P. Eikelenboom

发表

C. Plata-salamán, C. Finch, H. Hampel, 2000, Neurobiology of Aging.

Inflammation in older subjects with early- and late-onset depression in the NESDO study: a cross-sectional and longitudinal case-only design

R. Veerhuis, P. Eikelenboom, M. Rozing, 2019, Psychoneuroendocrinology.

Morphometric changes in the cortical microvascular network in Alzheimer's disease.

P. Eikelenboom, E. Richard, W. V. van Gool, 2010, Journal of Alzheimer's disease : JAD.

The structure of the geriatric depressed brain and response to electroconvulsive therapy

P. Scheltens, F. Barkhof, W. Flier, 2014, Psychiatry Research: Neuroimaging.

Association of vascular factors with apathy in community-dwelling elderly individuals.

P. Eikelenboom, E. Richard, W. V. van Gool, 2012, Archives of general psychiatry.

Low-grade inflammation differentiates between symptoms of apathy and depression in community-dwelling older individuals

P. Eikelenboom, E. Richard, W. V. van Gool, 2014, International Psychogeriatrics.

The mediating role of cardiovascular risk factors in the relationship between symptoms of apathy and incident cardiovascular disease in community-dwelling older individuals

J. Jaccard, P. Eikelenboom, E. Richard, 2015, International Psychogeriatrics.

The significance of neuroinflammation in understanding Alzheimer’s disease

W. Scheper, R. Veerhuis, P. Eikelenboom, 2006, Journal of Neural Transmission.

Value of Neuropsychological Tests, Neuroimaging, and Biomarkers for Diagnosing Alzheimer's Disease in Younger and Older Age Cohorts

B. Schmand, P. Eikelenboom, W. V. van Gool, 2011, Journal of the American Geriatrics Society.

Early symptoms in the prodromal phase of delirium: a prospective cohort study in elderly patients undergoing hip surgery.

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2007, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Do Delirium and Alzheimer’s Dementia Share Specific Pathogenetic Mechanisms?

P. Eikelenboom, W. Hoogendijk, 1999, Dementia and Geriatric Cognitive Disorders.

How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes

R. Veerhuis, P. Eikelenboom, I. Blasko, 2004, Aging cell.

Head trauma and Alzheimer's disease.

P. Scheltens, P. Eikelenboom, Rishi D S Nandoe, 2002, Journal of Alzheimer's disease : JAD.

Insulin-like growth factor–1 and risk of late-onset Alzheimer's disease: findings from a family study

M. Stek, P. Eikelenboom, R. Westendorp, 2014, Neurobiology of Aging.

Early complement components in Alzheimer's disease brains

R. Veerhuis, P. Eikelenboom, C. Hack, 1995, Acta Neuropathologica.

Inhibitory effect of minocycline on amyloid β fibril formation and human microglial activation

R. Veerhuis, R. Boshuizen, A. Familian, 2006, Glia.

Early age at menopause is associated with increased risk of dementia and mortality in women with Down syndrome.

A. Janssens, C. V. van Duijn, P. Eikelenboom, 2010, Journal of Alzheimer's disease : JAD.

Role of microglia in plaque formation in senile dementia of the Alzheimer type

P. Eikelenboom, F. Stam, J. Rozemuller, 1986, Virchows Archiv. B, Cell pathology including molecular pathology.

Role and regulation of early complement activation products in Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, F. L. Muiswinkel, 2001 .

Distribution of beta amyloid associated proteins in plaques in Alzheimer's disease and in the non-demented elderly.

W. Kamphorst, R. Veerhuis, P. Eikelenboom, 1995, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.

Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3

R. Veerhuis, P. Eikelenboom, P. Valk, 2004, Virchows Archiv.

Complement C4 phenotypes in dementia of the Alzheimer type.

P. Eikelenboom, G. Hauptmann, J. Goetz, 1988, Human heredity.

Neuroinflammation and Alzheimer disease: clinical and therapeutic implications.

R. Veerhuis, P. Eikelenboom, W. V. van Gool, 2000, Alzheimer disease and associated disorders.

Distribution pattern and functional state of α1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease

P. Eikelenboom, F. Stam, J. Abbink, 1991, Acta Neuropathologica.

Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease

W. Kamphorst, P. Eikelenboom, P. Valk, 1994, Virchows Archiv.

Differences between the pathogenesis of senile plaques and congophilic angiopathy in Alzheimer disease.

M. Verbeek, P. Eikelenboom, R. D. de Waal, 1997, Journal of neuropathology and experimental neurology.

[Increased activity of stress-regulating systems in Alzheimer disease].

W. Kamphorst, D. Swaab, P. Eikelenboom, 2001, Tijdschrift voor gerontologie en geriatrie.

C3 and haptoglobin polymorphism in dementia of the Alzheimer type

P. Eikelenboom, W. Jansen, J. Pronk, 1984, Acta psychiatrica Scandinavica.

Costimulatory Effects of Interferon-γ and Interleukin-1β or Tumor Necrosis Factor α on the Synthesis of Aβ1-40 and Aβ1-42 by Human Astrocytes

R. Veerhuis, P. Eikelenboom, I. Blasko, 2000, Neurobiology of Disease.

Interleukin-1β induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2001, Experimental Gerontology.

P0334 - Long-term cognitive outcome of delirium in elderly hip-surgery patients

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2008, European Psychiatry.

Microglia in Diffuse Plaques in Hereditary Cerebral Hemorrhage with Amyloidosis (Dutch). An Immunohistochemical Study

R. Roos, P. Eikelenboom, A. Rozemuller, 1994, Journal of neuropathology and experimental neurology.

Characterization of lymphoid and nonlymphoid cells in the white pulp of the spleen using immunohistoperoxidase techniques and enzyme-histochemistry

P. Eikelenboom, N. Rooijen, D. Boorsma, 1985, Experientia.

Reasons for psychiatric consultation referrals in Dutch nursing home patients with dementia: a comparison with normative data on prevalence of neuropsychiatric symptoms

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2008, International journal of geriatric psychiatry.

Soothing the inflamed brain: effect of non-steroidal anti-inflammatory drugs on Alzheimer's disease pathology.

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2011, CNS & neurological disorders drug targets.

Cerebral amyloid plaques in Alzheimer’s disease but not in scrapie-affected mice are closely associated with a local inflammatory process

H. Fraser, P. Eikelenboom, F. Stam, 1991, Virchows Archiv. B, Cell pathology including molecular pathology.

Neuroinflammation and Alzheimer’s Disease

P. Eikelenboom, 1997 .

Do Nonsteroidal Anti-Inflammatory Drugs Have a Protective Effect Against Dementia?

P. Eikelenboom, F. L. Muiswinkel, 1996, Drugs & aging.

Lack of evidence for dysfunction of the blood-brain barrier in Alzhiemer's disease: An immunohistochemical study

W. Kamphorst, P. Eikelenboom, F. Stam, 1988, Neurobiology of Aging.

Haloperidol Prophylaxis for Elderly Hip‐Surgery Patients at Risk for Delirium: A Randomized Placebo‐Controlled Study

P. Eikelenboom, J. D. de Jonghe, W. V. van Gool, 2005, Journal of the American Geriatrics Society.

Mortality associated with delirium after hip-surgery: a 2-year follow-up study.

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2011, Age and ageing.

The histogenesis of lymph nodes in rat and rabbit

P. Eikelenboom, J. Versteeg, H. L. Langevoort, 1978, The Anatomical record.

Biological clocks in development, aging and Alzheimer's disease

M. Mirmiran, D. Swaab, P. Eikelenboom, 1989 .

No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice

H. Fraser, P. Eikelenboom, J. Scott, 1987, Virchows Archiv. B, Cell pathology including molecular pathology.

Neurones treated with cyclo-oxygenase-1 inhibitors are resistant to amyloid-&bgr;1-42

R. Veerhuis, P. Eikelenboom, Alun Williams, 2003, Neuroreport.

PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie‐infected mice

H. Fraser, P. Eikelenboom, G. Kraal, 1992, The Journal of pathology.

Immune complex-trapping cells in the spleen of the chicken

P. Eikelenboom, N. Rooijen, F. Kroese, 1983, Cell and Tissue Research.

The development of IgM- and IgG-containing plasmablasts in the white pulp of the spleen after stimulation with a thymus-independent antigen (LPS) and a thymus-dependent antigen (SRBC)

P. Eikelenboom, N. Rooijen, D. Boorsma, 1982, Cell and Tissue Research.

The development of specific antibody‐containing cells in the spleen of rabbits during the secondary immune response against free or liposome‐associated albumin antigen

P. Eikelenboom, N. Van Rooijen, N. Kors, 1984, The Anatomical record.

The development of specific antibody‐containing cells and the localization of extracellular antibody in the follicles of the spleen of rabbits after administration of free or liposome‐associated albumin antigen

P. Eikelenboom, N. Van Rooijen, N. Rooijen, 1983 .

Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E2

J. Langeveld, R. Veerhuis, R. Boshuizen, 2002, Brain Research.

Neuroinflammation in delirium: a postmortem case-control study.

A. Zwinderman, E. Aronica, P. Eikelenboom, 2011, Rejuvenation research.

The Blood-Brain Barrier in Cerebral Amyloidogenesis in Alzheimer’s Disease and Scrapie

H. Fraser, P. Eikelenboom, F. Stam, 1988 .

Characterization of non-lymphoid cells in the white pulp of the mouse spleen: An in vivo and in vitro study

P. Eikelenboom, Drs. P. Eikelenboom, 1978, Cell and Tissue Research.

Distribution of f 3 / A 4 Protein and Amyloid Precursor Protein in Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch Type and Alzheimer ' s Disease

W. Kamphorst, P. Eikelenboom, A. Rozemuller, 2007 .

Distribution of beta/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease.

W. Kamphorst, W. V. Van Nostrand, P. Eikelenboom, 1993, The American journal of pathology.

Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease.

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2001, Experimental gerontology.

Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q

J. Langeveld, R. Veerhuis, R. Boshuizen, 2005, Neurobiology of Disease.

P3-216 Neuronal immunoreactivity for COX-2 and phosphorylation of PRB precede P38 MAPK activation and neurofibrillary changes in AD temporal cortex

T. Arendt, R. Veerhuis, P. Eikelenboom, 2004, Neurobiology of Aging.

Inflammatory mechanisms in Alzheimer's disease.

P. Eikelenboom, D. Allsop, W. V. van Gool, 1994, Trends in pharmacological sciences.

Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis.

P. Eikelenboom, J. D. de Jonghe, W. V. van Gool, 2010, JAMA.

Delirium detection using relative delta power based on 1‐minute single‐channel EEG: a multicentre study

Frans S. Leijten, Carsten Leue, Christian H. Röder, 2019, British journal of anaesthesia.

NSAIDS inhibit the IL-1β-induced IL-6 release from human post-mortem astrocytes: the involvement of prostaglandin E2

C. Finch, R. Veerhuis, P. Eikelenboom, 1997, Brain Research.

The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease: therapeutic implications

P. Eikelenboom, J. M. Rozemuller-Kwakkel, A. GoolvanW., 2005 .

Sodium valproate in the treatment of aggressive behavior in patients with dementia—a randomized placebo controlled clinical trial

P. Jansen, P. Eikelenboom, S. Duursma, 2002, International journal of geriatric psychiatry.

Anti-inflammatory therapy in Alzheimer’s disease: is hope still alive?

P. Aisen, P. Eikelenboom, W. A. Gool, 2003, Journal of Neurology.

Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2006, International Journal of Developmental Neuroscience.

Dementia and mortality in persons with Down's syndrome.

P. Eikelenboom, P. V. Gool, H. Evenhuis, 2006, Journal of intellectual disability research : JIDR.

Routine use of the confusion assessment method for the intensive care unit: a multicenter study.

F. de Leeuw, M. Kuiper, S. D. de Rooij, 2011, American journal of respiratory and critical care medicine.

Neuroinflammation in Alzheimer's disease and prion disease

R. Veerhuis, P. Eikelenboom, W. V. van Gool, 2002, Glia.

Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations

H. Fraser, P. Eikelenboom, D. Ritchie, 1997, Brain Research.

Dendritic cells in the rat spleen follicles

P. Eikelenboom, Drs. P. Eikelenboom, 1978, Cell and Tissue Research.

In-vivo effects of lipopolysaccharide on lymphoid and non-lymphoid cells in the mouse spleen

P. Eikelenboom, N. Rooijen, P. Groeneveld, 2004, Cell and Tissue Research.

Development of T and B cell areas in peripheral lymphoid organs of the rat

P. Eikelenboom, J. Streefkerk, Muriel G. E. Levenbach, 1979, The Anatomical record.

Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex

T. Arendt, R. Veerhuis, P. Eikelenboom, 2004, Neurobiology of Disease.

The importance of inflammatory mechanisms for the development of Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, 1999, Experimental Gerontology.

Astrocytic Aβ1‐42 uptake is determined by Aβ‐aggregation state and the presence of amyloid‐associated proteins

R. Veerhuis, P. Eikelenboom, J. Beliën, 2010, Glia.

Whether, when and how chronic inflammation increases the risk of developing late-onset Alzheimer's disease

R. Veerhuis, P. Eikelenboom, E. van Exel, 2012, Alzheimer's Research & Therapy.

The early involvement of the innate immunity in the pathogenesis of late-onset Alzheimer's disease: neuropathological, epidemiological and genetic evidence.

R. Veerhuis, P. Eikelenboom, W. V. van Gool, 2011, Current Alzheimer research.

Systemic infection and delirium: when cytokines and acetylcholine collide

P. Eikelenboom, D. Beek, Willem A van Gool, 2010, The Lancet.

Microglia activation in sepsis: a case-control study

Afina W Lemstra, P. Eikelenboom, A. Lemstra, 2007, Journal of Neuroinflammation.

Preoperative Cerebrospinal Fluid Cortisol and the Risk of Postoperative Delirium: A Prospective Study of Older Hip Fracture Patients

A. MacLullich, P. Eikelenboom, J. D. de Jonghe, 2021, Dementia and Geriatric Cognitive Disorders.

The trajectory of C‐reactive protein serum levels in older hip fracture patients with postoperative delirium

P. Eikelenboom, J. D. de Jonghe, D. Adamis, 2019, International journal of geriatric psychiatry.

The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus.

W. Scheper, P. Eikelenboom, J. Hoozemans, 2009, The American journal of pathology.

Activation of the unfolded protein response in Parkinson's disease.

W. Scheper, P. Eikelenboom, R. Vos, 2007, Biochemical and biophysical research communications.

The unfolded protein response is activated in Alzheimer’s disease

F. Baas, W. Scheper, R. Veerhuis, 2005, Acta Neuropathologica.

Consistent patterns in the inconsistent associations of Insulin-like growth factor 1 (IGF-1), C-Reactive Protein (C-RP) and Interleukin 6 (IL-6) levels with delirium in surgical populations. A systematic review and meta-analysis.

P. Eikelenboom, D. Adamis, W. V. van Gool, 2021, Archives of gerontology and geriatrics.

Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients

A. MacLullich, P. Eikelenboom, J. D. de Jonghe, 2013, Journal of Neuroinflammation.

The neuropsychological sequelae of delirium in elderly patients with hip fracture three months after hospital discharge

P. Eikelenboom, J. D. de Jonghe, R. Jansen, 2013, International Psychogeriatrics.

Long-Term Cognitive Outcome of Delirium in Elderly Hip Surgery Patients

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2008, Dementia and Geriatric Cognitive Disorders.

Pre‐operative inflammatory markers and the risk of postoperative delirium in elderly patients

P. Eikelenboom, A. Lemstra, W. V. van Gool, 2008, International journal of geriatric psychiatry.

Risk Factors and Prediction of Postoperative Delirium in Elderly Hip‐Surgery Patients: Implementation and Validation of a Medical Risk Factor Model

P. Eikelenboom, J. D. de Jonghe, W. V. van Gool, 2006, Journal of the American Geriatrics Society.

Immunological mechanisms and the spectrum of psychiatric syndromes in Alzheimer's disease.

C. Jonker, C. Jonker, P. Eikelenboom, 2002, Journal of psychiatric research.

Cerebrospinal Fluid β‐Amyloid and Tau Are Not Associated with Risk of Delirium: A Prospective Cohort Study in Older Adults with Hip Fracture

P. Eikelenboom, J. D. de Jonghe, N. Verwey, 2011, Journal of the American Geriatrics Society.

Anesthesia and Postoperative Delirium in Older Adults Undergoing Hip Surgery

B. Schmand, P. Eikelenboom, J. D. de Jonghe, 2011, Journal of the American Geriatrics Society.

Open peer commentary Inflammation and Alzheimer's disease

C. Finch, H. Hampel, G. Cole, 2000 .

Immunoglobulins and complement factors in senile plaques

P. Eikelenboom, F. Stam, 1982, Acta Neuropathologica.

Survival in Elderly Persons with Down Syndrome

A. Janssens, C. V. van Duijn, B. Oostra, 2008, Journal of the American Geriatrics Society.

The impact of apolipoprotein E on dementia in persons with Down's syndrome

C. M. van Duijn, C. Duijn, A. Arias-Vasquez, 2008, Neurobiology of Aging.

Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.

R. Kalaria, P. Eikelenboom, A. Rozemuller, 1992, Neuroreport.

Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin.

P. Eikelenboom, F. Stam, J. Abbink, 1991, Acta neuropathologica.

Lack of association between depression and loss of neurons in the locus coeruleus in Alzheimer disease.

W. Kamphorst, D. Swaab, P. Eikelenboom, 1999, Archives of general psychiatry.

Costimulatory effects of interferon-gamma and interleukin-1beta or tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes.

R. Veerhuis, P. Eikelenboom, I. Blasko, 2000, Neurobiology of disease.

Cytokines Associated with Amyloid Plaques in Alzheimer's Disease Brain Stimulate Human Glial and Neuronal Cell Cultures to Secrete Early Complement Proteins, But Not C1-Inhibitor

R. Veerhuis, C. Hack, P. Eikelenboom, 1999, Experimental Neurology.

Complement C1-inhibitor expression in Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 1998, Acta Neuropathologica.

Amyloid β Protein Primes Cultured Rat Microglial Cells for an Enhanced Phorbol 12‐Myristate 13‐Acetate‐Induced Respiratory Burst Activity

R. Veerhuis, P. Eikelenboom, F. L. van Muiswinkel, 1996, Journal of neurochemistry.

Serum inflammatory proteins and cognitive decline in older persons

J. Smit, C. Jonker, C. Jonker, 2005, Neurology.

The Involvement of Aβ in the Neuroinflammatory Response

W. Scheper, R. Veerhuis, P. Eikelenboom, 2007 .

Apolipoproteins E and J interfere with amyloid‐beta uptake by primary human astrocytes and microglia in vitro

M. Blankenstein, R. Veerhuis, P. Eikelenboom, 2014, Glia.

Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease

M. Mirmiran, D. F. Swaab, M. Mirmiran, 1990, Biological Psychiatry.

Immunological Aspects of Alzheimer’s Disease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2012, BioDrugs.

Neuroinflammatory perspectives on the two faces of Alzheimer’s disease

P. Eikelenboom, W. A. Gool, W. V. van Gool, 2004, Journal of Neural Transmission.

Amyloid β plaque-associated proteins C1q and SAP enhance the Aβ1–42 peptide-induced cytokine secretion by adult human microglia in vitro

M. V. van Breemen, R. Veerhuis, P. Eikelenboom, 2003, Acta Neuropathologica.

Neuroinflammatio ni nAlzheimer's Diseas ean dPrio nDisease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2002 .

Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2000, Acta Neuropathologica.

Inflammation and Alzheimer's Disease: Relationships between Pathogenic Mechanisms and Clinical Expression

P. Eikelenboom, F. L. Muiswinkel, J. Rozemuller, 1998, Experimental Neurology.

Cytokines, prostaglandins and lipocortin-1 are present in the brains of scrapie-infected mice

H. Fraser, P. Eikelenboom, A. Williams, 1994, Brain Research.

Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

R. Veerhuis, P. Eikelenboom, W. V. van Gool, 2010, Neurodegenerative Diseases.

Complement activation in amyloid plaques in Alzheimer’s dementia

P. Eikelenboom, F. Stam, C. Hack, 1988, Virchows Archiv. B, Cell pathology including molecular pathology.

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

P. Eikelenboom, F. Stam, S. Pals, 1989, Neuroscience Letters.

An immunohistochemical study on cerebral vascular and senile plaque amyloid in Alzheimer’s dementia

P. Eikelenboom, F. Stam, 1984, Virchows Archiv. B, Cell pathology including molecular pathology.

Schizophrenia spectrum disorders in later life: prevalence and distribution of age at onset and sex in a dutch catchment area.

A. Beekman, J. Smit, M. Stek, 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Theory of Mind differences in older patients with early‐onset and late‐onset paranoid schizophrenia

A. Beekman, J. Smit, M. Stek, 2013, International journal of geriatric psychiatry.

Cognitive impairment in late life schizophrenia and bipolar I disorder

A. Beekman, M. Stek, P. Eikelenboom, 2013, International journal of geriatric psychiatry.

The two faces of Alzheimer's disease

P. Eikelenboom, W. A. Gool, W. V. van Gool, 2000, Journal of Neurology.

Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress

F. Baas, C. Hoogenraad, W. Scheper, 2007, Neuropathology and applied neurobiology.

Social functioning among older community-dwelling patients with schizophrenia: a review.

A. Beekman, T. Patterson, M. Stek, 2010, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Minocycline does not affect amyloid β phagocytosis by human microglial cells

R. Veerhuis, A. Familian, P. Eikelenboom, 2007, Neuroscience Letters.

Cyclin D1 and Cyclin E Are Co‐Localized with Cyclo‐Oxygenase 2 (COX‐2) in Pyramidal Neurons in Alzheimer Disease Temporal Cortex

T. Arendt, R. Veerhuis, P. Eikelenboom, 2002, Journal of neuropathology and experimental neurology.

Characteristics of Dyshoric Capillary Cerebral Amyloid Angiopathy

P. Eikelenboom, E. Richard, H. D. de Vries, 2010, Journal of neuropathology and experimental neurology.

The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E2 secretion by cultured human adult microglia: Implications for Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2002, Brain Research.

The amino-terminus of the amyloid-β protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages

P. Eikelenboom, F. L. Muiswinkel, J. Verhoef, 1999, Journal of Neuroimmunology.

Acute phase proteins but not activated microglial cells are present in parenchymal β A4 deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type

R. Roos, P. Eikelenboom, J. Rozemuller, 1992, Neuroscience Letters.

Inflammation and remission in older patients with depression treated with electroconvulsive therapy; findings from the MODECT study✰.

P. Sienaert, M. Stek, R. Veerhuis, 2019, Journal of affective disorders.

MRI and cerebrospinal fluid biomarkers for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: a diagnostic accuracy study

B. Schmand, P. Eikelenboom, E. Richard, 2013, BMJ Open.

The unfolded protein response affects neuronal cell cycle protein expression: Implications for Alzheimer's disease pathogenesis

F. Baas, W. Scheper, T. Arendt, 2006, Experimental Gerontology.

Is there a single differentiation pathway for all antibody-forming cells in the spleen?

P. Eikelenboom, N. Van Rooijen, E. Claassen, 1986, Immunology today.

The Cholinergic Deficiency Syndrome and Its Therapeutic Implications

P. Eikelenboom, A. Lemstra, W. V. van Gool, 2002, Gerontology.

OR PART OF THE FOLLOWING SOURCE ) : Type article Title Steroid responsive encephalopathy in cerebral amyloid angiopathy : a case report and review of evidence for immunosuppressive treatment

D. Troost, P. Nederkoorn, P. Eikelenboom, 2010 .

The care needs of elderly patients with schizophrenia spectrum disorders.

A. Beekman, J. Smit, R. Dröes, 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Subjective quality of life and its determinants in a catchment area based population of elderly schizophrenia patients

A. Beekman, J. Smit, M. Stek, 2013, Schizophrenia Research.

The role of complement and activated microglia in the pathogenesis of Alzheimer's disease

R. Veerhuis, P. Eikelenboom, 1996, Neurobiology of Aging.

Symptoms of Apathy Are Associated with Progression from Mild Cognitive Impairment to Alzheimer’s Disease in Non-Depressed Subjects

B. Schmand, P. Eikelenboom, E. Richard, 2012, Dementia and Geriatric Cognitive Disorders.

Exploring resting state connectivity in patients with psychotic depression

F. Barkhof, Y. D. van der Werf, P. Sienaert, 2019, PloS one.

Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease

P. Eikelenboom, F. Stam, J. Rozemuller, 1990, Neuroscience Letters.

The Role of Insulin-Like Growth Factor 1 in Delirium: A Systematic Review and Meta-Analysis

P. Eikelenboom, D. Adamis, 2023, Dementia and Geriatric Cognitive Disorders.

Delirium, insulin-like growth factor I, growth hormone in older inpatients

D. Meagher, P. Eikelenboom, D. Adamis, 2020, World journal of psychiatry.

Hypochondriacal delusion in an elderly woman recovers quickly with electroconvulsive therapy

M. Stek, P. Eikelenboom, D. Rhebergen, 2012, Clinics and practice.

Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro.

M. V. van Breemen, R. Veerhuis, P. Eikelenboom, 2003, Acta neuropathologica.

The Pitfall of Behavioral Variant Frontotemporal Dementia Mimics Despite Multidisciplinary Application of the FTDC Criteria.

W. M. van der Flier, P. Scheltens, Y. Pijnenburg, 2017, Journal of Alzheimer's disease : JAD.

Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease

W. Scheper, T. Arendt, R. Veerhuis, 2005, Journal of Neuroinflammation.

Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology.

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2008, Current pharmaceutical design.

P. Scheltens, L. Wahlund, S. Schoonenboom, 2002, Journal of Neural Transmission.

Preoperative protein profiles in cerebrospinal fluid in elderly hip fracture patients at risk for delirium: A proteomics and validation study

B. V. van Munster, S. D. de Rooij, P. Eikelenboom, 2015, BBA clinical.

[The development of psychotic symptoms in later life: late-onset schizophrenia or frontotemporal dementia? A case study].

Y. Pijnenburg, P. Eikelenboom, W. van Tilburg, 2006, Tijdschrift voor psychiatrie.

Are Apathy and Depressive Symptoms Related to Vascular White Matter Hyperintensities in Severe Late Life Depression?

F. Barkhof, P. Sienaert, M. Stek, 2020, Journal of geriatric psychiatry and neurology.

Dyshoric capillary cerebral amyloid angiopathy mimicking Creutzfeldt–Jakob disease

P. Eikelenboom, E. Richard, W. A. Gool, 2010, Journal of the Neurological Sciences.

Affective functioning after delirium in elderly hip fracture patients

D. Meagher, P. Eikelenboom, J. D. de Jonghe, 2012, International Psychogeriatrics.

Neuroinflammation in Plaque and Vascular β-Amyloid Disorders: Clinical and Therapeutic Implications

R. Veerhuis, A. Familian, P. Eikelenboom, 2008, Neurodegenerative Diseases.

A4 Protein in Alzheimer's Disease: Primary and Secondary Cellular Events in Extracellular Amyloid Deposition

K. Beyreuther, P. Eikelenboom, C. Masters, 1989, Journal of neuropathology and experimental neurology.

Activated microglia and cerebral amyloid deposits in Alzheimer's disease.

P. Eikelenboom, P. Van Der Valk, J. Rozemuller, 1992, Research in immunology.

Innate Immunity and the Etiology of Late-Onset Alzheimer’s Disease

R. Veerhuis, P. Eikelenboom, W. V. van Gool, 2012, Neurodegenerative Diseases.

Early- and Late-Onset Depression in Late Life: A Prospective Study on Clinical and Structural Brain Characteristics and Response to Electroconvulsive Therapy.

F. Barkhof, P. Sienaert, K. Vansteelandt, 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Parental history of Alzheimer disease associated with lower plasma apolipoprotein E levels

W. M. van der Flier, P. Eikelenboom, R. Westendorp, 2009, Neurology.

Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease.

P. Scheltens, J. Smit, R. Westendorp, 2009, Archives of general psychiatry.

Value of diagnostic tests to predict conversion to Alzheimer's disease in young and old patients with amnestic mild cognitive impairment.

B. Schmand, P. Eikelenboom, W. V. van Gool, 2012, Journal of Alzheimer's disease : JAD.

Heparan Sulfate Proteoglycan Is Associated with Amyloid Plaques and Neuroanatomically Targeted PrP Pathology throughout the Incubation Period of Scrapie-Infected Mice

P. Eikelenboom, M. Wilson, P. McBride, 1998, Experimental Neurology.

The Alzheimer myth and biomarker research in dementia.

R. Westendorp, B. Schmand, P. Eikelenboom, 2012, Journal of Alzheimer's disease : JAD.

Increased activity of surviving locus ceruleus neurons in Alzheimer's disease

W. Kamphorst, D. Swaab, P. Eikelenboom, 1999, Annals of neurology.

Decreased DNA repair capacity in familial, but not in sporadic Alzheimer's disease

A. Hofman, E. Mullaart, C. Duijn, 1991, Neurobiology of Aging.

Distribution pattern and functional state of complement proteins and alpha 1-antichymotrypsin in cerebral beta/A4 deposits in Alzheimer's disease.

W. Kamphorst, P. Eikelenboom, C. Hack, 1992, Research in immunology.

Mortality and Its Determinants in Late-Life Schizophrenia: A 5-Year Prospective Study in a Dutch Catchment Area.

A. Beekman, J. Smit, M. Stek, 2016, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Microglia kill amyloid-&bgr;1-42 damaged neurons by a CD14-dependent process

R. Veerhuis, P. Eikelenboom, Alun Williams, 2004, NeuroReport.

Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly

W. Kamphorst, P. Eikelenboom, S. Zhan, 2004, Acta Neuropathologica.

Microglia, amyloid and dementia in Alzheimer disease A correlative study

C. Duyckaerts, J. Hauw, P. Eikelenboom, 2000, Neurobiology of Aging.

Source (or Part of the following Source): Type Article Title Neuroinflammation in Alzheimer's Disease Wanes with Age Author(s) Neuroinflammation in Alzheimer's Disease Wanes with Age

P. Eikelenboom, W. V. van Gool, J. Hoozemans, 2022 .

Contribution of white matter hyperintensities, medial temporal lobe atrophy and cortical atrophy on outcome, seven to twelve years after ECT in severely depressed geriatric patients.

F. Barkhof, M. Stek, P. Eikelenboom, 2015, Journal of affective disorders.

White matter hyperintensities, medial temporal lobe atrophy, cortical atrophy, and response to electroconvulsive therapy in severely depressed elderly patients.

A. Beekman, P. Scheltens, F. Barkhof, 2011, The Journal of clinical psychiatry.

Does IFNγ play a role in neurodegeneration?

R. Veerhuis, P. Eikelenboom, G. Ransmayr, 2001, Journal of Neuroimmunology.

S100 calcium-binding protein B in older patients with depression treated with electroconvulsive therapy

P. Sienaert, M. Stek, R. Veerhuis, 2019, Psychoneuroendocrinology.

α1-Antitrypsin and α1-antichymotrypsin are in the lesions of Alzheimer's disease

R. Kalaria, P. Eikelenboom, A. Rozemuller, 1992 .

Clusterin: An early biomarker for Alzheimer's disease?

P. Scheltens, W. Flier, M. Blankenstein, 2013, Alzheimer's & Dementia.

Prevalence and correlates of depressive symptoms in a catchment-area based cohort of older community-living schizophrenia patients

A. Beekman, M. Stek, P. Eikelenboom, 2014, Schizophrenia Research.

White matter hyperintensities and cognitive impairment during electroconvulsive therapy in severely depressed elderly patients.

A. Beekman, P. Scheltens, F. Barkhof, 2014, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Minocycline does not affect amyloid beta phagocytosis by human microglial cells.

R. Veerhuis, A. Familian, P. Eikelenboom, 2007, Neuroscience letters.

Sleep and circadian rhythm changes in Alzheimer's disease

M. Mirmiran, D. Swaab, P. Eikelenboom, 1991 .

Predicting Delirium Duration in Elderly Hip-Surgery Patients: Does Early Symptom Profile Matter?

D. Meagher, P. Eikelenboom, J. D. de Jonghe, 2013, Current gerontology and geriatrics research.

Mechanism of follicular trapping: similarities and differences in trapping of antibody-complexed antigens and carbon particles in the follicles of the spleen.

P. Eikelenboom, N. Van Rooijen, P. Groeneveld, 1983, Journal of the Reticuloendothelial Society.

Always around, never the same: pathways of amyloid beta induced neurodegeneration throughout the pathogenic cascade of Alzheimer's disease.

F. Baas, W. Scheper, P. Eikelenboom, 2006, Current medicinal chemistry.

Activated microglial cells and complement factors are unrelated to cortical Lewy bodies

P. Eikelenboom, A. Rozemuller, R. D. de Vos, 2000, Acta Neuropathologica.

Inflammation and Cognitive Functioning in Depressed Older Adults Treated With Electroconvulsive Therapy: A Prospective Cohort Study.

P. Sienaert, M. Stek, R. Veerhuis, 2021, The Journal of clinical psychiatry.

The pathological cascade of Alzheimer's disease: the role of inflammation and its therapeutic implications.

R. Veerhuis, P. Eikelenboom, A. Rozemuller, 2002, Drugs of today.

Neuroinflammation in Early Stages of Alzheimer’s Disease and Parkinson’s Disease

R. Veerhuis, P. Eikelenboom, W. A. Gool, 2008 .

Immunological fac tors in Alzheimer's diseas

P. Eikelenboom, C. Abraham, 1992 .

Does IFNgamma play a role in neurodegeneration?

R. Veerhuis, P. Eikelenboom, G. Ransmayr, 2001, Journal of Neuroimmunology.

P0334 - Long-term cognitive outcome of delirium in elderly hip-surgery patients

P. Eikelenboom, J. D. de Jonghe, M. Kat, 2008, European Psychiatry.

Sodium valproate in aggressive behaviour in dementia: a twelve‐week open label follow‐up study

P. Jansen, H. Duivenvoorden, P. Eikelenboom, 2004, International journal of geriatric psychiatry.

Non-steroidal anti-inflammatory drugs and cyclooxygenase in Alzheimer's disease.

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2003, Current drug targets.

Symptomatic remission and associated factors in a catchment area based population of older patients with schizophrenia

A. Beekman, J. Smit, M. Stek, 2011, Schizophrenia Research.

The pattern of inflammatory markers during electroconvulsive therapy in older depressed patients

P. Sienaert, M. Stek, R. Veerhuis, 2021, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease

W. Scheper, T. Arendt, R. Veerhuis, 2005, Journal of Neuroinflammation.

Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease

W. Scheper, T. Arendt, R. Veerhuis, 2005 .

Cyclooxygenase expression in microglia and neurons in Alzheimer's disease brain

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2000, Neurobiology of Aging.

Brain alterations in depression

D. Swaab, P. Eikelenboom, W. Hoogendijk, 2000, Acta Neuropsychiatrica.

Journal of Neuroinflammation Microglia Activation in Sepsis: a Case-control Study

P. Eikelenboom, A. Lemstra, W. V. van Gool, 2022 .

Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease.

P. Scheltens, J. Smit, R. Westendorp, 2009, Archives of general psychiatry.

Value of diagnostic tests to predict conversion to Alzheimer's disease in young and old patients with amnestic mild cognitive impairment.

B. Schmand, P. Eikelenboom, W. V. van Gool, 2012, Journal of Alzheimer's disease : JAD.

Routine use of the confusion assessment method for the intensive care unit: a multicenter study.

F. de Leeuw, M. Kuiper, S. D. de Rooij, 2011, American journal of respiratory and critical care medicine.

Early- and Late-Onset Depression in Late Life: A Prospective Study on Clinical and Structural Brain Characteristics and Response to Electroconvulsive Therapy.

F. Barkhof, P. Sienaert, K. Vansteelandt, 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Social functioning among older community-dwelling patients with schizophrenia: a review.

A. Beekman, T. Patterson, M. Stek, 2010, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

The mediating role of cardiovascular risk factors in the relationship between symptoms of apathy and incident cardiovascular disease in community-dwelling older individuals

J. Jaccard, P. Eikelenboom, E. Richard, 2015, International Psychogeriatrics.

Vascular factors in dementia and apathy

J. Jaccard, P. Eikelenboom, E. Richard, 2016 .

Immunological aspects of alzheimer's disease: therapeutic implications.

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 2001, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.