I. Tietjen

发表

Single-Cell Transcriptional Analysis of Neuronal Progenitors

J. Rihel, C. Dulac, I. Tietjen, 2003, Neuron.

Binding and Proton Blockage by Amantadine Variants of the Influenza M2WT and M2S31N Explained.

G. Gauglitz, I. Tietjen, T. Cross, 2017, Journal of medicinal chemistry.

Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products

David E. Williams, R. Andersen, I. Tietjen, 2018, Viruses.

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening

I. Tietjen, W. Sippl, C. V. Simoben, 2020, Frontiers in Pharmacology.

Put a cork in it: Plugging the M2 viral ion channel to sink influenza

Jun Wang, I. Tietjen, D. Fedida, 2020, Antiviral Research.

Novel Acylguanidine-Based Inhibitor of HIV-1

I. Tietjen, J. Richard, A. Finzi, 2016, Journal of Virology.

Natural product-derived compounds in HIV suppression, remission, and eradication strategies.

R. Andersen, I. Tietjen, F. Ntie‐Kang, 2018, Antiviral research.

Disease-associated mutations affect GPR56 protein trafficking and cell surface expression.

C. Walsh, L. Bu, I. Tietjen, 2007, Human molecular genetics.

Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol

Marie-Pierre Dubé, Michael R. Hayden, Amina Barhdadi, 2012, PloS one.

Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans[S]

M. Hayden, Kenny K. Wong, L. Mitnaul, 2014, Journal of Lipid Research.

Mechanisms of Action of Novel Influenza A/M2 Viroporin Inhibitors Derived from Hexamethylene Amiloride

I. Tietjen, D. Fedida, M. Niikura, 2016, Molecular Pharmacology.

Inhibition of NF‐&kgr;B‐dependent HIV‐1 replication by the marine natural product bengamide A

M. Wainberg, David E. Williams, R. Andersen, 2018, Antiviral research.

The impact of partial and complete loss of function mutations in endothelial lipase on hdl levels and functionality in humans

M. Hayden, C. Duijn, Kenny K. Wong, 2018 .

Immune Responses of a Novel Bi-Cistronic SARS-CoV-2 DNA Vaccine Following Intradermal Immunization With Suction Delivery

J. Shan, L. Montaner, J. Zahn, 2022, Frontiers in Virology.

Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding

L. Montaner, I. Tietjen, J. Salvino, 2022, Analytical and Bioanalytical Chemistry.

Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans

M. Hayden, J. Kastelein, I. Tietjen, 2011, Clinical genetics.

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1 (DMT1): Preclinical Efficacy Against Iron Overload and Safety Evaluation

I. Tietjen, Y. P. Goldberg, Matthew Waldbrook, 2022, bioRxiv.

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus

Pascal Amoa Onguéné, David E. Williams, R. Andersen, 2020, Molecules.

Unciaphenol, an Oxygenated Analogue of the Bergman Cyclization Product of Uncialamycin Exhibits Anti-HIV Activity.

David E. Williams, R. Andersen, J. Davies, 2015, Organic letters.

Artificial intelligence for antiviral drug discovery in low resourced settings: A perspective

L. Montaner, I. Tietjen, Miquel Duran-Frigola, 2022, Frontiers in Drug Discovery.

Transmembrane polar residues of TCR beta chain are required for signal transduction.

L. Spain, I. Tietjen, D. Wiest, 1998, International immunology.

Comprehensive EMX2 genotyping of a large schizencephaly case series

G. Shaw, A. Barkovich, I. Tietjen, 2007, American journal of medical genetics. Part A.

Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors

Pascal Amoa Onguéné, C. Rice, I. Tietjen, 2015, PloS one.

Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

Antonios Kolocouris, Christina Tzitzoglaki, Timothy A. Cross, 2014, Journal of medicinal chemistry.

Two novel mutations in apolipoprotein C3 underlie atheroprotective lipid profiles in families

M. Hayden, J. Kastelein, J. Kastelein, 2014, Clinical genetics.

Croton megalobotrys Müll Arg. and Vitex doniana (Sweet): Traditional medicinal plants in a three-step treatment regimen that inhibit in vitro replication of HIV-1.

I. Tietjen, Jianbo Xiao, D. Fedida, 2016, Journal of ethnopharmacology.

Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphofia foliosa Hochst.

Serge A. T. Fobofou, K. Becker, I. Tietjen, 2019, Journal of pharmaceutical and biomedical analysis.

The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal

L. Montaner, K. Mounzer, I. Tietjen, 2020, The Journal of Biological Chemistry.

HPLC-Based Purification and Isolation of Potent Anti-HIV and Latency Reversing Daphnane Diterpenes from the Medicinal Plant Gnidia sericocephala (Thymelaeaceae)

L. Montaner, T. Klimkait, K. Mounzer, 2022, Viruses.

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria.

I. Tietjen, R. Gasser, J. White, 2020, Journal of natural products.

Sesterterpenoids Isolated from the Sponge Phorbas sp. Activate Latent HIV-1 Provirus Expression.

David E. Williams, R. Andersen, I. Tietjen, 2016, The Journal of organic chemistry.

Transmembrane polar residues of TCR β chain are required for signal transduction

I. Tietjen, D. Wiest, S. Fuller-Espie, 1998 .

Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics

I. Nabi, David E. Williams, R. Andersen, 2022, Antiviral Research.

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

J. Casanova, S. Seligman, C. Rice, 2019, The Journal of experimental medicine.

The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

A. Hofman, M. Hayden, C. V. van Duijn, 2013, Circulation. Cardiovascular genetics.

EMX2‐independent familial schizencephaly: Clinical and genetic analyses

C. Walsh, I. Tietjen, B. Chang, 2005, American journal of medical genetics. Part A.

Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT.

M. Hayden, J. Kastelein, I. Tietjen, 2012, Biochimica et biophysica acta.

The Croton megalobotrys Müll Arg. traditional medicine in HIV/AIDS management: Documentation of patient use, in vitro activation of latent HIV-1 provirus, and isolation of active phorbol esters.

David E. Williams, R. Andersen, I. Tietjen, 2018, Journal of ethnopharmacology.

Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning

P. Ellen Grant, Hideyuki Okano, Kiho Im, 2014, Science.

Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.

L. Montaner, K. Mounzer, I. Tietjen, 2021, Biochemical pharmacology.

Using a Bioactive Eremophila-Derived Serrulatane Scaffold to Generate a Unique Carbamate Library for Anti-infective Evaluations.

L. Montaner, I. Tietjen, R. Gasser, 2023, Journal of natural products.

Ansellone J, a Potent in Vitro and ex Vivo HIV-1 Latency Reversal Agent Isolated from a Phorbas sp. Marine Sponge.

David E. Williams, R. Andersen, L. Montaner, 2022, Journal of natural products.

The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants

L. Montaner, I. Tietjen, H. Ertl, 2021, bioRxiv.

ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels

M. Hayden, M. Dubé, I. Tietjen, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Capillasterin A, a Novel Pyrano[2,3-f]chromene from the Australian Crinoid Capillaster multiradiatus

I. Tietjen, A. Carroll, Rohan A. Davis, 2019, Marine drugs.

The Natural Stilbenoid (–)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9

L. Montaner, K. Mounzer, I. Tietjen, 2023, Antimicrobial agents and chemotherapy.

An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions.

I. Tietjen, K. Richard, K. Andrae-Marobela, 2023, Journal of ethnopharmacology.

Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold.

L. Montaner, I. Tietjen, R. Gasser, 2021, Phytochemistry.

Single-cell transcriptional profiles and spatial patterning of the mammalian olfactory epithelium.

J. Rihel, C. Dulac, I. Tietjen, 2005, The International journal of developmental biology.

The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

M. Hayden, Kenny K. Wong, L. Mitnaul, 2013, Circulation. Cardiovascular genetics.