D. Hughes

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Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells

M. Rathbone, P. Middlemiss, J-K Kim, 1992, Neuroscience Research.

The biosynthesis of pramanicin in Stagonospora sp. ATCC 74235: a modified acyltetramic acid

D. Hughes, P. H. Harrison, P. Duspara, 2000 .

Sampling the Antibiotic Resistome

D. Hughes, Gerard D. Wright, Vanessa M D'Costa, 2006, Science.

Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis.

T. Mukhtar, G. Wright, D. Hughes, 2001, Biochemistry.

Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.

Abdellah Allali-Hassani, Razvan Nutiu, Nadine H Elowe, 2006, Angewandte Chemie.

Bacterial species selective toxicity of two isomeric α/β-peptides: Role of membrane lipids

S. Gellman, D. Hughes, R. Epand, 2005 .

1H-nuclear magnetic resonance of intercalators and rGCA: a potential mutagenicity probe.

T. Neilson, D. Hughes, J. Coddington, 1984, Chemico-biological interactions.

Contribution of a G·U base pair to the stability of a short RNA helix

T. Neilson, D. Hughes, R. Bell, 1979 .

Influence of ether linkage on the lamellar to hexagonal phase transition of ethanolamine phospholipids.

C. Deber, D. Hughes, J. Boggs, 1981, Biochemistry.

Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB.

D. Hughes, M. Morar, K. Bhullar, 2009, Structure.

The solid phase synthesis and NMR spectroscopy of a 99Tc chelate–bombesin derived peptide conjugate

D. Hughes, J. Valliant, J. Thornback, 2001 .

Stabilizing effect of dangling bases on a short RNA double helix as determined by proton nuclear magnetic resonance spectroscopy

T. Neilson, D. Hughes, R. Bell, 1978 .

Structural studies on the polysaccharide portion of "A-band" lipopolysaccharide from a mutant (AK1401) of Pseudomonas aeruginosa strain PAO1

D. Hughes, A. Kropinski, J. Lam, 1991 .

Phosphatidylcholine structure determines cholesterol solubility and lipid polymorphism.

E. Wachtel, D. Hughes, R. Epand, 2005, Chemistry and physics of lipids.

Novel properties of cholesterol-dioleoylphosphatidylcholine mixtures.

E. Wachtel, D. Hughes, R. Epand, 2003, Biochimica et biophysica acta.

ApoA-I Mimetic Peptides with Differing Ability to Inhibit Atherosclerosis Also Exhibit Differences in Their Interactions with Membrane Bilayers*

A. D. Bain, D. Hughes, R. Epand, 2007, Journal of Biological Chemistry.

The Wall Teichoic Acid Polymerase TagF Efficiently Synthesizes Poly(glycerol phosphate) on the TagB Product Lipid III

E. Brown, D. Hughes, Gerard D. Wright, 2008, Chembiochem : a European journal of chemical biology.

Synthesis of 2- and 3-fluorotyrosine with dilute fluorine gas

D. Hughes, R. Chirakal, G. Firnau, 1987 .

Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide charges.

H. Mantsch, D. Hughes, R. Epand, 1989, The Journal of biological chemistry.

Application of relayed coherence transfer two‐dimensional nuclear magnetic resonance spectroscopy to the assignment of 1H chemical shifts in steroids

D. Hughes, 1988 .

Parameters for the calculation of proton NMR chemical shifts of oligoribonucleotides.

T. Neilson, D. Hughes, J. Coddington, 1985, Journal of biomolecular structure & dynamics.

A pulse sequence which provides rapid, routine 1H13C shift-correlated spectra

W. Reynolds, D. Hughes, R. Enríquez, 1985 .

A pulse sequence for establishing carbon-carbon connectivities via indirect 13C-1H polarization transfer modulated by vicinal 1H-1H coupling

W. Reynolds, D. Hughes, Marion Perpick-Dumont, 1985 .

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1

D. Hughes, J. Nodwell, Gerard D. Wright, 2010, The Journal of Antibiotics.

Properties of polyunsaturated phosphatidylcholine membranes in the presence and absence of cholesterol

A. D. Bain, D. Hughes, R. Epand, 2004, Magnetic resonance in chemistry : MRC.

Trindane−Ruthenium Sandwich Complexes: An NMR and X-ray Crystallographic Study of [(trindane)RuCl2]2, (trindane)RuCl2[P(OMe)3], and [(trindane)2Ru][BF4]2

D. Hughes, M. McGlinchey, H. Gupta, 1997 .

Stereochemistry of reduction by the 5α-reductase enzyme of Penicillium decumbens and the 1H NMR assignment of 5α-dihydrotestosterone

D. Hughes, H. Holland, Weili Xu, 1989 .

NMR analysis of fluorinated corticosteroids related to fluocinonide: Detection of long‐range 1H–19F couplings using the heteronuclear equivalent of the COSY experiment

A. D. Bain, D. Hughes, V. Robinson, 1991 .

Synthesis, spectroscopic and electrochemical properties of mononuclear and dinuclear bis(bipy)ruthenium(II) complexes containing dimethoxyphenyl(pyridin-2-yl)-1,2,4-triazole ligands

M. Maestri, D. Hughes, W. Browne, 2002 .

13C magnetic resonance spectra of some isoquinoline alkaloids and related model compounds

D. Hughes, D. Maclean, H. Holland, 1976 .

13C nuclear magnetic resonance spectra of the spirobenzylisoquinoline alkaloids and related model compounds

D. Hughes, D. Maclean, H. Holland, 1977 .

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor.

D. Hughes, M. Buttner, M. Naldrett, 2010, Nature chemical biology.

Rhodium complexes of 3,4-di(β-naphthyl)-2,5-diarylcyclopentadienone: indirect detection of slowed naphthyl rotation

A. D. Bain, D. Hughes, J. Britten, 2002 .

The Fluxional Character of (η5-C5H5)Fe(CO)2(η1-C9H7): Evidence for the [4 + 2] Cycloaddition of a Metal-Substituted Isoindene with Tetracyanoethylene

A. D. Bain, M. Brook, D. Hughes, 1997 .

Multidimensional NMR Study of Tris(indenyl)methylsilane: Molecular Dynamics Mapped onto a Hypercube

A. D. Bain, M. Brook, D. Hughes, 1996 .

Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals

D. Hughes, A. Vessières, G. Jaouen, 1995 .

Nickel(II) binding to glycylglycyl-L-tyrosine-N-methyl amide, a peptide mimicking the NH2-terminal nickel(II)-binding site of dog serum albumin: a 1H- and 13C-nuclear magnetic resonance investigation.

D. Hughes, J. Glennon, B. Sarkar, 1983, Journal of inorganic biochemistry.

Structure of 2-Methyl-1-(phenylethynyl)cyclopentanol and of Its Co2(CO)6 and (C5H5)2Mo2(CO)4 Cluster Complexes Co2(CO)6 as a Conformational Switch

K. Malisza, D. Hughes, L. Girard, 1995 .

Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr

Emma Griffiths, Kun Zhang, D. Hughes, 2008, Proceedings of the National Academy of Sciences.

Nearest‐neighbor and next‐nearest‐neighbor effects in the proton NMR spectra of the oligoribonucleotides ApGpX and CpApX

T. Neilson, D. Hughes, J. Everett, 1980, Biopolymers.

Studies of phospholipid hydration by high-resolution magic-angle spinning nuclear magnetic resonance.

D. Hughes, R. Epand, R. Stark, 1999, Biophysical journal.

Structures of zearalenone and zearalanone in solution: A high‐field NMR and molecular modelling study

D. Hughes, C. Cordier, G. Jaouen, 1990 .

Chapter 3 The 13C-Nmr Spectra of Isoquiinoline Alkaloids

D. Hughes, D. Maclean, 1981 .

Solidaline. A modified protoberberine alkaloid from Corydalissolida

D. Hughes, R. Manske, J. Saunders, 1978 .

The biosynthesis of pramanicin: origin of the carbon skeleton

D. Hughes, P. Harrison, R. W. Riddoch, 1998 .

Prediction of 1H NMR chemical shifts of DNA oligomers.

T. Neilson, D. Hughes, J. Coddington, 1983, Nucleic acids research.

TetX Is a Flavin-dependent Monooxygenase Conferring Resistance to Tetracycline Antibiotics*

D. Hughes, Gerard D. Wright, K. Koteva, 2004, Journal of Biological Chemistry.

Regiospecificity of aminoglycoside phosphotransferase from Enterococci and Staphylococci (APH(3')-IIIa).

G. Wright, D. Hughes, P. Thompson, 1996, Biochemistry.

Problems, artifacts and solutions in the INADEQUATE NMR experiment

Christopher Kumar Anand, A. D. Bain, D. Hughes, 2010, Magnetic resonance in chemistry : MRC.

An NMR study of the Lythraceae alkaloids

D. Hughes, Ian D. Spenser, Jerzy T. Wrobel, 2000 .

Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue.

G. Wright, D. Hughes, P. Thompson, 1996, Chemistry & biology.

NMR of the methylene group: Artifacts in the proton–proton decoupled heteronuclear two‐dimensional chemical shift correlation experiment

A. D. Bain, D. Hughes, H. Hunter, 1988 .

Binding of human normal and multiple sclerosis-derived myelin basic protein to phospholipid vesicles: effects on membrane head group and bilayer regions.

P. Fraser, C. Deber, D. Hughes, 1986, Archives of biochemistry and biophysics.

Purinergic stimulation of astroblast proliferation: Guanosine and its nucleotides stimulate cell division in chick astroblasts

M. Rathbone, P. Middlemiss, J-K Kim, 1991, Journal of neuroscience research.

Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci.

D. Daigle, G. Wright, D. Hughes, 1999, Chemistry & biology.

The COOH Terminus of Aminoglycoside Phosphotransferase (3′)-IIIa Is Critical for Antibiotic Recognition and Resistance*

A. Berghuis, D. Hughes, P. Thompson, 1999, The Journal of Biological Chemistry.

Inactivation of the Lipopeptide Antibiotic Daptomycin by Hydrolytic Mechanisms

T. Mukhtar, D. Hughes, Gerard D. Wright, 2011, Antimicrobial Agents and Chemotherapy.

Conformational studies on calcium binding by tBoc-Leu-Pro-Tyr-Ala-NHCH3, a tyrosine kinase substrate, in a nonpolar solvent.

A. D. Bain, V. Ananthanarayanan, D. Hughes, 1993, Journal of biomolecular structure & dynamics.

UDP-N-acetylmuramic acid (UDP-MurNAc) is a potent inhibitor of MurA (enolpyruvyl-UDP-GlcNAc synthase).

P. Berti, D. Hughes, S. Mizyed, 2005, Biochemistry.

Mimicking the membrane-mediated conformation of dynorphin A-(1-13)-peptide: circular dichroism and nuclear magnetic resonance studies in methanolic solution.

D. Hughes, R. Epand, C. Lancaster, 1991, Biochemistry.

Relative stability of guanosine-cytidine diribonucleotide cores: a 1H NMR assessment.

T. Neilson, D. Hughes, J. Coddington, 1984, Biochemistry.

A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region.

Debasis Mallik, Eric D Brown, E. Brown, 2006, Journal of medicinal chemistry.

Tigecycline is modified by the flavin-dependent monooxygenase TetX.

D. Hughes, Gerard D. Wright, I. Moore, 2005, Biochemistry.

The Apoptotic Protein tBid Promotes Leakage by Altering Membrane Curvature*

D. Hughes, J. Martinou, R. Epand, 2002, The Journal of Biological Chemistry.

Spectinomycin Kinase from Legionella pneumophila

G. Wright, D. Hughes, P. Thompson, 1998, The Journal of Biological Chemistry.

Two-step regio- and stereoselective syntheses of [19F]- and [18F]-2-deoxy-2-(R)-fluoro-beta-D-allose.

D. Hughes, R. Chirakal, G. Schrobilgen, 2006, Carbohydrate research.

15N NMR study of the ionization properties of the influenza virus fusion peptide in zwitterionic phospholipid dispersions.

D. Hughes, R. Epand, J. Macosko, 2000, Biophysical journal.

Chemical shift correlated two-dimensional nmr spectroscopy and its application to solving the proton nmr spectra of oligoribonucleotides

A. D. Bain, D. Hughes, J. Everett, 1980 .

Homonuclear and heteronuclear coupling in 5'-AMP as probed by two-dimensional proton nuclear magnetic resonance spectroscopy

A. D. Bain, D. Hughes, J. Everett, 1979 .

Effects of internal nonbonded bases and a G.U base pair on the stability of a short ribonucleic acid helix.

T. Neilson, D. Hughes, R. Bell, 1979, Biochemistry.

An NMR study of the Lycopodium alkaloids, annotinine and annotine: verification of the annotine structure

Robert V. Gerard, D. Hughes, D. Maclean, 1989 .

METHYLATED BASES STABILIZE SHORT RNA DUPLEXES

T. Neilson, D. Hughes, J. Coddington, 1983 .

Nearest‐neighbor and next‐nearest‐neighbor effects in the proton NMR spectra of the oligoribonucleotides ApXpG, CpXpG, CpApXpUpG, ApGpXpC, and ApGpXpCpU

T. Neilson, D. Hughes, J. Everett, 1981 .

Proton magnetic resonance studies on short duplexes. I. Helix formation by the duplex set GpApGpC:GpCpUpC

T. Neilson, D. Hughes, R. Bell, 1978 .

Proton magnetic resonance studies on short duplexes. II. The self-complementary oligoribonucleotide CpApUpG

T. Neilson, D. Hughes, R. Bell, 1978 .

Conformations of cyclic peptide/calcium complexes in solution

C. Deber, D. Hughes, 1982, Biopolymers.

The biosynthesis of pramanicin: intact incorporation of serine and absolute configuration of the antibiotic

D. Hughes, P. Duspara, P. Harrison, 1998 .

The Biosynthesis of Pramanicin: Intact Incorporation of Serine and Absolute Configuration of the Antibiotic.

D. Hughes, P. Duspara, P. Harrison, 1999 .

Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids.

S. Gellman, D. Hughes, R. Epand, 2005, Molecular membrane biology.

Mechanistic studies of the addition of carbonyl compounds to tetramesityldisilene and tetramesitylgermasilene

D. Hughes, M. S. Samuel, K. Baines, 2003 .