Wenan Chen

发表

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

Wenan Chen, Yan Li, J. Easton, 2018, Genome Biology.

From genome-wide associations to candidate causal variants by statistical fine-mapping

D. Schaid, N. Larson, Wenan Chen, 2018, Nature Reviews Genetics.

Automated measurement of midline shift in brain ct images and its application in computer-aided medical decision making

Wenan Chen, K. Najarian, 2010 .

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Beisi Xu, H. Chi, Wenan Chen, 2018, Nature.

Automated segmentation of lateral ventricles in brain CT images

Soo-Yeon Ji, K. Najarian, Wenan Chen, 2008, 2008 IEEE International Conference on Bioinformatics and Biomeidcine Workshops.

A Generalized Sequential Bonferroni Procedure for GWAS in Admixed Populations Incorporating Admixture Mapping Information into Association Tests

Shumei S. Sun, Xiaofeng Zhu, Huaizhen Qin, 2015, Human Heredity.

Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

Gregory A. Poland, Richard B. Kennedy, Daniel J. Schaid, 2015, Genetics.

Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary Statistics

Daniel J Schaid, Wenan Chen, D. Schaid, 2016, Genetics.

A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.

Heather L. Mulder, Jason R. Hodges, Celeste K. Kanne, 2021, Blood advances.

XAF1 as a modifier of p53 function and cancer susceptibility

Shondra M. Pruett-Miller, Mark George Thomas, M. Yeager, 2020, Science Advances.

PedBLIMP: Extending Linear Predictors to Impute Genotypes in Pedigrees

Daniel J Schaid, Wenan Chen, D. Schaid, 2014, Genetic epidemiology.

Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

J. Gee, J. Trojanowski, M. Grossman, 2020, EMBO molecular medicine.

Machine learning suggests polygenic contribution to cognitive dysfunction in amyotrophic lateral sclerosis

J. Gee, J. Trojanowski, M. Grossman, 2020 .

A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing

Wenan Chen, J. Easton, Gang Wu, 2020, Computational and structural biotechnology journal.

Accurate genomic variant detection in single cells with primary template-directed amplification

Shondra M. Pruett-Miller, C. Gawad, Wenan Chen, 2021, Proceedings of the National Academy of Sciences.

A rare variant analysis framework using public genotype summary counts to prioritize disease-predisposition genes

D. Schaid, D. Ellison, Wenan Chen, 2022, Nature Communications.

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.

P. Sullivan, E. J. van den Oord, A. Shabalin, 2015, Alcoholism, clinical and experimental research.

Estimated number of adult survivors of childhood cancer in United States with cancer‐predisposing germline variants

Aman N. Patel, Heather L. Mulder, Carmen L. Wilson, 2019, Pediatric blood & cancer.

Recent advances and challenges of rare variant association analysis in the biobank sequencing era

N. Larson, Wenan Chen, B. Coombes, 2022, Frontiers in Genetics.

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

H. Chi, P. Dash, P. Thomas, 2018, Science Immunology.

Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data

Heather L. Mulder, Wenan Chen, Yan Li, 2019, Nucleic acids research.

LCA robustly reveals subtle diversity in large-scale single-cell RNA-seq data

Yan Li, Celeste Rosencrance, John Easton, 2018, bioRxiv.

Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent

C. Li, J. Krystal, Heping Zhang, 2013, Pharmacogenetics and genomics.

From genome-wide associations to candidate causal variants by statistical fine-mapping

D. Schaid, N. Larson, Wenan Chen, 2018, Nature Reviews Genetics.

Accurate genomic variant detection in single cells with primary template-directed amplification

Charles Gawad, Xiang Chen, Veronica Gonzalez, 2020, Proceedings of the National Academy of Sciences.

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model.

M. Leboyer, M. Frye, G. Jenkins, 2017, Journal of affective disorders.

MethylPCA: a toolkit to control for confounders in methylome-wide association studies

Patrick F. Sullivan, Wenan Chen, Patrik K. E. Magnusson, 2013, BMC Bioinformatics.

CoCoRV: a rare variant analysis framework using publicly available genotype summary counts to prioritize germline disease-predisposition genes

D. Ellison, Wenan Chen, Gang Wu, 2021, bioRxiv.

A High-risk Haplotype for Premature Menopause in Childhood Cancer Survivors Exposed to Gonadotoxic Therapy

Carmen L. Wilson, S. Chanock, Zhaoming Wang, 2018, Journal of the National Cancer Institute.

The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model

R. Heath, E. Lalli, J. Rehg, 2021, Cancer Research.

Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer.

Yadav Sapkota, Celeste Rosencrance, Xiaotu Ma, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Enrichment of heterozygous germline RECQL4 loss-of-function variants in pediatric osteosarcoma

Aman N. Patel, Michael N. Edmonson, J. Downing, 2019, Cold Spring Harbor molecular case studies.

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

D. Morrow, J. Varon, Wenan Chen, 2022, bioRxiv.

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

C. Lewis, M. Frye, G. Jenkins, 2018, bioRxiv.

Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults.

Guimin Gao, Patrick F Sullivan, Wenan Chen, 2014, JAMA psychiatry.

Double genomic control is not effective to correct for population stratification in meta-analysis for genome-wide association studies

Shumei S. Sun, Wenan Chen, K. Archer, 2012, Front. Gene..

Small Sample Kernel Association Tests for Human Genetic and Microbiome Association Studies

Jun Chen, Ni Zhao, Wenan Chen, 2016, Genetic epidemiology.

Predictability of intracranial pressure level in traumatic brain injury: features extraction, statistical analysis and machine learning-based evaluation

Kayvan Najarian, Kevin Ward, Charles Cockrell, 2013, Int. J. Data Min. Bioinform..

Automated Intracranial Pressure Prediction Using Multiple Features Sources

Kayvan Najarian, Charles Cockrell, Ashwin Belle, 2013, 2013 International Conference on Information Science and Applications (ICISA).

Intracranial pressure level prediction in traumatic brain injury by extracting features from multiple sources and using machine learning methods

Kayvan Najarian, Kevin Ward, Charles Cockrell, 2010, 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

Texture Analysis of Brain CT Scans for ICP Prediction

Rebecca Smith, Kayvan Najarian, Kevin Ward, 2010, ICISP.

Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia

M. Loh, C. Pui, D. Teachey, 2022, Blood advances.

Rare Deleterious TCF3 Germline Variants and Predisposition to Acute Lymphoblastic Leukemia in Children

M. Loh, C. Pui, D. Teachey, 2022, Blood.

Shufeng Jiedu capsules protect rats against LPS-induced acute lung injury via activating NRF2-associated antioxidant pathway.

Wenan Chen, Z. Tao, Mingming Xue, 2020, Histology and histopathology.

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

Shondra M. Pruett-Miller, S. Cairo, Taosheng Chen, 2023, Nature communications.

Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma.

Jia Liu, M. Tucker, E. Rampersaud, 2022, Blood.

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model

M. Leboyer, M. Frye, G. Jenkins, 2017 .

A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell–Cell Communication

Wenan Chen, Xiang Chen, Hongjian Jin, 2023, Cells.

Actual Midline Estimation from Brain CT Scan Using Multiple Regions Shape Matching

Kayvan Najarian, Kevin Ward, Wenan Chen, 2010, 2010 20th International Conference on Pattern Recognition.

Automated ventricular systems segmentation in brain CT images by combining low-level segmentation and high-level template matching

Rebecca Smith, Kayvan Najarian, Kevin Ward, 2009, BMC Medical Informatics Decis. Mak..

A Rapid Association Test Procedure Robust under Different Genetic Models Accounting for Population Stratification

Shumei S. Sun, Qizhai Li, Wenan Chen, 2013, Human Heredity.

Germline Genetic NBN Variation and Predisposition to B-cell Acute Lymphoblastic Leukemia in Children

M. Loh, C. Pui, Wenan Chen, 2023, Research square.

Traumatic Pelvic Injury Outcome Prediction by Extracting Features from Relevant Medical Records and X-Ray Images

Rebecca Smith, Kayvan Najarian, Kevin Ward, 2009, 2009 IEEE International Conference on Bioinformatics and Biomedicine.

Jiedu capsules protect rats against LPS-induced acute lung injury via activating NRF 2-associated antioxidant pathway

Wenan Chen, Z. Tao, Mingming Xue, 2020 .

A Generalized Sequential Bonferroni Procedure Using Smoothed Weights for Genome-Wide Association Studies Incorporating Information on Hardy-Weinberg Disequilibrium among Cases

D. Allison, Qizhai Li, Wenan Chen, 2011, Human Heredity.

A Generalized Sequential Bonferroni Procedure for GWAS in Admixed Populations Incorporating Admixture Mapping Information into Association Tests

Shumei S. Sun, Xiaofeng Zhu, Huaizhen Qin, 2015, Human Heredity.

The Condition of Kernelizing an Algorithm and an Equivalence Between Kernel Methods

Hongbin Zhang, WenAn Chen, Wenan Chen, 2007, IbPRIA.

Rule-based Computer Aided Decision Making for Traumatic Brain Injuries

Kayvan Najarian, Ashwin Belle, Wenan Chen, 2014, Machine Learning in Healthcare Informatics.

Automated midline shift and intracranial pressure estimation based on brain CT images.

Kayvan Najarian, Charles Cockrell, Ashwin Belle, 2013, Journal of visualized experiments : JoVE.

Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

D. Schaid, Wenan Chen, R. Kennedy, 2015, Genetics.

Agent based modeling of blood coagulation system: Implementation using a GPU based high speed framework

Qi Li, Kayvan Najarian, Vojislav Kecman, 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.

P. Sullivan, E. J. van den Oord, A. Shabalin, 2015, Alcoholism, clinical and experimental research.