J. Sissons

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Long-Term Stable Expanded Human CD4+ T Cell Clones Specific for Human Cytomegalovirus Are Distributed in Both CD45RAhigh and CD45ROhigh Populations1

M. Weekes, M. Wills, J. Sissons, 2004, The Journal of Immunology.

Rapid CD8+ T Cell Repertoire Focusing and Selection of High-Affinity Clones into Memory Following Primary Infection with a Persistent Human Virus: Human Cytomegalovirus1

I. T. Ten Berge, M. Wills, J. Sissons, 2007, The Journal of Immunology.

The Memory Cytotoxic T-Lymphocyte (CTL) Response to Human Cytomegalovirus Infection Contains Individual Peptide-Specific CTL Clones That Have Undergone Extensive Expansion In Vivo

M. Weekes, M. Wills, J. Sissons, 1999, Journal of Virology.

Monocyte-derived inhibitor of interleukin 1 induced by human cytomegalovirus

J. Sissons, D. Scott, B. Rodgers, 1985, Transactions of the Association of American Physicians.

Chronic Herpes Virus Infections

J. Sissons, D. Crawford, 1988 .

Cytomegalovirus - its cellular immunology and biology.

J. Sissons, D. Scott, L. Borysiewicz, 1986, Immunology today.

Human cytomegalovirus infection of the monocyte/macrophage lineage in bone marrow

J. Sissons, C. Tysoe, J. Sinclair, 1994, Journal of virology.

Cytotoxic T cells and human herpes virus infections.

J. Sissons, L. Borysiewicz, 1994, Current topics in microbiology and immunology.

IN V I T R O GENERATION OF HUMAN C Y T O T O X IC LYMPHOCYTES BY VIRUS Viral Glycoproteins Induce Nonspecific Cell-mediated Cytotoxicity without Release of Interferon*

M. Buchmeier, J. Sissons, M. Oldstone, 2003 .

In vitro generation of human cytotoxic lymphocytes by virus. Viral glycoproteins induce nonspecific cell-mediated cytotoxicity without release of interferon

M. Buchmeier, J. Sissons, P. Casali, 1981, The Journal of experimental medicine.

Rapid CD8+ T Cell Repertoire Focusing and Selection of High-Affinity Clones into Memory Following Primary Infection with a Persistent Human Virus: Human Cytomegalovirus1

I. T. Ten Berge, M. Wills, J. Sissons, 2007, The Journal of Immunology.

Immunology of Infection

J. Sissons, J. Cohen, L. Borysiewicz, 1994, Immunology and Medicine Series.

Analysis of cytotoxic T-cell responses to human cytomegalovirus infection.

M. Wills, J. Sissons, 2000, Methods in molecular medicine.

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function

M. Wills, J. Sissons, J. Sinclair, 2012, Proceedings of the National Academy of Sciences.

Long-Term Stable Expanded Human CD4 T Cell Clones Specific for Human Cytomegalovirus Are Distributed in Both CD45RA and CD45RO Populations

M. Weekes, M. Wills, J. Sissons, 2004 .

Immune Response to Virus-Infected Cells

J. Sissons, L. Borysiewicz, 1986, Clinics in Immunology and Allergy.

Human natural killer cell lysis of virus‐infected cells. Relationship to expression of the transferrin receptor

J. Sissons, L. Borysiewicz, S. Graham, 1986, European journal of immunology.

Intracellular Sequestration of the NKG2D Ligand ULBP3 by Human Cytomegalovirus

J. Trowsdale, M. Wills, J. Sissons, 2010, The Journal of Immunology.

Heterogeneity amongst natural killer cells revealed by limiting dilution culture; selectivity against virus-infected and tumour cell targets.

J. Sissons, L. Borysiewicz, P. Mason, 1993, Immunology.

Lysis of human cytomegalovirus infected fibroblasts by natural killer cells: demonstration of an interferon-independent component requiring expression of early viral proteins and characterization of effector cells.

J. Sissons, L. Borysiewicz, S. Morris, 1985, Journal of immunology.

Polymorphonuclear cells are not sites of persistence of human cytomegalovirus in healthy individuals.

J. Sissons, G. Hayhurst, J. Sinclair, 1993, The Journal of general virology.

Monocyte-derived inhibitor of interleukin 1 induced by human cytomegalovirus.

J. Sissons, D. Scott, B. Rodgers, 1985, Journal of virology.

Vascular endothelial and smooth muscle cells are unlikely to be major sites of latency of human cytomegalovirus in vivo.

J. Sissons, M. Reeves, M. Goddard, 2004, The Journal of general virology.

Human cytomegalovirus: pathogenesis and models of latency

J. Sissons, J. Sinclair, 1994 .

Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation.

R. Marcus, M. Wills, J. Sissons, 2003, Blood.

Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers.

P. Lehner, P. MacAry, J. Sissons, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Human cytomegalovirus infection.

J. Sissons, L. Borysiewicz, 1989, Thorax.

Status of Cytomegalovirus Prevention and Treatment in 2000.

M. Weekes, M. Wills, J. Sissons, 2000, Hematology. American Society of Hematology. Education Program.

Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells.

J. Sissons, J. Sinclair, L. Borysiewicz, 1991, The Journal of general virology.

Latency and reactivation of human cytomegalovirus.

M. Wills, J. Sissons, J G P Sissons, 2002, The Journal of infection.

Antibody-Mediated Destruction of Virus-Infected Cells

J. Sissons, M. Oldstone, Sissons Jg, 1980, Advances in Immunology.

The Immune Response to Virus Infection

J. Sissons, A. Nash, 1994 .

Cytotoxic lymphocytes generated in vivo with acute measles virus infection.

J. Sissons, M. Oldstone, S. Colby, 1985, Clinical immunology and immunopathology.

Killing of virus-infected cells by cytotoxic lymphocytes.

J. Sissons, M. Oldstone, M. Oldstone, 1980, The Journal of infectious diseases.

Antibody- and Complement-Dependent Lysis of Virus-Infected Cells

J. Sissons, 1984 .

The Immunopathology of Viral and Bacterial Infections

J. Sissons, 1994 .

Purification of measles virus glycoproteins and their integration into artificial lipid membranes.

R. Fujinami, J. Sissons, P. Casali, 1981, The Journal of general virology.

How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future

M. Wills, J. Sissons, Mark R. Wills, 2015, Medical Microbiology and Immunology.

Expression of oncogenic ras in human teratocarcinoma cells induces partial differentiation and permissiveness for human cytomegalovirus infection.

J. Sissons, J. Sinclair, S L Shelbourn, 1989, The Journal of general virology.

An in vitro model for the regulation of human cytomegalovirus latency and reactivation in dendritic cells by chromatin remodelling.

P. Lehner, J. Sissons, M. Reeves, 2005, The Journal of general virology.

The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in non-permissive cells

Ru Liu, Joan Baillie, J. G. Sissons, 1994, Nucleic Acids Res..

Human cytomegalovirus and immunopathology

M. Wills, J. Sissons, A. Carmichael, 2002, Springer Seminars in Immunopathology.

The 21bp repeat element of the human cytomegalovirus major immediate early enhancer is a negative regulator of gene expression in undifferentiated cells.

J Baillie, J. Sissons, J. Sinclair, 1991, Nucleic acids research.

Human cytomegalovirus‐specific cytotoxic T cells: their precursor frequency and stage specificity

J. Sissons, J. Hickling, L. Borysiewicz, 1988, European journal of immunology.

Vaccines against persistent DNA virus infections.

M. Wills, J. Sissons, A. Carmichael, 2002, British medical bulletin.

Alternative complement pathway-mediated lysis of measles virus infected cells: induction by IgG antibody bound to individual viral glycoproteins and comparative efficacy of F(ab')2 and Fab' fragments.

J. Sissons, N. Cooper, M. Oldstone, 1979, Journal of immunology.

Antibody-independent activation of the alternative complement pathway by measles virus-infected cells.

R. Schreiber, J. Sissons, M. Oldstone, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4+ T Cells

Sarah E. Jackson, M. Wills, J. Sissons, 2013, PLoS pathogens.

Vaccines against HIV.

J. Sissons, A. Carmichael, 1995, QJM : monthly journal of the Association of Physicians.

Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses

J. Sissons, J. Hickling, J. Sinclair, 1988, The Journal of experimental medicine.

Clinical aspects and management of cytomegalovirus infection.

J. Sissons, A. Carmichael, A.J Carmichael, 2002, The Journal of infection.

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

X. Jin, M. Weekes, M. Wills, 1996, Journal of virology.

Dynamics of T cell memory in human cytomegalovirus infection

M. Wills, J. Sissons, E. Day, 2008, Medical Microbiology and Immunology.

Human CD28-CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones.

M. Weekes, M. Wills, J. Sissons, 1999, Journal of immunology.

Human Cytomegalovirus Encodes an MHC Class I-Like Molecule (UL142) That Functions to Inhibit NK Cell Lysis1

J. Trowsdale, P. Tomasec, G. Wilkinson, 2005, The Journal of Immunology.

Varicella-zoster virus-specific cytotoxic T lymphocytes (Tc): detection and frequency analysis of HLA class I-restricted Tc in human peripheral blood

J. Sissons, J. Hickling, L. Borysiewicz, 1987, Journal of virology.

Human virus-specific CD8+ CTL clones revert from CD45ROhigh to CD45RAhigh in vivo: CD45RAhighCD8+ T cells comprise both naive and memory cells.

M. Weekes, M. Wills, J. Sissons, 1999, Journal of immunology.

Immune reactive measles virus polypeptides on the cell's surface: turnover and relationship of the glycoproteins to each other and to HLA determinants.

R. Fujinami, J. Sissons, M. Oldstone, 1981, Journal of immunology.

Fine specificity of cellular immune responses in humans to human cytomegalovirus immediate-early 1 protein

N. Alp, J. Sissons, L. Borysiewicz, 1991, Journal of virology.

to CD45RA high In Vivo: CD45RA high CD8 1 T Cells Comprise Both Naive and Memory Cells 1

M. Weekes, M. Wills, J. Sissons, 1999 .

Human cytomegalovirus-specific immunity following haemopoietic stem cell transplantation.

M. Wills, J. Sissons, A. Carmichael, 2003, Blood reviews.

Large clonal expansions of human virus‐specific memory cytotoxic T lymphocytes within the CD57+ CD28– CD8+ T‐cell population

M. Weekes, M. Wills, J. Sissons, 1999, Immunology.

Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells

M. Wills, J. Sissons, S. Jackson, 2014, Journal of Virology.

Epstein Barr virus-specific immune defects in patients with persistent symptoms following infectious mononucleosis.

J. Sissons, A. Rickinson, J. Cohen, 1986, The Quarterly journal of medicine.

Cytomegalovirus Persistent Human Virus : Human Memory Following Primary Infection with a Selection of High-Affinity Clones into T Cell Repertoire Focusing and + Rapid CD 8

J. Sissons, A. Carmichael, E. Day, 2007 .

Progressive loss of IL‐2‐expandable HIV‐1‐specific cytotoxic T lymphocytes during asymptomatic HIV infection

X. Jin, M. Wills, J. Sissons, 1998, European journal of immunology.

Suppressive role of NK cells in pokeweed mitogen-induced immunoglobulin synthesis: effect of depletion/enrichment of Leu 11b+ cells.

J. Sissons, A. Weetman, L. Borysiewicz, 1988, Immunology.

ROhighCD 45 RA Cytomegalovirus Are Distributed in Both Cell Clones Specific for Human T + Long-Term Stable Expanded Human CD 4

M. Weekes, M. Wills, J. Sissons, 2004 .

Functions to Inhibit NK Cell Lysis Class I-Like Molecule (UL142) That Human Cytomegalovirus Encodes an MHC

J. Trowsdale, P. Tomasec, M. Wills, 2005 .

Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line.

J Baillie, J. Sissons, J. Sinclair, 1992, The Journal of general virology.

Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor.

J. Sissons, J. Sinclair, S. Kothari, 1989, Nucleic acids research.

Human cytomegalovirus and monocytes: limited infection and negligible immunosuppression in normal mononuclear cells infected in vitro with mycoplasma-free virus strains.

J. Sissons, D. Scott, C. Freeke, 1989, The Journal of general virology.

stem cell transplantation cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic Late diversification in the clonal composition of human

R. Marcus, M. Wills, J. Sissons, 2013 .

The role of antibody and complement in lysing virus-infected cells

R. Schreiber, J. Sissons, N. Cooper, 2005, Medical Microbiology and Immunology.

LYSIS OF MEASLES VIRUS-INFECTED CELLS BY THE PURIFIED CYTOLYTIC ALTERNATIVE C O M P L E M E N T PATHWAY AND ANTIBODY*

R. Schreiber, J. Sissons, N. Cooper, 2003 .

The Immunology of Cytomegalovirus Infection

J. Sissons, 1986, Journal of the Royal College of Physicians of London.

How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future

M. Wills, J. Sissons, 2015, Medical Microbiology and Immunology.

Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells.

M. Wills, J. Sissons, A. Carmichael, 2007, Blood.

Large HIV‐specific CD8+ cytotoxic T‐lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy

M. Weekes, M. Wills, J. Sissons, 2006, Immunology.

IEl Protein but Can Be Compensated for by Other LTR Regions

J. Sissons, J. Sinclair, C. Hagemeier, 2022 .

The immunosuppressive effects of measles virus on T cell function--failure to affect IL-2 release or cytotoxic T cell activity in vitro.

J. Sissons, L. Borysiewicz, S. Morris, 1985, Clinical and Experimental Immunology.

Progressive loss of IL‐2‐expandable HIV‐1‐specific cytotoxic T lymphocytes during asymptomatic HIV infection

X. Jin, M. Wills, J. Sissons, 1998, European journal of immunology.

Automation of limiting dilution cytotoxicity assays.

N. Alp, J. Sissons, L. Borysiewicz, 1990, Journal of immunological methods.

Short Communication Vascular endothelial and smooth muscle cells are unlikely to be major sites of latency of human cytomegalovirus in vivo

J. Sissons, Jean Chadderton, J H Sinclair, 2004 .

Analysis of cytotoxic T-cell responses to human cytomegalovirus infection.

J. Sissons, Mark R. Wills, 2000, Methods in Molecular Medicine.