V. Dirsch

Z. Bago-Horvath, W. Jäger, A. Atanasov, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The cephalostatin way of apoptosis.

A. Vollmar, V. Dirsch, N. López-Antón, 2008, Journal of natural products.

A two-step chemical and circular dichroic method for assigning the absolute configurations of sphingosines

A. Bielawska, Y. Hannun, K. Nakanishi, 1995 .

6‐Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP‐1‐Derived Macrophages

A. Atanasov, E. Heiss, V. Dirsch, 2018, Molecular nutrition & food research.

Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents

A. Atanasov, V. Dirsch, D. Schachner, 2021, Biomedicines.

Distinct Anti-Migratory Effects of Resveratrol on EGF- versus PDGF-Stimulated Vascular Smooth Muscle Cells

E. Heiss, V. Dirsch, Mario Kumerz, 2009 .

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.

J. Hohmann, T. Szekeres, W. Jäger, 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: drug testing in a 3D model

T. Szekeres, W. Jäger, A. Atanasov, 2013, Archives of Toxicology.

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin

T. Szekeres, W. Jäger, A. Atanasov, 2013, Archives of Toxicology.

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

J. Hohmann, T. Szekeres, W. Jäger, 2015, Cancer letters.

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

T. Szekeres, W. Jäger, A. Atanasov, 2013, Archives of Toxicology.

Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis.

A. Vollmar, V. Dirsch, H. Nagasawa, 2008, European journal of pharmacology.

Evaluation of the Analgesic and Anti-Inflammatory Effects of a Brazilian Green Propolis

M. C. Marcucci, A. Vollmar, V. Dirsch, 2006, Planta medica.

Imbricaric Acid and Perlatolic Acid: Multi-Targeting Anti-Inflammatory Depsides from Cetrelia monachorum

O. Werz, A. Atanasov, E. Heiss, 2013, PloS one.

Synthetic cryptolepine inhibits DNA binding of NF-κB

A. Vollmar, E. Heiss, V. Dirsch, 2007 .

Lignan Derivatives from Krameria lappacea Roots Inhibit Acute Inflammation in Vivo and Pro-inflammatory Mediators in Vitro

R. Bauer, O. Werz, A. Atanasov, 2011, Journal of natural products.

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

R. Bauer, A. Atanasov, D. Schuster, 2014, Biochemical pharmacology.

Part of the Special Issue: Metabolism 2014 - Alterations of metabolic pathways as therapeutic targets Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARg): a review

R. Bauer, A. Atanasov, D. Schuster, 2014 .

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR.

V. Dirsch, A. Ladurner, V. Hiebl, 2018, Biotechnology advances.

Ethnopharmacological in vitro studies on Austria's folk medicine—An unexplored lore in vitro anti-inflammatory activities of 71 Austrian traditional herbal drugs

A. Atanasov, N. Fakhrudin, E. Heiss, 2013, Journal of ethnopharmacology.

Plant extracts in cell-based anti-inflammatory assays—Pitfalls and considerations related to removal of activity masking bulk components

R. Bauer, M. Zehl, A. Atanasov, 2014 .

Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects.

A. Vollmar, R. Gebhardt, V. Dirsch, 2006, The American journal of clinical nutrition.

Structural requirements of sesquiterpene lactones to inhibit LPS-induced nitric oxide synthesis in RAW 264.7 macrophages.

A. Vollmar, H. Stuppner, V. Dirsch, 2000, Bioorganic & medicinal chemistry.

Natural products in drug discovery: advances and opportunities

R. Bauer, A. Sureda, D. Bredt, 2021, Nature reviews. Drug discovery.

A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort

Judith M Rollinger, Rainer de Martin, J. Rollinger, 2020, Biomolecules.

Polyyne Hybrid Compounds from Notopterygium incisum with Peroxisome Proliferator-Activated Receptor Gamma Agonistic Effects

R. Bauer, S. Noha, A. Atanasov, 2014, Journal of natural products.

Impact of natural products on the cholesterol transporter ABCA1.

A. Atanasov, E. Heiss, V. Dirsch, 2019, Journal of ethnopharmacology.

Screening of Vietnamese medicinal plants for NF-κB signaling inhibitors: Assessing the activity of flavonoids from the stem bark of Oroxylum indicum

A. Atanasov, E. Heiss, H. Stuppner, 2015, Journal of ethnopharmacology.

Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level

A. Atanasov, E. Heiss, H. Stuppner, 2017, Journal of natural products.

Impact of Trans-Resveratrol-Sulfates and -Glucuronides on Endothelial Nitric Oxide Synthase Activity, Nitric Oxide Release and Intracellular Reactive Oxygen Species

E. Heiss, V. Dirsch, D. Schachner, 2014, Molecules.

Synergy Study of the Inhibitory Potential of Red Wine Polyphenols on Vascular Smooth Muscle Cell Proliferation

A. Atanasov, E. Heiss, V. Dirsch, 2012, Planta Medica.

Synthetic cryptolepine inhibits DNA binding of NF-kappaB.

A. Vollmar, E. Heiss, V. Dirsch, 2007, Bioorganic & medicinal chemistry.

Magnolol dimer-derived fragments as PPARγ-selective probes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8ob01745j

D. Schuster, V. Dirsch, V. Temml, 2018, Organic & biomolecular chemistry.

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

A. Atanasov, E. Heiss, V. Dirsch, 2015, Free radical biology & medicine.

NADPH oxidases 1 and 4 mediate cellular senescence induced by resveratrol in human endothelial cells.

E. Heiss, V. Dirsch, D. Sorescu, 2009, Free radical biology & medicine.

Chronic Treatment with Resveratrol Induces Redox Stress- and Ataxia Telangiectasia-mutated (ATM)-dependent Senescence in p53-positive Cancer Cells*

E. Heiss, V. Dirsch, Yvonne D C Schilder, 2007, Journal of Biological Chemistry.

AHR/CYP1A1 interplay triggers lymphatic barrier breaching in breast cancer spheroids by inducing 12(S)-HETE synthesis.

Z. Bago-Horvath, W. Jäger, A. Atanasov, 2016, Human Molecular Genetics.

Caco-2 Cells for Measuring Intestinal Cholesterol Transport - Possibilities and Limitations

E. Heiss, V. Dirsch, D. Schachner, 2020, Biological Procedures Online.

Red Wine Polyphenols Enhance Endothelial Nitric Oxide Synthase Expression and Subsequent Nitric Oxide Release From Endothelial Cells

A. Vollmar, V. Dirsch, V. Cheynier, 2002, Circulation.

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells.

A. Vollmar, V. Dirsch, D. Sorescu, 2002, Molecular pharmacology.

Trophosome of the Deep-Sea Tubeworm Riftia pachyptila Inhibits Bacterial Growth

M. Zehl, V. Dirsch, L. Krenn, 2016, PloS one.

Short Chain (≤C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation

E. Heiss, V. Dirsch, Rongxia Liu, 2021, Frontiers in Pharmacology.

Glycolytic Switch in Response to Betulinic Acid in Non-Cancer Cells

A. Atanasov, E. Heiss, V. Dirsch, 2014, PloS one.

12/15-Lipoxygenase Contributes to Platelet-derived Growth Factor-induced Activation of Signal Transducer and Activator of Transcription 3*

Oliver Werz, Elke H. Heiss, Verena M. Dirsch, 2013, The Journal of Biological Chemistry.

In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1

Thierry Langer, Benjamin Kirchweger, Jadel M. Kratz, 2018, Front. Chem..

Revision of the family Pneumoridae lOrthopterac Acridoidear

V. Dirsch, 1965 .

Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK

A. Vollmar, V. Dirsch, M. Kuo, 2003, Oncogene.

Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo

A. Atanasov, E. Heiss, V. Dirsch, 2017, Journal of natural products.

Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation

R. Bauer, A. Atanasov, E. Heiss, 2015, Molecular nutrition & food research.

Caffeic acid phenethyl ester inhibits PDGF-induced proliferation of vascular smooth muscle cells via activation of p38 MAPK, HIF-1α, and heme oxygenase-1.

A. Vollmar, E. Heiss, V. Dirsch, 2011, Journal of natural products.

Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells

A. Atanasov, E. Heiss, V. Dirsch, 2011, Molecular nutrition & food research.

Natural products as modulators of retinoic acid receptor-related orphan receptors (RORs).

V. Dirsch, A. Ladurner, Patrik F Schwarz, 2020, Natural product reports.

Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

A. Atanasov, E. Heiss, V. Dirsch, 2016, Molecular nutrition & food research.

Discovery of New Liver X Receptor Agonists by Pharmacophore Modeling and Shape-Based Virtual Screening

Daniela Schuster, Veronika Temml, Constance V. Voss, 2014, J. Chem. Inf. Model..

Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice.

A. Atanasov, E. Heiss, V. Dirsch, 2021, Journal of natural products.

Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux

A. Atanasov, E. Heiss, V. Dirsch, 2018, Scientific Reports.

Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells.

E. Heiss, V. Dirsch, G. Krupitza, 2011, Mutation research.

Modulation of endothelial nitric oxide by plant-derived products.

V. Dirsch, C. Schmitt, 2009, Nitric oxide : biology and chemistry.

Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1

E. Heiss, V. Dirsch, Cosmin I. Ciotu, 2023, PloS one.

Indirubin-3′-Monoxime Blocks Vascular Smooth Muscle Cell Proliferation by Inhibition of Signal Transducer and Activator of Transcription 3 Signaling and Reduces Neointima Formation In Vivo

A. Atanasov, E. Heiss, V. Dirsch, 2010, Arteriosclerosis, thrombosis, and vascular biology.

The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

R. Bauer, A. Atanasov, E. Heiss, 2017, Front. Pharmacol..

Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages

A. Atanasov, E. Heiss, H. Stuppner, 2016, Journal of Natural Products.

Caco-2 Cells for Measuring Intestinal Cholesterol Transport - Possibilities and Limitations

E. Heiss, V. Dirsch, D. Schachner, 2020, Biological Procedures Online.

Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3′-monoxime

E. Heiss, V. Dirsch, D. Schachner, 2016, Vascular pharmacology.

Effect of resveratrol on endothelial cell function: Molecular mechanisms

E. Heiss, V. Dirsch, C. Schmitt, 2010, BioFactors.

Quantitation of phenylpropanoids and iridoids in insulin-sensitising extracts of Leonurus sibiricus L. (Lamiaceae).

M. Zehl, E. Heiss, V. Dirsch, 2016, Phytochemical analysis : PCA.

Walnut leaf extract inhibits PTP1B and enhances glucose-uptake in vitro.

M. Zehl, A. Atanasov, E. Heiss, 2014, Journal of ethnopharmacology.

TheMarineProductCephalostatin1ActivatesanEndoplasmic ReticulumStress-specificandApoptosome-independent ApoptoticSignalingPathway *

A. Vollmar, V. Dirsch, K. Schulze-Osthoff, 2006 .

Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases

A. Atanasov, E. Heiss, V. Dirsch, 2015, Evidence-based complementary and alternative medicine : eCAM.

Synthesis of Selagibenzophenone A and Its Derivatives for Evaluation of Their Antiproliferative, RORγ Inverse Agonistic, and Antimicrobial Effect**

V. Dirsch, I. Císařová, T. Karpiński, 2023, ChemistrySelect.

Constituents of Mediterranean Spices Counteracting Vascular Smooth Muscle Cell Proliferation: Identification and Characterization of Rosmarinic Acid Methyl Ester as a Novel Inhibitor

A. Atanasov, E. Heiss, H. Stuppner, 2018, Molecular nutrition & food research.

NF-κB Inhibitors from Eurycoma longifolia

A. Atanasov, E. Heiss, H. Stuppner, 2014, Journal of natural products.

Portulaca oleracea, a rich source of polar lipids: Chemical profile by LC-ESI/LTQOrbitrap/MS/MSn and in vitro preliminary anti-inflammatory activity.

A. Napolitano, E. Heiss, V. Dirsch, 2022, Food chemistry.

Piperine Congeners as Inhibitors of Vascular Smooth Muscle Cell Proliferation

A. Atanasov, E. Heiss, J. Rollinger, 2015, Planta Medica.

Modulation of bacterial ghosts – induced nitric oxide production in macrophages by bacterial ghost‐delivered resveratrol

V. Dirsch, W. Lubitz, P. Kúdela, 2013, The FEBS journal.

Linked magnolol dimer as a selective PPARγ agonist – Structure-based rational design, synthesis, and bioactivity evaluation

A. Atanasov, D. Schuster, E. Heiss, 2017, Scientific Reports.

Polyacetylenes from Oplopanax horridus and Panax ginseng: Relationship between Structure and PPARγ Activation

R. Bauer, D. Schuster, V. Dirsch, 2020, Journal of natural products.

The Acridoidea (Orthoptera) of Madagascar. III. Pyrgomorphidae

V. Dirsch, 1963 .

Biochemometry identifies suppressors of pro-inflammatory gene expression in Pterocarpus santalinus heartwood.

J. Rollinger, V. Dirsch, D. Schachner, 2023, Phytochemistry.

Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project

R. Bauer, D. Bernhard, A. Atanasov, 2016, Monatshefte für Chemie - Chemical Monthly.

Identification of Chromomoric Acid C-I as an Nrf2 Activator in Chromolaena odorata

A. Atanasov, E. Heiss, H. Stuppner, 2014, Journal of natural products.

A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.

M. Zehl, G. Ecker, W. Jäger, 2015, Mutation research.

Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation.

A. Vollmar, V. Dirsch, G. Wanner, 2011, Biochemical pharmacology.

Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB.

A. Vollmar, V. Dirsch, A. Gerbes, 1998, Molecular pharmacology.

Resveratrol Blocks Akt Activation in Angiotensin Ii- or Egf-stimulated Vascular Smooth Muscle Cells in a Redox-independent Manner

A. Atanasov, E. Heiss, V. Dirsch, 2022 .

Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo

S. Noha, A. Atanasov, D. Schuster, 2014, British journal of pharmacology.

Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF- κ B Inhibitors

R. Bauer, A. Atanasov, E. Heiss, 2017, Planta Medica.

Effect of resveratrol on endothelial cell function: Molecular mechanisms

E. Heiss, V. Dirsch, C. Schmitt, 2010, BioFactors.

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.

J. Hohmann, T. Szekeres, W. Jäger, 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

J. Hohmann, T. Szekeres, W. Jäger, 2015, Cancer letters.

Evaluation of Apricot, Bilberry, and Elderberry Pomace Constituents and Their Potential To Enhance the Endothelial Nitric Oxide Synthase (eNOS) Activity

M. Zehl, V. Dirsch, B. Kopp, 2018, ACS omega.

Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells.

E. Heiss, V. Dirsch, G. Krupitza, 2011, Mutation research.

Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation.

A. Vollmar, V. Dirsch, G. Wanner, 2011, Biochemical pharmacology.

Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease

V. Dirsch, S. Schwaiger, M. Schnürch, 2019, Chemical science.

G. Ecker, W. Jäger, A. Atanasov, 2015, Mutation research.

Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques

A. Atanasov, D. Schuster, P. Markt, 2011, Bioorganic & medicinal chemistry letters.

Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques

A. Atanasov, D. Schuster, P. Markt, 2011, Bioorganic & medicinal chemistry letters.

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

T. Szekeres, W. Jäger, A. Atanasov, 2013, Archives of Toxicology.