J. Xiong

发表

The three-dimensional structures of methanol dehydrogenase from two methylotrophic bacteria at 2.6-A resolution.

F. S. Mathews, Z. Xia, W. Dai, 1992, The Journal of biological chemistry.

CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHA VBETA3 BOUND TO MN2

A. Joachimiak, M. Arnaout, J. Xiong, 2002 .

Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

Thilo Stehle, Rongguang Zhang, M. Amin Arnaout, 2002, Science.

Crystal Structure of the Extracellular Segment of Integrin αVβ3

Thilo Stehle, M. Amin Arnaout, Jian-Ping Xiong, 2001, Science.

Integrin structure, allostery, and bidirectional signaling.

M. Arnaout, J. Xiong, B. Mahalingam, 2005, Annual review of cell and developmental biology.

Expression and purification of functional human anthrax toxin receptor (ATR/TEM8) binding domain from Escherichia coli.

Kenneth A Bradley, Zhiping Ding, Jian-Ping Xiong, 2006, Protein expression and purification.

A Novel Adaptation of the Integrin PSI Domain Revealed from Its Crystal Structure*

Thilo Stehle, Jian-Ping Xiong, M. Arnaout, 2004, Journal of Biological Chemistry.

An Isoleucine-based Allosteric Switch Controls Affinity and Shape Shifting in Integrin CD11b A-domain*

M. Arnaout, J. Xiong, T. Stehle, 2000, The Journal of Biological Chemistry.

Structure-guided design of novel orthosteric inhibitors of integrin αIIbβ3 that prevent thrombosis but preserve hemostasis

M. Arnaout, J. Xiong, Shu-Wha Lin, 2019, bioRxiv.

Atomic Basis for the Species-specific Inhibition of αV Integrins by Monoclonal Antibody 17E6 Is Revealed by the Crystal Structure of αVβ3 Ectodomain-17E6 Fab Complex*

M. Mofrad, M. Arnaout, J. Xiong, 2014, The Journal of Biological Chemistry.

Crystal Structure of the Complete Integrin

J. Xiong, S. Goodman, J. Alonso, 2009 .

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

M. Arnaout, J. Xiong, Shu-Wha Lin, 2020, Nature Communications.

Structure-guided design of a pure orthosteric antagonist of integrin αlIbβ3 that inhibits thrombosis but not clot retraction

M. Arnaout, J. Xiong, M. Poncz, 2018 .

Adhesion Site Face of Integrin CD11b Directed to the Metal Ion-Dependent Sensitive Murine Monoclonal Antibody Characterization of a Conformationally

P. Rieu, M. Arnaout, J. Xiong, 2002 .

The α-Subunit Regulates Stability of the Metal Ion at the Ligand-associated Metal Ion-binding Site in β3 Integrins*

M. Mofrad, M. Arnaout, J. Xiong, 2014, The Journal of Biological Chemistry.

Role of the β-subunit arginine/lysine finger in integrin heterodimer formation and function

M. Arnaout, J. Xiong, J. Alonso, 2008, The Journal of Immunology.

Regulation of α5β1 integrin conformation and function by urokinase receptor binding

J. Xiong, M. Humphries, R. Czekay, 2005, The Journal of cell biology.

Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands*

W. H. Goldmann, W. Goldmann, M. Arnaout, 2004, Journal of Biological Chemistry.

Structural basis for pure antagonism of integrin αVβ3 by a high affinity form of fibronectin

José Luis Alonso, M. Amin Arnaout, Jian-Ping Xiong, 2014, Nature Structural &Molecular Biology.

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

Bradley T. Hyman, M. Amin Arnaout, Jian-Ping Xiong, 2009, The Journal of cell biology.

The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18.

M. Arnaout, J. Xiong, J. Alonso, 2007, Blood.

Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin

Mark Yeager, M. Amin Arnaout, Jian-Ping Xiong, 2005, The Journal of cell biology.

Three-dimensional EM structure of the ectodomain of integrin (cid:1) V (cid:2) 3 in a complex with ﬁbronectin

M. Yeager, M. Arnaout, J. Xiong, 2005 .

The (cid:1) -tail domain ( (cid:1) TD) regulates physiologic ligand binding to integrin CD11b/CD18

M. Arnaout, J. Xiong, J. Alonso, 2007 .

Does the integrin alphaA domain act as a ligand for its betaA domain?

M. Arnaout, J. Xiong, T. Stehle, 2002, Current biology : CB.

CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3

A. Joachimiak, M. Arnaout, J. Xiong, 2001 .

Cloning and Characterization of a Mammalian Lithium-sensitive Bisphosphate 3′-Nucleotidase Inhibited by Inositol 1,4-Bisphosphate*

J. York, J. Xiong, J. Smith, 1999, The Journal of Biological Chemistry.

Crystal structure of trichosanthin-NADPH complex at 1.7Å resolution reveals active-site architecture

Z. Xia, J. Xiong, Yu Wang, 1994, Nature Structural Biology.

BETA-MOMORCHARIN STRUCTURE AT 2.55 A

Z. Xia, J. Xiong, Y.-R. Yuan, 1999 .

Three-dimensional structure of beta-momorcharin at 2.55 A resolution.

Z. Xia, J. Xiong, Y. Yuan, 1999, Acta crystallographica. Section D, Biological crystallography.

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

M. Arnaout, J. Xiong, Shu-Wha Lin, 2020, Nature Communications.

Recombinant integrin CD11b A‐domain blocks polymorphonuclear cells recruitment and protects against skeletal muscle inflammatory injury in the rat

M. Arnaout, J. Xiong, S. Boubaker, 2006, Immunology.

Structural basis of the differential binding of engineered knottins to integrins αVβ3 and α5β1

M. Mofrad, M. Arnaout, J. Xiong, 2019, bioRxiv.

New insights into the structural basis of integrin activation.

Thilo Stehle, Jian-Ping Xiong, M. Arnaout, 2003, Blood.

Structure and mechanics of integrin-based cell adhesion.

Jian-Ping Xiong, M. Arnaout, J. Xiong, 2007, Current opinion in cell biology.

Purification, analysis, and crystal structure of integrins.

M. Arnaout, J. Xiong, S. Goodman, 2007, Methods in enzymology.

Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme

B. Matthews, W. Baase, I. Vetter, 1996, Protein science : a publication of the Protein Society.

Integrins, cations and ligands: making the connection

M. Arnaout, J. Xiong, T. Stehle, 2003, Journal of thrombosis and haemostasis : JTH.

Does the Integrin αA Domain Act as a Ligand for its βA Domain?

M. Arnaout, J. Xiong, T. Stehle, 2002, Current Biology.

EM Structure of the Ectodomain of Integrin CD11b/CD18 and Localization of Its Ligand-Binding Site Relative to the Plasma Membrane

B. Hyman, M. Arnaout, J. Xiong, 2013, PloS one.

Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design

Alberto L. Horenstein, José Luis Alonso, M. Amin Arnaout, 2011, The Journal of Immunology.

Structure-based Drug Design Implications for Integrin Regulation and Antibody-derived Ligand Aspartate: Site in Integrin Cd11b/cd18 by an Ion at the Metal Ion-dependent Adhesion 2+ Stable Coordination of the Inhibitory Ca

J. Xiong, F. Malavasi, B. Adair, 2022 .

Characterization of a Conformationally Sensitive Murine Monoclonal Antibody Directed to the Metal Ion-Dependent Adhesion Site Face of Integrin CD11b1

P. Rieu, M. Arnaout, J. Xiong, 2002, The Journal of Immunology.

The β-tail domain (βTD) regulates physiologic ligand binding to integrin CD11b/CD18

M. Arnaout, J. Xiong, J. Alonso, 2007 .

Coming to grips with integrin binding to ligands.

M. Arnaout, J. Xiong, S. Goodman, 2002, Current opinion in cell biology.

A structural basis for lithium and substrate binding of an inositide phosphatase

J. Ponder, J. York, J. Xiong, 2020, The Journal of biological chemistry.

Atomic basis for the species-specific inhibition of alpha V integrins by monoclonal antibody 17E6 is revealed by the crystal structure of alpha V beta 3 ectodomain-17E6 Fab complex.

M. Mofrad, J. Xiong, S. Goodman, 2014 .

Structure of Antibody 17 E 6 Is Revealed by the Crystal V Integrins by Monoclonal α Inhibition of Atomic Basis for the Species-specific Protein Structure and Folding :

M. Arnaout, J. Xiong, S. Goodman, 2014 .

Role of the β-Subunit Arginine/Lysine Finger in Integrin Heterodimer Formation and Function1

M. Arnaout, J. Xiong, J. Alonso, 2008, The Journal of Immunology.

Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function.

M. Arnaout, J. Xiong, M. Essafi, 2008, Journal of immunology.

Cryo-EM structures of full-length integrin αIIbβ3 in native lipids

M. Yeager, J. Xiong, B. Adair, 2023, Nature communications.

Expression and purification of functional human anthrax toxin receptor (ATR/TEM8) binding domain from Escherichia coli.

J. Xiong, K. Bradley, Zhiping Ding, 2006, Protein Expression and Purification.

J. Xiong, F. Malavasi, B. Adair, 2011, The Journal of Immunology.

The (cid:2) -Subunit Regulates Stability of the Metal Ion at the Ligand-associated Metal Ion-binding Site in (cid:3) 3 Integrins *

M. Arnaout, J. Xiong, M. Mehrbod, 2014 .

New Insights into the Structural Basis of Integrin Activation

J. Xiong, M. Amin Arnaout, Thilo Stehle, 2003 .

Atomic basis for the species-specific inhibition of alpha V integrins by monoclonal antibody 17E6 is revealed by the crystal structure of alpha V beta 3 ectodomain-17E6 Fab complex.

J. Xiong, S. Goodman, M. Mehrbod, 2014 .

Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin

M. Arnaout, J. Xiong, S. Goodman, 2005, The Journal of cell biology.