A. Freedman

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Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

Y. Tu, R. Dalla‐Favera, A. Califano, 2001, The Journal of experimental medicine.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Donna Neuberg, Steven M Kornblau, Johannes Köster, 2016, Cancer cell.

The Role of AKT and RAFTK in β1 Integrin Mediated Survival of Precursor B-acute Lymphoblastic Leukemia Cells

S. Sarkar, A. Freedman, M. Svoboda, 2002 .

Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma.

J. Winter, B. Djulbegovic, A. Freedman, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Natural history of mixed chimerism after bone marrow transplantation with CD6-depleted allogeneic marrow: a stable equilibrium.

K. Anderson, J. Ritz, A. Freedman, 1990, Blood.

Isolated human follicular dendritic cells display a unique antigenic phenotype

G. Freeman, A. Freedman, L. Nadler, 1989, The Journal of experimental medicine.

Increased Risk of Infectious Complications in Older Patients With Indolent Non-Hodgkin Lymphoma Exposed to Bendamustine

X. Gu, P. Nguyen, A. Freedman, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Safety, tolerability, and preliminary activity of IMGN529, a CD37-targeted antibody-drug conjugate, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: a dose-escalation, phase I study

I. Flinn, A. Freedman, A. Stathis, 2018, Investigational New Drugs.

A Phase II Study of Adjuvant Therapy with Anti-B 4-blocked Ricin after Autologous Bone Marrow Transplantation for Patients with Relapsed B-Cell Non-Hodgkin ’ s Lymphoma 1

J. Gribben, D. Neuberg, A. Freedman, 1999 .

A Phase II study of adjuvant therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with relapsed B-cell non-Hodgkin's lymphoma.

D. Neuberg, A. Freedman, S. O’Day, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer.

J. Armitage, P. Bierman, J. Vose, 1991, The New England journal of medicine.

Human bone marrow depleted of CD33-positive cells mediates delayed but durable reconstitution of hematopoiesis: clinical trial of MY9 monoclonal antibody-purged autografts for the treatment of acute myeloid leukemia.

K. Anderson, A. Freedman, J. Griffin, 1992, Blood.

Expression of mesenchyme‐specific gene signatures by follicular dendritic cells: insights from the meta‐analysis of microarray data from multiple mouse cell populations

T. Freeman, A. Freedman, D. S. Donaldson, 2011, Immunology.

Selective ablation of rat brain tumors by boron neutron capture therapy.

P. Rubin, A. Freedman, D. Gash, 1994, International journal of radiation oncology, biology, physics.

Autologous bone marrow transplantation therapy for multiple myeloma

K. Anderson, J. Ritz, A. Freedman, 1989, European journal of haematology. Supplementum.

Genetic Variation in DNA Repair Pathways and Risk of Non-Hodgkin's Lymphoma

C. Sander, B. Reva, Yevgeniy Antipin, 2014, PloS one.

Breast Lymphoma Associated With Breast Implants: Two Case-reports and a Review of the Literature

J. Friedberg, G. Pinkus, A. Weng, 2002, Leukemia & lymphoma.

Rethinking Prognosis and Therapy for Follicular Lymphoma.

A. Freedman, C. Jacobson, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hemolytic-uremic syndrome following bone marrow transplantation in adults for hematologic malignancies.

J. Gribben, D. Neuberg, K. Anderson, 1991, Blood.

90Y-Ibritumomab tiuxetan followed by reduced-intensity conditioning and allogeneic stem-cell transplantation in patients with advanced follicular lymphoma

A. LaCasce, A. Freedman, K. Stevenson, 2010, Bone Marrow Transplantation.

PD-1 Blockade with Pembrolizumab for Classical Hodgkin Lymphoma after Autologous Stem Cell Transplantation.

A. LaCasce, M. Shipp, J. Ritz, 2018, Blood.

Targeting the follicular lymphoma microenvironment through blockade of TNFα with etanercept

A. D. Van den Abbeele, J. Friedberg, D. Neuberg, 2008, Leukemia & lymphoma.

Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

D. Livingston, J. Decaprio, A. Freedman, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Is observation dead in follicular lymphoma? Still appropriate.

A. Freedman, C. Jacobson, 2015, Journal of the National Comprehensive Cancer Network : JNCCN.

Which patients with relapsed non-Hodgkin's lymphoma benefit from high-dose therapy and hematopoietic stem-cell transplantation?

A. Freedman, L. Nadler, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Effective purging of autologous hematopoietic stem cells using anti-B-cell monoclonal antibody-coated high-density microparticles prior to high-dose therapy for patients with non-Hodgkin's lymphoma.

J. Gribben, D. Neuberg, A. Freedman, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion

J. Ritz, A. Freedman, N. Spector, 1992 .

Hodgkin Disease Associated With T-Cell Non-Hodgkin Lymphomas

A. Weng, A. Freedman, Jennifer R. Brown, 2004 .

Hodgkin disease associated with T-cell non-Hodgkin lymphomas: case reports and review of the literature.

A. Weng, A. Freedman, Jennifer R. Brown, 2004, American journal of clinical pathology.

Prolonged disease-free survival after autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma with a poor prognosis.

K. Anderson, J. Ritz, B. Yeap, 1987, The New England journal of medicine.

Cell surface markers in hematologic malignancies.

A. Freedman, L. Nadler, L. Nadler, 1987, Seminars in oncology.

Rituximab/bendamustine and rituximab/cytarabine induction therapy for transplant-eligible mantle cell lymphoma.

A. LaCasce, A. Freedman, P. Armand, 2020, Blood advances.

A phase 2 study of Rituximab‐Bendamustine and Rituximab‐Cytarabine for transplant‐eligible patients with mantle cell lymphoma

A. LaCasce, M. Faham, L. Weng, 2016, British journal of haematology.

Early lymphoid lesions: conceptual, diagnostic and clinical challenges

E. Jaffe, S. Pittaluga, A. Freedman, 2014, Haematologica.

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

A. Freedman, T. Tedder, H. Levine, 1990, Journal of immunology.

Interleukin 6 gene expression in normal and neoplastic B cells.

G. Freeman, A. Freedman, L. Nadler, 1989, The Journal of clinical investigation.

The B cell surface molecule B1 is functionally linked with B cell activation and differentiation.

A. Freedman, A. Boyd, L. Nadler, 1985, Journal of immunology.

Expression of a novel 3.5-kb macrophage colony-stimulating factor transcript in human myeloma cells.

K. Anderson, G. Demetri, A. Freedman, 1989, Journal of Immunology.

An update on the role of high-dose therapy with autologous or allogeneic stem cell transplantation in mantle cell lymphoma

A. Freedman, E. Jacobsen, 2004, Current opinion in oncology.

Prevalence of familial malignancy in a prospectively screened cohort of patients with lymphoproliferative disorders

A. LaCasce, D. Neuberg, A. Freedman, 2008, British journal of haematology.

Pathobiology and treatment of Richter's transformation Author

A. Freedman, Jennifer R. Brown, R. Connor, 2010 .

Preexposure of resting B cells to interferon-gamma enhances their proliferative response to subsequent activation signals.

A. Freedman, J. Griffin, D. Fisher, 1987, Cellular immunology.

Functional Effects of TNF and Lymphotoxin α1β2 on FDC-like Cells

H. Husson, A. Freedman, J. Browning, 2000 .

Developments in purging in autotransplantation.

A. Freedman, L. Nadler, L. Nadler, 1993, Hematology/oncology clinics of North America.

Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-110.

G. Rice, J. Pober, A. Freedman, 1990, Science.

A. Freedman, H. Avraham, S. Avraham, 1997, The Journal of Biological Chemistry.

B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.

G. Freeman, A. Freedman, L. Nadler, 1989, Journal of immunology.

B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

J. Gribben, G. Freeman, A. Freedman, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Monoclonal antibody-purged autologous bone marrow transplantation in adults with acute lymphoblastic leukemia at high risk of relapse.

A. Freedman, R. Soiffer, R. Gonin, 1993, Bone marrow transplantation.

A chronic “postinfectious” fatigue syndrome associated with benign lymphoproliferation, B-cell proliferation, and active replication of human herpesvirus-6

M. Caligiuri, A. Komaroff, J. Ritz, 1990, Journal of Clinical Immunology.

Adhesion of follicular lymphoma cells to lymphoid germinal centers--a potential mechanism of tumor cell homing following autologous transplantation.

A. Freedman, C. Morimoto, L. Nadler, 1994, Leukemia & lymphoma.

Follicular non-Hodgkin's lymphoma cell adhesion to normal germinal centers and neoplastic follicles involves very late antigen-4 and vascular cell adhesion molecule-1.

A. Freedman, C. Morimoto, L. Nadler, 1992, Blood.

Expression and regulation of CD5 on in vitro activated human B cells

G. Freeman, A. Freedman, L. Nadler, 1989, European journal of immunology.

Is There a Best Initial Treatment for a New Patient With Low Grade Follicular Lymphoma

A. Freedman, C. Jacobson, 2016, Current Hematologic Malignancy Reports.

Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease.

J. Gribben, D. Neuberg, J. Aster, 1997, Blood.

All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment.

J. Gribben, G. Pinkus, G. Freeman, 1991, Blood.

Antibody and immunomodulatory agents in the treatment of indolent non-Hodgkin's lymphoma.

A. LaCasce, A. Freedman, 2008, Seminars in hematology.

Antibody and immunomodulatory agents in treatment of indolent non-Hodgkin's lymphoma

J. Friedberg, A. Freedman, 2006, Current treatment options in oncology.

Studies of in vitro activated CD5+ B cells.

G. Freeman, A. Freedman, L. Nadler, 1989, Blood.

Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells.

M. Belvin, A. Freedman, J. Griffin, 1991, Leukemia.

Endothelial cell lymphocyte function-associated antigen-3 and an unidentified ligand act in concert to provide costimulation to human peripheral blood CD4+ T cells.

J. Pober, A. Freedman, C. Hughes, 1991, Cellular immunology.

inducible gene expression, without significant toxicity - β / α interferon- rituximab in patients with non-Hodgkin lymphoma: increased Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and

J. Friedberg, R. Coffman, A. Freedman, 2013 .

In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease.

J. Gribben, J. Banchereau, J. Aster, 1994, Blood.

Regulation of Integrin-mediated p130Cas Tyrosine Phosphorylation in Human B Cells

B. Druker, A. Freedman, H. Hirai, 1997, The Journal of Biological Chemistry.

Phase II study of a TLR‐9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma

Derick R. Peterson, J. Friedberg, R. Fisher, 2009, British journal of haematology.

Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity.

J. Friedberg, R. Coffman, A. Freedman, 2005, Blood.

Mechanism of graft failure in HLA-matched and HLA-mismatched bone marrow transplant recipients.

J. Ritz, L. Bosserman, A. Freedman, 1989, Bone marrow transplantation.

Monoclonal antibodies: their use in bone marrow transplantation.

J. Ritz, A. Freedman, L. Nadler, 1987, Progress in hematology.

Hematology: ASCT in follicular lymphoma

A. Freedman, Jennifer R. Brown, 2009, Nature Reviews Clinical Oncology.

Predictive value of clonality assays in patients with non-Hodgkin's lymphoma undergoing autologous bone marrow transplant: a single institution study.

J. Gribben, D. Neuberg, D. Gilliland, 1998, Blood.

Cyclophosphamide, Doxorubicin, Vincristine, Prednisone Dose Intensification With Granulocyte Colony-Stimulating Factor Markedly Depletes Stem Cell Reserve for Autologous Bone Marrow Transplantation

J. Gribben, D. Neuberg, J. Ritz, 1997 .

Adjuvant immunotoxin therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with B-cell non-Hodgkin's lymphoma.

J. Gribben, J. Taylor, A. Freedman, 1993, Blood.

Pre-exposure of human B cells to recombinant IL-1 enhances subsequent proliferation.

G. Freeman, A. Freedman, L. Nadler, 1988, Journal of immunology.

Role of follicular dendritic cells in the regulation of B cell proliferation.

A. Freedman, S. Manié, D. Wang, 1995, Current topics in microbiology and immunology.

Follicular dendritic cells inhibit human B-lymphocyte proliferation.

A. Freedman, L. Nadler, J. Daley, 1992, Blood.

Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity.

L. Rassenti, T. Kipps, J. Ritz, 2016, Blood.

Normal cellular counterparts of B cell chronic lymphocytic leukemia.

F. Bieber, D. N. Levy, A. Freedman, 1987, Blood.

Immunologic heterogeneity of diffuse large cell lymphoma.

G. Pinkus, A. Freedman, D. Fisher, 1985, Blood.

Total lymphoid irradiation to prevent graft rejection in recipients of HLA non-identical T cell-depleted allogeneic marrow.

L. Bosserman, A. Freedman, N. Tarbell, 1991, Bone marrow transplantation.

Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo.

J. Gribben, J. Friedberg, D. Neuberg, 2004, Leukemia research.

Bone marrow transplantation for low-grade lymphoma and chronic lymphocytic leukemia.

A. Freedman, L. Nadler, V. Boussiotis, 1999, Seminars in hematology (Print).

Autologous and allogeneic bone marrow transplantation for poor prognosis patients with B-cell chronic lymphocytic leukemia.

D. Neuberg, G. Pinkus, A. Freedman, 1993, Blood.

Monoclonal antibody-purged bone marrow transplantation therapy for multiple myeloma.

A. Freedman, R. Soiffer, R. Schlossman, 1993, Blood.

Early initial therapy of advanced follicular lymphoma: the need for vigilance

A. Freedman, J. Sweetenham, 2011, Leukemia & lymphoma.

Non-transplant-related treatment options in follicular lymphoma.

A. Freedman, 2006, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

T-cell-depleted autologous bone marrow transplantation therapy: analysis of immune deficiency and late complications.

A. Freedman, P. Mauch, R. Soiffer, 1990, Blood.

Autologous bone marrow transplantation in poor-prognosis intermediate-grade and high-grade B-cell non-Hodgkin's lymphoma in first remission: a pilot study.

D. Neuberg, A. Freedman, N. Spector, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma at the time of second or subsequent remission: long-term follow-up.

J. Gribben, D. Neuberg, T. A. Lister, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Further characterization of prolymphocytic leukemia cells as a tumor of activated B cells

A. Berrebi, A. Freedman, S. Dagan, 1990, American journal of hematology.

Changes with in vitro Activation of the B Cell Panel Antigens

A. Freedman, D. Fisher, A. Boyd, 1986 .

Expression of B cell activation antigens on normal and malignant B cells.

A. Berrebi, D. N. Levy, A. Freedman, 1987, Leukemia.

Long-term follow-up of a phase III study of recombinant human granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid malignancies.

P. Bierman, J. Vose, D. Neuberg, 1993, Blood.

Studies of in vitro activation and differentiation of human B lymphocytes. I. Phenotypic and functional characterization of the B cell population responding to anti-Ig antibody.

A. Freedman, D. Fisher, A. Boyd, 1985, Journal of immunology.

B cell development in chronic lymphocytic leukemia.

A. Freedman, L. Nadler, 1987, Seminars in hematology.

Monoclonal antibody-purged autologous bone marrow transplantation therapy for multiple myeloma.

J. Ritz, A. Freedman, P. Mauch, 1991, Blood.

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma.

J. Gribben, D. Neuberg, J. Ritz, 1993, Blood.

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

A. LaCasce, D. Neuberg, B. Ebert, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Autologous bone marrow transplantation in acute leukemia and lymphoma following ex vivo treatment with monoclonal antibodies and complement.

S. Sallan, J. Ritz, A. Freedman, 1988, Cancer treatment and research.

Studies of the in vitro activation and differentiation of human B lymphocytes. II. Optimization of activation by anti-immunoglobulin antibody bound to beads: analysis of the role of autocrine effects on B-cell proliferation and of T-cell help in B-cell differentiation.

A. Freedman, D. Fisher, A. Boyd, 1986, Cellular immunology.

B-cell purging in autologous stem-cell transplantation for non-Hodgkin lymphoma.

A. Freedman, E. Jacobsen, 2004, The Lancet. Oncology.

Autologous bone-marrow transplantation in non-Hodgkin's lymphomas.

A. Freedman, L. Nadler, A. Pedrazzini, 1989, Biochimica et biophysica acta.

Predictive factors for radiation pneumonitis in Hodgkin lymphoma patients receiving combined-modality therapy.

A. LaCasce, A. Ng, B. Silver, 2012, International journal of radiation oncology, biology, physics.

B7, a B-cell-restricted antigen that identifies preactivated B cells.

G. Freeman, A. Freedman, L. Nadler, 1987, Journal of immunology.

beta1 integrins on human B cells Stimulation of tyrosine phosphorylation after ligation of beta7 and

A. Freedman, C. Morimoto, S. Manié, 2011 .

Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells.

R. Salgia, B. Druker, A. Freedman, 1997, Leukemia & lymphoma.

CD 6-Depleted Allogeneic Bone Marrow Transplantation for Acute Leukemia in First Complete Remission

D. Fairclough, J. Ritz, A. Freedman, 1997 .

Loss of marrow reserve from dose-intensified chemotherapy results in impaired hematopoietic reconstitution after autologous transplantation: CD34(+), CD34(+)38(-), and week-6 CAFC assays predict poor engraftment.

D. Neuberg, A. Freedman, L. Nadler, 2000, Experimental hematology.

Follicular lymphoma with bilateral testicular and epididymal involvement: Case report and review of the literature

A. Freedman, E. Jacobsen, J. Longtine, 2005, Leukemia & lymphoma.

Effect of total body irradiation dose escalation on outcome following T-cell-depleted allogeneic bone marrow transplantation.

J. Gribben, D. Neuberg, J. Ritz, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

1.11 Integrative Genomic Analysis Implicates PIK3CA and MYC in Chronic Lymphocytic Leukemia

A. Regev, N. Pochet, D. Neuberg, 2011 .

Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells.

Y. S. Choi, H. Husson, A. Freedman, 2000, Cellular immunology.

CD34(+) CD38(-) and CD34(+) HLA-DR(-) cells in BM stem cell grafts correlate with short-term engraftment but have no influence on long-term hematopoietic reconstitution after autologous transplantation.

J. Ritz, A. Freedman, H. Daley, 2006, Cytotherapy.

Early neutrophil engraftment following autologous BMT provides a functional predictor of long‐term hematopoietic reconstitution

J. Gribben, J. Ritz, D. Zahrieh, 2003, Transfusion.

Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the beta 1 integrin VLA-4.

A. Freedman, C. Benjamin, C. Morimoto, 1993, Journal of immunology.

Phenotypic Changes Occurring during in vitro Activation of Human Splenic B Lymphocytes

A. Freedman, D. Fisher, A. Boyd, 1986 .

mAb 104, a new monoclonal antibody, recognizes the B7 antigen that is expressed on activated B cells and HTLV-1-transformed T cells.

J. Banchereau, G. Freeman, A. Freedman, 1990, Immunology.

B. Druker, A. Freedman, E. Golemis, 1997, The Journal of Biological Chemistry.

HEPATIC DYSFUNCTION FOLLOWING T‐CELL-DEPLETED ALLOGENEIC BONE MARROW TRANSPLANTATION

J. Ritz, A. Freedman, N. Tarbell, 1991, Transplantation.

Cellular interactions within the germinal centre.

A. Freedman, L. Nadler, L. Nadler, 1991, Research in immunology.

Expression and function of adhesion receptors on normal B cells and B cell non-Hodgkin's lymphomas.

A. Freedman, 1993, Seminars in hematology.

Expression of vascular cell adhesion molecule-1 by follicular dendritic cells.

A. Freedman, C. Benjamin, L. Zhou, 1995, Leukemia & lymphoma.

Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia.

L. Rassenti, T. Kipps, A. Freedman, 2019, Blood advances.

Center B Cells Using Cdna Arrays Gene Expression Profiling of Follicular Lymphoma and Normal Germinal

Donna Neuberg, P. O’Connell, D. Neuberg, 2022 .

Hematologic engraftment and immune reconstitution posttransplantation with anti-B1 purged autologous bone marrow.

J. Ritz, A. Freedman, L. Nadler, 1987, Blood.

A phase I study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL

D. Neuberg, J. Ritz, A. Freedman, 2010, Leukemia.

The gene for B7, a costimulatory signal for T-cell activation, maps to chromosomal region 3q13.3-3q21.

D. Adler, C. Disteche, J. Gribben, 1992, Blood.

Human Bone Marrow Depleted of CD 33-Positive Cells Mediates Delayed but Durable Reconstitution of Hematopoiesis : Clinical Trial of MY 9 Monoclonal Antibody-Purged Autografts for the Treatment of Acute Myeloid Leukemia

A. Freedman, J. Griffin, R. Soiffer, 2003 .

J. Ritz, A. Freedman, J. Griffin, 1992, Blood.

TGFβ-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation

H. Husson, A. Freedman, F. Fend, 2004, Leukemia.

Obatoclax in combination with fludarabine and rituximab is well-tolerated and shows promising clinical activity in relapsed chronic lymphocytic leukemia

D. Neuberg, A. Freedman, D. Fisher, 2015, Leukemia & lymphoma.

A phase I study of escalated dose subcutaneous alemtuzumab given weekly with rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma

A. LaCasce, D. Neuberg, L. Rassenti, 2013, Haematologica.

Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization

C. Ihm, Eun Kyung Cho, J. Tchinda, 2010, British Journal of Haematology.

Systematic genomic screen for tyrosine kinase mutations in CLL

D. Gilliland, R. Levine, A. Freedman, 2008, Leukemia.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Donna Neuberg, Steven M Kornblau, Johannes Köster, 2016, Cancer cell.

Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia

A. Regev, N. Pochet, D. Neuberg, 2012, Clinical Cancer Research.

B-cell monoclonal antibodies and their use in clinical oncology.

A. Freedman, L. Nadler, A. Pedrazzini, 1991, Cancer investigation.

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.

J. Ritz, C. Eng, A. Freedman, 1999, Human molecular genetics.

Cell surface antigens in leukemias and lymphomas.

A. Freedman, 1996, Cancer investigation.

Immunologic markers in non-Hodgkin's lymphoma.

A. Freedman, L. Nadler, Arnold S. Freedman, 1991, Hematology/oncology clinics of North America.

Cell Surface Markers in Leukemia and Lymphoma

A. Freedman, 1991 .

Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion.

J. Ritz, A. Freedman, N. Spector, 1992, Blood.

Combination immunotherapy with rituximab and interleukin 2 in patients with relapsed or refractory follicular non‐Hodgkin's lymphoma

J. Gribben, J. Friedberg, D. Neuberg, 2002, British journal of haematology.

center B cells using cDNA arrays Gene expression profiling of follicular lymphoma and normal germinal

P. O’Connell, D. Neuberg, H. Husson, 2013 .

The relationship of chronic lymphocytic leukemia to normal activated B cells.

A. Freedman, L. Nadler, 1990, Leukemia & lymphoma.

Everolimus in combination with rituximab induces complete responses in heavily pretreated diffuse large B-cell lymphoma

A. LaCasce, D. Neuberg, A. Freedman, 2013, Haematologica.

Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival.

Marek Svoboda, A. Freedman, M. Svoboda, 2003, Blood.

Survival pathway induced by integrin in B cells

A. Freedman, M. Svoboda, Ronghui Xu, 2002 .

Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow

J. Gribben, D. Neuberg, A. Freedman, 1994 .

Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow.

J. Gribben, D. Neuberg, A. Freedman, 1994, Blood.

Autologous bone marrow transplantation in B-cell non-Hodgkin's lymphoma: very low treatment-related mortality in 100 patients in sensitive relapse.

B. Yeap, A. Freedman, P. Mauch, 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma.

J. Gribben, D. Neuberg, G. Freeman, 1991, The New England journal of medicine.

High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission.

J. Gribben, D. Neuberg, J. Ritz, 1996, Blood.

chromosomal region 3q13.3-3q21 The gene for B7, a costimulatory signal for T-cell activation, maps to

C. Disteche, J. Gribben, G. Freeman, 2011 .

Multicolour fluorescence in situ hybridization analysis of t(14;18)‐positive follicular lymphoma and correlation with gene expression data and clinical outcome

R. Gascoyne, L. Sehn, J. Connors, 2003, British journal of haematology.

Unbalanced Expression of Bcl-2 Family Proteins in Follicular Lymphoma: Contribution of CD40 Signaling in Promoting Survival

Joachim L. Schultze, Paolo Ghia, Arnold S. Freedman, 1998 .

Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival.

J. Gribben, A. Freedman, D. Dorfman, 1998, Blood.

Active idiotypic vaccination versus control immunotherapy for follicular lymphoma.

Ash A. Alizadeh, R. Tibshirani, J. Vose, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A Placebo-Controlled Phase III Trial of Patient-Specific Immunotherapy with Mitumprotimut-T (ID-KLH) and GM-CSF Following Rituximab in Patients with CD20+ Follicular Lymphoma

J. Winter, B. Djulbegovic, A. Freedman, 2008 .

Bone marrows of non-Hodgkin's lymphoma patients with a bcl-2 translocation can be purged of polymerase chain reaction-detectable lymphoma cells using monoclonal antibodies and immunomagnetic bead depletion.

J. Gribben, A. Freedman, J. Griffin, 1992, Blood.

Outcome in patients with myelodysplastic syndrome after autologous bone marrow transplantation for non-Hodgkin's lymphoma.

J. Gribben, A. LaCasce, J. Friedberg, 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission.

J. Gribben, D. Neuberg, A. Freedman, 2007, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin's lymphoma.

J. Friedberg, D. Neuberg, A. Freedman, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Autologous bone marrow transplantation after histologic transformation of indolent B cell malignancies.

J. Gribben, J. Friedberg, D. Neuberg, 1999, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Involvement of p130Cas and p105HEF1, a Novel Cas-like Docking Protein, in a Cytoskeleton-dependent Signaling Pathway Initiated by Ligation of Integrin or Antigen Receptor on Human B Cells*

R. Salgia, B. Druker, A. Freedman, 1997, The Journal of Biological Chemistry.

A phase III study of anti-B4-blocked ricin as adjuvant therapy post-autologous bone marrow transplant: CALGB 9254

B. Cheson, Sin-Ho Jung, A. Freedman, 2011, Leukemia & lymphoma.

A phase 2 study of concurrent fludarabine and rituximab for the treatment of marginal zone lymphomas

J. Friedberg, R. Fisher, D. Neuberg, 2009, British journal of haematology.

Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia.

J. Gribben, D. Neuberg, L. Sequist, 2005, Blood.

Autologous Bone Marrow Transplantation for Marginal Zone Non-Hodgkin's Lymphoma

J. Gribben, J. Friedberg, D. Neuberg, 2004, Leukemia & lymphoma.

Long-term follow-up of autologous bone marrow transplantation in patients with relapsed follicular lymphoma.

J. Gribben, D. Neuberg, J. Ritz, 1999, Blood.

High-dose chemoradiotherapy and anti-B-cell monoclonal antibody-purged autologous bone marrow transplantation in mantle-cell lymphoma: no evidence for long-term remission.

J. Gribben, D. Neuberg, J. Aster, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Autologous bone marrow transplantation in 69 patients with a history of low-grade B-cell non-Hodgkin's lymphoma.

D. Neuberg, J. Ritz, B. Yeap, 1991, Blood.

Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogeneic bone marrow transplantation.

J. Gribben, J. Friedberg, A. Freedman, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Monoclonal Antibody-Purged Autologous Bone Marrow Transplantation Therapy for Multiple Myeloma

J. Ritz, A. Freedman, R. Soiffer, 1991 .

CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission.

D. Fairclough, J. Ritz, D. Fisher, 1997, Blood.

CD6+ donor marrow T-cell depletion as the sole form of graft-versus-host disease prophylaxis in patients undergoing allogeneic bone marrow transplant from unrelated donors.

J. Ritz, A. Freedman, P. Mauch, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

CD6+ T cell depleted allogeneic bone marrow transplantation from genotypically HLA nonidentical related donors.

D. Fairclough, J. Ritz, A. Freedman, 1997, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow.

A. Freedman, N. Spector, P. Mauch, 1992, Journal of Clinical Oncology.

Anti-B-cell monoclonal antibody-purged autologous bone marrow transplantation for B-cell non-Hodgkin's lymphoma: phenotypic reconstitution and B-cell function.

J. Ritz, A. Freedman, G. Canellos, 1989, Blood.

Follicular lymphoma: 2014 update on diagnosis and management

A. Freedman, A. Tefferi, Arnold Freedman, 2014, American journal of hematology.

Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway.

G. Freeman, A. Freedman, L. Nadler, 1991, Cellular immunology.

Prognostic factors for patients with diffuse large B cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation in the positron emission tomography era

A. LaCasce, A. Freedman, P. Armand, 2013, British journal of haematology.

Follicular lymphoma: 2020 update on diagnosis and management

A. Freedman, E. Jacobsen, 2019, American journal of hematology.

Follicular lymphoma: 2018 update on diagnosis and management

A. Freedman, 2018, American journal of hematology.

CME Information: Follicular lymphoma: 2015 update on diagnosis and management

A. Freedman, 2015 .

One size does not fit all in follicular lymphoma.

A. Freedman, C. Jacobson, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

First-line treatment of indolent lymphoma: axing CHOP?

A. Freedman, C. Jacobson, 2013, The Lancet.

Follicular lymphoma: 2012 update on diagnosis and management

A. Freedman, Arnold Freedman, 2012, American journal of hematology.

Follicular lymphoma: 2011 update on diagnosis and management

A. Freedman, 2011, American journal of hematology.

The impact of external beam radiation therapy prior to autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma.

J. Friedberg, D. Neuberg, A. Freedman, 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

High-dose therapy and stem cell transplantation in follicular lymphoma

J. Friedberg, A. Freedman, 1999, Annals of Hematology.

Engraftment of autologous and allogeneic marrow HPCs after myeloablative therapy

J. Gribben, D. Neuberg, J. Ritz, 2004, Transfusion.

High-dose therapy for follicular lymphoma.

J. Friedberg, A. Freedman, J. Gribben, 2000, Oncology.

Cytogenetics and molecular basis of NHL

A. Freedman, L. Nadler, 2003 .

Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning.

A. LaCasce, A. Freedman, P. Armand, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Allogeneic transplantation with reduced-intensity conditioning for Hodgkin and non-Hodgkin lymphoma: importance of histology for outcome.

A. LaCasce, A. Freedman, P. Armand, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Risk Alleles Identified in Genome-Wide Association Studies Are Associated with Expression Quantitative Trait Loci in Chronic Lymphocytic Leukemia.

A. Regev, N. Pochet, D. Neuberg, 2012 .

Immunobiology of chronic lymphocytic leukemia.

A. Freedman, 1990, Hematology/oncology clinics of North America.

A Phase I Study of Lenalidomide in Combination with Fludarabine-Rituximab in Previously Untreated CLL/SLL.

D. Neuberg, J. Ritz, A. Freedman, 2009 .

Sequencing-Based Detection of Circulating Tumor DNA in the Autologous Stem Cell Grafts of Patients with Diffuse Large B-Cell Lymphoma Undergoing Hematopoietic Stem Cell Transplantation

A. LaCasce, J. Ritz, M. Faham, 2015 .

Detection of circulating tumour DNA in patients with aggressive B‐cell non‐Hodgkin lymphoma

A. LaCasce, D. Neuberg, Y. Oki, 2013, British journal of haematology.

Brief Definitive Report

G. Freeman, A. Freedman, N. Spector, 2022 .

Primary bone lymphoma involving bilateral tibia

A. Shinagare, A. Freedman, N. Ramaiya, 2012, American journal of hematology.

Novel presentation of intraneural nodular fasciitis of the sciatic nerve

C. Raut, A. Freedman, D. Orgill, 2007, Journal of the peripheral nervous system : JPNS.

Phase III Trial of Active Immunotherapy (FavId®, Id/KLH) Following Rituximab Induction Therapy: Clinical Responses in Patients (pts) with Follicular Non-Hodgkin’s Lymphoma (fNHL).

J. Winter, A. Freedman, S. Neelapu, 2006 .

B5, a new B cell-restricted activation antigen.

A. Freedman, D. Fisher, A. Boyd, 1985, Journal of immunology.

Relapsed or Refractory Double-Expressor and Double-Hit Lymphomas Have Inferior Progression-Free Survival After Autologous Stem-Cell Transplantation.

W. Chan, D. Weisenburger, A. LaCasce, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

PD-1 blockade for diffuse large B-cell lymphoma after autologous stem cell transplantation.

Matthew J. Frigault, A. LaCasce, M. Shipp, 2018, Blood advances.

Risk factors for development of pneumonitis after high-dose chemotherapy with cyclophosphamide, BCNU and etoposide followed by autologous stem cell transplant

A. LaCasce, D. Neuberg, A. Lane, 2012, Leukemia & lymphoma.

Biology and management of histologic transformation of indolent lymphoma.

A. Freedman, 2005, Hematology. American Society of Hematology. Education Program.

A phase II study of continuous infusion recombinant human granulocyte-macrophage colony-stimulating factor as an adjunct to autologous bone marrow transplantation for patients with non-Hodgkin's lymphoma in first remission.

D. Neuberg, A. Freedman, S. O’Day, 1994, Blood.

High dose therapy and autologous stem cell transplantation in follicular non-Hodgkin's lymphoma.

J. Gribben, A. Freedman, L. Nadler, 1998, Leukemia & lymphoma.

Association between clonogenic cell growth and clinical risk group in B-cell chronic lymphocytic leukemia.

S. Cannistra, A. Freedman, L. Nadler, 1990, Blood.

MCP‐1 modulates chemotaxis by follicular lymphoma cells

D. Neuberg, H. Husson, A. Freedman, 2001, British journal of haematology.

Epstein-barr virus-associated diffuse large B-cell lymphoma in an immunocompetent woman.

J. Kutok, A. Freedman, O. Pozdnyakova, 2010, Journal of Clinical Oncology.

Early stage follicular lymphoma, current management and controversies

A. Freedman, C. Jacobson, 2012, Current opinion in oncology.

Therapies for advanced and high-risk follicular lymphoma

A. Freedman, 1999 .

CpG Oligonucleotide (1018 ISS) May Overcome Rituximab (R) Resistance in Follicular Lymphoma (FL) through Enhanced ADCC, T Cell Expansion, and Alteration of Tumor Microenvironment.

J. Friedberg, R. Fisher, R. Coffman, 2005 .

A prospective study of minimal residual disease in patients with diffuse large B-cell lymphoma using an Ig-NGS assay

A. LaCasce, A. Freedman, P. Armand, 2020, Leukemia & lymphoma.

Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation

A. Freedman, M. Svoboda, A. Astier, 2004, Leukemia.

Phase IA/II, multicentre, open‐label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non‐Hodgkin or Hodgkin lymphoma

Andreas Engert, Arnold S. Freedman, Martin J. S. Dyer, 2014, British journal of haematology.

Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.

R. Salgia, B. Druker, A. Freedman, 1997, Experimental hematology.

Stimulation of tyrosine phosphorylation after ligation of beta7 and beta1 integrins on human B cells.

A. Freedman, C. Morimoto, S. Manié, 1996, Blood.

Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses

Zachary T. Giaccone, S. Tyekucheva, Catherine J. Wu, 2020, American journal of hematology.

Clinical Investigation : Lymphoma Low-Dose Involved-Field Radiation in the Treatment of Non-Hodgkin Lymphoma : Predictors of Response and Treatment Failure

A. Ng, B. Silver, A. Freedman, 2022 .

Prognostic Value of Circulating Tumor DNA (ctDNA) in Autologous Stem Cell Graft and Post-Transplant Plasma Samples Among Patients with Diffuse Large B-Cell Lymphoma

A. LaCasce, A. Freedman, P. Armand, 2020 .

Persistence of dysphagia and odynophagia after mediastinal radiation and chemotherapy in patients with lung cancer or lymphoma.

A. Ng, A. Recht, A. Freedman, 2016, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

Acute and chronic pulmonary complications following autologous bone marrow transplantation in non-Hodgkin's lymphoma.

J. Ritz, A. Freedman, N. Tarbell, 1990, Bone marrow transplantation.

B-Cell Function and Ontogeny

A. Freedman, 1990 .

Imatinib mesylate lacks efficacy in relapsed/refractory peripheral T cell lymphoma

A. LaCasce, D. Neuberg, P. D. Dal Cin, 2015, Leukemia and Lymphoma.

Double Expressing (MYC/BCL2) and Double-Hit Diffuse Large B-Cell Lymphomas Have Inferior Survival Following Autologous Stem Cell Transplantation

D. Weisenburger, A. LaCasce, A. Nademanee, 2015 .

Response to low-dose involved-field radiotherapy in patients with non-Hodgkin's lymphoma.

A. Ng, B. Silver, A. Freedman, 2008, Annals of oncology : official journal of the European Society for Medical Oncology.

Obatoclax in Combination with Fludarabine and Rituximab (FR) Is Well-Tolerated and Shows Promising Clinical Activity in Relapsed CLL/SLL

D. Neuberg, A. Freedman, D. Fisher, 2011 .

Myelodysplastic syndrome as a late complication following autologous bone marrow transplantation for non-Hodgkin's lymphoma.

D. Neuberg, J. Aster, A. Freedman, 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The role of Aktand RAFTK in beta1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells.

S. Sarkar, A. Freedman, M. Svoboda, 2002, Leukemia & lymphoma.

Reply to J. Mehta

A. LaCasce, A. Freedman, P. Armand, 2009 .

54: Inclusion of Sirolimus in the GVHD Prophylaxis Regimen is Associated with Improved Survival in Patients with Lymphoma Undergoing Allogeneic Transplantation

A. LaCasce, A. Freedman, P. Armand, 2008 .

Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes stem cell reserve for autologous bone marrow transplantation.

J. Gribben, D. Neuberg, J. Ritz, 1997, Blood.

Minimal residual disease in patients with diffuse large B-cell lymphoma undergoing autologous stem cell transplantation

E. D. Jacobsen, A. LaCasce, M. Shipp, 2022, Blood advances.

PD-1 Blockade with Pembrolizumab for Classical Hodgkin Lymphoma after Autologous Stem Cell Transplantation

A. LaCasce, M. Shipp, J. Ritz, 2018, Blood.

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma.

J. Gribben, D. Neuberg, A. Freedman, 1993, Blood.

Phase IA/II, multicentre, open‐label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non‐Hodgkin or Hodgkin lymphoma

M. Dyer, A. Freedman, D. Heo, 2014, British journal of haematology.

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

A. LaCasce, D. Neuberg, B. Ebert, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Down-regulation of CD9 expression and its correlation to tumor progression in B lymphomas.

I. Lossos, D. Zahrieh, A. Freedman, 2010, The American journal of pathology.

A Phase I Study of IMGN529, an Antibody-Drug Conjugate (ADC) Targeting CD37, in Adult Patients with Relapsed or Refractory B-Cell Non-Hodgkin’s Lymphoma (NHL)

I. Flinn, A. Freedman, A. Stathis, 2014 .

A Phase 2 Study of Fludarabine and Rituximab for the Treatment of Marginal Zone Lymphomas.

J. Friedberg, R. Fisher, D. Neuberg, 2007 .

Center B Cells Using Cdna Arrays Gene Expression Profiling of Follicular Lymphoma and Normal Germinal

D. Neuberg, H. Husson, A. Freedman, 2022 .

Low-dose involved-field radiation in the treatment of non-hodgkin lymphoma: predictors of response and treatment failure.

A. Ng, B. Silver, A. Freedman, 2012, International journal of radiation oncology, biology, physics.

High Resolution Genomic Analysis In CLL Demonstrates Genomic Stability In Untreated Patients and Novel Markers of Progression In Treated Patients

D. Neuberg, M. Hanna, L. Macconaill, 2010 .