A. Christiano

发表

Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC‐Derived Endothelial Cells

S. Sia, H. Abaci, Zongyou Guo, 2016, Advanced healthcare materials.

Next generation human skin constructs as advanced tools for drug development

H. Abaci, Zongyou Guo, A. Christiano, 2017, Experimental biology and medicine.

Compound heterozygous mutations in the hairless gene in atrichia with papular lesions.

A. Christiano, A. Paller, G. Varigos, 2003, The Journal of investigative dermatology.

Mutations in the hairless gene underlie APL in three families of Pakistani origin.

A. Christiano, L. Kraemer, M. Wajid, 2008, Journal of dermatological science.

Atrichia with Papular Lesions Resulting from Novel Compound Heterozygous Mutations in the Human Hairless Gene

A. Christiano, A. Theos, A. Martinez-Mir, 2007, Pediatric dermatology.

Nonsense mutations in the hairless gene underlie APL in five families of Pakistani origin.

A. Christiano, Hyunmi Kim, L. Kraemer, 2007, Journal of dermatological science.

A recurrent splice‐site mutation in the human hairless gene underlies congenital atrichia in Irish families

A. Christiano, A. Irvine, A. Martinez-Mir, 2007, The British journal of dermatology.

Novel compound heterozygous nonsense mutations in the hairless gene causing atrichia with papular lesions.

A. Christiano, A. Martinez-Mir, A. Zlotogorski, 2005, Journal of dermatological science.

Identification of a recurrent mutation in the human hairless gene underlying atrichia with papular lesions

A. Christiano, A. Martinez-Mir, H. Lam, 2005, Clinical and experimental dermatology.

Atrichia with papular lesions resulting from a novel homozygous missense mutation in the hairless gene

A. Christiano, A. Martinez-Mir, M. Paradisi, 2003, Clinical and experimental dermatology.

Congenital atrichia in five Arab Palestinian families resulting from a deletion mutation in the human hairless gene

A. Christiano, W. Ahmad, A. Zlotogorski, 1998, Human Genetics.

Alopecia universalis associated with a mutation in the human hairless gene.

J. Ott, J. Owen, J. McGrath, 1998, Science.

Genomic organization of the human hairless gene (HR) and identification of a mutation underlying congenital atrichia in an Arab Palestinian family.

A. Christiano, W. Ahmad, A. Zlotogorski, 1999, Genomics.

A homozygous nonsense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia.

J. McGrath, A. Christiano, W. Ahmad, 1999, The Journal of investigative dermatology.

Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions.

A. Christiano, A. Zlotogorski, V. Aita, 2001, The Journal of investigative dermatology.

Evidence for pseudodominant inheritance of atrichia with papular lesions.

A. Christiano, Jack Green, R. Sinclair, 2002, The Journal of investigative dermatology.

Atrichia with papular lesions resulting from compound heterozygous mutations in the hairless gene: A lesson for differential diagnosis of alopecia universalis.

A. Christiano, W. Henn, A. Martinez-Mir, 2002, Journal of the American Academy of Dermatology.

Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells

Zongyou Guo, A. Christiano, K. Gledhill, 2015, PloS one.

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Tom R. Gaunt, Manuel A. R. Ferreira, David M. Evans, 2017 .

Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

A. Christiano, C. Higgins, James C. Chen, 2013, Proceedings of the National Academy of Sciences.

FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications.

Iuliana Ionita-Laza, Krzysztof Kiryluk, Valentina Boeva, 2018, American journal of human genetics.

Molecular Genetics of Human Hair Diseases

A. Christiano, A. Zlotogorski, Y. Shimomura, 2008 .

How realistic is cutaneous gene therapy?

L. Goldsmith, T. Jensen, A. Christiano, 1999, Experimental dermatology.

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

S. Madhavan, K. Marder, B. Tycko, 2019, bioRxiv.

Niche Crosstalk: Intercellular Signals at the Hair Follicle

A. Christiano, C. Jahoda, 2011, Cell.

IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy.

C. Drake, A. Christiano, James C. Chen, 2018, Cell systems.

Epidermal Health and Disease Desmosomes : Regulators of Cellular Signaling and Adhesion in Subject Collection The Skin and Its Diseases Immunology and Skin in Health and Disease

Kevin C. Wang, F. Watt, A. Christiano, 2014 .

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

A. Christiano, A. Jong, C. Higgins, 2014, Nature Medicine.

Pumpless microfluidic platform for drug testing on human skin equivalents.

Michael L Shuler, Hasan Erbil Abaci, M. Shuler, 2015, Lab on a chip.

Mammalian tropoelastin: multiple domains of the protein define an evolutionarily divergent amino acid sequence.

R. Pierce, A. Christiano, C. Stolle, 1991, Matrix.

Pharmacologic inhibition of JAK-STAT signaling promotes hair growth

A. Christiano, C. Higgins, James C. Chen, 2015, Science Advances.

The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

A. Christiano, J. Mackenzie, K. Tryggvason, 1986, Human Genetics.

Hair follicle predetermination.

A. Christiano, A. Panteleyev, C. Jahoda, 2001, Journal of cell science.

A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers.

J. McGrath, A. Christiano, A. Irvine, 1998, American journal of human genetics.

Cloning of human type VII collagen. Complete primary sequence of the alpha 1(VII) chain and identification of intragenic polymorphisms.

J. Uitto, A. Christiano, D. Greenspan, 1994, The Journal of biological chemistry.

Pretibial epidermolysis bullosa: genetic linkage to COL7A1 and identification of a glycine-to-cysteine substitution in the triple-helical domain of type VII collagen.

J. Uitto, A. Christiano, J. Y. Lee, 1995, Human molecular genetics.

Molecular basis of recessive dystrophic epidermolysis bullosa: genotype/phenotype correlation in a case of moderate clinical severity.

H. Shimizu, T. Nishikawa, J. Uitto, 1996, The Journal of investigative dermatology.

Characterization of Desmoglein Expression in the Normal Prostatic Gland. Desmoglein 2 Is an Independent Prognostic Factor for Aggressive Prostate Cancer

C. Cordon-Cardo, A. Christiano, M. Castillo-Martin, 2014, PloS one.

Inherited Disorders of the Hair

A. Christiano, M. Kurban, 2013 .

Localized autosomal recessive hypotrichosis due to a frameshift mutation in the desmoglein 4 gene exhibits extensive phenotypic variability within a Pakistani family.

H. Bazzi, A. Christiano, A. Zlotogorski, 2007, The Journal of investigative dermatology.

Broken hearts, woolly hair, and tattered skin: when desmosomal adhesion goes awry.

H. Bazzi, A. Christiano, 2007, Current opinion in cell biology.

Evidence for extensive locus heterogeneity in Naxos disease.

A. Christiano, A. Martinez-Mir, A. Zlotogorski, 2002, The Journal of investigative dermatology.

Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy.

J. R. MacDonald, S. Scherer, J. Beckmann, 2005, American journal of human genetics.

Genome-wide linkage analysis of an autosomal recessive hypotrichosis identi fi es a novel P 2 RY 5 mutation

C. Haynes, G. Lina, D. Gordon, 2008 .

Genome-wide linkage analysis of an autosomal recessive hypotrichosis identifies a novel P2RY5 mutation.

C. Haynes, D. Gordon, L. Shapiro, 2008, Genomics.

Basic Principles of Genetics and Gene Therapy

A. Christiano, L. Kraemer, 2010 .

Inherited disorders of the skin in human and mouse: from development to differentiation.

A. Christiano, R. O’Shaughnessy, 2004, The International journal of developmental biology.

Reprogramming of human hair follicle dermal papilla cells into induced pluripotent stem cells.

A. Christiano, C. Higgins, M. Itoh, 2012, The Journal of investigative dermatology.

Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1.

A. Christiano, M. Wajid, Y. Shimomura, 2011, American journal of human genetics.

Pathomechanisms of immune-mediated alopecia.

A. Christiano, V. Aoki, E. Wang, 2019, International immunology.

Tofacitinib for the treatment of lichen planopilaris: A case series

A. Christiano, L. Bordone, Christine C Yang, 2018, Dermatologic therapy.

JAK Inhibitors for Treatment of Alopecia Areata.

A. Christiano, E. Wang, B. Sallee, 2018, The Journal of investigative dermatology.

Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin.

A. O’Donnell-Luria, J. Cain, A. Christiano, 2020, Developmental biology.

In vivo enhanced expression of patched dampens the sonic hedgehog pathway.

R. Crystal, N. Sato, A. Christiano, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Progress Towards Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA International Research Symposium EB2015

J. Uitto, J. McGrath, A. Christiano, 2015, The Journal of investigative dermatology.

Type VII collagen gene expression by cultured human cells and in fetal skin. Abundant mRNA and protein levels in epidermal keratinocytes.

J. Uitto, A. Christiano, L. Chung, 1992, The Journal of clinical investigation.

Trans‐species hair growth induction by human hair follicle dermal papillae

J. Gillespie, A. Christiano, R. Oliver, 2001, Experimental dermatology.

Reduced Toxicity Conditioning and Allogeneic Hematopoietic Progenitor Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa.

K. Radhakrishnan, J. Uitto, J. McGrath, 2015, The Journal of pediatrics.

Novel molecular therapies for heritable skin disorders.

J. Uitto, J. McGrath, A. Christiano, 2012, The Journal of investigative dermatology.

Genetics of Structural Hair Disorders.

A. Christiano, S. Harel, 2012, The Journal of investigative dermatology.

Cloning of the β3 chain gene (LAMB3) of human laminin 5, a candidate gene in junctional epidermolysis bullosa

R. Burgeson, J. Uitto, A. Christiano, 1995 .

Subject Index Vol. 14, 2001

J. Saurat, C. Elmets, A. Christiano, 2001, Skin Pharmacology and Physiology.

Genetic basis of alopecia areata: a roadmap for translational research.

A. Christiano, L. Petukhova, R. Clynes, 2013, Dermatologic clinics.

Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta.

S. Jimenez, J. Uitto, A. Christiano, 1994, The Journal of clinical investigation.

Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.

A. Christiano, M. Wajid, Y. Shimomura, 2010, American journal of human genetics.

Epitope mapping of type VII collagen. Identification of discrete peptide sequences recognized by sera from patients with acquired epidermolysis bullosa.

J. Uitto, A. Christiano, D. Woodley, 1993, The Journal of clinical investigation.

Patterns of hairless (hr) gene expression in mouse hair follicle morphogenesis and cycling.

A. Christiano, R. Paus, A. Panteleyev, 2000, The American journal of pathology.

Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin

Jessica A. Weber, A. O’Donnell-Luria, J. Cain, 2019, bioRxiv.

The genetic architecture of alopecia areata.

A. Christiano, L. Petukhova, 2013, The journal of investigative dermatology. Symposium proceedings.

Genome-Wide MicroRNA Analysis Implicates miR-30b/d in the Etiology of Alopecia Areata.

M. Nöthen, A. Tafazzoli, A. Christiano, 2017, The Journal of investigative dermatology.

Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis

A. Christiano, Hyunmi Kim, Courtney T. Luke, 2013, Experimental dermatology.

Hairless and NFκB Form a Positive Feedback Loop After UVB and TNFα Stimulation †

A. Christiano, Hyunmi Kim, D. Owens, 2012, Photochemistry and photobiology.

The Effect of Inbreeding on the Distribution of Compound Heterozygotes: A Lesson from Lipase H Mutations in Autosomal Recessive Woolly Hair/Hypotrichosis

S. Hodge, A. Christiano, P. Gorroochurn, 2009, Human Heredity.

Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in the P2RY5 gene

L. Shapiro, A. Christiano, Y. Shimomura, 2009, Experimental dermatology.

Ligand‐independent Regulation of the hairless Promoter by Vitamin D Receptor †

A. Christiano, R. Bauer, A. Engelhard, 2008, Photochemistry and photobiology.

Genetic Hair and Nail Defects

A. Christiano, M. Tadin-Strapps, 2006 .

Hairless contains a novel nuclear matrix targeting signal and associates with histone deacetylase 3 in nuclear speckles.

A. Christiano, K. Djabali, 2004, Differentiation; research in biological diversity.

Recapitulation of the hairless mouse phenotype using catalytic oligonucleotides: implications for permanent hair removal

A. Christiano, P. Cserhalmi-Friedman, A. Panteleyev, 2004, Experimental dermatology.

The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells

A. Christiano, A. Engelhard, A. Christiano, 2004, Experimental dermatology.

Clinical and pathologic correlations in genetically distinct forms of atrichia.

D. Ben-Amitai, A. Christiano, Z. Hochberg, 2003, Archives of dermatology.

Morphological approach to hair disorders.

R. Grimalt, R. Happle, A. Tosti, 2003, The journal of investigative dermatology. Symposium proceedings.

Atrichia with papular lesions resulting from mutations in the rhesus macaque (Macaca mulatta) hairless gene

J. Sundberg, A. Christiano, W. Ahmad, 2002, Laboratory animals.

Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene.

A. Christiano, S. Lyle, G. Cotsarelis, 2001, The Journal of investigative dermatology.

Structural analysis reflects the evolutionary relationship between the human desmocollin gene family members

A. Christiano, W. Ahmad, V. Aita, 2001, Experimental dermatology.

Settling the score on hairless.

A. Christiano, A. Zlotogorski, V. Aita, 2000, The Journal of investigative dermatology.

The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation.

J. Sundberg, A. Christiano, R. Paus, 1999, The American journal of pathology.

Molecular basis for the rhino Yurlovo (hrrhY) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene

J. Sundberg, A. Christiano, R. Paus, 1998, Experimental dermatology.

Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene.

J. Sundberg, A. Christiano, W. Ahmad, 1998, Genomics.

Genomic organization and analysis of the hairless gene in four hypotrichotic rat strains

A. Christiano, Hyunmi Kim, C. Jahoda, 2004, Mammalian Genome.

The molecular basis of congenital atrichia in humans and mice: mutations in the hairless gene.

A. Christiano, W. Ahmad, A. Panteleyev, 1999, The journal of investigative dermatology. Symposium proceedings.

Trans-gender induction of hair follicles

A. Christiano, C. Lawrence, P. Cserhalmi-Friedman, 1999, Nature.

Exposing the human nude phenotype

J. Ott, C. Pignata, D. Gordon, 1999, Nature.

A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.

C. Drake, A. Christiano, A. Ferrante, 2019, Cell stem cell.

Activation of Notch1 in the hair follicle leads to cell-fate switch and Mohawk alopecia.

A. Christiano, D. D. de Berker, A. Panteleyev, 2004, Differentiation; research in biological diversity.

The WNT signalling modulator, Wise, is expressed in an interaction-dependent manner during hair-follicle cycling.

A. Christiano, J. Gautier, C. Jahoda, 2004, The Journal of investigative dermatology.

Glycine substitutions in the triple-helical region of type VII collagen result in a spectrum of dystrophic epidermolysis bullosa phenotypes and patterns of inheritance.

J. Uitto, J. McGrath, A. Christiano, 1996, American journal of human genetics.

Master regulators of infiltrate recruitment in autoimmune disease identified through network-based molecular deconvolution.

A. Christiano, James C. Chen, J. Cerise, 2015, Cell systems.

Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

C. Bieberich, C. Drake, A. D. De Marzo, 2021, Nature Cancer.

Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression

C. Bieberich, C. Drake, A. D. De Marzo, 2019, bioRxiv.

Compound heterozygosity for non-sense and mis-sense mutations in desmoplakin underlies skin fragility/woolly hair syndrome.

J. McGrath, A. Christiano, L. Pulkkinen, 2002, The Journal of investigative dermatology.

Hair follicle disruption facilitates pathogenesis to UVB-induced cutaneous inflammation and basal cell carcinoma development in Ptch(+/-) mice.

Z. Weng, C. Elmets, A. Christiano, 2014, The American journal of pathology.

The genetics of alopecia areata: What's new and how will it help our patients?

A. Christiano, L. Petukhova, R. Clynes, 2011, Dermatologic therapy.

NIPAL4/Ichthyin Is Expressed in the Granular Layer of Human Epidermis and Mutated in Two Pakistani Families with Autosomal Recessive Ichthyosis

A. Christiano, M. Wajid, Y. Shimomura, 2009, Dermatology.

Alopecia areata: Disease characteristics, clinical evaluation, and new perspectives on pathogenesis.

J. Shapiro, A. Christiano, L. Strazzulla, 2018, Journal of the American Academy of Dermatology.

Bullous pemphigoid antigen: cDNA cloning, cellular expression, and evidence for polymorphism of the human gene.

J. Uitto, A. Christiano, K. Nomura, 1990, The Journal of investigative dermatology.

Desmoglein 4 mutations underlie localized autosomal recessive hypotrichosis in humans, mice, and rats.

H. Bazzi, A. Christiano, A. Martinez-Mir, 2005, The journal of investigative dermatology. Symposium proceedings.

A spontaneous mutation in the desmoglein 4 gene underlies hypotrichosis in a new lanceolate hair rat model.

T. Kurtz, H. Bazzi, A. Christiano, 2004, Differentiation; research in biological diversity.

A missense mutation in the cadherin interaction site of the desmoglein 4 gene underlies localized autosomal recessive hypotrichosis.

H. Bazzi, L. Shapiro, A. Christiano, 2005, The Journal of investigative dermatology.

Cloning of the breakpoints of a de novo inversion of chromosome 8, inv (8)(p11.2q23.1) in a patient with Ambras syndrome

T. Gilliam, A. Christiano, D. Warburton, 2004, Cytogenetic and Genome Research.

Alopecia areata

J. Shapiro, A. Christiano, L. Strazzulla, 2017, Nature Reviews Disease Primers.

The Changing Landscape of Alopecia Areata: The Translational Landscape

A. Christiano, E. Wang, 2017, Advances in Therapy.

Classification of pseudoxanthoma elasticum: report of a consensus conference.

M. Lebwohl, V. McKusick, J. Uitto, 1994, Journal of the American Academy of Dermatology.

Genetic linkage of familial granulomatous inflammatory arthritis, skin rash, and uveitis to chromosome 16.

L. Ala‐Kokko, A. Christiano, H. Kuivaniemi, 1996, American journal of human genetics.

Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions.

H. Bazzi, L. Shapiro, A. Christiano, 2006, The Journal of investigative dermatology.

Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo "hairless" rat.

H. Bazzi, A. Christiano, A. Panteleyev, 2004, Differentiation; research in biological diversity.

Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity.

H. Bazzi, A. Christiano, P. Owens, 2008, Developmental biology.

A recurrent intragenic deletion in the desmoglein 4 gene underlies localized autosomal recessive hypotrichosis.

A. Christiano, A. Martinez-Mir, H. Lam, 2004, The Journal of investigative dermatology.

A nonsense mutation in the desmoglein 1 gene underlies striate keratoderma

A. Christiano, J. Frank, A. Martinez-Mir, 2003, Experimental dermatology.

Characterization of the desmosomal cadherin gene family: Genomic organization of two desmoglein genes on human chromosome 18q12

A. Christiano, W. Ahmad, J. Frank, 2001, Experimental dermatology.

Bumps and pumps, SERCA 1999

A. Christiano, M. Peacocke, 1999, Nature Genetics.

Evidence for a Founder Mutation in the Cathepsin C Gene in Three Families with Papillon-Lefèvre Syndrome

A. Christiano, M. Wajid, Y. Shimomura, 2009, Dermatology.

Congenital universal hypertrichosis with deafness and dental anomalies inherited as an X‐linked trait

A. Christiano, A. Martinez-Mir, A. Christiano, 2003, Clinical genetics.

Molecular biology and pathology of human elastin.

J. Rosenbloom, J. Uitto, A. Christiano, 1991, Biochemical Society Transactions.

Analysis of the desmoplakin gene reveals striking conservation with other members of the plakin family of cytolinkers

A. Christiano, W. McLean, K. Green, 1999, Experimental dermatology.

Mutations in the SLURP-1 gene underlie Mal de Meleda in three Pakistani families.

A. Christiano, M. Wajid, Y. Shimomura, 2009, Journal of dermatological science.

A recurrent mutation in the ARS (component B) gene encoding SLURP-1 in Turkish families with mal de Meleda: evidence of a founder effect.

A. Christiano, A. Martinez-Mir, E. Yılmaz, 2003, The Journal of investigative dermatology.

A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome

Anthony P. Monaco, Jouni Uitto, Daniel E. Weeks, 1996, Nature Genetics.

Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis).

A. Christiano, P. Elias, K. Feingold, 2004, The Journal of investigative dermatology.

Frontiers in keratodermas: pushing the envelope.

A. Christiano, A. Christiano, 1997, Trends in genetics : TIG.

Molecular diagnosis of inherited skin diseases: the paradigm of dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, 1996, Advances in dermatology.

Epidermolytic palmoplantar keratoderma in a Hispanic kindred resulting from a mutation in the keratin 9 gene

A. Christiano, P. Cserhalmi-Friedman, I. Warmuth, 2000, Clinical and experimental dermatology.

Epidermolytic hyperkeratosis in a Hispanic family resulting from a mutation in the keratin 1 gene

D. Gordon, A. Christiano, P. Cserhalmi-Friedman, 2000, Clinical and experimental dermatology.

Epidermolytic hyperkeratosis with polycyclic posoriasiform plaques resulting from a mutation in the keratin 1 gene

A. Christiano, A. Christiano, P. Schneiderman, 1999, Experimental dermatology.

A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa

H. Dietz, J. Uitto, A. Christiano, 1993, Nature Genetics.

Prenatal diagnosis for Epidermolysis bullosa: a study of 144 consecutive pregnancies at risk

J. Uitto, A. Christiano, L. Pulkkinen, 2003, Prenatal diagnosis.

Premature termination codon mutations in the type VII collagen gene in recessive dystrophic epidermolysis bullosa result in nonsense-mediated mRNA decay and absence of functional protein.

R. Burgeson, J. Uitto, A. Christiano, 1997, The Journal of investigative dermatology.

Development of Genetic Therapies for the Hemidesmosomal Subtypes of Junctional Epidermolysis Bullosa

A. Christiano, 2000 .

Characterization of 18 new mutations in COL7A1 in recessive dystrophic epidermolysis bullosa provides evidence for distinct molecular mechanisms underlying defective anchoring fibril formation.

C. Bodemer, M. Lathrop, Y. Barrandon, 1997, American journal of human genetics.

Premature termination codons are present on both alleles of the bullous pemphigoid antigen 2/type XVII collagen gene in five Austrian families with generalized atrophic benign epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1997, The Journal of investigative dermatology.

C. Amos, T. Mendoza, A. Christiano, 2013, The journal of investigative dermatology. Symposium proceedings.

Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

A. Christiano, Y. Ramot, A. Zlotogorski, 2015, EBioMedicine.

Mutations in the LIPH gene in three Japanese families with autosomal recessive woolly hair/hypotrichosis.

A. Christiano, Masaaki Ito, Y. Shimomura, 2009, Journal of dermatological science.

Copy Number Variations on Chromosome 4q26–27 Are Associated with Cantu Syndrome

A. Christiano, C. Kim, B. Levy, 2012, Dermatology.

A multi-organ chip with matured tissue niches linked by vascular flow

Carrie L. German, G. Vunjak‐Novakovic, A. Califano, 2022, Nature Biomedical Engineering.

Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata.

A. Christiano, R. Vaughan, J. Cerise, 2016, JCI insight.

Topical JAK Inhibitors for the Treatment of Alopecia Areata and Vitiligo

A. Christiano, E. Wang, J. Harris, 2017, Current Dermatology Reports.

Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers

A. Christiano, J. Cerise, R. Clynes, 2016, Experimental dermatology.

Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization.

E. Lane, R. Ray, S. DeArmond, 1996, Genes & development.

Detection of Novel LAMC 2 Mutations in Herlitz Junctional Epidermolysis Bullosa

J. Uitto, J. McGrath, J. Ortonne, 2007 .

Molecular basis of non‐lethal junctional epidermolysis bullosa: identification of a 38 basepair insertion and a splice site mutation in exon 14 of the LAMB3 gene

R. Burgeson, A. Christiano, P. Cserhalmi-Friedman, 1998, Experimental dermatology.

Identification of a glycine substitution and a splice site mutation in the type VII collagen gene in a proband with mitis recessive dystrophic epidermolysis bullosa

A. Christiano, P. Cserhalmi-Friedman, S. Kárpáti, 1997, Archives of Dermatological Research.

Identification of the LAMB3 hotspot mutation R635X in a Hungarian case of Herlitz junctional epidermolysis bullosa

A. Christiano, Z. Sápi, S. Kárpáti, 1997, Experimental dermatology.

MUTATION‐BASED PRENATAL DIAGNOSIS OF HERLITZ JUNCTIONAL EPIDERMOLYSIS BULLOSA

J. Uitto, J. McGrath, A. Christiano, 1997, Prenatal diagnosis.

Glycine substitution mutations in the type VII collagen gene (COL7A1) in dystrophic epidermolysis bullosa: implications for genetic counseling.

J. Uitto, J. McGrath, A. Christiano, 1997, The Journal of investigative dermatology.

Detection of Novel LAMC2 Mutations in Herlitz Junctional Epidermolysis Bullosa

J. Uitto, J. McGrath, J. Ortonne, 1997, Molecular medicine.

Molecular genetics of the cutaneous basement membrane zone. Perspectives on epidermolysis bullosa and other blistering skin diseases.

J. Uitto, A. Christiano, A. Christiano, 1992, The Journal of clinical investigation.

Mutations in the γ2 chain gene (LAMC2) of kalinin/laminin 5 in the junctional forms of epidermolysis bullosa

J. Uitto, A. Christiano, K. Tryggvason, 1994, Nature Genetics.

A homozygous insertion–deletion in the type VII collagen gene (COL7A1) in Hallopeau–Siemens dystrophic epidermolysis bullosa

Y. Barrandon, J. Uitto, A. Christiano, 1993, Nature Genetics.

Junctional Forms of Epidermolysis Bullosa

J. Uitto, A. Christiano, 1998 .

Identification of the glycine‐to‐arginine substitution G2043R in type VII collagen in a family with dominant dystrophic epidermolysis bullosa from Hungary

A. Christiano, P. Cserhalmi-Friedman, S. Kárpáti, 1997, Experimental dermatology.

Premature termination codon mutations in the type VII collagen gene (COL7A1) underlie severe recessive dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, A. Hovnanian, 1995, Proceedings of the Association of American Physicians.

DNA based molecular analysis in the rapid diagnosis of Herlitz junctional epidermolysis bullosa

A. Christiano, P. Cserhalmi-Friedman, K. Yeboa, 2001, Clinical and experimental dermatology.

Identification of a Founder Mutation in the Protoporphyrinogen Oxidase Gene in Variegate Porphyria Patients from Chile

A. Christiano, W. Ahmad, J. Frank, 2001, Human Heredity.

The Genetic Bases of the Porphyrias

A. Christiano, J. Frank, 1998, Skin Pharmacology and Physiology.

Variegate porphyria: identification of a nonsense mutation in the protoporphyrinogen oxidase gene.

A. Christiano, H. Merk, J. Frank, 1998, The Journal of investigative dermatology.

Molecular basis of variegate porphyria: a de novo insertion mutation in the protoporphyrinogen oxidase gene

A. Christiano, D. Bickers, H. Tsou, 1996, Human Genetics.

Compound heterozygosity for COL7A1 mutations in twins with dystrophic epidermolysis bullosa: a recessive paternal deletion/insertion mutation and a dominant negative maternal glycine substitution result in a severe phenotype.

R. Burgeson, J. Uitto, A. Christiano, 1996, American journal of human genetics.

Influence of the second COL7A1 mutation in determining the phenotypic severity of recessive dystrophic epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1996, The Journal of investigative dermatology.

A common insertion mutation in COL7A1 in two Italian families with recessive dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, M. Paradisi, 1996, The Journal of investigative dermatology.

Molecular basis of the dystrophic and junctional forms of epidermolysis bullosa: mutations in the type VII collagen and kalinin (laminin 5) genes.

J. Uitto, A. Christiano, L. Pulkkinen, 1994, The Journal of investigative dermatology.

De novo mutations in monilethrix

A. Christiano, Jack Green, R. Sinclair, 2003, Experimental dermatology.

Complex cytogenetic rearrangement of chromosome 8q in a case of Ambras syndrome.

A. Christiano, B. Levy, D. Warburton, 2001, American journal of medical genetics.

Novel compound heterozygous mutations in the desmoplakin gene cause hair shaft abnormalities and culminate in lethal cardiomyopathy

A. Christiano, A. Fryer, E. Ladusans, 2014, Clinical and experimental dermatology.

Mutations in the desmoglein 1 gene in five Pakistani families with striate palmoplantar keratoderma.

A. Christiano, L. Kraemer, M. Wajid, 2009, Journal of dermatological science.

Mutations in the lipase H gene underlie autosomal recessive woolly hair/hypotrichosis.

L. Shapiro, A. Christiano, M. Wajid, 2009, The Journal of investigative dermatology.

Striate palmoplantar keratoderma resulting from a frameshift mutation in the desmoglein 1 gene.

A. Christiano, M. Wajid, J. Lubetkin, 2007, Journal of dermatological science.

The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome.

A. Christiano, M. Duvic, J. Curry, 2011, Journal of the American Academy of Dermatology.

A recurrent homozygous nonsense mutation within the LAMA3 gene as a cause of Herlitz junctional epidermolysis bullosa in patients of Pakistani ancestry: evidence for a founder effect.

J. Uitto, J. McGrath, A. Christiano, 1996, The Journal of investigative dermatology.

Targeting the JAK/STAT3 pathway with Ruxolitinib in a mouse model of recessive dystrophic epidermolysis bullosa-squamous cell carcinoma.

Zongyou Guo, A. Christiano, J. Jacków, 2020, The Journal of investigative dermatology.

transplantation evaluation of immunologic reconstitution after bone marrow Human equivalent of the mouse Nude/SCID phenotype: long-term

A. Masci, C. Pignata, L. Racioppi, 2013 .

Cloning of the beta 3 chain gene (LAMB3) of human laminin 5, a candidate gene in junctional epidermolysis bullosa.

R. Burgeson, J. Uitto, A. Christiano, 1995, Genomics.

Cord Blood‐Derived Stem Cells Suppress Fibrosis and May Prevent Malignant Progression in Recessive Dystrophic Epidermolysis Bullosa

J. McGrath, A. Christiano, M. Cairo, 2018, Stem cells.

CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata

A. Christiano, L. Petukhova, J. Cerise, 2016, The Journal of Immunology.

Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3

A. Christiano, A. Martinez-Mir, A. Zlotogorski, 2014 .

Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA).

A. Christiano, R. Clynes, J. Mackay-Wiggan, 2016, Journal of the American Academy of Dermatology.

649 Gut microbiota plays a role in the development of alopecia areata

A. Christiano, Z. Dai, L. Nair, 2017 .

CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

H. Abaci, Zongyou Guo, A. Christiano, 2019, Proceedings of the National Academy of Sciences.

Mutations in R-spondin 4 (RSPO4) underlie inherited anonychia.

D. Kelsell, H. Bazzi, Y. Ishii, 2008, The Journal of investigative dermatology.

Sabinas syndrome in monozygotic twins

A. Christiano, J. Ocampo-Candiani, J. Salas-Alanis, 2009, Clinical and experimental dermatology.

Termination Codons on Both Alleles of the Type VIl Collagen Gene ( COL 7 A 1 ) in Three Brothers with Recessive Dystrophic Epidermolysis Bullosa

J. Uitto, A. Christiano, D. Greenspan, 2013 .

Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata

A. Christiano, R. Gund, 2022, Autophagy.

A to G polymorphism in ELN gene.

J. Rosenbloom, A. Christiano, H. Kuivaniemi, 1991, Nucleic acids research.

Rapid prenatal diagnosis of sickle cell diseases using oligonucleotide ligation assay coupled with laser‐induced capillary fluorescence detection

A. Christiano, S. Piomelli, Stephen Brown, 2002, Prenatal diagnosis.

Genomic Organization of Mouse Desmocollin Genes Reveals Evolutionary Conservation

A. Christiano, R. Bauer, A. Kljuic, 2004, DNA sequence : the journal of DNA sequencing and mapping.

Workshop on pseudoxanthoma elasticum: molecular biology and pathology of the elastic fibers. Jefferson Medical College, Philadelphia, Pennsylvania, June 10, 1992.

M. Lebwohl, J. Uitto, A. Christiano, 1992, The Journal of investigative dermatology.

Human Cord Blood-Derived Unrestricted Somatic Stem Cells Promote Wound Healing and have Therapeutic Potential for Patients with Recessive Dystrophic Epidermolysis Bullosa

A. Christiano, M. Cairo, M. Itoh, 2014, Cell transplantation.

Molecular analysis of the human laminin alpha3a chain gene (LAMA3a): a strategy for mutation identification and DNA-based prenatal diagnosis in Herlitz junctional epidermolysis bullosa.

J. Uitto, A. Christiano, L. Pulkkinen, 1998, Laboratory investigation; a journal of technical methods and pathology.

Compound heterozygosity for a dominant glycine substitution and a recessive internal duplication mutation in the type XVII collagen gene results in junctional epidermolysis bullosa and abnormal dentition.

J. R. McMillan, J. Uitto, J. McGrath, 1996, The American journal of pathology.

Differential cytokine modulation of the genes LAMA3, LAMB3, and LAMC2, encoding the constitutive polypeptides, α3, β3, and γ2, of human laminin 5 in epidermal keratinocytes

J. Uitto, A. Christiano, A. Mauviel, 1995, FEBS letters.

Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis

V. Jobanputra, Yufeng Shen, Yujun Han, 2013, Proceedings of the National Academy of Sciences.

The genetics of human skin disease.

A. Christiano, G. Destefano, 2014, Cold Spring Harbor perspectives in medicine.

Strategy for identification of sequence variants in COL7A1 and a novel 2‐bp deletion mutation in recessive dystrophic epidermolysis bullosa

J. Uitto, A. Christiano, D. Greenspan, 1997, Human mutation.

A homozygous nonsense mutation in the alpha 3 chain gene of laminin 5 (LAMA3) in Herlitz junctional epidermolysis bullosa: prenatal exclusion in a fetus at risk.

C. Rodeck, J. Uitto, J. McGrath, 1995, Genomics.

Genetic basis of lethal junctional epidermolysis bullosa in an affected fetus: Implications for prenatal diagnosis in one family

C. Rodeck, J. R. McMillan, J. Uitto, 1995, Prenatal diagnosis.

A novel homozygous nonsense mutation in the LAMC2 gene in patients with the Herlitz junctional epidermolysis bullosa.

J. Uitto, J. Ortonne, A. Christiano, 1994, Human molecular genetics.

Recurrent nonsense mutations within the type VII collagen gene in patients with severe recessive dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, A. Hovnanian, 1994, American journal of human genetics.

Premature termination codons in the type VII collagen gene (COL7A1) underlie severe, mutilating recessive dystrophic epidermolysis bullosa.

E. Bauer, J. Uitto, A. Christiano, 1994, Genomics.

Dominant dystrophic epidermolysis bullosa: identification of a Gly-->Ser substitution in the triple-helical domain of type VII collagen.

J. Uitto, A. Christiano, M. Ryynänen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Adipocytes in Skin Health and Disease

F. Watt, A. Christiano, G. Petrof, 2014 .

A locus for autosomal recessive hypodontia with associated dental anomalies maps to chromosome 16q12.1.

J. Ott, A. Christiano, W. Ahmad, 1998, American journal of human genetics.

Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa.

J. Uitto, J. Ortonne, A. Christiano, 1995, Genomics.

Stem Cells in the Epidermis

A. Christiano, R. O’Shaughnessy, 2001, Skin Pharmacology and Physiology.

The dermal-epidermal junction.

R. Burgeson, A. Christiano, A M Christiano, 1997, Current opinion in cell biology.

Cloning of the Gene for Human Pemphigus Vulgaris Antigen (Desmoglein 3), a Desmosomal Cadherin

J. Uitto, A. Christiano, K. Tamai, 1996, The Journal of Biological Chemistry.

Mutations in the 180–kD bullous pemphigoid antigen (BPAG2), a hemidesmosomal transmembrane collagen (COL17A1), in generalized atrophic benign epidermolysis bullosa

J. R. McMillan, J. Uitto, J. McGrath, 1995, Nature Genetics.

Desmoglein 4 in Hair Follicle Differentiation and Epidermal Adhesion Evidence from Inherited Hypotrichosis and Acquired Pemphigus Vulgaris

J. Ott, T. Gilliam, J. Sundberg, 2003, Cell.

Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias

R. Sivamani, J. Sundberg, A. Christiano, 2018, Experimental dermatology.

Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata.

T. Gilliam, J. Ott, C. Haynes, 2007, American journal of human genetics.

High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata.

A. Christiano, M. Duvic, R. Clynes, 2018, JCI insight.

Novel therapies for alopecia areata: The era of rational drug development

A. Christiano, Z. Dai, E. Wang, 2017, The Journal of allergy and clinical immunology.

Hair on a gene string: recent advances in understanding the molecular genetics of hair loss

A. Christiano, A. Irvine, A. Christiano, 2001, Clinical and experimental dermatology.

Alopecia areata.

J. Sundberg, A. Christiano, A. Messenger, 1977, British medical journal.

Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82

I. Ionita-Laza, A. Christiano, S. Gelfman, 2022, Nature communications.

Generation of 3D Skin Equivalents Fully Reconstituted from Human Induced Pluripotent Stem Cells (iPSCs)

Angela M. Christiano, Noriko Umegaki-Arao, Zongyou Guo, 2013, PloS one.

Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia.

A. Christiano, C. Higgins, 2014, Regenerative medicine.

Alopecia areata is a medical disease.

J. Shapiro, A. Christiano, B. King, 2018, Journal of the American Academy of Dermatology.

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

Annette Lee, P. Gregersen, C. Amos, 2010, Nature.

Revised classification system for inherited epidermolysis bullosa: Report of the Second International Consensus Meeting on diagnosis and classification of epidermolysis bullosa.

E. Bauer, H. Shimizu, J. Uitto, 2000, Journal of the American Academy of Dermatology.

Genetic basis of dominantly inherited transient bullous dermolysis of the newborn: a splice site mutation in the type VII collagen gene.

J. Uitto, A. Christiano, J. Fine, 1997, The Journal of investigative dermatology.

Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.

M. Lebwohl, J. Uitto, A. Christiano, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing

H. Abaci, Zongyou Guo, A. Christiano, 2020, Scientific Reports.

Identification of a locus for type I punctate palmoplantar keratoderma on chromosome 15q22–q24

T. Gilliam, J. Liu, A. Grunn, 2003, Journal of medical genetics.

Germline fumarate hydratase mutations in families with multiple cutaneous and uterine leiomyomata.

B. Glaser, D. Gordon, A. Christiano, 2003, The Journal of investigative dermatology.

Disruption of P2RY5, an orphan G protein–coupled receptor, underlies autosomal recessive woolly hair

D. Gordon, L. Shapiro, Y. Ishii, 2008, Nature Genetics.

Nail dystrophy associated with a heterozygous mutation of the nude/SCID human FOXN1 (WHN) gene.

C. Pignata, A. Christiano, J. Frank, 2005, Archives of dermatology.

Molecular basis for the dystrophic forms of epidermolysis bullosa: mutations in the type VII collagen gene

J. Uitto, A. Christiano, 2004, Archives of Dermatological Research.

Recurrent nonsense mutations within the type VII collagen gene in patients with severe recessive dystrophic epidermolysis bullosa.

M Goossens, J. Uitto, A. Christiano, 1994, American journal of human genetics.

nine Chapter fifty-four Basic Principles of Genetics

A. Christiano, A. Martinez-Mir, 2012 .

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells.

J. Wagner, J. Tolar, J. Uitto, 2009, Blood.

Identification of a de novo glycine substitution in the type VII collagen gene in a proband with mild dystrophic epidermolysis bullosa

A. Christiano, W. Ahmad, P. Cserhalmi-Friedman, 1999, Experimental dermatology.

Novel and de novo glycine substitution mutations in the type VII collagen gene (COL7A1) in dystrophic epidermolysis bullosa: implications for genetic counseling.

J. Uitto, A. Christiano, L. Pulkkinen, 1998, The Journal of investigative dermatology.

Clinicopathological correlations of compound heterozygous COL7A1 mutations in recessive dystrophic epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1996, The Journal of investigative dermatology.

Genetic basis of Bart's syndrome: a glycine substitution mutation in type VII collagen gene.

J. Uitto, A. Christiano, E. Epstein, 1996, The Journal of investigative dermatology.

Structural organization of the human type VII collagen gene (COL7A1), composed of more exons than any previously characterized gene.

J. Uitto, A. Christiano, D. Greenspan, 1994, Genomics.

Biology and genetics of hair.

A. Christiano, Y. Shimomura, 2010, Annual review of genomics and human genetics.

Hoxa4 expression in developing mouse hair follicles and skin

A. Christiano, D. Wolgemuth, A. Panteleyev, 2000, Mechanisms of Development.

Hair follicle stem cells.

T. Sun, M. Akiyama, Y. Barrandon, 2003, The journal of investigative dermatology. Symposium proceedings.

An unusual case of infiltrating basal cell carcinoma.

A. Christiano, D. Bickers, J. Salas-Alanis, 2011, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

Immunohistochemical, ultrastructural, and molecular features of Kindler syndrome distinguish it from dystrophic epidermolysis bullosa.

R. Burgeson, H. Shimizu, T. Nishikawa, 1997, Archives of dermatology.

First trimester DNA‐based exclusion of recessive dystrophic epidermolysis bullosa from chorionic villus sampling

C. Rodeck, J. Uitto, J. McGrath, 1996, The British journal of dermatology.

Altered laminin 5 expression due to mutations in the gene encoding the beta 3 chain (LAMB3) in generalized atrophic benign epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1995, The Journal of investigative dermatology.

Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the γ2 subunit of nicein/kalinin (LAMININ–5)

J. Uitto, J. Ortonne, A. Christiano, 1994, Nature Genetics.

Inherited epidermolysis bullosa. Clinical features, molecular genetics, and pathoetiologic mechanisms.

J. Uitto, A. Christiano, 1993, Dermatologic clinics.

The molecular genetics of dystrophic epidermolysis bullosa.

A. Christiano, A. Hovnanian, J. Vitto, 1993, Archives of dermatology.

Heterogeneity of mutations in the type VII collagen gene (COL7A1) in different forms of dystrophic epidermolysis bullosa

J. Uitto, A. Christiano, A. Hovnanian, 1994 .

DNA-based prenatal diagnosis of heritable skin diseases.

J. Uitto, A. Christiano, A. Christiano, 1993, Archives of dermatology.

Dystrophic forms of epidermolysis bullosa.

J. Uitto, A. Christiano, A. Christiano, 1993, Seminars in dermatology.

Polymorphism of the human genome: markers for genetic linkage analyses in heritable diseases of the skin.

J. Uitto, A. Christiano, 1992, The Journal of investigative dermatology.

PCR-based detection of two exonic polymorphisms in the human type VII collagen gene (COL7A1) at 3p21.1.

J. Uitto, A. Christiano, A. Hovnanian, 1992, Genomics.

The large non-collagenous domain (NC-1) of type VII collagen is amino-terminal and chimeric. Homology to cartilage matrix protein, the type III domains of fibronectin and the A domains of von Willebrand factor.

R. Burgeson, J. Uitto, A. Christiano, 1992, Human molecular genetics.

Molecular biology and pathology of type VII collagen *

J. Uitto, A. Christiano, A. Christiano, 1992, Experimental dermatology.

Compound heterozygosity for nonsense ans missense mutations in the LAMB3 gene in nonlethal junctional epidermolysis bullosa.

J. Uitto, A. Christiano, L. Pulkkinen, 1996, The Journal of investigative dermatology.

A homozygous deletion mutation in the gene encoding the 180-kDa bullous pemphigoid antigen (BPAG2) in a family with generalized atrophic benign epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1996, The Journal of investigative dermatology.

DNA-based prenatal diagnosis of generalized recessive dystrophic epidermolysis bullosa in six pregnancies at risk for recurrence.

J. Terwilliger, C. Bodemer, A. Christiano, 1995, The Journal of investigative dermatology.

Collagen VII in severe recessive dystrophic epidermolysis bullosa: expression of mRNA but lack of intact protein product in skin and cutaneous cells in vitro.

J. Uitto, A. Christiano, L. Bruckner-Tuderman, 1994, The Journal of investigative dermatology.

Prenatal Diagnosis for Recessive Dystrophic Epidermolysis Bullosa in 10 Families by Mutation and Haplotype Analysis in the Type VII Collagen Gene (COL7A1)

H. Shimizu, J. Uitto, A. Christiano, 1996, Molecular medicine.

Genomic profiling of late‐onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome

E. Dermitzakis, L. French, S. Nikolaev, 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.

Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model.

Holly M. Golecki, Benjamin D. Pope, S. Hoerstrup, 2018, Biomaterials.

Nothing but skin and bone.

A. Christiano, F. Ross, 2006, The Journal of clinical investigation.

FGF5 is a crucial regulator of hair length in humans

L. Shapiro, A. Christiano, E. Drill, 2014, Proceedings of the National Academy of Sciences.

Molecular basis of variegate porphyria: a missense mutation in the protoporphyrinogen oxidase gene.

A. Christiano, M. Poh-Fitzpatrick, J. Frank, 1998, Journal of medical genetics.

Homozygous variegate porphyria: identification of mutations on both alleles of the protoporphyrinogen oxidase gene in a severely affected proband.

J. McGrath, R. Graham, A. Christiano, 1998, The Journal of investigative dermatology.

Erythropoietic protoporphyria: four novel frameshift mutations in the ferrochelatase gene.

A. Christiano, S. Piomelli, M. Poh-Fitzpatrick, 1997, The Journal of investigative dermatology.

Induced pluripotent stem cells from human revertant keratinocytes for the treatment of epidermolysis bullosa

Zongyou Guo, A. Christiano, B. Levy, 2014, Science Translational Medicine.

Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.

J. Ko, A. Christiano, B. King, 2016, JCI insight.

The functions of laminins: lessons from in vivo studies.

R. Burgeson, E. Engvall, A. Christiano, 1996, Matrix biology : journal of the International Society for Matrix Biology.

Molecular signatures define alopecia areata subtypes and transcriptional biomarkers

A. Christiano, M. Duvic, James C. Chen, 2016, EBioMedicine.

Regulatory network analysis defines unique drug mechanisms of action and facilitates patient-drug matching in alopecia areata clinical trials

A. Christiano, James C. Chen, Z. Dai, 2021, Computational and structural biotechnology journal.

Department of Clinical Chemistry University of Helsinki MOLECULAR GENETICS OF AUTOSOMAL RECESSIVE CONGENITAL ICHTHYOSIS

A. Palotie, L. Ala‐Kokko, A. Christiano, 2000 .

Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling.

H. Bazzi, A. Christiano, C. Jahoda, 2008, Gene expression patterns : GEP.

Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells

E. Lumpkin, H. Abaci, Zongyou Guo, 2021, Bioengineering & translational medicine.

Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation.

H. Bazzi, A. Christiano, Raphael Kopan, 2009, Differentiation; research in biological diversity.

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex

A. Brivanlou, B. Barres, A. Christiano, 2010, Nature.

KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin

Angela M. Christiano, H. Bazzi, A. Christiano, 2009, Development.

A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice.

J. Sundberg, A. Christiano, D. Warburton, 2008, Human molecular genetics.

The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis.

H. Bazzi, A. Christiano, C. Jahoda, 2007, Developmental biology.

The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

D. Kelsell, Y. Ishii, A. Christiano, 2006, Nature Genetics.

Abnormal cornified cell envelope formation in mutilating palmoplantar keratoderma unrelated to epidermal differentiation complex.

M. Akiyama, H. Shimizu, A. Christiano, 1998, The Journal of investigative dermatology.

The molecular pathology of progressive symmetric erythrokeratoderma: a frameshift mutation in the loricrin gene and perturbations in the cornified cell envelope.

R. Friedman, J. McGrath, A. Christiano, 1997, American journal of human genetics.

Ancestral patterns of recessive dystrophic epidermolysis bullosa mutations in Hispanic populations suggest sephardic ancestry

Christopher R. Gignoux, F. Montinaro, M. Metspalu, 2021, American journal of medical genetics. Part A.

Sequential Loss of Two Neighboring Exons of the Tropoelastin Gene During Primate Evolution

M. Stoneking, M. Batzer, A. Christiano, 1999, Journal of Molecular Evolution.

Integrin β4 mutations associated with junctional epidermolysis bullosa with pyloric atresia

J. Uitto, J. Ortonne, A. Christiano, 1995, Nature Genetics.

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.

B. Tycko, A. Dwork, J. Vonsattel, 2016, American journal of human genetics.

Genomewide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with MCHR2

M. Nöthen, S. Moebus, S. Heilmann-Heimbach, 2017, Experimental dermatology.

FUN-LDA: A LATENT DIRICHLET ALLOCATION MODEL FOR PREDICTING TISSUE-SPECIFIC FUNCTIONAL EFFECTS OF NONCODING VARIATION

Iuliana Ionita-Laza, Krzysztof Kiryluk, Valentina Boeva, 2016, bioRxiv.

TISSUE-SPECIFIC FUNCTIONAL EFFECT PREDICTION OF GENETIC VARIATION AND APPLICATIONS TO COMPLEX TRAIT GENETICS

Iuliana Ionita-Laza, Krzysztof Kiryluk, Joseph D. Buxbaum, 2016 .

The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases.

J. Ott, D. Teng, S. Tavtigian, 1997, American journal of human genetics.

Germline fumarate hydratase mutations and evidence for a founder mutation underlying multiple cutaneous and uterine leiomyomata.

B. Glaser, E. Sprecher, D. Gordon, 2005, Journal of the American Academy of Dermatology.

Multiple cutaneous and uterine leiomyomas: refinement of the genetic locus for multiple cutaneous and uterine leiomyomas on chromosome 1q42.3-43.

J. Ott, D. Gordon, A. Christiano, 2002, The Journal of investigative dermatology.

Site-specific genome editing for correction of induced pluripotent stem cells derived from dominant dystrophic epidermolysis bullosa

Zongyou Guo, A. Christiano, Zongyou Guo, 2016, Proceedings of the National Academy of Sciences.

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis.

A. Christiano, J. Cerise, R. Clynes, 2018, The Journal of investigative dermatology.

Absence of R42X and R635X mutations in the LAMB3 gene in 12 Japanese patients with junctional epidermolysis bullosa

R. Burgeson, H. Shimizu, T. Saida, 1997, Archives of Dermatological Research.

Mutational hotspots in the LAMB3 gene in the lethal (Herlitz) type of junctional epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1996, Human molecular genetics.

A homozygous nonsense mutation in the beta 3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa.

R. Burgeson, J. Uitto, A. Christiano, 1994, Genomics.

Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells

A. Christiano, M. Cairo, M. Itoh, 2011, Proceedings of the National Academy of Sciences.

Molecular pathology of the elastic fibers.

J. Uitto, A. Christiano, 1994, The Journal of investigative dermatology.

Extensive alternate exon usage at the 5' end of the sheep tropoelastin gene.

A. Christiano, L. Sandberg, C. Boyd, 1995, Matrix biology : journal of the International Society for Matrix Biology.

Trps1 and Its Target Gene Sox9 Regulate Epithelial Proliferation in the Developing Hair Follicle and Are Associated with Hypertrichosis

A. Christiano, B. Levy, Katherine A. Fantauzzo, 2012, PLoS genetics.

The Role of MMAC 1 Mutations in Early-Onset Breast Cancer : Causative in Association with Cowden Syndrome and Excluded in BRCA 1-Negative Cases

D. Teng, S. Tavtigian, C. Eng, 2006 .

Efficacy of Human Placental‐Derived Stem Cells in Collagen VII Knockout (Recessive Dystrophic Epidermolysis Bullosa) Animal Model

J. McGrath, A. Christiano, M. Cairo, 2018, Stem cells translational medicine.

A 30 kb deletion within the elastin gene results in familial supravalvular aortic stenosis.

S. Thibodeau, K. Csiszȧr, D. Driscoll, 1995, Human molecular genetics.

Founder mutations in the lipase h gene in families with autosomal recessive woolly hair/hypotrichosis.

A. Christiano, R. Rice, A. Zlotogorski, 2009, The Journal of investigative dermatology.

Childhood alopecia areata—Data from the National Alopecia Areata Registry

A. Christiano, M. Duvic, M. Hordinsky, 2018, Pediatric dermatology.

Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy

A. Christiano, S. Sanna-Cherchi, M. Verbitsky, 2020, Experimental dermatology.

A semi-supervised model to predict regulatory effects of genetic variants at single nucleotide resolution using massively parallel reporter assays.

I. Ionita-Laza, A. Christiano, L. Petukhova, 2021, Bioinformatics.

Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth

V. Jobanputra, A. Christiano, B. Levy, 2014, PLoS genetics.

Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia.

A. Christiano, M. Wajid, Y. Shimomura, 2010, The Journal of investigative dermatology.

A Common Founder Mutation in the EDA-A1 Gene in X-Linked Hypodontia

A. Christiano, M. Wajid, Y. Shimomura, 2010, Dermatology.

A Nonsense Mutation in the SCN9A Gene in Congenital Insensitivity to Pain

A. Christiano, M. Wajid, Y. Shimomura, 2010, Dermatology.

Mutations in the Laminin 5 LAMB3 Gene in Generalized Atrophic Benign Epidermolysis Bullosa

J. Uitto, A. Christiano, J. A. McGarth, 1995 .

Human leukocyte antigen class II alleles are associated with risk of alopecia areata.

M. de Andrade, A. Christiano, Q. Wei, 2008, The Journal of investigative dermatology.

Alopecia areata registry: an overview.

A. Christiano, M. Duvic, M. Hordinsky, 2003, The journal of investigative dermatology. Symposium proceedings.

The Charles River "hairless" rat mutation is distinct from the hairless mouse alleles.

A. Christiano, A. Panteleyev, 2001, Comparative medicine.

Variegate Porphyria: Past, Present and Future

A. Christiano, J. Frank, 1998, Skin Pharmacology and Physiology.

Demystification of Chester porphyria: a nonsense mutation in the Porphobilinogen Deaminase gene.

A. Christiano, J. Connor, H. Merk, 2006, Physiological research.

PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer

C. Cordon-Cardo, A. Christiano, M. Castillo-Martin, 2015, Cancer medicine.

Keratin 71 mutations: from water dogs to woolly hair.

A. Christiano, S. Harel, 2012, The Journal of investigative dermatology.

Genetic linkage studies in alopecia areata.

J. Ott, D. Gordon, A. Christiano, 2003, The journal of investigative dermatology. Symposium proceedings.

Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis

A. Christiano, Katherine A. Fantauzzo, 2012, Development.

Loss of Hairless Confers Susceptibility to UVB-Induced Tumorigenesis via Disruption of NF-kappaB Signaling

A. Christiano, Xiuwei Tang, A. Kim, 2012, PloS one.

A spectrum of novel mutations in the protoporphyrinogen oxidase gene in 13 families with variegate porphyria.

A. Christiano, D. Bickers, K. Anderson, 2001, The Journal of investigative dermatology.

Erythropoietic protoporphyria: identification of novel mutations in the ferrochelatase gene and comparison of biochemical markers versus molecular analysis as diagnostic strategies.

A. Christiano, W. Ahmad, M. Poh-Fitzpatrick, 1999, Journal of investigative medicine : the official publication of the American Federation for Clinical Research.

Ambras syndrome in a Korean patient with balanced pericentric inversion (8)(p11.2q24.2).

A. Christiano, J. Choi, Juwon Kim, 2010, Journal of dermatological science.

Expression patterns of the transcription factor AP-2alpha during hair follicle morphogenesis and cycling.

A. Christiano, P. Mitchell, R. Paus, 2003, The Journal of investigative dermatology.

Identification of mutations in the transgluataminase 1 gene in lamellar ichthyosis

A. Christiano, H. Lam, P. Cserhalmi-Friedman, 1999, Experimental dermatology.

Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing

H. Abaci, Zongyou Guo, A. Christiano, 2020, Scientific Reports.

63,100-element oligonucleotide array activation revealed by profiling of psoriasis on the Novel mechanisms of T-cell and dendritic cell

X. Zhou, M. Kao, M. Chance, 2015 .

Genetic basis of Bart's syndrome: a glycine substitution mutation in the type VII collagen gene.

J. Uitto, A. Christiano, E. Epstein, 1996, The Journal of investigative dermatology.

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle

Lawrence Shapiro, Yutaka Shimomura, L. Shapiro, 2008, Development.

Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.

A. Sette, A. Christiano, S. Paul, 2018, The journal of investigative dermatology. Symposium proceedings.

Whole-exome sequencing in a single proband reveals a mutation in the CHST8 gene in autosomal recessive peeling skin syndrome.

A. Christiano, M. Wajid, Y. Shimomura, 2012, Genomics.

Search for susceptibility genes in alopecia areata.

A. Christiano, A. Martinez-Mir, A. Zlotogorski, 2005, The journal of investigative dermatology. Symposium proceedings.

Hairless is translocated to the nucleus via a novel bipartite nuclear localization signal and is associated with the nuclear matrix.

A. Christiano, V. Aita, K. Djabali, 2001, Journal of cell science.

The lanceolate hair rat phenotype results from a missense mutation in a calcium coordinating site of the desmoglein 4 gene.

Neil Crossley, Lawrence Shapiro, L. Shapiro, 2004, Genomics.

The bulge is the source of cellular renewal in the sebaceous gland of mouse skin

A. Christiano, R. Paus, A. Panteleyev, 2000, Archives of Dermatological Research.

Predominance of the recurrent mutation R635X in the LAMB3 gene in European patients with Herlitz junctional epidermolysis bullosa has implications for mutation detection strategy.

J. Uitto, J. McGrath, J. Ortonne, 1997, The Journal of investigative dermatology.

Identification of Distinct Mutations in AAGAB in Families with Type 1 Punctate Palmoplantar Keratoderma

A. Christiano, A. Martinez-Mir, A. Zlotogorski, 2014, The Journal of investigative dermatology.

Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I protein of human ubiquinol-cytochrome c reductase.

J. Uitto, A. Christiano, D. Greenspan, 1993, The Journal of biological chemistry.

Multiple familial cutaneous glomangioma: a pedigree of 4 generations and critical analysis of histologic and genetic differences of glomus tumors.

S. Goerdt, A. Christiano, W. Ahmad, 2000, Journal of the American Academy of Dermatology.

Shedding Light on Alopecia Areata in Pediatrics: A Retrospective Analysis of Comorbidities in Children in the National Alopecia Areata Registry

A. Christiano, L. Petukhova, Rachel E. Reingold, 2017, Pediatric dermatology.

Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata

A. Christiano, Yuqian Chang, Z. Dai, 2021, JCI insight.

Functional interpretation of genome-wide association study evidence in alopecia areata

A. Christiano, L. Petukhova, 2015, The Journal of investigative dermatology.

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

M. Daly, Annette Lee, P. Gregersen, 2015, Nature Communications.

[Mutation in the ED1, Ala349Thr in a patient with X-linked hypohidrotic ectodermal dysplasia].

A. Christiano, J. Salas-Alanis, M. Kurban, 2011, Revista medica de Chile.

Building a microphysiological skin model from induced pluripotent stem cells

S. Sia, Zongyou Guo, A. Christiano, 2013, Stem Cell Research & Therapy.

EB simplex superficialis resulting from a mutation in the type VII collagen gene.

J. Ott, T. Gilliam, Jianjun Liu, 2002, The Journal of investigative dermatology.

Identification of Two Novel Human Acyl-CoA Wax Alcohol Acyltransferases

H. Bazzi, A. Christiano, M. Padamsee, 2005, Journal of Biological Chemistry.

Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures

M. Lako, A. Christiano, C. Higgins, 2018, Stem cells international.

Epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma). Genetic linkage to chromosome 12q in the region of the type II keratin gene cluster.

J. Uitto, A. Christiano, L. Pulkkinen, 1993, The Journal of clinical investigation.

Multifaceted role of hair follicle dermal cells in bioengineered skins

J. Garlick, A. Christiano, C. Higgins, 2017, The British journal of dermatology.

Tissue engineering of human hair follicles using a biomimetic developmental approach

H. Abaci, Zongyou Guo, A. Coffman, 2018, Nature Communications.

Hairless is a histone H3K9 demethylase

L. Shapiro, A. Christiano, Hyunmi Kim, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Acne chlorina and acne vulgaris – casual likeness or causal homology?

A. Christiano, A. Panteleyev, T. Rosenbach, 2000, Archives of Dermatological Research.

Restoration of open reading frame resulting from skipping of an exon with an internal deletion in the COL7A1 gene.

H. Dietz, J. McGrath, A. Christiano, 1998, Laboratory investigation; a journal of technical methods and pathology.

Recurrent mutations in the type VII collagen gene (COL7A1) in patients with recessive dystrophic epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1997, The Journal of investigative dermatology.

Interaction of hairless and thyroid hormone receptor is not involved in the pathogenesis of atrichia with papular lesions

D. Ben-Amitai, A. Christiano, A. Metzker, 2004, Experimental dermatology.

STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis

C. Prives, A. Christiano, S. Rokudai, 2018, Proceedings of the National Academy of Sciences.

Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice

A. Christiano, Yuqian Chang, L. Petukhova, 2021, Science Advances.

Structural analysis and mutation detection strategy for the human LAMC3 gene.

R. Burgeson, A. Christiano, P. Cserhalmi-Friedman, 2001, Biochemical and biophysical research communications.

Response from the American Hair Research Society to "Sunscreen and Frontal Fibrosing Alopecia: A Review".

A. Tosti, A. Christiano, W. Bergfeld, 2020, Journal of the American Academy of Dermatology.

Deposited in DRO : 03 January 2019 Version of attached

H. Abaci, Zongyou Guo, A. Coffman, 2019 .

Validation of Case Identification for Alopecia Areata Using International Classification of Diseases Coding

A. Christiano, A. Mostaghimi, L. Bordone, 2020, International journal of trichology.

Progenitor Cells in Development and Regeneration of the Hair Follicle The Dermal Papilla : An Instructive Niche for Epithelial Stem and

F. Watt, A. Christiano, R. Whitson, 2014 .

277 An open label pilot clinical trial of the JAK inhibitor tofacitinib for alopecia areata

A. Christiano, J. Cerise, R. Clynes, 2016 .

JAK-STAT Signaling Jump Starts the Hair Cycle.

A. Christiano, S. Harel, E. Wang, 2016, The Journal of investigative dermatology.

Human equivalent of the mouse Nude/SCID phenotype: long-term evaluation of immunologic reconstitution after bone marrow transplantation.

A. Masci, C. Pignata, L. Racioppi, 2001, Blood.

Introduction to Selected Epidermal Gene Mutations

A. Christiano, T. Kupper, D. Dubin, 1998 .

Molecular basis of congenital atrichia in humans and mice.

A. Christiano, W. Ahmad, A. Panteleyev, 1999, Cutis.

Challenges and promises in modeling dermatologic disorders with bioengineered skin

N. J. Eungdamrong, S. Sia, Zongyou Guo, 2014, Experimental biology and medicine.

Compound heterozygosity for a nonsense mutation and a splice site mutation in the type VII collagen gene (COL7A1) in recessive dystrophic epidermolysis bullosa.

J. Uitto, J. McGrath, A. Christiano, 1997, Laboratory investigation; a journal of technical methods and pathology.

Cloning of mouse type VII collagen reveals evolutionary conservation of functional protein domains and genomic organization.

J. Uitto, A. Christiano, K. Li, 1996, The Journal of investigative dermatology.

Epithelial Stem Cells Stepping out of Their Niche

A. Christiano, 2004, Cell.

Identification of a novel splice site mutation in the human hairless gene underlying atrichia with papular lesions.

A. Christiano, A. Martinez-Mir, H. Lam, 2005, European journal of dermatology : EJD.

A glycine-to-arginine substitution in the triple-helical domain of type VII collagen in a family with dominant dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, M. Paradisi, 1997, The Journal of investigative dermatology.

Fibrillin immunofluorescence in pseudoxanthoma elasticum.

J. Uitto, A. Christiano, M. Geerts, 1995, Journal of American Academy of Dermatology.

Bone marrow stem cell therapy for recessive dystrophic epidermolysis bullosa.

A. Christiano, M. Cairo, M. Itoh, 2010, Dermatologic clinics.

Maternal germline mosaicism in dominant dystrophic epidermolysis bullosa.

A. Christiano, A. Martinez-Mir, P. Cserhalmi-Friedman, 2001, The Journal of investigative dermatology.

Premature termination codons on both alleles of the type VII collagen gene (COL7A1) in three brothers with recessive dystrophic epidermolysis bullosa.

J. Uitto, A. Christiano, D. Greenspan, 1995, The Journal of clinical investigation.

Mutations in the non-helical linker segment L1-2 of keratin 5 in patients with Weber-Cockayne epidermolysis bullosa simplex.

R. Kucherlapati, E. Fuchs, J. Uitto, 1994, Journal of cell science.

There and back again: hair follicle stem cell dynamics.

A. Christiano, Katherine A. Fantauzzo, 2011, Cell stem cell.

Early‐Onset Heart Failure, Alopecia, and Cutaneous Abnormalities Associated with a Novel Compound Heterozygous Mutation in Desmoplakin

A. Christiano, Teresa M. Lee, M. Garzón, 2015, Pediatric dermatology.

Recurrent missense mutation in the protoporphyrinogen oxidase gene underlies variegate porphyria.

A. Christiano, C. Breitkopf, H. Merk, 1998, American journal of medical genetics.

The genetic basis of “Scarsdale Gourmet Diet” variegate porphyria: a missense mutation in the protoporphyrinogen oxidase gene

A. Christiano, M. Poh-Fitzpatrick, J. Frank, 1998, Archives of Dermatological Research.

Strategy to assess the efficiency of U1 RNA‐hammerhead ribozyme constructs using GFP‐tagged targets

H. Dietz, A. Christiano, P. Cserhalmi-Friedman, 2003, Experimental dermatology.

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma

A. Christiano, R. Clynes, R. Pérez-Lorenzo, 2021, Oncotarget.

Tissue engineering of human hair follicles using a biomimetic developmental approach

H. Abaci, Zongyou Guo, A. Coffman, 2018, Nature Communications.

Differential structural properties and expression patterns suggest functional significance for multiple mouse desmoglein 1 isoforms.

Jouni Uitto, James Wahl, J. Uitto, 2004, Differentiation; research in biological diversity.

cDNA cloning and chromosomal mapping of the mouse type VII collagen gene (Col7a1): evidence for rapid evolutionary divergence of the gene.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Genomics.

A nonsense mutation in the HOXD13 gene underlies synpolydactyly with incomplete penetrance

A. Christiano, M. Wajid, Y. Shimomura, 2011, Journal of Human Genetics.

Autosomal recessive gingival hyperplasia and dental anomalies caused by a 29-base pair duplication in the FAM20A gene

A. Christiano, M. Wajid, Y. Shimomura, 2013, Journal of Human Genetics.

Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

A. Christiano, C. Higgins, James C. Chen, 2013, Proceedings of the National Academy of Sciences.

Challenges and promises in modeling dermatologic disorders with bioengineered skin

N. J. Eungdamrong, S. Sia, Zongyou Guo, 2014, Experimental biology and medicine.

Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle.

H. Bazzi, A. Christiano, M. Mahoney, 2006, Differentiation; research in biological diversity.

Genome-wide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with MCHR 2 Running Head : Copy number variants in alopecia areata

Lynn, M. Nöthen, S. Moebus, 2016 .

Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata.

A. Christiano, R. Vaughan, J. Cerise, 2016, JCI insight.

491 Efficacy of oral tofacitinib in the treatment of lichen planopilaris

A. Christiano, L. Bordone, B. Sallee, 2018 .

075 Clinical investigation of JAK inhibitor Tofacitinib in scarring alopecias

A. Christiano, L. Bordone, 2017 .

STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis

C. Prives, A. Christiano, S. Rokudai, 2018, Proceedings of the National Academy of Sciences.

Hair follicle epithelial stem cells get their sox on.

A. Christiano, 2008, Cell stem cell.

Hairless is a histone H3K9 demethylase

L. Shapiro, A. Christiano, Hyunmi Kim, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Genetic Linkage ofFamilial Granulomatous Inflammatory Arthritis, SkinRash, andUveitis toChromosome 16

A. Christiano, H. Kuivaniemi, G. Tromp, 1996 .

Whole-exome sequencing in a single proband reveals a mutation in the CHST8 gene in autosomal recessive peeling skin syndrome.

A. Christiano, M. Wajid, Y. Shimomura, 2012, Genomics.

CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

H. Abaci, Zongyou Guo, A. Christiano, 2019, Proceedings of the National Academy of Sciences.