D. Lio

C. Caruso, D. Lio, G. Candore, 2002, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

HLA, aging, and longevity: a critical reappraisal.

C. Franceschi, C. Caruso, D. Lio, 2000, Human immunology.

Inflammation, Longevity, and Cardiovascular Diseases

C. Caruso, D. Lio, S. Vasto, 2006, Annals of the New York Academy of Sciences.

PECAM‐1/CD31 in Infarction and Longevity

C. Caruso, D. Lio, G. Caimi, 2007, Annals of the New York Academy of Sciences.

Cytokine Genotyping (TNF and IL-10) in Patients With Celiac Disease and Selective IgA Deficiency

G. Corazza, D. Lio, F. Cataldo, 2003, American Journal of Gastroenterology.

Immunosenescence and anti-immunosenescence therapies: the case of probiotics.

C. Caruso, D. Lio, S. Vasto, 2008, Rejuvenation research.

B cell immunosenescence in the elderly and in centenarians.

C. Caruso, D. Lio, G. Candore, 2008, Rejuvenation research.

In vitro effects of fluticasone propionate on IL-13 production by mitogen-stimulated lymphocytes.

S. Gangemi, C. Caruso, D. Lio, 2002, Mediators of inflammation.

Inflammation, genes and zinc in ageing and age-related diseases

C. Caruso, D. Lio, S. Vasto, 2006, Biogerontology.

Hemostasis and ageing

D. Mari, G. Vitale, D. Lio, 2008, Immunity & Ageing.

Frequency of Polymorphisms of Signal Peptide of TGF‐β1 and −1082G/A SNP at the Promoter Region of Il‐10 Gene in Patients with Carotid Stenosis

C. Caruso, D. Lio, D. Nuzzo, 2006, Annals of the New York Academy of Sciences.

Myocardial infarction marker levels are influenced by prothrombin and tumor necrosis factor-α gene polymorphisms in young patients.

C. Caruso, D. Lio, L. Vaccarino, 2013, Cytokine.

Analysis of polymorphisms Leiden Factor V G1691A and prothrombin G20210A as risk factors for acute myocardial infarction

F. Licastro, A. Branzi, C. Caldarera, 2011, Biogerontology.

CYTOKINE SERUM PROFILE IN A GROUP OF SICILIAN NONAGENARIANS

C. Caruso, D. Lio, L. Vaccarino, 2012, Journal of immunoassay & immunochemistry.

Analysis of candidate genes in celiac disease: a tool to identify life-threatening associated genes?

C. Caruso, D. Lio, D. Nuzzo, 2006, Rejuvenation research.

Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'.

G. Pawelec, C. Caruso, D. Lio, 2002, Trends in immunology.

Genetics of Inflammation in Age‐Related Atherosclerosis

C. Caruso, D. Lio, S. Vasto, 2007, Annals of the New York Academy of Sciences.

On the Road to Accurate Biomarkers for Cardiometabolic Diseases by Integrating Precision and Gender Medicine Approaches

D. Lio, C. Balistreri, L. Scola, 2019, International journal of molecular sciences.

Laboratory parameters in centenarians of Italian ancestry

C. Caruso, D. Lio, M. Malaguarnera, 2008, Experimental Gerontology.

Associations of rs3918242 and rs2285053 MMP-9 and MMP-2 polymorphisms with the risk, severity, and short- and long-term complications of degenerative mitral valve diseases: a 4.8-year prospective cohort study.

D. Lio, G. Ruvolo, C. Balistreri, 2016, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Associations of rs 3918242 and rs 2285053 MMP-9 and MMP-2 polymorphisms with the risk , severity , and short-and long-term complications of degenerative mitral valve diseases : a 4 . 8-year prospective cohort study

D. Lio, G. Ruvolo, C. Balistreri, 2016 .

CCR5 Receptor

C. Caruso, D. Lio, S. Vasto, 2007, Annals of the New York Academy of Sciences.

Major histocompatibility complex regulation of interleukin‐5 production in the mouse

D. Lio, G. Sireci, F. Dieli, 1993, European journal of immunology.

Association between Platelet Glycoprotein Ib‐α and Myocardial Infarction

C. Caruso, D. Lio, G. Caimi, 2006 .

Centenarian offspring: a model for understanding longevity.

C. Caruso, D. Lio, C. Balistreri, 2013, Current vascular pharmacology.

Evaluation of cytokine polymorphisms (TNFα, IFNγ and IL-10) in Down patients with coeliac disease

D. Lio, M. Piccione, F. Cataldo, 2005 .

Does Down's syndrome support the homocysteine theory of atherogenesis? Experience in elderly subjects with trisomy 21.

E. Porcellini, F. Licastro, D. Lio, 2006, Archives of gerontology and geriatrics.

In Vitro Treatment with Interleukin-2 Normalizes Type-1 Cytokine Production by Lymphocytes from Elderly

C. Caruso, D. Lio, C. Balistreri, 2000, Immunopharmacology and immunotoxicology.

The −308G/A polymorphism of TNF‐α influences immunological parameters in old subjects affected by infectious diseases

C. Franceschi, C. Caruso, D. Lio, 2005, International journal of immunogenetics.

Role of environmental and genetic factor interaction in age-related disease development: the gastric cancer paradigm.

C. Caruso, D. Lio, L. Scola, 2008, Rejuvenation research.

Association between HFE mutations and acute myocardial infarction: a study in patients from Northern and Southern Italy.

F. Licastro, A. Branzi, M. Chiappelli, 2003, Blood cells, molecules & diseases.

Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity

C. Franceschi, G. Paolisso, C. Caruso, 2007, Biogerontology.

Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Mechanisms of Ageing and Development.

F. Licastro, M. Chiappelli, C. Caruso, 2006, Annals of the New York Academy of Sciences.

Polymorphisms of Pro-Inflammatory IL-6 and IL-1β Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers

D. Lio, G. Ruvolo, C. Balistreri, 2021, Biomolecules.

G-protein-coupled receptor kinase 5 polymorphism and Takotsubo cardiomyopathy

D. Lio, L. Vaccarino, G. Novo, 2015, Journal of cardiovascular medicine.

Involvement of −308 TNF-α and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients

C. Caruso, D. Lio, M. Malavolta, 2006, Biogerontology.

Single nucleotide polymorphisms (SNPs) of pro-inflammatory/anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype.

A. Tuttolomondo, A. Pinto, V. Arnao, 2012, Cytokine.

Relevance of Gamma Interferon, Tumor Necrosis Factor Alpha, and Interleukin-10 Gene Polymorphisms to Susceptibility to Mediterranean Spotted Fever

C. Caruso, D. Lio, L. Vaccarino, 2009, Clinical and Vaccine Immunology.

Frequency of the HFE gene mutations in five Italian populations.

C. Caruso, D. Lio, A. Amoroso, 2002, Blood cells, molecules & diseases.

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

C. Caruso, D. Lio, G. Candore, 2009, Mechanisms of Ageing and Development.

HLA-DR-linked genes are involved in the control of T lymphocyte blood levels.

C. Caruso, D. Lio, E. Cillari, 1987, Clinical immunology and immunopathology.

OKT4+ and OKT8+ cell subset values and HLA-DR phenotypes.

C. Caruso, D. Lio, A. Salerno, 1985, Journal of clinical & laboratory immunology.

HLA-DR phenotypes and blood levels of T cell subsets.

C. Caruso, D. Lio, E. Cillari, 1984, Tissue antigens.

B cells in the aged: CD27, CD5, and CD40 expression

C. Caruso, D. Lio, M. Malaguarnera, 2003, Mechanisms of Ageing and Development.

Trafficking phenotype and production of granzyme B by double negative B cells (IgG+IgD−CD27−) in the elderly

C. Caruso, D. Lio, S. Buffa, 2014, Experimental Gerontology.

Traf fi cking phenotype and production of granzyme B by double negative B cells ( IgG + IgD − CD 27 − ) in the elderly

C. Caruso, D. Lio, S. Buffa, 2014 .

Regulatory Cytokine Gene Polymorphisms and Risk of Colorectal Carcinoma

C. Caruso, D. Lio, C. Raimondi, 2006, Annals of the New York Academy of Sciences.

Genetic Determined Downregulation of Both Type 1 and Type 2 Cytokine Pathways Might Be Protective against Pancreatic Cancer

C. Caruso, D. Lio, L. Vaccarino, 2009, Annals of the New York Academy of Sciences.

Connexin37 1019 gene polymorphism in myocardial infarction patients and centenarians.

C. Caruso, D. Lio, C. Balistreri, 2007, Atherosclerosis.

Immunological and immunogenetic markers in sporadic Alzheimer’s disease

C. Caruso, D. Lio, G. Candore, 2006, Aging clinical and experimental research.

The Application of Cellular Tests in the Selection of Unrelated Donors for Bone Marrow Transplantation

F. Claas, D. Lio, B. Koene, 1997 .

Susceptibility to Heart Defects in Down Syndrome Is Associated with Single Nucleotide Polymorphisms in HAS 21 Interferon Receptor Cluster and VEGFA Genes

D. Lio, M. Piccione, C. Balistreri, 2020, Genes.

C. Caruso, D. Lio, G. Caimi, 2008, Rejuvenation research.

Role of Proinflammatory Alleles in Longevity and Atherosclerosis

C. Caruso, D. Lio, D. Nuzzo, 2006, Annals of the New York Academy of Sciences.

Opposite Role of Pro‐Inflammatory Alleles in Acute Myocardial Infarction and Longevity

C. Franceschi, G. Paolisso, C. Caruso, 2006, Annals of the New York Academy of Sciences.

Interleukin-5 production by mononuclear cells from aged individuals: implication for autoimmunity

C. Caruso, D. Lio, C. Balistreri, 1999, Mechanisms of Ageing and Development.

Biological Basis of the HLA-B8,DR3-Associated Progression of Acquired Immune Deficiency Syndrome

C. Caruso, D. Lio, G. Candore, 1998, Pathobiology.

A Study of Serum Immunoglobulin Levels in Elderly Persons That Provides New Insights into B Cell Immunosenescence

C. Franceschi, C. Caruso, D. Lio, 2006, Annals of the New York Academy of Sciences.

Memory B cell subpopulations in the aged.

C. Caruso, D. Lio, G. Candore, 2006, Rejuvenation research.

Association between the HFE mutations and longevity: a study in Sardinian population

C. Franceschi, C. Caruso, D. Lio, 2003, Mechanisms of Ageing and Development.

Association between the HLA-DR alleles and longevity: a study in Sardinian population

L. Ferrucci, C. Franceschi, C. Caruso, 2003, Experimental Gerontology.

Analysis of hemochromatosis gene mutations in the Sicilian population: implications for survival and longevity.

C. Caruso, D. Lio, M. Malaguarnera, 2002, Archives of gerontology and geriatrics. Supplement.

Role of TLR4 Polymorphisms in Inflammatory Responses

C. Caruso, D. Lio, C. Balistreri, 2007, Annals of the New York Academy of Sciences.

Cytokine Gene Polymorphisms and Breast Cancer Susceptibility

C. Caruso, D. Lio, C. Raimondi, 2006, Annals of the New York Academy of Sciences.

TNFα, IFNγ and IL-10 gene polymorphisms in a sample of Sicilian patients with coeliac disease

D. Lio, F. Cataldo, L. Scola, 2005 .

Modification of cytokine patterns in subjects bearing the HLA-B8,DR3 phenotype: implications for autoimmunity.

C. Caruso, D. Lio, G. Candore, 1997, Cytokines, cellular & molecular therapy.

Gluten Stimulation Induces an in vitro Expansion of Peripheral Blood Tγδ Cells from HLA-DQ2-Positive Subjects of Families of Patients with Celiac Disease

D. Lio, A. Salerno, F. Cavataio, 1998, Experimental and Clinical Immunogenetics.

HLA and KIR frequencies in Sicilian Centenarians.

C. Caruso, D. Lio, D. Nuzzo, 2010, Rejuvenation research.

ACUTE PHASE RESPONSE IN OLDEST‐OLD INDIVIDUALS AFTER SURGICAL STRESS

C. Caruso, D. Lio, M. Donati, 2006, Journal of the American Geriatrics Society.

Interleukin-12 release by mitogen-stimulated mononuclear cells in the elderly

C. Caruso, D. Lio, G. Candore, 1998, Mechanisms of Ageing and Development.

IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection.

C. Caruso, D. Lio, A. Craxì, 2003, Human immunology.

TGF-β/VEGF-A Genetic Variants Interplay in Genetic Susceptibility to Non-Melanocytic Skin Cancer

D. Lio, G. Accardi, G. Candore, 2022, Genes.

Consumption of wheat foodstuffs not a risk for celiac disease occurrence in burkina faso.

D. Lio, F. Cataldo, S. Musumeci, 2002, Journal of pediatric gastroenterology and nutrition.

IL-1 Superfamily Member (IL-1A, IL-1B and IL-18) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever

D. Lio, L. Scola, C. Colomba, 2022, Biomolecules.

Hypothesis: interleukin-5 production impairment can be a key point in the pathogenesis of the MHC-linked selective IgA deficiency.

C. Caruso, D. Lio, F. Leone, 1998, Autoimmunity.

In vitro impairment of interleukin-5 production in HLA-B8, DR3-positive individuals implications for immunoglobulin A synthesis dysfunction.

C. Caruso, D. Lio, G. Candore, 1995, Human immunology.

A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

D. Lio, G. Ruvolo, S. Sciarretta, 2018, Oxidative medicine and cellular longevity.

Systematic review by meta-analyses on the possible role of TNF-α polymorphisms in association with Alzheimer's disease

C. Franceschi, F. Licastro, C. Caruso, 2009, Brain Research Reviews.

Tumor necrosis factor-α−308A/G polymorphism is associated with age at onset of Alzheimer's disease

G. Annoni, F. Licastro, C. Caruso, 2006, Mechanisms of Ageing and Development.

G. Pawelec, C. Caruso, D. Lio, 1999, Experimental Gerontology.

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence

C. Caruso, D. Lio, G. Candore, 2004, Experimental Gerontology.

Looking for Immunological Risk Genotypes

C. Caruso, D. Lio, G. Candore, 2004, Annals of the New York Academy of Sciences.

Gamma/delta T lymphocytes are affected in the elderly

C. Caruso, D. Lio, G. Candore, 2002, Experimental Gerontology.

Immunological and immunogenetic markers of successful and unsuccessful ageing

C. Caruso, D. Lio, G. Candore, 2002 .

In vitro T cell activation in elderly individuals: failure in CD69 and CD71 expression

C. Caruso, D. Lio, C. Giordano, 1996, Mechanisms of Ageing and Development.

Genetic Control of Immune Response in Carriers of Ancestral Haplotype 8.1

C. Caruso, D. Lio, S. Vasto, 2006, Annals of the New York Academy of Sciences.

Early activation of γδ T lymphocytes in the elderly

C. Caruso, D. Lio, G. Candore, 2001, Mechanisms of Ageing and Development.

Toll-like receptor-4 signaling pathway in aorta aging and diseases: "its double nature".

D. Lio, G. Ruvolo, R. Madonna, 2017, Journal of molecular and cellular cardiology.

Suppression of contact sensitivity by a plastic adherent T-cell, induced in mice infected with Newcastle disease virus (NDV).

D. Lio, F. Dieli, A. Salerno, 1987, British journal of experimental pathology.

Portrait of inflammatory response to ionizing radiation treatment

M. Gilardi, C. Messa, D. Lio, 2015, Journal of Inflammation.

Pathophysiology of age-related diseases

L. Ginaldi, F. Licastro, M. Chiappelli, 2009, Immunity & Ageing.

Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 −1082 promoter SNP and its interaction with TNF-α −308 promoter SNP

C. Franceschi, C. Caruso, D. Lio, 2003, Journal of medical genetics.

Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects

C. Caruso, D. Lio, C. Balistreri, 2008, Ageing Research Reviews.

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease

C. Franceschi, F. Licastro, A. Branzi, 2004, Journal of Medical Genetics.

Characterization of two alternative Interleukin(IL)-10 5'UTR mRNA sequences, induced by lipopolysaccharide (LPS) stimulation of peripheral blood mononuclear cells.

G. Sisino, C. Caruso, D. Lio, 2009, Molecular immunology.

Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Genes and Immunity.

Gender-specific association between −1082 IL-10 promoter polymorphism and longevity

L Scola, D Lio, C. Franceschi, 2002, Genes and Immunity.

Major Histocompatibility Complex Polymorphisms and Ageing

C. Caruso, D. Lio, G. Candore, 2004 .

Role of TLR Polymorphisms in Immunosenescence

C. Caruso, D. Lio, S. Vasto, 2009 .

Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians

L. Ferrucci, C. Franceschi, C. Caruso, 2008, Experimental Gerontology.

Prostate cancer: from the pathophysiologic implications of some genetic risk factors to translation in personalized cancer treatments

D. Lio, G. Carruba, C. Balistreri, 2014, Cancer Gene Therapy.

A genetically determined high setting of TNF-alpha influences immunologic parameters of HLA-B8,DR3 positive subjects: implications for autoimmunity.

C. Caruso, D. Lio, G. Candore, 2001, Human immunology.

High-Intensity Focused Ultrasound- and Radiation Therapy-Induced Immuno-Modulation: Comparison and Potential Opportunities.

G. Russo, M. Gilardi, C. Messa, 2017, Ultrasound in medicine & biology.

Inflammation, ageing and cancer

C. Caruso, D. Lio, G. Carruba, 2009, Mechanisms of Ageing and Development.

Pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype: effect of multiple gene interactions.

C. Caruso, D. Lio, G. Candore, 2002, Autoimmunity reviews.

Impact of CMV and EBV seropositivity on CD8 T lymphocytes in an old population from West-Sicily

G. Pawelec, C. Caruso, D. Lio, 2007, Experimental Gerontology.

Role of TGF-β Pathway Polymorphisms in Sporadic Thoracic Aortic Aneurysm: rs900 TGF-β2 Is a Marker of Differential Gender Susceptibility

D. Lio, L. Vaccarino, G. Ruvolo, 2014, Mediators of inflammation.

Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach

C. Caruso, D. Lio, G. Carruba, 2009, Cancer Immunology, Immunotherapy.

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

D. Lio, C. Balistreri, G. Accardi, 2013, Immunity & Ageing.

Association between the polymorphisms of TLR4 and CD14 genes and Alzheimer's disease.

F. Licastro, M. Chiappelli, C. Caruso, 2008, Current pharmaceutical design.

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

Role of prothrombotic polymorphisms in successful or unsuccessful aging

E. Porcellini, F. Licastro, M. Chiappelli, 2011, Biogerontology.

A pilot study on prostate cancer risk and pro-inflammatory genotypes: pathophysiology and therapeutic implications.

C. Caruso, D. Lio, G. Carruba, 2010, Current pharmaceutical design.

TLR4 Polymorphisms and Ageing: Implications for the Pathophysiology of Age-Related Diseases

C. Caruso, D. Lio, C. Balistreri, 2009, Journal of Clinical Immunology.

C. Franceschi, C. Caruso, D. Lio, 2010, Current pharmaceutical design.

C. Caruso, D. Lio, S. Vasto, 2010, Rejuvenation research.

Pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype: a genetically determined defect of C4 influences immunological parameters of healthy carriers of the haplotype.

M. Cuccia, C. Caruso, D. Lio, 2003, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients

C. Caruso, D. Lio, V. Saba, 2005, Mechanisms of Ageing and Development.

Immunogenetics, Gender, and Longevity

C. Franceschi, C. Caruso, D. Lio, 2006, Annals of the New York Academy of Sciences.

Analysis of HLA-DQA, HLA-DQB frequencies in a group of Sardinian centenarians.

L. Ferrucci, C. Franceschi, C. Caruso, 2006, Rejuvenation research.

Major histocompatibility complex and sporadic Alzheimer's disease: a critical reappraisal

C. Caruso, D. Lio, C. Balistreri, 2004, Experimental Gerontology.

IL-5 enhances in vitro and in vivo antigen-specific IgA production in MHC genetically determined low IL-5 responder mice.

G. Asherson, D. Lio, G. Sireci, 1995, Cellular immunology.

IL-10 and TNF-α polymorphisms and the recovery from HCV infection

C. Caruso, D. Lio, A. Craxì, 2003 .

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

Genetics of longevity. data from the studies on Sicilian centenarians

D. Lio, L. Vaccarino, C. Balistreri, 2012, Immunity & Ageing.

Inflammatory networks in ageing, age-related diseases and longevity

C. Caruso, D. Lio, D. Nuzzo, 2007, Mechanisms of Ageing and Development.

Gluten stimulation induces an in vitro expansion of peripheral blood T gamma delta cells from HLA-DQ2-positive subjects of families of patients with celiac disease.

D. Lio, A. Salerno, F. Cavataio, 1998, Experimental and clinical immunogenetics.

Plasma cytokine profiles in patients with celiac disease and selective IgA deficiency

G. Corazza, D. Lio, F. Cataldo, 2003, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Viral antibody titers are influenced by HLA-DR2 phenotype.

C. Caruso, D. Lio, G. Candore, 1994, Experimental and clinical immunogenetics.

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians

L. Ferrucci, C. Franceschi, C. Caruso, 2004, Aging clinical and experimental research.

The role of IL-1 gene cluster in longevity: a study in Italian population

Claudio Franceschi, Fabiola Olivieri, Domenico Lio, 2003, Mechanisms of Ageing and Development.

Effect of interleukin-6 polymorphisms on human longevity: A systematic review and meta-analysis

C. Franceschi, L. Christiansen, C. Caruso, 2009, Ageing Research Reviews.

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

D. Lio, C. Balistreri, G. Accardi, 2013, Immunity & Ageing.

Acute Myocardial Infarction and Proinflammatory Gene Variants

E. Corder, F. Licastro, C. Caldarera, 2007, Annals of the New York Academy of Sciences.

Biology of longevity: role of the innate immune system.

C. Caruso, D. Lio, D. Nuzzo, 2006, Rejuvenation research.

Role of Toll-like receptor 4 in acute myocardial infarction and longevity.

C. Franceschi, C. Caruso, D. Lio, 2004, JAMA.

MIF rs755622 and IL6 rs1800795 Are Implied in Genetic Susceptibility to End-Stage Renal Disease (ESRD)

D. Lio, L. Vaccarino, C. Balistreri, 2022, Genes.

Pathological Implications of Th1/Th2 Cytokine Genetic Variants in Behçet’s Disease: Data from a Pilot Study in a Sicilian Population

D. Lio, L. Vaccarino, C. Balistreri, 2013, Biochemical Genetics.

CCR5 Proinflammatory Allele in Prostate Cancer Risk

C. Caruso, D. Lio, G. Carruba, 2009, Annals of the New York Academy of Sciences.

CCR 5 Proinflammatory Allele in Prostate Cancer Risk A Pilot Study in Patients and Centenarians from Sicily

C. Caruso, D. Lio, G. Carruba, 2009 .

Association between the Polymorphism of CCR5 and Alzheimer's Disease

F. Licastro, M. Chiappelli, C. Caruso, 2006, Annals of the New York Academy of Sciences.

Polymorphisms of pro-inflammatory genes and Alzheimer's disease risk: A pharmacogenomic approach

F. Licastro, M. Chiappelli, C. Caruso, 2007, Mechanisms of Ageing and Development.

Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of IFN-γ gene in Alzheimer’s disease patients

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Aging clinical and experimental research.

DVWA gene polymorphisms and osteoarthritis

M. Gilardi, C. Messa, D. Lio, 2015, BMC Research Notes.

The molecular basis of the low hemolytic activity of C4 molecules from low‐C4 mice with IgM‐coated erythrocytes

D. Lio, G. Sireci, F. Dieli, 1989, European journal of immunology.

IgG1 antiendomysium and IgG antitissue transglutaminase (anti-tTG) antibodies in coeliac patients with selective IgA deficiency

G. Corazza, D. Lio, F. Cataldo, 2000 .

Inflammation, genes and zinc in Alzheimer's disease

Domenico Lio, Carmela Rita Balistreri, Giuseppina Candore, 2008, Brain Research Reviews.

Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications.

C. Caruso, D. Lio, S. Vasto, 2010, Rejuvenation research.

Systemic immune responses in Alzheimer's disease: in vitro mononuclear cell activation and cytokine production.

M. Barbagallo, C. Caruso, D. Lio, 2010, Journal of Alzheimer's disease : JAD.

Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics.

F. Licastro, M. Chiappelli, C. Caruso, 2010, Journal of Alzheimer's disease : JAD.

Alzheimer's disease and genetics of inflammation: a pharmacogenomic vision.

C. Caruso, D. Lio, S. Vasto, 2007, Pharmacogenomics.

Genetic risk profiles for Alzheimer's disease: Integration of APOE genotype and variants that up-regulate inflammation

E. Corder, E. Porcellini, F. Licastro, 2007, Neurobiology of Aging.

CD14 C (-260)T polymorphism, atherosclerosis, elderly: role of cytokines and metallothioneins.

C. Caruso, D. Lio, V. Saba, 2007, International journal of cardiology.

Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?

D. Lio, G. Ruvolo, C. Balistreri, 2014, AGE.

Can the TLR-4-Mediated Signaling Pathway Be “A Key Inflammatory Promoter for Sporadic TAA”?

D. Lio, G. Ruvolo, C. Balistreri, 2014, Mediators of inflammation.

Identification of three particular morphological phenotypes in sporadic thoracic aortic aneurysm: phenotype III as sporadic thoracic aortic aneurysm biomarker in aged individuals.

C. Caruso, D. Lio, L. Vaccarino, 2014, Rejuvenation research.

Association between platelet endothelial cellular adhesion molecule 1 (PECAM-1/CD31) polymorphisms and acute myocardial infarction: a study in patients from Sicily.

C. Caruso, D. Lio, L. Cavallone, 2004, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Role of TLR4 Receptor Polymorphisms in Boutonneuse Fever

C. Franceschi, C. Caruso, D. Lio, 2005, International journal of immunopathology and pharmacology.

Correlation between clinical response and urinary interleukin levels using different doses and intravesical administration schedules of interferon-alpha-2b combined with epirubicin: a pilot study

D. Lio, S. Salerno, V. Serretta, 2004, Urological Research.

IgG1 antiendomysium and IgG antitissue transglutaminase (anti-tTG) antibodies in coeliac patients with selective IgA deficiency

G. Corazza, D. Lio, F. Cataldo, 2000, Gut.

LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: Biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects

C. Caruso, D. Lio, C. Balistreri, 2011, Mechanisms of Ageing and Development.

Evidences of +896 A/G TLR4 Polymorphism as an Indicative of Prevalence of Complications in T2DM Patients

R. Testa, A. Bonfigli, M. Boemi, 2014, Mediators of inflammation.

Association between the interleukin-1β polymorphisms and Alzheimer's disease: A systematic review and meta-analysis

Antonella Plaia, Claudio Franceschi, Francesco Lescai, 2008, Brain Research Reviews.

Age‐Related Inflammatory Diseases

F. Licastro, M. Chiappelli, C. Caruso, 2006 .

Genotyping strategy of SMAD-3 rs3825977 gene variant for a differential management of ascending aorta aneurysm in women people: Gender oriented diagnostic tools

D. Lio, G. Ruvolo, C. Balistreri, 2020 .

Prevalence of non organ-specific autoantibodies in healthy centenarians.

C. Caruso, D. Lio, M. Malaguarnera, 2002, Archives of gerontology and geriatrics. Supplement.

Search for Genetic Factors Associated with Susceptibility to Multiple Sclerosis

P. Ragonese, M. D’Amelio, C. Caruso, 2006, Annals of the New York Academy of Sciences.

Lack of correlation between HLA-B35 resistance against herpes labialis and antibody titers to HSV-1.

C. Caruso, D. Lio, G. Gallina, 1989, Oral surgery, oral medicine, and oral pathology.

DVWA gene polymorphisms and osteoarthritis

M. Gilardi, C. Messa, D. Lio, 2015, BMC Research Notes.

Analysis of IL-6, IL-10 and IL-17 genetic polymorphisms as risk factors for sepsis development in burned patients.

D. Lio, L. Vaccarino, L. Scola, 2012, Burns : journal of the International Society for Burn Injuries.

Tumor necrosis factor-a308A/G polymorphism is associated with age at onset of Alzheimer's disease

G. Annoni, F. Licastro, C. Caruso, 2006 .

Role of macrophages in bypassing the inhibitory activity of Newcastle disease virus on the T-suppressor-cell circuit which regulates contact sensitivity to picryl chloride.

D. Lio, F. Dieli, A. Salerno, 1988, Cellular immunology.

Immune-inflammatory responses and oxidative stress in Alzheimer's disease: therapeutic implications.

C. Caruso, D. Lio, D. Nuzzo, 2010, Current pharmaceutical design.

B cells compartment in centenarian offspring and old people.

C. Caruso, D. Lio, S. Vasto, 2010, Current pharmaceutical design.

Risk profiles in type 2 diabetes (metabolic syndrome): integration of IL-10 polymorphisms and laboratory parameters to identify vascular damages related complications.

R. Testa, A. Bonfigli, C. Franceschi, 2010, Current pharmaceutical design.

Cytokine profile of breast cell lines after different radiation doses

G. Russo, M. Gilardi, D. Lio, 2017, International journal of radiation biology.

Enumeration of TG lymphocytes in B-chronic lymphocytic leukaemia (B-CLL) by a rapid double-rosetting technique.

D. Lio, A. Salerno, E. Cillari, 1984, Diagnostic immunology.

Age and Cytokine Gene Variants Modulate the Immunogenicity and Protective Effect of SARS-CoV-2 mRNA-Based Vaccination

D. Lio, L. Scola, G. Giammanco, 2023, Vaccines.

Association between C1019T polymorphism of connexin37 and acute myocardial infarction: a study in patients from Sicily.

Marco Caruso, Domenico Lio, Giuseppina Candore, 2005, International journal of cardiology.

C. Caruso, D. Lio, S. Vasto, 2010, Rejuvenation research.

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

C. Caruso, D. Lio, G. Candore, 2009, Mechanisms of Ageing and Development.

G-protein-coupled receptor kinase 5 polymorphism and Takotsubo cardiomyopathy

D. Lio, L. Vaccarino, G. Novo, 2015, Journal of cardiovascular medicine.

B cell immunosenescence in the elderly and in centenarians.

C. Caruso, D. Lio, G. Candore, 2008, Rejuvenation research.

Age- and gender-related values of lymphocyte subsets in subjects from Northern and Southern Italy.

C. Caruso, D. Lio, A. Cossarizza, 2002, Archives of gerontology and geriatrics. Supplement.

Role of the fourth complement component (C4) in the regulation of contact sensitivity. III. In vivo effect of purified C4.

D. Lio, G. Sireci, F. Dieli, 1989, Cellular Immunology.

Induction of contact sensitivity by cell-associated immunocomplexes requires activation of the early complement components.

D. Lio, G. Sireci, F. Dieli, 1992, International journal of experimental pathology.

Relevance of Gamma Interferon, Tumor Necrosis Factor Alpha, and Interleukin-10 Gene Polymorphisms to Susceptibility to Mediterranean Spotted Fever

C. Caruso, D. Lio, L. Vaccarino, 2009, Clinical and Vaccine Immunology.

Tumor necrosis factor-alpha -308A/G polymorphism is associated with age at onset of Alzheimer's disease.

G. Annoni, F. Licastro, C. Caruso, 2006, Mechanisms of ageing and development.

Portrait of inflammatory response to ionizing radiation treatment

M. Gilardi, C. Messa, D. Lio, 2015, Journal of Inflammation.

HLA and KIR frequencies in Sicilian Centenarians.

C. Caruso, D. Lio, D. Nuzzo, 2010, Rejuvenation research.

REGULATORY T CELLS IN FRAIL ELDERLY

C. Caruso, D. Lio, G. Candore, 2007 .

Inﬂammation, Cytokines, Immune Response, Apolipoprotein E, Cholesterol, and Oxidative Stress in Alzheimer Disease: Therapeutic Implications

D. Lio, S. Vasto, G. Candore, 2022 .