P. Adlard

发表

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

N. Faux, C. Masters, H. Hermjakob, 2010, Proteomics.

The exercise-induced expression of BDNF within the hippocampus varies across life-span

Carl W. Cotman, Paul A. Adlard, Victoria M. Perreau, 2005, Neurobiology of Aging.

Amyloid Imaging in Alzheimer’s Disease and Other Dementias

C. Rowe, C. Masters, K. Pike, 2009, Brain Imaging and Behavior.

Estrogen and exercise interact to regulate brain‐derived neurotrophic factor mRNA and protein expression in the hippocampus

C. Cotman, N. Berchtold, J. Kesslak, 2001, The European journal of neuroscience.

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease.

Kazuhiko Yanai, Nobuyuki Okamura, Christopher C Rowe, 2011, Brain : a journal of neurology.

Characterising the spatial and temporal brain metal profile in a mouse model of tauopathy.

P. Adlard, D. Hare, L. Lago, 2020, Metallomics : integrated biometal science.

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

A. Bush, P. Adlard, J. Duce, 2013, Annals of neurology.

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

A. Bush, P. Adlard, J. Duce, 2014, PloS one.

Parkinson's Disease Iron Deposition Caused by Nitric Oxide-Induced Loss of β-Amyloid Precursor Protein

A. Bush, R. Cherny, P. Adlard, 2015, The Journal of Neuroscience.

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

A. Bush, P. Adlard, R. Cappai, 2017, Molecular Psychiatry.

Three-dimensional atlas of iron, copper, and zinc in the mouse cerebrum and brainstem.

P. Adlard, D. Finkelstein, D. Hare, 2012, Analytical chemistry.

Tau protein: relevance to Parkinson's disease.

Peng Lei, Scott Ayton, Colin L Masters, 2010, The international journal of biochemistry & cell biology.

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

A. Bush, P. Adlard, Y. Haupt, 2017, Redox biology.

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

C. Masters, A. Bush, R. Cherny, 2017, Acta neuropathologica communications.

The effect of dopamine on MPTP-induced rotarod disability

A. Bush, R. Cherny, P. Adlard, 2013, Neuroscience Letters.

Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease

Victoria M Perreau, Paul A Adlard, C. Cotman, 2005, The Journal of Neuroscience.

Copper Modulation as a Therapy for Alzheimer's Disease?

A. Bush, P. Adlard, J. Hidalgo, 2011, International journal of Alzheimer's disease.

Metallothionein-I and -III expression in animal models of Alzheimer disease

C. Cotman, P. Adlard, A. Quintana, 2006, Neuroscience.

Metal chaperones: a novel therapeutic strategy for brain injury?

P. Adlard, D. Finkelstein, P. Crack, 2018, Brain injury.

Improving acquisition times of elemental bio-imaging for quadrupole-based LA-ICP-MS

P. Adlard, D. Finkelstein, P. Doble, 2012 .

High-resolution elemental bioimaging of Ca, Mn, Fe, Co, Cu, and Zn employing LA-ICP-MS and hydrogen reaction gas.

P. Adlard, D. Finkelstein, D. Hare, 2012, Analytical chemistry.

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease.

C. Masters, A. Bush, R. Cherny, 2012, Free radical biology & medicine.

Loss of synaptic Zn2+ transporter function increases risk of febrile seizures

I. Scheffer, V. Wimmer, C. Reid, 2015, Scientific Reports.

The Involvement of Iron in Traumatic Brain Injury and Neurodegenerative Disease

P. Adlard, M. Daglas, 2018, Front. Neurosci..

GSK-3 in Neurodegenerative Diseases

A. Bush, P. Adlard, S. Ayton, 2011, International journal of Alzheimer's disease.

Acute Neurotoxicity Models of Prion Disease.

P. Adlard, D. Finkelstein, V. Lewis, 2018, ACS chemical neuroscience.

Matching sensitivity to abundance: high resolution immuno-mass spectrometry imaging of lanthanide labels and endogenous elements in the murine brain

P. Adlard, Mika T. Westerhausen, S. Funke, 2020 .

Metals and Alzheimer’s Disease: How Far Have We Come in the Clinic?

A. Bush, P. Adlard, 2018, Journal of Alzheimer's disease : JAD.

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe(2+) under physiologically relevant conditions.

A. Bush, P. Adlard, J. Duce, 2014, Biochimica et biophysica acta.

The plasma membrane redox system in Alzheimer's disease

A. Bush, P. Adlard, Ashley I. Bush, 2011, Experimental Neurology.

Exercise-induced gene expression changes in the rat spinal cord.

C. Cotman, V. Perreau, P. Adlard, 2005, Gene expression.

Sequence of cellular changes following localized axotomy to cortical neurons in glia-free culture.

P. Adlard, J. Vickers, T. Dickson, 2000, Journal of neurotrauma.

Metals and Alzheimer's disease.

A. Bush, P. Adlard, 2006, Journal of Alzheimer's disease : JAD.

Redox-active Cu(II)–Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent manner

P. Adlard, L. Shabala, G. Guillemin, 2012, Experimental Neurology.

Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice.

A. Bush, P. Adlard, J. Culvenor, 2016, ACS chemical neuroscience.

Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β1–42-Induced Excess Zn2+ to Functional Zn2+ Deficiency

A. Bush, P. Adlard, A. Takeda, 2018, Molecular Neurobiology.

Metal chaperones prevent zinc-mediated cognitive decline

A. Bush, P. Adlard, S. James, 2015, Neurobiology of Disease.

The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue

C. Masters, A. Bush, R. Cherny, 2014 .

Ceruloplasmin dysfunction and therapeutic potential for Parkinson’s disease

A. Bush, P. Adlard, J. Duce, 2012 .

Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome

A. Bush, P. Adlard, B. Roberts, 2020, International journal of molecular sciences.

Tau pathology, metal dyshomeostasis and repetitive mild traumatic brain injury: an unexplored link paving the way for neurodegeneration.

P. Adlard, M. Daglas, Sydney M A Juan, 2022, Journal of neurotrauma.

PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity.

Blaine R. Roberts, P. Adlard, D. Finkelstein, 2020, Biophysical journal.

Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice

A. Hannan, P. Adlard, Shanshan Li, 2021, Brain Structure and Function.

S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau.

A. Bush, P. Adlard, K. Barnham, 2020, Journal of Alzheimer's disease : JAD.

Neuron‐glia communication: metallothionein expression is specifically up‐regulated by astrocytes in response to neuronal injury

P. Adlard, J. Vickers, R. Chung, 2003, Journal of neurochemistry.

P.044 Effects of exercise and environmental enrichment in serotonin transporter knock-out mice

L. Lanfumey, P. Adlard, J. Nithianantharajah, 2019, European Neuropsychopharmacology.

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

Blaine R. Roberts, P. Adlard, D. Finkelstein, 2019, PLoS pathogens.

ATH434 Rescues Pre-motor Hyposmia in a Mouse Model of Parkinsonism

A. Bush, P. Adlard, D. Finkelstein, 2022, Neurotherapeutics.

Altered amyloid precursor protein, tau‐regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1 month following repetitive mild traumatic brain injury

P. Adlard, M. Daglas, Sydney M A Juan, 2022, The European journal of neuroscience.

Ferroptosis and cell death mechanisms in Parkinson's disease

A. Bush, P. Adlard, D. Finkelstein, 2017, Neurochemistry International.

Characterization of the role of metallothionein-3 in an animal model of Alzheimer’s disease

A. Bush, P. Adlard, Gabriele Meloni, 2012, Cellular and Molecular Life Sciences.

Zn-DTSM, A Zinc Ionophore with Therapeutic Potential for Acrodermatitis Enteropathica?

A. Bush, P. Adlard, I. Volitakis, 2019, Nutrients.

Clioquinol Synergistically Augments Rescue by Zinc Supplementation in a Mouse Model of Acrodermatitis Enteropathica

A. Bush, P. Adlard, R. D. De Lisle, 2013, PLoS ONE.

Pseudomonas aeruginosa as a cause of infectious diarrhoea

S. M. Kirov, P. Adlard, K. Sanderson, 1998, Epidemiology and Infection.

Deferiprone attenuates neuropathology and improves outcome following traumatic brain injury

P. Adlard, S. Rao, M. Daglas, 2022, British journal of pharmacology.

Targeting metals rescues the phenotype in an animal model of tauopathy.

A. Bush, R. Cherny, P. Adlard, 2018, Metallomics : integrated biometal science.

Alzheimer risk factors age and female sex induce cortical Aβ aggregation by raising extracellular zinc

Á. Hunya, A. Bush, P. Adlard, 2020, Molecular Psychiatry.

Metal Ionophore Treatment Restores Dendritic Spine Density and Synaptic Protein Levels in a Mouse Model of Alzheimer's Disease

A. Bush, P. Adlard, R. Cappai, 2011, PloS one.

Cognitive Loss in Zinc Transporter-3 Knock-Out Mice: A Phenocopy for the Synaptic and Memory Deficits of Alzheimer's Disease?

A. Bush, P. Adlard, D. Finkelstein, 2010, The Journal of Neuroscience.

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

C. Masters, R. Tanzi, A. Bush, 2008, Neuron.

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

A. Bush, P. Adlard, D. Finkelstein, 2015, Neurobiology of Disease.

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

David M. Shackleford, C. Masters, A. Bush, 2017, Acta neuropathologica communications.

Zinc Signal in Brain Diseases

P. Adlard, S. Portbury, 2017, International journal of molecular sciences.

Deferiprone Treatment in Aged Transgenic Tau Mice Improves Y-Maze Performance and Alters Tau Pathology

P. Adlard, D. Finkelstein, G. McColl, 2021, Neurotherapeutics.

Zinc and copper modulate Alzheimer Aβ levels in human cerebrospinal fluid

K. Blennow, L. Launer, A. Bush, 2009, Neurobiology of Aging.

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Blaine R. Roberts, G. Egan, A. Bush, 2012, Nature Medicine.

Trehalose elevates brain zinc levels following controlled cortical impact in a mouse model of traumatic brain injury.

P. Adlard, D. Finkelstein, D. Hare, 2018, Metallomics : integrated biometal science.

Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3R451C Mouse Model of Autism

A. Hannan, M. Glass, P. Adlard, 2018, Front. Cell. Neurosci..

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

P. Adlard, D. Finkelstein, S. Hancock, 2014, Front. Aging Neurosci..

The Clinical Implications of Impaired Zinc Signaling in the Brain

A. Bush, P. Adlard, S. Hancock, 2014 .

Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration

P. Adlard, Shalini S Rao, 2018, Front. Mol. Neurosci..

Altered Expression of ZnT10 in Alzheimer's Disease Brain

P. Adlard, D. Ford, H. Bosomworth, 2013, PloS one.

Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology.

Blaine R. Roberts, P. Adlard, D. Finkelstein, 2019, Metallomics : integrated biometal science.

Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro

S. Miescher, P. Adlard, L. Fabri, 2013, PloS one.

Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.

Lesley Cheng, A. Hill, P. Adlard, 2018, ACS chemical neuroscience.

Altered Expression of ZnT 10 in Alzheimer ’ s Disease Brain

P. Adlard, D. Ford, H. Bosomworth, 2013 .

In Vitro Characterization of Pittsburgh Compound-B Binding to Lewy Bodies

C. Rowe, C. Masters, P. Adlard, 2007, The Journal of Neuroscience.

The Alzheimer’s therapeutic PBT2 promotes amyloid‐β degradation and GSK3 phosphorylation via a metal chaperone activity

C. Masters, A. Bush, R. Cherny, 2011, Journal of neurochemistry.

The Long Isoform of Intersectin-1 Has a Role in Learning and Memory

P. Adlard, D. Finkelstein, Yong Yu, 2020, Frontiers in Behavioral Neuroscience.

Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau

C. Masters, A. Hubbard, S. Melov, 2007, PloS one.

Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease

P. Adlard, Juliet M. Taylor, P. Crack, 2014, Neurobiology of Aging.

Fibrillar α-synuclein toxicity depends on functional lysosomes.

A. Bush, P. Adlard, D. Finkelstein, 2020, The Journal of biological chemistry.

The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise

C. Cotman, V. Perreau, P. Adlard, 2004, Neuroscience Letters.

Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation

C. Masters, A. Bush, R. Cherny, 2009, Proceedings of the National Academy of Sciences.

Increasing Cu bioavailability inhibits A beta oligomers and tau phosphorylation

C. Masters, A. Bush, R. Cherny, 2009 .

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease

A. Bush, R. Cherny, P. Adlard, 2014, Molecular Neurodegeneration.

Preferential Neurodegeneration in the Dentate Gyrus by Amyloid β1–42-Induced Intracellular Zn2+Dysregulation and Its Defense Strategy

A. Bush, P. Adlard, A. Takeda, 2019, Molecular Neurobiology.

Interactions of metals and Apolipoprotein E in Alzheimer’s disease

P. Adlard, D. Finkelstein, He Xu, 2014, Front. Aging Neurosci..

GSK-3 in Parkinson ’ s Disease

A. Bush, P. Adlard, S. Ayton, 2011 .

Pharmacotherapeutic targets in Alzheimer's disease

C. Masters, A. Bush, P. Adlard, 2008, Journal of cellular and molecular medicine.

Manuscript in preparation : I . Aging in Rats Promotes Alzheimer ’ s Disease β-amyloid Aggregation and Toxicity by Metallostasis of Extraneuronal Zinc

Blaine R. Roberts, C. Masters, G. Juhász, 2012 .

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species

Blaine R. Roberts, P. Adlard, D. Finkelstein, 2018, PLoS pathogens.

In vivo prion models and the disconnection between transmissibility and neurotoxicity

P. Adlard, D. Finkelstein, V. Lewis, 2017, Ageing Research Reviews.

An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Blaine R. Roberts, C. Masters, A. Bush, 2014 .

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.

P. Adlard, D. Finkelstein, D. Hare, 2013, Metallomics : integrated biometal science.

Trehalose improves traumatic brain injury-induced cognitive impairment

P. Adlard, D. Finkelstein, D. Hare, 2017, PloS one.

Age modulates the injury-induced metallomic profile in the brain.

P. Adlard, D. Finkelstein, D. Hare, 2017, Metallomics : integrated biometal science.

A time-course analysis of changes in cerebral metal levels following a controlled cortical impact.

P. Adlard, D. Finkelstein, D. Hare, 2016, Metallomics : integrated biometal science.

Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer's Disease: Common Pathologies Potentiated by Altered Zinc Homeostasis.

P. Adlard, S. Portbury, 2015, Journal of Alzheimer's disease : JAD.

Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer’s Disease

P. Adlard, D. Finkelstein, D. Hare, 2017, Journal of Alzheimer's disease : JAD.

l‐3,4‐dihydroxyphenylalanine (l‐DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha‐synuclein mouse models of Parkinson's disease

A. Bush, P. Adlard, D. Finkelstein, 2019, Journal of neurochemistry.

Alzheimer’s disease—a sum greater than its parts?

Brian J Cummings, P. Adlard, 2004, Neurobiology of Aging.

Novel zinc-targeted therapeutic options for cognitive decline

P. Adlard, S. Portbury, L. F. Yévenes, 2015 .

Tg2576 Cortical Neurons That Express Human Ab Are Susceptible to Extracellular Aβ-Induced, K+ Efflux Dependent Neurodegeneration

P. Adlard, L. Shabala, G. Guillemin, 2011, PloS one.

Stabilization of Nontoxic Aβ-Oligomers: Insights into the Mechanism of Action of Hydroxyquinolines in Alzheimer's Disease

Blaine R. Roberts, C. Masters, P. Adlard, 2015, The Journal of Neuroscience.

The cause of neuronal degeneration in Alzheimer's disease

P. Adlard, G. McCormack, J. Vickers, 2000, Progress in Neurobiology.

beta-Amyloid as a molecular therapeutic target in Alzheimer's disease.

C. Masters, A. Bush, P. Adlard, 2009, Drugs of Today.

Metal Chaperones: A Holistic Approach to the Treatment of Alzheimer’s Disease

A. Bush, P. Adlard, 2012, Front. Psychiatry.

Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes.

A. Bush, V. Perreau, P. Adlard, 2016, Journal of Alzheimer's disease : JAD.

Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way

R. Martins, A. Bush, P. Adlard, 2015, Neurobiology of Disease.

In vivo synaptic activity-independent co-uptakes of amyloid β1–42 and Zn2+ into dentate granule cells in the normal brain

A. Bush, P. Adlard, A. Takeda, 2019, Scientific Reports.

A novel approach to rapidly prevent age-related cognitive decline

A. Bush, R. Cherny, P. Adlard, 2013, Aging cell.

A review of β-amyloid neuroimaging in Alzheimer's disease

Gary F. Egan, Leigh A. Johnston, Patricia M. Desmond, 2014, Front. Neurosci..

18 F-THK 523 : a novel in vivo tau imaging ligand for Alzheimer ’ s disease

Kazuhiko Yanai, Nobuyuki Okamura, Colin L. Masters, 2011 .

Fibrillar α-synuclein toxicity depends on functional lysosomal.

A. Bush, P. Adlard, D. Finkelstein, 2020, The Journal of biological chemistry.

Iron is increased in the brains of ageing mice lacking the neurofilament light gene

P. Adlard, G. McCormack, J. Vickers, 2019, PloS one.

Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia.

A. Bush, P. Adlard, A. Takeda, 2016, The Journal of toxicological sciences.

Evaluation of attention in APP/PS1 mice shows impulsive and compulsive behaviours

Emma L. Burrows, P. Adlard, L. Churilov, 2019, Genes, brain, and behavior.

Abstracts of the 16th Annual Meeting of The Israel Society for Neuroscience Eilat, Israel, November 25–27, 2007

Yonina C. Eldar, Karl J. Friston, Leslie G. Ungerleider, 2008, Neural plasticity.

Pramipexole restores depressed transmission in the ventral hippocampus following MPTP-lesion

P. Adlard, D. Finkelstein, J. Castro-Hernandez, 2017, Scientific Reports.

Zinc in Alzheimer's and Parkinson's Diseases

A. Bush, R. Cherny, P. Adlard, 2013 .

Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington’s Disease

A. Hannan, A. Bush, P. Adlard, 2019, Neurotherapeutics.

Metallothionein and brain inflammation

P. Adlard, J. Hidalgo, Y. Manso, 2011, JBIC Journal of Biological Inorganic Chemistry.

The effects of enhanced zinc on spatial memory and plaque formation in transgenic mice.

P. Adlard, J. Flinn, D. H. Linkous, 2009, Journal of Alzheimer's disease : JAD.

Therapeutic intervention in Alzheimer's disease

P. Adlard, 2000 .

Rhenium and technetium complexes that bind to amyloid-β plaques.

P. Adlard, H. Tochon-Danguy, V. Villemagne, 2015, Dalton transactions.

Increased Density of Metallothionein I/II-Immunopositive Cortical Glial Cells in the Early Stages of Alzheimer's Disease

P. Adlard, J. Vickers, A. West, 1998, Neurobiology of Disease.

Mild stress facilitates learning and exercise improves retention in aged mice

Carl W. Cotman, Paul A. Adlard, Christie Engesser-Cesar, 2011, Experimental Gerontology.

The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy.

A. Bush, P. Adlard, L. Lago, 2020, Journal of Alzheimer's disease : JAD.

Zinc in Neurodegeneration

A. Bush, P. Adlard, S. Portbury, 2019, Zinc Signaling.

The Role of the Plasma Membrane Redox System in the Pathogenesis of Alzheimer’s Disease

A. Bush, P. Adlard, D. Finkelstein, 2013 .

Characterization of the role of the antioxidant proteins metallothioneins 1 and 2 in an animal model of Alzheimer’s disease

A. Bush, P. Adlard, J. Hidalgo, 2012, Cellular and Molecular Life Sciences.

Adrenergic β receptor activation in the basolateral amygdala, which is intracellular Zn2+-dependent, rescues amyloid β1-42-induced attenuation of dentate gyrus LTP

A. Bush, Miki Suzuki, P. Adlard, 2018, Neurochemistry International.

Role of metal ions in the cognitive decline of Down syndrome

P. Adlard, D. Finkelstein, M. Pritchard, 2014, Front. Aging Neurosci..

Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression

C. Cotman, P. Adlard, 2004, Neuroscience.

Iron, Copper, and Zinc Concentration in Aβ Plaques in the APP/PS1 Mouse Model of Alzheimer's Disease Correlates with Metal Levels in the Surrounding Neuropil.

M. D. de Jonge, P. Adlard, S. James, 2017, ACS chemical neuroscience.

Multivariate Autoregressive-based Neuronal Network Flow Analysis for In-vitro Recorded Bursts

Saeid Nahavandi, Imali Hettiarachchi, Asim Bhatti, 2015, ICONIP.

Amyloid β1–42-Induced Rapid Zn2+ Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia

A. Bush, P. Adlard, A. Takeda, 2018, Molecular Neurobiology.

Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β1–42-Induced Excess Zn2+ to Functional Zn2+ Deficiency

A. Bush, P. Adlard, A. Takeda, 2018, Molecular Neurobiology.

Amyloid β-Mediated Zn2+ Influx into Dentate Granule Cells Transiently Induces a Short-Term Cognitive Deficit

A. Bush, P. Adlard, A. Takeda, 2014, PloS one.

Extracellular Zn2+ Is Essential for Amyloid β1–42-Induced Cognitive Decline in the Normal Brain and Its Rescue

A. Bush, P. Adlard, H. Kanazawa, 2017, The Journal of Neuroscience.

Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease

P. Adlard, O. Shimoni, D. Bishop, 2023, Cells.

Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.

C. Masters, P. Adlard, R. Cappai, 2013, Angewandte Chemie.

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse.

A. Bush, R. Cherny, P. Adlard, 2016, ACS Chemical Neuroscience.

Ageing and Cognition.

P. Adlard, Sydney M A Juan, 2019, Sub-cellular biochemistry.

Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington’s Disease

A. Hannan, A. Bush, P. Adlard, 2019, Neurotherapeutics.

Role of amyloid-β–metal interactions in Alzheimer’s disease

A. Bush, P. Adlard, J. Duce, 2011 .

High order W02-reactive stable oligomers of amyloid-β are produced in vivo and in vitro via dialysis and filtration of synthetic amyloid-β monomer.

C. Masters, A. Bush, R. Cherny, 2015, Journal of Alzheimer's disease : JAD.

Metal Ions and Alzheimer's Disease

A. Bush, P. Adlard, 2007 .

Difference in ability for extracellular Zn2+ influx between human and rat amyloid β1-42 and its significance.

A. Bush, P. Adlard, A. Takeda, 2019, Neurotoxicology.

The Compound ATH434 Prevents Alpha-Synuclein Toxicity in a Murine Model of Multiple System Atrophy

R. Cherny, P. Adlard, N. Stefanova, 2021, Journal of Parkinson's disease.

Spatial memory deficits in a mouse model of late-onset Alzheimer’s disease are caused by zinc supplementation and correlate with amyloid-beta levels

P. Adlard, J. Flinn, Angela M. Railey, 2014, Front. Aging Neurosci..

Amyloid β1–42-Induced Rapid Zn2+ Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia

A. Bush, P. Adlard, A. Takeda, 2018, Molecular Neurobiology.

Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging

P. Adlard, J. Vickers, T. Dickson, 2009, Neurobiology of Aging.

Zinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluid.

K. Blennow, L. Launer, A. Bush, 2009, Neurobiology of aging.

Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain.

Philip Doble, Paul A Adlard, Ashley I Bush, 2010, Metallomics : integrated biometal science.

Morphologically distinct plaque types differentially affect dendritic structure and organisation in the early and late stages of Alzheimer's disease

P. Adlard, J. Vickers, 2002, Acta Neuropathologica.

ATH434 Reverses Colorectal Dysfunction in the A53T Mouse Model of Parkinson’s Disease

R. Cherny, P. Adlard, J. Furness, 2021, Journal of Parkinson's disease.

Abstracts of the 16th Annual Meeting of The Israel Society for Neuroscience Eilat, Israel, November 25–27, 2007

Yonina C. Eldar, Karl J. Friston, Leslie G. Ungerleider, 2008, Neural plasticity.

Isoflurane in the Aged Brain: A Link to Altered Amyloid Precursor Protein Processing

Timothy J. H. Lovell, P. Adlard, D. Finkelstein, 2015 .

The effects of taxol on the central nervous system response to physical injury

P. Adlard, J. Vickers, C. King, 2000, Acta Neuropathologica.

Early perceptual loss in depression

Yonina C. Eldar, Karl J. Friston, Charles R. Seger, 2007 .

Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene

L. Lanfumey, A. Hannan, P. Adlard, 2019, British journal of pharmacology.

Neuronal Response To Physical Injury And Its Relationship To The Pathology Of Alzheimer’s Disease

P. Adlard, Ce King, T. Dickson, 2000, Clinical and experimental pharmacology & physiology.

Parkinson'sDiseaseIronDepositionCausedbyNitricOxide- InducedLossof-AmyloidPrecursorProtein

P. Adlard, 2015 .

β-amyloid in biological samples: not all Aβ detection methods are created equal

C. Masters, A. Bush, P. Adlard, 2014, Front. Aging Neurosci..

Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease.

J. Delgado-García, A. Bush, P. Adlard, 2016, Journal of Alzheimer's disease : JAD.

Editorial: The molecular pathology of cognitive decline: focus on metals

P. Adlard, R. Chung, 2015, Frontiers in Aging Neuroscience.

In vivo synaptic activity-independent co-uptakes of amyloid β1–42 and Zn2+ into dentate granule cells in the normal brain

A. Bush, P. Adlard, A. Takeda, 2019, Scientific Reports.

Adrenergic β receptor activation reduces amyloid β1-42-mediated intracellular Zn2+ toxicity in dentate granule cells followed by rescuing impairment of dentate gyrus LTP.

A. Bush, P. Adlard, A. Takeda, 2020, Neurotoxicology.

Tailored behavioural tests reveal early and progressive cognitive deficits in M1000 prion disease

J. Kim, P. Adlard, D. Finkelstein, 2023, Neurobiology of Disease.

Extracellular Zn2+-independently attenuated LTP by human amyloid β1-40 and rat amyloid β1-42.

A. Bush, P. Adlard, A. Takeda, 2019, Biochemical and biophysical research communications.

Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injury

P. Adlard, M. Daglas, C. Mawal, 2023, Acta Neuropathologica Communications.

Characterization of the role of metallothionein-3 in an animal model of Alzheimer’s disease

A. Bush, P. Adlard, Gabriele Meloni, 2012, Cellular and Molecular Life Sciences.

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice

P. Kwan, C. Hovens, A. Bush, 2017, Epilepsia.

Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Aβ-bearing fragment is associated with reduced NMDA receptor density

C. Masters, A. Bush, P. Adlard, 2010, Behavioural Brain Research.

Delivery of Fluorescent Nanoparticles to the Brain

Olga Shimoni, Bingyang Shi, Paul A Adlard, 2016, Journal of Molecular Neuroscience.

beta-Amyloid as a molecular therapeutic target in Alzheimer's disease.

C. Masters, A. Bush, P. Adlard, 2009, Drugs of today.

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

P. Adlard, J. Duce, S. Ayton, 2013, Annals of neurology.

Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way

R. Martins, A. Bush, P. Adlard, 2015, Neurobiology of Disease.

Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation

C. Masters, A. Bush, R. Cherny, 2009, Proceedings of the National Academy of Sciences.

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

N. Faux, C. Masters, H. Hermjakob, 2010, Proteomics.

Metal chaperones prevent zinc-mediated cognitive decline

A. Bush, P. Adlard, S. James, 2015, Neurobiology of Disease.

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.

P. Adlard, D. Finkelstein, D. Hare, 2013, Metallomics : integrated biometal science.

Acute Neurotoxicity Models of Prion Disease.

P. Adlard, V. Lewis, S. Biggi, 2018, ACS chemical neuroscience.

The Alzheimer’s therapeutic PBT2 promotes amyloid‐β degradation and GSK3 phosphorylation via a metal chaperone activity

C. Masters, A. Bush, R. Cherny, 2011, Journal of neurochemistry.