K. Dechering

发表

Distinct frequency-distributions of homopolymeric DNA tracts in different genomes.

J. Leunissen, K. Cuelenaere, K. Dechering, 1998, Nucleic acids research.

Identification of Novel Regulators Associated With Early‐Phase Osteoblast Differentiation

C. Mummery, R. Wehrens, K. Dechering, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1.

M. Reinders, C. V. van Blitterswijk, J. de Boer, 2013, Biomaterials.

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

M. Smid, J. Veldscholte, L. Dorssers, 2004, Breast Cancer Research.

X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11β-Substituted Steroids

R. McGuire, K. Dechering, H. Hamersma, 2012, The Journal of Biological Chemistry.

The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells.

A. Leusink, C. V. van Blitterswijk, J. de Boer, 2009, Tissue engineering. Part A.

Experimental infections of Anopheles gambiae with Plasmodium falciparum of naturally infected gametocyte carriers in Cameroon: factors influencing the infectivity to mosquitoes.

K. Dechering, J. Verhave, J. Meuwissen, 1993, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

K. Dechering, C. Janse, G. van Gemert, 2019, Front. Cell. Infect. Microbiol..

Estrogen Receptors α and β : Two Receptors of a Kind ?

K. Dechering, S. Mosselman, C. Boersma, 2001 .

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

E. R. van den Heuvel, K. Dechering, P. Ducy, 2006, Bone.

A novel multiple-stage antimalarial agent that inhibits protein synthesis

David W. Gray, E. Winzeler, S. Meister, 2015, Nature.

Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators

R. McGuire, K. Dechering, J. de Vlieg, 2011, The Journal of Biological Chemistry.

High-Throughput Assay for the Identification of Compounds Regulating Osteogenic Differentiation of Human Mesenchymal Stromal Cells

C. V. van Blitterswijk, J. de Boer, K. Dechering, 2011, PloS one.

Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum

M. Llinás, P. Jansen, K. Dechering, 2018, bioRxiv.

TSLP is differentially regulated by vitamin D3 and cytokines in human skin

R. de Waal Malefyt, S. Sadekova, K. Dechering, 2015, Immunity, inflammation and disease.

University of Groningen Microarray analysis on Runx 2-deficient mouse embryos reveals novel Runx 2 functions and target genes during intramembranous and endochondral bone formation

K. Dechering, P. Ducy, A. Sijbers, 2017 .

Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers.

K. Dechering, J. Verhave, J. Meuwissen, 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.

David M. Shackleford, Laura M Sanz, K. Dechering, 2021, Journal of medicinal chemistry.

Metabolic activity organizes olfactory representations

Alexander B. Wiltschko, Wesley Wei Qian, Brian K. Lee, 2022, bioRxiv.

Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors

David M. Shackleford, D. Fidock, Laura M Sanz, 2021, ACS infectious diseases.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

S. Croft, T. Bousema, F. Gamo, 2017, Nature Communications.

Detection of PTHrP and Ihh in fetal epiphyseal growth plate zones

K. Dechering, R. V. Donkelaar, 2006 .

Metabolic activity organizes olfactory representations

Alexander B. Wiltschko, Wesley Wei Qian, Brian K. Lee, 2022, bioRxiv.

A deep learning and digital archaeology approach for mosquito repellent discovery

Alexander B. Wiltschko, Wesley Wei Qian, Brian K. Lee, 2022, bioRxiv.

Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission

T. Bousema, H. Duerr, K. Dechering, 2017, Scientific Reports.

A deep learning and digital archaeology approach for mosquito repellent discovery

Alexander B. Wiltschko, Wesley Wei Qian, Brian K. Lee, 2022, bioRxiv.

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate—Tackling the Cocktail Challenge

K. Dechering, S. Schillberg, R. Fischer, 2015, PloS one.

Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected

T. Bousema, C. Drakeley, K. Dechering, 2019 .

Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso

T. Bousema, C. Drakeley, K. Dechering, 2018, Wellcome open research.

Effect of Chordin-Like 1 on MC3T3-E1 and Human Mesenchymal Stem Cells

C. V. van Blitterswijk, J. de Boer, K. Dechering, 2010, Cells Tissues Organs.

A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase.

A. Vaughan, S. Kappe, Nelly Camargo, 2014, Journal of Infectious Diseases.

A small-molecule myosin inhibitor as a targeted multi-stage antimalarial

Paul V. Ruijgrok, E. Winzeler, J. Spudich, 2022, bioRxiv.

Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver

A. Pain, K. Dechering, V. Heussler, 2022, npj Vaccines.

Sphingosine‐1‐phosphate acts as a developmental stage specific inhibitor of platelet‐derived growth factor‐induced chemotaxis of osteoblasts

K. Dechering, R. Akkers, W. Beumer, 2008, Journal of cellular biochemistry.

Identification of Novel Bacterial M.SssI DNA Methyltransferase Inhibitors

K. Dechering, E. J. V. van Zoelen, R. Azevedo, 2013, Journal of biomolecular screening.

A deep learning and digital archaeology approach for mosquito repellent discovery

Alexander B. Wiltschko, Wesley Wei Qian, Brian K. Lee, 2024, bioRxiv.

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.

Silvia Parapini, Donatella Taramelli, Simone Brogi, 2018, European journal of medicinal chemistry.

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Benito Munoz, Stuart L. Schreiber, Takashi Yoshinaga, 2016, Nature.

Ca2+ and Mg2+ transport in gills and gut of tilapia, Oreochromis mossambicus : a review

G. Flik, K. Dechering, Z. Kolar, 1993 .

Salinomycin and Other Ionophores as a New Class of Antimalarial Drugs with Transmission-Blocking Activity

S. Abay, M. Gismondo, S. Parapini, 2015, Antimicrobial Agents and Chemotherapy.

MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells

K. Dechering, J. M. Hendriks, E. J. V. van Zoelen, 2014, BMC Molecular Biology.

Regulation of Notch signaling genes during BMP2-induced differentiation of osteoblast precursor cells.

K. Dechering, W. Steegenga, D. S. de Jong, 2004, Biochemical and biophysical research communications.

DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation.

K. Dechering, E. Piek, E. V. van Someren, 2011, Biochimica et biophysica acta.

Control of gene expression in Plasmodium falciparum.

M Lanzer, K. Dechering, M. Lanzer, 1998, Molecular and biochemical parasitology.

Developmentally regulated expression of pfs16, a marker for sexual differentiation of the human malaria parasite Plasmodium falciparum.

K. Dechering, R. Konings, W. Eling, 1997, Molecular and biochemical parasitology.

Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening

David W. Gray, K. Dechering, D. Gray, 2023, Communications Biology.

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Farah El Mazouni, T. Laird, P. Rathod, 2015, Science Translational Medicine.

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

T. Bousema, K. Dechering, G. van Gemert, 2016, Malaria Journal.

The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable

K. Dechering, B. López-Méndez, C. King, 2019, The Journal of Biological Chemistry.

Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

K. Kuhen, E. Winzeler, S. Meister, 2013, Nature.

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum

M. Llinás, P. Jansen, K. Dechering, 2019, Science Translational Medicine.

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection.

Silvia Parapini, Nicoletta Basilico, Donatella Taramelli, 2013, The Journal of antimicrobial chemotherapy.

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

Peter G. Schultz, Petr Volf, Teun Bousema, 2018, Proceedings of the National Academy of Sciences.

MalDA, Accelerating Malaria Drug Discovery

E. Winzeler, I. Gilbert, K. Chibale, 2021, Trends in parasitology.

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

David M. Shackleford, G. Drewes, M. Bantscheff, 2017, Science Translational Medicine.

Osteo-transcriptomics of human mesenchymal stem cells: accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis.

Christian Gilissen, Susanne Bauerschmidt, Ester Piek, 2010, Bone.

Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor‐Induced Osteoblast Differentiation

K. Dechering, P. ten Dijke, A. Sijbers, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells

C. V. van Blitterswijk, J. de Boer, K. Dechering, 2009, Journal of tissue engineering and regenerative medicine.

Epigenetics: DNA demethylation promotes skeletal myotube maturation

D. Ypey, K. Dechering, E. Piek, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Least absolute regression network analysis of the murine osteoblast differentiation network

Marcel J. T. Reinders, Eugene P. van Someren, B. L. T. Vaes, 2006, Bioinform..

Prioritization of Molecular Targets for Antimalarial Drug Discovery

E. Winzeler, I. Gilbert, M. Siegel, 2021, ACS infectious diseases.

Comprehensive Microarray Analysis of Bone Morphogenetic Protein 2‐Induced Osteoblast Differentiation Resulting in the Identification of Novel Markers for Bone Development

Christine L Mummery, C. Mummery, K. Dechering, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

Teun Bousema, Robert W. Sauerwein, Koen J. Dechering, 2015, Scientific Reports.

Targeting Plasmodium PI(4)K to eliminate malaria

Robert W. Sauerwein, Bruce Russell, David C. Tully, 2013, Nature.

Isolation and Functional Characterization of Two Distinct Sexual-Stage-Specific Promoters of the Human Malaria Parasite Plasmodium falciparum

Koen J. Dechering, Dyann F. Wirth, Hendrik G. Stunnenberg, 1999, Molecular and Cellular Biology.

Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out

M. Segall, K. Dechering, Saman Honarnejad, 2022, bioRxiv.

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

K. Dechering, M. Signore, V. Avery, 2015, Scientific Reports.

Erratum: Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum (Science Translational Medicine DOI: 10.1126/scitranslmed.aas9917)

M. Llinás, P. Jansen, K. Dechering, 2021 .