Z. Iqbal

发表

Z. Iqbal, M. Toft, 2019, Nature Genetics.

Targeted next generation sequencing reveals a novel intragenic deletion of the TPO gene in a family with intellectual disability.

J. Veltman, C. Gilissen, S. Riazuddin, 2012, Archives of medical research.

Disruption of the podosome adaptor protein TKS4 (SH3PXD2B) causes the skeletal dysplasia, eye, and cardiac abnormalities of Frank-Ter Haar Syndrome.

J. Veltman, P. Ruiz-Lozano, R. Hennekam, 2010, American journal of human genetics.

Identifying Genes Responsible for Intellectual Disability in Consanguineous Families

Z. Iqbal, H. van Bokhoven, 2014, Human Heredity.

Molecular Genetic Studies on 167 Pediatric ALL Patients from Different Areas of Pakistan Confirm a Low Frequency of the Favorable Prognosis Fusion Oncogene TEL-AML 1

Z. Iqbal, 2014 .

Clofarabine in the treatment of elderly patients with acute myeloid leukemia.

Z. Iqbal, K. AlSaleh, Abdulkareem M Almomen, 2013, Asian Pacific journal of cancer prevention : APJCP.

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton

Z. Iqbal, M. Kassem, N. Alajez, 2018, Stem cells international.

Exome Sequencing Identifies Three Novel Candidate Genes Implicated in Intellectual Disability

L. Vissers, R. Pfundt, J. Veltman, 2014, PloS one.

Low Frequency of ETV6-RUNX1 (t 12; 21) in Saudi Arabian Pediatric Acute Lymphoblastic Leukemia Patients: Association with Clinical Parameters and Early Remission.

Z. Iqbal, M. Absar, S. Aloraibi, 2015, Asian Pacific journal of cancer prevention : APJCP.

Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems.

A. V. Vulto-van Silfhout, L. Vissers, T. Wienker, 2015, American journal of human genetics.

Five Most Common Prognostically Important Fusion

Danish, Muhammad, Haq, 2013 .

Five most common prognostically important fusion oncogenes are detected in the majority of Pakistani pediatric acute lymphoblastic leukemia patients and are strongly associated with disease biology and treatment outcome.

S. Basit, Z. Iqbal, M. Sabar, 2012, Asian Pacific journal of cancer prevention : APJCP.

Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients.

M. Kamal, Z. Iqbal, M. Qazi, 2015, Saudi journal of biological sciences.

Two different point mutations in ABL gene ATP-binding domain conferring Primary Imatinib resistance in a Chronic Myeloid Leukemia (CML) patient: A case report

Z. Iqbal, R. Siddiqui, J. Qureshi, 2004, Biological Procedures Online.

High Frequency and Poor Prognosis of Late Childhood BCR-ABL-Positive and MLL-AF4-Positive ALL Define the Need for Advanced Molecular Diagnostics and Improved Therapeutic Strategies in Pediatric B-ALL in Pakistan

Z. Iqbal, M. Sabar, M. Iqbal, 2015, Molecular Diagnosis & Therapy.

Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay

D. Misceo, S. Antonarakis, S. Riazuddin, 2017, Genetics in Medicine.

The D90A mutation results in a polymorphism of Cu,Zn superoxide dismutase that is prevalent in northern Sweden and Finland.

J. Tainer, T. Siddique, Z. Iqbal, 1995, Human molecular genetics.

CHCHD2 and Parkinson's disease

Z. Iqbal, M. Toft, 2015, The Lancet Neurology.

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.

M. Pericak-Vance, A. Roses, C. Warner, 1993, Science.

Missense variants in AIMP1 gene are implicated in autosomal recessive intellectual disability without neurodegeneration

L. Vissers, R. Pfundt, T. Wienker, 2015, European Journal of Human Genetics.

Linkage of scapuloperoneal spinal muscular atrophy to chromosome 12q24.1-q24.31.

M. Pericak-Vance, W. Hung, T. Siddique, 1996, Human molecular genetics.

Detection of Exon 12 and 14 Mutations in Janus Kinase 2 Gene Including a Novel Mutant in V617F Negative Polycythemia Vera Patients from Pakistan

Z. Iqbal, M. Sabar, H. Kausar, 2018, Journal of Cancer.

Detection of BCR-ABL kinase domain mutations in CD34 + cells from newly diagnosed chronic phase CML patients and their association with imatinib resistance

Z. Iqbal, M. Iqbal, S. Baig, 2011 .

Association analysis between four vitamin D receptor gene polymorphisms and developmental dysplasia of the hip

Z. Iqbal, A. Nasr, A. Mashhour, 2018, Journal of Genetics.

Identification of the Risk Factors Associated with Helicobacter pylori Infection in Lahore, Pakistan

Z. Iqbal, A. Basit, M. Ahmad, 2017 .

A Novel Nonsense Variant in GRM1 Causes Autosomal Recessive Spinocerebellar Ataxia 13 in a Consanguineous Pakistani Family

Z. Iqbal, M. Toft, A. Fatima, 2022, Genes.

Impact of Sickle Cell Anemia on children growth and clinical parameters in Al-Ahsa region of Saudi Arabia

Z. Iqbal, Khaled Aljarrah, N. Alanazi, 2021 .

Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells

Z. Iqbal, M. Kassem, M. Elsafadi, 2016, Stem cells international.

University of Southern Denmark Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells

Z. Iqbal, M. Kassem, M. Elsafadi, 2016 .

Prognostically significant fusion oncogenes in Pakistani patients with adult acute lymphoblastic leukemia and their association with disease biology and outcome.

S. Basit, Z. Iqbal, M. Sabar, 2012, Asian Pacific journal of cancer prevention : APJCP.

Frequency of BCR-ABL fusion oncogene in Pakistani childhood acute lymphoid leukemia (ALL) patients reflects ethnic differences in molecular genetics of ALL.

Z. Iqbal, M. Iqbal, Tanveer Akhter, 2007, Journal of pediatric hematology/oncology.

Current view from Alzheimer disease to type 2 diabetes mellitus.

M. Kamal, Z. Iqbal, A. Qazi, 2014, CNS & neurological disorders drug targets.

Molecular Hematology in Leukemia Biology and Treatment: Past, Present, and Future

Z. Iqbal, 2012 .

Genetic elucidation of autosomal recessive intellectual disability

Z. Iqbal, 2013 .

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.

Valter Tucci, Angelo Bifone, Alessandro Gozzi, 2014, The Journal of clinical investigation.

Novel UCHL1 mutations reveal new insights into ubiquitin processing

Z. Iqbal, M. Bjørås, G. Slupphaug, 2016, Human molecular genetics.

Novel UCHL1 mutations reveal new insights into ubiquitin processing.

Z. Iqbal, M. Bjørås, G. Slupphaug, 2017, Human molecular genetics.

Molecular, Cytogenetic, and Hematological Analysis of Chronic Myeloid Leukemia Patients and Discovery of Two Novel Translocations

Z. Iqbal, M. Rasool, Abrar Hussain, 2021, Analytical cellular pathology.

Detection of BCR/ABL Fusion Gene by Hematological and Cytogenetical Analysis in Chronic Myeloid Leukemia Patients in Quetta, Pakistan.

Z. Iqbal, A. Malik, M. Rasool, 2015, Asian Pacific journal of cancer prevention : APJCP.

De novo mutations in PLXND1 and REV3L cause Möbius syndrome

A. Hoischen, N. de Wind, D. Schubert, 2015, Nature Communications.

Exome sequencing of Pakistani consanguineous families identifies 30 novel candidate genes for recessive intellectual disability

D. Grozeva, J. Veltman, T. O’Connor, 2016, Molecular Psychiatry.

Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders.

Christian Gilissen, Bonnie Nijhof, Annette Schenck, 2013, Human molecular genetics.

neurodevelopmental and psychiatric disorders

L. Vissers, H. Peeters, J. Veltman, 2013 .

Mutations in PIGU Impair the Function of the GPI Transamidase Complex, Causing Severe Intellectual Disability, Epilepsy, and Brain Anomalies.

D. Horn, Alexej Knaus, F. Kortüm, 2019, American journal of human genetics.

Sensitive Detection of Pre-Existing BCR-ABL Kinase Domain Mutations in CD34+ Cells of Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Patients Is Associated with Imatinib Resistance: Implications in the Post-Imatinib Era

Mahmood Rasool, Amer Mahmood, Zafar Iqbal, 2013, PloS one.

Case study of primary imatinib resistance and correlation of BCR-ABL multiple mutations in chronic myeloid leukemia

Z. Iqbal, R. Siddiqui, A. Khalid, 2004 .

CA 15-3 (Mucin-1) and physiological characteristics of breast cancer from Lahore, Pakistan.

Z. Iqbal, Sajjad Karim, A. Abuzenadah, 2012, Asian Pacific journal of cancer prevention : APJCP.

Frequency of Bcr-Abl Fusion Oncogene Splice Variants Associated with Chronic Myeloid Leukemia (CML)

Z. Iqbal, M. Iqbal, N. Sheikh, 2011 .

A comprehensive analysis of breakpoint cluster region-abelson fusion oncogene splice variants in chronic myeloid leukemia and their correlation with disease biology

Z. Iqbal, 2014, Indian journal of human genetics.

Homozygous Truncating Variants in TBC1D23 Cause Pontocerebellar Hypoplasia and Alter Cortical Development.

Frédéric Tran Mau-Them, Jean-François Deleuze, Elise Schaefer, 2017, American journal of human genetics.

Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression

Z. Aziz, Z. Iqbal, M. Sabar, 2017, Cancer biology & therapy.

Distinct gene mutations, their prognostic relevance and molecularly targeted therapies in Acute Myeloid Leukemia (AML)

Z. Iqbal, M. Tayyab, S. Altaf, 2014 .

ASSOCIATION OF GENETIC AND NON-GENETIC RISK FACTORS WITH SPECIFIC BRCA MUTATION POSITIVE BREAST CANCERS IN SOME PAKISTANI FEMALES

Z. Iqbal, Sobia Rana, Mohammad Imran, 2009 .

A role of FLT 3 gene mutation in acute myeloid leukemia patients from Pakistan

Z. Iqbal, A. Tanveer, R. Muhammad, 2015 .

Discovery and Protein Modeling Studies of Novel Compound Mutations Causing Resistance to Multiple Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Z. Iqbal, M. Sabar, M. Iqbal, 2020, Asian Pacific journal of cancer prevention : APJCP.

RUNX1 mutation and elevated FLT3 gene expression cooperates to induce inferior prognosis in cytogenetically normal acute myeloid leukemia patients

Walaa F. Alsanie, Z. Iqbal, Zuhair M. Mohammedsaleh, 2021, Saudi journal of biological sciences.

Targeted high throughput sequencing in hereditary ataxia and spastic paraplegia

Zafar Iqbal, Lasse Pihlstrøm, Mathias Toft, 2017, PloS one.

Immunological evaluation of β-thalassemia major patients receiving oral iron chelator deferasirox.

Z. Iqbal, Z. Shakoor, K. AlSaleh, 2014, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

Molecular genetic studies on 167 pediatric ALL patients from different areas of Pakistan confirm a low frequency of the favorable prognosis fusion oncogene TEL-AML1 (t 12; 21) in underdeveloped countries of the region.

Z. Iqbal, 2014, Asian Pacific journal of cancer prevention : APJCP.

Molecular Genetic Studies on 167 Pediatric ALL Patients from Different Areas of Pakistan Confirm a Low Frequency of the Favorable Prognosis Fusion Oncogene TEL-AML1

Z. Iqbal, 2014 .

A de novo microdeletion in NRXN1 in a Dutch patient with mild intellectual disability, microcephaly and gonadal dysgenesis.

R. Pfundt, Z. Iqbal, T. Kleefstra, 2015, Genetics research.

A novel homozygous 10 nucleotide deletion in BBS10 causes Bardet-Biedl syndrome in a Pakistani family.

L. Hoefsloot, Z. Iqbal, H. van Bokhoven, 2013, Gene.

Z. Iqbal, M. Sabar, M. Iqbal, 2015, Molecular Diagnosis & Therapy.

Whole exome sequencing identification of a novel insertion mutation in the phospholipase C ε‑1 gene in a family with steroid resistant inherited nephrotic syndrome.

S. Basit, Z. Iqbal, Sibtain Afzal, 2018, Molecular Medicine Reports.

MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3.

Z. Iqbal, M. Kassem, N. Alajez, 2017, Stem cell research.

Syddansk Universitet MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP 3

Z. Iqbal, M. Kassem, N. Alajez, 2017 .

Awareness of Asthma Genetics in Pakistan: A Review with Some Recommendations

Z. Iqbal, M. U. Ghani, M. Sabar, 2018 .

Sequence variants on 17q21 are associated with the susceptibility of asthma in the population of Lahore, Pakistan

Z. Iqbal, M. U. Ghani, M. Sabar, 2015, The Journal of asthma : official journal of the Association for the Care of Asthma.

BAD, a Proapoptotic Protein, Escapes ERK/RSK Phosphorylation in Deguelin and siRNA-Treated HeLa Cells

Peter Natesan Pushparaj, Z. Iqbal, G. Waris, 2016, PloS one.

Frequency, clinical pattern and outcome of thrombosis in cancer patients in Saudi Arabia.

Z. Iqbal, K. AlSaleh, A. Aleem, 2012, Asian Pacific journal of cancer prevention : APJCP.

Transcriptomics study of neurodegenerative disease: emphasis on synaptic dysfunction mechanism in Alzheimer's disease.

S. S. Sohrab, M. Kamal, Z. Iqbal, 2014, CNS & neurological disorders drug targets.

A complex microcephaly syndrome in a Pakistani family associated with a novel missense mutation in RBBP8 and a heterozygous deletion in NRXN1.

N. de Leeuw, Z. Iqbal, T. Kleefstra, 2014, Gene.

A compound heterozygous mutation in DPAGT1 results in a congenital disorder of glycosylation with a relatively mild phenotype

L. Vissers, J. Veltman, C. Gilissen, 2012, European Journal of Human Genetics.

New possibilities in hepatocellular carcinoma treatment.

M. Kamal, Z. Iqbal, M. Qazi, 2014, Anticancer research.

Integrated Genomic Analysis Identifies ANKRD36 Gene as a Novel and Common Biomarker of Disease Progression in Chronic Myeloid Leukemia

S. Basit, Z. Iqbal, M. Sabar, 2021, Biology.

A novel deletion mutation in proteoglycan-4 underlies camptodactyly-arthropathy-coxa-vara-pericarditis syndrome in a consanguineous pakistani family.

S. Basit, M. Coenen, Z. Iqbal, 2011, Archives of medical research.

Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay

D. Misceo, S. Antonarakis, S. Riazuddin, 2018, Genetics in Medicine.

Loss of function of SVBP leads to autosomal recessive intellectual disability, microcephaly, ataxia, and hypotonia

H. Bokhoven, S. Riazuddin, Z. Iqbal, 2019, Genetics in Medicine.

THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder.

N. Brown, S. Ellard, M. Broly, 2022, American journal of human genetics.

First report of coexistence of sickle cell disease and neurofibromatosis Type 1 in a Saudi patient with family history of neurofibromatosis Type 1

Z. Iqbal, Z. Almoosa, N. Alanazi, 2019, Journal of Applied Hematology.

TMEM230 variants in Parkinson’s disease

Z. Iqbal, M. Toft, 2019, Nature Genetics.

Eltrombopag for tyrosine kinase inhibitors-associated thrombocytopenia in chronic myeloid leukemia

Z. Iqbal, G. Alotaibi, A. Aleem, 2023, International journal of hematology.

Global Expression Studies of Schizophrenic Brain: A Meta-Analysis Study Linking Neurological Immune System with Psychological Disorders.

M. Kamal, Z. Iqbal, Sajjad Karim, 2016, CNS & neurological disorders drug targets.

Missense mutations in DYT-TOR1A dystonia

I. Skogseid, Z. Iqbal, M. Toft, 2019, Neurology: Genetics.

Vitamin D and Gastric Cancer: A Ray of Sunshine?

Z. Iqbal, N. Soni, S. Yadav, 2021, Cureus.

rs12603332 is associated with male asthma patients specifically in urban areas of Lahore, Pakistan

Z. Iqbal, M. U. Ghani, M. Sabar, 2017, The Journal of asthma : official journal of the Association for the Care of Asthma.

Investigations on Novel Gene Variants Associated with Longterm Response to Tyrosine Kinase Inhibitors (TKIs) in Chronic Myeloid Leukemia: Implication in TKI-Cessation Clinical Trails

S. Basit, Z. Iqbal, M. Sabar, 2019, Blood.

Global Expression Studies of Schizophrenic Brain: A Meta-Analysis Study Linking Neurological Immune System with Psychological Disorders

Z. Iqbal, Sajjad Karim, M. Rasool, 2016 .