R. Reid

发表

Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.

Sarah J Kodumal, Kedar G. Patel, R. Reid, 2004, Proceedings of the National Academy of Sciences of the United States of America.

GeMS: an advanced software package for designing synthetic genes

R. Reid, D. Santi, Sebastian Jayaraj, 2005, Nucleic acids research.

Chalcomycin Biosynthesis Gene Cluster from Streptomyces bikiniensis: Novel Features of an Unusual Ketolide Produced through Expression of the chm Polyketide Synthase in Streptomyces fradiae

R. Reid, A. Schirmer, L. Katz, 2004, Antimicrobial Agents and Chemotherapy.

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.

C Richard Hutchinson, R. Reid, D. Santi, 2003, Biochemistry.

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes

John R Carney, Kedar G. Patel, R. Reid, 2005, Nature Biotechnology.

PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89

H. VanBrocklin, R. Reid, D. Santi, 2019, Molecular Cancer Therapeutics.

Hydrogel drug delivery system with predictable and tunable drug release and degradation rates

R. Reid, D. Santi, G. Ashley, 2013, Proceedings of the National Academy of Sciences.

Elucidating the mechanism of cis double bond formation in epothilone biosynthesis.

L. Chung, R. Reid, J. Carney, 2004, Journal of the American Chemical Society.

Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft

B. Hann, R. Reid, D. Santi, 2019, Cancer Chemotherapy and Pharmacology.

PLX038: a PEGylated prodrug of SN-38 independent of UGT1A1 activity

R. Reid, D. Santi, G. Ashley, 2019, Cancer Chemotherapy and Pharmacology.

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

R. Reid, D. Santi, G. Ashley, 2018, Translational vision science & technology.

Genes for the Biosynthesis of the Fungal Polyketides Hypothemycin from Hypomyces subiculosus and Radicicol from Pochonia chlamydosporia

R. Reid, J. Kealey, Zhihao Hu, 2008, Applied and Environmental Microbiology.

Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates

R. Reid, D. Santi, G. Ashley, 2012, Proceedings of the National Academy of Sciences.

Molecular modeling and crystal structure of ERK2-hypothemycin complexes.

Giulio Rastelli, G. Rastelli, R. Rosenfeld, 2008, Journal of structural biology.

Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.

R. Reid, D. Santi, J. Kennedy, 2006, Proceedings of the National Academy of Sciences of the United States of America.

A new enzyme superfamily - the phosphopantetheinyl transferases.

M. Marahiel, C. Walsh, C. Khosla, 1996, Chemistry & biology.

β-Eliminative releasable linkers adapted for bioconjugation of macromolecules to phenols.

R. Reid, D. Santi, G. Ashley, 2013, Bioconjugate chemistry.

Long-term stabilization of maleimide-thiol conjugates.

Louise Robinson, R. Reid, D. Santi, 2015, Bioconjugate chemistry.

Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

Andreas Schirmer, Zhihao Hu, C Richard Hutchinson, 2003, FEMS microbiology letters.

A long-acting C-natriuretic peptide for achondroplasia

R. Reid, D. Santi, G. Ashley, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Insights into the Biosynthesis of the Benzoquinone Ansamycins Geldanamycin and Herbimycin, Obtained by Gene Sequencing and Disruption

C. Richard Hutchinson, Zhihao Hu, R. Reid, 2005, Applied and Environmental Microbiology.

The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation.

R. Reid, H. Gramajo, N. Viswanathan, 2005, Gene.

A very long-acting IL-15: implications for the immunotherapy of cancer

John A. Hangasky, T. Waldmann, R. Reid, 2022, Journal for ImmunoTherapy of Cancer.

Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.

R. Reid, C. Reeves, B. Julien, 2006, Chemistry & biology.

Subcutaneously Administered Self-Cleaving Hydrogel-Octreotide Conjugates Provide Very Long-Acting Octreotide.

R. Reid, D. Santi, G. Ashley, 2016, Bioconjugate chemistry.

Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake.

S. Pfaff, R. Reid, D. Santi, 2016, Bioconjugate chemistry.

A Hydrogel-Microsphere Drug Delivery System That Supports Once-Monthly Administration of a GLP-1 Receptor Agonist.

S. Pfaff, N. Vrang, R. Reid, 2017, ACS chemical biology.

Hydrogel Drug Delivery System Using Self-Cleaving Covalent Linkers for Once-a-Week Administration of Exenatide.

R. Reid, D. Santi, G. Ashley, 2016, Bioconjugate chemistry.

The Leptomycin Gene Cluster and Its Heterologous Expression in Streptomyces lividans

R. Reid, H. Gramajo, Zhihao Hu, 2005, The Journal of Antibiotics.

Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster

R. Reid, M. Welch, D. Santi, 2005, Journal of Industrial Microbiology and Biotechnology.

Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System

A. Sali, M. Sgobba, G. Rastelli, 2015 .

A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors

R. Reid, G. Ashley, Shaun D. Fontaine, 2023, Cancer research communications.