H. Christian

发表

Presynaptic NMDARs in the Hippocampus Facilitate Transmitter Release at Theta Frequency

P. Donnelly, C. Yau, N. Emptage, 2010, Neuron.

Non-classical actions of testosterone: an update

H. Christian, F. Rahman, 2007, Trends in Endocrinology & Metabolism.

Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice.

I. Robinson, H. Christian, J. Phillips, 2003, Endocrinology.

Spatially coordinated dynamic gene transcription in living pituitary tissue

Hiroshi Momiji, Karen Featherstone, Anne V. McNamara, 2015, eLife.

Annexin 1 dependent actions of glucocorticoids in the anterior pituitary gland—role of the formyl peptide receptor family

H. Christian, V. Sahni, E. Solito, 2006, Frontiers in Neuroendocrinology.

Annexin 1 and the regulation of endocrine function

H. Christian, R. Flower, E. Solito, 2004, Trends in Endocrinology & Metabolism.

Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system

H. Christian, R. Flower, E. Solito, 2003, Cell biochemistry and function.

Nongenomic actions of testosterone on a subset of lactotrophs in the male rat pituitary.

H. Christian, J. Morris, N. Rolls, 2000, Endocrinology.

Hyperprolactinemia in a male pituitary androgen receptor knockout mouse is associated with female‐like lactotroph development

Lee B. Smith, H. Christian, P. Tissier, 2021, Andrology.

Hyperprolactinemia in a male pituitary androgen receptor knockout mouse model is associated with a female-like pattern of lactotroph development

Lee B. Smith, H. Christian, P. L. Le Tissier, 2020, bioRxiv.

Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female, but not male, rats.

H. Christian, J. Morris, G. Gillies, 2006, Endocrinology.

Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.

H. Christian, P. Tynan, C. Diéguez, 2015, Endocrinology.

Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion

H. Christian, 2020, Neurosecretion: Secretory Mechanisms.

Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications

E. Maggioli, H. Christian, P. Couraud, 2012, Proceedings of the National Academy of Sciences.

S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation.

Sean M. Hartig, X. Zhang, P. Saha, 2019, JCI insight.

ventilatory sensitivity to hypoxia causes carotid-body hyperplasia and enhanced The von Hippel-Lindau Chuvash mutation in mice

H. Christian, Philip J. Turner, K. Buckler, 2015 .

The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia

P. Robbins, H. Christian, Philip J. Turner, 2013, Journal of applied physiology.

Folliculo-stellate Cells: Paracrine Communicators in the Anterior Pituitary

H. Christian, J. Morris, 2011 .

Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.

C. Kahn, H. Christian, R. Kineman, 2013, Endocrinology.

MC‐3 receptor and the inflammatory mechanisms activated in acute myocardial infarct

H. Christian, M. Perretti, F. Rossi, 2004, Journal of leukocyte biology.

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis

K. Clarke, P. Robbins, H. Christian, 2016, eLife.

Lack of Fpr2/Fpr3 receptors alters the structure and function of pituitary corticotrophs

H. Christian, M. Mahmood, 2014 .

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell‐Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

M. Turner, G. Weir, Tatjana Lalic, 2016, Stem cells.

Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue.

H. Christian, R. Flower, D. Sugden, 2006, American journal of physiology. Endocrinology and metabolism.

Different degrees of somatotroph ablation compromise pituitary growth hormone cell network structure and other pituitary endocrine cell types.

I. Robinson, H. Christian, P. L. Le Tissier, 2010, Endocrinology.

Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells − implication for placental cell fusion

I. Sargent, H. Christian, C. Redman, 2007, The FEBS journal.

Differential effect of cross-linking the CD98 heavy chain on fusion and amino acid transport in the human placental trophoblast (BeWo) cell line.

I. Sargent, H. Christian, C. Redman, 2007, Biochimica et biophysica acta.

Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1

H. Christian, R. Flower, S. McArthur, 2009, Biochemical pharmacology.

MORPHOLOGICAL ALTERATION OF PERITONEAL MAST CELLS AND MACROPHAGES IN THE MOUSE PERITONEAL CAVITY DURING THE EARLY PHASES OF AN ALLERGIC INFLAMMATORY REACTION

H. Christian, M. Perretti, S. Oliani, 2001, Cell biology international.

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization

H. Christian, R. Flower, S. McArthur, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Correction

Richard J. Stillion, Samira, K. Clarke, 1981, Biofouling.

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function

Richard J. Stillion, K. Clarke, P. Robbins, 2015, Proceedings of the National Academy of Sciences.

hexanucleotide expansions are associated with altered ER calcium homeostasis and stress granule formation in iPSC-derived neurons from patients with amyotrophic lateral sclerosis and frontotemporal dementia

M. Turner, G. Weir, Tatjana Lalic, 2016 .

Activation of the HPA axis by immune insults: Roles and interactions of cytokines, eicosanoids, and glucocorticoids

H. Christian, J. Buckingham, J. Philip, 1996, Pharmacology Biochemistry and Behavior.

Dexamethasone induces rapid serine-phosphorylation and membrane translocation of annexin 1 in a human folliculostellate cell line via a novel nongenomic mechanism involving the glucocorticoid receptor, protein kinase C, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase.

H. Christian, R. Flower, E. Solito, 2003, Endocrinology.

Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target cell-induced acylation

H. Christian, I. Guschina, T. Wells, 2017, Scientific Reports.

The Intermediate lactotroph: a morphologically distinct, ghrelin-responsive pituitary cell in the dwarf (dw/dw) rat.

H. Christian, I. Huerta-ocampo, T. Wells, 2005, Endocrinology.

Evidence from immunoneutralization and antisense studies that the inhibitory actions of glucocorticoids on growth hormone release in vitro require annexin 1 (lipocortin 1)

H. Christian, R. Flower, J. Morris, 2000, British journal of pharmacology.

Expression, subcellular localization and phosphorylation status of annexins 1 and 5 in human pituitary adenomas and a growth hormone‐secreting carcinoma

H. Christian, E. Solito, J. Buckingham, 2004, Clinical endocrinology.

An Immunocytochemical and In Situ Hybridization Analysis of Annexin 1 Expression in Rat Mast Cells: Modulation by Inflammation and Dexamethasone

H. Christian, M. Perretti, R. Flower, 2000, Laboratory Investigation.

A secreted fluorescent reporter targeted to pituitary growth hormone cells in transgenic mice.

I. Robinson, N. Balthasar, H. Christian, 2000, Endocrinology.

An antisense oligodeoxynucleotide to lipocortin 1 reverses the inhibitory actions of dexamethasone on the release of adrenocorticotropin from rat pituitary tissue in vitro.

H. Christian, R. Flower, J. Morris, 1997, Endocrinology.

Characterization and localization of lipocortin 1-binding sites on rat anterior pituitary cells by fluorescence-activated cell analysis/sorting and electron microscopy.

H. Christian, R. Flower, J. Morris, 1997, Endocrinology.

Externalization of annexin I from a folliculo-stellate-like cell line.

H. Christian, J. Buckingham, J. Morris, 2002, Endocrinology.

Lipocortin 1 (Annexin 1): A Candidate Paracrine Agent Localized in Pituitary Folliculo-Stellate Cells1.

H. Christian, J. Buckingham, J. Morris, 1999, Endocrinology.

Lipocortin 1 (Annexin 1): A Candidate Paracrine Agent Localized in Pituitary Folliculo-Stellate Cells1.

H. Christian, J. Morris, J. Buckingham, 1999, Endocrinology.

Steroid Effects on Secretion from Subsets of Lactotrophs: Role of Folliculo-Stellate Cells and Annexin 1

H. Christian, J. Morris, H. Ozawa, 2002, Archives of physiology and biochemistry.

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.

Julian R. E. Davis, D. Berney, R. Quinton, 2008, The Journal of clinical endocrinology and metabolism.

Disentangling juxtacrine from paracrine signalling in dynamic tissue

David A. Rand, Hiroshi Momiji, Kirsty L. Hassall, 2019, PLoS Comput. Biol..

Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration.

Z. Molnár, A. Hoerder-Suabedissen, H. Christian, 2018, Cerebral cortex.

Effects of exogenous and endogenous prostaglandins on the fast phase of contraction of the guinea-pig vas deferens produced by electrical field stimulation.

H. Christian, N. Poyser, 1994, Prostaglandins, leukotrienes, and essential fatty acids.

Annexin A1: A Central Player in the Anti-Inflammatory and Neuroprotective Role of Microglia

H. Christian, F. Roncaroli, G. Gillies, 2010, The Journal of Immunology.

Post‐translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface

H. Christian, R. Flower, E. Solito, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression.

H. Christian, M. Paul-Clark, M. Perretti, 2001, The American journal of pathology.

Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.

H. Christian, S. Camper, P. Gergics, 2016, Endocrinology.

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

H. Christian, K. Talbot, S. Sardi, 2016, Stem cell reports.

Manipulating the in vivo mRNA expression profile of FSH beta to resemble that of LH beta does not promote a concomitant increase in intracellular storage of follicle-stimulating hormone.

H. Christian, M. Walker, J. Evans, 2001 .

Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

H. Christian, J. Drouin, A. Balsalobre, 2019, Nature Communications.

Annexin A1 in the brain--undiscovered roles?

H. Christian, G. Gillies, S. McArthur, 2008, Trends in pharmacological sciences.

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.

Richard Wade-Martins, Helen Christian, Olaf Ansorge, 2009, Human molecular genetics.

Role of Annexin A1 in mouse myoblast cell differentiation

H. Christian, B. Fontanella, A. Petrella, 2010, Journal of cellular physiology.

Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals

Gary R. Mirams, H. Christian, A. Parekh, 2016, Molecular cell.

Characterisation of a mural cell network in the murine pituitary gland

Lee B. Smith, H. Christian, P. L. Le Tissier, 2020, Journal of neuroendocrinology.

Evidence for a role of the adenosine 5'-triphosphate-binding cassette transporter A1 in the externalization of annexin I from pituitary folliculo-stellate cells.

H. Christian, M. Epton, J. Buckingham, 2003, Endocrinology.

The influence of 17β-estradiol on annexin 1 expression in the anterior pituitary of the female rat and in a folliculo-stellate cell line

H. Christian, J. Morris, S. Omer, 2006, The Journal of endocrinology.

Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals

Julian R. E. Davis, A. Loudon, D. Burt, 2015, Current Biology.

Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations.

H. Christian, J. Mullins, C. Macrae, 2017, American journal of physiology. Renal physiology.

Existence of long-lasting experience-dependent plasticity in endocrine cell networks

Helen Christian, David J. Hodson, Patrice Mollard, 2012, Nature Communications.

The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase

H. Christian, D. Meredith, C. Boyd, 2010, American journal of physiology. Gastrointestinal and liver physiology.

The apical ( hPepT 1 ) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase

H. Christian, D. Meredith, C. Boyd, 2010 .

Important Role for Melanocortin 3 Receptor Recessive Yellow ( e / e ) Mouse Suggest an Melanocortin Peptides : Studies in the ofReceptor in the Anti-inflammatory Actions Redundancy of a Functional Melanocortin 1 and Mauro Perretti

H. Schiöth, H. Christian, M. Perretti, 2003 .

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

H. Christian, M. Perretti, R. Flower, 2002, Arthritis and rheumatism.

University of Southern Denmark ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N 370 S Parkinson ' s iPSC-Derived Dopamine Neurons

H. Christian, K. Talbot, S. Sardi, 2022 .

Syddansk Universitet ER Stress and Autophagic Perturbations Lead to Elevated Extracellular-Synuclein in GBA-N 370 S Parkinson ' s iPSC-Derived Dopamine Neurons

H. Christian, K. Talbot, S. Sardi, 2022 .

Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory Actions of Melanocortin Peptides: Studies in the Recessive Yellow (e/e) Mouse Suggest an Important Role for Melanocortin 3 Receptor1

H. Schiöth, H. Christian, M. Perretti, 2003, The Journal of Immunology.

Cell-autonomous transcriptional mechanism for enhancement of translation capacity in secretory cells

H. Christian, J. Drouin, A. Balsalobre, 2018, bioRxiv.

Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function

I. Robinson, S. Charpak, J. Lecoq, 2010, Proceedings of the National Academy of Sciences.

Application of magnetic field hyperthermia and superparamagnetic iron oxide nanoparticles to HIV-1-specific T-cell cytotoxicity

Q. Pankhurst, R. Phillips, A. Sewell, 2013, International journal of nanomedicine.

Perinatal glucocorticoid treatment produces molecular, functional, and morphological changes in the anterior pituitary gland of the adult male rat.

H. Christian, J. Morris, E. Theogaraj, 2005, Endocrinology.

Edinburgh Research Explorer Phenotypic dissection of the mouse Ren-1(d) knockout by complementation with human renin

H. Christian, S. Semprini, J. Mullins, 2018 .

Phenotypic dissection of the mouse Ren1d knockout by complementation with human renin

H. Christian, S. Semprini, J. Mullins, 2017, The Journal of Biological Chemistry.

Dendritic secretion of peptides from hypothalamic magnocellular neurosecretory neurones: a local dynamic control system and its functions

D. Ma, H. Christian, J. Morris, 2000, Experimental physiology.

Annexin 1-dependent actions of glucocorticoids in the anterior pituitary gland: roles of the N-terminal domain and protein kinase C.

H. Christian, R. Flower, E. Solito, 2002, Endocrinology.

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice.

H. Christian, J. Buckingham, J. Morris, 2007, Endocrinology.

Annexin 1, Glucocorticoids, and the Neuroendocrine–Immune Interface

H. Christian, R. Flower, E. Solito, 2006, Annals of the New York Academy of Sciences.

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

Gary R. Mirams, Rebecca A. B. Burton, Kerrie L. Ford, 2017, Scientific Reports.

Evidence for the role of adenosine 5'-triphosphate-binding cassette (ABC)-A1 in the externalization of annexin 1 from pituitary folliculostellate cells and ABCA1-transfected cell models.

H. Christian, D. Meredith, J. Morris, 2006, Endocrinology.

Human kidney pericytes produce renin

H. Christian, J. Mullins, A. Stefańska, 2016, Kidney international.

OPEN Human kidney pericytes produce renin

H. Christian, J. Mullins, A. Stefańska, 2016 .

Explorer Human kidney pericytes produce renin

H. Christian, J. Mullins, A. Stefańska, 2016 .

The SLC16 monocaboxylate transporter family.

H. Christian, D. Meredith, 2008, Xenobiotica; the fate of foreign compounds in biological systems.

The Role of NAADP-Mediated Endo-Lysosomal Calcium Release in the Cardiac Atria

Rebecca A. B. Burton, A. Galione, H. Christian, 2020 .

Transgenesis and neuroendocrine physiology: a transgenic rat model expressing growth hormone in vasopressin neurones

I. Robinson, H. Christian, D. Flavell, 2003, The Journal of physiology.

Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells.

H. Christian, S. Williams, P. Grasa, 2015, Developmental biology.

The annexin 1-/- mouse: phenotypic studies

H. Christian, M. Paul-Clark, R. Hannon, 2004 .

d-amino acid-substituted analogs of corticotropin-releasing hormone (CRH) and urocortin with selective agonist activity at CRH1 and CRH2β receptors

H. Christian, J. Buckingham, E. Wei, 1998, Peptides.

D-amino acid-substituted analogs of corticotropin-releasing hormone (CRH) and urocortin with selective agonist activity at CRH1 and CRH2beta receptors.

H. Christian, J. Buckingham, E. Wei, 1998, Peptides.

Circadian clock mechanism driving mammalian photoperiodism

A. Loudon, D. Burt, D. Burt, 2020, Nature Communications.

Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.

H. Christian, P. Tynan, C. Diéguez, 2015, Endocrinology.

Annexin A1 in the brain--undiscovered roles?

H. Christian, G. Gillies, S. McArthur, 2008, Trends in pharmacological sciences.

Dissociation of nitric oxide synthase immunoreactivity and NADPH-diaphorase enzyme activity in rat pituitary.

H. Christian, J. Morris, H. Wang, 1997, Journal of Endocrinology.