D. Caignard

发表

Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.

T. Taverne, O. Diouf, P. Depreux, 1998, Journal of medicinal chemistry.

Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines.

P Delagrange, M. Hamon, B. Guardiola-Lemaitre, 1996, Journal of medicinal chemistry.

Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands.

D. Caignard, P. Delagrange, S. El Kazzouli, 2011, European journal of medicinal chemistry.

Preparative enantiomeric separation of potent AMP-activated protein kinase activator by HPLC on amylose-based chiral stationary phase. Determination of enantiomeric purity and assignment of absolute configuration.

D. Caignard, C. Vaccher, J. Bonte, 2008, Journal of pharmaceutical and biomedical analysis.

Synthesis and Structure-Affinity Relationships of Selective High- Affinity 5-HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers

Y. Charnay, D. Caignard, S. Rault, 2012 .

3,4‐Dihydro‐3‐amino‐2H‐1‐benzopyran Derivatives as 5‐HT1A Receptor Ligands and Potential Anxiolytic Agents. Part 1. Synthesis and Structure‐Activity Relationship Studies.

P. Renard, D. Caignard, B. Pfeiffer, 1994 .

Molecular characterization of the AMPA-receptor potentiator S70340 in rat primary cortical culture: Whole-genome expression profiling

L. Danober, D. Caignard, P. Lestage, 2011, Neuroscience Research.

Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3.

J. Boutin, D. Lesieur, P. Renard, 2008, Bioorganic & medicinal chemistry.

Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.

Y. Charnay, D. Caignard, S. Rault, 2012, Journal of medicinal chemistry.

Syntheses and antitumor targeting G1 phase of the cell cycle of benzoyldihydroisoquinolines and related 1-substituted isoquinolines.

P. Renard, D. Caignard, R. Enriz, 2002, Journal of medicinal chemistry.

Synthesis of tetracyclic dioxygenated isoquinolines and their cytotoxic activity

P. Renard, D. Caignard, M. D. Pujol, 2008 .

Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents.

P. Peixoto, C. Bailly, D. Caignard, 2005, Journal of medicinal chemistry.

N-substituted oxazolo[5,4-b]pyridin-2(1H)-ones: a new class of non-opiate antinociceptive agents.

P. Renard, D. Caignard, B. Pfeiffer, 1995, Journal of medicinal chemistry.

3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans].

P. Renard, M. Rettori, D. Caignard, 1996, Journal of medicinal chemistry.

Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.

P Delagrange, M. Hamon, P. Renard, 1997, Journal of medicinal chemistry.

Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties.

D. Caignard, J. Rubio-Martínez, M. D. Pujol, 2018, European journal of medicinal chemistry.

Synthesis and structure-activity relationships of new benzodioxinic lactones as potential anticancer drugs.

C. Bailly, P. Renard, D. Caignard, 2007, Journal of medicinal chemistry.

Synthesis of Isoquinolines and Tetrahydroisoquinolines as Potential Antitumor Agents.

P. Renard, D. Caignard, M. D. Pujol, 2002 .

5-HT1A and 5-HT2A ligands with anxiolytic and antipanic-like properties

O. Diouf, P. Depreux, D. Lesieur, 1997 .

3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.

P. Renard, D. Caignard, B. Pfeiffer, 1994, Journal of medicinal chemistry.

Antitumor agents. Synthesis and biological evaluation of new compounds related to podophyllotoxin, containing the 2,3-dihydro-1,4-benzodioxin system.

P. Renard, D. Caignard, M. D. Pujol, 2001, European journal of medicinal chemistry.

Synthesis and biological evaluation of modified acridines: the effect of N- and O- substituent in the nitrogenated ring on antitumor activity.

P. Renard, D. Caignard, M. D. Pujol, 2006, European journal of medicinal chemistry.

An Efficient Method for the Preparation of Antitumoral α‐Keto‐imines Benzyldihydroisoquinolines by Selective Benzylic Oxidation with C/Pd in Acetonitrile.

P. Renard, D. Caignard, A. Bermejo, 2002 .

Synthesis and biological evaluation of novel benzodioxinocarbazoles (BDCZs) as potential anticancer agents.

D. Caignard, S. Routier, A. Pierré, 2010, Bioorganic & medicinal chemistry letters.

Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle.

P. Renard, D. Caignard, P Renard, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group.

P. Renard, D. Caignard, P Renard, 2001, European journal of medicinal chemistry.

5‐HT1A and 5‐HT2A Ligands with Anxiolytic and Antipanic‐Like Properties.

O. Diouf, P. Depreux, D. Lesieur, 1998 .

New Quinoxaline Derivatives as Potential MT1 and MT2 Receptor Ligands

D. Caignard, P. Delagrange, A. Monge, 2012, Molecules.

3-Benzo[b]furyl- and 3-benzo[b]thienylaminobutyric acids as GABAB ligands. Synthesis and structure-activity relationship studies

P. Renard, M. Rettori, D. Caignard, 1996 .

Synthesis and Evaluation of New 2-piperazinylbenzothiazoles With High 5-ht1a and 5-ht3 Affinities

O. Diouf, P. Depreux, J. Poupaert, 1995 .