J. Vendôme

发表

Two-step adhesive binding by classical cadherins

B. Honig, L. Shapiro, F. Bahna, 2010, Nature Structural &Molecular Biology.

Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT

Yong Zi Tan, P. Roepe, D. Fidock, 2019, Nature.

Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins

Fabiana Bahna, Barry Honig, Lawrence Shapiro, 2011, Nature Structural &Molecular Biology.

In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas

J. Sacchettini, J. Vendôme, V. Feher, 2022, Journal of medicinal chemistry.

The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.

B. Honig, J. Frank, Soonjin Hong, 2011, Structure.

Induced-Fit Docking Enables Accurate Free Energy Perturbation Calculations in Homology Models.

R. Friesner, K. Borrelli, Kai Zhu, 2022, Journal of chemical theory and computation.

LYMPHOID NEOPLASIA Silencing c-Myc translation as a therapeutic strategy through targeting PI3K d and CK1 « in hematological malignancies

B. Honig, N. Tatonetti, J. Vendôme, 2016 .

Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.

J. Vendôme, M. Michino, C. Nathan, 2022, Journal of medicinal chemistry.

Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's Disease.

O. Arancio, J. Vendôme, D. Landry, 2017, Journal of medicinal chemistry.

Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation

B. Rost, E. Kloppmann, L. Shapiro, 2016, Science.

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

M. Eppstein, P. Roepe, D. Fidock, 2022, PLoS pathogens.

T-cadherin structures reveal a novel adhesive binding mechanism

B. Honig, T. Jessell, L. Shapiro, 2010, Nature Structural &Molecular Biology.

Silencing c-Myc Translation As a Therapeutic Strategy through Targeting PI3K Delta and CK1 Epsilon in Hematological Malignancies

B. Honig, N. Tatonetti, J. Vendôme, 2016 .

Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers

B. Honig, L. Shapiro, F. Bahna, 2011, Proceedings of the National Academy of Sciences.

Linking molecular affinity and cellular specificity in cadherin-mediated adhesion

L Shapiro, B. Honig, T. Jessell, 2009, Proceedings of the National Academy of Sciences.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

M. Foley, P. Rosenthal, P. Bhanot, 2018, Proceedings of the National Academy of Sciences.

Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis

J. Sacchettini, T. Ioerger, J. Vendôme, 2018, ACS infectious diseases.

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.

B. Honig, N. Tatonetti, J. Vendôme, 2017, Blood.

Characterization of Biochemical Properties of Bacillus subtilis RecQ Helicase

J. Vendôme, X. Xi, E. Bugnard, 2014, Journal of bacteriology.

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

Wael E Houssen, J. Naismith, J. Vendôme, 2012, Nature Structural &Molecular Biology.

Splice Form Dependence of β-Neurexin/Neuroligin Binding Interactions

B. Honig, L. Shapiro, F. Bahna, 2010, Neuron.

Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.

M. Foley, J. Vendôme, N. Liverton, 2023, Journal of medicinal chemistry.

The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides

J. Naismith, J. Vendôme, M. Jaspars, 2012, Chembiochem : a European journal of chemical biology.

Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP

J. Vendôme, N. Westwood, Brunello Nardone, 2016, Chembiochem : a European journal of chemical biology.

Fine sampling of sequence space for membrane protein structural biology.

W. Hendrickson, J. Vendôme, F. Mancia, 2021, Journal of molecular biology.

Transforming binding affinities from 3D to 2D with application to cadherin clustering

Yinghao Wu, Barry Honig, Lawrence Shapiro, 2011, Nature.

Nectin ectodomain structures reveal a canonical adhesive interface

B. Honig, Soonjin Hong, L. Shapiro, 2012, Nature Structural &Molecular Biology.

Structural and energetic determinants of adhesive binding specificity in type I cadherins

Julia Brasch, Fabiana Bahna, Barry Honig, 2014, Proceedings of the National Academy of Sciences.

Enhancing Hit Discovery in Virtual Screening through Absolute Protein-Ligand Binding Free-Energy Calculations.

R. Friesner, J. Vendôme, Robert Abel, 2023, Journal of chemical information and modeling.

Loop L5 Acts as a Conformational Latch in the Mitotic Kinesin Eg5*

B. Honig, S. Rosenfeld, J. Vendôme, 2010, The Journal of Biological Chemistry.

Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti-malaria activity in humanized mice.

P. Rosenthal, J. Vendôme, M. Michino, 2021, Angewandte Chemie.

Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.

M. Foley, Huilin Li, J. Vendôme, 2021, Journal of medicinal chemistry.

Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform

Yong Zi Tan, P. Roepe, D. Fidock, 2019 .