L. Kjer-Nielsen

发表

Recognition of Distinct Cross-Reactive Virus-Specific CD8+ T Cells Reveals a Unique TCR Signature in a Clinical Setting

K. Kedzierska, Thi H. O. Nguyen, L. Rowntree, 2014, The Journal of Immunology.

Mucosal‐associated invariant T cell receptor recognition of small molecules presented by MR1

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2018, Immunology and cell biology.

Avidity for antigen can influence the helper dependence of CD8+ T lymphocytes.

L. Kjer-Nielsen, W. Heath, M. Hoffmann, 1993, Journal of immunology.

The Structure of HLA-B8 Complexed to an Immunodominant Viral Determinant: Peptide-Induced Conformational Changes and a Mode of MHC Class I Dimerization1

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2002, The Journal of Immunology.

A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

J. Whisstock, J. McCluskey, J. Rossjohn, 2003 .

A Structural Basis for Varied αβ TCR Usage against an Immunodominant EBV Antigen Restricted to a HLA-B8 Molecule

J. McCluskey, J. Rossjohn, S. Burrows, 2012, The Journal of Immunology.

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

J. McCluskey, J. Rossjohn, John J Miles, 2012, Nature.

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I–bound peptide

Natalie A Borg, Ashley M Buckle, James McCluskey, 2005, Nature Immunology.

T cell allorecognition via molecular mimicry.

James McCluskey, Anthony W Purcell, Zhenjun Chen, 2009, Immunity.

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

James McCluskey, Rajiv Khanna, Anthony W Purcell, 2010, Proceedings of the National Academy of Sciences.

MR1 presents microbial vitamin B metabolites to MAIT cells

Malcolm J. McConville, James McCluskey, Anthony W. Purcell, 2012, Nature.

Identification of a Golgi-localised GRIP domain protein from Arabidopsis thaliana

A. Bacic, R. Teasdale, P. Gilson, 2004, Planta.

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Natalie A. Borg, James McCluskey, Mark J. Smyth, 2006, The Journal of experimental medicine.

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

Spencer J. Williams, G. Besra, S. Turner, 2011, Nature Immunology.

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.

P. Marrack, J. McCluskey, J. Rossjohn, 2009, Immunity.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

Structural insight into natural killer T cell receptor recognition of CD1d.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2007, Advances in experimental medicine and biology.

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

L. K. Ely, T. Beddoe, J. McCluskey, 2005, Nature Immunology.

Antagonism of Antiviral and Allogeneic Activity of a Human Public CTL Clonotype by a Single Altered Peptide Ligand: Implications for Allograft Rejection 1

L. K. Ely, S. Bottomley, T. Beddoe, 2005, The Journal of Immunology.

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

L. Kjer-Nielsen, J. Allison, Jacques F. Miller, 1990, Nature.

Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin.

J. McCluskey, L. Kjer-Nielsen, A. Purcell, 2003, Tissue antigens.

The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family

J. McCluskey, J. Rossjohn, S. Gras, 2011, Haematologica.

Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3

T. Beddoe, J. McCluskey, J. Rossjohn, 2004 .

Peripheral blood mucosal-associated invariant T (MAIT) cells in tuberculosis patients and healthy Mycobacterium tuberculosis-exposed controls.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2020, The Journal of infectious diseases.

Abacavir hypersensitivity in HLA-B57-positive individuals with HIV infection is dependent upon the conventional MHC-I Ag presentation pathway

S. Mallal, J. McCluskey, J. Rossjohn, 2007 .

An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant

M. Hellard, J. McCluskey, J. Rossjohn, 2014, The Journal of Immunology.

Structural basis for a major histocompatibility complex class Ib–restricted T cell response

L. K. Ely, T. Beddoe, J. McCluskey, 2006, Nature Immunology.

Implications for Allograft Rejection by a Single Altered Peptide Ligand: Activity of a Human Public CTL Clonotype Antagonism of Antiviral and Allogeneic

L. K. Ely, S. Bottomley, T. Beddoe, 2005 .

Structure function analysis of in vitro mutated CD4 and major histocompatibility complex class II gene products.

J. McCluskey, L. Kjer-Nielsen, R. Blok, 1990, Journal of autoimmunity.

Unique TCR Signature in a Clinical Setting T Cells Reveals a + Virus-Specific CD8 Recognition of Distinct Cross-Reactive

Thi H. O. Nguyen, K. Kedzierska, L. Rowntree, 2014 .

Multivalent requirement for the stimulation of alloreactive T cells: studies with engineered soluble MHC class I proteins in vitro and in vivo.

D. Margulies, J. McCluskey, L. Kjer-Nielsen, 1990 .

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites

D. Fremont, J. McCluskey, J. Rossjohn, 2015, The Journal of Immunology.

Specific for Riboflavin Metabolites Mucosal-Associated Invariant T Cells Antimycobacterial Effects of Mouse Functional Heterogeneity and

D. Fremont, J. McCluskey, J. Rossjohn, 2015 .

Restricted to a HLA-B8 Molecule against an Immunodominant EBV Antigen TCR Usage b a A Structural Basis for Varied

J. McCluskey, J. Rossjohn, S. Burrows, 2011 .

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2019, Science Immunology.

Differential recognition of CD1d- α -galactosyl ceramide by the V β 8.2 and V β 7 semi-invariant NKT T-cell receptors

J. McCluskey, J. Rossjohn, D. Pellicci, 2009 .

Recipient mucosal-associated invariant T cells control GVHD within the colon

P. Hugenholtz, J. McCluskey, J. Rossjohn, 2018, The Journal of clinical investigation.

The GRIP Domain is a Specific Targeting Sequence for a Population of trans‐Golgi Network Derived Tubulo‐Vesicular Carriers

L. Kjer-Nielsen, J. Stow, P. Gleeson, 2001, Traffic.

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

D. Sinderen, J. McCluskey, J. Rossjohn, 2014, Nature.

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2004, Acta crystallographica. Section D, Biological crystallography.

T cell allorecognition and MHC restriction--A case of Jekyll and Hyde?

L. K. Ely, J. McCluskey, J. Rossjohn, 2008, Molecular immunology.

MAITs, MR1 and vitamin B metabolites.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2014, Current opinion in immunology.

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

James McCluskey, Ligong Liu, Zhenjun Chen, 2013, Nature Communications.

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

James McCluskey, Ted H. Hansen, Zhenjun Chen, 2012, The Journal of experimental medicine.

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

James McCluskey, John B. Furness, Ted H. Hansen, 2013, The Journal of experimental medicine.

Characterization and Purification of Mouse Mucosal‐Associated Invariant T (MAIT) Cells

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2019, Current protocols in immunology.

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2017, Nature Immunology.

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

K. Clément, J. McCluskey, J. Rossjohn, 2015, The Journal of clinical investigation.

CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor

Natalie A. Borg, James McCluskey, Jamie Rossjohn, 2007, Nature.

Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors.

James McCluskey, Siew Siew Pang, Jamie Rossjohn, 2009, Immunity.

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

T. Beddoe, J. McCluskey, J. Rossjohn, 2008, The Journal of experimental medicine.

Allelic polymorphism in the T cell receptor and its impact on immune responses

J. McCluskey, J. Rossjohn, R. Brennan, 2010, The Journal of experimental medicine.

MAIT cells protect against pulmonary Legionella longbeachae infection

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2018, Nature Communications.

Legionella protection and vaccination mediated by Mucosal Associated Invariant T (MAIT) cells

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2017, bioRxiv.

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

James McCluskey, Ligong Liu, David P. Fairlie, 2014, The Journal of experimental medicine.

Antigen recognition by CD1d-restricted NKT T cell receptors.

J. McCluskey, J. Rossjohn, D. Pellicci, 2010, Seminars in immunology.

Characterization of Human Mucosal‐associated Invariant T (MAIT) Cells

L. Loh, K. Kedzierska, J. McCluskey, 2019, Current protocols in immunology.

a Hypervariable Viral Determinant Immunodominant TCR Adaptability against An Extensive Antigenic Footprint Underpins

M. Hellard, J. McCluskey, J. Rossjohn, 2014 .

The Golgi-targeting sequence of the peripheral membrane protein p230.

L. Kjer-Nielsen, P. Gleeson, B. Toh, 1999, Journal of cell science.

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

J. McCluskey, J. Rossjohn, John J Miles, 2005, The Journal of experimental medicine.

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

N. K. Williams, T. Beddoe, N. Cowieson, 2010, Nature.

The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2010, Journal of molecular biology.

The shaping of T cell receptor recognition by self-tolerance.

J. McCluskey, J. Rossjohn, S. Burrows, 2009, Immunity.

a Mode of MHC Class I Dimerization Peptide-Induced Conformational Changes Immunodominant Viral Determinant : The Structure of HLA-B 8 Complexed to an and Jamie Rossjohn

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2002 .

Alloreactivity between Disparate Cognate and Allogeneic pMHC-I Complexes Is the Result of Highly Focused, Peptide-dependent Structural Mimicry*

J. McCluskey, J. Rossjohn, R. Brennan, 2006, Journal of Biological Chemistry.

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

Nicholas A Williamson, Natalie A Borg, James McCluskey, 2007, Nature Immunology.

Natural HLA Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion

L. K. Ely, S. Bottomley, T. Beddoe, 2004, The Journal of experimental medicine.

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.

David Nolan, Nicholas A Williamson, James McCluskey, 2008, Immunity.

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2002, Acta crystallographica. Section D, Biological crystallography.

An overview on the identification of MAIT cell antigens

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2018, Immunology and cell biology.

GRIP Domain-mediated Targeting of Two New Coiled-coil Proteins, GCC88 and GCC185, to Subcompartments of the trans-Golgi Network*

L. Kjer-Nielsen, J. Stow, P. Gleeson, 2003, The Journal of Biological Chemistry.

Virus Infection across Diverse Outcomes of Human Hepatitis C Antigen-Driven Patterns of TCR Bias Are Shared

M. Hellard, C. Aitken, J. McCluskey, 2012 .

Antigen-Driven Patterns of TCR Bias Are Shared across Diverse Outcomes of Human Hepatitis C Virus Infection

M. Hellard, C. Aitken, J. McCluskey, 2011, The Journal of Immunology.

Hepatitis C Virus Infection Shared across Diverse Outcomes of Human Antigen-Driven Patterns of TCR Bias Are

M. Hellard, C. Aitken, J. McCluskey, 2010 .

Impaired expression of chimaeric major histocompatibility complex transgenes associated with plasmid sequences

J. McCluskey, L. Kjer-Nielsen, J. Perera, 1992, Transgenic Research.

The extracellular domains of MHC class II molecules determine their processing requirements for antigen presentation.

D. Margulies, J. McCluskey, L. Kjer-Nielsen, 1990, Journal of immunology.

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

James McCluskey, Scott R. Burrows, Anthony W. Purcell, 2003, The Journal of experimental medicine.

Identification of a dominant self‐ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2002, FEBS letters.

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction.

James McCluskey, Anthony W Purcell, Jamie Rossjohn, 2006, Proceedings of the National Academy of Sciences of the United States of America.

CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection1

Natalie A Borg, James McCluskey, Anthony W Purcell, 2005, The Journal of Immunology.

Structural Studies on the αβ T‐cell Receptor

L. K. Ely, J. McCluskey, J. Rossjohn, 2005 .

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2002, Structure.

High Resolution Structures of Highly Bulged Viral Epitopes Bound to Major Histocompatibility Complex Class I

Natalie A Borg, James McCluskey, Anthony W Purcell, 2005, Journal of Biological Chemistry.

Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity.

J Rossjohn, S. Mallal, A. Wu, 2011, Tissue antigens.

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

J. McCluskey, J. Rossjohn, S. Gras, 2018, Nature Communications.

Structural studies on HLA-G: implications for ligand and receptor binding.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2007, Human immunology.

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

L. Loh, K. Kedzierska, J. McCluskey, 2021, bioRxiv.

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.

J. McCluskey, L. Kjer-Nielsen, C. Goodnow, 1991, Proceedings of the National Academy of Sciences of the United States of America.

TCRα Genes Direct MHC Restriction in the Potent Human T Cell Response to a Class I-Bound Viral Epitope1

J. McCluskey, J. Rossjohn, R. Brennan, 2006, The Journal of Immunology.

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

L. K. Ely, T. Beddoe, J. McCluskey, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt.

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Functional and Structural Characteristics of NY-ESO-1-related HLA A2-restricted Epitopes and the Design of a Novel Immunogenic Analogue*

T. Beddoe, J. McCluskey, J. Rossjohn, 2004, Journal of Biological Chemistry.

A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins

R. Teasdale, L. Kjer-Nielsen, P. Gleeson, 1999, Current Biology.

The Structure of H-2Kb and Kbm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance

S. Bottomley, T. Beddoe, J. McCluskey, 2004, The Journal of Immunology.

The Structure of H-2Kb and Kbm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance12

S. Bottomley, T. Beddoe, J. McCluskey, 2004, The Journal of Immunology.

This information is current as Selection and Viral Resistance Switch That Governs T Cell Repertoire Determinant : Evidence for a Conformational Complexed to a Herpes Simplex Virus bm 8 and KbThe Structure of H-2

S. Bottomley, T. Beddoe, J. McCluskey, 2004 .

MAIT cells protect against pulmonary Legionella longbeachae infection

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2018, Nature Communications.

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

J. McCluskey, J. Rossjohn, S. Gras, 2018, Nature Communications.

The structural bases of direct T‐cell allorecognition: implications for T‐cell‐mediated transplant rejection

J. McCluskey, J. Rossjohn, S. Gras, 2011, Immunology and cell biology.

HLA-B 8 Molecule against an Immunodominant EBV Antigen TCR Usage βα

J. McCluskey, J. Rossjohn, S. Burrows, 2011 .

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.

James McCluskey, Siew Siew Pang, Anthony W Purcell, 2009, Immunity.

T-cell receptor bias and immunity.

J. McCluskey, J. Rossjohn, S. Burrows, 2008, Current opinion in immunology.

Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

G. Besra, J. McCluskey, J. Rossjohn, 2011, Proceedings of the National Academy of Sciences.

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity.

James McCluskey, James C Whisstock, Anthony W Purcell, 2003, Immunity.

Drugs and drug-like molecules can modulate mucosal-associated invariant T cell function

Jeffrey, Jamie, J. McCluskey, 2017 .

Systems biology approaches to metabolic engineering in Streptomycetes : the Phosphoenolpyruvate-Pyruvate-Oxaloacetate node of primary metabolism

N. K. Williams, T. Beddoe, N. Cowieson, 2012 .

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

T. Beddoe, J. McCluskey, J. Rossjohn, 2010, Proceedings of the National Academy of Sciences.

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

T. Beddoe, J. McCluskey, J. Rossjohn, 2008, The Journal of experimental medicine.

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

J. McCluskey, J. Rossjohn, John J Miles, 2005, The Journal of experimental medicine.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

J. McCluskey, L. Kjer-Nielsen, A. Purcell, 2004, Acta crystallographica. Section D, Biological crystallography.