D. Golenbock

发表

M. Heneka, D. Golenbock, E. Latz, 2015, Nature Immunology.

Comparative study of lipopolysaccharide-, lipid IVa-, and lipid X-induced tumor necrosis factor production in murine macrophage-like cell lines.

D. Golenbock, R. Proctor, T. Birkland, 1990, Advances in experimental medicine and biology.

Lipopolysaccharide, but not lethal infection, releases tumor necrosis factor in mice.

D. Golenbock, R. Proctor, R. Cornwell, 1990, Advances in experimental medicine and biology.

Ligand-induced conformational changes allosterically activate Toll-like receptor 9

B. Monks, D. Golenbock, E. Latz, 2007, Nature Immunology.

Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs

B. Monks, D. Golenbock, E. Latz, 2003, Scandinavian journal of infectious diseases.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction*

F. Gusovsky, D. Golenbock, W. Christ, 1999, The Journal of Biological Chemistry.

Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

L. Audoly, D. Golenbock, E. Latz, 2007, Nature Immunology.

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

K. Tracey, Huan Yang, Haichao Wang, 2015, The Journal of experimental medicine.

N. Gay, D. Golenbock, K. Fitzgerald, 2006 .

N. Gay, D. Golenbock, K. Fitzgerald, 2006, Proceedings of the National Academy of Sciences of the United States of America.

DOCK8 Functions as an Adaptor that Links TLR–MyD88 Signaling to B Cell Activation

Schneider, Douglas R. McDonald, Ghassan, 2012 .

DOCK 8 functions as an adaptor that links Toll-like receptor – MyD 88 signaling to B cell activation

Douglas R. McDonald, L. Notarangelo, A. Plebani, 2012 .

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Daniel R. Caffrey, B. Monks, D. Golenbock, 2003, The Journal of experimental medicine.

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

B. Monks, D. Golenbock, E. Latz, 2004, Nature Immunology.

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway

D. Golenbock, M. Hardy, T. Espevik, 2009, Nature Immunology.

Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes.

D. Golenbock, C. Raetz, N. Qureshi, 1991, The Journal of biological chemistry.

Outside-in signaling by lipopolysaccharide through a tailless integrin.

M. Arnaout, D. Golenbock, R. Ingalls, 1997, Journal of immunology.

Involvement of CD14 and β2-Integrins in Activating Cells with Soluble and Particulate Lipopolysaccharides and Mannuronic Acid Polymers

D. Golenbock, G. Skjåk-Bræk, T. Espevik, 2000, Infection and Immunity.

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.

F. Ausubel, R. Feinbaum, D. Golenbock, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Xiaoman Li, Mason W Freeman, François Huet, 2004, Physiological genomics.

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

D. Golenbock, O. Rooyackers, Mei-jiao Gong, 2009, Journal of Lipid Research.

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway.

William M. Harley, A. Fox, W. Goldman, 2004, Immunity.

Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal Recognition1

Douglas T. Golenbock, D. Golenbock, E. Latz, 2006, The Journal of Immunology.

Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group

D. Golenbock, D. Brambilla, G. Hillyer, 1995, Clinical and diagnostic laboratory immunology.

Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide.

M. Ferretti, D. Golenbock, I. Dunn, 1998, The Journal of clinical investigation.

The biology of Toll-like receptors.

D. Golenbock, M. Fenton, T. Means, 2000, Cytokine & growth factor reviews.

CD 14-Deficient Murine Macrophages Divergent Response to LPS and Bacteria in Golenbock and

K. Moore, M. Freeman, B. Monks, 2000 .

Identification of CD18 as a novel Taxol binding/signaling protein in murine macrophage membranes

T. Mayadas, D. Golenbock, S. Vogel, 1999 .

Membrane Expression of Soluble Endotoxin-binding Proteins Permits Lipopolysaccharide Signaling in Chinese Hamster Ovary Fibroblasts Independently of CD14*

B. Monks, D. Golenbock, R. Ingalls, 1999, The Journal of Biological Chemistry.

Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.

D. Golenbock, G. Teti, S. Vogel, 1998, Journal of immunology.

CD 11 / CD 18 and CD 14 Share a Common Lipid A Signaling Pathway 1

B. Monks, D. Golenbock, W. Christ, 1998 .

Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction.

D. Golenbock, R. Ingalls, R. Delude, 1998, Journal of immunology.

CD11/CD18 and CD14 share a common lipid A signaling pathway.

B. Monks, D. Golenbock, W. Christ, 1998, Journal of immunology.

Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact

M. Wurfel, R. Thieringer, B. Monks, 1997, The Journal of experimental medicine.

CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxin.

D. Golenbock, R. Ingalls, S. Flaherty, 1997, The Journal of surgical research.

CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide

D. Golenbock, R. Ingalls, 1995, The Journal of experimental medicine.

Novel Engagement of CD14 and Multiple Toll-Like Receptors by Group B Streptococci1

V. Nizet, S. Akira, D. Kasper, 2001, The Journal of Immunology.

The Apoptotic Response to Pneumolysin Is Toll-Like Receptor 4 Dependent and Protects against Pneumococcal Disease

D. Golenbock, M. Wessels, R. Malley, 2005, Infection and Immunity.

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

J. Tschopp, D. Golenbock, E. Lavelle, 2011, The Journal of Biological Chemistry.

The Abi-domain Protein Abx1 Interacts with the CovS Histidine Kinase to Control Virulence Gene Expression in Group B Streptococcus

D. Golenbock, P. Glaser, S. Dramsi, 2013, PLoS pathogens.

MUC1 mucin is a negative regulator of toll-like receptor signaling.

D. Golenbock, H. Kai, S. Gendler, 2008, American journal of respiratory cell and molecular biology.

Toll-Like Receptor 4 Mediates Intracellular Signaling Without TNF-α Release in Response to Cryptococcus neoformans Polysaccharide Capsule1

D. Golenbock, S. Shoham, S. Levitz, 2001, The Journal of Immunology.

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

D. Golenbock, C. Harding, W. Boom, 2009, Cellular immunology.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

G. Superti-Furga, S. Kappe, M. Mota, 2013, Nature Medicine.

Differential Effects of a Toll-Like Receptor Antagonist on Mycobacterium tuberculosis-Induced Macrophage Responses1

J. Keane, D. Golenbock, M. Fenton, 2001, The Journal of Immunology.

LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia.

T. van der Poll, P. Speelman, D. Golenbock, 2004, International immunology.

Innate Immune Responses to Endosymbiotic Wolbachia Bacteria in Brugia malayi and Onchocerca volvulus Are Dependent on TLR2, TLR6, MyD88, and Mal, but Not TLR4, TRIF, or TRAM1

D. Golenbock, J. Kazura, E. Pearlman, 2007, The Journal of Immunology.

TLR9 and the Recognition of Self and Non‐Self Nucleic Acids

D. Golenbock, E. Latz, M. Lamphier, 2006, Annals of the New York Academy of Sciences.

TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.

D. Golenbock, E. Latz, P. Trieu-Cuot, 2008, Cell host & microbe.

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

D. Golenbock, M. Wymann, P. Henneke, 2009, The EMBO journal.

Are Dependent on Onchocerca volvulus and Brugia malayi Bacteria in Wolbachia Innate Immune Responses to Endosymbiotic

D. Golenbock, J. Kazura, E. Pearlman, 2006 .

Trypsin-Sensitive Modulation of Intestinal Epithelial MD-2 as Mechanism of Lipopolysaccharide Tolerance1

G. Gerken, D. Golenbock, D. Podolsky, 2006, The Journal of Immunology.

Recognition of a bacterial adhesin by an integrin: Macrophage CR3 (α M β 2, CD11b CD18 ) binds filamentous hemagglutinin of Bordetella pertussis

D. Relman, S. Falkow, D. Golenbock, 1990, Cell.

Macrophages recognize streptococci through bacterial single‐stranded RNA

D. Golenbock, M. Freudenberg, S. Deshmukh, 2011, EMBO reports.

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

M. Lipsitch, D. Golenbock, M. Wessels, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers*

S. Akira, O. Takeuchi, B. Monks, 2002, The Journal of Biological Chemistry.

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling

F. Re, D. Golenbock, E. Latz, 2003, The Journal of cell biology.

Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

W. Garrett, D. Golenbock, G. Pier, 2013, Proceedings of the National Academy of Sciences.

Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum

Daniel R. Caffrey, D. Golenbock, E. Kurt-Jones, 2022, The Journal of clinical investigation.

Control of the innate immune response by the mevalonate pathway

M. Bergo, D. Kastner, D. Golenbock, 2016, Nature Immunology.

Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis

D. Golenbock, S. Dramsi, G. Mancuso, 2009, The Journal of Immunology.

Lipopolysaccharide Tolerance Epithelial MD2 as Mechanism of Trypsin-Sensitive Modulation of Intestinal

G. Gerken, D. Golenbock, D. Podolsky, 2006 .

RecognitionTLR7 Signaling beyond Endosomal Dendritic Cells Delineates Key Elements of Flavivirus Activation of Plasmacytoid

Ping Liu, D. Golenbock, E. Latz, 2006 .

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis

D. Golenbock, J. Belisle, C. Harding, 2001 .

CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.

R. Thieringer, D. Golenbock, M. Fenton, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Corrigendum: Toll-like receptor 9—dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

L. Audoly, D. Golenbock, E. Latz, 2007, Nature Immunology.

Toll-like receptor 9 – dependent activation by DNA-containing immune complexes is mediated by HMGB 1 and RAGE

L. Audoly, D. Golenbock, E. Latz, 2007 .

Characterization of proinflammatory cytokine production and CD14 expression by murine alveolar macrophage cell lines

D. Golenbock, M. W. Vermeulen, L. K. Ryan, 1997, In Vitro Cellular & Developmental Biology - Animal.

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.

D. Golenbock, Min Hi Park, M. Fitzgerald, 2015, Biochemistry.

Streptococci or Lipopolysaccharide , But Not by Group B monocytogenes Listeria Monocyte Activation by Human Toll-Like Receptor 2 Mediates

D. Golenbock, G. Teti, T. Espevik, 2009 .

Human Toll-Like Receptor 2 Mediates Monocyte Activation by Listeria monocytogenes, But Not by Group B Streptococci or Lipopolysaccharide1

D. Golenbock, G. Teti, T. Espevik, 2000, The Journal of Immunology.

Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.

D. Golenbock, E. Pearlman, Yan Sun, 2005, Investigative ophthalmology & visual science.

Activation of TLR2 and TLR4 by Glycosylphosphatidylinositols Derived from Toxoplasma gondii1

R. Schwarz, D. Golenbock, R. Gazzinelli, 2007, The Journal of Immunology.

Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling.

S. Ram, D. Golenbock, A. Visintin, 2008, Blood.

NLRP3 inflammasome activation drives tau pathology

L. Buée, M. Heneka, D. Golenbock, 2019, Nature.

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

M. Heneka, D. Golenbock, E. Latz, 2020, Alzheimer's Research & Therapy.

Helicobacter pylori Lipopolysaccharide Binds to CD14 and Stimulates Release of Interleukin-8, Epithelial Neutrophil-Activating Peptide 78, and Monocyte Chemotactic Protein 1 by Human Monocytes

D. Golenbock, C. Kelly, S. Keates, 1998, Infection and Immunity.

Innate Immune Responses to Rhodococcus equi 1

D. Golenbock, Shruti Jain, M. Hondalus, 2004 .

Innate Immune Responses to Rhodococcus equi4

D. Golenbock, Shruti Jain, D. Mosser, 2004, The Journal of Immunology.

Innate Immune Responses toRhodococcus equi

D. Golenbock, Shruti Jain, M. Hondalus, 2004 .

Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll‐like receptor (TLR) 8‐dependent

D. Golenbock, P. Lepper, K. Triantafilou, 2005, Cellular microbiology.

Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans

D. Golenbock, S. Levitz, H. Kornfeld, 1994, Infection and immunity.

Chlamydia pneumoniae and Chlamydial Heat Shock Protein 60 Stimulate Proliferation of Human Vascular Smooth Muscle Cells via Toll-Like Receptor 4 and p44/p42 Mitogen-Activated Protein Kinase Activation

D. Golenbock, N. Qureshi, D. Beasley, 2001, Circulation research.

Mitogen-Activated Protein Kinase Activation Human Vascular Smooth Muscle Cells via Toll-Like Receptor 4 and p 44 / p 42 and Chlamydial Heat Shock Protein 60 Stimulate Proliferation of Chlamydia pneumoniae

D. Golenbock, N. Qureshi, D. Beasley, 2001 .

Chlamydia pneumoniaeand Chlamydial Heat Shock Protein 60 Stimulate Proliferation of Human Vascular Smooth Muscle Cells via Toll-Like Receptor 4 and p44/p42 Mitogen-Activated Protein Kinase Activation

D. Golenbock, N. Qureshi, D. Beasley, 2001 .

Innate immune recognition of lipopolysaccharide by endothelial cells

D. Golenbock, P. Henneke, 2002, Critical care medicine.

Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production.

V. Hornung, D. Golenbock, P. Trieu-Cuot, 2016, Cell host & microbe.

Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.

V. Hornung, S. Shaffer, D. Golenbock, 2016, Cell reports.

RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*

B. Monks, D. Golenbock, Shruti Sharma, 2014, The Journal of Biological Chemistry.

NO Is a Macrophage Autonomous Modifier of the Cytokine Response to Streptococcal Single-Stranded RNA

S. Akira, O. Takeuchi, D. Golenbock, 2012, The Journal of Immunology.

Single-Stranded RNA of the Cytokine Response to Streptococcal NO Is a Macrophage Autonomous Modifier

S. Akira, O. Takeuchi, D. Golenbock, 2011 .

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line

D. Schwartz, B. Monks, D. Golenbock, 2001, The Journal of experimental medicine.

Viral Inhibitory Peptide of TLR4, a Peptide Derived from Vaccinia Protein A46, Specifically Inhibits TLR4 by Directly Targeting MyD88 Adaptor-Like and TRIF-Related Adaptor Molecule

A. Bowie, D. Golenbock, A. Halle, 2010, The Journal of Immunology.

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.

V. Tarabykin, F. Heppner, Z. Izsvák, 2020, JCI insight.

Biological Activities of Bacteroides forsythus Lipoproteins and Their Possible Pathological Roles in Periodontal Disease

D. Golenbock, N. Tsuchida, T. Sugaya, 2004, Infection and Immunity.

Lipopolysaccharide-induced stimulation of CD11b/CD18 expression on neutrophils. Evidence of specific receptor-based response and inhibition by lipid A-based antagonists.

D. Golenbock, C. Raetz, W. Lynn, 1991, Journal of immunology.

c-Jun Kinase Is a Critical Signaling Molecule in a Neonatal Model of Group B Streptococcal Sepsis1

D. Golenbock, R. Malley, P. Henneke, 2006, The Journal of Immunology.

A Novel Synthetic Acyclic Lipid A-like Agonist Activates Cells via the Lipopolysaccharide/Toll-like Receptor 4 Signaling Pathway*

F. Gusovsky, D. Golenbock, K. Miyake, 2001, The Journal of Biological Chemistry.

Malaria primes the innate immune response due to interferon-γ induced enhancement of toll-like receptor expression and function

D. Golenbock, R. Gazzinelli, C. Ropert, 2009, Proceedings of the National Academy of Sciences.

Dysregulation of LPS-Induced Toll-Like Receptor 4-MyD88 Complex Formation and IL-1 Receptor-Associated Kinase 1 Activation in Endotoxin-Tolerant Cells1

D. Golenbock, L. Wahl, S. Vogel, 2002, The Journal of Immunology.

Toll-like Receptor (TLR) Signaling in Response toAspergillus fumigatus *

D. Golenbock, S. Levitz, P. Henneke, 2002, The Journal of Biological Chemistry.

TIRAP: how Toll receptors fraternize

D. Golenbock, P. Henneke, 2001, Nature Immunology.

Lipoteichoic Acid-Induced Lung Inflammation Depends on TLR2 and the Concerted Action of TLR4 and the Platelet-Activating Factor Receptor

T. van der Poll, D. Golenbock, S. von Aulock, 2008, The Journal of Immunology.

Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2.

S. Akira, T. van der Poll, K. Takeda, 2004, American journal of respiratory and critical care medicine.

Neutrophil Influx in Response to a Peritoneal Infection with Salmonella Is Delayed in Lipopolysaccharide-Binding Protein or CD14-Deficient Mice1

M. Freeman, D. Golenbock, R. Jack, 2002, The Journal of Immunology.

LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection

M. Freeman, D. Golenbock, R. Jack, 2001, Journal of endotoxin research.

MD‐2 expression is not required for cell surface targeting of Toll‐like receptor 4 (TLR4)

B. Monks, D. Golenbock, A. Visintin, 2006, Journal of leukocyte biology.

Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling1

D. Golenbock, J. Gunawardana, A. Visintin, 2006, The Journal of Immunology.

Pharmacological Inhibition of Endotoxin Responses Is Achieved by Targeting the TLR4 Coreceptor, MD-21

B. Monks, D. Golenbock, E. Latz, 2005, The Journal of Immunology.

Structural requirements of muramylpeptides for induction of Toll-like receptor 2-mediated NF-κB activation in CHO cells

D. Golenbock, H. Takada, A. Yoshimura, 2000, Journal of endotoxin research.

Toll-like Receptor (TLR) 2 Mediates Inflammatory Responses to Oligomerized RrgA Pneumococcal Pilus Type 1 Protein*

C. Benes, D. Golenbock, A. Camilli, 2012, The Journal of Biological Chemistry.

Toll-like receptor-dependent discrimination of streptococci

D. Golenbock, P. Henneke, S. Santos-Sierra, 2006, Journal of endotoxin research.

TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia

O. Levy, D. Golenbock, M. Otto, 2010, PloS one.

Responding to Endotoxin for Toll-Like Receptor 2 Are Capable of Cutting Edge: Cells That Carry A Null Allele

D. Golenbock, M. Rothe, H. Heine, 2013 .

The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated

P. Rice, D. Golenbock, N. Qureshi, 1995, Infection and immunity.

Macrophages: Identification of Murine CD18 Identify Unique Cellular Targets in Murine Use of a Photoactivatable Taxol Analogue to

T. Mayadas, D. Golenbock, S. Vogel, 1999 .

Pulmonary Lipopolysaccharide (LPS)-Binding Protein Inhibits the LPS-Induced Lung Inflammation In Vivo1

T. van der Poll, D. Golenbock, S. Florquin, 2006, The Journal of Immunology.

LPS-Induced Lung Inflammation In Vivo (LPS)-Binding Protein Inhibits the Pulmonary Lipopolysaccharide

D. Golenbock, T. Poll, S. Florquin, 2006 .

Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection.

T. van der Poll, P. Speelman, D. Golenbock, 2005, Clinical immunology.

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.

D. Golenbock, M. Kelliher, F. Chan, 2012, Blood.

MyD88-Dependent Pathways Mediate Resistance to Cryptosporidium parvum Infection in Mice

S. Akira, D. Golenbock, S. Uematsu, 2006, Infection and Immunity.

Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.

D. Golenbock, V. Murthy, D. Beasley, 2005, American journal of physiology. Heart and circulatory physiology.

Induction of Tolerance to Lipopolysaccharide and Mycobacterial Components in Chinese Hamster Ovary/CD14 Cells Is Not Affected by Overexpression of Toll-Like Receptors 2 or 41 2

D. Golenbock, M. Fenton, S. Vogel, 2001, The Journal of Immunology.

Failure of TLR4-driven NF-kappa B activation to stimulate virus replication in models of HIV type 1 activation.

D. Golenbock, Liwu Li, L. Su, 2007, AIDS research and human retroviruses.

Haemophilus influenzae Type b-Outer Membrane Protein Complex Glycoconjugate Vaccine Induces Cytokine Production by Engaging Human Toll-Like Receptor 2 (TLR2) and Requires the Presence of TLR2 for Optimal Immunogenicity1

D. Golenbock, E. Latz, J. Schreiber, 2004, The Journal of Immunology.

Optimal Immunogenicity ( TLR 2 ) and Requires the Presence of TLR 2 Engaging Human Toll-Like Receptor 2 Vaccine Induces Cytokine Production by Membrane Protein Complex Glycoconjugate Type b-Outer Haemophilus influenzae

D. Golenbock, E. Latz, J. Schreiber, 2004 .

Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle.

R. Coimbra, H. Nakaya, D. Golenbock, 2018, Cell host & microbe.

Plasmodium falciparum Infection Causes Proinflammatory Priming of Human TLR Responses1

Trees Jansen, L. Jacobs, M. Netea, 2007, The Journal of Immunology.

MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

D. Golenbock, J. Alvarez‐Leite, R. Gazzinelli, 2007, Microbes and infection.

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

D. Golenbock, E. Latz, T. Means, 2005, The Journal of clinical investigation.

Structure and function of Toll-like receptor proteins.

D. Golenbock, M. Fenton, T. Means, 2000, Life sciences.

Toll-Like Receptor 2 Mediates Persistent Chemokine Release by Chlamydia pneumoniae–Infected Vascular Smooth Muscle Cells

D. Golenbock, D. Beasley, K. Schultz, 2005, Arteriosclerosis, thrombosis, and vascular biology.

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.

B. Monks, D. Golenbock, E. Latz, 2016, Cell reports.

Correction: Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

D. Golenbock, R. Gazzinelli, Dong-hai Wang, 2014, PLoS Pathogens.

Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

D. Golenbock, R. Gazzinelli, Dong-hai Wang, 2014, PLoS pathogens.

of the TLR2/MyD88 Pathway in Microglia by Group B Streptococci through Activation A Mechanism for Neurodegeneration Induced

I. Bechmann, J. Volpe, D. Golenbock, 2006 .

Platelet-Activating Factor Receptor Concerted Action of TLR 4 and the Inflammation Depends on TLR 2 and the Lipoteichoic Acid-Induced Lung

D. Golenbock, C. Draing, M. Leendertse, 2008 .

The Role of Lipopolysaccharide Binding Protein in Resistance to Salmonella Infections in Mice1

D. Golenbock, J. Fierer, D. Heumann, 2002, The Journal of Immunology.

in Mice Infections Salmonella Protein in Resistance to The Role of Lipopolysaccharide Binding

D. Golenbock, J. Fierer, D. Heumann, 2002 .

Inflammation in Mice Ectopically Expressing Human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T Mutant Proteins*

K. Rajewsky, D. Golenbock, Dong-hai Wang, 2013, The Journal of Biological Chemistry.

Importance of extra- and intracellular domains of TLR1 and TLR2 in NF (cid:2) B signaling

F. Re, D. Golenbock, E. Latz, 2003 .

Endotoxin-Tolerant Cells IL-1 Receptor-Associated Kinase 1 Activation Receptor 4-MyD 88 Complex Formation and Dysregulation of LPS-Induced Toll-Like

D. Golenbock, L. Wahl, S. Vogel, 2002 .

Targeting the IL33–NLRP3 axis improves therapy for experimental cerebral malaria

A. Craig, D. Brough, D. Golenbock, 2018, Proceedings of the National Academy of Sciences.

Effects of interleukin-10 on human peripheral blood mononuclear cell responses to Cryptococcus neoformans, Candida albicans, and lipopolysaccharide

D. Golenbock, S. Levitz, S. Nong, 1996, Infection and immunity.

The Shape of Things to Come

D. Golenbock, K. Fitzgerald, 2007, Science.

IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients1

D. Golenbock, S. Frøland, P. Aukrust, 2009, The Journal of Immunology.

Cell activation by Toll-like receptors: role of LBP and CD14

F. Re, D. Golenbock, E. Kurt-Jones, 2004, Journal of endotoxin research.

Adjuvants and their signaling pathways: beyond TLRs

D. Golenbock, E. Lien, 2003, Nature Immunology.

Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.

D. Golenbock, G. Núñez, L. Franchi, 2014, International journal of medical microbiology : IJMM.

Toll-Like Receptors by Group B Streptococci Novel Engagement of CD 14 and Multiple

V. Nizet, S. Akira, O. Takeuchi, 2001 .

Toxins in Group B Streptococcal Sepsis Lipoproteins Are Critical TLR2 Activating

D. Golenbock, S. Dramsi, G. Mancuso, 2008 .

Streptococcus Response to Group B Role of Lipoteichoic Acid in the Phagocyte

S. Akira, D. Kasper, O. Takeuchi, 2005 .

Soluble CD14 promotes LPS activation of CD14-deficient PNH monocytes and endothelial cells.

D. Golenbock, H. Lichenstein, C. Moldow, 1995, The Journal of laboratory and clinical medicine.

Toll-Like Receptors Participate in Macrophage Activation and Intracellular Control of Leishmania ( Viannia ) panamensis (cid:1)

D. Golenbock, N. Saravia, C. Gallego, 2011 .

TRIF Signaling Is Essential for TLR4-Driven IgE Class Switching

S. Akira, R. Geha, J. Manis, 2014, The Journal of Immunology.

IgE Class Switching TRIF Signaling Is Essential for TLR4-Driven

R. Geha, J. Manis, D. Golenbock, 2014 .

Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll Like Receptor 9 Signaling.

D. Golenbock, G. Wong, M. Grant, 2020, Gastroenterology.

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways

D. Golenbock, R. Gazzinelli, D. F. Durso, 2022, Cell reports.

VIPER , a peptide derived from vaccinia protein A 46 , specifically inhibits TLR 4 by directly targetting Mal and TRAM

A. Bowie, D. Golenbock, A. Halle, 2014 .

Targeting MyD88 Adaptor-Like and Specifically Inhibits TLR4 by Directly Derived from Vaccinia Protein A46, Viral Inhibitory Peptide of TLR4, a Peptide

A. Bowie, D. Golenbock, A. Halle, 2010 .

Streptococcal Sepsis Activating Toxins in Group B Lipoproteins Are Critical TLR2

D. Golenbock, G. Mancuso, G. Teti, 2009 .

Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis1

D. Golenbock, S. Dramsi, G. Mancuso, 2008, The Journal of Immunology.

Expression of Functional TLR4 Confers Proinflammatory Responsiveness to Trypanosoma cruzi Glycoinositolphospholipids and Higher Resistance to Infection with T. cruzi1

S. Akira, D. Golenbock, R. Gazzinelli, 2004, The Journal of Immunology.

The Antifungal Drug Amphotericin B Promotes Inflammatory Cytokine Release by a Toll-like Receptor- and CD14-dependent Mechanism*

D. Golenbock, E. Latz, S. Levitz, 2003, Journal of Biological Chemistry.

Lipopolysaccharides from Periodontopathic Bacteria Porphyromonas gingivalis and Capnocytophaga ochracea Are Antagonists for Human Toll-Like Receptor 4

D. Golenbock, A. Yoshimura, Y. Hara, 2002, Infection and Immunity.

CD 14-Deficient Mice Lipopolysaccharide-Binding Protein or Is Delayed in Salmonella Infection with Neutrophil Influx in Response to a Peritoneal

M. Freeman, D. Golenbock, R. Jack, 2002 .

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis1

D. Golenbock, J. Radolf, J. Belisle, 2001, The Journal of Immunology.

Extolling the diversity of bacterial endotoxins

D. Golenbock, M. Fenton, 2001, Nature Immunology.

Mycobacterium tuberculosis Antigen Processing by 19-kDa Lipoprotein of Macrophage Class II MHC Expression and Toll-Like Receptor 2-Dependent Inhibition of Boom and

D. Golenbock, J. Radolf, J. Belisle, 2001 .

The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.

D. Golenbock, M. Fenton, T. Means, 1999, Journal of immunology.

Structure of lipid A and cell activation

P. Rice, D. Golenbock, N. Qureshi, 1999 .

Requirement for Toll-Like Receptors Lipopolysaccharide Differ in Their The CD 14 Ligands Lipoarabinomannan

D. Golenbock, M. Fenton, E. Lien, 1999 .

Response to Group B Streptococcus Role of Lipoteichoic Acid in the Phagocyte

S. Akira, T. Hartung, D. Kasper, 2013 .

Invasive Group B Streptococcal Disease of Differentiation Factor 88 in a Mouse Model Dual Role of TLR2 and Myeloid

S. Akira, D. Golenbock, G. Mancuso, 2004 .

Defective pro-IL-1β responses in macrophages from aged mice

D. Golenbock, K. Fitzgerald, V. Rathinam, 2012, Immunity & Ageing.

Peptidoglycan recognition by the Drosophila Imd pathway

D. Golenbock, N. Silverman, T. Kaneko, 2005, Journal of endotoxin research.

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.

S. Ghosh, D. Golenbock, D. Bartholomeu, 2013, Cell host & microbe.

Requirement of UNC93B1 Reveals a Critical Role for TLR7 in Host Resistance to Primary Infection with Trypanosoma cruzi

D. Golenbock, D. Bartholomeu, R. Gazzinelli, 2011, The Journal of Immunology.

Trypanosoma cruzi Infection with Role for TLR7 in Host Resistance to Primary Requirement of UNC93B1 Reveals a Critical

D. Golenbock, D. Bartholomeu, R. Gazzinelli, 2011 .

UNC93B1 Mediates Host Resistance to Infection with Toxoplasma gondii

B. Beutler, D. Golenbock, R. Gazzinelli, 2010, PLoS pathogens.

Streptococcal Sepsis in a Neonatal Model of Group B c-Jun Kinase Is a Critical Signaling Molecule

D. Golenbock, R. Malley, P. Henneke, 2006 .

Toll‐like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni‐ bacterium acnes

D. Golenbock, L. Romics, A. Dolganiuc, 2005, Journal of leukocyte biology.

Endothelium through Distinct TLRs Proinflammatory Activation in the Bacterial Fimbriae Stimulate

D. Golenbock, A. Visintin, C. Genco, 2008 .

Involves Toll-Like Receptor 4 Activity of the Lung Surfactant Protein-A Cutting Edge: The Immunostimulatory

Mustapha, D. Golenbock, L. Guillot, 2002 .

Structure of the Monophosphoryl Lipid A Moiety Obtained from the Lipopolysaccharide of Chlamydia trachomatis *

P. Rice, D. Golenbock, N. Qureshi, 1997, The Journal of Biological Chemistry.

Surface presentation of LPS is sufficient for initiation of signaling events

B. Monks, D. Golenbock, R. Ingalls, 1999 .

Lipid A Signaling Pathway CD11/CD18 and CD14 Share a Common

B. Monks, D. Golenbock, W. Christ, 1998 .

D. Golenbock, S. Frøland, P. Aukrust, 2008 .

HMGB1 SIGNALS THROUGH TOLL‐LIKE RECEPTOR 2.: 40

K. Tracey, Huan Yang, C. Czura, 2004 .

Protozoan Parasite Glycosylphosphatidylinositol Anchors from a Activation of Toll-Like Receptor-2 by

S. Akira, I. C. Almeida, O. Takeuchi, 2001 .

CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation

Christine E. Becker, K. Moore, K. Rayner, 2013, Nature Immunology.

Defective pro-IL-1beta responses in macrophages from aged mice Defective pro-IL-1beta responses in macrophages from aged mice

D. Golenbock, K. Fitzgerald, V. Rathinam, 2017 .

CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens

D. Golenbock, R. Gazzinelli, J. Lannes-Vieira, 2020, PLoS neglected tropical diseases.

The CD11/CD18 integrins: characterization of three novel LPS signaling receptors.

M. Arnaout, D. Golenbock, R. Ingalls, 1998, Progress in clinical and biological research.

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

D. Golenbock, Iva Hafner-Bratkovič, K. Fitzgerald, 2012, Cellular and Molecular Life Sciences.

A Leptospira interrogans Enzyme with Similarity to Yeast Ste14p That Methylates the 1-Phosphate Group of Lipid A*

D. Golenbock, C. Raetz, R. Cotter, 2005, Journal of Biological Chemistry.

MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR31

D. Golenbock, C. Bryant, Mei-jiao Gong, 2009, The Journal of Immunology.

TLR 3 TLR 2 Signaling and Inhibits Signaling by MyD 88 Adaptor-Like Is Not Essential for Golenbock

D. Golenbock, C. Bryant, Mei-jiao Gong, 2009 .

Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin.

M. Freeman, D. Golenbock, F. Millham, 1993, The Journal of biological chemistry.

A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2

D. Kasper, D. Golenbock, A. Tzianabos, 2006, The Journal of experimental medicine.

Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system.

D. Golenbock, M. Fenton, R. Ingalls, 1996, Journal of immunology.

for disulfide HMGB1– dependent TLR4 signaling

K. Tracey, Huan Yang, Haichao Wang, 2015 .

IKKε and TBK1 are essential components of the IRF3 signaling pathway

T. Maniatis, D. Golenbock, E. Latz, 2003, Nature Immunology.

Human phagocytes have multiple lipid A-binding sites

D. Golenbock, C. Raetz, S. Wright, 1990, Infection and immunity.

Lymphocytic Choriomeningitis Virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses

D. Golenbock, E. Kurt-Jones, R. Finberg, 2008, Journal of Neuroimmunology.

Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil

D. Golenbock, R. Gazzinelli, J. Conn, 2022, The American journal of tropical medicine and hygiene.

Increased Survival in B-Cell-Deficient Mice during Experimental Cerebral Malaria Suggests a Role for Circulating Immune Complexes

S. Ram, D. Golenbock, R. Gazzinelli, 2014, mBio.

Hemolysis-induced lethality involves inflammasome activation by heme

D. Golenbock, M. Bozza, D. Zamboni, 2014, Proceedings of the National Academy of Sciences.

Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II.

R. Maki, D. Golenbock, C. V. van Beveren, 1997, Journal of immunology.

Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.

D. Golenbock, E. Tuomanen, E. Lien, 1999, Journal of immunology.

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.

D. Golenbock, K. Miyake, K. Triantafilou, 2002, Journal of cell science.

Dried Whole Plant Artemisia annua as an Antimalarial Therapy

N. Reich, D. Golenbock, P. Weathers, 2012, PloS one.

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

T. Maniatis, Jacqueline Rosains, D. Golenbock, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Phagocytosis, Innate Immunity, and Host–Pathogen Specificity

D. Golenbock, P. Henneke, 2004, The Journal of experimental medicine.

A guiding map for inflammation

Richard Hotchkiss, Michael T Heneka, Alberto Mantovani, 2017, Nature Immunology.

HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2

K. Tracey, Huan Yang, Haichao Wang, 2006, Shock.

Cutting Edge: The Immunostimulatory Activity of the Lung Surfactant Protein-A Involves Toll-Like Receptor 41

D. Golenbock, L. Guillot, M. Chignard, 2002, The Journal of Immunology.

A Novel Host-Parasite Lipid Cross-talk SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATION*

J. Brouwers, D. Golenbock, E. Latz, 2002 .

Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products*

D. Golenbock, J. Radolf, T. Espevik, 1999, The Journal of Biological Chemistry.

MyD88‐dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi

S. Tzipori, D. Golenbock, H. Mayanja-Kizza, 2011, Parasite immunology.

Type I interferon transcriptional signature in neutrophils and high frequency of low-density granulocytes are associated with tissue damage in malaria

D. Golenbock, R. Gazzinelli, G. Menezes, 2016 .

Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria.

D. Golenbock, R. Gazzinelli, G. Menezes, 2015, Cell reports.

The history of Toll-like receptors — redefining innate immunity

Douglas Golenbock, A. Bowie, D. Golenbock, 2013, Nature Reviews Immunology.

Relationship between Structures and Biological Activities of Mycoplasmal Diacylated Lipopeptides and Their Recognition by Toll-Like Receptors 2 and 6

Douglas T. Golenbock, Ken-ichiro Shibata, Akira Hasebe, 2004, Infection and Immunity.

Human Cytomegalovirus Activates Inflammatory Cytokine Responses via CD14 and Toll-Like Receptor 2

D. Golenbock, E. Latz, E. Kurt-Jones, 2003, Journal of Virology.

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

Douglas T. Golenbock, Larry J. Anderson, Ralph A. Tripp, 2000, Nature Immunology.

Stimulation of Toll-like Receptor 2 by Coxiella burnetii Is Required for Macrophage Production of Pro-inflammatory Cytokines and Resistance to Infection*

I. C. Almeida, J. Samuel, D. Golenbock, 2004, Journal of Biological Chemistry.

Engagement of the Lewis X antigen (CD15) results in monocyte activation.

D. Golenbock, P. Sass, R. Silverstein, 1997, Blood.

Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction* 210

Douglas T. Golenbock, Egil Lien, Terje Espevik, 2002, The Journal of Biological Chemistry.

Characterization of low-density lipoprotein uptake by murine macrophages exposed to Chlamydia pneumoniae.

D. Golenbock, G. Byrne, G. Miranpuri, 1999, Microbes and infection.

Absence of infection with human immunodeficiency virus in Peruvian prostitutes.

D. Golenbock, D. Maki, J. Pfister, 1988, AIDS research and human retroviruses.

MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection

D. Golenbock, E. Kurt-Jones, R. Finberg, 2005, European journal of immunology.

Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.

D. Golenbock, A. Dolganiuc, K. Kodys, 2004, Gastroenterology.

Activation of the NLRP3 inflammasome in microglia: the role of ceramide

M. Heneka, D. Golenbock, E. Latz, 2017, Journal of neurochemistry.

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

R. Malenka, F. Heppner, M. Karayiorgou, 2012, Nature Neuroscience.

NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice

M. Heneka, D. Golenbock, E. Latz, 2012, Nature.

miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN)

Daniel R. Caffrey, F. Rus, D. Golenbock, 2017, The Journal of Biological Chemistry.

Beyond Empiricism: Informing Vaccine Development through Innate Immunity Research

D. Golenbock, S. Levitz, 2012, Cell.

Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity

M. Netea, D. Golenbock, J. Kazura, 2018, The Journal of Immunology.

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways1

M. Freeman, V. Nizet, S. Akira, 2002, The Journal of Immunology.

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

K. Moore, T. Reinheckel, V. Hornung, 2008, Nature Immunology.

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

S. Akira, K. Rock, D. Golenbock, 2007, Nature Medicine.

Recurrent Respiratory Syncytial Virus Infection in a CD14-Deficient Patient

B. Graham, D. Golenbock, L. Bont, 2022, The Journal of infectious diseases.

Genome-Wide Expression Profiling and Mutagenesis Studies Reveal that Lipopolysaccharide Responsiveness Appears To Be Absolutely Dependent on TLR4 and MD-2 Expression and Is Dependent upon Intermolecular Ionic Interactions

D. Golenbock, Mei-jiao Gong, H. Björkbacka, 2011, The Journal of Immunology.

Intermolecular Ionic Interactions MD2 Expression and Is Dependent upon To Be Absolutely Dependent on TLR 4 and Lipopolysaccharide Responsiveness Appears Mutagenesis Studies Reveal that Genome-Wide Expression Profiling and Golenbock

D. Golenbock, Mei-jiao Gong, H. Björkbacka, 2011 .

MD-2 Residues Tyrosine 42, Arginine 69, Aspartic Acid 122, and Leucine 125 Provide Species Specificity for Lipid IVA*

B. Monks, D. Golenbock, J. Meng, 2010, The Journal of Biological Chemistry.

Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction*

B. Monks, D. Golenbock, E. Latz, 2003, Journal of Biological Chemistry.

NLRP3 inflammasome activation drives tau pathology

L. Buée, M. Heneka, D. Golenbock, 2019, Nature.

LPS‐binding proteins and receptors

D. Golenbock, M. Fenton, 1998, Journal of leukocyte biology.

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

M. Heneka, D. Golenbock, E. Latz, 2017, Nature.

Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome

M. Heneka, D. Golenbock, E. Latz, 2019, The EMBO journal.

Epithelial MD-2 as Mechanism of Trypsin-Sensitive Modulation of Intestinal

Douglas T. Golenbock, M. Rünzi, Guido Gerken, 2013 .

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling

D. Schwartz, B. Monks, D. Golenbock, 2001 .

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.

B. Monks, D. Golenbock, H. Heine, 2000, The Journal of clinical investigation.

Heat-Killed Brucella abortus Induces TNF and IL-12p40 by Distinct MyD88-Dependent Pathways: TNF, Unlike IL-12p40 Secretion, Is Toll-Like Receptor 2 Dependent

A. Sher, D. Golenbock, J. Aliberti, 2003, The Journal of Immunology.

Toll-Like Receptor 2 Dependent Pathways : TNF , Unlike IL-12 p 40 Secretion , Is IL-12 p 40 by Distinct MyD 88-Dependent Induces TNF and Brucella abortus Heat

A. Sher, D. Golenbock, J. Aliberti, 2003 .

Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite1

S. Akira, I. C. Almeida, O. Takeuchi, 2001, The Journal of Immunology.

Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis.

D. Golenbock, M. Fenton, T. Means, 1999, Journal of immunology.

Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.

B. Monks, D. Golenbock, M. Rothe, 1999, Journal of immunology.

Lipid X protects mice against fatal Escherichia coli infection

D. Golenbock, W. Craig, C. Raetz, 1988, Infection and immunity.

Lipid X ameliorates pulmonary hypertension and protects sheep from death due to endotoxin

D. Golenbock, C. Raetz, R. Proctor, 1987, Infection and immunity.

Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.

D. Golenbock, E. Latz, H. Wagner, 2010, Immunobiology.

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

V. Tarabykin, F. Heppner, Z. Izsvák, 2019, bioRxiv.

The immunology of Plasmodium vivax malaria

D. Golenbock, R. Gazzinelli, J. Vinetz, 2020, Immunological reviews.

Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi

M. Castro, D. Golenbock, R. Gazzinelli, 2021, PLoS neglected tropical diseases.

Binding of Cryptococcus neoformans to heterologously expressed human complement receptors

D. Golenbock, T. Kozel, S. Levitz, 1997, Infection and immunity.

miR-718 regulates inflammatory cytokine production 1 miR-718 represses pro-inflammatory cytokine production through targeting PTEN

Daniel R. Caffrey, F. Rus, D. Golenbock, 2017 .

Lipopolysaccharide antagonists.

D. Golenbock, W. Lynn, William A Lynn, 1992, Immunology today.

Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2*

Kenshi Yamasaki, Douglas Golenbock, B. Beutler, 2007, Journal of Biological Chemistry.

The Genome of Anopheles darlingi, the main neotropical malaria vector

Francisco Prosdocimi, Jesus Aparecido Ferro, Brenton R. Graveley, 2013, Nucleic acids research.

Title The Genome of Anopheles darlingi , the main neotropical malaria vector Permalink

A. T. Vasconcelos, Rangel C. Souza, B. Walenz, 2013 .

Lipid A binding sites in membranes of macrophage tumor cells.

D. Golenbock, C. Raetz, R. Hampton, 1988, The Journal of biological chemistry.

TNF-Mutants Defective in Endotoxin , But Not Reporter Cell Line and Its Use in Identifying Construction of a Lipopolysaccharide and

D. Golenbock, R. Ingalls, R. Delude, 1998 .

Recognition and plasma clearance of endotoxin by scavenger receptors

M. Krieger, D. Golenbock, M. Penman, 1991, Nature.

Caspase-8 mediates inflammation and disease in rodent malaria

D. Golenbock, R. Gazzinelli, P. A. Assis, 2020, Nature Communications.

Innate sensing of malaria parasites

Douglas T. Golenbock, Katherine A. Fitzgerald, D. Golenbock, 2014, Nature Reviews Immunology.

Neutrophil Paralysis in Plasmodium vivax Malaria

D. Golenbock, R. Gazzinelli, F. Cunha, 2012, PLoS neglected tropical diseases.

A Novel Host-Parasite Lipid Cross-talk

J. Brouwers, D. Golenbock, E. Latz, 2002, The Journal of Biological Chemistry.

A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in Microglia1

I. Bechmann, D. Kasper, J. Volpe, 2006, The Journal of Immunology.

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9

B. Monks, D. Golenbock, E. Latz, 2007, Proceedings of the National Academy of Sciences.

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

K. Moore, M. Freeman, D. Golenbock, 2004, Nature Medicine.

Activation of the NLRP 3 Inflammasome

D. Golenbock, Alessandro Costa, G. Mancuso, 2012 .

Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.

D. Golenbock, H. Heine, E. Lien, 1999, Infectious disease clinics of North America.

Dock8 Functions as an Adaptor That Links Toll-like Receptor– Myd88 Signaling to B Cell Activation Hhs Public Access

Alessandro Plebani, Rima Wakim, Kate Fitzgerald, 2022 .

Gingipains Inactivate a Cell Surface Ligand on Porphyromonas gingivalis That Induces TLR2‐ and TLR4‐Independent Signaling

D. Golenbock, M. Naito, K. Nakayama, 2006, Microbiology and immunology.

Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection

Daniel R. Caffrey, Tomás C. Rodríguez, B. Monks, 2023, bioRxiv.

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

A. Tarakhovsky, Y. Belkaid, D. Golenbock, 2005, Nature Immunology.

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

Douglas T. Golenbock, F. Gusovsky, D. Golenbock, 2011, Proceedings of the National Academy of Sciences.

Dual Role of TLR2 and Myeloid Differentiation Factor 88 in a Mouse Model of Invasive Group B Streptococcal Disease 1

S. Akira, D. Golenbock, G. Mancuso, 2004, The Journal of Immunology.

Cyclic GMP–AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria

S. Shaffer, D. Golenbock, E. Kurt-Jones, 2018, The Journal of Immunology.

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.

D. Golenbock, G. Barber, D. Bartholomeu, 2011, Immunity.

The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling*

D. Golenbock, E. Latz, K. Fitzgerald, 2005, Journal of Biological Chemistry.

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.

S. Parapini, D. Taramelli, T. Egan, 2015, Microbes and infection.

Innate Immune Recognition of Yersinia pseudotuberculosis Type III Secretion

D. Golenbock, R. Isberg, Victoria Auerbuch, 2009, PLoS pathogens.

Lipopolysaccharide Binding Protein Is an Essential Component of the Innate Immune Response to Escherichia coli Peritonitis in Mice

T. van der Poll, D. Golenbock, A. D. de Vos, 2003, Infection and Immunity.

Endotoxin recognition and signal transduction by the TLR4/MD2-complex.

D. Golenbock, K. Fitzgerald, D. C. Rowe, 2004, Microbes and infection.

Mechanisms of TLR9 activation

D. Golenbock, E. Latz, T. Espevik, 2004, Journal of endotoxin research.

Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR

B. Beutler, D. Golenbock, B. Koller, 2019, The Journal of experimental medicine.

MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.

S. Akira, K. Rock, D. Golenbock, 2006, The Journal of clinical investigation.

The CD14+CD16+ Inflammatory Monocyte Subset Displays Increased Mitochondrial Activity and Effector Function During Acute Plasmodium vivax Malaria

D. Golenbock, A. Teixeira-Carvalho, R. Gazzinelli, 2014, PLoS pathogens.

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

T. Maniatis, D. Golenbock, E. Latz, 2003, Nature immunology.

Inflammasomes: too big to miss.

D. Golenbock, E. Latz, A. Stutz, 2009, The Journal of clinical investigation.

Neuroinfl ammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015 .

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients

B. Diamond, S. Ram, D. Golenbock, 2015, mBio.

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress.

K. Moore, M. Koschinsky, D. Golenbock, 2010, Cell metabolism.

NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1

S. Akira, N. Rothwell, Masahiro Yamamoto, 2007, Proceedings of the National Academy of Sciences.

Toll-Like Receptors

D. Golenbock, R. Gazzinelli, K. Fitzgerald, 2009 .

The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses

D. Golenbock, B. Kobe, M. Tate, 2019, The Journal of Immunology.

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling

J. Keane, D. Golenbock, S. Gordon, 2016, Immunity.

MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses*

Douglas T. Golenbock, Paul J. Hertzog, Stephen P. Bottomley, 2009, The Journal of Biological Chemistry.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

S. Akira, N. Gay, Masahiro Yamamoto, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice

Daniel R. Caffrey, M. Heneka, D. Golenbock, 2018, Proceedings of the National Academy of Sciences.

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

K. Moore, K. Rayner, Jiusheng Deng, 2009, Nature Immunology.

Metalloproteinase-dependent TLR 2 ectodomain shedding is involved in soluble toll-like receptor 2 ( sTLR 2 ) production

D. Golenbock, R. Quera, María-Julieta González, 2017 .

Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production

D. Golenbock, M. De la Fuente, R. Quera, 2014, PloS one.

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1

A. Tarakhovsky, Y. Belkaid, D. Golenbock, 2005, Journal of endotoxin research.

Trypanosoma cruzi of TLR9 in Dendritic Cells Infected with Recruitment and Endo-Lysosomal Activation

D. Golenbock, E. Latz, R. Gazzinelli, 2013 .

Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with Trypanosoma cruzi1

D. Golenbock, E. Latz, D. Bartholomeu, 2008, The Journal of Immunology.

Independent Signaling Pathways Differentiation Factor 88-Dependent and Streptococcus Involve Parallel Myeloid Bactericidal Activity Against Group B Cellular Activation , Phagocytosis , and

M. Freeman, V. Nizet, S. Akira, 2002 .

Plasmodium falciparum induces trained innate immunity

M. Netea, D. Golenbock, J. Kazura, 2019 .

Interferon-γ and Granulocyte/Monocyte Colony-stimulating Factor Production by Natural Killer Cells Involves Different Signaling Pathways and the Adaptor Stimulator of Interferon Genes (STING)

J. Cavaillon, F. Souza-Fonseca-Guimaraes, D. Golenbock, 2013, The Journal of Biological Chemistry.

Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

K. Miyazono, Yuuki Imai, H. Takayanagi, 2008, Science.

Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9

B. Monks, D. Golenbock, E. Latz, 2007, Nature Immunology.

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.

D. Golenbock, E. Latz, R. Gazzinelli, 2014, Cell reports.

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

D. Golenbock, 2012 .

The CD 14 + CD 16 + inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria

D. Golenbock, A. Teixeira-Carvalho, M. Tada, 2017 .

Recombinant Ov-ASP-1, a Th1-Biased Protein Adjuvant Derived from the Helminth Onchocerca volvulus, Can Directly Bind and Activate Antigen-Presenting Cells

N. A. Libri, S. Heck, S. Hartmann, 2009, The Journal of Immunology.

Activate Antigen-Presenting Cells , Can Directly Bind and Onchocerca volvulus Protein Adjuvant Derived from the Helminth-ASP-1 , a Th 1-Biased Ov Recombinant

N. A. Libri, S. Heck, S. Hartmann, 2009 .

TLR3‐mediated IFN‐β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor‐like

D. Golenbock, A. Halle, Kamalpreet Nagpal, 2010, European journal of immunology.

Role of Lipoteichoic Acid in the Phagocyte Response to Group B Streptococcus1

Osamu Takeuchi, Douglas T. Golenbock, Thomas Hartung, 2005, The Journal of Immunology.

Of mice and man: TLR11 (finally) finds profilin.

Daniel R. Caffrey, D. Golenbock, F. Lauw, 2005, Trends in immunology.

Toll-Like Receptors Participate in Macrophage Activation and Intracellular Control of Leishmania (Viannia) panamensis

D. Golenbock, N. Saravia, M. Gómez, 2011, Infection and Immunity.

Bacterial Lipopolysaccharide Induces Expression of the Stress Response Genes hop and H411*

B. Monks, D. Golenbock, H. Heine, 1999, The Journal of Biological Chemistry.

UNC93B1 and Nucleic Acid-sensing Toll-like Receptors Mediate Host Resistance to Infection with Leishmania major*

D. Golenbock, R. Gazzinelli, P. Scott, 2013, The Journal of Biological Chemistry.

Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

D. Golenbock, A. Franco, D. Huso, 2009, Infection and Immunity.

Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide

D. Golenbock, W. Lynn, Yannan Liu, 1993, Infection and immunity.

Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages1

K. Moore, M. Freeman, B. Monks, 2000, The Journal of Immunology.

Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent1

D. Golenbock, E. Latz, P. Massari, 2002, The Journal of Immunology.

Dual effects of LPS antibodies on cellular uptake of LPS and LPS-induced proinflammatory functions.

B. Monks, D. Golenbock, L. Wahl, 1997, Journal of immunology.

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages

Douglas T. Golenbock, Ira Tabas, K. Moore, 2006, Proceedings of the National Academy of Sciences.

A Novel Factor H–Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae

M. Unemo, M. Ohnishi, S. Ram, 2012, The Journal of Immunology.

Neisseria gonorrhoeae Immunotherapeutic Molecule against Fc Chimeric - A Novel Factor H

M. Unemo, M. Ohnishi, S. Gulati, 2016 .

MD-2-mediated Ionic Interactions between Lipid A and TLR4 Are Essential for Receptor Activation*

D. Golenbock, E. Lien, J. Meng, 2009, The Journal of Biological Chemistry.

Streptococcal Disease Model of Invasive Group B Differentiation Factor 88 in a Mouse Dual Role of TLR2 and Myeloid

S. Akira, D. Golenbock, G. Teti, 2009 .

Activation of the NLRP3 Inflammasome by Group B Streptococci

D. Golenbock, Alessandro Costa, G. Mancuso, 2012, The Journal of Immunology.

Activation of the NLRP 3 Inflammasome by Group B Streptococci

D. Golenbock, Alessandro Costa, G. Mancuso, 2012 .

The Differential Impact of Disulfide Bonds and N-Linked Glycosylation on the Stability and Function of CD14*

D. Golenbock, C. McKnight, P. Parroche, 2008, Journal of Biological Chemistry.

Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression.

T. Mayadas, D. Golenbock, S. Vogel, 1999, Journal of immunology.

Membrane-Associated Proteins of a Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis Activate the Inflammatory Response through Toll-Like Receptor 2

D. Golenbock, E. Lien, R. Ingalls, 2001, Infection and Immunity.

Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: lessons from a lipopolysaccharide-deficient mutant of Neisseria meningitidis

D. Golenbock, E. Lien, R. Ingalls, 2000, Journal of endotoxin research.

Role of p38 and Early Growth Response Factor 1 in the Macrophage Response to Group B Streptococcus

S. Akira, D. Golenbock, E. Lien, 2009, Infection and Immunity.

Integrative analysis of microRNA and mRNA expression profiles of monocyte‐derived dendritic cells differentiation during experimental cerebral malaria

D. Golenbock, P. A. Assis, E. Cunha-Neto, 2020, Journal of leukocyte biology.

ROLE OF P38 AND EGR-1 IN THE MACROPHAGE RESPONSE TO GROUP B

S. Akira, D. Golenbock, E. Lien, 2009 .

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

D. Lin, Hong Wang, J. Culp, 2017, PloS one.

Elimination and tissue distribution of the monosaccharide lipid A precursor, lipid X, in mice and sheep

D. Golenbock, R. Proctor, J. Will, 1988, Antimicrobial Agents and Chemotherapy.

Bacterial Fimbriae Stimulate Proinflammatory Activation in the Endothelium through Distinct TLRs1

F. C. Gibson, D. Golenbock, A. Visintin, 2008, The Journal of Immunology.

Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis.

D. Relman, S. Falkow, D. Golenbock, 1990, Cell.

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

M. Heneka, D. Golenbock, E. Latz, 2020, Alzheimer's Research & Therapy.

CD14-mediated translocation of nuclear factor-kappa B induced by lipopolysaccharide does not require tyrosine kinase activity.

R. Thieringer, D. Golenbock, M. Fenton, 1994, The Journal of biological chemistry.

Comparative Toll-Like Receptor 4-Mediated Innate Host Defense to Bordetella Infection

Paul B. Mann, D. Golenbock, E. Latz, 2005, Infection and Immunity.

Receptor "cross talk" in innate immunity.

D. Golenbock, E. Latz, 2003, The Journal of clinical investigation.

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling*

Douglas T. Golenbock, Katherine A. Fitzgerald, Mihai G. Netea, 2009, The Journal of Biological Chemistry.

The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2

D. Golenbock, G. Teti, T. Espevik, 2019, PLoS pathogens.

YopJ targets TRAF proteins to inhibit TLR‐mediated NF‐κB, MAPK and IRF3 signal transduction

D. Golenbock, C. Sweet, J. Goguen, 2007, Cellular microbiology.

Commentary 1 Phagocytosis , Innate Immunity , and Host – Pathogen Specificity

D. Golenbock, P. Henneke, 2017 .

The LPS receptor generates inflammatory signals from the cell surface

D. Golenbock, E. Latz, T. Espevik, 2003, Journal of endotoxin research.

Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation

D. Golenbock, G. Szabo, A. McCullough, 2023, Hepatology.

Analysis of the activity to induce toll-like receptor (TLR)2- and TLR4-mediated stimulation of supragingival plaque.

D. Golenbock, A. Yoshimura, Y. Hara, 2008, Journal of periodontology.

3-Hydroxyl-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitor (Statin)-induced 28-kDa Interleukin-1β Interferes with Mature IL-1β Signaling*

D. Golenbock, E. Kurt-Jones, K. Fitzgerald, 2014, The Journal of Biological Chemistry.

Gram-negative endotoxin: a biologically active lipid.

D. Golenbock, S. Galloway, C. Raetz, 1988, Cold Spring Harbor symposia on quantitative biology.

Interferes with Mature IL-1 β ( Statin )-induced 28-kDa Interleukin-1 ( HMG-CoA ) Reductase Inhibitor 3-Hydroxyl-3-methylglutaryl Coenzyme

D. Golenbock, E. Kurt-Jones, K. Fitzgerald, 2014 .

Taxol-Induced Gene Expression as a Major Taxol-Binding Protein and a Role Macrophages : Identification of Murine CD 18 Identify Unique Cellular Targets in Murine Use of a Photoactivatable Taxol Analogue to

T. Mayadas, D. Golenbock, S. Vogel, 1999 .

Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.

C. Thiemermann, T. Hartung, D. Golenbock, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Lymphocytic Choriomeningitis Virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses

D. Golenbock, E. Kurt-Jones, R. Finberg, 2008, Journal of Neuroimmunology.

Systemic inflammation impairs microglial Abeta clearance Systemic inflammation impairs microglial Abeta clearance through NLRP3 inflammasome through NLRP3 inflammasome

M. Heneka, D. Golenbock, E. Latz, 2021 .

Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans

D. Golenbock, S. Levitz, H. Kornfeld, 1994, Infection and immunity.

Hepatitis C Virus Structural Proteins and Activation of Toll-like Receptor 2 and 4

D. Golenbock, H. Blum, T. Baumert, 2005 .

Regulation of TLR9 dependent DNA Immune complex mediated cell activation by High Mobility Group Box Protein 1 (HMGB1) and Receptor for Advanced Glycation End products (RAGE) (128.35)

L. Audoly, D. Golenbock, E. Latz, 2007, Journal of Immunology.

Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes

M. Netea, B. Monks, D. Golenbock, 2011, The Journal of Biological Chemistry.

Introduction: Toll receptors come of age.

D. Golenbock, 2004, Microbes and infection.

Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria.

D. Golenbock, R. Gazzinelli, G. Menezes, 2015, Cell reports.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

G. Superti-Furga, S. Kappe, M. Mota, 2013, Nature Medicine.

TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia

O. Levy, D. Golenbock, M. Otto, 2010, PloS one.

Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

D. Golenbock, A. Franco, C. Sears, 2009, Infection and Immunity.

miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN)

Daniel R. Caffrey, F. Rus, D. Golenbock, 2017, The Journal of Biological Chemistry.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line

D. Schwartz, B. Monks, D. Golenbock, 2001, The Journal of experimental medicine.

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.

S. Parapini, D. Taramelli, T. Egan, 2015, Microbes and infection.

DYSREGULATION OF LPS‐INDUCED TLR4‐MyD88 COMPLEX FORMATION AND IRAK‐1 ACTIVATION IN ENDOTOXIN‐TOLERANT CELLS: 89

D. Golenbock, L. Wahl, S. Vogel, 2004 .

Engagement of the Lewis X antigen (CD15) results in monocyte activation.

D. Golenbock, Siu K. Lo, Philip M. Sass, 1997, Blood.

DOCK8 functions as an adaptor that links Toll-like receptor–MyD88 signaling to B cell activation

Douglas R. McDonald, L. Notarangelo, A. Plebani, 2012, Nature Immunology.

Mechanisms of TLR9 activation

D. Golenbock, E. Latz, T. Espevik, 2004, Journal of endotoxin research.

Dual engagement of the NLRP 3 and AIM 2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria

D. Golenbock, E. Latz, R. Gazzinelli, 2014 .

Lymphocytic Choriomeningitis Virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses

D. Golenbock, E. Kurt-Jones, R. Finberg, 2008, Journal of Neuroimmunology.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Weekly SARS-CoV-2 screening of asymptomatic students and staff to guide and evaluate strategies for safer in-person learning

D. Golenbock, J. Boehm, M. Testa, 2021, medRxiv.

The Abi-domain Protein Abx1 Interacts with the CovS Histidine Kinase to Control Virulence Gene Expression in Group B Streptococcus

D. Golenbock, S. Dramsi, P. Trieu-Cuot, 2013, PLoS pathogens.

Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

D. Golenbock, R. Gazzinelli, K. Fitzgerald, 2014, PLoS pathogens.

DNA-Containing Immunocomplexes Promote Inflammasome DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria CD64high CD32low Inflamma

B. Diamond, S. Ram, D. Golenbock, 2022 .

Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells.

D. Golenbock, R. Gazzinelli, O. Ojelabi, 2024, Cell metabolism.

A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2

D. Kasper, D. Golenbock, A. Tzianabos, 2006, The Journal of experimental medicine.

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

D. Golenbock, Iva Hafner-Bratkovič, K. Fitzgerald, 2012, Cellular and Molecular Life Sciences.