S. Hoehme

发表

Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration

R. Guthke, R. Gebhardt, J. Hengstler, 2014, Hepatology.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Adam S. Hayward, C. Meyer, S. Dooley, 2013, Archives of Toxicology.

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.

U. Hofmann, L. Kuepfer, R. Gebhardt, 2016, Journal of hepatology.

Creation of Three-Dimensional Liver Tissue Models from Experimental Images for Systems Medicine.

J. Hengstler, S. Hoehme, D. Drasdo, 2017, Methods in molecular biology.

Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice

Christian H. Holland, U. Hofmann, S. Dooley, 2021, Hepatology communications.

A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues

P. Van Liedekerke, S. Hoehme, D. Drasdo, 2019, Biomechanics and Modeling in Mechanobiology.

Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy.

R. Gebhardt, J. Hengstler, S. Hoehme, 2020, 2005.09151.

Shape Characterization of Extracted and Simulated Tumor Samples using Topological and Geometric Measures

G. Scheuermann, S. Hoehme, D. Drasdo, 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

TOWARDS MODELING LIVER LOBULE REGENERATION IN 3 D

J. Hengstler, S. Hoehme, D. Drasdo, 2008 .

Guided interactive image segmentation using machine learning and color-based image set clustering

S. Hoehme, D. Drasdo, A. Friebel, 2020, Bioinform..

Quantitative analysis of hepatic macro‐ and microvascular alterations during cirrhogenesis in the rat

W. D. De Vos, P. Segers, S. Hoehme, 2018, Journal of anatomy.

Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling

Adam T. Sampson, P. Kaye, J. Timmis, 2018, Front. Immunol..

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins

J. Hengstler, S. Hoehme, A. Ghallab, 2022, Archives of Toxicology.

The virtual liver: state of the art and future perspectives

S. Dooley, J. Timmer, H. Holzhütter, 2014, Archives of Toxicology.

A multilevel framework to reconstruct anatomical 3D models of the hepatic vasculature in rat livers (vol 230, pg 471, 2017) (corrigendum)

Jan R. Detrez, P. Segers, S. Hoehme, 2017 .

Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis

Jan Böttger, Jan G. Hengstler, Raymond Reif, 2014, Archives of Toxicology.

Model Prediction and Validation of an Order Mechanism Controlling the Spatiotemporal Phenotype of Early Hepatocellular Carcinoma

Jan G. Hengstler, Stefan Hoehme, Dirk Drasdo, 2018, Bulletin of Mathematical Biology.

Adam S. Hayward, C. Meyer, S. Dooley, 2013, Archives of Toxicology.

A cell-based simulation software for multi-cellular systems

Stefan Hoehme, Dirk Drasdo, S. Hoehme, 2010, Bioinform..

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

J. Hengstler, S. Hoehme, A. Ghallab, 2022, Archives of Toxicology.

Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression

Christian H. Holland, T. Luedde, U. Hofmann, 2021, Cells.

Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney

U. Hofmann, P. Boor, L. Kuepfer, 2021, Archives of Toxicology.

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration

Matthias Hermes, Michael Schwarz, Stefan Hoehme, 2010, Proceedings of the National Academy of Sciences.

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A

J. Hengstler, S. Hoehme, A. Ghallab, 2022, Archives of Toxicology.

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

T. Luedde, J. Rahnenführer, A. Canbay, 2022, Journal of hepatology.

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

I. Vignon-Clementel, J. Hengstler, S. Hoehme, 2020, Hepatology.

On the Role of Physics in the Growth and Pattern Formation of Multi-Cellular Systems: What can we Learn from Individual-Cell Based Models?

S. Hoehme, D. Drasdo, M. Block, 2007 .

Unraveling liver complexity from molecular to organ level: challenges and perspectives.

A. Henney, A. Henney, U. Klingmüller, 2015, Progress in biophysics and molecular biology.

The virtual liver: state of the art and future perspectives

Ursula Klingmüller, Jens Timmer, Jan G. Hengstler, 2014, Archives of Toxicology.

Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones

Stefan Hoehme, Dirk Drasdo, S. Hoehme, 2012 .

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy

J. Hengstler, S. Hoehme, D. Drasdo, 2022, iScience.

Digital twin demonstrates regeneration after partial liver hepatectomy to require biomechanical growth control

J. Hengstler, S. Hoehme, D. Drasdo, 2022, iScience.

How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis.

Stefan Hoehme, Jan G Hengstler, Dirk Drasdo, 2014, Journal of hepatology.

Intravital multi-modal flux analysis reveals the transport mechanism of bile acids through hepatic microconduits

I. Vignon-Clementel, J. Hengstler, S. Hoehme, 2019, bioRxiv.

MultiCellDS: a standard and a community for sharing multicellular data

Alexander G. Fletcher, Roeland M. H. Merks, Jacob G. Scott, 2016, bioRxiv.

TiQuant: Software for tissue analysis, quantification and surface reconstruction

Jan G. Hengstler, Stefan Hoehme, Dirk Drasdo, 2014, Bioinform..

Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice

J. Hengstler, S. Hoehme, D. Drasdo, 2010, Histochemistry and Cell Biology.

MultiCellDS: a community-developed standard for curating microenvironment-dependent multicellular data

Alexander G. Fletcher, Roeland M. H. Merks, Jacob G. Scott, 2016, bioRxiv.

Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones

S. Hoehme, D. Drasdo, 2012 .

Biomechanical and Nutrient Controls in the Growth of Mammalian Cell Populations

Stefan Hoehme, Dirk Drasdo, S. Hoehme, 2010 .

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.

U. Hofmann, J. Hampe, R. Gebhardt, 2019, Cell reports.

Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration

R. Guthke, R. Gebhardt, J. Hengstler, 2014, Hepatology.

Genome Analysis

Russ B. Altman, E. Capriotti, S. Hoehme, 2011, Bioinform..

BIOINFORMATICS APPLICATIONS NOTE

S. Hoehme, D. Drasdo, Dirk Drasdo, 2001 .

Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.

S. Hoehme, A. Ghallab, H. Humpf, 2024, Archives of toxicology.

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

I. Vignon-Clementel, J. Hengstler, S. Hoehme, 2020, Hepatology.

BIOINFORMATICS APPLICATIONS NOTE

C. Lottaz, S. Wyman, R. Jansen, 2001 .

Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats.

S. Morad, S. Hoehme, A. Ghallab, 2024, Archives of toxicology.

A predictive computational model shows that biomechanical cell cycle progression control can explain liver regeneration after partial hepatectomy

S. Hoehme, S. Hammad, P. Bucur, 2022 .

Guided interactive image segmentation using machine learning and color-based image set clustering

S. Hoehme, A. Friebel, T. Johann, 2022, Bioinform..