C. Endres

发表

Initial Evaluation of 11C-DPA-713, a Novel TSPO PET Ligand, in Humans

M. Pomper, D. Hammoud, R. Dannals, 2009, Journal of Nuclear Medicine.

Generalized inter-frame and intra-frame motion correction in PET imaging - a simulation study

Dean F. Wong, Arman Rahmim, Hassan Mohy-ud-Din, 2011, 2011 IEEE Nuclear Science Symposium Conference Record.

Molecular Imaging of Conscious, Unrestrained Mice with AwakeSPECT

J. Goddard, M. Pomper, C. Endres, 2013, The Journal of Nuclear Medicine.

Kinetic Modeling of [11C]Raclopride: Combined PET-Microdialysis Studies

W C Eckelman, R E Carson, R. Saunders, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Decreased microglial activation in MS patients treated with glatiramer acetate

Peter A. Calabresi, Navid Shiee, Dzung L. Pham, 2012, Journal of Neurology.

Characteristics of Neurotransmitter Competition Studies Using Constant Infusion of Tracer

R. Carson, C. Endres, 1998 .

Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV

Jennifer M. Coughlin, B. Caffo, B. Caffo, 2014, Journal of NeuroVirology.

Radiation Dosimetry and Biodistribution of the TSPO Ligand 11C-DPA-713 in Humans

Jennifer M. Coughlin, M. Pomper, K. Gage, 2012, Journal of Nuclear Medicine.

Imaging of Musculoskeletal Bacterial Infections by [124I]FIAU-PET/CT

K. Kinzler, C. Bettegowda, B. Vogelstein, 2007, PloS one.

Residues Met89 and Ser160 in the Human Equilibrative Nucleoside Transporter 1 Affect Its Affinity for Adenosine, Guanosine, S6-(4-Nitrobenzyl)-mercaptopurine Riboside, and Dipyridamole

C. Endres, J. Unadkat, 2005, Molecular Pharmacology.

Sensitivity of kinetic macro parameters to changes in dopamine synthesis, storage, and metabolism: A simulation study for [18F]FDOPA PET by a model with detailed dopamine pathway

Takuya Hayashi, H. Watabe, H. Iida, 2011, Synapse.

The Impact and In Vitro to In Vivo Prediction of Transporter-Based Drug–Drug Interactions in Humans

C. Endres, J. Zolnerciks, J. Unadkat, 2010 .

Affinities of dopamine analogs for monoamine granular and plasma membrane transporters: implications for PET dopamine studies.

J E Holden, J. Holden, O. DeJesus, 1997, Life sciences.

Time profile of cerebral [18F]6-fluoro-L-DOPA metabolites in nonhuman primate: implications for the kinetics of therapeutic L-DOPA.

J. Holden, D. Doudet, H. Uno, 2004, Frontiers in bioscience : a journal and virtual library.

Modeling of PET / SPECT Receptor Images

R. Fisher, B. Christian, E. Morris, 2022 .

Reference tissue modeling with parameter coupling: application to a study of SERT binding in HIV.

M. Pomper, D. Hammoud, C. Endres, 2011, Physics in medicine and biology.

Brain Mu-Opioid Receptor Binding Predicts Treatment Outcome in Cocaine-Abusing Outpatients

U. Ghitza, D. Epstein, K. Preston, 2010, Biological Psychiatry.

Population Pharmacokinetic Modeling and Exposure–Response Assessment for the Antibody‐Drug Conjugate Brentuximab Vedotin in Hodgkin's Lymphoma in the Phase III ECHELON‐1 Study

K. Venkatakrishnan, D. Mould, C. Endres, 2019, Clinical pharmacology and therapeutics.

The Role of Nucleoside Transporters in the Erythrocyte Disposition and Oral Absorption of Ribavirin in the Wild-Type and Equilibrative Nucleoside Transporter 1(−/−) Mice

C. Endres, J. Unadkat, D. Choi, 2009, Journal of Pharmacology and Experimental Therapeutics.

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.

C. Endres, D. Whittington, C. Tse, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects

C. Endres, S. Alley, Anthony J. Lee, 2020, Journal of clinical pharmacology.

Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography

Jennifer M. Coughlin, M. Petri, M. Pomper, 2017, Lupus.

The role of the equilibrative nucleoside transporter 1 on tissue and fetal distribution of ribavirin in the mouse

C. Endres, J. Unadkat, Rajgopal Govindarajan, 2016, Biopharmaceutics & drug disposition.

Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS

T. Guilarte, M. Pomper, D. Wong, 2005, Journal of NeuroVirology.

Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl

L. Wienkers, C. Endres, S. Alley, 2022, Cancer Chemotherapy and Pharmacology.

Population pharmacokinetics of brodalumab in healthy adults and adults with psoriasis from single and multiple dose studies

D. Salinger, C. Endres, M. Gibbs, 2014, Journal of clinical pharmacology.

Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

C. Endres, D. Sengupta, J. Unadkat, 2004, The Biochemical journal.

Evaluation of fluorinated m-tyrosine analogs as PET imaging agents of dopamine nerve terminals: comparison with 6-fluoroDOPA.

S. Shelton, J. Holden, O. DeJesus, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

(hENT1) Affect hENT1’s Affinity for Adenosine, Guanosine, NBMPR and Dipyridamole

C. Endres, J. Unadkat, 2004 .

Evaluation of Safety and Clinically Relevant Drug–Drug Interactions with Tucatinib in Healthy Volunteers

C. Endres, L. Walker, Anthony Lee, 2022, Clinical Pharmacokinetics.

Single Photon Emission Computed Tomography (SPECT) Experience with (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-[123I]IA) in the Living Human Brain of Smokers and Nonsmokers

D. Wong, C. Endres, J. Hilton, 2011 .

A New Linear Parametric Imaging Algorithm Derived from a Simplified Reference Tissue Model for Ligand-Receptor Dynamic PET Studies

Yun Zhou, Sung-Cheng Huang, Sung-Cheng Huang, 2002 .

Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.

D. Holt, D. Wong, A. Horti, 2007, Journal of medicinal chemistry.

Measurement of dopamine release with continuous infusion of [11C]raclopride: optimization and signal-to-noise considerations.

W C Eckelman, R E Carson, H Watabe, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Linear regression with spatial constraint to generate parametric images of ligand-receptor dynamic PET studies with a simplified reference tissue model

Sung-Cheng Huang, Yun Zhou, Christopher J Endres, 2003, NeuroImage.

In vivo muscarinic binding selectivity of (R,S)- and (R,R)-[18F]-fluoromethyl QNB.

P. Herscovitch, R. Carson, C. Endres, 1997, Bioorganic & medicinal chemistry.

Biodistribution, Tumor Detection, and Radiation Dosimetry of 18F-DCFBC, a Low-Molecular-Weight Inhibitor of Prostate-Specific Membrane Antigen, in Patients with Metastatic Prostate Cancer

George Sgouros, Martin Lodge, Daniel P. Holt, 2012, The Journal of Nuclear Medicine.

The role of transporters in drug interactions.

Christopher J Endres, Jashvant D Unadkat, C. Endres, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Fluorodeoxyglucose Positron Emission Tomography Correlates With Akt Pathway Activity but Is Not Predictive of Clinical Outcome During mTOR Inhibitor Therapy

R. Wahl, A. Jimeno, M. Hidalgo, 2009 .

The Pharmacokinetics and Safety of Tucatinib in Volunteers with Hepatic Impairment

C. Endres, Anthony J. Lee, L. Walker, 2022, Clinical pharmacokinetics.

The Role of the Equilibrative Nucleoside Transporter 1 (ENT1) in Transport and Metabolism of Ribavirin by Human and Wild-Type or Ent1(-/-) Mouse Erythrocytes

C. Endres, J. Unadkat, D. Choi, 2009, Journal of Pharmacology and Experimental Therapeutics.

Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies

D. Salinger, C. Endres, E. Hurh, 2011, Clinical pharmacokinetics.

PET imaging of brain acetylcholinesterase using [11C]CP‐126,998, a brain selective enzyme inhibitor

R. Dannals, C. Endres, J. Hilton, 2002, Synapse.

Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: an agonist probe for the α7 nicotinic acetylcholine receptor.

M. Pomper, D. Holt, R. Dannals, 2013, Nuclear medicine and biology.

Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2).

A. Savonenko, D. Wong, A. Horti, 2010, Bioorganic & medicinal chemistry.

Role of the equilibrative and concentrative nucleoside transporters in the intestinal absorption of the nucleoside drug, ribavirin, in wild-type and Ent1(-/-) mice.

C. Endres, J. Unadkat, D. Choi, 2012, Molecular pharmaceutics.

Noradrenergic and dopaminergic effects of (+)‐amphetamine‐like stimulants in the baboon Papio anubis

Christopher J Endres, James Robert Brašić, Dean F Wong, 2005, Synapse.

Functional neuroimaging in child psychiatry: Modeling of receptor images in PET and SPECT

R. Fisher, E. Morris, R. F. Muzic, 2000 .

Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.

D. Holt, D. Wong, A. Horti, 2009, Bioorganic & medicinal chemistry.

Single photon emission computed tomography experience with (S)‐5‐[123I]iodo‐3‐(2‐azetidinylmethoxy)pyridine in the living human brain of smokers and nonsmokers

Yun Zhou, John Hilton, Christopher J Endres, 2009, Synapse.

Sex Differences in Translocator Protein 18 kDa (TSPO) in the Heart: Implications for Imaging Myocardial Inflammation

T. Guilarte, L. Cooper, M. Pomper, 2014, Journal of Cardiovascular Translational Research.

Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy

Jennifer M. Coughlin, M. Pomper, C. Endres, 2018, AIDS.

Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV

Jennifer M. Coughlin, B. Caffo, T. Guilarte, 2014, Journal of NeuroVirology.

Imaging serotonergic transmission with [11C]DASB-PET in depressed and non-depressed patients infected with HIV

Martin Gilbert Pomper, Adam I. Kaplin, Dima A. Hammoud, 2010, NeuroImage.

Graphical analysis of 6-fluoro-L-dopa trapping: effect of inhibition of catechol-O-methyltransferase.

V Sossi, J E Holden, V. Sossi, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

An extended simplified reference tissue model for the quantification of dynamic PET with amphetamine challenge

Yun Zhou, Dean F. Wong, Weiguo Ye, 2006, NeuroImage.

A semi‐mechanistic model to characterize the pharmacokinetics and pharmacodynamics of brodalumab in healthy volunteers and subjects with psoriasis in a first‐in‐human single ascending dose study

D. Salinger, C. Endres, M. Gibbs, 2014, Clinical pharmacology in drug development.

Novel parametric PET image quantification using texture and shape analysis

A. Rahmim, J. Coughlin, M. Gonzalez, 2012, 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC).

Assessment of Dynamic Neurotransmitter Changes with Bolus or Infusion Delivery of Neuroreceptor Ligands

R E Carson, C. Endres, C J Endres, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Electrophysiological Characterization and Modeling of the Structure Activity Relationship of the Human Concentrative Nucleoside Transporter 3 (hCNT3)

P. Swaan, C. Endres, V. Ganapathy, 2006, Molecular Pharmacology.

Quantification of brain mu-opioid receptors with [11C]carfentanil: reference-tissue methods.

Badreddine Bencherif, Igal Madar, John Hilton, 2003, Nuclear medicine and biology.

Noninvasive assessment of aromatic L‐amino acid decarboxylase activity in aging rhesus monkey brain in vivo

S. Shelton, J. Holden, O. DeJesus, 2001, Synapse.

Human [/sup 123/I]5-I-A-85380 dynamic SPECT studies in normals: kinetic analysis and parametric imaging

John L. Musachio, Hiroto Kuwabara, Yun Zhou, 2001, 2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310).

Interplay of drug metabolism and transport: a real phenomenon or an artifact of the site of measurement?

Christopher J. Endres, Michael G. Endres, Jashvant D. Unadkat, 2009, Molecular pharmaceutics.

Modeling Methods for the Determination of Dopamine Release with [11C]Raclopride and Constant Infusion

C. J. Endres, H. Watabe, R. E. Carson, 1998, NeuroImage.

Risk‐Based Pharmacokinetic and Drug–Drug Interaction Characterization of Antibody–Drug Conjugates in Oncology Clinical Development: An International Consortium for Innovation and Quality in Pharmaceutical Development Perspective

C. Endres, K. Liao, M. Walles, 2021, Clinical pharmacology and therapeutics.

Brain Mu-Opioid Receptor Binding Predicts Treatment Outcome in Cocaine-Abusing Outpatients

Udi E. Ghitza, D. Epstein, K. Preston, 2010, Biological Psychiatry.

Changes in FDG-PET in response to rapamycin (R) correlated with Akt pathway inhibition and not with clinical outcome

A. Jimeno, M. Hidalgo, M. Pomper, 2008 .