Lai-Hua Xie

Lai-Hua Xie, Hong-Gang Wang, Zhao Liu, 2015, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Exchange protein directly activated by cyclic AMP increases melanoma cell migration by a Ca2+-dependent mechanism.

M. Nowycky, K. Iwatsubo, Lai-Hua Xie, 2010, Cancer research.

Tumor and Stem Cell Biology Cancer Research Exchange Protein Directly Activated by Cyclic AMP Increases Melanoma Cell Migration by a Ca 2 +-Dependent Mechanism

M. Nowycky, K. Iwatsubo, Lai-Hua Xie, 2010 .

Cardiac adaptation and cardioprotection against arrhythmias and ischemia-reperfusion injury in mammalian hibernators

Lai-Hua Xie, J. Gwathmey, Zhenghang Zhao, 2021, Pflügers Archiv - European Journal of Physiology.

TPEN, a Specific Zn2+ Chelator, Inhibits Sodium Dithionite and Glucose Deprivation (SDGD)-Induced Neuronal Death by Modulating Apoptosis, Glutamate Signaling, and Voltage-Gated K+ and Na+ Channels

Lai-Hua Xie, Hong-Gang Wang, F. Zhang, 2017, Cellular and Molecular Neurobiology.

Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore

Lai-Hua Xie, J. Gwathmey, N. Fefelova, 2020, Antioxidants.

Prevention of Connexin43 remodeling protects against duchenne muscular dystrophy cardiomyopathy.

G. Fishman, Lai-Hua Xie, X. Wehrens, 2020, The Journal of clinical investigation.

Prevention of Connexin 43 remodeling protects against Duchenne muscular 2 dystrophy cardiomyopathy

Lai-Hua Xie, X. Wehrens, D. Fraidenraich, 2019 .

Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility.

M. Nowycky, Lai-Hua Xie, C. Hong, 2011, Cardiovascular research.

Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy.

Lai-Hua Xie, D. Duan, N. Niranjan, 2019, American journal of physiology. Cell physiology.

The properties of the Kir6.1–6.2 tandem channel co-expressed with SUR2A

M. Horie, Lai-Hua Xie, S. Sasayama, 2000, Pflügers Archiv.

The properties of the Kir 6 . 1 – 6 . 2 tandem channel co-expressed with SUR 2 A

M. Horie, Lai-Hua Xie, S. Sasayama, 2022 .

Cardiac alternans in embryonic mouse ventricles.

Mya Mya Thu, J. Weiss, Lai-Hua Xie, 2008, American journal of physiology. Heart and circulatory physiology.

Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling.

Lai-Hua Xie, G. Babu, N. Fefelova, 2011, Journal of molecular and cellular cardiology.

Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload

S. Vatner, Lai-Hua Xie, R. Kitsis, 2012, Basic Research in Cardiology.

Oxidative stress-mediated effects of angiotensin II in the cardiovascular system.

Lai-Hua Xie, J. Gwathmey, Hairuo Wen, 2012, World journal of hypertension.

Selective Connexin43 Inhibition Prevents Isoproterenol-Induced Arrhythmias and Lethality in Muscular Dystrophy Mice

Lai-Hua Xie, D. Fraidenraich, J. Contreras, 2015, Scientific Reports.

Involvement of cytosolic and mitochondrial iron in iron overload cardiomyopathy: an update

N. Chattipakorn, S. Chattipakorn, Lai-Hua Xie, 2018, Heart Failure Reviews.

Inhibition of the cardiac protein kinase A-dependent chloride conductance by endothelin-1

M. Horie, Lai-Hua Xie, A. James, 1994, Nature.

Docosahexaenoic Acid Reduces the Incidence of Early Afterdepolarizations Caused by Oxidative Stress in Rabbit Ventricular Myocytes

Lai-Hua Xie, J. Gwathmey, W. Zang, 2012, Front. Physio..

Docosahexaenoic Acid Reduces the Incidence of Early Afterdepolarizations Caused by Oxidative Stress in Rabbit Ventricular Myocytes

Lai-Hua Xie, J. Gwathmey, W. Zang, 2012, Front. Physio..

Ginsenoside Re: pharmacological effects on cardiovascular system.

Lai-Hua Xie, S. Wicks, Jing-tian Xie, 2012, Cardiovascular therapeutics.

Newly Identified NO‐Sensor Guanylyl Cyclase/Connexin 43 Association Is Involved in Cardiac Electrical Function

Lai-Hua Xie, P. Brouckaert, P. Lampe, 2017, Journal of the American Heart Association.

Microtubule-Connexin-43 regulation suppresses arrhythmias and fibrosis in Duchenne muscular dystrophy mice

Lai-Hua Xie, X. Wehrens, D. Fraidenraich, 2022, bioRxiv.

Increased Oxidative Stress in the Nucleus Caused by Nox4 Mediates Oxidation of HDAC4 and Cardiac Hypertrophy

B. Tian, Lai-Hua Xie, J. Sadoshima, 2013, Circulation research.

Action Potential Duration Restitution and Alternans in Rabbit Ventricular Myocytes: The Key Role of Intracellular Calcium Cycling

Joshua I. Goldhaber, Tan Duong, Lai-Hua Xie, 2005, Circulation research.

Spermine Block of th e Strong Inward Rectifier Potassium Channel Kir2.1: Dual Roles of Surface Charge Screening and Pore Block

S. John, J. Weiss, Lai-Hua Xie, 2002 .

Agonist-independent modulation of L-type Ca currents by basal Gs protein activities in single guinea pig ventricular myocytes

M. Horie, Lai-Hua Xie, S. Sasayama, 2000, Heart and Vessels.

Mitochondrial Ca2+ Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy

Z. Qu, Lai-Hua Xie, Z. Song, 2018, Journal of the American Heart Association.

Transient receptor potential cation 3 channel regulates melanoma proliferation and migration

Y. Yamaguchi, K. Iwatsubo, Y. Ishikawa, 2016, The Journal of Physiological Sciences.

Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.

Lai-Hua Xie, N. Niranjan, G. Babu, 2020, American journal of physiology. Heart and circulatory physiology.

(cid:1) 1 -Adrenoceptor–Mediated Breakdown of Phosphatidylinositol 4,5-Bisphosphate Inhibits Pinacidil-Activated ATP-Sensitive K (cid:2) Currents in Rat Ventricular Myocytes

M. Horie, Lai-Hua Xie, M. Takano, 2002 .

Author ' s response to reviews Title : G betagamma subunits inhibit Epac-induced melanoma cell migration

K. Iwatsubo, Lai-Hua Xie, James S Goydos, 2011 .

Cardiac Specific Expression of Threonine 5 to Alanine Mutant Sarcolipin Results in Structural Remodeling and Diastolic Dysfunction

G. Yehia, Lai-Hua Xie, G. Babu, 2015, PloS one.

Normalization of connexin 43 protein levels prevents cellular and functional signs of dystrophic cardiomyopathy in mice

Lai-Hua Xie, D. Fraidenraich, N. Shirokova, 2018, Neuromuscular Disorders.

Oxygen–glucose deprivation enhancement of cell death/apoptosis in PC12 cells and hippocampal neurons correlates with changes in neuronal excitatory amino acid neurotransmitter signaling and potassium currents

Lai-Hua Xie, Hong-Gang Wang, Yu-xiang Wang, 2016, Neuroreport.

Primary effect of reactive oxygen species on electrical remodeling of the heart.

Lai-Hua Xie, Richard Gordan, 2014, Circulation journal : official journal of the Japanese Circulation Society.

Cardiac adaptation and cardioprotection against arrhythmias and ischemia-reperfusion injury in mammalian hibernators

Lai-Hua Xie, J. Gwathmey, Zhenghang Zhao, 2021, Pflügers Archiv - European Journal of Physiology.

Impaired Autophagy and Mitochondrial Dynamics Are Involved in Sorafenib-Induced Cardiomyocyte Apoptosis.

Lai-Hua Xie, Heqin Zhan, Wenzhuo Ma, 2022, Toxicology.

Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak.

Alan Garfinkel, Zhilin Qu, Daisuke Sato, 2008, Biophysical journal.

Erratum: Synchronization of chaotic early afterdepolar-izations in the genesis of cardiac arrhythmias (Proceedings of the National Academy of Sciences of the United States of America (2009) 106 (2983-2988) DOI:10.1073/pnas. 0809148106)

Alan Garfinkel, Zhilin Qu, James N. Weiss, 2009 .

Molecular Characterization of the Hyperpolarization-activated Cation Channel in Rabbit Heart Sinoatrial Node*

Akinori Noma, Harunori Ohmori, Lai-Hua Xie, 1999, The Journal of Biological Chemistry.

Potential Duration Restitution and Alternans in Rabbit Ventricular Myocytes

J. Weiss, Lai-Hua Xie, K. Khuu, 2005 .

Cellular Electrophysiology of Iron-Overloaded Cardiomyocytes

N. Chattipakorn, S. Chattipakorn, Lai-Hua Xie, 2018, Front. Physiol..

Involvement of mitochondrial permeability transition pore (mPTP) in cardiac arrhythmias: Evidence from cyclophilin D knockout mice.

Lai-Hua Xie, J. Gwathmey, N. Fefelova, 2015, Cell calcium.

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

J. McArdle, J. Mendell, Lai-Hua Xie, 2017, Nature Communications.

Autonomic and endocrine control of cardiovascular function.

Lai-Hua Xie, Lai-Hua Xie, J. Gwathmey, 2015, World journal of cardiology.

Molecular Mechanism for ATP‐Dependent Closure of the K+ Channel Kir6.2

S. John, J. Weiss, Lai-Hua Xie, 2003, The Journal of physiology.

The effects of macrophages on cardiomyocyte calcium‐handling function using in vitro culture models

Lai-Hua Xie, E. Lee, Dominic P Del Re, 2019, Physiological reports.

Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress.

A. Garfinkel, J. Weiss, M. Fishbein, 2009, American journal of physiology. Heart and circulatory physiology.

Electrophysiological Consequences of Acute Regional Ischemia/Reperfusion in Neonatal Rat Ventricular Myocyte Monolayers

Fuhua Chen, Lai-Hua Xie, J. Weiss, 2008, Circulation.

Ablation of sarcolipin results in atrial remodeling.

Lai-Hua Xie, M. Periasamy, Ji Yeon Park, 2012, American journal of physiology. Cell physiology.

Classification of potassium and chlorine ionic currents in retinal ganglion cell line (RGC-5) by whole-cell patch clamp

Lai-Hua Xie, Bin Heng, Yan-qiang Liu, 2012, Visual Neuroscience.

Electroactive graphene composite scaffolds for cardiac tissue engineering.

P. Patra, Lai-Hua Xie, Prabhakar Singh, 2018, Journal of biomedical materials research. Part A.

Store-Operated Ca2 + Entry (SOCE) Regulates Melanoma Proliferation and Cell Migration

K. Iwatsubo, Y. Ishikawa, S. Feske, 2014, PloS one.

Golli protein negatively regulates store depletion-induced calcium influx in T cells.

C. Colwell, A. Campagnoni, Lai-Hua Xie, 2006, Immunity.

The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation

Lai-Hua Xie, Hong-Gang Wang, Jun-Li Duan, 2015, CNS neuroscience & therapeutics.

Role of Transient Receptor Potential Canonical Channels in Heart Physiology and Pathophysiology

Lai-Hua Xie, J. Gwathmey, Hairuo Wen, 2020, Frontiers in Cardiovascular Medicine.

Nitric oxide signalling pathway in Duchenne muscular dystrophy mice: up-regulation of L-arginine transporters.

Lai-Hua Xie, D. Fraidenraich, A. Beuve, 2013, The Biochemical journal.

Calcium and Heart Failure: How Did We Get Here and Where Are We Going?

Lai-Hua Xie, J. Gwathmey, Natthaphat Siri-Angkul, 2021, International journal of molecular sciences.

S-nitrosylation of Connexin43 hemichannels elicits cardiac stress induced arrhythmias in Duchenne Muscular Dystrophy mice.

Lai-Hua Xie, D. Fraidenraich, N. Shirokova, 2019, JCI insight.

Gβγ subunits inhibit Epac-induced melanoma cell migration

M. Nowycky, K. Iwatsubo, Lai-Hua Xie, 2011, BMC Cancer.

Modulation of Intracellular Calcium Waves and Triggered Activities by Mitochondrial Ca Flux in Mouse Cardiomyocytes

Lai-Hua Xie, W. Zang, N. Fefelova, 2013, PloS one.

Potential antiarrhythmic effect of methyl 3,4,5-trimethoxycinnamate, a bioactive substance from roots of polygalae radix: suppression of triggered activities in rabbit myocytes.

Lai-Hua Xie, W. Zang, N. Fefelova, 2013, Biological & pharmaceutical bulletin.

Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents?

Lai-Hua Xie, A. Baba, T. Matsuda, 2011, American journal of physiology. Heart and circulatory physiology.

Arrhythmogenic consequences of intracellular calcium waves.

Lai-Hua Xie, J. Weiss, Lai-Hua Xie, 2009, American journal of physiology. Heart and circulatory physiology.

Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics.

Alan Garfinkel, Zhilin Qu, Daisuke Sato, 2007, Biophysical journal.

The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo

Tristan T. Hays, Lai-Hua Xie, C. Depré, 2017, Scientific Reports.

Giα1-Mediated Cardiac Electrophysiological Remodeling and Arrhythmia in Hypertrophic Cardiomyopathy

Lai-Hua Xie, Yibin Wang, Q. Lou, 2007, Circulation.

CORRECTIONS

Diana X. Tran, R. Coler, H. Karagueuzian, 2019, The Annals of Family Medicine.

‘ Protection of synapses against Alzheimer ’ slinked toxins : Insulin signaling prevents the pathogenic binding of A oligomers

Yasir, Diana X. Tran, R. Coler, 2009 .

Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells.

Lai-Hua Xie, D. Fraidenraich, J. Sadoshima, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells.

Z. Qu, Lai-Hua Xie, P. Boyden, 2012, Cardiovascular research.

Effect of densely ionizing radiation on cardiomyocyte differentiation from human‐induced pluripotent stem cells

Jianyi(Jay) Zhang, Lai-Hua Xie, E. Azzam, 2017, Physiological reports.

The effect of PVDF‐TrFE scaffolds on stem cell derived cardiovascular cells

Lai-Hua Xie, T. Arinzeh, Richard Gordan, 2015, Biotechnology and bioengineering.

A Novel Role for Connexin Hemichannel in Oxidative Stress and Smoking-Induced Cell Injury

R. Lal, S. John, S. Subramaniam, 2007, PloS one.

Abstract 19344: Involvement of Mitochondrial Permeability Transition Pore (mPTP) in Cardiac Arrhythmias: Evidence From Cyclophilin D Knockout Mice

Lai-Hua Xie, N. Fefelova, Richard Gordan, 2015, Circulation.

Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heart.

S. Vatner, Lai-Hua Xie, D. Vatner, 2015, American journal of physiology. Heart and circulatory physiology.

Mitochondrial Contributions in the Genesis of Delayed Afterdepolarizations in Ventricular Myocytes

Z. Qu, Lai-Hua Xie, V. Pandey, 2021, Frontiers in Physiology.

Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2).

S. John, J. Weiss, Lai-Hua Xie, 2005, Journal of molecular and cellular cardiology.

Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands.

S. John, J. Weiss, Lai-Hua Xie, 2007, Progress in biophysics and molecular biology.

S-Nitrosylation of Cx43 Hemichannels Promotes Cardiac Arrhythmias in a Duchene Muscular Dystrophy Mouse Model

Lai-Hua Xie, D. Fraidenraich, J. Contreras, 2019, Biophysical Journal.

Phosphatidylinositol‐4,5‐bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity

S. John, J. Weiss, Lai-Hua Xie, 2008, The Journal of physiology.

Abstract 17445: Overexpression of Adenylyl Cyclase Type 5 (AC5) in the Heart Predisposes to Cardiac Arrhythmias

S. Vatner, K. Iwatsubo, Y. Ishikawa, 2010 .

Abstract 2664: Arrhythmia Protection Insights From a Hibernating Animal

S. Vatner, Lai-Hua Xie, D. Vatner, 2009 .

Activation of TRPC (Transient Receptor Potential Canonical) Channel Currents in Iron Overloaded Cardiac Myocytes

Z. Qu, N. Chattipakorn, S. Chattipakorn, 2021 .

Inward Rectification by Polyamines in Mouse Kir2.1 Channels: Synergy between Blocking Components

S. John, J. Weiss, Lai-Hua Xie, 2003, The Journal of physiology.

Long Polyamines Act as Cofactors in PIP2 Activation of Inward Rectifier Potassium (Kir2.1) Channels

S. John, J. Weiss, Lai-Hua Xie, 2005, The Journal of general physiology.

Spermine Block of the Strong Inward Rectifier Potassium Channel Kir2.1

S. John, J. Weiss, Lai-Hua Xie, 2002, The Journal of general physiology.

Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model

Z. Qu, Lai-Hua Xie, V. Pandey, 2021, PLoS Comput. Biol..

Remodeled Connexin 43 hemichannels alter cardiac excitability and promote arrhythmias

Lai-Hua Xie, D. Fraidenraich, N. Shirokova, 2022, bioRxiv.

Activation of TRPC Channel Currents in Iron Overloaded Cardiac Myocytes.

Z. Qu, N. Chattipakorn, S. Chattipakorn, 2021, Circulation. Arrhythmia and electrophysiology.

The effect of PVDF‐TrFE scaffolds on stem cell derived cardiovascular cells

Lai-Hua Xie, T. Arinzeh, Richard Gordan, 2015, Biotechnology and bioengineering.

Ablation of sarcolipin results in atrial remodeling.

Lai-Hua Xie, M. Periasamy, Ji Yeon Park, 2012, American journal of physiology. Cell physiology.

Ser14 phosphorylation of Bcl-xL mediates compensatory cardiac hypertrophy in male mice

Lai-Hua Xie, J. Sadoshima, P. Zhai, 2023, Nature communications.

Autonomic and endocrine control of cardiovascular function.

Lai-Hua Xie, J. Gwathmey, Richard Gordan, 2015, World journal of cardiology.

Lai-Hua Xie, Hong-Gang Wang, Jun-Li Duan, 2015, CNS neuroscience & therapeutics.

Deficiency of mitochondrial calcium uniporter abrogates iron overload-induced cardiac dysfunction by reducing ferroptosis

N. Chattipakorn, S. Chattipakorn, Lai-Hua Xie, 2023, Basic Research in Cardiology.

Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias

Diana X. Tran, A. Garfinkel, J. Weiss, 2009, Proceedings of the National Academy of Sciences.

Remodeled connexin 43 hemichannels alter cardiac excitability and promote arrhythmias

Lai-Hua Xie, D. Fraidenraich, N. Shirokova, 2023, The Journal of general physiology.

Prevention of cell death by the zinc ion chelating agent TPEN in cultured PC12 cells exposed to Oxygen-Glucose Deprivation (OGD).

Lai-Hua Xie, Hong-Gang Wang, Zhao Liu, 2015, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel

S. John, J. Weiss, Lai-Hua Xie, 2004, The Journal of physiology.