K. Hartmuth

发表

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

H. Urlaub, Cyrille Girard, C. Will, 2012, Nature Communications.

GraFix: sample preparation for single-particle electron cryomicroscopy

Henning Urlaub, Bjoern Sander, Franz Herzog, 2008, Nature Methods.

RNA structure and RNA-protein interactions in purified yeast U6 snRNPs.

H. Urlaub, K. Hartmuth, R. Lührmann, 2006, Journal of molecular biology.

Polymerase Chain-Reaction (PCR) Detection of Rhinoviruses

K. Hartmuth, H. Kovar, H. Auer, 1992 .

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

M. Wilm, H. Urlaub, C. Will, 2002, Proceedings of the National Academy of Sciences of the United States of America.

LÜHRMANN for spliceosomal E-complex formation end of human U 2 snRNA are required ′ Modified nucleotides at the 5

K. Hartmuth, R. Lührmann, 2004 .

Modified nucleotides at the 5' end of human U2 snRNA are required for spliceosomal E-complex formation.

K. Hartmuth, R. Lührmann, Gizem Dönmez, 2004, RNA.

RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core

Zhichao Miao, E. Westhof, K. Hartmuth, 2013, The EMBO journal.

Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex

H. Stark, H. Urlaub, B. Kastner, 2018, Cell.

Molecular architecture of the human 17S U2 snRNP

H. Stark, H. Urlaub, C. Will, 2020, Nature.

Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.

I. Maurer-Fogy, J. Smolen, K. Hartmuth, 1992, The Journal of clinical investigation.

Demonstration of a new antinuclear antibody (anti-RA33) that is highly specific for rheumatoid arthritis.

G. Kolarz, J. Smolen, K. Hartmuth, 1989, Arthritis and rheumatism.

Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex

H. Stark, H. Urlaub, B. Kastner, 2018, Cell.

The Preparation of HeLa Cell Nuclear Extracts

B. Kastner, K. Hartmuth, R. Lührmann, 2012 .

Binding of the Human Prp31 Nop Domain to a Composite RNA-Protein Platform in U4 snRNP

Ping Li, Teresa Carlomagno, Olexandr Dybkov, 2007, Science.

Functional interaction of a novel 15.5kD[U4/U6·U5] tri‐snRNP protein with the5′ stem–loop of U4 snRNA

H. Urlaub, K. Hartmuth, R. Lührmann, 1999, The EMBO journal.

Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner

B. Kastner, K. Hartmuth, R. Lührmann, 1999, Molecular and Cellular Biology.

Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP.

C. Will, K. Hartmuth, R. Lührmann, 2006, RNA.

the absence of a penta-snRNP Functional spliceosomal A complexes can be assembled in vitro in

C. Will, K. Hartmuth, R. Lührmann, 2006 .

Purification of two picornaviral 2A proteinases: interaction with eIF-4 gamma and influence on in vitro translation.

K. Hartmuth, W. Sommergruber, H. Klump, 1993, Biochemistry.

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome

H. Urlaub, K. Hartmuth, R. Lührmann, 2008, Nature Structural &Molecular Biology.

Unusual branch point selection in processing of human growth hormone pre-mRNA

K. Hartmuth, K Hartmuth, A Barta, 1988, Molecular and cellular biology.

The expression of a nopaline synthase — human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue

Andrea Barta, K. Hartmuth, A. Barta, 1986, Plant Molecular Biology.

Analysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry.

H. Urlaub, K. Hartmuth, R. Luhrmann, 2003, RNA.

A General Approach for Identification of RNA-Protein Cross-linking Sites within Native Human Spliceosomal Small Nuclear Ribonucleoproteins (snRNPs)

S. Kostka, H. Urlaub, K. Hartmuth, 2000, The Journal of Biological Chemistry.

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

H. Stark, H. Urlaub, C. Will, 2017, Nature.

In vitro processing of a plant pre-mRNA in a HeLa cell nuclear extract.

K. Hartmuth, A. Barta, 1986, Nucleic acids research.

Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment.

K. Hartmuth, R. Lührmann, R. Ficner, 2000, Molecular cell.

Composition and three‐dimensional EM structure of double affinity‐purified, human prespliceosomal A complexes

Henning Urlaub, Bjoern Sander, Monika M Golas, 2007, The EMBO journal.

U2 snRNA-Protein Contacts in Purified Human 17S U2 snRNPs and in Spliceosomal A and B Complexes

C. Will, K. Hartmuth, R. Lührmann, 2006, Molecular and Cellular Biology.

Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.

H. Stark, H. Urlaub, C. Will, 2020, Molecular cell.

Molecular architecture of the Saccharomyces cerevisiae activated spliceosome

Henning Urlaub, Reinhard Rauhut, Ashwin Chari, 2016, Science.

Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions

Henning Urlaub, Holger Stark, Daniel Boehringer, 2006, Molecular and Cellular Biology.

Tobramycin affinity tag purification of spliceosomes.

K. Hartmuth, R. Lührmann, H. Vornlocher, 2004, Methods in molecular biology.

Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes

K. Hartmuth, R. Lührmann, J. Schmitzová, 2015, PLoS genetics.

Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes

E. Westhof, K. Hartmuth, R. Lührmann, 2006, The EMBO journal.

Assembly and isolation of spliceosomal complexes In Vitro.

K. Hartmuth, R. Lührmann, P. Odenwaelder, 2012 .

Multiple RNA–RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome

C. Will, K. Hartmuth, R. Lührmann, 2018, Nucleic acids research.

Yeast Prp2 liberates the 5′ splice site and the branch site adenosine for catalysis of pre-mRNA splicing

K. Hartmuth, R. Lührmann, C. Höbartner, 2017, RNA.

The 5' end of U2 snRNA is in close proximity to U1 and functional sites of the pre-mRNA in early spliceosomal complexes.

C. Will, B. Kastner, K. Hartmuth, 2007, Molecular cell.

RNA Structural Requirements for the Association of the Spliceosomal hPrp31 Protein with the U4 and U4atac Small Nuclear Ribonucleoproteins*

K. Hartmuth, R. Lührmann, S. Nottrott, 2006, Journal of Biological Chemistry.

Spliceosomal A and B Complexes Human 17 S U 2 snRNPs and in U 2 snRNA-Protein Contacts in Purified

Nastaran, C. Will, K. Hartmuth, 2006 .

An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles.

K. Hartmuth, R. Lührmann, J. Huber, 1999, Journal of molecular biology.

A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles.

H. Urlaub, K. Hartmuth, R. Lührmann, 2002, Methods.

Unusual Branch Point Selection inProcessing ofHumanGrowth

K. Hartmuth, A. Barta, 2011 .

In vitro processing of the human growth hormone primary transcript.

K. Hartmuth, A. Barta, 1987, Nucleic acids research.