Osmar Norberto de Souza

发表

Mining flexible-receptor docking experiments to select promising protein receptor snapshots

Ana T. Winck, K. Machado, A. T. Winck, 2010, BMC Genomics.

Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function

J. Joung, X. Breakefield, Osmar Norberto de Souza, 2020, Molecular therapy. Nucleic acids.

Rethinking the MtInhA tertiary and quaternary structure flexibility: a molecular dynamics view

Osmar Norberto de Souza, L. A. Basso, L. F. Saraiva Macedo Timmers, 2022, Journal of Molecular Modeling.

An Effective Approach for Clustering InhA Molecular Dynamics Trajectory Using Substrate-Binding Cavity Features

Duncan D. A. Ruiz, Renata De Paris, Osmar Norberto de Souza, 2015, PloS one.

Evaluation of drug repositioning by molecular docking of pharmaceutical resources available in the Brazilian healthcare system against SARS-CoV-2

Osmar Norberto de Souza, R. Ligabue-Braun, J. D. da Costa, 2021, Informatics in Medicine Unlocked.

Evaluation of the impact of functional diversification on Poaceae, Brassicaceae, Fabaceae, and Pinaceae alcohol dehydrogenase enzymes

F. Salzano, Osmar Norberto de Souza, C. Thompson, 2010, Journal of molecular modeling.

A Network Flow Approach to Predict Protein Targets and Flavonoid Backbones to Treat Respiratory Syncytial Virus Infection

D. Bonatto, Osmar Norberto de Souza, Joice de Faria Poloni, 2015, BioMed research international.

Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis

Osmar Norberto de Souza, A. Mascarello, R. Nunes, 2018, PloS one.

Conformational changes in 2-trans-enoyl-ACP (CoA) reductase (InhA) from M. tuberculosis induced by an inorganic complex: a molecular dynamics simulation study

C. Zhan, Osmar Norberto de Souza, Ivani Pauli, 2012, Journal of Molecular Modeling.

Missense mutations in DYT-TOR1A dystonia

I. Skogseid, Z. Iqbal, M. Toft, 2019, Neurology: Genetics.

EPSP synthase flexibility is determinant to its function: computational molecular dynamics and metadynamics studies

Osmar Norberto de Souza, L. A. Basso, D. Santos, 2017, Journal of Molecular Modeling.

FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection

Karina S Machado, Osmar Norberto de Souza, K. Machado, 2011, BMC Genomics.

Effect of the explicit flexibility of the InhA enzyme from Mycobacterium tuberculosis in molecular docking simulations

Karina S Machado, Osmar Norberto de Souza, K. Machado, 2011, BMC Genomics.