Z. Shakked

发表

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs

B. Honig, R. Rohs, M. Kitayner, 2010, Nature Structural &Molecular Biology.

Structural basis of DNA recognition by p53 tetramers.

M. Kitayner, H. Rozenberg, D. Rabinovich, 2006, Molecular cell.

Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.

V. Rotter, R. Brosh, H. Rozenberg, 2009, Journal of molecular biology.

29 Structural and binding properties of DNA response elements bound to p53 proteins and the role of spacer sequences in p53-DNA interactions

D. Crothers, M. Kitayner, Z. Shakked, 2015, Journal of biomolecular structure & dynamics.

Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein–DNA interactions

Remo Rohs, R. Rohs, H. Rozenberg, 2013, Nucleic acids research.

A-form conformational motifs in ligand-bound DNA structures.

W. Olson, Xiang-Jun Lu, Z. Shakked, 2000, Journal of molecular biology.

DNA binding and 3′–5′ exonuclease activity in the murine alternatively-spliced p53 protein

V. Rotter, Z. Shakked, N. Kessler, 2002, Oncogene.

Structural and energetic origins of sequence-specific DNA bending: Monte Carlo simulations of papillomavirus E2-DNA binding sites.

R. Rohs, Z. Shakked, H. Sklenar, 2005, Structure.

Local DNA stretching mimics the distortion caused by the TATA box-binding protein.

R Lavery, R. Lavery, Z. Shakked, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Determinants of repressor/operator recognition from the structure of the trp operator binding site

A. Joachimiak, P. Sigler, D. Rabinovich, 1994, Nature.

The crystal structure of d(CCCCGGGG): a new A-form variant with an extended backbone conformation.

A. Rich, A. Wang, Z. Shakked, 1987, Journal of biomolecular structure & dynamics.

Ordered water structure in an A-DNA octamer at 1.7 A resolution.

T. Prangé, O. Kennard, D. Rabinovich, 1986, Journal of biomolecular structure & dynamics.

RUN-CBFβ Interaction in C. elegans: Computational Prediction and Experimental Verification

E. Eyal, O. Suad, Z. Shakked, 2007 .

Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 Å resolution

Y. Peleg, S. Albeck, N. Elad, 2018, Nature Communications.

Molecular replacement: the revival of the molecular Fourier transform method.

D. Rabinovich, Z. Shakked, H. Rozenberg, 1998, Acta crystallographica. Section D, Biological crystallography.

24(R), 25-dihydroxyvitamin D2 synthesis, determination of absolute configuration by x-ray analysis and identification as a kidney metabolite of vitamin D2

D. Rabinovich, Z. Shakked, F. Frolow, 1979 .

Proton nuclear Overhauser effect study of the structure of a deoxyoligonucleotide duplex in aqueous solution.

Z. Shakked, D. Williams, D. Reid, 1983, Biochemistry.

Isolation and identification of 24,25-dihydroxy vitamin D2 by use of the perfused rat kidney

D. Rabinovich, Z. Shakked, F. Frolow, 1979 .

Sequence-dependent effects in A-DNA double helices

Z. Shakked, T. Haran, 1988 .

Structural Basis of DNA Recognition by p53 Tetramers (complex III)

M. Kitayner, H. Rozenberg, D. Rabinovich, 2006 .

Interactions of tris buffer with nucleotides: the crystal structure of tris(hydroxymethyl)methylammonium adenosine 5'-diphosphate dihydrate.

Z. Shakked, M. Viswamitra, T. P. Singh, 1980, Biochemistry.

Predicting indirect readout effects in protein-DNA interactions.

Yongli Zhang, D. Crothers, Z. Shakked, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Molecular flexibility in ab initio drug docking to DNA: binding-site and binding-mode transitions in all-atom Monte Carlo simulations

Remo Rohs, Heinz Sklenar, R. Rohs, 2005, Nucleic acids research.

Optical induction in chiral crystals. I. The crystal and molecular structures of 4,4'‐dimethylchalcone

D. Rabinovich, Z. Shakked, 1974 .

X-ray study of the rubidium salt of ADP

Z. Shakked, M. Viswamitra, M. Hosur, 1976, Nature.

A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein.

A Klug, O Kennard, T. Steitz, 1979, Journal of molecular biology.

A standard reference frame for the description of nucleic acid base-pair geometry.

H M Berman, M Gerstein, S Neidle, 2001, Journal of molecular biology.

X-ray and solution studies of DNA oligomers and implications for the structural basis of A-tract-dependent curvature.

M Eisenstein, M. Eisenstein, B. Luisi, 1997, Journal of molecular biology.

DNA bending by an adenine–thymine tract and its role in gene regulation

H. Rozenberg, D. Rabinovich, Z. Shakked, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Examination of intramolecular potential surfaces of flexible conjugated molecules by calculation of crystal structures. equilibrium geometries of chalc

A. Warshel, E. Huler, D. Rabinovich, 1974 .

On the potential role of the amino nitrogen atom as a hydrogen bond acceptor in macromolecules.

F. J. Luque, J. Šponer, M. Orozco, 1998, Journal of molecular biology.

DNA double helical fragment at atomic resolution

S. A. Salisbury, G. Sheldrick, Z. Shakked, 1978, Nature.

New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.

H. Rozenberg, Z. Shakked, T. Haran, 2018, Structure.

Structure of the deoxytetranucleotide d‐pApTpApT and a sequence‐dependent model for poly(dA‐dT)

S. A. Salisbury, G. Sheldrick, Z. Shakked, 1982, Biopolymers.

The conformation of the DNA double helix in the crystal is dependent on its environment

M. Eisenstein, D. Rabinovich, Z. Shakked, 1989, Nature.

Structures of the mismatched duplex d(GGGTGCCC) and one of its Watson-Crick analogues d(GGGCGCCC).

M. Eisenstein, D. Rabinovich, Z. Shakked, 1988, Journal of molecular biology.

Sequence-dependent conformation of an A-DNA double helix. The crystal structure of the octamer d(G-G-T-A-T-A-C-C).

S. A. Salisbury, D. Rabinovich, Z. Shakked, 1983, Journal of molecular biology.

Crystalline A-DNA: the X-ray analysis of the fragment d(G-G-T-A-T-A-C-C)

S. A. Salisbury, D. Rabinovich, Z. Shakked, 1981, Proceedings of the Royal Society of London. Series B. Biological Sciences.

The effect of the base sequence on the fine structure of the DNA double helix.

D. Rabinovich, Z. Shakked, 1986, Progress in biophysics and molecular biology.

Diverse p53/DNA binding modes expand the repertoire of p53 response elements

V. Rotter, Z. Shakked, N. Kessler, 2017, Proceedings of the National Academy of Sciences.

Structural studies of p 53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein – DNA interactions

R. Rohs, H. Rozenberg, Z. Shakked, 2013 .

DNA recognition by the RUNX1 transcription factor is mediated by an allosteric transition in the RUNT domain and by DNA bending.

D. Rabinovich, Z. Shakked, L. Shimon, 2002, Structure.

Structures of the DNA-binding site of Runt-domain transcription regulators.

M. Kitayner, H. Rozenberg, D. Rabinovich, 2005, Acta crystallographica. Section D, Biological crystallography.

Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli

Y. Peleg, S. Albeck, N. Elad, 2018, bioRxiv.

Expression of a recombinant, 4’-Phosphopantetheinylated, active M. tuberculosis Fatty acid Synthase I in E. coli

Y. Peleg, S. Albeck, N. Elad, 2018, bioRxiv.

Post-translational regulation of p53 function through 20S proteasome-mediated cleavage

V. Rotter, H. Solomon, N. Goldfinger, 2017, Cell Death and Differentiation.

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3)

H. Rozenberg, O. Suad, Z. Shakked, 2010 .

AcpM, the meromycolate extension acyl carrier protein of Mycobacterium tuberculosis, is activated by the 4'-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.

Y. Peleg, O. Dym, S. Albeck, 2015, Biochemistry.

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ)

L. Abrahmsén, H. Rozenberg, Z. Shakked, 2021, Nature Communications.

A new approach to structure determination of large molecules by multi-dimensional search methods

D. Rabinovich, Z. Shakked, Z. Shakked, 1984 .

Left-handed DNA crossovers. Implications for DNA-DNA recognition and structural alterations.

Z. Shakked, Y. Timsit, M. Shatzky-Schwartz, 1999, Journal of biomolecular structure & dynamics.

The influence of the environment on DNA structures determined by X-ray crystallography

Z. Shakked, 1991 .

The structure and hydration of the A-DNA fragment d(GGGTACCC) at room temperature and low temperature.

M. Eisenstein, D. Rabinovich, Z. Shakked, 2011, Nucleic acids research.

Structural code for DNA recognition revealed in crystal structures of papillomavirus E2-DNA targets.

H. Rozenberg, D. Rabinovich, Z. Shakked, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A novel form of the DNA double helix imposed on the TATA-box by the TATA-binding protein

Z. Shakked, Zippora Shakked, Gali Guzikevich-Guerstein, 1996, Nature Structural Biology.

Hydration patterns and intermolecular interactions in A-DNA crystal structures. Implications for DNA recognition.

M. Eisenstein, Z. Shakked, Miriam Eisenstein, 1995, Journal of molecular biology.

Base-stacking interactions in double-helical DNA structures: experiment versus theory.

Z. Shakked, T. Haran, Z. Berkovich-Yellin, 1984, Journal of biomolecular structure & dynamics.

Crystal Structure Studies on DNA Oligomers

S. A. Salisbury, Z. Shakked, M. Viswamitra, 1983 .

The crystal and molecular structure of 3-methyl-mono-o-benzylautumnaline

Z. Shakked, T. P. Singh, 1977 .

Low-temperature study of the A-DNA fragment d(GGGCGCCC).

M. Eisenstein, D. Rabinovich, Z. Shakked, 1988, Acta crystallographica. Section B, Structural science.

61 High-resolution crystal structures of p53 mutants and their interaction with DNA

H. Rozenberg, Z. Shakked, Y. Diskin‐Posner, 2013 .

Quaternary structure of p53: The light at the end of the tunnel

Z. Shakked, 2007, Proceedings of the National Academy of Sciences.

Anomalous DNA binding by E2 regulatory protein driven by spacer sequence TATA

D. Crothers, Z. Shakked, R. Hegde, 2010, Nucleic acids research.

Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 Å resolution

Y. Peleg, S. Albeck, N. Elad, 2018, Nature Communications.

Crystallographic studies of dehydrohalogenation in solid meso-dibromobutane derivatives. II. The crystal and molecular structures of meso-β,β'-dibromoadiponitrile (I), meso-(RSRS)-α,α'-dimethyl-β,β'-dibromoadiponitrile (II) and meso-(RRSS)-α,α'-dimethyl-β,β'-dibromoadiponitrile (III)

D. Rabinovich, Z. Shakked, 1978 .

Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.

Y. Peleg, O. Dym, S. Albeck, 2009, Journal of molecular biology.

RUN-CBFbeta interaction in C. elegans: computational prediction and experimental verification.

E. Eyal, O. Suad, Z. Shakked, 2007, Journal of Biomolecular Structure and Dynamics.