J. B. Jaynes

发表

Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients.

M. Fujioka, Y. Emi-Sarker, G. Yusibova, 1999, Development.

Embryonic Origins of a Motor System:Motor Dendrites Form a Myotopic Mapin Drosophila

M. Bate, M. Landgraf, M. Fujioka, 2003, PLoS biology.

Direct visualization of transcriptional activation by physical enhancer–promoter proximity

Thomas Gregor, M. Fujioka, J. B. Jaynes, 2017, bioRxiv.

Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers.

M. Fujioka, J. B. Jaynes, Miki Fujioka, 2012, Developmental biology.

Early even-skipped stripes act as morphogenetic gradients at the single cell level to establish engrailed expression.

M. Fujioka, T. Goto, J. B. Jaynes, 1995, Development.

Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila

R. Mann, Masatomo Kobayashi, E. Tolkunova, 2003, Development.

Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm.

Zhe Han, Rolf Bodmer, R. Bodmer, 2002, Developmental biology.

Expression of a transfected mouse muscle-creatine kinase gene is induced upon growth factor deprivation of myogenic but not of nonmyogenic cells.

J. Johnson, J. B. Jaynes, S. Hauschka, 1989, Developmental biology.

Regulation of creatine kinase induction in differentiating mouse myoblasts

J. B. Jaynes, J. Chamberlain, S. Hauschka, 1985, Molecular and Cellular Biology.

A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer

S. Waldman, P. Fortina, J. B. Jaynes, 2021, Cellular and molecular gastroenterology and hepatology.

The mouse muscle creatine kinase cDNA and deduced amino acid sequences: Comparison to evolutionarily related enzymes

J. B. Jaynes, J. Chamberlain, S. Hauschka, 2005, Journal of Molecular Evolution.

The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila

E. Alnemri, M. Fujioka, J. B. Jaynes, 2008, Cell Death and Differentiation.

Regulation of creatine kinase induction in differentiating mouse myoblasts

J. B. Jaynes, J. Chamberlain, S. Hauschka, 1985, Molecular and cellular biology.

A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo.

J. B. Jaynes, S. T. Smith, J B Jaynes, 1996, Development.

Active repression of transcription by the engrailed homeodomain protein.

P. O’Farrell, J. B. Jaynes, Patrick H. O'Farrell, 1991, The EMBO journal.

Two Distinct Types of Repression Domain in Engrailed: One Interacts with the Groucho Corepressor and Is Preferentially Active on Integrated Target Genes

Masatomo Kobayashi, E. Tolkunova, M. Fujioka, 1998, Molecular and Cellular Biology.

Production of transgenic Drosophila.

M. Fujioka, J. B. Jaynes, A. Bejsovec, 2000, Methods in molecular biology.

Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans

M. Fujioka, J. B. Jaynes, P. Schedl, 2016, PLoS genetics.

A complex array of DNA-binding proteins required for pairing-sensitive silencing by a polycomb group response element from the Drosophila engrailed gene.

M. Fujioka, J. B. Jaynes, M. Whiteley, 2002, Genetics.

Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference

J. B. Jaynes, F. Schweisguth, S. Petruk, 2006, Cell.

Using competition assays to quantitatively model cooperative binding by transcription factors and other ligands.

J. B. Jaynes, Jacob R Peacock, 2017, Biochimica et biophysica acta. General subjects.

Using competition assays to quantitatively model cooperative binding by transcription factors and other ligands

J. B. Jaynes, Jacob R Peacock, 2017, bioRxiv.

Dynamic interplay between enhancer-promoter topology and gene activity

Thomas Gregor, M. Fujioka, J. B. Jaynes, 2018, Nature Genetics.

Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries.

Z. Paroush, M. Fujioka, J. B. Jaynes, 2001, Development.

Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila

Lucy Cherbas, J. B. Jaynes, E. Canaani, 2003, Nature.

Defining the Boundaries of Polycomb Domains in Drosophila

M. Fujioka, J. B. Jaynes, J. Kassis, 2020, Genetics.

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site

P. O’Farrell, J. B. Jaynes, 1988, Nature.

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer

J. Johnson, J. B. Jaynes, S. Hauschka, 1988, Molecular and cellular biology.

Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.

R. Mann, M. Fujioka, J. B. Jaynes, 2012, Developmental biology.

sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein

S. Srinivasula, E. Alnemri, Yigong Shi, 2002, Current Biology.

Even-skipped, acting as a repressor, regulates axonal projections in Drosophila

N. Patel, M. Landgraf, M. Fujioka, 2003, Development.

A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication

M. Fujioka, J. B. Jaynes, Xian-Hui Wu, 2009, Development.

The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site

M. Fujioka, G. Yusibova, J. B. Jaynes, 2008, Development.

The Drosophila eve Insulator Homie Promotes eve Expression and Protects the Adjacent Gene from Repression by Polycomb Spreading

M. Fujioka, J. B. Jaynes, Gui-zhi Sun, 2013, PLoS genetics.

Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes

M. Fujioka, J. B. Jaynes, P. Georgiev, 2017, BioEssays : news and reviews in molecular, cellular and developmental biology.

Analysis of the DNA-binding properties of Alx1, an evolutionarily conserved regulator of skeletogenesis in echinoderms

J. B. Jaynes, Jennifer Guerrero-Santoro, C. Ettensohn, 2021, The Journal of biological chemistry.

Inserting the Ftz homeodomain into engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo.

J. B. Jaynes, S. T. Smith, A. John, 1995, Development.

Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity

J. B. Jaynes, W. Zhu, S. Hanes, 2001, Development, Genes and Evolution.

Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts

J. Johnson, J. B. Jaynes, J. Chamberlain, 1986, Molecular and cellular biology.

Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development.

M. Fujioka, J. B. Jaynes, S. Petruk, 2011, Molecular cell.

Embryonic even skipped–Dependent Muscle and Heart Cell Fates Are Required for Normal Adult Activity, Heart Function, and Lifespan

R. Bodmer, M. Fujioka, G. Yusibova, 2005, Circulation research.

even skipped is required to produce a trans-acting signal for larval neuroblast proliferation that can be mimicked by ecdysone.

M. Fujioka, J. B. Jaynes, M. Kobayashi, 2001, Development.

Drosophila homeobox gene eve enhances trol, an activator of neuroblast proliferation in the larval CNS.

M. Fujioka, J. B. Jaynes, S. Datta, 1998, Developmental genetics.

Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D.

R. Yeh, A. Robie, Ting Wang, 2014, Developmental biology.

Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila

S. G. Robinson, M. Bate, M. Fujioka, 1999, Current Biology.

Erratum to “Drawing lines in the sand: even skipped et al. and parasegment boundaries” [Dev. Biol. 269 (2004) 609–622]

M. Fujioka, J. B. Jaynes, 2004 .

Drawing lines in the sand: even skipped et al. and parasegment boundaries.

M. Fujioka, J. B. Jaynes, 2004, Developmental biology.

Specification of motoneuron fate in Drosophila: integration of positive and negative transcription factor inputs by a minimal eve enhancer.

C. Doe, M. Fujioka, J. B. Jaynes, 2003, Journal of neurobiology.

An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference

M. Fujioka, J. B. Jaynes, Anastasiya Nezdyur, 2021, PLoS genetics.

The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundaries.

Susan J. Brown, N. Patel, M. Fujioka, 2002, Development.

Transcriptional Regulation oftheMuscleCreatine Kinase Geneand Regulated Expression inTransfected MouseMyoblasts

J. B. Jaynes, Jane E. Johnson, S. Hauschka, 1986 .

Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development.

M. Fujioka, J. B. Jaynes, S. Petruk, 2011, Molecules and Cells.

The homie insulator has sub-elements with different insulating and long-range pairing properties

M. Fujioka, J. B. Jaynes, Wenfan Ke, 2024, bioRxiv.

Chromosome Structure I: Loop extrusion or boundary:boundary pairing?

M. Fujioka, J. B. Jaynes, Wenfan Ke, 2024, bioRxiv.

Chromosome Structure II: Stem-loops and Circle-loops

M. Fujioka, J. B. Jaynes, Wenfan Ke, 2024, bioRxiv.

Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.

R. Mann, M. Fujioka, J. B. Jaynes, 2012, Developmental biology.