J. Varghese

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Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2.2 A resolution.

P. Colman, J. Varghese, 1991, Journal of molecular biology.

Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex.

W G Laver, R. Webster, P. Colman, 1992, Journal of molecular biology.

Structure of the catalytic and antigenic sites in influenza virus neuraminidase

J. N. Varghese, P. Colman, J. Varghese, 1983, Nature.

Rational design of potent sialidase-based inhibitors of influenza virus replication

D. M. Ryan, P. Colman, J. Varghese, 1993, Nature.

Enhanced uptake of an integral membrane protein, the dopamine D2L receptor, by cubic nanostructured lipid nanoparticles doped with Ni(II) chelated EDTA amphiphiles

C. Drummond, J. Varghese, S. Sagnella, 2011 .

High-throughput production and structural characterization of libraries of self-assembly lipidic cubic phase materials.

Shane A. Seabrook, C. Drummond, J. Newman, 2012, ACS combinatorial science.

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

P. Colman, J. Varghese, A. Kortt, 1992, Proteins.

Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases.

A. van Donkelaar, P. Colman, J. Varghese, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.

Paul W Smith, P. Colman, J. Varghese, 1998, Structure.

Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution

J. N. Varghese, P. Colman, J. Varghese, 1983, Nature.

Antigenic structure and variation in an influenza virus N9 neuraminidase

G. Air, R. Webster, D. Metzger, 1987, Journal of virology.

Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en.

P. Colman, J. Varghese, R. Bethell, 1995, Virology.

Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides

Paul W Smith, P. Colman, J. Varghese, 1996 .

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

J. N. Varghese, P. A. Tulloch, G. Air, 1987, Nature.

Mutations in a Conserved Residue in the Influenza Virus Neuraminidase Active Site Decreases Sensitivity to Neu5Ac2en-Derived Inhibitors

P. Colman, J. Varghese, R. Bethell, 1998, Journal of Virology.

Three‐dimensional structure of neuraminidase of subtype N9 from an avian influenza virus

G. Air, P. Colman, J. Varghese, 1987, Proteins.

Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site

J. Varghese, Jean‐Didier Maréchal, J. M. Lluch, 2019, Nature Communications.

Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities.

P. Colman, L. Chen, J. Varghese, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Three-dimensional structure of the complex of 4-guanidino-NeuSAc2en and influenza virus neuraminidase

P. Colman, J. Varghese, Chandana Epa, 2002 .

Modelling Copper Binding to the Amyloid-β Peptide in Alzheimer

J. Varghese, V. Streltsov, V. Epa, 2010 .

Substrate mediated reduction of copper-amyloid-beta complex in Alzheimer's disease.

J. Varghese, V. Streltsov, 2008, Chemical communications.

A New Method to Measure Cellular Toxicity of Non-Fibrillar and Fibrillar Alzheimer's Aβ Using Yeast

I. Macreadie, J. Varghese, L. Waddington, 2008 .

Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages.

K. Moore, J. Varghese, C. Stewart, 2005, Biochemistry.

The 3-Dimensional Structures of Influenza Virus Neuraminidase and an Antineuraminidase Fab Fragment

R. Webster, P. Colman, J. Varghese, 1987 .

Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain.

A. van Donkelaar, R. Moritz, J. Varghese, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Crystallization and preliminary X-ray analysis of (1,3)- and (1,3;1,4)-beta-D-glucanases from germinating barley.

L. Chen, J. Varghese, G. Fincher, 1993, Journal of molecular biology.

Alzheimer's amyloid-beta rescues yeast from hydroxide toxicity.

I. Macreadie, J. Varghese, P. Bharadwaj, 2009, Journal of Alzheimer's disease : JAD.

Spin density and structure of aquabis(2,2′-bipyridine)di-µ-hydroxosulphatodicopper(II) tetrahydrate at 4.2 K

Geoffrey A. Williams, J. Varghese, B. Figgis, 1983 .

Electron density in non-ideal metal complexes. I. Copper sulphate pentahydrate

J. Varghese, E. N. Maslen, 1985 .

Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.

P. Colman, J. Varghese, A. Wonacott, 2001, Bioorganic & medicinal chemistry letters.

SPIN DENSITY AND STRUCTURE OF AQUABIS(2,2′-BIPYRIDINE)DI-μ-HYDROXOSULFATODICOPPER(II) TETRAHYDRATE AT 4.2 K

Geoffrey A. Williams, J. Varghese, B. Figgis, 1983 .

Crystal structures of trans-Dichloro- and Dibromo-bis(2,6-dimethylpyridine)copper(II)

J. Varghese, C. Raston, A. White, 1977 .

The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.

C. Masters, J. Varghese, V. Streltsov, 2008, Biophysical journal.

The X-ray and neutron crystal structure of 2,4,6-triamino-1,3,5-triazine (melamine)

J. Varghese, A. M. O'Connell, E. N. Maslen, 1977 .

Electron densities in transition metal complexes: population analysis of polarized neutron diffraction data

J. Varghese, R. Mason, 1980, Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences.

Development of neuraminidase inhibitors as anti‐influenza virus drugs

J. Varghese, Joseph N. Varghese, 1999 .

Three-dimensional Structure of the Barley β-d-Glucan Glucohydrolase in Complex with a Transition State Mimic*

Brian J. Smith, J. Varghese, A. Vasella, 2004, Journal of Biological Chemistry.

Three-dimensional structures of influenza virus neuraminidase-antibody complexes.

G. Air, R. Webster, P. Colman, 1989, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Three-dimensional structure of a barley beta-D-glucan exohydrolase, a family 3 glycosyl hydrolase.

J. Varghese, G. Fincher, M. Hrmova, 1999, Structure.

Analysis of inhibitor binding in influenza virus neuraminidase

Brian J. Smith, P. Colman, J. Varghese, 2001, Protein science : a publication of the Protein Society.

Polysaccharide hydrolases in germinated barley and their role in the depolymerization of plant and fungal cell walls.

J. Varghese, G. Fincher, M. Hrmova, 1997, International journal of biological macromolecules.

The three‐dimensional structure of the seed storage protein phaseolin at 3 A resolution.

A. van Donkelaar, P. Colman, J. Varghese, 1990, The EMBO journal.

Structural Basis for Broad Substrate Specificity in Higher Plant β-d-Glucan Glucohydrolases Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010442.

Brian J. Smith, J. Varghese, G. Fincher, 2002, The Plant Cell Online.

Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III.

M. Lawrence, P. Colman, P. Pilling, 2004, Journal of molecular biology.

Validation of folate in a convenient yeast assay suited for identification of inhibitors of Alzheimer's amyloid-beta aggregation.

I. Macreadie, J. Varghese, L. Bennett, 2008, Journal of Alzheimer's disease : JAD.

Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site

J. Varghese, Jean‐Didier Maréchal, J. M. Lluch, 2019, Nature Communications.

Comparative modeling of the three‐dimensional structures of family 3 glycoside hydrolases

J. Varghese, G. Fincher, M. Hrmova, 2000, Proteins.

Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.

R. Webster, P. Colman, J. Varghese, 1992, Journal of molecular biology.

Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants.

A. van Donkelaar, R. Webster, P. Colman, 1992, Journal of molecular biology.

Structure of an escape mutant of glycoprotein N2 neuraminidase of influenza virus A/Tokyo/3/67 at 3 A.

R. Webster, P. Colman, J. Varghese, 1988, Journal of molecular biology.

Structural studies of the tethered N‐terminus of the Alzheimer's disease amyloid‐β peptide

C. Masters, J. Varghese, O. Dolezal, 2013, Proteins.

Structure of the extracellular domains of the human interleukin-6 receptor α-chain

A. van Donkelaar, R. Moritz, J. Varghese, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Brian J. Smith, J. Varghese, G. Fincher, 2002, The Plant Cell Online.

Catalytic mechanisms and reaction intermediates along the hydrolytic pathway of a plant beta-D-glucan glucohydrolase.

Brian J. Smith, J. Varghese, G. Fincher, 2001, Structure.

Statistical geometry. I. A self-consistent approach to the crystallographic inversion problem based on information theory

Stephen W. Wilkins, M. S. Lehmann, S. Wilkins, 1983 .

Protein Crystal Diffraction Patterns Using a Capillary-Focused Synchrotron X-ray Beam.

K. Nugent, S. Wilkins, J. Varghese, 1996, Journal of synchrotron radiation.

Alzheimer's Aβ fused to green fluorescent protein induces growth stress and a heat shock response

P. Macreadie, I. Macreadie, J. Varghese, 2007 .

Alzheimer's Abeta fused to green fluorescent protein induces growth stress and a heat shock response.

P. Macreadie, I. Macreadie, J. Varghese, 2007, FEMS yeast research.

Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley.

Brian J. Smith, J. Varghese, A. Vasella, 2005, Biochemistry.

Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.

P. Colman, J. Varghese, J. McKimm-Breschkin, 1998, Virology.

Three‐dimensional structure of the complex of 4‐guanidino‐Neu5Ac2en and influenza virus neuraminidase

P. Colman, J. Varghese, Joseph N. Varghese, 1995, Protein science : a publication of the Protein Society.

Structural studies of the resistance of influenza virus neuramindase to inhibitors.

Brian J Smith, Brian J. Smith, P. Colman, 2002, Journal of medicinal chemistry.

Cell wall degrading enzymes in barley.

J. Varghese, G. Fincher, M. Tenkanen, 2000 .

Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor.

J. Varghese, P. Hudson, V. Streltsov, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Crystal Structure of the Amyloid-β p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease

Colin L Masters, C. Masters, J. Varghese, 2011, The Journal of Neuroscience.

Alzheimer ’ sA b fused togreen £ uorescent protein induces growth stress anda heat shock response

P. Macreadie, I. Macreadie, J. Varghese, 2007 .

Comparative Modeling of the Three-Dimensional Structures and Phylogenetic Analysis of Family 3 Glycoside Hydrolases

J. Varghese, G. Fincher, M. Hrmova, 2000 .

Oligomerization and toxicity of Aβ fusion proteins.

G. Ciccotosto, J. Varghese, V. Streltsov, 2011, Biochemical and biophysical research communications.

2 Oligomerization and toxicity of Ab fusion proteins

G. Ciccotosto, J. Varghese, V. Streltsov, 2011 .

Crystal structures of neuraminidase-antibody complexes.

G. Air, R. Webster, P. Colman, 1989, Cold Spring Harbor symposia on quantitative biology.

7 – Recognition of Protein Antigens by Antibodies: Crystal Structure of Antibody Fab Fragments Complexed with Influenza Virus Neuraminidase

G. Air, R. Webster, P. Colman, 1990 .

A new method to measure cellular toxicity of non-fibrillar and fibrillar Alzheimer's Abeta using yeast.

I. Macreadie, J. Varghese, L. Waddington, 2008, Journal of Alzheimer's disease : JAD.

Crystallization and preliminary X-ray analysis of beta-glucan exohydrolase isoenzyme ExoI from barley (Hordeum vulgare).

J. Varghese, G. Fincher, M. Hrmova, 1998, Acta crystallographica. Section D, Biological crystallography.

Incorporation of the dopamine D2L receptor and bacteriorhodopsin within bicontinuous cubic lipid phases. 2. Relevance to in meso crystallization of integral membrane proteins in novel lipid systems

C. Drummond, J. Varghese, S. Sagnella, 2010 .

On exact analytical solutions for the few-particle Schrödinger equation. I. A perturbation study

J. Varghese, E. Maslen, C. L. Davis, 1982, Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences.

Naturally occurring polyphenolic inhibitors of amyloid beta aggregation.

J. Varghese, V. Streltsov, Kate Cavanagh, 2014, Bioorganic & medicinal chemistry letters.

influenza virus N9 neuraminidase. Antigenic structure and variation in an

G. Air, R. Webster, D. Metzger, 2013 .

Mutant barley (1→3,1→4)-β-glucan endohydrolases with enhanced thermostability

J. Varghese, G. Fincher, P. Høj, 2001 .

Substrate mediated reduction of copper-amyloid-beta complex in Alzheimer's disease.

J. Varghese, V. Streltsov, 2008, Chemical communications.

Amyloid-beta-peptid-kristallstruktur

J. Varghese, V. Streltsov, S. Nuttall, 2009 .