specific for Persistent Herpes Viruses Varies with Differentiation but Is Stable Over Time1

D. Speiser, Emanuela M. Iancu, P. Corthésy, 2009, The Journal of Immunology.

TCRep 3D: An Automated In Silico Approach to Study the Structural Properties of TCR Repertoires

Olivier Michielin, Vincent Zoete, Nathalie Rufer, 2011, PloS one.

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.

Pedro Romero, Nathalie Rufer, Bart Deplancke, 2011, The Journal of clinical investigation.

Oligotyping of HLA-A2, -A3, and -B44 subtypes. Detection of subtype incompatibilities between patients and their serologically matched unrelated bone marrow donors.

D. Speiser, N. Rufer, J. Tiercy, 1994, Human immunology.

Human melanoma-specific CD8+ T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2012, Oncoimmunology.

A stepwise protocol to coat aAPC beads prevents out-competition of anti-CD3 mAb and consequent experimental artefacts.

A. Legat, D. Speiser, P. Baumgaertner, 2012, Journal of immunological methods.

Long-lasting stem cell–like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination

M. Delorenzi, D. Speiser, C. Soneson, 2015, Science Translational Medicine.

Assessing ageing of individual T lymphocytes: Mission impossible?

D. Speiser, Emanuela M. Iancu, N. Rufer, 2008, Mechanisms of Ageing and Development.

Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2006, Cancer research.

Lymphocyte Proliferation T + and Antigen-Experienced CD 8 Distinct Mechanisms Control Human Naive Romero and

P. Romero, N. Rufer, M. Migliaccio, 2006 .

Distinct Mechanisms Control Human Naive and Antigen-Experienced CD8+ T Lymphocyte Proliferation1

P. Romero, N. Rufer, M. Migliaccio, 2006, The Journal of Immunology.

Mechanisms That Limit the In Vitro Proliferative Potential of Human CD8+ T Lymphocytes1

N. Rufer, K. Raj, M. Migliaccio, 2005, The Journal of Immunology.

Antigenicity and immunogenicity of Melan‐A/MART‐1 derived peptides as targets for tumor reactive CTL in human melanoma

D. Speiser, P. Romero, N. Rufer, 2002, Immunological reviews.

Impact of 3 Different Short-term Chemotherapy Regimens on Lymphocyte-depletion and Reconstitution in Melanoma Patients

V. Appay, D. Speiser, V. Voelter, 2010, Journal of immunotherapy.

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

Emanuela M. Iancu, N. Rufer, D. Rueda, 2008, Nature Immunology.

Vaccination‐induced functional competence of circulating human tumor‐specific CD8 T‐cells

D. Speiser, P. Baumgaertner, N. Rufer, 2012, International journal of cancer.

Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4+ T cells

Jan A Rath, N. Rufer, D. Gfeller, 2020, Science Advances.

Optimum in vitro expansion of human antigen‐specific CD8+ T cells for adoptive transfer therapy

V. Appay, D. Speiser, P. Romero, 2005, Clinical and experimental immunology.

Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence

D. Speiser, P. Baumgaertner, N. Rufer, 2015, The Journal of Immunology.

Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.

N. Rufer, R. Humphries, M. Migliaccio, 2001, Blood.

Rapid and Continued T-Cell Differentiation into Long-term Effector and Memory Stem Cells in Vaccinated Melanoma Patients

D. Speiser, Emanuela M. Iancu, P. Baumgaertner, 2016, Clinical Cancer Research.

Novel soluble HLA‐A2/MELAN‐A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma

D. Speiser, P. Baumgaertner, N. Rufer, 2010, International journal of cancer.

HA-1 and the SMCY-derived peptide FIDSYICQV (H-Y) are immunodominant minor histocompatibility antigens after bone marrow transplantation.

N. Rufer, J. Tiercy, B. Chapuis, 1998, Transplantation.

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.

D. Speiser, P. Baumgaertner, N. Rufer, 2015, Cancer research.

Overexpressing Telomerase T Lymphocytes + Potential of Human CD8 Mechanisms Regulating the Proliferative

M. Delorenzi, D. Goldstein, N. Rufer, 2006 .

Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2008, Proceedings of the National Academy of Sciences.

Lymphocytes T + Human Effector-Memory CD 8 Four Functionally Distinct Populations of Rufer

D. Speiser, P. Corthésy, Estelle Devêvre, 2007 .

Transferofthehumantelomerasereversetranscriptase (TERT) gene intoTlymphocytesresultsinextensionofreplicativepotential

N. Rufer, R. Humphries, M. Migliaccio, 2012 .

Identification of swiprosin 1 in human lymphocytes

P. Corthésy, N. Rufer, J. Tissot, 2004, Proteomics.

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients

D. Speiser, P. Romero, N. Rufer, 2013, PloS one.

Telomere Length Dynamics in Normal Individuals and in Patients with Hematopoietic Stem Cell‐Associated Disorders

T. Brümmendorf, P. Lansdorp, N. Young, 2001, Annals of the New York Academy of Sciences.

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer

N. Guex, I. Xenarios, G. Coukos, 2015, Oncoimmunology.

CD8 T cell function and cross-reactivity explored by stepwise increased peptide-HLA versus TCR affinity

D. Speiser, P. Baumgaertner, N. Rufer, 2022, Frontiers in Immunology.

High-resolution histocompatibility testing of a group of sixteen B44-positive, ABDR serologically matched unrelated donor-recipient pairs. Analysis of serologically undisclosed incompatibilities by cellular techniques, isoelectrofocusing, and HLA oligotyping.

D. Speiser, N. Rufer, R. Kressig, 1993, Human immunology.

Sequencing of a novel functional HLA-B44 subtype differing in two residues in the alpha 2 domain.

N. Rufer, J. Tiercy, M. Jeannet, 1994, Tissue antigens.

Case Report: Stepwise Anti-Inflammatory and Anti-SARS-CoV-2 Effects Following Convalescent Plasma Therapy With Full Clinical Recovery

C. Beigelman-Aubry, P. Vollenweider, N. Rufer, 2020, Frontiers in Immunology.

CMV infection not responding to antiviral chemotherapy specific T cells for the treatment of - Infusion of cytomegalovirus (CMV)

H. Rammensee, H. Einsele, L. Kanz, 2013 .

Enrichment of Human CD4+ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors 1

D. Speiser, P. Romero, N. Rufer, 2009, The Journal of Immunology.

Characterization of tumor reactive CD8 T cells induced by peptide vaccination in melanoma patients

N. Rufer, 2010 .

Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.

D. Speiser, P. Romero, N. Rufer, 2009, Cancer research.

for High Functional Competence Antimelanoma T Cell Repertoires Enriched Assessment by NTAmers Reveals Quantitative TCR:pMHC Dissociation Rate

N. Rufer, Sébastien Wieckowski, Daniel, 2015 .

Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell depleting agents

P. Vollenweider, N. Rufer, O. Manuel, 2022, medRxiv.

Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients—Report of a Phase I/IIa Clinical Trial

A. Legat, D. Speiser, P. Baumgaertner, 2015, Clinical Cancer Research.

That Can Home to Nonlymphoid Tissues Human Thymus Exports Naive CD8 T Cells

D. Speiser, P. Romero, N. Rufer, 2004 .

Human memory T cells: lessons from stem cell transplantation.

N. Rufer, B. Chapuis, E. Roosnek, 2001, Trends in immunology.

Oligoclonal expansions in the CD8(+)CD28(-) T cells largely explain the shorter telomeres detected in this subset: analysis by flow FISH.

P. Gregersen, F. Batliwalla, N. Rufer, 2000, Human immunology.

Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms

M. Quadroni, N. Rufer, P. Regamey, 2017, Front. Immunol..

Sequence of a new HLA-B7 variant, B*0707, that differs from the common B*0702 allele by one single residue in the peptide binding groove.

N. Rufer, C. Grundschober, N. Adami, 1997, Tissue antigens.

PPAR (cid:1) but not PPAR (cid:2) Ligands Are Potent Repressors of Major Histocompatibility Complex Class II Induction in Atheroma-Associated Cells

F. Mach, N. Rufer, B. Kwak, 2002 .

Limited Telomere Shortening in Hematopoietic Stem Cells after Transplantation

T. Brümmendorf, P. Lansdorp, N. Rufer, 2001, Annals of the New York Academy of Sciences.

Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation.

T. Brümmendorf, N. Rufer, B. Chapuis, 2001, Blood.

Methods for human CD8(+) T lymphocyte proteome analysis.

N. Rufer, J. Tissot, L. Thadikkaran, 2008, Methods in molecular biology.

Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo cell expansion of CMV-reactive CD8 T cells as compared with EBV-reactive CD8 T cells.

P. Romero, N. Rufer, J. Rémy-Martin, 2003, Blood.

A Novel Approach to Characterize Clonality and Differentiation of Human Melanoma-Specific T Cell Responses: Spontaneous Priming and Efficient Boosting by Vaccination1

D. Speiser, P. Corthésy, P. Baumgaertner, 2006, The Journal of Immunology.

T cells: Functional and molecular analysis of vaccine elicited T-cell responses in melanoma

D. Speiser, P. Baumgaertner, V. Voelter, 2008 .

An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain.

D. Speiser, A. Pica, V. Voelter, 2008, Cancer Immunity.

Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes

N. Rufer, M. Duong, Michael Hebeisen, 2019, Journal of Immunotherapy for Cancer.

Telomere Length Dynamics in Normal and Malignant Hematopoiesis

T. Brümmendorf, P. Lansdorp, N. Rufer, 2000 .

The tumor suppressor p16Ink4a regulates T lymphocyte survival

N. Rufer, H. Macdonald, M. Migliaccio, 2006, Oncogene.

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.

A. Mackensen, D. Speiser, P. Romero, 2004, Cancer research.

Turnover of stem cells, naive and memory T lymphocytes, estimated from telomere fluorescence measurements.

N. Rufer, V. Dragowska, L. Wadsworth, 1999, Cytotherapy.

Molecular characterization of HLA-C incompatibilities in HLA-ABDR-matched unrelated bone marrow donor-recipient pairs. Sequence of two new Cw alleles (Cw*02023 and Cw*0707) and recognition by cytotoxic T lymphocytes.

A. Sanchez‐Mazas, N. Rufer, C. Grundschober, 1997, Tissue antigens.

[Publications of third year medical students after their community-based internships].

N. Rufer, J. Daeppen, A. Pécoud, 2010, Revue medicale suisse.

Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4+ T cells.

Jan A Rath, N. Rufer, D. Gfeller, 2020, Science advances.

Clinical consequences of sensitisation to minor histocompatibility antigens before allogeneic bone marrow transplantation

N. Rufer, B. Chapuis, M. Jeannet, 1998, Bone Marrow Transplantation.

Recognition of major histoincompatibilities after transplantation with marrow from HLA closely matched donors.

N. Rufer, C. Barbey, J. Tiercy, 1997, Transplantation.

HLA-B35-subtype mismatches in ABDR serologically matched unrelated donor-recipient pairs.

D. Speiser, N. Rufer, J. Tiercy, 1994, Human immunology.

Human Effector CD8+ T Lymphocytes Express TLR3 as a Functional Coreceptor1

D. Speiser, P. Romero, N. Rufer, 2006, The Journal of Immunology.

Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy.

Hans-Georg Rammensee, Nathalie Rufer, Hermann Einsele, 2002, Blood.

Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection

Tao Dong, Nathalie Rufer, Susan Little, 2004, PLoS biology.

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

H. Pircher, A. Legat, D. Speiser, 2012, PloS one.

Molecular Insights for Optimizing T Cell Receptor Specificity Against Cancer

D. Speiser, N. Rufer, D. Zehn, 2013, Front. Immunol..

Signaling Mechanisms that Balance Anti-viral, Auto-reactive, and Antitumor Potential of Low Affinity T Cells

D. Speiser, N. Rufer, D. Zehn, 2013 .

PPAR&ggr; but not PPAR&agr; Ligands Are Potent Repressors of Major Histocompatibility Complex Class II Induction in Atheroma-Associated Cells

F. Mach, N. Rufer, B. Kwak, 2002 .

Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients

N. Guex, M. Delorenzi, C. Rivolta, 2021, Frontiers in Immunology.

MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer.

P. Romero, N. Rufer, Thelma M. Escobar, 2013, Immunity.

Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis.

P. Romero, N. Rufer, P. Reichenbach, 2005, Methods in molecular medicine.

Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

Nathalie Rufer, Kaare Christensen, Peter M. Lansdorp, 1999, The Journal of experimental medicine.

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

T. Schumacher, R. Morgan, I. Doxiadis, 2007, Blood.

Mechanisms Regulating the Proliferative Potential of Human CD8+ T Lymphocytes Overexpressing Telomerase1

Nathalie Rufer, Mauro Delorenzi, Darlene R Goldstein, 2006, The Journal of Immunology.

Proteomic and transcriptomic analysis of human CD8+ T lymphocytes over‐expressing telomerase

N. Rufer, J. Tissot, L. Thadikkaran, 2007, Proteomics. Clinical applications.

Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry.

T. Brümmendorf, C. Eaves, P. Lansdorp, 2000, Blood.

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry

P. Lansdorp, N. Rufer, E. Roosnek, 1998, Nature Biotechnology.

Understanding the parameters guiding the best practice for treating B‐cell‐depleted patients with COVID‐19 convalescent plasma therapy

N. Rufer, C. Bertelli, D. Gachoud, 2022, British journal of haematology.

Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor.

S. Rowland-Jones, V. Appay, C. Pinilla, 2008, International immunology.

IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells1

D. Speiser, P. Baumgaertner, P. Romero, 2007, The Journal of Immunology.

Cytolytic T Cells + of Self-Antigen-Specific Human CD 28 IL-12 Controls Cytotoxicity of a Novel Subset Rufer and

D. Speiser, P. Baumgaertner, P. Romero, 2007 .

Single cell analysis of the CD8+ T cell response to therapeutic Melan-A peptide vaccination over time

N. Rufer, P. Gannon, 2015 .

Heterogeneity assessment of functional T cell avidity

D. Speiser, P. Baumgaertner, N. Rufer, 2017, Scientific Reports.

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes1

Pedro Romero, Daniel E. Speiser, Nathalie Rufer, 2007, The Journal of Immunology.

High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation.

D. Speiser, N. Rufer, C. Grundschober, 1996, Blood.

Molecular tracking of antigen-specific T-cell clones during immune responses.

N. Rufer, 2005, Current opinion in immunology.

Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94:NKG2C/E and NKD2D killer cell receptors.

N. Rufer, M. Colonna, A. Gratwohl, 2003, Blood.

Histoincompatibilities in ABDR-matched unrelated donor recipient combinations.

D. Speiser, N. Rufer, J. Tiercy, 1995, Bone marrow transplantation.

Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

T. Schumacher, D. Speiser, J. Sarria, 2010, The Journal of Immunology.

Delimiting Maximal CD8 T Cell Function Evidence for a TCR Affinity Threshold

Schumacher, D. Speiser, J. Sarria, 2010 .

Post-Thymic Differentiation for CD4+ and Human T Cell Subsets Reveals Parallel Sensitive Gene Expression Profiling of

Pedro Romero, Serge Leyvraz, Daniel E. Speiser, 2013 .

Sensitive Gene Expression Profiling of Human T Cell Subsets Reveals Parallel Post-Thymic Differentiation for CD4+ and CD8+ Lineages1

V. Appay, A. Bosio, D. Speiser, 2007, The Journal of Immunology.

Does constant regulation of CD8 T cell functional avidity explain its stability?

D. Speiser, N. Rufer, Michael Hebeisen, 2021, European journal of immunology.

Pulmonary Sarcoid–like Granulomatosis after Multiple Vaccinations of a Long-term Surviving Patient with Metastatic Melanoma

D. Speiser, P. Baumgaertner, N. Rufer, 2014, Cancer Immunology Research.

Relation between the resolution of HLA-typing and the chance of finding an unrelated bone marrow donor.

D. Speiser, N. Rufer, J. Tiercy, 1994, Bone marrow transplantation.

MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma

Santiago J. Carmona, S. Carmona, D. Speiser, 2019, Cancer Immunology Research.

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.

P. Corthésy, P. Romero, N. Rufer, 2003, Blood.

Human Effector CD 8 T Lymphocytes Express TLR 3 as a Functional Coreceptor 1

D. Speiser, P. Romero, N. Rufer, 2006 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

High Peptide Dose Vaccination Promotes the Early Selection of Tumor Antigen-Specific CD8 T-Cells of Enhanced Functional Competence

D. Speiser, P. Baumgaertner, N. Rufer, 2020, Frontiers in Immunology.

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

D. Speiser, P. Romero, N. Rufer, 2005, The Journal of clinical investigation.

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Danila Valmori, Pedro Romero, Daniel E. Speiser, 2002, The Journal of experimental medicine.

New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site1

V. Appay, D. Speiser, V. Voelter, 2006, The Journal of Immunology.

Deciphering the unusual HLA‐A2/Melan‐A/MART‐1‐specific TCR repertoire in humans

D. Speiser, P. Romero, N. Rufer, 2014, European journal of immunology.

Murine CD8 T‐cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density

D. Irvine, D. Speiser, N. Rufer, 2019, European journal of immunology.

SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

D. Speiser, P. Baumgaertner, P. Romero, 2013, The Journal of clinical investigation.

Circulation but Not in the Tumor Site T Cells in the + Melanoma-Specific CD8 New Generation Vaccine Induces Effective

D. Speiser, V. Voelter, P. Romero, 2015 .

Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

D. Speiser, N. Rufer, M. Allard, 2015, Front. Immunol..

Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose

D. Speiser, P. Baumgaertner, N. Rufer, 2012, Cancer Immunology, Immunotherapy.

Profile of a Serial Killer: Cellular and Molecular Approaches to Study Individual Cytotoxic T-Cells following Therapeutic Vaccination

D. Speiser, P. Baumgaertner, N. Rufer, 2010, Journal of biomedicine & biotechnology.

Constant regulation for stable CD8 T‐cell functional avidity and its possible implications for cancer immunotherapy

D. Speiser, N. Rufer, Michael Hebeisen, 2021, European Journal of Immunology.

Assessing T Cell Receptor Affinity and Avidity Against Tumor Antigens

N. Rufer, M. Allard, Michael Hebeisen, 2018 .

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Fine Structural Variations of αβTCRs Selected by Vaccination with Natural versus Altered Self-Antigen in Melanoma Patients1

D. Speiser, P. Corthésy, P. Baumgaertner, 2009, The Journal of Immunology.

Impact of Orthologous Melan-A Peptide Immunizations on the Anti-Self Melan-A/HLA-A2 T Cell Cross-Reactivity1

D. Speiser, N. Rufer, O. Michielin, 2006, The Journal of Immunology.

Melan-A/HLA-A2 T Cell Cross-Reactivity Immunizations on the Anti-Self Impact of Orthologous Melan-A Peptide

D. Speiser, N. Rufer, O. Michielin, 2006 .

Melan-A / HLA-A 2 T Cell Cross-Reactivity Immunizations on the Anti-Self Impact of Orthologous MelanA Peptide

D. Speiser, N. Rufer, O. Michielin, 2006 .

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness*

Olivier Michielin, Vincent Zoete, Pedro Romero, 2012, The Journal of Biological Chemistry.

by Vaccination Spontaneous Priming and Efficient Boosting Melanoma-Specific T Cell Responses: and Differentiation of Human A Novel Approach to Characterize Clonality

D. Speiser, P. Corthésy, P. Baumgaertner, 2006 .

Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide

V. Appay, C. Pinilla, D. Speiser, 2006, European journal of immunology.

Decreased specific CD 8 + T cell cross-reactivity of antigen recognition following vaccination with MelanA peptide

V. Appay, C. Pinilla, D. Speiser, 2006 .

Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1157–165 by interacting with its central Met/Trp residues

D. Speiser, P. Baumgaertner, P. Romero, 2008, Proceedings of the National Academy of Sciences.

Two specific populations of GABAergic neurons originating from the medial and the caudal ganglionic eminences aid in proper navigation of callosal axons

Y. Yanagawa, N. Kessaris, T. Vitalis, 2013, Developmental neurobiology.

Successful outcome of pregnancy post‐allogeneic stem cell transplant despite severe RH1 alloimmunization: A case report

L. Alberio, N. Rufer, G. Canellini, 2023, British journal of haematology.

Simultaneous Coexpression of Memory-related and Effector-related Genes by Individual Human CD8 T Cells Depends on Antigen Specificity and Differentiation

D. Speiser, N. Rufer, Sébastien Wieckowski, 2012, Journal of immunotherapy.

Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes

D. Speiser, P. Baumgaertner, P. Romero, 2011, Proceedings of the National Academy of Sciences.

Dominant Human CD8 T Cell Clonotypes Persist Simultaneously as Memory and Effector Cells in Memory Phase1

D. Speiser, P. Corthésy, P. Romero, 2009, The Journal of Immunology.

Human Thymus Exports Naive CD8 T Cells That Can Home to Nonlymphoid Tissues1

D. Speiser, P. Romero, N. Rufer, 2004, The Journal of Immunology.

In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration1

H. Pircher, D. Speiser, P. Corthésy, 2007, The Journal of Immunology.

Sequencing of a new HLA-B41 subtype (B*4102) that occurs with a high frequency in the Caucasoid population

N. Rufer, R. Kressig, J. Tiercy, 2004, Immunogenetics.

Characterization of pretransplant CTL activity in "perfectly matched" unrelated bone marrow donor/recipient combinations.

D. Speiser, N. Rufer, J. Tiercy, 1993, Bone marrow transplantation.

Title: Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients–Report

A. Legat, D. Speiser, P. Baumgaertner, 2022 .

Combination of Transient Lymphodepletion With Busulfan and Fludarabine and Peptide Vaccination in a Phase I Clinical Trial for Patients With Advanced Melanoma

V. Appay, D. Speiser, V. Voelter, 2007, Journal of immunotherapy.

HETEROGENEITY OF HLA‐B35: OLIGOTYPING AND DIRECT SEQUENCING FOR B35 SUBTYPES REVEALS A HIGH MISMATCHING RATE IN B35 SEROLOGICALLY COMPATIBLE KIDNEY AND BONE MARROW DONOR/RECIPIENT PAIRS

D. Speiser, N. Rufer, J. Tiercy, 1995, Transplantation.

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

H. Pircher, A. Legat, D. Speiser, 2012, PLoS ONE.

Antibody response and intra‐host viral evolution after plasma therapy in COVID‐19 patients pre‐exposed or not to B‐cell‐depleting agents

P. Vollenweider, N. Rufer, O. Manuel, 2022, British journal of haematology.

Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors

Brian J. Stevenson, G. Coukos, D. Speiser, 2023, Nature communications.

PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells.

F. Mach, N. Rufer, B. Kwak, 2002, Circulation research.

[Telomerase, elixir of life for human cells?].

N. Rufer, M. Nabholz, 2003, Medecine sciences : M/S.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, David M. Schauder, 2016, Journal for ImmunoTherapy of Cancer.

Overall avidity declines in TCR repertoires during latent CMV but not EBV infection

N. Rufer, M. Allard, B. Doix, 2023, Frontiers in immunology.