D. Lambright

发表

The 2.0 Å crystal structure of a heterotrimeric G protein

H. Hamm, P. Sigler, J. Sondek, 1996, Nature.

Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis

Lawrence M. Lifshitz, Lawrence M Lifshitz, Clive Standley, 2012, Proceedings of the National Academy of Sciences.

The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis

C. Mello, D. Lambright, S. Corvera, 2006, Proceedings of the National Academy of Sciences.

Biophysical basis of cellular multi-specificity encoded in a model molecular switch

Robyn M. Kaake, Gwendolyn M. Jang, Christopher J. P. Mathy, 2020, bioRxiv.

Structural Basis for Endosomal Targeting by FYVE Domains*

D. Lambright, S. Corvera, K. Fogarty, 2004, Journal of Biological Chemistry.

X-ray crystal structure of a recombinant human myoglobin mutant at 2.8 A resolution.

S. Hubbard, S. Boxer, W. Hendrickson, 1990, Journal of molecular biology.

Crystal structure of a GA protein βγdimer at 2.1 Å resolution

Andrew Bohm, Heidi E. Hamm, John Sondek, 1996, Nature.

Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes

J. Cherfils, T. Irving, D. Lambright, 2019, Structure.

Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors

T. Irving, D. Lambright, O. Bilsel, 2017, Structure.

A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.

R. Kahn, D. Lambright, 2015, Structure.

Determination of the carbon monoxide binding constants of myoglobin mutants: comparison of kinetic and equilibrium methods.

S. Boxer, D. Lambright, S. Gill, 1994, Biochemistry.

Anatomy and dynamics of a ligand-binding pathway in myoglobin: the roles of residues 45, 60, 64, and 68.

S. Boxer, D. Lambright, S G Boxer, 1994, Biochemistry.

Membrane and juxtamembrane targeting by PH and PTB domains.

D. Lambright, Jonathan P DiNitto, David G Lambright, 2006, Biochimica et biophysica acta.

Grp1 plays a key role in linking insulin signaling to glut4 recycling.

M. Famulok, D. Lambright, H. Sabe, 2012, Developmental cell.

Association-dissociation modulation of enzyme activity: case of lactose synthase.

D. Lambright, S. Wong, T. K. Lee, 1985, Biochemistry.

Dynamics of protein relaxation in site-specific mutants of human myoglobin.

S. Boxer, D. Lambright, S. Balasubramanian, 1993, Biochemistry.

MAP Kinase Signaling Specificity

D. Lambright, Roger J. Davis, C. Weston, 2002, Science.

An endocytic pathway as a target of tubby for regulation of fat storage

D. Lambright, H. Tissenbaum, A. Mukhopadhyay, 2007, EMBO reports.

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

P. De Camilli, D. Lambright, H. Nagai, 2014, PLoS pathogens.

ART2, a T Cell Surface Mono-ADP-ribosyltransferase, Generates Extracellular Poly(ADP-ribose)*

James E. Evans, J. Moss, D. Lambright, 2006, Journal of Biological Chemistry.

Membrane Trafficking: An Endosome Tether Meets a Rab and Collapses

D. Lambright, Sanchaita Das, 2016, Current Biology.

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

D. Lambright, S. Corvera, S. Eathiraj, 2010, Proceedings of the National Academy of Sciences.

Essential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization.

Lawrence M. Lifshitz, D. Lambright, A. Chawla, 2003, Molecular biology of the cell.

RUTBC2 Protein, a Rab9A Effector and GTPase-activating Protein for Rab36*

D. Lambright, S. Pfeffer, I. Ganley, 2012, The Journal of Biological Chemistry.

Sequential Roles for Phosphatidylinositol 3-Phosphate and Rab5 in Tethering and Fusion of Early Endosomes via Their Interaction with EEA1* 210

Lawrence M. Lifshitz, D. Lambright, A. Chawla, 2002, The Journal of Biological Chemistry.

ESCRT complexes assembled and GLUEd.

D. Lambright, S. Eathiraj, 2006, Structure.

Effects of applied electric fields on the quantum yields of the initial electron-transfer steps in bacterial photosynthesis. 1. Quantum yield failure

R. J. Stanley, S. Boxer, D. Lambright, 1993 .

Structural Mechanisms for Regulation of Membrane Traffic by Rab GTPases

D. Lambright, A. Mishra, Meng‐Tse Gabe Lee, 2009, Traffic.

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.

H. Hamm, J. Noel, P. Sigler, 1995, Nature.

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.

H. Hamm, J. Noel, P. Sigler, 1994, Nature.

Rab GEFs and GAPs.

D. Lambright, F. Barr, 2010, Current opinion in cell biology.

Legionella pneumophila proteins that regulate Rab1 membrane cycling

D. Lambright, C. Roy, A. Delprato, 2007, Nature.

TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism

D. Lambright, M. Munson, S. Eathiraj, 2006, Nature.

Perturbations of the distal heme pocket in human myoglobin mutants probed by infrared spectroscopy of bound CO: correlation with ligand binding kinetics.

S. Boxer, D. Lambright, S. Balasubramanian, 1993, Proceedings of the National Academy of Sciences of the United States of America.

High-Throughput Assay for Profiling the Substrate Specificity of Rab GTPase-Activating Proteins.

D. Lambright, A. Mishra, 2021, Methods in molecular biology.

High-throughput assay for profiling the substrate specificity of Rab GTPase-activating proteins.

D. Lambright, A. Mishra, 2015, Methods in molecular biology.

The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor

D. Toomre, D. Lambright, T. Murata, 2006, Nature Cell Biology.

Germline mutations affecting Gα11 in hypoparathyroidism.

S. Gabriel, M. Daly, D. Lambright, 2013, The New England journal of medicine.

Determinants of Rab5 Interaction with the N Terminus of Early Endosome Antigen 1*

D. Lambright, C. Stone, S. Eathiraj, 2003, The Journal of Biological Chemistry.

The FYVE Domain of Early Endosome Antigen 1 Is Required for Both Phosphatidylinositol 3-Phosphate and Rab5 Binding

D. Lambright, V. Patki, S. Corvera, 2000, The Journal of Biological Chemistry.

Specificity and membrane partitioning of Grsp1 signaling complexes with Grp1 family Arf exchange factors.

D. Lambright, Andrew W. Malaby, J. P. DiNitto, 2010, Biochemistry.

CO recombination to human myoglobin mutants in glycerol-water solutions.

S. Boxer, D. Lambright, M. Marden, 1993, Biochemistry.

Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking

C. Ackerley, C. Ross, W. Wasserman, 2014, Orphanet Journal of Rare Diseases.

Coordination of Grp1 recruitment mechanisms by its phosphorylation

D. Lambright, V. Hsu, Jian Li, 2020, Molecular biology of the cell.

Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin.

S. Boxer, D. Lambright, J. Petrich, 1994, Journal of molecular biology.

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

H. Hamm, J. Noel, P. Sigler, 1994, Nature.

Electrostatic interactions in wild-type and mutant recombinant human myoglobins.

S. Boxer, R. Varadarajan, D. Lambright, 1989, Biochemistry.

Inclusion of a small molecule in a big cage: preparation and structure of catena-[catena-(.alpha.,.omega.-diaminooctane)cadmium-.mu.-tetracyanonickelate]-toluene(1/1)

K. Hodgson, D. Lambright, S. Franzen, 1991 .

Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.

D. Lambright, M. Czech, A. Guilherme, 2007, Molecular cell.

Lactose synthase: effect of α-lactalbumin on substrate activity of N-acylglucosamines

D. Lambright, S. Wong, Dennis R. Johnson, 1985 .

Effects of applied electric fields on the quantum yields for the initial electron transfer steps in bacterial photosynthesis. II. Dynamic Stark effect

S. Boxer, D. Lambright, S. Franzen, 1995 .

The Membrane‐Associated Protein, Supervillin, Accelerates F‐Actin‐Dependent Rapid Integrin Recycling and Cell Motility

M. Davidson, D. Lambright, K. Wilson, 2010, Traffic.

Invited review: Small GTPases and their GAPs

D. Lambright, A. Mishra, 2016, Biopolymers.

Is a Rab 1 GTPase-activating Protein That Mediates Hepatitis C Virus Replication *

J. Glenn, D. Lambright, S. Pfeffer, 2007 .

The Rab GTPase-Activating Protein TBC1D4/AS160 Contains an Atypical Phosphotyrosine-Binding Domain That Interacts with Plasma Membrane Phospholipids To Facilitate GLUT4 Trafficking in Adipocytes

D. James, D. Lambright, J. Burchfield, 2012, Molecular and Cellular Biology.

Structural basis for Rab GTPase activation by VPS9 domain exchange factors

D. Lambright, A. Delprato, 2007, Nature Structural &Molecular Biology.

Membrane Recognition and Targeting by Lipid-Binding Domains

D. Lambright, T. Cronin, Jonathan P DiNitto, 2003, Science's STKE.

Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.

H. Hamm, P. Sigler, J. Sondek, 1996, Nature.

The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism*

D. Lambright, R. Collins, C. Roy, 2013, The Journal of Biological Chemistry.

Heterotrimeric G-Protein Signaling at Atomic Resolution

D. Lambright, 2010 .

CHAPTER 215 – Heterotrimeric G Protein Signaling at Atomic Resolution

D. Lambright, 2003 .

Structural basis of activation and GTP hydrolysis in Rab proteins.

D. Lambright, Zhongyuan Zhu, Z Zhu, 1999, Structure.

Gsα meets its target – shedding light on a key signal transduction event

D. Lambright, J. Dumas, 1998 .

ARF GTPases and their GEFs and GAPs: concepts and challenges

J. Cherfils, R. Kahn, M. Yohe, 2019, Molecular biology of the cell.

Crystal structure of a G-protein βγ dimer at 2.1 Å resolution

H. Hamm, P. Sigler, J. Sondek, 1996, Nature.

Structural determinants for activation of the α-subunit of a heterotrimeric G protein

Heidi E. Hamm, H. Hamm, J. Noel, 1994, Nature.

A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.

S. Lietzke, D. Lambright, Zhongyuan Zhu, 2001, Biochemistry.

TBC1D20 Is a Rab1 GTPase-activating Protein That Mediates Hepatitis C Virus Replication*

J. Glenn, D. Lambright, S. Pfeffer, 2007, Journal of Biological Chemistry.

TBC1D13 is a RAB35 Specific GAP that Plays an Important Role in GLUT4 Trafficking in Adipocytes

Sean J. Humphrey, D. James, D. Lambright, 2012, Traffic.

Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes

D. Lambright, L. Gangwani, A. Mishra, 2007, Proceedings of the National Academy of Sciences.

Structural basis of family-wide Rab GTPase recognition by rabenosyn-5

D. Lambright, Xiaojing Pan, Sudharshan Eathiraj, 2005, Nature.

Protein relaxation dynamics in human myoglobin

S. Boxer, D. Lambright, S. Balasubramanian, 1991 .

Ligand and proton exchange dynamics in recombinant human myoglobin mutants.

S. Boxer, D. Lambright, S. Balasubramanian, 1989, Journal of molecular biology.

Systems-level effects of allosteric perturbations to a model molecular switch

Robyn M. Kaake, Gwendolyn M. Jang, Christopher J. P. Mathy, 2021, Nature.

Structural Plasticity of an Invariant Hydrophobic Triad in the Switch Regions of Rab GTPases Is a Determinant of Effector Recognition*

D. Lambright, R. Heller-Harrison, D. Lawe, 2001, The Journal of Biological Chemistry.

Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.

D. Lambright, R. Prekeris, S. Eathiraj, 2006, Journal of molecular biology.

Molecular Insights into Rab7‐Mediated Endosomal Recruitment of Core Retromer: Deciphering the Role of Vps26 and Vps35

Y. Kalaidzidis, D. Lambright, S. Datta, 2015, Traffic.

Multivalent endosome targeting by homodimeric EEA1.

D. Lambright, S. Corvera, S. Hayes, 2001, Molecular cell.

Summary Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA 1-enriched endosomes

Lawrence M. Lifshitz, D. Lambright, S. Corvera, 2014 .

Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes

Lawrence M. Lifshitz, D. Lambright, S. Corvera, 2008, Journal of Cell Science.

Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

J. Acharya, E. Fukusaki, T. Bamba, 2014, The Journal of cell biology.

Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.

P. Janmey, D. Lambright, Yu-Hsiu Wang, 2014, Structure.

Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

D. Lambright, M. Czech, T. Cronin, 2004, The EMBO journal.

Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors

D. Lambright, B. van den Berg, Andrew W. Malaby, 2013, Proceedings of the National Academy of Sciences.

A Novel Pleckstrin Homology Domain-containing Protein Enhances Insulin-stimulated Akt Phosphorylation and GLUT4 Translocation in Adipocytes

D. Lambright, J. Holik, Qiong L. Zhou, 2010, The Journal of Biological Chemistry.

Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains.

S. Lietzke, D. Lambright, A. Chawla, 2000, Molecular cell.

RUTBC1 Protein, a Rab9A Effector That Activates GTP Hydrolysis by Rab32 and Rab33B Proteins*

D. Lambright, S. Pfeffer, I. Ganley, 2011, The Journal of Biological Chemistry.

TBC-2 Regulates RAB-5/RAB-7-mediated Endosomal Trafficking in Caenorhabditis elegans

D. Lambright, Marc-André Sylvain, S. Tuck, 2010, Molecular biology of the cell.

Signal transduction. MAP kinase signaling specificity.

D. Lambright, C. Weston, R. Davis, 2002, Science.

Structure, Exchange Determinants, and Family-Wide Rab Specificity of the Tandem Helical Bundle and Vps9 Domains of Rabex-5

D. Lambright, A. Delprato, E. Merithew, 2004, Cell.

5.11 Membrane Recruitment of Signaling Domains

D. Lambright, 2012 .

X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.

G. Pazour, D. Lambright, M. Struck, 2020, Structure.

Rab9 regulation of the Rab GTPase activating protein, RUTBC1

D. Lambright, S. Pfeffer, I. Ganley, 2009 .

Drosophila Sirt 2 / mammalian SIRT 3 deacetylates ATP synthase beta and regulates complex V activity

J. Acharya, E. Fukusaki, T. Bamba, 2016 .

JCB_201404118 1..17

J. Acharya, E. Fukusaki, T. Bamba, 2014 .

Evolutionarily conserved structural and functional roles of the FYVE domain.

D. Lambright, S. Corvera, D. Leonard, 2007, Biochemical Society symposium.

Rab GEFs and GAPs.

D. Lambright, F. Barr, 2010, Current opinion in cell biology.

Determinants of the broad recognition of exocytic Rab GTPases by Mss4.

D. Lambright, A. Delprato, Z. Zhu, 2001, Biochemistry.

RUTBC2 Protein, a Rab9A Effector and GTPase-activating Protein for Rab36*

D. Lambright, S. Pfeffer, I. Ganley, 2012, The Journal of Biological Chemistry.

Methods for analysis of size-exclusion chromatography-small-angle X-ray scattering and reconstruction of protein scattering.

T. Irving, D. Lambright, O. Bilsel, 2015, Journal of applied crystallography.

Propelling COPII vesicle biogenesis at the endoplasmic reticulum.

D. Lambright, Jianjun Duan, 2021, Structure.