C. Morton

Michael W Parker, Vi Pham, David B Ascher, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification and characterization of a new cognitive enhancer based on inhibition of insulinâ•’regulated aminopeptidase

C. Morton, S. Ye, D. Ascher, 2008 .

Calorimetric and structural studies of the nitric oxide carrier S‐nitrosoglutathione bound to human glutathione transferase P1‐1

M. Parker, C. Morton, J. Adams, 2006, Protein Science.

472. Aromatic polyfluoro-compounds. Part XXIII. Polyfluoroazo, -azoxy-, and -hydrazo-benzenes

C. Morton, J. Burdon, D. F. Thomas, 1965 .

Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase.

Michael W Parker, David B Ascher, M. Parker, 2008, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Molecular Evolution of Glutathione S-Transferases in the Genus Drosophila

W. Low, P. Batterham, C. Robin, 2007, Genetics.

Excited-state deprotonation of 2-naphthol by anions

C. Morton, A. M. Halpern, C. Marzzacco, 1991 .

Modified Friedel-Crafts Preparation of 2,2,4,4-Tetrachloro-6,6-diphenylcyclotriphosphazatriene

C. Morton, K. Okuhara, E. Mcbee, 1965 .

Glutathione transferase P1‐1 as an arsenic drug‐sequestering enzyme

M. Parker, C. Morton, A. Bocedi, 2017, Protein science : a publication of the Protein Society.

Reactions of Hexachloro- and 2,2,4,4-Tetrachloro-6,6-diphenylcyclotriphosphazatrienes with Sodium Phenoxide

C. Morton, K. Okuhara, E. Mcbee, 1966 .

Reaction of Amines with Cyclic Fluorinated Olefins1,2

C. Morton, J. J. Turner, E. Mcbee, 1965 .

Tetrachlorocyclopentadienylidene and Thermal Rearrangements of Its Cyclopropyl Adducts1

C. Morton, E. Mcbee, J. A. Bosoms, 1966 .

Water mediated protein‐DNA interactions: The relationship of thermodynamics to structural detail

J. Ladbury, C. Morton, 1996, Protein science : a publication of the Protein Society.

Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.

C. Morton, W. Rawlinson, G. Scott, 2005, The Journal of general virology.

A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1

M. Parker, C. Morton, C. Rodolfo, 2019, Proceedings of the National Academy of Sciences.

Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.

M. Parker, C. Morton, S. Feil, 2016, Structure.

An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin

M. Parker, C. Morton, R. Tweten, 2015, Proceedings of the National Academy of Sciences.

Cholesterol-Dependent Cytolysins: Membrane and Protein Structural Requirements for Pore Formation.

M. Parker, C. Morton, F. Separovic, 2019, Chemical reviews.

The genetics, structure and function of the M1 aminopeptidase oxytocinase subfamily and their therapeutic potential in immune-mediated disease.

M. Parker, C. Morton, T. Kenna, 2019, Human immunology.

Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA

Jerome Wielens, David B. Ascher, Michael W. Parker, 2014, Scientific Reports.

Synthesis and reactions of some highly chlorinated azobenzenes

C. Morton, E. P. Wesseler, E. Mcbee, 1972 .

Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.

R. Cherny, M. Parker, C. Morton, 2011, Biochemistry.

Insights into Interactions between the α-Helical Region of the Salmon Calcitonin Antagonists and the Human Calcitonin Receptor using Photoaffinity Labeling*

P. Sexton, M. Parker, C. Morton, 2005, Journal of Biological Chemistry.

Cholesterol-dependent cytolysins: from water-soluble state to membrane pore

M. Parker, C. Morton, M. Christie, 2018, Biophysical Reviews.

Genetic Variants in ERAP1 and ERAP2 Associated With Immune‐Mediated Diseases Influence Protein Expression and the Isoform Profile

M. Brown, C. Morton, U. Oppermann, 2018, Arthritis & rheumatology.

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

W. Low, P. Batterham, C. Robin, 2010, Journal of molecular biology.

A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins

M. Parker, C. Morton, M. Christie, 2020, mBio.

X-ray crystallography shines a light on pore-forming toxins.

M. Parker, C. Morton, M. Christie, 2021, Methods in enzymology.

From glutathione transferase to pore in a CLIC

M. Parker, C. Morton, B. Cromer, 2002, European Biophysics Journal.

Solution structure of synthetic peptides corresponding to the C-terminal helix of interleukin-6.

R. Norton, C. Morton, R. Simpson, 1994, European journal of biochemistry.

NMR studies of the solution properties of recombinant murine interleukin-6.

J. G. Zhang, R. Norton, C. Morton, 1995, Biochimica et biophysica acta.

Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site

B. Kemp, M. Parker, C. Morton, 2004 .

An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.

F. Helmstetter, G. Ecker, W. Sieghart, 2007, Current medicinal chemistry.

The role of Rdl in resistance to phenylpyrazoles in Drosophila melanogaster.

P. Batterham, M. Parker, C. Morton, 2014, Insect biochemistry and molecular biology.

The biological function of an insect antifreeze protein simulated by molecular dynamics

C. Morton, Angus A. Gray-Weale, M. Kuiper, 2015, eLife.

A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein

S. Baratchi, K. Peter, T. Nero, 2022, EMBO molecular medicine.

Structural biology of cell surface receptors implicated in Alzheimer’s disease

T. Nero, M. Parker, C. Morton, 2021, Biophysical Reviews.

Solution Structure of the Link Module: A Hyaluronan-Binding Domain Involved in Extracellular Matrix Stability and Cell Migration

I. Campbell, C. Morton, D. Kohda, 1996, Cell.

Functional and structural analysis of cytokine selective IL6ST defects that cause recessive hyper-IgE syndrome.

Diane B. Zastrow, E. Ashley, M. Wheeler, 2021, The Journal of allergy and clinical immunology.

Novel Therapeutic Approaches to Treat Alzheimer's Disease and Memory Disorders

David B. Ascher, Michael W. Parker, Craig J. Morton, 2008 .

Crystal structure of human insulin‐regulated aminopeptidase with specificity for cyclic peptides

M. Parker, C. Morton, J. Holien, 2015, Protein science : a publication of the Protein Society.

Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.

I D Campbell, I. Campbell, M. Waterfield, 1996, Biochemistry.

Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases.

T. Nero, C. Morton, J. Kiefer, 2022, Pharmacology & therapeutics.

Probing the nature of interactions in SH2 binding interfaces–evidence from electrospray ionization mass spectrometry

C. Robinson, J. Ladbury, C. Morton, 1999, Protein science : a publication of the Protein Society.

The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.

I. Campbell, C. Morton, T. Mulhern, 1997, Structure.

Hsp90 increases LIM kinase activity by promoting its homo‐dimerization

A. Citri, Y. Yarden, M. Parker, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

M. Parker, C. Morton, S. Feil, 2015, Scientific Reports.

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

M. Dottore, Angel F. Lopez, T. Nero, 2018, Nature Communications.

Hormone Receptor Mechanism of Activation of Protein Kinase JAK 2 by the Growth

Mara, Guillermo A. Gomez, I. Wilson, 2014 .

Role of the C‐terminus in the activity, conformation, and stability of interleukin‐6

L. D. Ward, R. Norton, C. Morton, 1993, Protein science : a publication of the Protein Society.

S-7 : A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor

Guillermo A. Gomez, A. Mark, M. Doxastakis, 2014 .

Discovery of Phosphodiesterase-4 Inhibitors: Serendipity and Rational Drug Design

M. Parker, C. Morton, S. Feil, 2014 .

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

M. Parker, C. Morton, S. Panjikar, 2019, mBio.

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

Jennifer L. Martin, C. Morton, M. Scanlon, 2015, Acta crystallographica. Section D, Biological crystallography.

SH3 Domains: Molecular ‘Velcro’ 1

I. D. Campbell, I. Campbell, C. Morton, 1994, Current Biology.

An Intermolecular π-Stacking Interaction Drives Conformational Changes Necessary to β-Barrel Formation in a Pore-Forming Toxin

M. Parker, C. Morton, R. Tweten, 2019, mBio.

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins.

J. Rossjohn, M. Parker, C. Morton, 2007, Journal of molecular biology.

Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome

E. Winzeler, L. Tilley, D. Fidock, 2021, Proceedings of the National Academy of Sciences.

Insights into the Structural Basis for Zinc Inhibition of the Glycine Receptor*

M. Parker, C. Morton, J. Lynch, 2003, Journal of Biological Chemistry.

Solid-state NMR structure determination of melittin in a lipid environment.

C. Morton, S. Wassall, F. Separovic, 2001, Biophysical journal.

Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands*

Arthur Christopoulos, Patrick M Sexton, Michael W Parker, 2007, Journal of Biological Chemistry.

Solution structure and peptide binding of the SH3 domain from human Fyn.

I D Campbell, I. Campbell, E. Brown, 1996, Structure.

Structure and Function of the Proteasome Activator PA28 of the Malaria Parasite Plasmodium falciparum

L. Tilley, M. Parker, C. Morton, 2019, Microscopy and Microanalysis.

Transitional Changes in the Structure of C-Reactive Protein Create Highly Pro-Inflammatory Molecules: Therapeutic Implications for Cardiovascular Diseases

K. Peter, T. Nero, C. Morton, 2022, SSRN Electronic Journal.

Cytoplasmic ATP-sensing Domains Regulate Gating of Skeletal Muscle ClC-1 Chloride Channels*

M. Parker, C. Morton, D. Stapleton, 2005, Journal of Biological Chemistry.

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2.

D. Manallack, M. Parker, C. Morton, 2011, Bioorganic & medicinal chemistry letters.

Effect of Linker Length on Avidin Binding to Biotinylated Gramicidin A

C. Morton, G. Talbo, R. Koeppe, 2006, International Journal of Peptide Research and Therapeutics.

Solid-state NMR conformational studies of a melittin-inhibitor complex

C. Morton, F. Separovic, Y. Lam, 2002, European Biophysics Journal.

Design of a Conformationally Defined and Proteolytically Stable Circular Mimetic of Brain-derived Neurotrophic Factor*

Jordan M Fletcher, C. Morton, R. Hughes, 2008, Journal of Biological Chemistry.

Anxiety over GABA(A) receptor structure relieved by AChBP.

Michael W Parker, M. Parker, C. Morton, 2002, Trends in biochemical sciences.

Influence of the H‐site residue 108 on human glutathione transferase P1‐1 ligand binding: Structure‐thermodynamic relationships and thermal stability

M. Parker, C. Morton, A. Primavera, 2009, Protein science : a publication of the Protein Society.

Complete amino acid sequence of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone Actinia tenebrosa.

R. Moritz, R. Norton, C. Morton, 1990, European journal of biochemistry.

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

Derek S. Tan, E. Winzeler, E. Istvan, 2023, Research Square.

Mutations in an intracellular vestibule that bifurcates from the pore of ClC-1 chloride ion channels affect anion permeation

M. Parker, C. Morton, B. Bennetts, 2020, bioRxiv.

Novel Therapeutic Approaches to Treat Alzheimer's Disease and Memory Disorders

M. Parker, C. Morton, D. Ascher, 2008 .

Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.

U. Rothlisberger, M. Parker, C. Morton, 2011, Chemistry.

An Intermolecular (cid:2) -Stacking Interaction Drives Conformational Changes Necessary to (cid:3) -Barrel Formation in a Pore-Forming Toxin

C. Morton, J. Burns, M. W. Parker, 2019 .

Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant

C. Morton, P. Gooley, K. Aizel, 2023, Nature communications.

Assembly of Fragment Screening Libraries

Martin J. Scanlon, Bradley C. Doak, Craig J. Morton, 2017 .

Phenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated Aminopeptidase

M. Parker, C. Morton, J. Holien, 2010, Molecular Pharmacology.

Identification and characterization of a new cognitive enhancer based on inhibition of insulin‐regulated aminopeptidase

C. Morton, D. Ascher, A. Albiston, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cholesterol-dependent cytolysins: from water-soluble state to membrane pore

M. Parker, C. Morton, M. Christie, 2018, Biophysical Reviews.