S. Dabbs

发表

Novel and selective 5-HT2C/2B receptor antagonists as potential anxiolytic agents: synthesis, quantitative structure-activity relationships, and molecular modeling of substituted 1-(3-pyridylcarbamoyl)indolines.

S. Bromidge, S. Dabbs, D. Davies, 1998, Journal of medicinal chemistry.

A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970).

P J Lovell, J. Hagan, D. Middlemiss, 2000, Journal of medicinal chemistry.

Flexible palladium-catalysed amidation reactions for the synthesis of complex aryl amides

S. Dabbs, D. Davies, R. Markwell, 2010 .

Synthesis, Biological Activity, and Molecular Modeling Studies of Selective 5‐HT2C/2B Receptor Antagonists.

Frank E. Blaney, S. Dabbs, D. Duckworth, 1997 .

Synthesis, biological activity, and molecular modeling of selective 5-HT(2C/2B) receptor antagonists.

S. Dabbs, D. Duckworth, I. Forbes, 1996, Journal of medicinal chemistry.

(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.

P J Lovell, J. Hagan, A. Brown, 1998, Journal of medicinal chemistry.

Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent.

D. Middlemiss, S. Lightowler, S. Bromidge, 2000, Journal of medicinal chemistry.

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, E. Minthorn, 2016, Bioorganic & medicinal chemistry letters.

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, E. Minthorn, 2013, Bioorganic & medicinal chemistry letters.

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, Susanne Eyrisch, 2011, Bioorganic & medicinal chemistry letters.

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, T. Gallagher, 2011, Bioorganic & medicinal chemistry letters.

Pseudohalogen chemistry. XI. Some aspects of the chemistry of α-thiocyanato-β-dicarbonyl compounds

S. Dabbs, P. Mountford, R. G. Guy, 1994 .

5-Hydroxytryptamine (5-HT3) receptor antagonists. 2. 1-Indolinecarboxamides.

S. Dabbs, F. King, J. Bermudez, 1990, Journal of medicinal chemistry.

The design of efficient and selective routes to pyridyl analogues of 2,3-dihydro-1,4-benzodioxin-6-carbaldehyde

S. Dabbs, D. Davies, Christopher W. Barfoot, 2010 .

A novel and selective class of azabicyclic muscarinic agonists incorporating an N-methoxy imidoyl halide or nitrile functionality

S. Bromidge, S. Dabbs, G. Riley, 1992 .

5-Hydroxytryptamine (5-HT3) receptor antagonists. 3. Ortho-substituted phenylureas.

S. Dabbs, F. King, J. Bermudez, 1990, Journal of medicinal chemistry.

1,2,5,6-tetrahydropyridine oxime ethers incorporating electron withdrawing groups are potent and selective muscarinic agonists

S. Bromidge, S. Dabbs, G. Riley, 1994 .

Design and synthesis of azabicyclic muscarinic agonists incorporating an oxime ether functionality

S. Bromidge, S. Dabbs, G. Riley, 1992 .

Model studies on a synthetically facile series of N-substituted phenyl-N'-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT(2C/2B) receptor antagonists.

S. Bromidge, S. Dabbs, D. Davies, 1999, Bioorganic & medicinal chemistry.