B. Pfeiffer

发表

Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.

T. Taverne, O. Diouf, P. Depreux, 1998, Journal of medicinal chemistry.

Synthesis of granulatimide analogues bearing a maleimide instead of an imidazole heterocycle

P. Renard, B. Pfeiffer, B. Hugon, 2003 .

Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.

P. Depreux, D. Lesieur, B. Guardiola-Lemaitre, 1994, Bioorganic & medicinal chemistry.

Structure–activity relationships of urotensin II and URP

H. Vaudry, P. Renard, B. Pfeiffer, 2008, Peptides.

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

G. Ferry, J. Boutin, B. Pfeiffer, 2011, Life sciences.

Synthesis and structure-activity relationships of novel 2-amino alkyl chromones and related derivatives as a site-selective ligands

B. Guardiola-Lemaitre, P. Renard, M. Rettori, 1998 .

Cancer chemotherapy: a SN-38 (7-ethyl-10-hydroxycamptothecin) glucuronide prodrug for treatment by a PMT (Prodrug MonoTherapy) strategy.

P. Renard, B. Pfeiffer, C. Monneret, 2003, Bioorganic & medicinal chemistry letters.

Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines.

P Delagrange, M. Hamon, B. Guardiola-Lemaitre, 1996, Journal of medicinal chemistry.

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

B. Pfeiffer, S. Rault, F. Lezoualc’h, 2009, Bioorganic & medicinal chemistry.

Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.

B. Pfeiffer, J. Hickman, R. Golsteyn, 2008, Bioorganic & medicinal chemistry.

Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines

L. Meijer, C. Bailly, P. Renard, 2005 .

Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors.

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2007, European journal of pharmacology.

Synthesis of dipyrrolo [3,4-a:3,4-c]carbazole-1,3,4,6-tetraones bearing a sugar moiety.

B. Pfeiffer, M. Prudhomme, F. Anizon, 2006 .

Synthesis of bridged aza-rebeccamycin analogues

B. Pfeiffer, M. Prudhomme, S. Messaoudi, 2005 .

Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Bioorganic & medicinal chemistry.

Analogues of antifungal tjipanazoles from rebeccamycin.

C. Bailly, M. Sancelme, P. Renard, 2004, Bioorganic & medicinal chemistry.

Syntheses and antiproliferative activities of rebeccamycin analogues bearing two 7-azaindole moieties.

P. Renard, B. Pfeiffer, M. Prudhomme, 2003, Bioorganic & medicinal chemistry.

Potent antihyperglycaemic property of a new imidazoline derivative S‐22068 (PMS 847) in a rat model of NIDDM

B. Guardiola-Lemaitre, P. Renard, B. Pfeiffer, 1998, British journal of pharmacology.

Rebeccamycin Derivatives as Dual DNA-Damaging Agents and Potent Checkpoint Kinase 1 Inhibitors

L. Meijer, P. Peixoto, B. Pfeiffer, 2008, Molecular Pharmacology.

Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2004 .

Cytotoxic pentacyclic triterpenoids from Combretum sundaicum and Lantana camara as inhibitors of Bcl-xL/BakBH3 domain peptide interaction.

O. Nosjean, J. Boutin, B. Pfeiffer, 2009, Journal of natural products.

Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1,4-dialkyl-, 1,4-dibenzyl, and 1-benzyl-4-alkyl-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines and isosteric analogues of imidazoline.

G. Dive, P. Renard, B. Pfeiffer, 1999, Journal of medicinal chemistry.

A convenient synthesis of 5-arylamino-4H-pyran-4-ones using palladium-catalyzed amination

B. Pfeiffer, C. Logé, B. Lesur, 2009 .

Structure-activity relationships of a novel series of urotensin II analogues: identification of a urotensin II antagonist.

H. Vaudry, P. Renard, B. Pfeiffer, 2006, Journal of medicinal chemistry.

Synthesis, antitumor activity, and mechanism of action of benzo[b]chromeno[6,5-g][1,8]naphthyridin-7-one analogs of acronycine.

B. Pfeiffer, Wen Tian, L. Kraus-Berthier, 2014, Journal of medicinal chemistry.

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells.

B. Pfeiffer, J. Hickman, R. Golsteyn, 2010, Cancer letters.

Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.

B. Pfeiffer, J. Hickman, M. Koch, 2001, Molecular pharmacology.

S 23521 decreases food intake and body weight gain in diet-induced obese rats.

P. Renard, B. Pfeiffer, R. Gomis, 2004, Obesity research.

3,4‐Dihydro‐3‐amino‐2H‐1‐benzopyran Derivatives as 5‐HT1A Receptor Ligands and Potential Anxiolytic Agents. Part 1. Synthesis and Structure‐Activity Relationship Studies.

P. Renard, D. Caignard, B. Pfeiffer, 1994 .

Design and synthesis of tubulin ligands based on epothilones: a preliminary study

P. Renard, B. Pfeiffer, P. Bertrand, 2002 .

Novel thiopyrano[3,2-b] and cycloalkeno[1,2-b]indole derivatives with high inhibitory properties in LTB4 production

P. Renard, B. Pfeiffer, B. Jamart-Grégoire, 1999 .

Novel benzopyridothiadiazepines as potential active antitumor agents.

P. Renard, B. Pfeiffer, P. Chavatte, 2005, Journal of medicinal chemistry.

Natural Inhibitors of the RhoA-p115 Complex from the Bark of Meiogyne baillonii.

G. Ferry, J. Boutin, B. Pfeiffer, 2018, Journal of natural products.

Synthesis, biological evaluation and docking studies of 4-amino-tetrahydroquinazolino[3,2-e]purine derivatives.

B. Pfeiffer, A. Farce, S. Léonce, 2010, European journal of medicinal chemistry.

Effect of the new imidazoline derivative S-22068 (PMS 847) on insulin secretion in vitro and glucose turnover in vivo in rats.

N. Morgan, P. Renard, B. Pfeiffer, 1999, European journal of pharmacology.

Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.

C. Bailly, P. Colson, B. Pfeiffer, 2004, Bioorganic & medicinal chemistry.

Hetarynic synthesis and chemical transformation of dihydrodipyridopyrazines

P. Renard, B. Pfeiffer, G. Guillaumet, 2002 .

Influence of the Stereoisomeric Position of the Reactive Acetate Groups of the Benzo[b]Acronycine derivative S23906-1 on Its DNA Alkylation, Helix-Opening, Cytotoxic, and Antitumor Activities

C. Bailly, B. Pfeiffer, F. Tillequin, 2009, Molecular Pharmacology.

Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors.

B. Pfeiffer, S. E. Kazzouli, S. El Kazzouli, 2006, Bioorganic & medicinal chemistry.

Expeditious synthesis and cytotoxic activity of new cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines.

P. Renard, B. Pfeiffer, G. Guillaumet, 2000, Bioorganic & medicinal chemistry letters.

Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring.

P. Peixoto, B. Pfeiffer, M. Prudhomme, 2006, Bioorganic & medicinal chemistry.

Synthesis of pyridino[3′,2′:4,5]pyrrolo[3,2-g]pyrrolo[3,4-e]indolizin-1,3-dione and pyrrolo[3,2-c]pyrazole skeletons

B. Pfeiffer, M. Prudhomme, F. Anizon, 2006 .

Synthesis of isogranulatimides A and B analogues possessing a 7-azaindole unit instead of an indole moiety

P. Renard, B. Pfeiffer, B. Hugon, 2003 .

Syntheses and antiproliferative activities of 7-azarebeccamycin analogues bearing one 7-azaindole moiety.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Journal of medicinal chemistry.

Synthesis and biological evaluation of 7-azaindolocarbazoles

C. Bailly, P. Renard, B. Pfeiffer, 2002 .

Benzoselenazolinone derivatives designed to be glutathione peroxidase mimetics feature inhibition of cyclooxygenase/5-lipoxygenase pathways and anti-inflammatory activity.

D. Lesieur, B. Pfeiffer, L. Rochette, 1994, Journal of medicinal chemistry.

Synthesis and Cytotoxic Activity of Benzopyranoxanthone Analogues of Benzo[b]acronycine and Psorospermine

P. Renard, B. Pfeiffer, F. Tillequin, 2001 .

Cytotoxic activities of novel hexahydroindolizino[8,7-b]indole derivatives prepared by 1,3-dipolar cycloaddition reactions of 3,4-dihydro-beta-carboline ylides.

P. Renard, B. Pfeiffer, G. Werner, 2001, Bioorganic & medicinal chemistry.

Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles.

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2008, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.

P. Renard, M. Rettori, B. Pfeiffer, 2003, Journal of medicinal chemistry.

Synthesis and in vitro evaluation of new 8-amino-1,4-benzoxazine derivatives as neuroprotective antioxidants.

B. Pfeiffer, B Pfeiffer, B. Lockhart, 1999, Journal of medicinal chemistry.

First synthesis and pharmacological evaluation of benzoindolizidine and benzoquinolizidine analogues of α- and β-peltatin

Eric Deniau, Pierre Renard, Axel Couture, 2000 .

Synthesis and cytotoxicity of analogues of the antibiotic BE 10988 inhibitors of DNA topoisomerase II.

C. Bailly, P. Renard, B. Pfeiffer, 1999, Bioorganic & medicinal chemistry letters.

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone.

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2008, European journal of medicinal chemistry.

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of dipyrrolo[3,4-a:3,4-c]carbazole-triones

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2006 .

Design and Synthesis of Indole and Tetrahydroisoquinoline Hydantoin Derivatives as Human Chymase Inhibitors

G. Ferry, J. Boutin, P. Renard, 2004, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and biological evaluation of aristolactams.

P. Renard, B. Pfeiffer, A. Couture, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.

P. Renard, B. Pfeiffer, C. Monneret, 2006, European journal of medicinal chemistry.

Synthesis and antiproliferative activity of basic ethers of 1,2-dihydropyrrolo[1,2-a]indole, 6H-isoindolo[2,1-a]indole, and 6H-benz[5,6]isoindolo[2,1-a]indole.

P. Renard, B. Pfeiffer, C. Monneret, 2003, Oncology research.

N-substituted oxazolo[5,4-b]pyridin-2(1H)-ones: a new class of non-opiate antinociceptive agents.

P. Renard, D. Caignard, B. Pfeiffer, 1995, Journal of medicinal chemistry.

3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans].

P. Renard, M. Rettori, D. Caignard, 1996, Journal of medicinal chemistry.

Synthesis of new pyrrolo(1,2-a)quinoxalines: potential non-peptide glucagon receptor antagonists

P. Renard, B. Pfeiffer, S. Rault, 1998 .

Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.

P Delagrange, M. Hamon, P. Renard, 1997, Journal of medicinal chemistry.

Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions.

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2006, Bioorganic & medicinal chemistry.

Synthesis of granulatimide bis-imide analogues

B. Pfeiffer, B. Hugon, M. Prudhomme, 2005 .

Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.

P. Renard, B. Pfeiffer, C. Monneret, 2004, Journal of medicinal chemistry.

Synthesis and cytotoxic activity of tetracenomycin D and of saintopin analogues.

P. Renard, B. Pfeiffer, B. Renoux, 2002, Bioorganic & medicinal chemistry.

Synthesis and Cytotoxic Evaluation of Novel Thiazolocarbazoles. Part II1

P. Renard, B. Pfeiffer, G. Guillaumet, 2003, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and Cytotoxic Evaluation of Novel Thiazolocarbazoles

P. Renard, B. Pfeiffer, G. Guillaumet, 2002, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and in vitro antitumour evaluation of benzothiazole-2-carbonitrile derivatives

B. Pfeiffer, T. Besson, J. Guillard, 1999 .

Substituted pyrido[3,2-b]oxazin-3(4H)-ones: synthesis and evaluation of antinociceptive activity.

P. Renard, B. Pfeiffer, G. Guillaumet, 1998, Bioorganic & medicinal chemistry.

Synthesis and Cytotoxic Activity of Thiazolofluorenone Derivatives

P. Renard, B. Pfeiffer, G. Guillaumet, 2004, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and cytotoxic and antitumor activity of benzo[b]pyrano[3, 2-h]acridin-7-one analogues of acronycine.

P. Renard, B. Pfeiffer, F. Tillequin, 2000, Journal of medicinal chemistry.

3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.

P. Renard, D. Caignard, B. Pfeiffer, 1994, Journal of medicinal chemistry.

Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.

P. Renard, B. Pfeiffer, S. Gallet, 2009, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline receptor selective ligand with hypotensive activity.

P. Renard, B. Pfeiffer, S. Schann, 2001, Journal of medicinal chemistry.

Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 1. Synthesis and biological activities of N-benzyl-N'-(arylalkyl)-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines .

G. Dive, P. Renard, B. Pfeiffer, 1997, Journal of medicinal chemistry.

Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro.

B. Pfeiffer, B. Lockhart, M. Largeron, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and cytotoxic activity of dimeric analogs of acronycine in the benzo[b]pyrano[3,2-h]acridin-7-one series.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2007, Chemical & pharmaceutical bulletin.

Synthesis, biological activity and quantitative structure-activity relationships of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives

M. Rettori, B. Pfeiffer, C. Marot, 1996 .

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione.

B. Pfeiffer, M. Prudhomme, R. Golsteyn, 2006, European journal of medicinal chemistry.

Synthesis and biological activities of indolocarbazoles bearing amino acid residues.

C. Bailly, M. Sancelme, B. Pfeiffer, 2001, European journal of medicinal chemistry.

Synthesis and biological activities of isogranulatimide analogues.

C. Bailly, B. Pfeiffer, J. Hickman, 2007, Bioorganic & medicinal chemistry.

News naphtylethylurees naphtylethylthiourees and their process for the preparation and pharmaceutical compositions containing them.

P. Depreux, D. Lesieur, P. Renard, 1991 .

Cytotoxic Bis-3,4-dihydro-β-carbolines and Bis-β-carbolines

P. Renard, B. Pfeiffer, J. Sapi, 2002 .

Synthesis and cytotoxic activity of benzo[a]acronycine and benzo[b]acronycine substituted on the A ring.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2011, European journal of medicinal chemistry.

Synthesis and cytotoxic activity of psorospermin and acronycine analogues in the 3-propyloxy-acridin-9(10H)-one and -benzo[b]acridin-125H-one series.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2010, European journal of medicinal chemistry.

Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2009, Bioorganic & medicinal chemistry.

Structure-activity relationships in the acronycine and benzo[b]acronycine series: role of the pyran ring.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2008, European journal of medicinal chemistry.

Synthesis, cytotoxic activity, and mechanism of action of furo[2,3-c]acridin-6-one and benzo[b]furo[3,2-h]acridin-6-one analogues of psorospermin and acronycine.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2008, Journal of medicinal chemistry.

Synthesis and cytotoxic activity of acronycine analogues in the benzo[c]pyrano[3,2-h]acridin-7-one and naphtho[1,2-b][1,7] and [1,10]-phenanthrolin-7(14H)-one series.

B. Pfeiffer, J. Bongui, F. Tillequin, 2005, Chemical & pharmaceutical bulletin.

Design, synthesis, and cytotoxic activity of Michael acceptors and enol esters in the benzo[b]acronycine series.

C. Bailly, B. Pfeiffer, F. Tillequin, 2005, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine.

B. Pfeiffer, F. Tillequin, Hanh Trinh-van-Dufat, 2004, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxic and antitumor activity of 1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine diacid hemiesters and carbamates.

P. Renard, B. Pfeiffer, F. Tillequin, 2004, Chemical & pharmaceutical bulletin.

Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Journal of medicinal chemistry.

Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors.

B. Pfeiffer, J. Hickman, F. Tillequin, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

New carboxylic acid derivatives of 7-oxo-2,3,7,14- tetrahydro-1H-benzo [b] pyrano [3,2 h] acridine, their process for the preparation and pharmaceutical compositions containing them

P. Renard, B. Pfeiffer, F. Tillequin, 1999 .

Asymmetric synthesis of a conformationally constrained N-phosphonoalkyl dipeptide

B. Pfeiffer, G. Tucker, J. Royer, 1997 .

Efficient selective synthesis of 2-substituted indoles from complex-base-promoted arynic cyclisations

P. Renard, B. Pfeiffer, P. Caubére, 1997 .

Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.

C. Bailly, P. Colson, P. Renard, 2004, Journal of medicinal chemistry.

Design, synthesis and evaluation of new 6-substituted-5-benzyloxy-4-oxo-4H-pyran-2-carboxamides as potential Src inhibitors

B. Pfeiffer, C. Logé, F. Cruzalegui, 2008 .

Cytotoxic turrianes of Kermadecia elliptica from the New Caledonian rainforest.

B. Pfeiffer, M. Litaudon, V. Dumontet, 2008, Phytochemistry.

Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.

P. Depreux, D. Lesieur, P. Renard, 1998, Journal of medicinal chemistry.

Novel naphthalenic ligands with high affinity for the melatonin receptor.

D. Lesieur, P. Renard, B. Pfeiffer, 1992, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of novel arylalkyl 4-benzyl piperazine derivatives as sigma site selective ligands.

P. Renard, M. Rettori, B. Pfeiffer, 2000, European journal of medicinal chemistry.

Synthesis and analgesic evaluation of some 1,1-disubstituted 3-carboxy-4-phenyl-1,2,3,4-tetrahydro-β-carboline derivatives

P. Renard, B. Pfeiffer, L. Jeannin, 1995 .

Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via palladium-catalyzed intramolecular arylation

P. Renard, B. Pfeiffer, P. Pinson, 2004 .

New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization.

P. Renard, B. Pfeiffer, S. Rault, 2003, Journal of medicinal chemistry.

Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.

P. Renard, B. Pfeiffer, C. Monneret, 2005, Journal of medicinal chemistry.

6-aminoalkyloxazolo[4,5-b]pyridin-2(3H)-ones: synthesis and evaluation of antinoceptive activity.

P. Renard, B. Pfeiffer, G. Guillaumet, 1998, Bioorganic & medicinal chemistry.

A Convenient Synthesis of 5‐Arylamino‐4H‐pyran‐4‐ones Using Palladium‐Catalyzed Amination.

B. Pfeiffer, C. Logé, B. Lesur, 2010 .

First tricyclic oximino derivatives as 5-HT3 ligands.

P Delagrange, P. Renard, B. Pfeiffer, 2001, Bioorganic & medicinal chemistry letters.

Substituted 3-amino and/or 3-aminomethyl-3,4-dihydro-2H-1-benzopyrans: synthesis and biological activity.

P. Renard, M. Rettori, B. Pfeiffer, 2000, Bioorganic & medicinal chemistry.

N,N-disubstituted aminomethyl benzofuran derivatives: synthesis and preliminary binding evaluation.

P. Renard, M. Rettori, B. Pfeiffer, 1999, Bioorganic & medicinal chemistry.

Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.

B. Pfeiffer, M. Prudhomme, S. Messaoudi, 2005, European journal of medicinal chemistry.

Respective contributions of α‐adrenergic and non‐adrenergic mechanisms in the hypotensive effect of imidazoline‐like drugs

J. Boutin, P. Renard, B. Pfeiffer, 2001, British journal of pharmacology.

Synthesis and cytotoxic activity of benzophenanthrolinone analogues of acronycine.

P. Renard, B. Pfeiffer, J. Bongui, 2001, Chemical and pharmaceutical bulletin.

Synthesis and cytotoxic activity of benzo[a]pyrano[3,2-h] and [2,3-i]xanthone analogues of psorospermine, acronycine, and benzo[a]acronycine.

B. Pfeiffer, F. Tillequin, S. Boutefnouchet, 2006, Chemical & pharmaceutical bulletin.

Structure–activity relationships and structural conformation of a novel urotensin II-related peptide

Hassan Oulyadi, Pierre Renard, Jérôme Leprince, 2004, Peptides.

Structure–Activity Relationships of Human Urotensin II and Related Analogues on Rat Aortic Ring Contraction

Pierre Renard, Jérôme Leprince, Hubert Vaudry, 2003, Journal of enzyme inhibition and medicinal chemistry.

Psychopharmacological profile of a new chroman derivative with 5‐hydroxytryptamine1A agonist properties: S 20499 (+)

R. Porsolt, B. Pfeiffer, D. Caignard, 1992 .

Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents.

P. Renard, B. Pfeiffer, S. Léonce, 2000, Bioorganic & medicinal chemistry letters.

Design of new anticancer drugs. II. Easy arynic access to benzocyclobutacarbazoles, a new family of antitumor agents

P. Renard, B. Pfeiffer, P. Caubére, 1998 .

Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes.

P. Renard, B. Pfeiffer, A. Lamouri, 1996, The Journal of pharmacology and experimental therapeutics.

A novel series of 2,6,7-substituted 2,3-dihydro-1,4-benzodioxin and 2,6,7-substituted 1,4-benzodioxin derivatives as lipid peroxidation inhibitors. Structure-activity relationships for high inhibition of human low-density lipoprotein peroxidation.

P. Renard, B. Pfeiffer, G. Guillaumet, 2001, Journal of Medicinal Chemistry.

Synthesis and Structure−Activity Relationships of New 1,3-Disubstituted Cyclohexanes as Structurally Rigid Leukotriene B4 Receptor Antagonists

P. Renard, B. Pfeiffer, J. Girard, 1999 .

Expeditious Synthesis and Cytotoxic Activity of New Cyanoindolo[3,2‐c]quinolines and Benzimidazo[1,2‐c]quinazolines.

P. Renard, B. Pfeiffer, G. Guillaumet, 2000 .

Tröger’s bases in the acronycine, benzo[a]acronycine, and benzo[b]acronycine series

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2011 .

Synthesis, antitumor activity, and mechanism of action of benzo[a]pyrano[3,2-h]acridin-7-one analogues of acronycine.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2006, Journal of Medicinal Chemistry.

Effects of S-21007, a potent 5-HT3 partial agonist, in mouse anxiety.

P. Renard, B. Pfeiffer, S. Rault, 1999, Zhongguo yao li xue bao = Acta pharmacologica Sinica.

Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production.

C. Sarrauste de Menthière, P. Renard, B. Pfeiffer, 2004, European journal of medicinal chemistry.

Insulin-like partial effects of agmatine derivatives in adipocytes.

B. Pfeiffer, G. Weitzel, W. Stock, 1980, Hoppe-Seyler´s Zeitschrift für physiologische Chemie.

Interaction of S 21007 with 5-HT3 receptors. In vitro and in vivo characterization.

M. Hamon, P. Renard, B. Pfeiffer, 1996, European journal of pharmacology.

Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle

P. Renard, B. Pfeiffer, B. Hugon, 2003 .

Dimers from dechlorinated rebeccamycin: synthesis, interaction with DNA, and antiproliferative activities.

C. Bailly, P. Renard, B. Pfeiffer, 2002, European journal of medicinal chemistry.

Syntheses and antiproliferative activities of new rebeccamycin derivatives with the sugar unit linked to both indole nitrogens.

P. Renard, B. Pfeiffer, M. Prudhomme, 2002, Journal of medicinal chemistry.

[Insulin-like effects of agmatine derivatives in vitro and in vivo (author's transl)].

B. Pfeiffer, G. Weitzel, W. Sarrazin, 1981, Hoppe-Seyler´s Zeitschrift für physiologische Chemie.

Synthesis of the Naphthalenic Bioisostere of the Anti-Migraine Drug Sumatriptan

P. Depreux, D. Lesieur, B. Pfeiffer, 1995 .

5‐Substituted 3,4‐dihydro‐3‐amino‐2H‐1‐benzopyran derivatives: synthesis and interaction with serotoninergic receptors

P. Renard, B. Pfeiffer, P. Delagrange, 2001, The Journal of pharmacy and pharmacology.

N-substituted aminohydroxypyridines as potential non-opioid analgesic agents.

P. Renard, B. Pfeiffer, G. Guillaumet, 1995, Bioorganic & medicinal chemistry.

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

B. Pfeiffer, S. Rault, F. Lezoualc’h, 2009, Bioorganic & medicinal chemistry.

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells.

B. Pfeiffer, J. Hickman, R. Golsteyn, 2010, Cancer letters.

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

G. Ferry, J. Boutin, B. Pfeiffer, 2011, Life sciences.

Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines.

Sylvain Rault, Philippe Delagrange, M. Hamon, 1996, Journal of medicinal chemistry.