M. Redondo-Horcajo

发表

Aggregated Compound Biological Signatures Facilitate Phenotypic Drug Discovery and Target Elucidation.

P. Petrone, Alvaro Cortés Cabrera, D. Lucena‐Agell, 2016, ACS chemical biology.

Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation.

M. Redondo-Horcajo, I. Barasoain, J. Díaz, 2012, Bioorganic & medicinal chemistry letters.

The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF‐1

M. Redondo-Horcajo, J. Angulo, P. Nieto, 2004, Chembiochem : a European journal of chemical biology.

Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide.

M. Redondo-Horcajo, C. Lourenço, J. Enríquez, 2010, Cardiovascular research.

Signaling by ALK5 mediates TGF-β-induced ET-1 expression in endothelial cells: a role for migration and proliferation

M. Redondo-Horcajo, F. Rodríguez-Pascual, P. ten Dijke, 2007, Journal of Cell Science.

Transforming growth factor-beta receptor requirements for the induction of the endothelin-1 gene.

M. Redondo-Horcajo, F. Rodríguez-Pascual, S. Lamas, 2006 .

Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity

M. Redondo-Horcajo, C. Uriel, P. Cuevas, 2003, Journal of Biological Chemistry.

The Activation of Fibroblast Growth Factors by Heparin: Synthesis, Structure, and Biological Activity of Heparin‐Like Oligosaccharides

M. Redondo-Horcajo, J. Angulo, P. Nieto, 2001, Chembiochem : a European journal of chemical biology.

Role of peroxynitrite in endothelial damage mediated by Cyclosporine A.

M. Redondo-Horcajo, A. Álvarez-Barrientos, J. Navarro-Antolín, 2007, Free radical biology & medicine.

Systemic administration of acidic fibroblast growth factor ameliorates the ischemic injury of the retina in rats

M. Redondo-Horcajo, P. Cuevas, R. Lozano, 1998, Neuroscience Letters.

Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin.

M. Redondo-Horcajo, I. Barasoain, F. Cañada, 2016, Journal of natural products.

Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.

M. Redondo-Horcajo, I. Barasoain, M. Carda, 2013, Organic & biomolecular chemistry.

Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivatives.

M. Redondo-Horcajo, I. Barasoain, M. Carda, 2013, Current medicinal chemistry.

Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.

M. Redondo-Horcajo, I. Barasoain, J. Díaz, 2012, Journal of medicinal chemistry.

Fibroblast growth factor-1 prevents myocardial apoptosis triggered by ischemia reperfusion injury.

M. Redondo-Horcajo, P. Cuevas, G. Giménez-Gallego, 1997, European journal of medical research.

Transforming Growth Factor-β Induces Endothelin-1 Expression Through Activation of the Smad Signaling Pathway

M. Redondo-Horcajo, F. Rodríguez-Pascual, S. Lamas, 2004 .

The Mechanism of the Interactions of Pironetin Analog/Combretastatin A‐4 Hybrids with Tubulin

M. Redondo-Horcajo, I. Barasoain, J. Díaz, 2015, Archiv der Pharmazie.

Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

K. Altmann, M. Redondo-Horcajo, I. Barasoain, 2019, International journal of molecular sciences.

The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl‐Epothilones

K. Altmann, M. Redondo-Horcajo, I. Barasoain, 2014, ChemMedChem.

Structural Basis of Microtubule Stabilization by Discodermolide

M. Steinmetz, M. Redondo-Horcajo, A. Prota, 2017, Chembiochem : a European journal of chemical biology.

Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells

M. Steinmetz, A. Nogales, F. Gago, 2016, ACS omega.

Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents.

M. Redondo-Horcajo, I. Barasoain, J. Yli-Kauhaluoma, 2014, European journal of medicinal chemistry.

1H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor.

M. Redondo-Horcajo, A. Pineda-Lucena, P. Cuevas, 2000, Biochemistry.

Acetylation of hydroxytyrosol enhances its transport across differentiated Caco-2 cell monolayers

M. Redondo-Horcajo, P. Kroon, G. Pereira-Caro, 2011 .

Synthesis and Anti‐Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene‐1,4‐diones

M. Redondo-Horcajo, I. Barasoain, J. Díaz, 2016, Archiv der Pharmazie.

Development of chromanes as novel inhibitors of the uncoupling proteins.

M. Redondo-Horcajo, A. Viso, E. Rial, 2011, Chemistry & biology.

Título artículo / Títol article: Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin

M. Redondo-Horcajo, I. Barasoain, M. Carda, 2014 .

Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones

K. Altmann, M. Redondo-Horcajo, J. Díaz, 2019, Helvetica Chimica Acta.

Fatty acids revert the inhibition of respiration caused by the antidiabetic drug metformin to facilitate their mitochondrial β-oxidation.

M. Redondo-Horcajo, E. Rial, Leonor Rodríguez-Sánchez, 2012, Biochimica et biophysica acta.

Heparin Modulates the Mitogenic Activity of Fibroblast Growth Factor by Inducing Dimerization of its Receptor. A 3D View by Using NMR

I. S. Fernández, M. Redondo-Horcajo, P. Nieto, 2013, Chembiochem : a European journal of chemical biology.

Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Endothelin-1 Expression by a Novel, Redox-Sensitive Mechanism Involving mRNA Stability

M. Redondo-Horcajo, F. Rodríguez-Pascual, A. Martínez-Ruíz, 2008, Molecular and Cellular Biology.

Endothelin-1 expression is strongly repressed by AU-rich elements in the 3'-untranslated region of the gene.

M. Redondo-Horcajo, F. Rodríguez-Pascual, S. Lamas, 2005, The Biochemical journal.

Functional Cooperation Between Smad Proteins and Activator Protein-1 Regulates Transforming Growth Factor-&bgr;–Mediated Induction of Endothelin-1 Expression

Santiago Lamas, M. Redondo-Horcajo, F. Rodríguez-Pascual, 2003, Circulation research.

Compound biological signatures facilitate phenotypic screening and target elucidation

Álvaro Cortés Cabrera, Fernando Diaz, P. Petrone, 2016, bioRxiv.

A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF‐2

M. Redondo-Horcajo, A. Bikfalvi, P. Cuevas, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Integrating magnetic capabilities to intracellular chips for cell trapping

M. Duch, T. Suárez, J. Plaza, 2021, Scientific Reports.

Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation.

M. Redondo-Horcajo, I. Barasoain, P. Lastres, 2018, Oncology reports.

Oxidative and nitrosative stress in kidney disease: a case for cyclosporine A.

M. Redondo-Horcajo, S. Lamas, 2005, Journal of nephrology.

Solution Structure and Interaction with Basic and Acidic Fibroblast Growth Factor of a 3-kDa Human Platelet Factor-4 Fragment with Antiangiogenic Activity* 210

M. Redondo-Horcajo, A. Bikfalvi, P. Cuevas, 2001, The Journal of Biological Chemistry.

Cover Picture: The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF‐1 (ChemBioChem 1/2004)

M. Redondo-Horcajo, J. Angulo, P. Nieto, 2004 .

Transforming growth factor-beta induces endothelin-1 expression through activation of the Smad signaling pathway.

M. Redondo-Horcajo, F. Rodríguez-Pascual, S. Lamas, 2004, Journal of Cardiovascular Pharmacology.

Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide.

M. Redondo-Horcajo, C. Lourenço, J. Enríquez, 2010, Cardiovascular research.