G. Nikiforovich

发表

Modeling flexible loops in the dark-adapted and activated states of rhodopsin, a prototypical G-protein-coupled receptor.

G. Marshall, G. Nikiforovich, 2005, Biophysical journal.

Three-dimensional model for meta-II rhodopsin, an activated G-protein-coupled receptor.

Garland R Marshall, G. Marshall, G. Nikiforovich, 2003, Biochemistry.

Targeting Beta-3 integrin using a linear hexapeptide labeled with a near-infrared fluorescent molecular probe.

Sharon Bloch, Kexian Liang, Yunpeng Ye, 2006, Molecular pharmaceutics.

Conformation-function relationships in LHRH analogs. II. Conformations of LHRH peptide agonists and antagonists.

G R Marshall, G. Marshall, G. Nikiforovich, 2009, International journal of peptide and protein research.

5 – Peptide Conformation: Stability and Dynamics

G. Marshall, G. Nikiforovich, D. Beusen, 1995 .

Complement factor 5a receptor chimeras reveal the importance of lipid‐facing residues in transport competence

J. Klco, G. Nikiforovich, T. Baranski, 2009, The FEBS journal.

Cyclopentapeptides as Rigidified Templates for Probing Interactions with the AT-1 Receptors

G. Marshall, A. Hallberg, G. Lindeberg, 2001 .

Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking

G. Nikiforovich, C. Kieslich, D. Morikis, 2014, BMC biophysics.

Constitutive activity of neural melanocortin receptors.

G. Nikiforovich, Zhi‐qiang Wang, Fan Yang, 2010, Methods in enzymology.

Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis.

G. Chipens, G. Nikiforovich, N. Veretennikova, 2009, International journal of peptide and protein research.

Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor

G. Marshall, G. Nikiforovich, T. Baranski, 2011, Proteins.

Theoretical conformational analysis of the tetrapeptide Ac-cys-pro-leu-gly-NH2

G. Nikiforovich, V. Leonóva, 1978 .

Conformational Movement of F251 Contributes to the Molecular Mechanism of Constitutive Activation in the C5a Receptor

G. Nikiforovich, T. Baranski, S. Sen, 2008, Chemical biology & drug design.

Towards nonpeptide agonists: Design of ‘true’ peptidomimetics

G. Nikiforovich, 1995, Letters in Peptide Science.

Deducing 3D Models of the Activated States for TM Regions of GPCRs by Modeling Constitutively Active Mutants: The Test Case of Opsin

G. Marshall, G. Nikiforovich, 2006 .

A novel, non-statistical method for predicting breaks in transmembrane helices.

G. Nikiforovich, 1998, Protein engineering.

Conformational templates for rational drug design: flexibility of cyclo(D-Pro1-Ala2-Ala3-Ala4-Ala5) in DMSO solution.

Xuan Zhang, G. Marshall, G. Nikiforovich, 2007, Journal of medicinal chemistry.

Molecular Modeling Suggests Conformational Scaffolds Specifically Targeting Five Subtypes of Somatostatin Receptors

S. Achilefu, G. Marshall, G. Nikiforovich, 2007, Chemical biology & drug design.

Studies of conformational isomerism in alpha-melanocyte stimulating hormone by design of cyclic analogues.

V. Hruby, G. Nikiforovich, S. Sharma, 1998, Biopolymers.

A new class of positively charged melanotropin analogs: A new concept in peptide design

V. Hruby, G. Nikiforovich, A. Castrucci, 1993 .

The use of topographical constraints in receptor mapping: investigation of the topographical requirements of the tryptophan 30 residue for receptor binding of Asp-Tyr-D-Phe-Gly-Trp-(N-Me)Nle-Asp-Phe-NH2 (SNF 9007), a cholecystokinin (26-33) analogue that binds to both CCK-B and delta-opioid receptor

V. Hruby, G. Nikiforovich, H. Yamamura, 1996, Journal of medicinal chemistry.

Vinyl sulfide cyclized analogues of angiotensin II with high affinity and full agonist activity at the AT(1) receptor.

A. Hallberg, A. Johansson, G. Lindeberg, 2002, Journal of medicinal chemistry.

Theoretical conformational analysis of oxytocin molecule.

G. Chipens, G. Nikiforovich, V. Leonóva, 2009, International journal of peptide and protein research.

Computational molecular modeling in peptide drug design.

G. Nikiforovich, 2009, International journal of peptide and protein research.

The space structure of a conformationally labile oligopeptide in solution: angiotensin.

G. Nikiforovich, G V Nikiforovich, B Vesterman, 1987, Journal of biomolecular structure & dynamics.

Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.

V. Hruby, G. Nikiforovich, S. Sharma, 1997, Journal of medicinal chemistry.

Design, Synthesis, Biology, and Conformations of Bicyclic α-Melanotropin Analogues

V. Hruby, G. Nikiforovich, M. Hadley, 1995 .

Diastereoselective synthesis of 1-α-phenylethyl-3,3-dimethyldiaziridine. Conformation and configuration of three-membered ring nitrogen heterocycles containing an asymmetric substituent on the nitrogen atom

G. Nikiforovich, R. Kostyanovskii, G. Shustov, 1988 .

Conformational analysis of beta-methyl-para-nitrophenylalanine stereoisomers of cyclo[D-Pen2, D-Pen5]enkephalin by NMR spectroscopy and conformational energy calculations.

V. Hruby, G. Nikiforovich, K. Kövér, 1998, Biopolymers.

Possible conformations involved in the binding of neurotensin, xenopsin and bradykinin molecules to mast cell receptors

G. Chipens, G. Nikiforovich, Y. Betinsh, 1983, FEBS letters.

Models for the A- and B-receptor-bound conformations of CCK-8.

V. Hruby, G. Nikiforovich, 1993, Biochemical and biophysical research communications.

Analogues of cholecystokinin 26–33 selective for B-type CCK receptors possess δ opioid receptor agonist activity in vitro and in vivo: Evidence for similarities in CCK-B and δ opioid receptor requirements

V. Hruby, G. Nikiforovich, T. Burks, 1994 .

Topographical requirements for δ‐selective opioid peptides

Gregory V. Nikiforovich, Victor J. Hruby, Om Prakash, 1991 .

Conformational dependence of the local nuclear overhauser effects in peptides

G. Chipens, G. Nikiforovich, M. Shenderovich, 1984 .

Conformational aspects of antiviral activity of deoxyguanosine acyclic analogues.

A. Golbraikh, G. Nikiforovich, R. Zhuk, 1989, Nucleic acids research.

Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging.

S. Achilefu, S. Bloch, G. Nikiforovich, 2011, Bioorganic & medicinal chemistry letters.

Dynamic space structure of the Leu-enkephalin molecule in DMSO solution.

G. Nikiforovich, E. Liepiņš, J. Saulītis, 1989, Biochimica et biophysica acta.

Structure of the Complement Factor 5a Receptor-Ligand Complex Studied by Disulfide Trapping and Molecular Modeling*

Ian S. Hagemann, Gregory V. Nikiforovich, J. Klco, 2008, Journal of Biological Chemistry.

Sequence-dependent modification of Trp by the Pmc protecting group of Arg during TFA deprotection.

N. Sepetov, M. Lebl, G. Nikiforovich, 2009, International journal of peptide and protein research.

Enkephalin: Structure‐function relationships

G. Chipens, G. Nikiforovich, R. Vegner, 1978, FEBS letters.

Ab initio modeling of small, medium, and large loops in proteins.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Biopolymers.

Computational Approaches in Peptide and Protein Design: An Overview

G. Marshall, G. Nikiforovich, 2009 .

Genetic Analysis of the First and Third Extracellular Loops of the C5a Receptor Reveals an Essential WXFG Motif in the First Loop*

J. Klco, G. Nikiforovich, T. Baranski, 2006, Journal of Biological Chemistry.

Conformational interpretation of intramolecular electron transfer in Met5-enkephalins between Tyr and Met(S:.Br) radical.

G. Nikiforovich, K. Bobrowski, K. Wierzchowski, 1991, Biochimica et biophysica acta.

Ac-[3- and 4-alkylthioproline31]-CCK4 analogs: synthesis and implications for the CCK-B receptor-bound conformation.

G R Marshall, G. Marshall, G. Nikiforovich, 1995, Journal of medicinal chemistry.

Defining the interface between the C-terminal fragment of alpha-transducin and photoactivated rhodopsin.

Christina M. Taylor, G. Marshall, G. Nikiforovich, 2007, Biophysical journal.

Modeling of the complex between transducin and photoactivated rhodopsin, a prototypical G-protein-coupled receptor.

Christina M. Taylor, G. Marshall, G. Nikiforovich, 2007, Biochemistry.

A Comprehensive Structure-Function Map of the Intracellular Surface of the Human C5a Receptor

G. Nikiforovich, T. Baranski, M. Matsumoto, 2007, Journal of Biological Chemistry.

Computational modeling of constitutively active mutants of GPCRs C5a receptor.

G. Nikiforovich, T. Baranski, 2010, Methods in enzymology.

A Comprehensive Structure-Function Map of the Intracellular Surface of the Human C5a Receptor

G. Nikiforovich, T. Baranski, P. Kiser, 2007, Journal of Biological Chemistry.

Comparison of the retinitis pigmentosa mutations in rhodopsin with a functional map of the C5a receptor

G. Nikiforovich, T. Baranski, I. Hagemann, 2006, Vision Research.

Fluorescent lifetime of near infrared dyes for structural analysis of serum albumin

Samuel Achilefu, Walter J. Akers, Mikhail Y. Berezin, 2008, SPIE BiOS.

Ratiometric Analysis of Fluorescence Lifetime for Probing Binding Sites in Albumin with Near‐Infrared Fluorescent Molecular Probes

Samuel Achilefu, Mikhail Y Berezin, Hyeran Lee, 2007, Photochemistry and photobiology.

Possible locally driven folding pathways of TC5b, a 20‐residue protein

R Matthew Fesinmeyer, G. Nikiforovich, Carl Frieden, 2003, Proteins.

Conformation—function relationships for peptide bioregulators as revealed by theoretical conformation analysis

G. Nikiforovich, 1986 .

Combined use of spectroscopic and energy calculation methods for the determination of peptide conformation in solution.

G. Nikiforovich, B. Vesterman, J. Betiņs, 1988, Biophysical chemistry.

X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures.

J. Deschamps, C. George, J. Flippen-Anderson, 2009, The journal of peptide research : official journal of the American Peptide Society.

Solution conformations of the peptide backbone for DPDPE and its beta-MePhe4-substituted analogs.

V. Hruby, G. Nikiforovich, O. Prakash, 2009, International journal of peptide and protein research.

Conformational features responsible for binding of cyclic analogues of enkephalin to opioid receptors. I. Low-energy peptide backbone conformers of analogues containing Phe4.

A. Golbraikh, G. Nikiforovich, M. Shenderovich, 2009, International journal of peptide and protein research.

A model for the δ‐receptor‐bound conformation of enkephalin

G. Nikiforovich, J. Balodis, 1988 .

Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor.

G. Marshall, G. Nikiforovich, T. Baranski, 2008, Biochemistry.

Protein Docking in the Absence of Detailed Molecular Structures

Ilya A. Vakser, I. Vakser, G. Nikiforovich, 1995 .

Conformation-function relationships in LHRH analogs. I. Conformations of LHRH peptide backbone.

G R Marshall, G. Marshall, G. Nikiforovich, 2009, International journal of peptide & protein research.

Structure-Function Organization and Principles of Information Coding in ACTH, α-MSH, Bradykinin and Wasp Kinin Molecules

G. Nikiforovich, V. Klusha, Chipens Gi, 1979 .

Examination of the conformational meaning of “δ-address” in the dermenkephalin sequence

V. Hruby, G. Nikiforovich, 1990 .

Relationships between solution and receptor-bound conformations of dermenkephalin

V. Hruby, G. Nikiforovich, O. Prakash, 1993 .

Conformational features involved in δ-receptor selectivity of dermenkephalin

V. Hruby, G. Nikiforovich, S. Cavagnero, 1991 .

Topographical requirements for delta opioid ligands: The synthesis and biological properties of a cyclic analogue of deltorphin I

R. Horváth, V. Hruby, G. Nikiforovich, 1992 .

Peptide modeling—An overview

G. Marshall, G. Nikiforovich, D. Beusen, 1994 .

Conformationally readdressed CCK‐B/δ‐opioid pepitide ligands

G R Marshall, G. Marshall, G. Nikiforovich, 1995, Biopolymers.

Conformations of the dermenkephalin backbone in DMSO solution by a new approach to the solution conformations of flexible peptides

V. Hruby, G. Nikiforovich, O. Prakash, 1993 .

The space structures of α‐melanotropin

G. Chipens, G. Nikiforovich, M. Shenderovich, 1981 .

Molecular modeling and design of regioselectively addressable functionalized templates with rigidified three-dimensional structures.

M. Mutter, G. Nikiforovich, C. Lehmann, 1999, Biopolymers.

Conformational analysis of two cyclic analogs of angiotensin: implications for the biologically active conformation.

G. Marshall, G. Nikiforovich, J. Kao, 1994, Biochemistry.

Possible bioactive conformations of α‐melanotropin

G. Nikiforovich, S.A. Rozenblit, M.D. Shenderovich, 1984 .

Design of Different Conformational Isomers of the same Peptide: Alpha-Melanotropin,

V. Hruby, G. Nikiforovich, M. Hadley, 1992 .

3D model for TM region of the AT-1 receptor in complex with angiotensin II independently validated by site-directed mutagenesis data.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Biochemical and biophysical research communications.

Novel approach to computer modeling of seven-helical transmembrane proteins: current progress in the test case of bacteriorhodopsin.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Acta biochimica Polonica.

Modeling binding modes of angiotensin II and pseudopeptide analogues to the AT2 receptor.

G. Nikiforovich, A. Karlén, C. Sköld, 2008, Journal of molecular graphics & modelling.

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications.

G. Marshall, G. Nikiforovich, E. Escher, 1996, Journal of medicinal chemistry.

Synthesis and characterization of a macrocyclic near-infrared optical scaffold.

Yunpeng Ye, Carolyn J Anderson, S. Achilefu, 2003, Journal of the American Chemical Society.

Statistical weights of Leu-enkephalin conformers in aqueous solution

G. Chipens, G. Nikiforovich, J. Betiņs, 1986 .

Conformational analysis of [Cpp1, Sar7, Arg8] vasopressin by 1H-NMR spectroscopy and molecular mechanics calculations.

A. Liwo, G. Nikiforovich, F. Kasprzykowski, 2009, International journal of peptide and protein research.

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008

Charles L. Brooks, Adrian W. R. Serohijos, John Moult, 2009, Nature Reviews Drug Discovery.

Modeling the possible conformations of the extracellular loops in G‐protein‐coupled receptors

Garland R Marshall, Christina M. Taylor, G. Marshall, 2010, Proteins.

Conformational features responsible for the binding of cyclic analogues of enkephalin to opioid receptors. III. Probable binding conformations of mu-agonists with phenylalanine in position 3.

A. Golbraikh, G. Nikiforovich, G V Nikiforovich, 2009, International journal of peptide and protein research.

A minimalistic 3D pharmacophore model for cyclopentapeptide CXCR4 antagonists

G. Marshall, G. Nikiforovich, J. Våbenø, 2006, Biopolymers.

Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1 receptor.

G. Marshall, G. Nikiforovich, K. Catt, 2005, The journal of peptide research : official journal of the American Peptide Society.

Three-dimensional recognition requirements for angiotensin agonists: a novel solution for an old problem.

G R Marshall, G. Marshall, G. Nikiforovich, 1993, Biochemical and biophysical research communications.

Insight into the Binding Mode for Cyclopentapeptide Antagonists of the CXCR4 Receptor

Garland R Marshall, G. Marshall, G. Nikiforovich, 2006, Chemical biology & drug design.

Deﬁning the Interface between the C-terminal Fragment of a -Transducin and Photoactivated Rhodopsin

Christina M. Taylor, G. Nikiforovich, G. R. Marshall, 2022 .

Determination of cyclopeptide conformations in solution using NMR data and conformational energy calculations.

G. Chipens, G. Nikiforovich, J. Saulītis, 1988, Biophysical chemistry.

Conformational Model of Signal Transduction in the Transmembrane Region of the AT-1 Receptor

G. Marshall, G. Nikiforovich, 2001 .

3D modeling of the activated states of constitutively active mutants of rhodopsin.

G. Marshall, G. Nikiforovich, 2006, Biochemical and biophysical research communications.

3 D modeling of the activated states of constitutively active mutants of rhodopsin q

G. Marshall, G. Nikiforovich, 2010 .

Structural models for the complex of chemotaxis inhibitory protein of Staphylococcus aureus with the C5a receptor.

G. Nikiforovich, T. Baranski, 2009, Biochemical and biophysical research communications.

CD spectrum and conformational distribution of cyclotuftsin in solution

G. Nikiforovich, B. S. Kataev, J. Balodis, 1985 .

Interactions between Conserved Residues in Transmembrane Helices 2 and 7 during Angiotensin AT1 Receptor Activation

G. Marshall, L. Hunyady, G. Nikiforovich, 2006, Chemical biology & drug design.

Cyclopentapeptides as Flexible Conformational Templates

Garland R. Marshall, Gregory V. Nikiforovich, Katalin E. Kövér, 2000 .