C. Mold

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C-reactive protein: ligands, receptors and role in inflammation.

L. Marnell, C. Mold, T. D. Du Clos, 2005, Clinical immunology.

Brief Definitive Report C-reactive Protein Is Protective against Streptococcus Pneumoniae Infection in Mice*

C. Mold, T. D. Du Clos, S. Nakayama, 2022 .

Effect of gangliosides on activation of the alternative pathway of human complement.

C. Mold, E. Bremer, M. Michalek, 1988, Journal of immunology.

Inhibition of the alternative pathway of human complement by structural analogues of sialic acid.

C. Mold, E. Bremer, M. Michalek, 1988, Journal of immunology.

Activation of human complement by liposomes: serum factor requirement for alternative pathway activation.

C. Mold, H. Gewurz, 1980, Journal of immunology.

Transforming Growth Factor-β, Macrophage Colony-Stimulating Factor and C-Reactive Protein Levels Correlate with CD14highCD16+ Monocyte Induction and Activation in Trauma Patients

C. Mold, T. D. Du Clos, S. West, 2012, PloS one.

Preparation and Isolation of Soluble Antigen ( Ag )-Antibody ( Ab )-Complement ( C ) Complexes ( Ag : Ab : C ) .

V. Nussenzweig, C. Mold, K. Iida, 2003 .

Serum amyloid P component and C-reactive protein opsonize apoptotic cells for phagocytosis through Fcgamma receptors.

C. Mold, T. D. Du Clos, Rebecca Baca, 2002, Journal of autoimmunity.

C3 nephritic factor and hypocomplementaemia in a clinically healthy individual.

C. Mold, H. Gewurz, S. Strauss, 1983, Clinical and experimental immunology.

Quantitative analysis of C4Ab and C4Bb binding to the C3b/C4b receptor (CR1, CD35)

C. Mold, B. Reilly, 1997, Clinical and experimental immunology.

Expression of rabbit C‐reactive protein in transgenic mice

T. Magnuson, C. Mold, Thomas Wagner, 1995, Immunology and cell biology.

Serum Amyloid P Component and C-Reactive Protein Mediate Phagocytosis Through Murine FcgRs

C. Mold, H. Gresham, T. W. Clos, 2000 .

Hyperoxic suppression of Fc-gamma receptor-mediated phagocytosis by isolated murine pulmonary macrophages.

R. Crowell, C. Mold, G. Hallin, 1995, American journal of respiratory cell and molecular biology.

Identification of gp350 as the viral glycoprotein mediating attachment of Epstein-Barr virus (EBV) to the EBV/C3d receptor of B cells: sequence homology of gp350 and C3 complement fragment C3d

G. Nemerow, C. Mold, N. Cooper, 1987, Journal of virology.

Alveolar and interstitial macrophage populations in the murine lung.

R. Crowell, C. Mold, B. Lehnert, 1992, Experimental lung research.

C-reactive protein is involved in natural killer cell-mediated lysis but does not mediate effector-target cell recognition.

C. Mold, D. Graham, B. Johnson, 1987, Immunology.

C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fc Receptors

L. Marnell, C. Mold, J. Verbeek, 2006 .

The role of the spleen in the protective effect of C-reactive protein in Streptococcus pneumoniae infection.

C. Mold, T. D. Du Clos, S. Nakayama, 1983, Clinical and experimental immunology.

Binding of C-reactive protein to the pneumococcal capsule or cell wall results in differential localization of C3 and stimulation of phagocytosis.

K. Edwards, C. Mold, T. Holzer, 1984, Journal of immunology.

C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.

L. Marnell, C. Mold, T. D. Du Clos, 2007, Journal of immunology.

Serum amyloid P component and C-reactive protein mediate phagocytosis through murine Fc gamma Rs.

C. Mold, T. D. Du Clos, H. Gresham, 2001, Journal of immunology.

Complement-dependent binding of C-reactive protein complexes to human erythrocyte CR1.

C. Mold, T. D. Du Clos, C. Gurule, 1996, Clinical immunology and immunopathology.

Opsonic properties of C-reactive protein in vivo.

C. Mold, T. D. Du Clos, S. Nakayama, 1982, Journal of immunology.

PhagocytosisReceptors and Opsonizes Particles for g Serum Amyloid P Component Binds to Fc

D. Bharadwaj, C. Mold, T. W. Clos, 2001 .

Quantitative analysis of C4b dimer binding to distinct sites on the C3b/C4b receptor (CR1).

C. Mold, P. Ford, H. Marsh, 1994, The Journal of biological chemistry.

The Major Receptor for C-Reactive Protein on Leukocytes Is Fc (cid:103) Receptor II

D. Bharadwaj, C. Mold, M. Stein, 1999 .

Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis.

L. Marnell, C. Mold, K. D. Clos, 2005, The Journal of biological chemistry.

Serum Amyloid P Component and C-Reactive Protein Opsonize Apoptotic Cells for Phagocytosis through Fcγ Receptors

C. Mold, Rebecca Baca, T. W. Clos, 2002 .

Serum Amyloid P Component Binds to Fcγ Receptors and Opsonizes Particles for Phagocytosis1

C. Mold, T. D. Du Clos, Eric Markham, 2001, The Journal of Immunology.

Serum Amyloid P Component and C-Reactive Protein Mediate Phagocytosis Through Murine FcγRs1

C. Mold, T. D. Du Clos, H. Gresham, 2001, The Journal of Immunology.

C-reactive protein and the acute phase response.

M. Benson, C. Mold, H. Gewurz, 1981, Advances in internal medicine.

Serum amyloid P component binds to histones and activates the classical complement pathway.

C. Mold, T. D. Du Clos, P. Hicks, 1992, Journal of immunology.

Epstein-Barr virus regulates activation and processing of the third component of complement

G. Nemerow, C. Mold, B. Bradt, 1988, The Journal of experimental medicine.

Release of soluble immune complexes from immune adherence receptors on human erythrocytes is mediated by C3b inactivator independently of Beta 1H and is accompanied by generation of C3c.

C. Mold, G. Prince, M. Medof, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The Human Complement System

C. Mold, D. Hourcade, J. Atkinson, 2019, Clinical Immunology.

C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fcγ Receptors1

L. Marnell, C. Mold, T. D. Du Clos, 2007, The Journal of Immunology.

C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific.

D. Bharadwaj, C. Mold, T. D. Du Clos, 2000, The Journal of clinical investigation.

Structural recognition and functional activation of FcγR by innate pentraxins

Jinghua Lu, P. Sun, L. Marnell, 2008, Nature.

Effect of membrane phospholipids on activation of the alternative complement pathway.

C. Mold, 1989, Journal of immunology.

Role of complement in host defense against bacterial infection.

C. Mold, Carolyn Mold, 1999, Microbes and infection.

Complementary Recognition of Alternative Pathway Activators by Decay-Accelerating Factor and Factor H

C. Mold, Damian M. Kraus, D. Kraus, 1998, Infection and Immunity.

Activation of the alternative complement pathway by exposure of phosphatidylethanolamine and phosphatidylserine on erythrocytes from sickle cell disease patients.

C. Mold, G. Phillips, R. H. Wang, 1993, The Journal of clinical investigation.

20 – Complement and complement deficiencies

C. Mold, T. W. Clos, 2008 .

Cooperation Between Decay-Accelerating Factor and Membrane Cofactor Protein in Protecting Cells from Autologous Complement Attack1

C. Mold, J. Atkinson, W. Brodbeck, 2000, The Journal of Immunology.

Complement Attack Protecting Cells from Autologous Factor and Membrane Cofactor Protein in Cooperation Between Decay-Accelerating

C. Mold, J. Atkinson, W. Brodbeck, 2000 .

Structure/function studies of human decay‐accelerating factor

C. Mold, W. Brodbeck, L. Kuttner-Kondo, 2000, Immunology.

Localization of classical and alternative pathway regulatory activity within the decay-accelerating factor.

C. Mold, W. Brodbeck, M. Medof, 1996, Journal of immunology.

C-reactive protein

C. Mold, T. W. Clos, 2004, Immunologic research.

Protection from Streptococcus pneumoniae Infection by C-Reactive Protein and Natural Antibody Requires Complement But Not Fcγ Receptors1

C. Mold, T. D. Du Clos, B. Rodic-Polic, 2002, The Journal of Immunology.

Hamster female protein binding to chromatin, histones and DNA.

C. Mold, T. D. Du Clos, J. Coe, 1992, Molecular immunology.

Regulation of complement activation by C-reactive protein.

C. Mold, T. D. Du Clos, H. Gewurz, 1999, Immunopharmacology.

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes

V. Nussenzweig, C. Mold, K. Iida, 1982, The Journal of experimental medicine.

C-reactive protein inhibits plasmacytoid dendritic cell interferon responses to autoantibody immune complexes.

C. Mold, T. W. Clos, 2013, Arthritis and rheumatism.

Pentraxins and Fc receptors

Jinghua Lu, P. Sun, C. Mold, 2012, Immunological reviews.

Macrophages Activated by C-Reactive Protein through FcγRI Transfer Suppression of Immune Thrombocytopenia1

L. Marnell, C. Mold, T. D. Du Clos, 2009, The Journal of Immunology.

C-reactive protein at the interface between innate immunity and inflammation

L. Marnell, C. Mold, T. D. Du Clos, 2008, Expert review of clinical immunology.

Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein.

L. Marnell, C. Mold, T. D. Du Clos, 2006, Arthritis and rheumatism.

Reversal of ongoing proteinuria in autoimmune mice by treatment with C-reactive protein.

L. Marnell, C. Mold, T. D. Du Clos, 2005, Arthritis and rheumatism.

C-Reactive Protein Binding to Murine Leukocytes Requires Fcγ Receptors1

C. Mold, T. D. Du Clos, M. Stein, 2000, The Journal of Immunology.

C-reactive protein binds to Fc gamma RI in transfected COS cells.

L. Marnell, C. Mold, T. D. Du Clos, 1995, Journal of immunology.

C-Reactive Protein Enhances Immunity to Streptococcus pneumoniae by Targeting Uptake to FcγR on Dendritic Cells1

C. Snapper, C. Mold, T. D. Du Clos, 2007, The Journal of Immunology.

C-Reactive Protein Increases Cytokine Responses to Streptococcus pneumoniae through Interactions with Fcγ Receptors1

C. Mold, T. D. Du Clos, 2006, The Journal of Immunology.

Pentraxins (CRP, SAP) in the process of complement activation and clearance of apoptotic bodies through Fcγ receptors

C. Mold, T. D. Du Clos, Terry W Du Clos, 2011, Current opinion in organ transplantation.

Analysis of Binding Sites in Human C-reactive Protein for FcγRI, FcγRIIA, and C1q by Site-directed Mutagenesis*

L. Marnell, C. Mold, K. D. Clos, 2005, Journal of Biological Chemistry.

Complement activation during painful crisis in sickle cell anemia.

C. Mold, G. Phillips, J. Tamerius, 1995, Clinical immunology and immunopathology.

C-reactive protein binding to murine leukocytes requires Fc gamma receptors.

C. Mold, T. D. Du Clos, M. Stein, 2000, Journal of immunology.

The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II

D. Bharadwaj, C. Mold, M. Stein, 1999 .

Recurrent bacterial infections associated with C3 nephritic factor and hypocomplementemia.

K. Edwards, C. Mold, H. Gewurz, 1983, The New England journal of medicine.

C3 nephritic factor protects bound C3bBb from cleavage by factor I and human erythrocytes.

C. Mold, M. Medof, 1985, Molecular immunology.

Cooperation between decay accelerating factor and membrane cofactor protein in protecting cells from autologous complement attack

C. Mold, J. Atkinson, W. Brodbeck, 2000 .

Pentraxins and Fc Receptor-Mediated Immune Responses

Jinghua Lu, P. Sun, C. Mold, 2018, Front. Immunol..

C-reactive protein inhibits pneumococcal activation of the alternative pathway by increasing the interaction between factor H and C3b.

C. Mold, H. Gewurz, M. Kingzette, 1984, Journal of immunology.

A common site within factor H SCR 7 responsible for binding heparin, C‐reactive protein and streptococcal M protein

S. Ranganathan, C. Mold, V. Fischetti, 2003 .

A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein.

S. Ranganathan, C. Mold, V. Fischetti, 2000, European journal of immunology.

Growth of group B streptococci in human serum leads to increased cell surface sialic acid and decreased activation of the alternative complement pathway.

C. Mold, N. Correa, M. Platt, 1994, Canadian journal of microbiology.

C-reactive protein receptors on the human monocytic cell line U-937. Evidence for additional binding to Fc gamma RI.

R. Crowell, C. Mold, T. D. Du Clos, 1991, Journal of immunology.

The Role of C-reactive Protein in the Resolution of Bacterial Infection *

C. Mold, T. D. Du Clos, 2001, Current opinion in infectious diseases.

C‐REACTIVE PROTEIN REACTIVITY WITH COMPLEMENT AND EFFECTS ON PHAGOCYTOSIS *

K. Edwards, C. Mold, T. D. Du Clos, 1982, Annals of the New York Academy of Sciences.

Monocyte deactivation correlates with injury severity score, but not with heme oxygenase-1 levels in trauma patients.

C. Mold, S. West, 2011, The Journal of surgical research.

This information is current as Receptors γ Leukocytes Requires Fc C-Reactive Protein Binding to Murine

C. Mold, M. Stein, T. W. Clos, 2000 .

An Fc&ggr;RIIa polymorphism with decreased C-reactive protein binding is associated with sepsis and decreased monocyte HLA-DR expression in trauma patients

C. Mold, O. Myers, S. West, 2015, The journal of trauma and acute care surgery.

C-Reactive Protein Mediates Protection from Lipopolysaccharide Through Interactions With FcγR1

C. Mold, T. D. Du Clos, Wilfredo Rodriguez, 2002, The Journal of Immunology.

Decreased autoantibody levels and enhanced survival of (NZB x NZW) F1 mice treated with C-reactive protein.

C. Mold, T. D. Du Clos, L. Zlock, 1994, Clinical immunology and immunopathology.

C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R.

C. Mold, T. D. Du Clos, Wilfredo Rodriguez, 2002, Journal of immunology.

The role of C‐reactive protein and polyarginine in tumor immunotherapy

C. Mold, D. Roseman, M. Haklin, 1986, Cancer.

Sublytic complement attack exposes C-reactive protein binding sites on cell membranes.

C. Mold, T. D. Du Clos, Y. P. Li, 1994, Journal of immunology.

The major receptor for c-reactive protein on leukocytes FcyII

D. Bharadwaj, C. Mold, M. Stein, 1999 .

Recognition and functional activation of the human IgA receptor (FcαRI) by C-reactive protein

Jinghua Lu, P. Sun, L. Marnell, 2011, Proceedings of the National Academy of Sciences.

Binding of human C-reactive protein to bacteria

C. Mold, H. Gewurz, R. L. Kaplan, 1982, Infection and immunity.

Binding of C-reactive protein to nucleated cells leads to complement activation without cytolysis.

C. Mold, H. Gewurz, S. Berman, 1986, Journal of immunology.

Cellular Responses to the Membrane Attack Complex

C. Mold, 1998 .

Activation of the alternative complement pathway by EBV and the viral envelope glycoprotein, gp350.

G. Nemerow, C. Mold, B. Bradt, 1988, Journal of Immunology.

Multiple ligand binding sites on domain seven of human complement factor H.

S. Ranganathan, C. Mold, T. Jokiranta, 2001, International immunopharmacology.

Localization of C-reactive protein in inflammatory lesions of experimental allergic encephalomyelitis.

J. Alroy, C. Mold, T. D. Du Clos, 1981, Clinical and experimental immunology.

C-reactive protein increases cytokine responses to Streptococcus pneumoniae through interactions with Fc gamma receptors.

C. Mold, T. D. Du Clos, 2006, Journal of immunology.

Effect of C-reactive protein on the complement-mediated stimulated of human neutrophils by Streptococcus pneumoniae serotypes 3 and 6

K. Edwards, C. Mold, H. Gewurz, 1982, Infection and immunity.

Inhibition of antibody responses to phosphocholine by C-reactive protein.

C. Mold, T. D. Du Clos, S. Nakayama, 1984, Journal of immunology.

R on Dendritic Cells γ Uptake to Fc by Targeting Streptococcus pneumoniae C-Reactive Protein Enhances Immunity to Snapper and Carolyn Mold

C. Snapper, C. Mold, T. W. Clos, 2007 .

CR2 is a complement activator and the covalent binding site for C3 during alternative pathway activation by Raji cells.

G. Nemerow, C. Mold, B. Bradt, 1988, Journal of immunology.

C-Reactive Protein Increases Cytokine Responses to Streptococcus pneumoniae through Interactions with Fc Receptors 1

C. Mold, T. W. Clos, 2006 .

C-Reactive Protein as a Regulator of Autoimmune Disease

C. Mold, T. W. Clos, 2005 .

Pentraxins and IgA share a binding hot‐spot on FcαRI

Jinghua Lu, P. Sun, L. Marnell, 2014, Protein science : a publication of the Protein Society.

Requirement for human red blood cells in inactivation of C3b in immune complexes and enhancement of binding to spleen cells.

C. Mold, T. Lam, G. Prince, 1983, Journal of immunology.

A role for C-reactive protein in the complement-mediated stimulation of human neutrophils by type 27 Streptococcus pneumoniae.

T. Lint, K. Edwards, C. Mold, 1982, Journal of immunology.

Regulation of complement by direct binding of factor H to C-reactive protein

C. Mold, M. Stein, T. W. Clos, 1998 .

Inhibitory effect of C-reactive protein on alternative C pathway activation by liposomes and Streptococcus pneumoniae.

C. Mold, H. Gewurz, 1981, Journal of immunology.

Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation

C. Mold, C. Morris, 2001, Immunology.

20 – Complement in host deficiencies and diseases

C. Mold, T. W. Clos, 2013 .

Mechanism of complement‐dependent haemolysis via the lectin pathway: role of the complement regulatory proteins

Mold, Zhang, Lint, 1999, Clinical and experimental immunology.

C-reactive protein and the acute phase response.

C. Mold, H. Gewurz, I. Kushner, 1982, Advances in internal medicine.

Interaction of C-reactive protein with liposomes. III. Membrane requirements for binding.

C. Mold, H. Gewurz, C. Alving, 1981, Journal of immunology.

Inflammatory potential of C-reactive protein complexes compared to immune complexes.

C. Mold, T. D. Du Clos, C. Morris, 1998, Clinical immunology and immunopathology.

With Fc Lipopolysaccharide Through Interactions C-Reactive Protein Mediates Protection from

C. Mold, T. D. Clos, Wilfredo Rodriguez, 2013 .

Identification of a polypeptide sequence that mediates nuclear localization of the acute phase protein C-reactive protein.

C. Mold, T. D. Du Clos, R. F. Stump, 1990, Journal of immunology.