P. Quirke

D. Magee, D. Treanor, M. DeRuiter, 2015, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Loss of expression of oestrogen receptor beta in colon cancer and its association with Dukes' staging.

V. Speirs, P. Quirke, S. Bell, 2005, Oncology reports.

Capecitabine, oxaliplatin, radiotherapy, and excision (CORE) in patients with MRI-defined locally advanced rectal adenocarcinoma: Results of an international multicenter phase II study.

S. Ricci, E. Van Cutsem, C. V. D. van de Velde, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Reporting colorectal cancer

P. Quirke, E. Morris, 2007, Histopathology.

Identifying stage III colorectal cancer patients: the influence of the patient, surgeon, and pathologist.

D. Forman, P. Quirke, N. Maughan, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Surgical management and outcomes of colorectal cancer liver metastases

D. Forman, P. Quirke, G. Poston, 2010, The British journal of surgery.

Kaposi's Sarcoma: A Clinico-Pathologic Overview

C. Bosman, P. Quirke, M. Bisceglia, 1991, Tumori.

Should the Benefit of Adjuvant Chemotherapy in Colon Cancer Be Re-Evaluated?

L. Påhlman, K. Matzel, W. Hohenberger, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Quality of Surgery for Stage III Colon Cancer: Comparison Between England, Germany, and Japan

W. Hohenberger, P. Quirke, K. Sugihara, 2014, Annals of Surgical Oncology.

Morphometric analysis and lymph node yield in laparoscopic complete mesocolic excision performed by supervised trainees

P. Quirke, R. Kennedy, N. West, 2014, The British journal of surgery.

A pictorial description of extralevator abdominoperineal excision for low rectal cancer

P. Quirke, R. Heald, B. Moran, 2012, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Improving the Quality of Colon Cancer Surgery Through a Surgical Education Program

W. Hohenberger, P. Quirke, N. West, 2010, Diseases of the colon and rectum.

Defining the surgical planes on MRI improves surgery for cancer of the low rectum.

Gina Brown, P. Quirke, R. Heald, 2009, The Lancet. Oncology.

Mesocolic plane surgery: an old but forgotten technique?

W. Hohenberger, P. Quirke, N. West, 2009, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Pathology grading of colon cancer surgical resection and its association with survival: a retrospective observational study.

P. Quirke, N. West, P. Finan, 2008, The Lancet. Oncology.

The Modern Abdominoperineal Excision: The Next Challenge After Total Mesorectal Excision

P. Quirke, D. Sebag‐Montefiore, N. Scott, 2005, Annals of surgery.

The Pathologist’s Role in the Assessment of Local Recurrence in Rectal Carcinoma

P. Quirke, N. Scott, 1992 .

Low rectal cancer: a call for a change of approach in abdominoperineal resection.

I. Nagtegaal, C. Marijnen, P. Quirke, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A retrospective observational study of length of stay in hospital after colorectal cancer surgery in England (1998–2010)

P. Quirke, E. Morris, P. Finan, 2016, Medicine.

A Flow Cytometric, Clinical, and Histological Study of Stromal Neoplasms of the Gastrointestinal Tract

P. Quirke, P. N. Cooper, M. Dixon, 1992, The American journal of surgical pathology.

The correlation between endoscopic and histopathological measurements in colorectal polyps

P. Quirke, N. West, E. Tinkler-Hundal, 2015, Histopathology.

Molecular pathology of gastric carcinoma: progress and prospects.

Geraint T. Williams, P. Quirke, P. Wright, 1992, Human pathology.

Comparing mutation calls in fixed tumour samples between the affymetrix OncoScan® array and PCR based next-generation sequencing

P. Quirke, F. Brew, H. Wood, 2017, BMC Medical Genomics.

Can we Save the rectum by watchful waiting or TransAnal microsurgery following (chemo) Radiotherapy versus Total mesorectal excision for early REctal Cancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study

I. Nagtegaal, R. Gray, C. Punt, 2017, BMJ Open.

Pathology is a necessary and informative tool in oncology clinical trials

I. Nagtegaal, P. Quirke, J. V. van Krieken, 2014, The Journal of pathology.

Will Extralevator Abdominoperineal Excision Become the New Gold Standard

P. Quirke, H. Rutten, R. Heald, 2012 .

Addition of panitumumab to irinotecan: Results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC).

T. Hickish, S. Gwyther, P. Quirke, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.

J. Barrett, M. Parmar, R. Stephens, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mesorectal fascia instead of circumferential resection margin in preoperative staging of rectal cancer.

L. Påhlman, I. Nagtegaal, Gina Brown, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

FOxTROT: Randomized phase II study of neoadjuvant chemotherapy (CT) with or without an anti-EGFR monoclonal antibody for locally advanced, operable colon cancer: Planned interim report.

R. Gray, B. Warren, P. Quirke, 2011, Journal of Clinical Oncology.

6003 The correlation between Topoisomerase-I (Topo1) expression and outcome of treatment with capecitabine and irinotecan in advanced colorectal cancer (ACC) patients (pts) treated in the CAIRO study of the Dutch Colorectal Cancer Group (DCCG)

I. Nagtegaal, P. Quirke, M. Koopman, 2009 .

Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone

C. Punt, L. Vermeulen, P. Quirke, 2021, British Journal of Cancer.

Area of Submucosal Invasion and Width of Invasion Predicts Lymph Node Metastasis in pT1 Colorectal Cancers

P. Quirke, I. Botterill, E. Morris, 2015, Diseases of the colon and rectum.

Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial

J. Monson, M. Parmar, R. Stephens, 2009, The Lancet.

The D prefix: toward a reproducible validated alternative end point in rectal cancer.

P. Quirke, R. Glynne-Jones, N. West, 2015, Diseases of the colon and rectum.

Comparison of Magnetic Resonance Imaging and Histopathological Response to Chemoradiotherapy in Locally Advanced Rectal Cancer

S. Ricci, Gina Brown, P. Quirke, 2012, Annals of Surgical Oncology.

Focus on Extralevator Perineal Dissection in Supine Position for Low Rectal Cancer Has Led to Better Quality of Surgery and Oncologic Outcome

I. Nagtegaal, V. Lemmens, C. Velde, 2012, Annals of Surgical Oncology.

Evaluation of the role of pre‐operative magnetic resonance imaging in the management of rectal cancer

P. Quirke, D. Sebag‐Montefiore, D. Blunt, 2001, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Total mesorectal excision and local recurrence: A study of tumour spread in the mesorectum distal to rectal cancer

P. Quirke, N. Scott, M. Dixon, 1995, The British journal of surgery.

Impact of short-course preoperative radiotherapy for rectal cancer on patients' quality of life: data from the Medical Research Council CR07/National Cancer Institute of Canada Clinical Trials Group C016 randomized clinical trial.

R. Stephens, P. Quirke, G. Griffiths, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The English National Low Rectal Cancer Development Programme: key messages and future perspectives

P. Quirke, R. Glynne-Jones, B. Moran, 2014, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

The sigmoid take-off: An anatomical imaging definition of the rectum validated on specimen analysis.

Gina Brown, P. Quirke, B. Moran, 2020, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

The role of the pathologist

P. Quirke, 2005 .

Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial

M. D. James, R. Butler, P. Quirke, 2015, Journal of Clinical Pathology.

Lymphatic vessel distribution in the mucosa and submucosa and potential implications for T1 colorectal tumors.

Pamela F. Jones, D. Treanor, P. Quirke, 2011, Diseases of the colon and rectum.

A uniform residual tumor (R) classification

C. Compton, L. Sobin, I. Nagtegaal, 2009, Cancer.

Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study

A. Darzi, R. Peto, P. Ziprin, 2020, The lancet. Gastroenterology & hepatology.

FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing

R. Butler, P. Quirke, B. Jasani, 2022, Journal of Clinical Pathology.

Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials

P. Quirke, J. Cheadle, G. Middleton, 2016, Annals of oncology : official journal of the European Society for Medical Oncology.

Low abdominoperineal excision rates are associated with high‐workload surgeons and lower tumour height. Is further specialization needed?

D. Forman, P. Quirke, R. Birch, 2011, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Commentary on Demetter et al.

P. Quirke, N. West, G. Hutchins, 2013, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC)

V. Goh, P. Quirke, W. Wong, 2018, Heliyon.

EURECCA consensus conference highlights about colorectal cancer clinical management: the pathologists expert review

I. Nagtegaal, P. Quirke, N. West, 2014, Virchows Archiv.

LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION Histopathological Study of Lateral Tumour Spread and Surgical Excision

P. Quirke, P. Durdey, M. Dixon, 1986, The Lancet.

Colon cancer surgery: pathological quality control is essential for optimal outcomes

P. Quirke, N. West, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Will the Extra Levator Approach for Low Rectal Cancer Become the New Gold Standard

M. DeRuiter, P. Quirke, H. Rutten, 2018 .

The anatomy of the perineal body in relation to abdominoperineal excision for low rectal cancer

D. Magee, D. Treanor, M. DeRuiter, 2016, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Understanding the surgical pitfalls in total mesorectal excision: Investigating the histology of the perirectal fascia and the pelvic autonomic nerves.

D. Magee, D. Treanor, M. DeRuiter, 2015, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

A systematic review of cancer related patient outcomes after anterior resection and abdominoperineal excision for rectal cancer in the total mesorectal excision era.

Gina Brown, P. Quirke, R. Heald, 2011, Surgical oncology.

The validity of the Royal College of Pathologists’ colorectal cancer minimum dataset within a population

D. Forman, P. Quirke, N. Maughan, 2007, British Journal of Cancer.

The Site of the Tumor, Not the Type of Operation, Determines the Worse Prognosis of the Low Rectal Cancer

P. Quirke, J. Garvican, 2006 .

MRI assessment of the bony pelvis may help predict resectability of rectal cancer

P. Quirke, D. Burke, P. Sagar, 2005, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Colorectal cancer reporting: are we failing the patient?

N. Shepherd, P. Quirke, 1997, Journal of clinical pathology.

MRI Predictive Factors for Long-Term Outcomes of Low Rectal Tumours

Gina Brown, P. Quirke, F. Taylor, 2011, Annals of Surgical Oncology.

Relationship Between Baseline Rectal Tumor Length and Magnetic Resonance Tumor Regression Grade Response to Chemoradiotherapy: A Subanalysis of the TRIGGER Feasibility Study

R. Thomas, I. Nagtegaal, D. Tait, 2022, Annals of Surgical Oncology.

Reply to: Does MRI Restaging of Rectal Cancer After Chemoradiotherapy Actually Permit a Change in Surgical Management?

Gina Brown, P. Quirke, B. Moran, 2017, Annals of Surgery.

Ex vivo specimen MRI and pathology confirm a rectosigmoid mesenteric waist at the junction of the mesorectum and mesocolon

P. Quirke, J. Coffey, B. Moran, 2020, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Colorectal cancer

P. Quirke, D. Johnston, I. Taylor, 1994, The Lancet.

KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program

P. Jares, C. Langner, P. Quirke, 2008, Virchows Archiv.

Comparison of molecular and pathologic features of stage II and stage III colon cancer in four large studies conducted for development of the 12-gene colon cancer recurrence score.

D. Kerr, N. Wolmark, R. Gray, 2010 .

Expression of the 17-1A antigen in gastric and gastro-oesophageal junction adenocarcinomas: a potential immunotherapeutic target?

P. Quirke, I. Martin, K. Birbeck, 1999, Journal of clinical pathology.

A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival

P. Broderick, R. Houlston, P. Quirke, 2015, PloS one.

Identification of Helicobacter pylori DNA in the mouths and stomachs of patients with gastritis using PCR.

A. Axon, P. Quirke, D. Tompkins, 1993, Journal of clinical pathology.

DNA aneuploidy in colorectal adenomas.

P. Quirke, C. Bird, M. Dixon, 1986, British Journal of Cancer.

Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy

P. Quirke, P. Loadman, S. Mitra, 2021, The Journal of nutrition.

Cell proliferation in the gastric corpus in Helicobacter pylori associated gastritis and after gastric resection.

A. Axon, P. Quirke, N. Mapstone, 1995, Gut.

Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy.

A. Axon, P. Quirke, N. Mapstone, 1995, Gut.

Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer.

P. Quirke, J. Lindholm, N. West, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Parathyroid hormone‐related peptide: Expression in fetal and neonatal development

P. Quirke, H. Jüppner, A. Malik, 1992, The Journal of pathology.

Severe Symptomatic Hypoglycaemia Due to Quinine Therapy

P. Quirke, P. Wiles, H. Sue-Ling, 1986, Journal of the Royal Society of Medicine.

FOCUS4: MAMS Trial Design in Action. Early Closure of FOCUS4-D (Pan-HER 1, 2 and 3 Inhibitor Versus Placebo) in Advanced Colorectal Cancer (aCRC) Patients, with Tumours Wildtype (WT) for KRAS, NRAS, BRAF and PIK3CA

R. Butler, P. Quirke, H. Wasan, 2017 .

Helicobacter gastritis and intestinal metaplasia in a gastric cancer family

P. Quirke, V. Murday, M. Dixon, 1990, The Lancet.

Prenatal detection of trisomy 21 and 18 from amniotic fluid by quantitative fluorescent polymerase chain reaction.

P. Quirke, B. Nagy, T. Marton, 1998, Journal of medical genetics.

Ploidy, proliferative activity, cluster differentiation antigen expression and clinical remission in highgrade non‐Hodgkin's lymphoma

P. Quirke, C. Bird, J. Child, 1987, Histopathology.

Flow cytometry in the quantitation of DNA aneuploidy and cell proliferation in human disease.

P. Quirke, 1990, Current topics in pathology. Ergebnisse der Pathologie.

Adenoma screening and colorectal cancer.

P. Quirke, A. Pollock, 1991, BMJ.

Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial in the United Kingdom.

J. Monson, D. Jayne, P. Quirke, 2000, Critical reviews in oncology/hematology.

A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS

C. Hurt, P. Quirke, G. Griffiths, 2018, British Journal of Cancer.

An international phase II study of Capecitabine, Oxaliplatin, Radiotherapy and Excision (CORE) in patients with MRI-defined locally advanced rectal adenocarcinoma. Interim results.

S. Ricci, Gina Brown, P. Quirke, 2005 .

Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.

P. Quirke, A. Maraveyas, R. Glynne-Jones, 2014 .

Combined epiregulin (EREG) and amphiregulin (AREG) expression levels as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC).

J. Barrett, P. Quirke, S. Tejpar, 2014 .

Quantitative assessment of tumor cell density in rectal cancer following three different preoperative therapies compared to surgery alone.

H. Grabsch, D. Treanor, I. Nagtegaal, 2010 .

EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum.

Karin Haustermans, Cornelis J H van de Velde, Vincenzo Valentini, 2014, European journal of cancer.

Early mortality from colorectal cancer in England: a retrospective observational study of the factors associated with death in the first year after diagnosis

P. Quirke, U. Macleod, E. Morris, 2013, British Journal of Cancer.

Three-year survival result of CORE (Capecitabine, Oxaliplatin, Radiotherapy and Excision) study after post-operative chemotherapy in patients with locally advanced rectal adenocarcinoma

S. Ricci, Gina Brown, P. Quirke, 2009 .

Colorectal Cancer: Pathology for the radiologist: pathological insights into colorectal cancer

P. Quirke, 2007 .

Edinburgh Research Explorer Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

K. Sirinukunwattana, U. McDermott, Chieh-Hsi Wu, 2020 .

Fluorescent polymerase chain reaction: Part I. A new method allowing genetic diagnosis and DNA fingerprinting of single cells.

P. Quirke, P. Quirke, I. Findlay, 1996, Human reproduction update.

Mutational signature in colorectal cancer caused by genotoxic pks+E. coli

A. Need, M. Meyerson, M. Kayikci, 2020, Nature.

Evaluation of miR 31 3p as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC): Analysis of patients (pts) from the PICCOLO trial.

P. Laurent-Puig, P. Quirke, D. Vernerey, 2015 .

c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma.

P. Quirke, L. Mayne, M. Tavassoli, 1989, British Journal of Cancer.

University of Birmingham Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer

P. Quirke, J. Cheadle, G. Middleton, 2017 .

Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016

Phil Quirke, Kenichi Sugihara, Heather Dawson, 2017, Modern Pathology.

Prognostic and Predictive Value of Tumor Budding in Colorectal Cancer.

R. Gray, P. Quirke, R. Riddell, 2021, Clinical colorectal cancer.

Viewing apoptosis through a ‘TUNEL’

P. Quirke, J. Walker, 2001, The Journal of pathology.

Kinetic and Physical Studies of Cell Death Induced By Chemotherapeutic Agents Or Hyperthermia

P. Quirke, C. Bird, J. Dyson, 1986, Cell and tissue kinetics.

An investigation of different methods of cell cycle analysis by flow cytometry in rectal cancer.

P. Quirke, N. Scott, M. Dixon, 1992, British Journal of Cancer.

Comparison of histopathological and flow cytometric parameters in prediction of prognosis in gastric cancer

P. Quirke, A. Clayden, C. Bird, 1989, The Journal of pathology.

Revised staging: is it really better, or do we not know?

I. Nagtegaal, P. Quirke, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Urgent improvements needed to diagnose and manage Lynch syndrome

R. Houlston, D. Evans, I. Tomlinson, 2017, British Medical Journal.

Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin's lymphoma.

P. Quirke, C. Bird, C. Holgate, 1987, Journal of clinical pathology.

Analysis of an Indian colorectal cancer faecal microbiome collection demonstrates universal colorectal cancer-associated patterns, but closest correlation with other Indian cohorts

P. Quirke, H. Wood, C. Young, 2022, bioRxiv.

Pathologic Processing of the Total Mesorectal Excision

P. Quirke, Susanne W. Carmack, Molly M Campa-Thompson, 2015, Clinics in Colon and Rectal Surgery.

Hodgkin's disease: a flow cytometric study.

P. Quirke, C. Bird, C. O'brien, 1988, Journal of clinical pathology.

Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease

P. Quirke, 2001 .

Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study

P. Sasieni, P. Quirke, B. North, 2022, BMC Cancer.

The risk of colorectal cancer in individuals with mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene: An English population-based study.

P. Quirke, H. Wood, D. Peckham, 2022, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Diagnostic techniques: Rapid genetic diagnosis at 7–9 weeks gestation: diagnosis of sex, single gene defects and DNA fingerprint from coelomic samples

P. Quirke, A. Rutherford, M. Chambers, 1996 .

Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions

D. Wedge, N. López-Bigas, L. Alexandrov, 2022, bioRxiv.

The Grb2 splice variant, Grb3-3, is a negative regulator of RAS activation

P. Quirke, J. Ladbury, C. Seiler, 2022, Communications Biology.

High gastric juice ascorbic acid concentrations in members of a gastric cancer family.

P. Quirke, N. Scott, J. Crabtree, 1993, Carcinogenesis.

Tumour deposits in colorectal cancer: the challenge is continuing

I. Nagtegaal, P. Quirke, 2008 .

Differences in the management of patients requiring an emergency resection for colonic cancer in two European populations

M. Iles, P. Quirke, D. Burke, 2022, BJS open.

Quality-of-life outcomes in older patients with early-stage rectal cancer receiving organ-preserving treatment with hypofractionated short-course radiotherapy followed by transanal endoscopic microsurgery (TREC): non-randomised registry of patients unsuitable for total mesorectal excision

A. Darzi, R. Peto, P. Ziprin, 2022, The Lancet. Healthy longevity.

Comparison of FISH, PRINS, and Conventional and Fluorescent PCR for Single-Cell Sexing: Suitability for Preimplantation Genetic Diagnosis

P. Quirke, A. Rutherford, I. Findlay, 1998, Journal of Assisted Reproduction and Genetics.

Multiple genetic diagnoses from single cells using multiplex PCR: reliability and allele dropout

P. Quirke, I. Findlay, P. Matthews, 1998, Prenatal diagnosis.

Further applications of the polymerase chain reaction

G. Taylor, P. Quirke, 1989, The Journal of pathology.

DNA content and prognosis of non-Hodgkin's lymphoma.

P. Quirke, A. Clayden, C. Bird, 1986, British Journal of Cancer.

Parathyroid hormone related peptide in ovarian carcinoma.

R. Smith, P. Quirke, P. Burton, 1990, Journal of clinical pathology.

Parathyroid hormone-related peptide in the human fetal uro-genital tract

P. Quirke, G. Segre, P. Burton, 1990, Molecular and Cellular Endocrinology.

DNA aneuploidy in ulcerative colitis.

P. Quirke, C. Bird, M. Dixon, 1986, Gut.

Molecular selection of therapy in metastatic colorectal cancer: the FOCUS4 molecularly stratified RCT

R. Butler, J. Graham, P. Quirke, 2022, Efficacy and Mechanism Evaluation.

p53 in colorectal cancer: clinicopathological correlation and prognostic significance

H. Mewes, I. Tetko, P. Quirke, 1991, British Journal of Cancer.

Correspondence Dna Aneuploidy in Ulcerative Colitis

P. Quirke, J. Fozard, 2022 .

Flow cytometry and AgNORs in benign, borderline, and malignant mucinous and serous tumours of the ovary.

P. Quirke, M. Wells, R. Kingston, 1993, International Journal of Gynecological Pathology.

Microsatellite instability in colorectal cancer: improved assessment using fluorescent polymerase chain reaction.

P. Quirke, L. Cawkwell, F. Lewis, 1995, Gastroenterology.

SUMMARY OF PRODUCT CHARACTERISTICS

D. Jayne, P. Quirke, N. Corrigan, 2014 .

Serum and Gastric Luminal Epidermal Growth Factor in Helicobacter Pylori—Associated Gastritis and Peptic Ulcer Disease

A. Axon, P. Quirke, F. Lewis, 1996, Helicobacter.

Cancer’s craving for sugar: an opportunity for clinical exploitation

D. Jayne, P. Quirke, B. Madhok, 2009, Journal of Cancer Research and Clinical Oncology.

Unlocking the archive – gene expression in paraffin‐embedded tissue

K. Hillan, P. Quirke, N. Maughan, 2001, The Journal of pathology.

KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial.

J. Barrett, P. Quirke, F. Elliott, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

P. Quirke, P. Loadman, S. Mitra, 2017, Gut.

Abnormal intestinal permeability. An aetiological factor in chronic psychiatric disorders?

A. Axon, P. Quirke, I. Hamilton, 1987, The British journal of psychiatry : the journal of mental science.

Silver‐stained structures (AgNORs), their dependence on tissue fixation and absence of prognostic relevance in rectal adenocarcinoma

P. Quirke, P. Roberts, M. Dixon, 1989, The Journal of pathology.

Has the new TNM classification for colorectal cancer improved care?

I. Nagtegaal, P. Quirke, H. Schmoll, 2012, Nature Reviews Clinical Oncology.

Flow cytometry in persistent trophoblastic disease.

C. Elston, P. Quirke, M. Wells, 1988, Placenta.

Diagnosis of molar pregnancy and persistent trophoblastic disease by flow cytometry.

C. Elston, P. Quirke, M. Wells, 1987, Journal of clinical pathology.

Flow cytometry of normal, hyperplastic, and malignant human endometrium. A study of ploidy and proliferative indices including comparison with in vitro S-phase labeling.

P. Quirke, M. Wells, J. Thornton, 1989, American journal of obstetrics and gynecology.

What is the role for the circumferential margin in the modern treatment of rectal cancer?

Phil Quirke, I. Nagtegaal, P. Quirke, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Rates of Circumferential Resection Margin Involvement Vary Between Surgeons and Predict Outcomes in Rectal Cancer Surgery

P. Quirke, N. Scott, N. Mapstone, 2002, Annals of surgery.

Preimplantation Genetic Diagnosis Using Fluorescent Polymerase Chain Reaction: Results and Future Developments

P. Quirke, I. Findlay, P. Matthews, 1999, Journal of Assisted Reproduction and Genetics.

Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis.

P. Quirke, R. Lilford, P. Ray, 1995, Human reproduction.

DNA aneuploidy in ulcerative colitis.

P. Quirke, C. Bird, M. Dixon, 1986, Gut.

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

M. Salto‐Tellez, S. Barry, B. Thompson, 2021, Nature Communications.

Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study

이석호, 황수찬, T. Walsh, 2001, British Journal of Cancer.

Cross-platform array comparative genomic hybridization meta-analysis separates hematopoietic and mesenchymal from epithelial tumors

C Caldas, A. V. D. Vaart, H. Grabsch, 2007, Oncogene.

Localised Colon Cancer: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up.

R. Labianca, R. Salazar, P. Laurent-Puig, 2020, Annals of oncology : official journal of the European Society for Medical Oncology.

Leveraging wall-sized high-resolution displays for comparative genomics analyses of copy number variation

Roy A. Ruddle, Darren Treanor, Philip Quirke, 2013, 2013 IEEE Symposium on Biological Data Visualization (BioVis).

High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease–Related Small Bowel Adenocarcinomas

H. Grabsch, K. Maude, I. Nagtegaal, 2010, Clinical Cancer Research.

Pathology of colorectal cancer.

D. Treanor, P. Quirke, Darren Treanor, 2007, Clinical oncology (Royal College of Radiologists (Great Britain)).

Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization

F. Peale, A. Jubb, G. Frantz, 2003, The Journal of pathology.

Modern Management of Colorectal Cancer — A Pathologist's View

P. Quirke, N. Maughan, Philip Quirke, 2003, Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society.

Genomics in Colorectal Cancer: Godsend or Gimmick?

P. Quirke, N. Maughan, 2003, Scandinavian journal of gastroenterology. Supplement.

Pathology--a molecular prognostic approach.

P. Quirke, N. Maughan, 2002, British medical bulletin.

Molecular approaches to colorectal cancer: a review

P. Quirke, F. Sutherland, L. Haine, 1998 .

Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology.

G. Taylor, P. Quirke, S. Bell, 1993, British Journal of Cancer.

In situ validation of an intestinal stem cell signature in colorectal cancer

M. Yaylaoglu, I. Fodor, Nianfeng Ge, 2012, Gut.

Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells

A. Melcher, P. Quirke, G. Cook, 2007, FEBS letters.

Comparison of triplicated (S) and quadruplicated (W) pelvic ileal reservoirs. Studies on manovolumetry, fecal bacteriology, fecal volatile fatty acids, mucosal morphology, and functional results.

P. Quirke, D. Johnston, P. Sagar, 1992, Gastroenterology.

Helicobacter pylori infection and dental care.

A. Axon, P. Quirke, P. Quirke, 1995, Gut.

Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in RAS Wild-Type Metastatic Colorectal Cancer

J. Barrett, J. Pugh, U. Kurkure, 2021, Clinical Cancer Research.

Clinicopathological, genomic and immunological factors in colorectal cancer prognosis

P. Quirke, N. West, E. Morris, 2018, The British journal of surgery.

Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer

Jakob Nikolas Kather, T. Brinker, H. Grabsch, 2021, The Journal of pathology.

EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe.

J. Borrás, J. Coebergh, L. Påhlman, 2013, European journal of cancer.

DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study

P. Quirke, S. Stenning, M. Seymour, 2002, The Lancet.

Diagnosis of complete molar pregnancy by microsatellites in archival material.

G. Taylor, P. Quirke, S. A. Lane, 1993, Journal of clinical pathology.

A retrospective observational study of the relationship between family history and survival from colorectal cancer

R. Houlston, P. Quirke, D. Bishop, 2013, British Journal of Cancer.

Expression of DNA Double-Strand Break Repair Proteins ATM and BRCA1 Predicts Survival in Colorectal Cancer

Phil Quirke, Karen Maude, H. Grabsch, 2006, Clinical Cancer Research.

Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours?

H. Grabsch, D. Kerr, P. Quirke, 2004, Histopathology.

TmaDB: a repository for tissue microarray data

David R. Westhead, Archana Sharma-Oates, Philip Quirke, 2005, BMC Bioinformatics.

Quality of Surgery

P. Quirke, N. West, 2020, Multidisciplinary Treatment of Colorectal Cancer.

What factors determine specimen quality in colon cancer surgery? A cohort study

D. Jayne, P. Quirke, N. Scott, 2020, International Journal of Colorectal Disease.

The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery

W. Hohenberger, P. Quirke, K. Sugihara, 2014, International Journal of Colorectal Disease.

Normal Large Intestine: Anatomy, Specimen Dissection and Histology Relevant to Pathological Practice

P. Quirke, N. West, G. Hutchins, 2012 .

Understanding optimal colonic cancer surgery: comparison of Japanese D3 resection and European complete mesocolic excision with central vascular ligation.

W. Hohenberger, P. Quirke, K. Sugihara, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon.

W. Hohenberger, P. Quirke, N. West, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer.

D. Kerr, S. Shak, F. Baehner, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Role of circumferential margin involvement in the local recurrence of rectal cancer

P. Quirke, N. Scott, I. Martin, 1994, The Lancet.

DNA fingerprinting from single cells

A. Urquhart, P. Quirke, A. Urquhart, 1997, Nature.

Two cases of primary malignant melanoma of the oesophagus.

P. Quirke, J. Isaacs, 1988, Clinical radiology.

Magnetic resonance imaging‐detected lymph nodes close to the mesorectal fascia are rarely a cause of margin involvement after total mesorectal excision

P. Quirke, R. Heald, G. Brown, 2010, The British journal of surgery.

Ischaemic proctitis and adventitial fibromuscular dysplasia of the superior rectal artery

I. Talbot, P. Quirke, I. Talbot, 1984, The British journal of surgery.

Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour

D. Jayne, P. Quirke, N. West, 2015, British Journal of Cancer.

Rapid Trisomy Diagnosis (21, 18, and 13) Using Fluorescent PCR and Short Tandem Repeats: Applications for Prenatal Diagnosis and Preimplantation Genetic Diagnosis

P. Quirke, T. Marton, Z. Papp, 1998, Journal of Assisted Reproduction and Genetics.

Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse

T. Tan, J. Thiery, P. Quirke, 2016, International journal of molecular sciences.

Molecular biology of colorectal neoplasia.

P. Quirke, N. Scott, 1993, Gut.

Biology and genetics of colorectal cancer.

P. Quirke, J. Walker, 2001, European journal of cancer.

Flow cytofluorometric evidence for the differential radioresponsiveness of aneuploid and diploid cervix tumours.

P. Quirke, C. Bird, J. Dyson, 1987, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

K. Sirinukunwattana, C. Hardy, U. McDermott, 2020, Gut.

Image-based consensus molecular subtype classification (imCMS) of colorectal cancer using deep learning

Jens Rittscher, Clare Verrill, Susan Richman, 2019, bioRxiv.

Title: Image-based consensus molecular subtype classification (imCMS) of colorectal cancer using deep learning

Tomlinson, K. Sirinukunwattana, C. Hardy, 2019 .

Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application

T. Brinker, H. Grabsch, J. Chang-Claude, 2022, ESMO open.

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

R. Butler, J. Graham, P. Quirke, 2022, Clinical trials.

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer

M. Salto‐Tellez, U. McDermott, P. Johnston, 2020, Clinical Cancer Research.

Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer.

D. Kerr, R. Gray, P. Quirke, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

IntAct: intra‐operative fluorescence angiography to prevent anastomotic leak in rectal cancer surgery: a randomized controlled trial

V. Goh, D. Miskovic, D. Jayne, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

DNA Methylation, a Biomarker for Colorectal Cancer

A. Jubb, P. Quirke, A. Oates, 2003 .

Multidisciplinary Rectal Cancer Management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2).

J. Borrás, L. Påhlman, K. Haustermans, 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

DCR1 promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

J. Herman, I. Nagtegaal, B. Ylstra, 2016 .

Molecular pathology of colorectal cancer.

P. Quirke, P Quirke, 1997, Annales de pathologie.

Genes mediating programmed cell death: an immunohistochemical study of bcl-2, c-myc and p53 expression in colorectal neoplasia

P. Quirke, N. Scott, A. Jack, 1996, Clinical molecular pathology.

Role of the Oxidative DNA Damage Repair Gene OGG1 in Colorectal Tumorigenesis

V. Moskvina, P. Quirke, P. Propping, 2013 .

Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.

V. Moskvina, P. Quirke, P. Propping, 2013, Journal of the National Cancer Institute.

Comprehensive Mutation Analysis in Colorectal Flat Adenomas

H. Grabsch, D. Lambrechts, M. A. van de Wiel, 2012, PloS one.

Prediction of the response of colorectal cancer to systemic therapy.

P. Quirke, S. Richman, J. Adlard, 2002, The Lancet. Oncology.

p53 in colorectal cancer: clinicopathological correlation and prognostic significance.

P. Quirke, G. Blair, J. Stewart, 1991, British journal of cancer.

Detection of the Epidermal Growth Factor Receptor, Amphiregulin and Epiregulin in Formalin-Fixed Paraffin-Embedded Human Placenta Tissue by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

P. Quirke, M. Clench, L. Cole, 2013, European journal of mass spectrometry.

Intra-tumoral Heterogeneity of KRAS and BRAF Mutation Status in Patients with Advanced Colorectal Cancer (aCRC) and Cost-Effectiveness of Multiple Sample Testing

P. Quirke, S. Richman, C. Daly, 2011, Analytical cellular pathology.

Who to treat with adjuvant therapy in Dukes B/stage II colorectal cancer? The need for high quality pathology

D. Forman, P. Quirke, N. Maughan, 2007, Gut.

Parathyroid hormone-related peptide in normal human fetal development.

K. Nicolaides, P. Quirke, J. Banga, 1990, Journal of molecular endocrinology.

Internal anal sphincter nerves – a macroanatomical and microscopic description of the extrinsic autonomic nerve supply of the internal anal sphincter

P. Quirke, T. Wedel, M. Böttner, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials

J. Barrett, D. Kerr, R. Gray, 2016, The Journal of pathology.

Chapter 5 Promoter CpG island hypermethylation patterns in polypoid and nonpolypoid colorectal adenomas

H. Grabsch, G. Meijer, C. Mulder, 2013 .

Relationship between cell ploidy and glucocorticoid induced death in human lymphoid cell lines.

P. Quirke, C. Bird, J. Dyson, 1984, British Journal of Cancer.

Molecular markers of chemotherapeutic response and toxicity in colorectal cancer

P. Quirke, M. Seymour, M. Braun, 2007, Expert review of anticancer therapy.

Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial

Philip Quirke, Helen Thorpe, D. Jayne, 2005, The Lancet.

Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial

J. Monson, M. Parmar, R. Stephens, 2009, The Lancet.

Long‐term follow‐up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer

D. Jayne, P. Quirke, P. Guillou, 2013, The British journal of surgery.

Multicenter randomized controlled trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme: EnROL.

P. Quirke, S. Dutton, J. Blazeby, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group.

D. Jayne, P. Quirke, P. Guillou, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Flow cytometry: Methodology and applications in pathology

P. Quirke, J. Dyson, 1986, The Journal of pathology.

Lymph nodes, tumor deposits, and TNM: are we getting better?

L. Påhlman, I. Nagtegaal, T. Tot, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Colorectal tumour deposits in the mesorectum and pericolon; a critical review

I. Nagtegaal, P. Quirke, 2007, Histopathology.

Direct multiplex amplification of DNA from a formalin fixed, paraffin wax embedded tissue section

P. Quirke, L. Cawkwell, 2000, Molecular pathology : MP.

Thirty-day postoperative mortality after colorectal cancer surgery in England

Philip Quirke, David Forman, Bernard Rachet, 2011, Gut.

Clinical and molecular characteristics and treatment outcomes of advanced right-colon, left-colon and rectal cancers: data from 1180 patients in a phase III trial of panitumumab with an extended biomarker panel.

J. Barrett, P. Quirke, S. Tejpar, 2020, Annals of oncology : official journal of the European Society for Medical Oncology.

Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations

P. Quirke, J. Worlding, S. Beare, 2017, British Journal of Cancer.

Investigating the poor outcomes of BRAF -mutant advanced colorectal cancer to develop practical treatment strategies

P. Quirke, J. Cheadle, G. Middleton, 2017 .

Histopathological Work-Up of Resection Specimens, Local Excisions and Biopsies in Colorectal Cancer

P. Quirke, N. West, G. Hutchins, 2012, Digestive Diseases.

KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance

P. Quirke, S. Tejpar, J. E. Boers, 2012, Virchows Archiv.

What can the molecular pathologist offer for optimal decision making?

P. Quirke, S. Richman, G. Hutchins, 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

Prognostic value of thymidylate synthase (TS) expression on failure-free survival of fluorouracil-treated metastatic colorectal cancer patients.

M. Parmar, P. Quirke, S. Richman, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair

P. Quirke, O. Kronborg, C. Fenger, 1999, Gut.

Fluorescent PCR: A new technique for PGD of sex and single-gene defects

P. Quirke, A. Rutherford, I. Findlay, 1996, Journal of Assisted Reproduction and Genetics.

KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program

P. Jares, C. Langner, P. Quirke, 2008, Virchows Archiv.

Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial

M. Parmar, R. Butler, J. Graham, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The prediction of local recurrence in rectal adenocarcinoma by histopathological examination

P. Quirke, M. Dixon, P. Quirke, 1988, International Journal of Colorectal Disease.

Detection of somatic mutations in tumors using unaligned clonal sequencing data

Laura A. Crinnion, D. Bonthron, P. Quirke, 2014, Laboratory Investigation.

Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy

C. Huttenhower, J. Barrett, P. Quirke, 2021, Clinical Cancer Research.

The colorectal cancer-associated faecal microbiome of developing countries resembles that of developed countries

C. Huttenhower, R. Seshadri, P. Quirke, 2021, Genome medicine.

Correlation of morphology, immunophenotype, and flow cytometry with remission induction and survival in high grade non‐Hodgkin's lymphoma

I. Ellis, C. Elston, P. Quirke, 1989, The Journal of pathology.

Five‐year follow‐up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer

D G Jayne, D. Jayne, P. Quirke, 2010, The British journal of surgery.

Unacceptable variation in abdominoperineal excision rates for rectal cancer: time to intervene?

D. Forman, P. Quirke, E. Morris, 2008, Gut.

The role of microsatellite instability in gastric carcinoma

P. Quirke, L. Cawkwell, I. Martin, 1998, Gut.

Robotic-assisted surgery compared with laparoscopic resection surgery for rectal cancer: the ROLARR RCT

D. Jayne, P. Quirke, R. Edlin, 2019, Efficacy and Mechanism Evaluation.

Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study

P. Quirke, B. Moran, P. Tekkis, 2016, Annals of surgery.

Acute pouchitis and deficiencies of fuel

P. Quirke, W. Lewis, D. Johnston, 1995, Diseases of the colon and rectum.

Correlation between epithelial cell proliferation and histological grading in gastric mucosa.

A. Axon, P. Moayyedi, P. Quirke, 1999, Journal of clinical pathology.

Cost effectiveness of antenatal screening for cystic fibrosis

T. Sheldon, H. Cuckle, P. Quirke, 1995, BMJ.

A histologic and flow cytometric study of Kaposi's sarcoma

P. Quirke, M. Bisceglia, C. Bosman, 1992, Cancer.

Carcinoma of the ileostomy in a patient with familial adenomatous polyposis

P. Quirke, D. Johnston, J. Primrose, 1988, The British journal of surgery.

Clinical-grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.

Alexander T. Pearson, Philip Quirke, Jakob Nikolas Kather, 2020, Gastroenterology.

New insights into the lymphovascular microanatomy of the colon and the risk of metastases in pT1 colorectal cancer obtained with quantitative methods and three‐dimensional digital reconstruction

Pamela F. Jones, D. Magee, D. Treanor, 2015, Histopathology.

Lynch syndrome screening in colorectal cancer: results of a prospective 2‐year regional programme validating the NICE diagnostics guidance pathway throughout a 5.2‐million population

P. Quirke, N. West, G. Hutchins, 2021, Histopathology.

Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference

M. Morino, R. Beets-Tan, K. Bujko, 2015, Surgical Endoscopy.

Is DNA aneuploidy a good prognostic indicator in patients with advanced colorectal cancer?

P. Quirke, C. Bird, M. Dixon, 1986, British Journal of Cancer.

Prognostic and predictive significance of proliferation in 867 colorectal cancers

I. Fodor, A. Jubb, P. Quirke, 2012, Journal of Clinical Pathology.

Fully transformer-based biomarker prediction from colorectal cancer histology: a large-scale multicentric study

Jakob Nikolas Kather, H. Grabsch, M. Hoffmeister, 2023, ArXiv.

Encrypted federated learning for secure decentralized collaboration in cancer image analysis

Jakob Nikolas Kather, J. Chang-Claude, M. Hoffmeister, 2022, medRxiv.

Swarm learning for decentralized artificial intelligence in cancer histopathology

Jakob Nikolas Kather, T. Brinker, T. Luedde, 2021, Nature Medicine.

Deep Learning for the detection of microsatellite instability from histology images in colorectal cancer: a systematic literature review

Jakob Nikolas Kather, T. Brinker, P. Boor, 2021, ImmunoInformatics.

Weakly supervised annotation‐free cancer detection and prediction of genotype in routine histopathology

Jakob Nikolas Kather, M. Kloor, T. Brinker, 2021, The Journal of pathology.

Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study

Jakob Nikolas Kather, T. Luedde, M. Ebert, 2021, The Lancet. Digital health.

Deep learning detects genetic alterations in cancer histology generated by adversarial networks

Philip Quirke, Jakob Nikolas Kather, Peter Boor, 2021, The Journal of pathology.

Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): a phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum

V. Goh, P. Quirke, W. Wong, 2015, BMC Cancer.

p53 expression and K-ras mutation in colorectal adenomas.

P. Quirke, S. Bell, G. Blair, 1993, Gut.

Storage and analysis of microarray data

David R. Westhead, Phil Quirke, Archana Sharma-Oates, 2005 .

Potential of Molecular Biology in Preoperative Evaluation

P. Quirke, L. Cawkwell, 1997 .

Overexpression of HER2/neu in solid tumours: an immunohistochemical survey

M. Sliwkowski, H. Koeppen, K. Hillan, 2001, Histopathology.

Next Generation intraoperative Lymph node staging for Stratified colon cancer surgery (GLiSten): a multicentre, multinational feasibility study of fluorescence in predicting lymph node-positive disease

D. Jayne, P. Quirke, N. Corrigan, 2016 .

Pathology and Staging

P. Quirke, A. Cairns, K. Birbeck, 2001 .

Multicentre experience with extralevator abdominoperineal excision for low rectal cancer

P. Quirke, N. West, T. Holm, 2010, The British journal of surgery.

Quantitation by flow cytofluorometry of response of tumours of the uterine cervix to radiotherapy.

P. Quirke, C. Bird, J. Dyson, 1985, The British journal of radiology.

Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study

P. D. Peppercorn, P. Quirke, L. Blomqvist, 2006, BMJ : British Medical Journal.

Morphometry of gastric carcinoma: Its association with patient survival, tumour stage, and DNA ploidy

P. Quirke, P. Watt, D. Johnston, 1992, The Journal of pathology.

Accurately Identifying Low‐Allelic Fraction Variants in Single Samples with Next‐Generation Sequencing: Applications in Tumor Subclone Resolution

Philip Quirke, Pamela Rabbitts, Lucy F. Stead, 2013, Human mutation.

Significance of circumferential resection margin involvement after oesophagectomy for cancer

P. Quirke, D. Johnston, M. Dixon, 1993, The British journal of surgery.

PROGNOSIS IN MALIGNANT GLIOMA: A RETROSPECTIVE STUDY OF BIOPSY SPECIMENS BY FLOW CYTOMETRY

P. Quirke, A. Timms, J. McLaughlin, 1989, Neuropathology and Applied Neurobiology.

Confirmation that somatic mutations of beta‐2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial

D. Evans, P. Quirke, S. Richman, 2019, Histopathology.

p53 allelic imbalance in astrocytoma detected using fluorescent PCR of microsatellite repeat polymorphisms

P. Quirke, S. Al-Sarraj, L. R. Bridges, 1995, Neuropathology and applied neurobiology.

Prognostic indicators in centroblastic-centrocytic lymphoma.

C C Bird, J A Child, P. Quirke, 1988, Journal of clinical pathology.

Cluster differentiation antigen expression, proliferative activity and clinical stage in centroblastic centrocytic lymphomas

P. Quirke, C. Bird, J. Child, 1986, The Journal of pathology.

Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique

D. Jayne, P. Quirke, P. Guillou, 2005, The British journal of surgery.

Tumor deposits in colorectal cancer: Refining their definition in the TNM system

I. Nagtegaal, P. Quirke, Y. Ajioka, 2023, Annals of gastroenterological surgery.

EphB2 is a Prognostic Factor in Colorectal Cancer

H. Grabsch, A. Jubb, G. Frantz, 2005, Clinical Cancer Research.

Same day diagnosis of Down's syndrome and sex in single cells using multiplex fluorescent PCR.

P. Quirke, Z. Papp, T. Tóth, 1998, Molecular pathology : MP.

Prenatal detection of trisomy 21 by fluorescent polymerase chain reaction: importance of primer selection and criticism of an earlier report.

P. Quirke, B. Nagy, Z. Papp, 1997, Human genetics.

Video. Fluorescent polymerase chain reaction: Part II. Detailed technique

P. Quirke, I. Findlay, 1996 .

Simultaneous DNA 'fingerprinting', diagnosis of sex and single-gene defect status from single cells.

K. Sullivan, P. Quirke, A. Urquhart, 1995, Human reproduction.

Early gastric cancer: 46 cases treated in one surgical department.

A. Axon, P. Quirke, I. Martin, 1992, Gut.

High grade dysplasia of the gastric mucosa: a marker for gastric carcinoma.

M F Dixon, D Johnston, A. Axon, 1990, Gut.

No Significant Association Between the Fecal Microbiome and the Presence of Irritable Bowel Syndrome-type Symptoms in Patients with Quiescent Inflammatory Bowel Disease.

A. Ford, P. Quirke, D. Gracie, 2018, Inflammatory bowel diseases.

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

J. Herman, I. Nagtegaal, B. Ylstra, 2017, Oncotarget.

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

J. Herman, I. Nagtegaal, B. Ylstra, 2017, Oncotarget.

The effect of a multidisciplinary regional educational programme on the quality of colon cancer resection

A. Bertelsen, P. Quirke, N. West, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Standards and datasets for reporting cancers Dataset for histopathological reporting of colorectal cancer December 2017

N. Shepherd, P. Quirke, M. Loughrey, 2018 .

A quantitative multigene RT-PCR assay for prediction of recurrence in stage II colon cancer: Selection of the genes in four large studies and results of the independent, prospectively designed QUASAR validation study.

D. Kerr, S. Shak, D. Watson, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Staging of colorectal cancer

J. Jass, P. gordon, P. Quirke, 1987, International journal of colorectal disease.

Limitations of Existing Systems of Staging for Rectal Cancer: The Forgotten Margin

P. Quirke, 1997 .

ACP Broadsheet 133: November 1992. Gross examination of the stomach.

P. Quirke, N. Scott, M. Dixon, 1992, Journal of clinical pathology.

Goseki grading in gastric cancer: comparison with existing systems of grading and its reproducibility

P. Quirke, I. Martin, H. Sue-Ling, 1994, Histopathology.

Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival

H. Grabsch, G. Meijer, P. Quirke, 2009, British Journal of Cancer.

Flat adenomas

P. Quirke, A. Cairns, 1999, The British journal of surgery.

Objectives: To assess the variation in risk-adjusted 30-day post-operative mortality for colorectal cancer patients between Hospital Trusts within the English NHS. Design: Retrospective cross sectional population-based study of data extracted from the National Cancer Data Repository Setting: All pro

D. Forman, P. Quirke, P. Finan, 2016 .

An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer

Ivana Holloway, Christopher McCabe, Phil Quirke, 2012, International Journal of Colorectal Disease.

Heterogeneity of colorectal adenocarcinomas evaluated by flow cytometry and histopathology.

P. Quirke, C. Bird, M. Dixon, 1985, British Journal of Cancer.

Challenging diagnostic issues in adenomatous polyps with epithelial misplacement in bowel cancer screening: 5 years’ experience of the Bowel Cancer Screening Programme Expert Board

N. Shepherd, B. Warren, Geraint T. Williams, 2017, Histopathology.

Patients With Low Rectal Cancer Treated by Abdominoperineal Excision Have Worse Tumors and Higher Involved Margin Rates Compared With Patients Treated by Anterior Resection

Philip Quirke, P. Quirke, R. Heald, 2010, Diseases of the colon and rectum.

Carriage of adhesive Escherichia coli after restorative proctocolectomy and pouch anal anastomosis: relation with functional outcome and inflammation.

P. Quirke, A. Lobo, D. Johnston, 1993, Gut.

Blind total gastrectomy for massive bleeding from the stomach

P. Quirke, J. Primrose, D. Johnston, 1986, The British journal of surgery.

Prognostic significance of DNA aneuploidy and cell proliferation in rectal adenocarcinomas

P. Quirke, C. Bird, P. Durdey, 1987, The Journal of pathology.

Training and quality assurance for rectal cancer: 20 years of data is enough.

P. Quirke, 2003, The Lancet. Oncology.

Relevance of magnetic resonance imaging‐detected pelvic sidewall lymph node involvement in rectal cancer

P. Quirke, F. Taylor, L. Blomqvist, 2011, The British journal of surgery.

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial

R. Butler, P. Quirke, H. Wasan, 2018 .

Additional loss of MSH2 and MSH6 expression in sporadic deficient mismatch repair colorectal cancer due to MLH1 promoter hypermethylation

P. Quirke, J. Adlard, N. West, 2019, Journal of Clinical Pathology.

Association between family history and mismatch repair in colorectal cancer

P. Quirke, D. Bishop, S. Bell, 2005, Gut.

Frequency of replication errors in colorectal cancer and their association with family history

P. Quirke, D. Bishop, L. Cawkwell, 1998, Gut.

Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: Can a regional intervention promote national change?

P. Quirke, E. Morris, John C. Taylor, 2020, International journal of cancer.

Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service

P. Quirke, D. Sebag‐Montefiore, E. Morris, 2016, Clinical oncology (Royal College of Radiologists (Great Britain)).

Population-based study of laparoscopic colorectal cancer surgery 2006–2008

D. Forman, D. Jayne, P. Quirke, 2013, The British journal of surgery.

A retrospective observational study examining the characteristics and outcomes of tumours diagnosed within and without of the English NHS Bowel Cancer Screening Programme

P. Quirke, C. Nickerson, J. Patnick, 2012, British Journal of Cancer.

Comparison of treatment and outcome information between a clinical trial and the National Cancer Data Repository

D. Forman, D. Cameron, D. Jayne, 2011, The British journal of surgery.

Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer

Somnath Mukherjee, Phil Quirke, Monica Enescu, 2016, Clinical Cancer Research.

The modern anatomical surgical approach to localised rectal cancer

M. DeRuiter, P. Quirke, T. Wiggers, 2013, EJC supplements : EJC : official journal of EORTC, European Organization for Research and Treatment of Cancer ... [et al.].

The Impact of Short Course Pre-operative Radiotherapy on Patients' Quality of Life: Data from the MRC CR07/NCIC CO16 Randomised Clinical Trial in Patients with Rectal Cancer

R. Stephens, R. Steele, P. Quirke, 2008 .

Extramural depth of tumor invasion at thin-section MR in patients with rectal cancer: results of the MERCURY study.

A. Norman, P. D. Peppercorn, P. Quirke, 2007, Radiology.

Routine short course pre-op radiotherapy or selective post-op chemoradiotherapy for resectable rectal cancer? Preliminary results of the MRC CR07 randomised trial.

J. Monson, R. Stephens, P. Quirke, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Significant Individual Variation Between Pathologists in the Evaluation of Colon Cancer Specimens After Complete Mesocolic Excision

S. Laurberg, P. Quirke, N. West, 2016, Diseases of the colon and rectum.

Quality of surgery: has the time come for colon cancer?

P. Quirke, N. West, 2015, The Lancet. Oncology.

Implementation of complete mesocolic excision at a university hospital in Denmark: An audit of consecutive, prospectively collected colon cancer specimens.

S. Laurberg, P. Quirke, N. West, 2014, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

EnROL: A multicentre randomised trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme

D. Kerr, P. Quirke, S. Love, 2012, BMC Cancer.

Short-term costs of conventional vs laparoscopic assisted surgery in patients with colorectal cancer (MRC CLASICC trial)

P. Quirke, P. Guillou, N. Bosanquet, 2006, British Journal of Cancer.

The future of the TNM staging system in colorectal cancer: time for a debate?

Philip Quirke, Nadine Ectors, Iris Nagtegaal, 2007, The Lancet. Oncology.

The multidisciplinary rectal cancer treatment: main convergences, controversial aspects and investigational areas which support the need for an European Consensus.

L. Påhlman, M. Tonato, J. Tepper, 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Can a Novel MRI Staging System for Low Rectal Cancer Aid Surgical Planning?

P. Quirke, R. Heald, B. Moran, 2011, Diseases of the colon and rectum.

Prognosis and response to therapy in colorectal cancer.

P. Quirke, J. Walker, 2002, European journal of cancer.

Rapid determination of trisomy 18 parental origin using fluorescent PCR and small tandem repeat markers: case reports

P. Quirke, T. Marton, Z. Papp, 1998, Clinical Genetics.

Accuracy of radiological staging in identifying high‐risk colon cancer patients suitable for neoadjuvant chemotherapy: a multicentre experience

R. Gray, B. Warren, P. Quirke, 2012, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment

M. Salto‐Tellez, P. Quirke, E. Domingo, 2020, Molecular oncology.

Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.

J. Barrett, P. Quirke, S. Tejpar, 2016, JAMA oncology.

A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine?

M. Parmar, G. Taylor, R. Butler, 2014, British Journal of Cancer.

Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring

M. Parmar, R. Butler, J. Graham, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Improving the management of early colorectal cancers (eCRC) by using quantitative markers to predict lymph node involvement and thus the need for major resection of pT1 cancers

P. Quirke, S. Hepworth, E. Morris, 2021, Journal of Clinical Pathology.

Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) ‐ Pathology Standards and Datasets

N. Shepherd, P. Quirke, G. Langman, 2017, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial

S. Laurberg, R. Gray, P. Quirke, 2023, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Sensitive, Simultaneous Quantitation of Two Unlabeled DNA Targets Using a Magnetic Nanoparticle–Enzyme Sandwich Assay

Dejian Zhou, P. Quirke, Yue Zhang, 2013, Analytical chemistry.

The Design and Evaluation of Interfaces for Navigating Gigapixel Images in Digital Pathology

Roy A. Ruddle, Rebecca Randell, Darren Treanor, 2016, ACM Trans. Comput. Hum. Interact..

A new class of colorectal cancer gene.

P. Quirke, L. Cawkwell, 1995, Gut.

KRAS and BRAF mutations in Nigerian colorectal cancers.

H. Grabsch, P. Quirke, F. Abdulkareem, 2012, West African journal of medicine.

Characterisation of dysplastic liver nodules using low‐pass DNA sequencing and detection of chromosome arm‐level abnormalities in blood‐derived cell‐free DNA

P. Quirke, P. Johnson, W. Fateen, 2021, The Journal of pathology.

Comparison of labelling by bromodeoxyuridine, MIB-1, and proliferating cell nuclear antigen in gastric mucosal biopsy specimens.

A. Axon, P. Quirke, M. Dixon, 1994, Journal of clinical pathology.

Abnormal Intestinal Permeability

A. Axon, P. Quirke, I. Hamilton, 1987, British Journal of Psychiatry.

The Six Best Abstracts

P. Quirke, S. Breukink, B. Moran, 2018, Colorectal Disease.

Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS).

M. Parmar, P. Quirke, J. Allan, 2006, Journal of Clinical Oncology.

Assessment of microsatellite alterations in young patients with gastric adenocarcinoma

P. Quirke, D. Johnston, L. Cawkwell, 1997, Cancer.

J. Ledermann, P. Quirke, A. Maraveyas, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Circumferential margin involvement after mesorectal excision of rectal cancer with curative intent

P. Quirke, M. Dixon, P. Finan, 1998, Diseases of the colon and rectum.

A comparison of microsatellite instability in early onset gastric carcinomas from relatively low and high incidence European populations

P. Quirke, F. Pardal, L. Cawkwell, 2000, International journal of cancer.

Prognostic significance of microsatellite instability in patients with gastric carcinoma.

P. Quirke, L. Cawkwell, I. Martin, 1997, European journal of cancer.

Examining the potential use and long-term stability of guaiac faecal occult blood test cards for microbial DNA 16S rRNA sequencing

P. Quirke, H. Wood, S. Halloran, 2016, Journal of Clinical Pathology.

Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer

P. Quirke, P. Guillou, D. Jayne, 2007, The British journal of surgery.

Reply to D.J. Sargent et al.

K. Matzel, W. Hohenberger, P. Quirke, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

GEMS–RCPSG: ‘Is Academic Medicine for Me?’ National Conference 2011, 19 November 2011

H. Branigan, D. Webb, H. Grabsch, 2012 .

Toward routine use of 3D histopathology as a research tool.

Darren Treanor, Mike Shires, Philip Quirke, 2012, The American journal of pathology.

Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

Jakob Nikolas Kather, T. Brinker, H. Grabsch, 2023, Cell reports. Medicine.

Colour Normalisation in Digital Histopathology Images

Derek R. Magee, Darren Treanor, Mike Shires, 2009 .

Comparing mutation calls in fixed tumour samples between the affymetrix OncoScan® array and PCR based next-generation sequencing

P. Quirke, F. Brew, H. Wood, 2017, BMC Medical Genomics.

Mutation Detection by Clonal Sequencing of PCR Amplicons and Grouped Read Typing is Applicable to Clinical Diagnostics

Lucy F. Stead, G. Taylor, P. Quirke, 2013, Human mutation.

Growth factor expression during rat development: a comparison of TGF-beta 3, TGF-alpha, bFGF, PDGF and PDGF-R.

P. Quirke, P. Burton, S. Nehlsen-Cannarella, 1993, International journal of experimental pathology.

Flow cytofluorometric analysis of serial biopsies of tumours of the uterine cervix.

P. Quirke, C. Bird, J. Dyson, 1984, European journal of cancer & clinical oncology.

Prospector: A web-based tool for rapid acquisition of gold standard data for pathology research and image analysis

Derek R. Magee, Philip Quirke, Alexander I. Wright, 2015, Journal of pathology informatics.

Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer

J. Barrett, H. Hurwitz, P. Quirke, 2017, JAMA oncology.

Performance and interaction behaviour during visual search on large, high-resolution displays

Roy A. Ruddle, Rebecca Randell, Darren Treanor, 2015, Inf. Vis..

Local recurrence after rectal cancer resection is strongly related to the plane of surgical dissection and is further reduced by pre-operative short course radiotherapy. Preliminary results of the Medical Research Council (MRC) CR07 trial.

J. Monson, R. Stephens, P. Quirke, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

carcinomarole of microsatellite instability in gastric

P. Quirke, L. Cawkwell, I. Martin, 2006 .

P QUIRKE carcinoma The role of microsatellite instability in gastric

P. Quirke, 1998 .

FOCUS 3: A study to determine the feasibility of molecular selection of therapy using K-RAS, B-RAF, and topo-1 in patients with advanced colorectal cancer (ACRC).

M. Parmar, Geraint T. Williams, R. Butler, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS

C. Hurt, P. Quirke, G. Griffiths, 2018, British Journal of Cancer.

Working at the microscope: analysis of the activities involved in diagnostic pathology

Rebecca Randell, Darren Treanor, Phil Quirke, 2012, Histopathology.

ARISTOTLE: A phase III trial comparing concurrent capecitabine with capecitabine and irinotecan (Ir) chemoradiation as preoperative treatment for MRI-defined locally advanced rectal cancer (LARC).

P. Quirke, S. Bach, R. Glynne-Jones, 2020 .

The need for a revised staging system of metastatic (M) colorectal cancer (CRC): Evidence from a national perspective on survival following surgically treated (HPX) liver metastases.

D. Forman, P. Quirke, E. Morris, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Clarifying the TNM staging of rectal cancer in the context of modern imaging and neo‐adjuvant treatment: ‘y’‘u’ and ‘p’ need ‘mr’ and ‘ct’

P. Quirke, D. Cunningham, R. Heald, 2008, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Experiences from the front-line routine consenting of surplus surgically removed tissue: without investment by the National Health Service fully informed consent for all is not available

P. Quirke, M. Agarwal, John Sugden, 2006, Journal of Clinical Pathology.

Acute renal failure complicating Legionnaires' disease.

P. Quirke, D. Warren, M. Harvey, 1980, Postgraduate medical journal.

European guidelines for quality assurance in colorectal cancer screening and diagnosis: Overview and introduction to the full Supplement publication

J. Cuzick, H. Brenner, E. Kuipers, 2012, Endoscopy.

Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice

P. Quirke, D. Lambregts, N. West, 2019, European Radiology.

Exploring the poor outcomes of BRAF mutant (BRAF mut) advanced colorectal cancer (aCRC): Analysis from 2,530 patients (pts) in randomized clinical trials (RCTs).

R. Butler, P. Quirke, J. Cheadle, 2015 .

Preservation of gut microbiome following ridinilazole versus fidaxomicin treatment of Clostridium difficile infection

P. Quirke, M. Wilcox, S. Mitra, 2017 .

Defective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers

D. W. Day, D. Day, N. Shepherd, 2000, Gut.

European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition – Annotations of colorectal lesions

M. Vieth, P. Quirke, M. Risio, 2012, Endoscopy.

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial

R. Butler, P. Quirke, H. Wasan, 2017, The lancet. Gastroenterology & hepatology.

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF , PIK3CA , KRAS , and NRAS (FOCUS4-D): a phase 2–3 randomised trial

R. Butler, P. Quirke, H. Wasan, 2018 .

HER3 as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC)

J. Barrett, K. Owzar, H. Hurwitz, 2015 .

Secrets from the microbiome: molecular biology meets microbiology meets histopathology … meets clinical biochemistry

P. Quirke, C. Young, 2015, Annals of clinical biochemistry.

Molecular biology made easy. The polymerase chain reaction

P. Quirke, P. Quirke, N. Mapstone, 1992, The Histochemical Journal.

Detection of c-Ki-ras mutations in bile samples from patients with pancreatic and biliary cancers

A. Axon, P. Quirke, M. Longfellow, 1995, Clinical molecular pathology.

Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.

G. Taylor, P. Quirke, S. Bell, 1993, Gastroenterology.

IntAct: intra‐operative fluorescence angiography to prevent anastomotic leak in rectal cancer surgery: a randomized controlled trial

V. Goh, D. Miskovic, P. Quirke, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Prenatal detection of trisomy 13 from amniotic fluid by quantitative fluorescent polymerase chain reaction

P. Quirke, B. Nagy, T. Marton, 1998, Prenatal diagnosis.

The polymerase chain reaction: The route to molecular histopathology

G. Taylor, P. Quirke, P. Quirke, 1989, The Journal of pathology.

The evolutionary landscape of colorectal tumorigenesis

Ville Mustonen, Andrea Sottoriva, Xiaowei Jiang, 2018, Nature Ecology & Evolution.

Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study

Jakob Nikolas Kather, P. A. van den Brandt, H. Grabsch, 2023, Cancer cell.

Deletion of Chromosome 4q Predicts Outcome in Stage II Colon Cancer Patients

H. Grabsch, M. Cuesta, B. Ylstra, 2010, Analytical Cellular Pathology.

Antagonist. Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease.

P. Quirke, 2001, Gut.

545P Epidermal growth factor receptor (EGFR) copy number (CN) as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC)

J. Barrett, P. Quirke, F. Elliott, 2017 .

Association of topoisomerase-1 (Topo1) with the efficacy of chemotherapy in a randomized trial for advanced colorectal cancer patients (FOCUS).

M. Parmar, P. Quirke, P. Selby, 2006, Journal of Clinical Oncology.

Hodgkin's disease: a flowcytometric study

P. Quirke, K. Morgan, 1988 .

Virtual reality Powerwall versus conventional microscope for viewing pathology slides: an experimental comparison

Phil Quirke, Darren Treanor, Jason Wood, 2009, Histopathology.

I. Nagtegaal, R. Gray, C. Punt, 2017, BMJ Open.

Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference

M. Morino, K. Bujko, P. Quirke, 2015, Surgical Endoscopy.

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

I. Nagtegaal, B. Ylstra, G. Meijer, 2014, Clinical Cancer Research.

Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer.

D. Kerr, S. Shak, F. Baehner, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

What is the role for the circumferential margin in the modern treatment of rectal cancer?

I. Nagtegaal, P. Quirke, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

KRAS and BRAF Mutational Status can be Accurately Determined on Diagnostic Tissue Biopsies: An Analysis of Matched Biopsy and Resection Material from Patients with Colon Cancer in the NCRI FOxTROT trial

R. Gray, B. Warren, P. Quirke, 2012 .

Pathologic Processing of the Total Mesorectal Excision

P. Quirke, Susanne W. Carmack, Molly M Campa-Thompson, 2015, Clinics in Colon and Rectal Surgery.

IntAct: intra‐operative fluorescence angiography to prevent anastomotic leak in rectal cancer surgery: a randomized controlled trial

V. Goh, D. Miskovic, P. Quirke, 2018, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Investigating the Faecal Microbiome in Formalin Fixed Paraffin Embedded (FFPE) Material

P. Quirke, H. Wood, M. Taylor, 2015 .

Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy.

A. Axon, P. Quirke, N. Mapstone, 1995, Gut.

Summary of product characteristics

D. Jayne, P. Quirke, N. Corrigan, 2016 .

Heterogeneity of colorectal adenocarcinomas evaluated by flow cytometry and histopathology.

P. Quirke, C. Bird, M. Dixon, 1985, British Journal of Cancer.

DNA aneuploidy in colorectal adenomas.

P. Quirke, M. Dixon, J. Dyson, 1986, British Journal of Cancer.

Accurately Identifying Low‐Allelic Fraction Variants in Single Samples with Next‐Generation Sequencing: Applications in Tumor Subclone Resolution

Lucy F. Stead, G. Taylor, P. Quirke, 2013, Human mutation.

Virtual reality microscope versus conventional microscope regarding time to diagnosis: an experimental study

Claudia Mello-Thoms, Rebecca Randell, Darren Treanor, 2013, Histopathology.

Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial

M. D. James, R. Butler, P. Quirke, 2015, Journal of Clinical Pathology.

OC-0219 THE MRC CR07 TRIAL NCIC CO16 TRIAL AFTER A MEDIAN FOLLOW UP OF 8 YEARS

J. Monson, P. Quirke, D. Sebag‐Montefiore, 2012 .

Molecular markers and the prediction of prognosis and response to therapy in colon cancer

Matthew T. Seymour, Pl Barratt, Sally P. Stenning, 1999 .

Adventitial fibromuscular dysplasia and ischaemic bowel

P. Quirke, S. Widgren, J. Cox, 1984 .

Who to treat with adjuvant therapy in Dukes B/stage II colorectal cancer? The need for high quality pathology

D. Forman, P. Quirke, N. Maughan, 2007, Gut.

Incorporating Local and Global Context for Better Automated Analysis of Colorectal Cancer on Digital Pathology Slides

Derek R. Magee, Darren Treanor, Philip Quirke, 2016, MIUA.

Significant Individual Variation Between Pathologists in the Evaluation of Colon Cancer Specimens After Complete Mesocolic Excision

S. Laurberg, P. Quirke, N. West, 2016, Diseases of the colon and rectum.

DNA methylation, a biomarker for colorectal cancer: implications for screening and pathological utility.

A. Jubb, P. Quirke, A. J. Oates, 2003, Annals of the New York Academy of Sciences.