J. Pachter

发表

C. Plata-salamán, C. Finch, H. Hampel, 2000, Neurobiology of Aging.

Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis

J. Pachter, Debayon Paul, B. Shrestha, 2017, Neurobiology of Disease.

Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE

J. Pachter, Debayon Paul, Shujun Ge, 2021, Journal of neuroinflammation.

Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE

J. Pachter, Debayon Paul, Shujun Ge, 2021, Journal of Neuroinflammation.

Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE

J. Pachter, Debayon Paul, Shujun Ge, 2021, Journal of Neuroinflammation.

Analysis of mouse brain microvascular endothelium using immuno‐laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform‐mass spectrometry proteomics platform

W. Hancock, J. Pachter, Shiaw-lin Wu, 2008, Electrophoresis.

The CCL 2 Synthesis Inhibitor Bindarit Targets Cells of the Neurovascular Unit , and Suppresses Experimental Autoimmune Encephalomyelitis

J. Pachter, Debayon Paul, A. Guglielmotti, 2019 .

Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro

J. Pachter, D. Biegel, D. Spence, 1995, Brain Research.

The Blood–Brain Barrier: Geriatric Relevance of a Critical Brain–Body Interface

L. McCullough, L. Wolfson, G. Kuchel, 2010, Journal of the American Geriatrics Society.

Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs

J. Pachter, T. Yen, D. Cleveland, 1987, Cell.

Brain regional angiogenic potential at the neurovascular unit during normal aging

J. Pachter, T. Demarest, J. Madri, 2012, Neurobiology of Aging.

Isolation and culture of microvascular endothelial cells from murine spinal cord

J. Pachter, Shujun Ge, 2006, Journal of Neuroimmunology.

Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection.

J. Pachter, Katie Kinnecom, 2005, Brain research. Brain research protocols.

Caveolin-1 Knockdown by Small Interfering RNA Suppresses Responses to the Chemokine Monocyte Chemoattractant Protein-1 by Human Astrocytes*

J. Pachter, Shujun Ge, 2004, Journal of Biological Chemistry.

Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics.

W. Hancock, J. Pachter, Shiaw-lin Wu, 2011, Methods in molecular biology.

P-glycoprotein regulates trafficking of CD8+ T cells to the brain parenchyma

D. Geerts, J. Pachter, Debayon Paul, 2014, Acta Neuropathologica.

The Chemokine Receptor Ccr2 Mediates the Binding and Internalization of Monocyte Chemoattractant Protein-1 along Brain Microvessels

J. Pachter, K. Dzenko, W. Kuziel, 2022 .

The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration

J. Pachter, R. Zigmond, J. Niemi, 2022, Journal of neuroinflammation.

Endothelial Cell Heterogeneity of Blood–Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR

J. Pachter, T. Demarest, Nivetha Murugesan, 2012 .

A batchwise purification procedure of neurofilament proteins.

J. Pachter, R. Liem, S. B. Hutchison, 1983, Analytical biochemistry.

Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells.

J. Pachter, Li Song, 2004, Microvascular research.

Expression of binding sites for beta chemokines on human astrocytes.

J. Pachter, L. Pulliam, D. Kerkovich, 1999, Glia.

Neurocytopathic effects of beta-amyloid-stimulated monocytes: a potential mechanism for central nervous system damage in Alzheimer disease.

J. Pachter, D. Biegel, J. London, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Transcellular transport of CCL2 across brain microvascular endothelial cells

J. Pachter, W. Kuziel, Shujun Ge, 2008, Journal of neurochemistry.

CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2.

J. Pachter, K. Dzenko, W. Kuziel, 2005, Microvascular research.

Engagement of the Scavenger Receptor Is Not Responsible for β-Amyloid Stimulation of Monocytes to a Neurocytopathic State

J. Pachter, K. Dzenko, A. Antić, 2000, Experimental Neurology.

Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

J. Pachter, Debayon Paul, Xi Jiang, 2019, Fluids and Barriers of the CNS.

Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease

R. Mains, M. Niciu, J. Pachter, 2007, Neurobiology of Disease.

Inflammatory mechanisms in Alzheimer disease: the role of beta-amyloid/glial interactions

J. Pachter, 1997, Molecular Psychiatry.

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation

J. Pachter, Debayon Paul, Shujun Ge, 2014, Journal of Neuroinflammation.

Systemic TLR2 tolerance enhances central nervous system remyelination

J. Pachter, Debayon Paul, K. Khanna, 2019, Journal of Neuroinflammation.

beta-Internexin, a ubiquitous intermediate filament-associated protein

S. Chin, J. Pachter, R. Liem, 1985, The Journal of cell biology.

alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues

J. Pachter, R. Liem, Ronald, 1985, The Journal of cell biology.

Association of mRNA with the cytoskeletal framework: its role in the regulation of gene expression.

J. Pachter, 1992, Critical reviews in eukaryotic gene expression.

Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease

J. Pachter, A. Andjelkovic, 1998, Journal of neuroscience research.

Culture of murine brain microvascular endothelial cells that maintain expression and cytoskeletal association of tight junction-associated proteins

J. Pachter, Li Song, 2003, In Vitro Cellular & Developmental Biology - Animal.

Alterations in Tight Junction Protein and IgG Permeability Accompany Leukocyte Extravasation Across the Choroid Plexus During Neuroinflammation

J. Pachter, Debayon Paul, B. Shrestha, 2014, Journal of neuropathology and experimental neurology.

Functional expression of CCR2 by human fetal astrocytes

J. Pachter, K. Dzenko, H. Cong, 2002, Journal of neuroscience research.

Beta-actin mRNA-binding proteins associated with the cytoskeletal framework.

J. Pachter, T. Yang, K. Sharpless, 1993, European journal of biochemistry.

Actin Depolymerization Is Developmentally Regulated in Rat Type II Cells Exposed to Terbutaline

V. Bhandari, J. Pachter, Hsienwie Lu, 1997, Pediatric Research.

Astrocyte- and Endothelial-Targeted CCL2 Conditional Knockout Mice: Critical Tools for Studying the Pathogenesis of Neuroinflammation

J. Pachter, Shujun Ge, Nivetha Murugesan, 2009, Journal of Molecular Neuroscience.

Growth of brain microvessel endothelial cells on collagen gels: Applications to the study of blood-brain barrier physiology and CNS inflammation

J. Pachter, D. Biegel, 1994, In Vitro Cellular & Developmental Biology - Animal.

The Blood‐Brain Barrier and Its Role in Immune Privilege in the Central Nervous System

Helga E de Vries, J. Pachter, H. D. de Vries, 2003, Journal of neuropathology and experimental neurology.

The Neuronal Cytoskeleton

M. Shelanski, J. Pachter, R. Liem, 1984 .

Characterization of Binding Sites for Chemokines MCP‐1 and MIP‐1α on Human Brain Microvessels

J. Pachter, A. Andjelkovic, 2000, Journal of neurochemistry.

A rapid and sensitive radioimmunoassay for the detection of human cytomegalovirus binding and infection of human fibroblasts.

J. Pachter, J. Shanley, D. Biegel, 1996, Journal of virological methods.

Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells.

J. Pachter, Shujun Ge, Li Song, 2007, Blood.

Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles

J. Pachter, Debayon Paul, D. Agalliu, 2016, Journal of Neuroinflammation.

Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia

N. Williams, K. Murphy, J. Hou, 2017, Molecular Psychiatry.

Endothelial cell heterogeneity of blood‐brain barrier gene expression along the cerebral microvasculature

J. Pachter, Nivetha Murugesan, Jennifer Macdonald, 2009, Journal of neuroscience research.

Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

A. Andrews, J. Pachter, Debayon Paul, 2018, Fluids and Barriers of the CNS.

Open peer commentary Inflammation and Alzheimer's disease

C. Finch, H. Hampel, G. Cole, 2000 .

Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood–brain barrier gene expression in situ

J. Pachter, Nivetha Murugesan, Jennifer Macdonald, 2008, Journal of Neuroscience Methods.

“In situ” translation: Use of the cytoskeletal framework to direct cell-free protein synthesis

J. Pachter, D. Biegel, 2007, In Vitro Cellular & Developmental Biology - Animal.

mRNA association with the cytoskeletal framework likely represents a physiological binding event

J. Pachter, D. Biegel, 1992, Journal of cellular biochemistry.

Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis

Nicholas A. Kouris, J. Chu, J. Pachter, 2014, Stem cell reports.

Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus

J. Pachter, Debayon Paul, B. Shrestha, 2012, Fluids and Barriers of the CNS.

Expression of binding sites for β chemokines on human astrocytes

J. Pachter, L. Pulliam, D. Kerkovich, 1999 .

Qualitative and quantitative analysis of monocyte transendothelial migration by confocal microscopy and three-dimensional image reconstruction

M. Zochowski, J. Pachter, F. Morgan, 2007, In Vitro Cellular & Developmental Biology - Animal.

Laser-Capture Microdissection and RNA Extraction from Perfusion-Fixed Cartilage and Bone Tissue from Mice Implanted with Human iPSC-Derived MSCs in a Calvarial Defect Model.

Xi Jiang, D. Rowe, J. Pachter, 2018, Methods in molecular biology.

Mitofusin‐2 regulates leukocyte adhesion and β2 integrin activation

A. Groisman, J. Pachter, Penghua Wang, 2021, Journal of leukocyte biology.

Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides

J. Pachter, T. Yen, D. Cleveland, 1988, Molecular and cellular biology.

Biodegradable nanofiber-based piezoelectric transducer

Xiaonan Xin, Asiyeh Golabchi, David Rowe, 2019, Proceedings of the National Academy of Sciences.

The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve.

J. Pachter, R. Liem, Ronald K.H. Liem, 1984, Developmental biology.

Monocyte:astrocyte interactions regulate MCP‐1 expression in both cell types

J. Pachter, D. Kerkovich, A. Andjelkovic, 2000, Journal of leukocyte biology.

Where is the blood–brain barrier … really?

J. Pachter, Shujun Ge, Li Song, 2005, Journal of neuroscience research.

Macrophages/microglial cells in human central nervous system during development: an immunohistochemical study

N. Zečević, J. Pachter, A. Andjelkovic, 1998, Brain Research.

Suppression of Aβ-induced monocyte neurotoxicity by antiinflammatory compounds

J. Pachter, K. Dzenko, R. Weltzien, 1997, Journal of Neuroimmunology.

Visualization of beta‐amyloid peptide (Aβ) phagocytosis by human mononuclear phagocytes: dependency on Aβ aggregate size

J. Pachter, R. Weltzien, Robert B. Weltzien, 2000, Journal of neuroscience research.

Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

A. Andrews, J. Pachter, Debayon Paul, 2018, Fluids and Barriers of the CNS.

Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation

J. Pachter, B. Shrestha, Shujun Ge, 2014, Fluids and Barriers of the CNS.

Novel 3D analysis of Claudin-5 reveals significant endothelial heterogeneity among CNS microvessels.

J. Pachter, Debayon Paul, Shujun Ge, 2013, Microvascular research.

Brain tryptophan in isolated aggressive mice.

L. Valzelli, J. Pachter, B. Miller, 1979, Neuropsychobiology.

Bindarit, inhibitor of CCL2 synthesis, protects neurons against amyloid-β-induced toxicity.

M. Ciotti, J. Pachter, A. Guglielmotti, 2013, Journal of Alzheimer's disease : JAD.

The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

J. Pachter, Debayon Paul, A. Guglielmotti, 2012, Journal of Neuroinflammation.

Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

J. Pachter, Debayon Paul, Xi Jiang, 2019, Fluids and Barriers of the CNS.

Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan® Low Density Array

J. Pachter, T. Demarest, B. Shrestha, 2012, Journal of Neuroscience Methods.

Chemokines and Chemokine Receptors along the Brain Microvasculature

J. Pachter, A. Andjelkovic, 2002 .

Visualization of Chemokine Binding Sites on Human Brain Microvessels

Dennis D. Spencer, D. Spencer, J. Pachter, 1999, The Journal of cell biology.

Systemic TLR2 tolerance enhances central nervous system remyelination

J. Pachter, Debayon Paul, K. Khanna, 2019, Journal of Neuroinflammation.

Associated Proteins as Possible Cross‐Linkers in the Neuronal Cytoskeleton a

J. Pachter, R. Liem, E. Napolitano, 1985, Annals of the New York Academy of Sciences.

/ 3-1 nternexin , a Protein Ubiquitous Intermediate Filament-associated

J. Pachter, R. Liem, E. Napolitano, 2002 .

Technical caveats in identifying the source of endothelial cells in cultures derived from brain microvessels

J. Pachter, Li Song, 2005, Laboratory Investigation.

Intracellular distribution of mammalian stress proteins. Effects of cytoskeletal-specific agents.

J. Pachter, R. Liem, E. Napolitano, 1987, Journal of Biological Chemistry.

Suppression of A beta-induced monocyte neurotoxicity by antiinflammatory compounds.

J. Pachter, K. Dzenko, R. Weltzien, 1997, Journal of neuroimmunology.

Brain regional angiogenic potential at the neurovascular unit during normal aging

J. Pachter, T. Demarest, J. Madri, 2012, Neurobiology of Aging.

Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis

J. Pachter, Debayon Paul, B. Shrestha, 2017, Neurobiology of Disease.

Proteomic interrogation of the meninges reveals the molecular identities of structural components and regional distinctions along the CNS axis

J. Pachter, Jeremy L. Balsbaugh, Shujun Ge, 2023, Fluids and Barriers of the CNS.

beta-Internexin, a ubiquitous intermediate filament-associated protein

S. Chin, J. Pachter, R. Liem, 1985, The Journal of cell biology.

The Chemokine Receptor CCR2 Mediates the Binding and Internalization of Monocyte Chemoattractant Protein-1 along Brain Microvessels

J. Pachter, K. Dzenko, W. Kuziel, 2001, The Journal of Neuroscience.

Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis

J. Pachter, S. Vanaja, A. Shimoyama, 2023, Nature Cell Biology.