H. Döppler

发表

Functional dichotomy of A20 in apoptotic and necrotic cell death.

A. Toker, P. Storz, H. Döppler, 2005, The Biochemical journal.

Foxo3a drives proliferation in anaplastic thyroid carcinoma through transcriptional regulation of cyclin A1: a paradigm shift that impacts current therapeutic strategies

Peter Storz, David O Azorsa, J. Copland, 2012, Journal of Cell Science.

Protein Kinase D Mediates Mitochondrion-to-Nucleus Signaling and Detoxification from Mitochondrial Reactive Oxygen Species

Peter Storz, A. Toker, P. Storz, 2005, Molecular and Cellular Biology.

TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells

G. Müller, P. Storz, H. Döppler, 2000, Cell Death and Differentiation.

Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.

G. Müller, A. Wernig, P. Storz, 1999, European journal of biochemistry.

TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28

G. Müller, A. Wernig, P. Storz, 1998, FEBS letters.

Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs

B. Necela, M. Raimondo, P. Storz, 2013, The Journal of cell biology.

Generation of Hydrogen Peroxide and Downstream Protein Kinase D1 Signaling Is a Common Feature of Inducers of Pancreatic Acinar-to-Ductal Metaplasia

P. Storz, H. Döppler, G. Liou, 2022, Antioxidants.

Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.

B. Necela, P. Storz, H. Döppler, 2015, Cancer discovery.

Activation Loop Phosphorylation Controls Protein Kinase D-Dependent Activation of Nuclear Factor κB

A. Toker, P. Storz, H. Döppler, 2004, Molecular Pharmacology.

Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity

P. Storz, H. Döppler, G. Liou, 2013, PloS one.

A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells

P. Storz, H. Döppler, Sahra Borgés, 2014, Breast Cancer Research and Treatment.

Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4.

P. Storz, H. Döppler, N. Durand, 2013, The Biochemical journal.

Regulation of VASP by phosphorylation

P. Storz, H. Döppler, Heike R. Döppler, 2013, Cell adhesion & migration.

Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling.

A. Toker, P. Storz, H. Döppler, 2004, Molecular and cellular biology.

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

B. Turk, P. Storz, H. Döppler, 2017, Scientific Reports.

Tumor Necrosis Factor Induces Ceramide Oscillations and Negatively Controls Sphingolipid Synthases by Caspases in Apoptotic Kym-1 Cells*

G. Müller, H. Döppler, K. Pfizenmaier, 1998, The Journal of Biological Chemistry.

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

D. Radisky, P. Storz, H. Döppler, 2015, Nature Communications.

Ym1+ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer

P. Storz, H. Döppler, G. Liou, 2022, iScience.

The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis.

N. Bardeesy, P. Storz, H. Döppler, 2017, Cell reports.

Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ

P. Storz, H. Döppler, K. Ling, 2016, Scientific Reports.

Sangivamycin and its derivatives inhibit Haspin-Histone H3-survivin signaling and induce pancreatic cancer cell death

Elizabeth M. Reid, P. Storz, H. Döppler, 2019, Scientific Reports.

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis

E. Perez, E. Thompson, Zhifu Sun, 2013, Breast Cancer Research.

Protein Kinase C Selectively Regulates Protein Kinase D-Dependent Activation of NF- B in Oxidative Stress Signaling

A. Toker, P. Storz, H. Döppler, 2004 .

Loss of cell–cell contacts induces NF‐κB via RhoA‐mediated activation of protein kinase D1

P. Storz, H. Döppler, I. Yan, 2009, Journal of cellular biochemistry.

Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion

S. Goodison, P. Storz, H. Döppler, 2009, Breast Cancer Research.

Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.

P. Storz, H. Döppler, M. Leitges, 2016, Cell reports.

Mitochondrial and Oxidative Stress-Mediated Activation of Protein Kinase D1 and Its Importance in Pancreatic Cancer

P. Storz, H. Döppler, Heike R. Döppler, 2017, Front. Oncol..

The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer

Elizabeth M. Reid, P. Storz, H. Döppler, 2016, Scientific Reports.

Tyrosine Phosphorylation of Protein Kinase D in the Pleckstrin Homology Domain Leads to Activation*

A. Toker, P. Storz, H. Döppler, 2003, The Journal of Biological Chemistry.

Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex

P. Storz, H. Döppler, Ligia I. Bastea, 2012, PloS one.

Protein Kinase D Isoforms Differentially Modulate Cofilin-Driven Directed Cell Migration

P. Storz, H. Döppler, Sahra Borgés, 2014, PloS one.

Regulation of novel protein kinase C ε by phosphorylation

A. Newton, A. Toker, H. Döppler, 2002 .

Protein Kinase D1 regulates Cofilin mediated F-actin reorganization and cell motility via Slingshot

P. Storz, H. Döppler, I. Yan, 2009, Nature Cell Biology.

Regulation of Raf‐1 kinase by TNF via its second messenger ceramide and cross‐talk with mitogenic signalling

G. Müller, W. Kolch, H. Mischak, 1998, The EMBO journal.

A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression.

B. Groner, G. Müller, P. Storz, 1999, Analytical biochemistry.

Neuregulin Mediates F-actin-driven Cell Migration through Inhibition of Protein Kinase D1 via Rac1 Protein*

P. Storz, H. Döppler, T. Eiseler, 2012, The Journal of Biological Chemistry.

Insulin selectively activates STAT5b, but not STAT5a, via a JAK2‐independent signalling pathway in Kym‐1 rhabdomyosarcoma cells

G. Müller, P. Storz, H. Döppler, 1999, FEBS letters.

Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4*

P. Storz, H. Döppler, K. Mizuno, 2011, The Journal of Biological Chemistry.

A Novel Tyrosine Phosphorylation Site in Protein Kinase D Contributes to Oxidative Stress-mediated Activation*

P. Storz, H. Döppler, Heike R. Döppler, 2007, Journal of Biological Chemistry.

A Phosphorylation State-specific Antibody Recognizes Hsp27, a Novel Substrate of Protein Kinase D*

A. Toker, P. Storz, H. Döppler, 2005, Journal of Biological Chemistry.

The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast

E. Thompson, P. Storz, H. Döppler, 2018, Oncotarget.

FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases

A. Toker, J. Copland, P. Storz, 2009, Molecular and Cellular Biology.

Regulation of novel protein kinase C epsilon by phosphorylation.

A. Newton, A. Toker, H. Döppler, 2002, The Biochemical journal.

Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

P. Storz, H. Döppler, I. Yan, 2009, Journal of Cell Science.

Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion

P. Storz, H. Döppler, N. Durand, 2017, Scientific Reports.

The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma

P. Storz, H. Döppler, X. Geiger, 2015, Oncotarget.

Protein Kinase D1-mediated Phosphorylations Regulate Vasodilator-stimulated Phosphoprotein (VASP) Localization and Cell Migration*

P. Storz, H. Döppler, P. Anastasiadis, 2013, The Journal of Biological Chemistry.

Differences in Metabolic Programming Define the Site of Breast Cancer Cell Metastasis.

P. Storz, H. Döppler, Heike R. Döppler, 2015, Cell metabolism.

Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells

T. Patel, P. Storz, H. Döppler, 2021, iScience.