P. Renard

O. Diouf, P. Renard, B. Masereel, 1998, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis and Biological Evaluation of New 3‐Aralkylamino‐2‐aryl‐2H‐1,2,4‐pyridothiadiazine 1,1‐dioxides as Potential CCK‐Receptor Ligands

P. Tullio, O. Diouf, P. Renard, 1997, The Journal of pharmacy and pharmacology.

Synthesis and Cytotoxic Activity of Benzopyranoxanthone Analogues of Benzo[b]acronycine and Psorospermine

P. Renard, B. Pfeiffer, F. Tillequin, 2001 .

A convenient extension of the Wessely-Moser rearrangement for the synthesis of substituted alkylaminoflavones as neuroprotective agents in vitro.

P. Renard, B. Lockhart, M. Largeron, 2000, Bioorganic & medicinal chemistry letters.

Complex bases promoted arynic cyclisations of halogenated imines or enamines: A regiochemical synthesis of indole derivatives

P. Renard, B. Jamart-Grégoire, P. Caubére, 1993 .

Cytotoxic activities of novel hexahydroindolizino[8,7-b]indole derivatives prepared by 1,3-dipolar cycloaddition reactions of 3,4-dihydro-beta-carboline ylides.

P. Renard, B. Pfeiffer, G. Werner, 2001, Bioorganic & medicinal chemistry.

Synthesis of tetracyclic dioxygenated isoquinolines and their cytotoxic activity

P. Renard, D. Caignard, M. D. Pujol, 2008 .

Synthesis of isoquinolines and tetrahydroisoquinolines as potential antitumour agents

P. Renard, M. D. Pujol, D. Caignard, 2001 .

Aryldithioethyloxycarbonyl (Ardec): a new family of amine protecting groups removable under mild reducing conditions and their applications to peptide synthesis.

A. Romieu, G. Turcatti, H. Vaudry, 2006, Chemistry.

Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series.

P. Renard, A. Skaltsounis, P. Magiatis, 1998, Journal of Natural Products.

Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.

P. Renard, M. Rettori, B. Pfeiffer, 2003, Journal of medicinal chemistry.

Synthetic Route to Rare Isoindolones Derivatives

P. Renard, L. Jean, S. Routier, 2015 .

First synthesis and pharmacological evaluation of benzoindolizidine and benzoquinolizidine analogues of α- and β-peltatin

Eric Deniau, Pierre Renard, Axel Couture, 2000 .

Synthesis and cytotoxicity of analogues of the antibiotic BE 10988 inhibitors of DNA topoisomerase II.

C. Bailly, P. Renard, B. Pfeiffer, 1999, Bioorganic & medicinal chemistry letters.

Easy access to phosphonothioates.

P. Renard, A. Valleix, C. Mioskowski, 2002, Chemistry.

Easy access to phosphonothioates.

P. Renard, A. Valleix, C. Mioskowski, 2002, Chemistry.

Design and Synthesis of Indole and Tetrahydroisoquinoline Hydantoin Derivatives as Human Chymase Inhibitors

G. Ferry, J. Boutin, P. Renard, 2004, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and biological evaluation of aristolactams.

P. Renard, B. Pfeiffer, A. Couture, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.

P. Renard, B. Pfeiffer, C. Monneret, 2006, European journal of medicinal chemistry.

Synthesis and antiproliferative activity of basic ethers of 1,2-dihydropyrrolo[1,2-a]indole, 6H-isoindolo[2,1-a]indole, and 6H-benz[5,6]isoindolo[2,1-a]indole.

P. Renard, B. Pfeiffer, C. Monneret, 2003, Oncology research.

Platelet Antiaggregant Methoxyphenylthienyl Ketoxime Ethers: Synthesis and Structure‐Activity Relationships

P. Renard, J. Vercauteren, M. Varache-Lembège, 1995, Archiv der Pharmazie.

Synthesis and inhibitory effects on platelet aggregation of 3-(2-thienyl)- and 3-(1-imidazolyl)-1,2-benzisoxazole derivatives

P. Renard, M. Varache-Lembège, A. Nuhrich, 1994 .

N-substituted oxazolo[5,4-b]pyridin-2(1H)-ones: a new class of non-opiate antinociceptive agents.

P. Renard, D. Caignard, B. Pfeiffer, 1995, Journal of medicinal chemistry.

Immunologically driven chemical engineering of antibodies for catalytic activity.

P. Renard, J. Grassi, C. Mioskowski, 2002, Journal of immunological methods.

3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans].

P. Renard, M. Rettori, D. Caignard, 1996, Journal of medicinal chemistry.

Synthesis of new pyrrolo(1,2-a)quinoxalines: potential non-peptide glucagon receptor antagonists

P. Renard, B. Pfeiffer, S. Rault, 1998 .

Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.

P Delagrange, M. Hamon, P. Renard, 1997, Journal of medicinal chemistry.

Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones.

P. Renard, A. Skaltsounis, E. Mikros, 2001, Bioorganic & medicinal chemistry.

Optimized access to alkyl thiocyanates

P. Renard, E. Leclerc, C. Mioskowski, 2001 .

Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.

P. Renard, B. Pfeiffer, C. Monneret, 2004, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of new benzodioxinic lactones as potential anticancer drugs.

C. Bailly, P. Renard, D. Caignard, 2007, Journal of medicinal chemistry.

Synthesis of Isoquinolines and Tetrahydroisoquinolines as Potential Antitumor Agents.

P. Renard, D. Caignard, M. D. Pujol, 2002 .

Synthesis and cytotoxic activity of tetracenomycin D and of saintopin analogues.

P. Renard, B. Pfeiffer, B. Renoux, 2002, Bioorganic & medicinal chemistry.

Synthesis and Cytotoxic Evaluation of Novel Thiazolocarbazoles. Part II1

P. Renard, B. Pfeiffer, G. Guillaumet, 2003, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and Cytotoxic Evaluation of Novel Thiazolocarbazoles

P. Renard, B. Pfeiffer, G. Guillaumet, 2002, Journal of enzyme inhibition and medicinal chemistry.

5‐Alkoxyoxazole – A Versatile Building Block in (Bio)organic Synthesis

P. Renard, C. Sabot, Kévin Renault, 2016 .

Substituted pyrido[3,2-b]oxazin-3(4H)-ones: synthesis and evaluation of antinociceptive activity.

P. Renard, B. Pfeiffer, G. Guillaumet, 1998, Bioorganic & medicinal chemistry.

Synthesis and Cytotoxic Activity of Thiazolofluorenone Derivatives

P. Renard, B. Pfeiffer, G. Guillaumet, 2004, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and cytotoxic and antitumor activity of benzo[b]pyrano[3, 2-h]acridin-7-one analogues of acronycine.

P. Renard, B. Pfeiffer, F. Tillequin, 2000, Journal of medicinal chemistry.

Palladium‐Catalyzed Preparation of N‐Alkylated Tacrine and Huprine Compounds

P. Renard, L. Jean, C. Ronco, 2011 .

Lewis acid catalyzed room-temperature Michaelis-Arbuzov rearrangement.

P. Renard, E. Leclerc, A. Valleix, 2003, Angewandte Chemie.

3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.

P. Renard, D. Caignard, B. Pfeiffer, 1994, Journal of medicinal chemistry.

Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones.

P. Renard, M. Msaddek, C. Sabot, 2017, Organic & biomolecular chemistry.

Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.

P. Renard, B. Pfeiffer, S. Gallet, 2009, Bioorganic & medicinal chemistry.

Antitumor agents. Synthesis and biological evaluation of new compounds related to podophyllotoxin, containing the 2,3-dihydro-1,4-benzodioxin system.

P. Renard, D. Caignard, M. D. Pujol, 2001, European journal of medicinal chemistry.

Chapter 4 – Phosphoryl Compounds

P. Renard, C. Timperley, Catherine Gomez, 2015 .

Straightforward access to protected syn alpha-amino-beta-hydroxy acid derivatives.

P. Renard, X. Franck, G. Clavé, 2008, Angewandte Chemie.

Straightforward Access to Protectedsyn a-Amino--hydroxy Acid Derivatives

P. Renard, X. Franck, G. Clavé, 2008 .

2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds.

P. Renard, A. Skaltsounis, P. Magiatis, 2001, Bioorganic & medicinal chemistry.

Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity.

P. Renard, J. Grassi, C. Mioskowski, 2002, Journal of the American Chemical Society.

Synthesis and biological evaluation of modified acridines: the effect of N- and O- substituent in the nitrogenated ring on antitumor activity.

P. Renard, D. Caignard, M. D. Pujol, 2006, European journal of medicinal chemistry.

Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline receptor selective ligand with hypotensive activity.

P. Renard, B. Pfeiffer, S. Schann, 2001, Journal of medicinal chemistry.

Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 1. Synthesis and biological activities of N-benzyl-N'-(arylalkyl)-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines .

G. Dive, P. Renard, B. Pfeiffer, 1997, Journal of medicinal chemistry.

3D-QSAR CoMFA study on imidazolinergic I(2) ligands: a significant model through a combined exploration of structural diversity and methodology.

L Morin-Allory, P. Renard, C. Marot, 2000, Journal of medicinal chemistry.

Agomelatine, the first melatonergic antidepressant: discovery, characterization and development

M. Millan, P. Renard, C. Muńoz, 2010, Nature Reviews Drug Discovery.

1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials.

P. Renard, C. Andraud, Y. Bretonnière, 2016, The Journal of organic chemistry.

1,3-dienylboronates in diels-alder reaction: Part III

P. Renard, J. Lallemand, Y. Six, 1997 .

1,3-Dienylboronates in Diels-Alder reactions: Part II1

P. Renard, J. Lallemand, 1996 .

Design and synthesis of new naphthalenic derivatives as ligands for 2-[125I]iodomelatonin binding sites.

P Delagrange, P. Renard, P. Delagrange, 1995, Journal of medicinal chemistry.

An Efficient Method for the Preparation of Antitumoral α‐Keto‐imines Benzyldihydroisoquinolines by Selective Benzylic Oxidation with C/Pd in Acetonitrile.

P. Renard, D. Caignard, A. Bermejo, 2002 .

Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3).

J. Boutin, D. Lesieur, P. Renard, 2002, Journal of medicinal chemistry.

Towards the total synthesis of clerodin. Part I.

P. Renard, J. Lallemand, H. Bouchard, 1991 .

Straightforward access to water-soluble unsymmetrical sulfoxanthene dyes: application to the preparation of far-red fluorescent dyes with large stokes' shifts.

A. Romieu, P. Renard, A. Chevalier, 2014, Chemistry.

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.

M. Bartolini, J. Sussman, M. Naldi, 2019, European journal of medicinal chemistry.

Synthetic Route to Rare Isoindolones Derivatives.

P. Renard, L. Jean, S. Routier, 2015 .

Thermally controlled decarboxylative [4 + 2] cycloaddition between alkoxyoxazoles and acrylic acid: expedient access to 3-hydroxypyridines.

P. Renard, Vincent Tognetti, L. Joubert, 2013, Organic letters.

News naphtylethylurees naphtylethylthiourees and their process for the preparation and pharmaceutical compositions containing them.

P. Depreux, D. Lesieur, P. Renard, 1991 .

Antibody-Catalyzed Decarboxylative Oxidation of Vanillylmandelic Acid

P. Renard, J. Grassi, C. Mioskowski, 1998 .

Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists.

J. Boutin, D. Lesieur, P. Renard, 2006, Bioorganic & medicinal chemistry.

Metal-free decarboxylative hetero-Diels–Alder synthesis of 3-hydroxypyridines: a rapid access to N-fused bicyclic hydroxypiperidine scaffolds.

P. Renard, Vincent Tognetti, L. Joubert, 2014, The Journal of organic chemistry.

Optimized strategies to synthesize β-cyclodextrin-oxime conjugates as a new generation of organophosphate scavengers.

P. Renard, S. Müller, F. Worek, 2011, Organic & biomolecular chemistry.

Cytotoxic Bis-3,4-dihydro-β-carbolines and Bis-β-carbolines

P. Renard, B. Pfeiffer, J. Sapi, 2002 .

Synthesis and cytotoxic and antitumor activity of 1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine diacid hemiesters and carbamates.

P. Renard, B. Pfeiffer, F. Tillequin, 2004, Chemical & pharmaceutical bulletin.

Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Journal of medicinal chemistry.

New carboxylic acid derivatives of 7-oxo-2,3,7,14- tetrahydro-1H-benzo [b] pyrano [3,2 h] acridine, their process for the preparation and pharmaceutical compositions containing them

P. Renard, B. Pfeiffer, F. Tillequin, 1999 .

Stereoselective access to polyfunctionalized decalins

P. Renard, J. Lallemand, Céline Poirel, 1994 .

Expeditious microwave-assisted synthesis of 5-alkoxyoxazoles from α-triflyloxy esters and nitriles.

P. Renard, C. Sabot, Laurie-Anne Jouanno, 2012, The Journal of organic chemistry.

Design, synthesis and antiproliferative activity of tripentones: a new series of antitubulin agents.

P. Renard, S. Rault, V. Lisowski, 2001, Bioorganic & medicinal chemistry letters.

Trimethylsilyl halide-promoted Michaelis-Arbuzov rearrangement.

P. Renard, C. Mioskowski, P. Vayron, 2003, Organic letters.

McMurry intermolecular cross-coupling between an ester and a ketone: scope and limitations

P. Renard, E. Leclerc, C. Mioskowski, 2002 .

Efficient selective synthesis of 2-substituted indoles from complex-base-promoted arynic cyclisations

P. Renard, B. Pfeiffer, P. Caubére, 1997 .

Azo-Based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges.

A. Romieu, P. Renard, A. Chevalier, 2017, Chemistry, an Asian journal.

New cytotoxic analogues of annonaceous acetogenins.

P. Renard, R. Grée, B. Renoux, 2001, Anti-Cancer Drug Design.

Synthesis and cytotoxic activity of acetogenin analogues.

P. Renard, R. Grée, B. Renoux, 2000, Bioorganic & Medicinal Chemistry Letters.

Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.

C. Bailly, P. Colson, P. Renard, 2004, Journal of medicinal chemistry.

Synthesis and luminescence properties of new red-shifted absorption lanthanide(III) chelates suitable for peptide and protein labelling.

A. Romieu, P. Renard, L. Jean, 2011, Organic & biomolecular chemistry.

New insights into the water-solubilization of thiol-sensitive fluorogenic probes based on long-wavelength 7-hydroxycoumarin scaffolds

A. Romieu, P. Renard, Benôit Roubinet, 2014 .

Chemiluminescent probe for the in vitro detection of protease activity.

A. Romieu, P. Renard, L. Jean, 2007, Organic letters.

High-throughput screening of enantioselective catalysts by immunoassay.

Alain Wagner, Frédéric Taran, P. Renard, 2002, Angewandte Chemie.

Water-solubilisation and bio-conjugation of a red-emitting BODIPY marker.

A. Romieu, P. Renard, G. Ulrich, 2011, Organic & biomolecular chemistry.

Improved synthetic pathway for the derivatization of huprine scaffold

P. Renard, L. Jean, C. Ronco, 2010 .

Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle.

P. Renard, D. Caignard, P Renard, 2001, Bioorganic & medicinal chemistry letters.

Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure

P. Renard, O. Lockridge, F. Nachon, 2012, The FEBS journal.

Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies.

P. Renard, J. Fredy, C. Sabot, 2018, Bioconjugate chemistry.

Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group.

P. Renard, D. Caignard, P Renard, 2001, European journal of medicinal chemistry.

One‐Pot Synthesis of Diazirines and 15 N 2 ‐Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight

P. Renard, X. Franck, T. Tite, 2021, Advanced Synthesis & Catalysis.

STRUCTURE-ACTIVITY REUATIONSHIPS OF MEUATONIN ANALOGUES

P. Depreux, D. Lesieur, P. Renard, 1995, European Journal of Medicinal Chemistry.

Development of Melatonin Analogs

P. Renard, P. Delagrange, D. Caignard, 1995 .

Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.

P. Depreux, D. Lesieur, P. Renard, 1998, Journal of medicinal chemistry.

Dearomatization of a 3-Hydroxypyridine Through an Unexpected Oxidative Deformylation Process: An Entry to Azacyclohexadienones

P. Renard, C. Sabot, A. Kriaa, 2020, Synlett.

Synthesis of New Aromatic Pyrrolo[2,1- c] [1,4]benzodiazepines and Pyrrolo[1,2- a] thieno[3,2- e] [1,4]diazepines as Anti-tumoral Agents

P. Renard, S. Rault, V. Lisowski, 2002, Journal of enzyme inhibition and medicinal chemistry.

Novel naphthalenic ligands with high affinity for the melatonin receptor.

D. Lesieur, P. Renard, B. Pfeiffer, 1992, Journal of medicinal chemistry.

Screening of Ligand Binding on Melatonin Receptor Using Non-Peptide Combinatorial Libraries

J. Fauchère, J. Nicolas, J. Boutin, 2000, Journal of receptor and signal transduction research.

Melatonin analogues as agonists and antagonists in the circadian system and other brain areas.

P. Renard, P. Delagrange, E. Mocaer, 1996, European journal of pharmacology.

Regioselective synthesis of o-triazolyl-1,5-benzodiazepin-2-ones and o-isoxazolyl-1,5-benzodiazepin-2-ones via copper-catalyzed 1,3-dipolar cycloaddition reactions

P. Renard, M. Msaddek, C. Sabot, 2017 .

Synthesis and structure-activity relationships of novel arylalkyl 4-benzyl piperazine derivatives as sigma site selective ligands.

P. Renard, M. Rettori, B. Pfeiffer, 2000, European journal of medicinal chemistry.

Synthesis and analgesic evaluation of some 1,1-disubstituted 3-carboxy-4-phenyl-1,2,3,4-tetrahydro-β-carboline derivatives

P. Renard, B. Pfeiffer, L. Jeannin, 1995 .

Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via palladium-catalyzed intramolecular arylation

P. Renard, B. Pfeiffer, P. Pinson, 2004 .

New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization.

P. Renard, B. Pfeiffer, S. Rault, 2003, Journal of medicinal chemistry.

Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands.

J. Nicolas, J. Boutin, D. Lesieur, 2002, Journal of medicinal chemistry.

S 26948

P. Renard, B. Lefebvre, L. Pénicaud, 2007, Diabetes.

Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.

P. Renard, B. Pfeiffer, C. Monneret, 2005, Journal of medicinal chemistry.

Metalloenzyme-mediated thiol-yne addition towards photoisomerizable fluorescent dyes.

P. Renard, Vincent Tognetti, L. Joubert, 2022, Chemistry.

Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer

A. Romieu, L. Thiberville, P. Renard, 2019, BMC Pulmonary Medicine.

Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3.

J. Boutin, P. Renard, P. Delagrange, 2011, European journal of medicinal chemistry.

A FRET-based probe for fluorescence sensing of sulfide/sulfite analytes, using a novel long-wavelength water-soluble 7-hydroxycoumarin as reporter fluorophore

A. Romieu, P. Renard, Benôit Roubinet, 2015 .

8-Amino-5-nitro-6-phenoxyquinolines: Potential Non-peptidic Neuropeptide Y Receptor Ligands

J. Boutin, P. Renard, P. Pinson, 2002, Journal of Enzyme Inhibition and Medicinal Chemistry.

Effects of both a melatonin agonist and antagonist on seasonal changes in body mass and energy intake in the garden dormouse.

D. Lesieur, P. Renard, P. Delagrange, 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Food intake regulation in rodents: Y5 or Y1 NPY receptors or both?

J. Fauchère, P. Renard, J. Boutin, 2000, Canadian journal of physiology and pharmacology.

6-aminoalkyloxazolo[4,5-b]pyridin-2(3H)-ones: synthesis and evaluation of antinoceptive activity.

P. Renard, B. Pfeiffer, G. Guillaumet, 1998, Bioorganic & medicinal chemistry.

Combination delivery of two oxime‐loaded lipid nanoparticles: Time‐dependent additive action for prolonged rat brain protection

P. Renard, P. Masson, L. Zakharova, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Nycthemeral variations of cholecystokinin action on intestinal motility in rats: effects of melatonin and S 20928, a melatonin receptor antagonist

P. Renard, P. Delagrange, S. Pellissier, 2000, Neuropeptides.

Straightforward synthesis of bioconjugatable azo dyes. Part 2: Black Hole Quencher-2 (BHQ-2) and BlackBerry Quencher 650 (BBQ-650) scaffolds

A. Romieu, P. Renard, A. Chevalier, 2014 .

In Vitro and Ex Vivo Evaluation of Smart Infra-Red Fluorescent Caspase-3 Probes for Molecular Imaging of Cardiovascular Apoptosis

A. Romieu, F. Lallemand, V. Richard, 2011, International journal of molecular imaging.

Strategies for the selection of catalytic antibodies against organophosphorus nerve agents.

P. Renard, P. Masson, I. Smirnov, 2013, Chemico-biological interactions.

Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).

J. Boutin, M. Spedding, P. Renard, 2012, European journal of medicinal chemistry.

Design and synthesis of 3-phenyltetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands. Part II.

J. Boutin, D. Lesieur, P. Renard, 2009, Bioorganic & Medicinal Chemistry.

Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands.

J. Boutin, D. Lesieur, P. Renard, 2008, Bioorganic & medicinal chemistry.

Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors.

L Morin-Allory, D. Lesieur, P. Renard, 1998, Journal of medicinal chemistry.

First tricyclic oximino derivatives as 5-HT3 ligands.

P Delagrange, P. Renard, B. Pfeiffer, 2001, Bioorganic & medicinal chemistry letters.

Water solubilization of xanthene dyes by post-synthetic sulfonation in organic media

A. Romieu, P. Renard, M. Lemaire, 2010 .

Synthesis and biological activity of conformationally restricted tricyclic analogs of the hormone melatonin

P. Depreux, D. Lesieur, P. Renard, 1996 .

Substituted 3-amino and/or 3-aminomethyl-3,4-dihydro-2H-1-benzopyrans: synthesis and biological activity.

P. Renard, M. Rettori, B. Pfeiffer, 2000, Bioorganic & medicinal chemistry.

N,N-disubstituted aminomethyl benzofuran derivatives: synthesis and preliminary binding evaluation.

P. Renard, M. Rettori, B. Pfeiffer, 1999, Bioorganic & medicinal chemistry.

Reinvestigation of the synthesis of “covalent-assembly” type probes for fluoride ion detection. Identification of novel 7-(diethylamino)coumarins with aggregation-induced emission properties

A. Romieu, P. Renard, Valentin Quesneau, 2019, Tetrahedron Letters.

Water-soluble red-emitting distyryl-borondipyrromethene (BODIPY) dyes for biolabeling.

A. Romieu, P. Renard, G. Ulrich, 2012, Chemistry.

Synthesis and reactivity of a bis-sultone cross-linker for peptide conjugation and [18F]-radiolabelling via unusual "double click" approach.

A. Romieu, P. Renard, Cédric Bouteiller, 2012, Organic & biomolecular chemistry.

N-Fmoc-α-sulfo-β-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy.

A. Romieu, P. Renard, T. Bruckdorfer, 2011, Organic & biomolecular chemistry.

7-hydroxycoumarin-hemicyanine hybrids: a new class of far-red emitting fluorogenic dyes.

A. Romieu, P. Renard, M. Massonneau, 2008, Organic letters.

Postsynthetic Derivatization of Fluorophores with α-Sulfo-β-alanine Dipeptide Linker. Application to the Preparation of Water-Soluble Cyanine and Rhodamine Dyes

Dominique Brossard, A. Romieu, P. Renard, 2008 .

Agomelatine, the first melatonergic antidepressant: discovery, characterization and development

M. Millan, P. Renard, C. Muńoz, 2010, Nature Reviews Drug Discovery.

On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach

P. Renard, E. Derat, F. Nachon, 2017, Chembiochem : a European journal of chemical biology.

Huprine Derivatives as Sub‐Nanomolar Human Acetylcholinesterase Inhibitors: From Rational Design to Validation by X‐ray Crystallography

P. Renard, J. Colletier, M. Weik, 2012, ChemMedChem.

A novel heterotrifunctional peptide-based cross-linking reagent for facile access to bioconjugates. Applications to peptide fluorescent labelling and immobilisation.

A. Romieu, P. Renard, H. Volland, 2008, Organic & biomolecular chemistry.

New insights into the kinetic target-guided synthesis of protein ligands.

P. Renard, E. Oueis, C. Sabot, 2015, Chemical communications.

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase.

P. Renard, A. Wagner, F. Nachon, 2011, Chemical communications.

Respective contributions of α‐adrenergic and non‐adrenergic mechanisms in the hypotensive effect of imidazoline‐like drugs

J. Boutin, P. Renard, B. Pfeiffer, 2001, British journal of pharmacology.

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice.

V. Andrisano, M. Bartolini, I. Silman, 2020, Journal of medicinal chemistry.

Flow neutralisation of sulfur-containing chemical warfare agents with Oxone: packed bed vs. aqueous solution

P. Renard, L. Jean, J. Legros, 2021, Green Chemistry.

Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning.

P. Renard, M. Katalinić, Z. Kovarik, 2020, ACS chemical neuroscience.

Synthesis and cytotoxic activity of benzophenanthrolinone analogues of acronycine.

P. Renard, B. Pfeiffer, J. Bongui, 2001, Chemical and pharmaceutical bulletin.

A highly sensitive competitive enzyme immunoassay of broad specificity quantifying microcystins and nodularins in water samples.

François Fenaille, Hervé Volland, P. Renard, 2009, Toxicon : official journal of the International Society on Toxinology.

Structure–activity relationships and structural conformation of a novel urotensin II-related peptide

Hassan Oulyadi, Pierre Renard, Jérôme Leprince, 2004, Peptides.

Structure–Activity Relationships of Human Urotensin II and Related Analogues on Rat Aortic Ring Contraction

Pierre Renard, Jérôme Leprince, Hubert Vaudry, 2003, Journal of enzyme inhibition and medicinal chemistry.

Anxiolytic properties of (+) s 20499, a novel serotonin 5‐HT1A full agonist, in the elevated plus‐maze and social interaction tests

P. Renard, E. Mocaer, B. Guardiola, 1994 .

3-Benzo[b]furyl- and 3-benzo[b]thienylaminobutyric acids as GABAB ligands. Synthesis and structure-activity relationship studies

P. Renard, M. Rettori, D. Caignard, 1996 .

Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents.

P. Renard, B. Pfeiffer, S. Léonce, 2000, Bioorganic & medicinal chemistry letters.

Functionalisation of the alkoxy group of alkyl aryl ethers. Demethylation, alkylthiolation and reduction of 5-methoxyindoles

P. Renard, M. Nardelli, S. Ianelli, 1994 .

Design of new anticancer drugs. II. Easy arynic access to benzocyclobutacarbazoles, a new family of antitumor agents

P. Renard, B. Pfeiffer, P. Caubére, 1998 .

Functionalization of the Alkoxy Group of Alkyl Aryl Ethers. Demethylation, Alkylthiolation and Reduction of 5‐Methoxyindoles.

P. Renard, M. Nardelli, S. Ianelli, 1995 .

Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes.

P. Renard, B. Pfeiffer, A. Lamouri, 1996, The Journal of pharmacology and experimental therapeutics.

A novel series of 2,6,7-substituted 2,3-dihydro-1,4-benzodioxin and 2,6,7-substituted 1,4-benzodioxin derivatives as lipid peroxidation inhibitors. Structure-activity relationships for high inhibition of human low-density lipoprotein peroxidation.

P. Renard, B. Pfeiffer, G. Guillaumet, 2001, Journal of Medicinal Chemistry.

Evidence for Synergy Between &agr;2-Adrenergic and Nonadrenergic Mechanisms in Central Blood Pressure Regulation

P. Renard, L. Monassier, S. Schann, 2002, Circulation.

Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis

A. Romieu, H. Vaudry, P. Renard, 2014, Journal of Molecular Neuroscience.

Synthesis and Structure−Activity Relationships of New 1,3-Disubstituted Cyclohexanes as Structurally Rigid Leukotriene B4 Receptor Antagonists

P. Renard, B. Pfeiffer, J. Girard, 1999 .

Expeditious Synthesis and Cytotoxic Activity of New Cyanoindolo[3,2‐c]quinolines and Benzimidazo[1,2‐c]quinazolines.

P. Renard, B. Pfeiffer, G. Guillaumet, 2000 .

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

P. Renard, F. Nachon, Guillaume Mercey, 2016 .

Bifunctional mannoside-glucosinolate glycoconjugates as enzymatically triggered isothiocyanates and FimH ligands.

P. Renard, R. Nehmé, P. Morin, 2018, Organic & biomolecular chemistry.

Straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals

P. Renard, Guillaume Mercey, T. Verdelet, 2011 .

Effects of S-21007, a potent 5-HT3 partial agonist, in mouse anxiety.

P. Renard, B. Pfeiffer, S. Rault, 1999, Zhongguo yao li xue bao = Acta pharmacologica Sinica.

Maleimide-based metal-free ligation with dienes: a comparative study.

P. Renard, C. Sabot, Kévin Renault, 2020, Organic & biomolecular chemistry.

A convenient 3-step synthesis of 3-acetamido-6-arylpyridazines directed to novel Y5 receptor antagonist.

C. Wermuth, J. Boutin, P. Renard, 2002, Chemical & pharmaceutical bulletin.

Synthesis of polysubstituted 3-hydroxypyridines via the revisited hetero-Diels-Alder reaction of 5-alkoxyoxazoles with dienophiles.

P. Renard, E. Oueis, C. Sabot, 2012, Chemical communications.

Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production.

C. Sarrauste de Menthière, P. Renard, B. Pfeiffer, 2004, European journal of medicinal chemistry.

Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase.

P. Renard, F. Nachon, Guillaume Mercey, 2012, Journal of medicinal chemistry.

Interaction of S 21007 with 5-HT3 receptors. In vitro and in vivo characterization.

M. Hamon, P. Renard, B. Pfeiffer, 1996, European journal of pharmacology.

Trifunctional peptide pseudo reagent, uses thereof and applications.

A. Romieu, P. Renard, H. Volland, 2007 .

Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor.

M. Bartolini, M. Naldi, P. Renard, 2020, Biochemical pharmacology.

A miniaturized peptidyl-prolyl isomerase enzyme assay.

U. Holzgrabe, P. Renard, N. Harmer, 2017, Analytical biochemistry.

Azo-sulforhodamine dyes: a novel class of broad spectrum dark quenchers.

A. Romieu, P. Renard, A. Chevalier, 2014, Organic letters.

Reagent including four orthogonal functions and its uses

A. Romieu, P. Renard, S. Dautrey, 2014 .

Novel water-soluble near-infrared cyanine dyes: synthesis, spectral properties, and use in the preparation of internally quenched fluorescent probes.

A. Romieu, P. Renard, M. Massonneau, 2007, Bioconjugate chemistry.

Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle

P. Renard, B. Pfeiffer, B. Hugon, 2003 .

Regioselective Synthesis of Benzimidazolic Bioisosteres of Melatonin

P. Depreux, D. Lesieur, P. Renard, 1994 .

3-[5-(4,5-dihydro-1H-imidazol-2-yl)-furan-2-yl]phenylamine (Amifuraline), a promising reversible and selective peripheral MAO-A inhibitor.

P. Renard, S. Marchal-Victorion, P. Delagrange, 2006, Journal of medicinal chemistry.

Antagonistic Effects of S 22153, a New mt1 and MT2 Receptor Ligand, on the Neophobia-Reducing Properties of Melatonin in BALB/c Mice

D. Lesieur, P. Renard, M. Rettori, 1999, Pharmacology Biochemistry and Behavior.

Soft and effective detoxification of a VX simulant in a nylon 3D printed basic flow reactor

P. Renard, C. Vallières, L. Sigot, 2021, Green Chemistry.

Selective Demethylation and Demethoxy Thioalkylation of 5-Methoxyindoles

P. Renard, B. Jamart-Grégoire, P. Caubére, 1994 .

Selective Demethylation and Demethoxythioalkylation of 5‐ Methoxyindoles.

P. Renard, B. Jamart-Grégoire, P. Caubére, 1994 .

An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice.

P. Renard, A. Calas, F. Nachon, 2017, Chemico-biological interactions.

A selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging.

P. Renard, E. Krejci, V. Bernard, 2016, Chemical communications.

Dimers from dechlorinated rebeccamycin: synthesis, interaction with DNA, and antiproliferative activities.

C. Bailly, P. Renard, B. Pfeiffer, 2002, European journal of medicinal chemistry.

Syntheses and antiproliferative activities of new rebeccamycin derivatives with the sugar unit linked to both indole nitrogens.

P. Renard, B. Pfeiffer, M. Prudhomme, 2002, Journal of medicinal chemistry.

The use of enzyme immunoassays for the detection of abzymatic activities. Application to an enantioselective thioacetal hydrolysis activity.

P. Renard, J. Grassi, C. Mioskowski, 2002, Journal of immunological methods.

Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis

A. Romieu, H. Vaudry, P. Renard, 2014, Journal of Molecular Neuroscience.

5‐Substituted 3,4‐dihydro‐3‐amino‐2H‐1‐benzopyran derivatives: synthesis and interaction with serotoninergic receptors

P. Renard, B. Pfeiffer, P. Delagrange, 2001, The Journal of pharmacy and pharmacology.

N-substituted aminohydroxypyridines as potential non-opioid analgesic agents.

P. Renard, B. Pfeiffer, G. Guillaumet, 1995, Bioorganic & medicinal chemistry.

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.

M. Bartolini, J. Sussman, M. Naldi, 2019, European journal of medicinal chemistry.

A novel sulfonated prosthetic group for [18F]-radiolabelling and imparting water solubility of biomolecules and cyanine fluorophores.

A. Romieu, P. Renard, J. Hardouin, 2013, Organic & biomolecular chemistry.

Photophysical properties of quinoxalin-2(1H)-ones: application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide

P. Renard, C. Sabot, Kévin Renault, 2017 .

[Melatonin, a pertinent prototype for therapeutic innovation].

D. Lesieur, P. Renard, C. Marot, 1998, Therapie.

Receptor- and Ligand-Based Study on Novel 2, 2′-Bithienyl Derivatives as Non-Peptidic AANAT Inhibitors

Xiao Feng, Jana Sopkova-de Oliveira Santos, Ronan Bureau, 2010, J. Chem. Inf. Model..

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents.

P. Renard, E. Pǎunescu, F. Nachon, 2013, Chemico-biological interactions.

Improved Access to Huprine Derivatives Functionalized at Position 9

P. Renard, L. Jean, Monika Cieslikiewicz-Bouet, 2016 .

Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure

P. Renard, O. Lockridge, F. Nachon, 2012, The FEBS journal.

A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis.

A. Romieu, P. Renard, Catherine Nury, 2015, Analytical chemistry.