Dharini van der Hoeven

发表

Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding

Amit K. Gupta, C. Pagba, Priyanka Prakash, 2019, ACS omega.

Discovery of allosteric non-covalent KRAS inhibitors that bind with sub-micromolar affinity and disrupt effector binding

Amit K. Gupta, C. Pagba, Priyanka Prakash, 2018, bioRxiv.

Methods and timing of curricular integration in U.S. dental education in preparation for the Integrated National Board Dental Examination.

Dharini van der Hoeven, Lea El Hachem, Samyia Chaudhry, 2020, Journal of dental education.

A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells.

Dharini van der Hoeven, Z. Ge, J. Auchampach, 2010, Journal of molecular and cellular cardiology.

KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement

J. Frost, Amit K. Gupta, C. Pagba, 2022, ACS Bio & Med Chem Au.

A role for the low-affinity A 2B adenosine receptor in regulating superoxide generation by murine neutrophils

K. Ravid, Dharini van der Hoeven, Jordan R Van Orman, 2011 .

Activation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils.

Dharini van der Hoeven, J. Auchampach, Elizabeth T. Gizewski, 2010, Biochemical pharmacology.

Assessment of Critical Thinking in a First-Year Dental Curriculum

Dharini van der Hoeven, J. Holland, R. Quock, 2020, Medical science educator.

Fendiline Inhibits K-Ras Plasma Membrane Localization and Blocks K-Ras Signal Transmission

Dharini van der Hoeven, Kwang-jin Cho, J. Hancock, 2012, Molecular and Cellular Biology.

Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling

Michael X. Zhu, Dharini van der Hoeven, Hongzhen Hu, 2015, Science.

Nucleophosmin and Nucleolin Regulate K-Ras Plasma Membrane Interactions and MAPK Signal Transduction*

Dharini van der Hoeven, J. Hancock, K. Inder, 2009, The Journal of Biological Chemistry.

Activation of the A3 Adenosine Receptor Suppresses Superoxide Production and Chemotaxis of Mouse Bone Marrow Neutrophils

Dharini van der Hoeven, J. Auchampach, T. Wan, 2008, Molecular Pharmacology.

Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy

Travis L. Rodkey, R. Broaddus, Dharini van der Hoeven, 2013, Molecular Cancer Therapeutics.

Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane

Dharini van der Hoeven, Yong Zhou, Kwang-jin Cho, 2015, Molecular and Cellular Biology.

HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition

A. Naji, Dharini van der Hoeven, Hong Liang, 2019, EMBO reports.

Sphingomyelin Metabolism Is a Regulator of K-Ras Function

J. Frost, A. Naji, Dharini van der Hoeven, 2017, Molecular and Cellular Biology.

AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2

Priyanka Prakash, A. Gorfe, Dharini van der Hoeven, 2016, Molecular and Cellular Biology.

Inhibitors of K-Ras plasma membrane localization.

Dharini van der Hoeven, Kwang-jin Cho, J. Hancock, 2013, The Enzymes.

Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors.

J. Frost, Na Ye, Dharini van der Hoeven, 2021, European journal of medicinal chemistry.

Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function

T. Lan, Dharini van der Hoeven, J. Hancock, 2019, Life Science Alliance.

The impact of coronavirus disease 2019 pandemic on dental school assessments - Current status and future perspectives.

Dharini van der Hoeven, J. Holland, Neha Parikh, 2023, Journal of dental education.

A Role for the Low-Affinity A2B Adenosine Receptor in Regulating Superoxide Generation by Murine Neutrophils

K. Ravid, Dharini van der Hoeven, J. Auchampach, 2011, Journal of Pharmacology and Experimental Therapeutics.

Characterization of the A2B Adenosine Receptor from Mouse, Rabbit, and Dog

Dharini van der Hoeven, J. Auchampach, J. Narayanan, 2009, Journal of Pharmacology and Experimental Therapeutics.

Integration of Basic and Clinical Sciences: Student Perceptions

Dharini van der Hoeven, J. Holland, Dharini van der Hoeven, 2019, Medical science educator.

Fendiline Inhibits K-Ras Plasma Membrane Localization and Blocks K-Ras Signal Transmission

Dharini van der Hoeven, Kwang-jin Cho, J. Hancock, 2012, Molecular and Cellular Biology.