Xiaoyuan Chen

Xiaoyuan Chen, Xianzhong Zhang, 2007, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

microPET of tumor integrin alphavbeta3 expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4).

W. Cai, Xiaoyuan Chen, Zibo Li, 2007, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

microPET Imaging of tumor {alpha}v{beta}3 integrin expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4)

W. Cai, Xiaoyuan Chen, Zibo Li, 2007 .

68Ga-labeled multimeric RGD peptides for microPET imaging of integrin {alpha}v{beta}3 expression

Xiaoyuan Chen, Zibo Li, Kai Chen, 2008 .

A Thiol-Reactive 18F-Labeling Agent, N-[2-(4-18F-Fluorobenzamido)Ethyl]Maleimide, and Synthesis of RGD Peptide-Based Tracer for PET Imaging of αvβ3 Integrin Expression

Weibo Cai, Xianzhong Zhang, W. Cai, 2006 .

Integrin αvβ3 Antagonists for Anti-Angiogenic Cancer Treatment

W. Cai, V. Tse, Xiaoyuan Chen, 2007 .

64Cu-Labeled tetrameric and octameric RGD peptides for microPET imaging of tumor {alpha}v{beta}3 integrin expression

W. Cai, Xiaoyuan Chen, Zibo Li, 2007 .

A Cy5.5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice

P. Conti, Xiaoyuan Chen, R. Park, 2012, Amino Acids.

Discovery of Small Molecule Integrin αvβ3 Antagonists as Novel Anticancer Agents

Nouri Neamati, Jinxia Deng, Antonio Garofalo, 2006 .

MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide.

Ryan Park, Michel Tohme, J. Bading, 2004, Bioconjugate chemistry.

In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, and Migration After Cardiac Delivery

Sanjiv S. Gambhir, Irving L. Weissman, Manishkumar Patel, 2006, Circulation.

64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria.

Xiaoyuan Chen, Yang Zhou, Orit Jacobson, 2011, Molecular pharmaceutics.

Evaluation of 64Cu-labeled acridinium cation: a PET radiotracer targeting tumor mitochondria.

Xiaoyuan Chen, Shuang Liu, Yang Zhou, 2011, Bioconjugate chemistry.

Effects of targeting moiety, linker, bifunctional chelator, and molecular charge on biological properties of 64Cu-labeled triphenylphosphonium cations.

Xiaoyuan Chen, Zibo Li, Shuang Liu, 2008, Journal of medicinal chemistry.

Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.

N. Neamati, Xiaoyuan Chen, C. Plasencia, 2005, Journal of medicinal chemistry.

Integrin αvβ3‐targeted cancer therapy

Fan Wang, Xiaoyuan Chen, Zhaofei Liu, 2008 .

Chapter 7. Molecular imaging of tumor vasculature.

S. Gambhir, W. Cai, Xiaoyuan Chen, 2008, Methods in enzymology.

Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors

Jinming Yu, Xiaoyuan Chen, S. Yuan, 2022, Frontiers in Oncology.

Quantitative PET Imaging of Tumor Integrin αvβ3 Expression with 18F-FRGD2

S. Gambhir, W. Cai, Xiaoyuan Chen, 2006 .

Quantitative PET imaging of tumor integrin alphavbeta3 expression with 18F-FRGD2.

S. Gambhir, W. Cai, Xiaoyuan Chen, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Semiautomated Radiosynthesis and Biological Evaluation of [18F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression

S. Gambhir, Xiaoyuan Chen, P. Ray, 2008, Molecular Imaging and Biology.

Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for Monitoring Reporter Gene Expression of Wild Type and Mutant Herpes Simplex Virus Type 1 Thymidine Kinase in Cell Culture

S. Gambhir, K. Kang, J. Min, 2005, Molecular Imaging and Biology.

MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide

Peter S. Conti, Ryan Park, Michel Tohme, 2004, European Journal of Nuclear Medicine and Molecular Imaging.

Production, modification and bio-applications of magnetic nanoparticles gestated by magnetotactic bacteria

J. Xie, Xiaoyuan Chen, Kai Chen, 2009, Nano research.

Short Hairpin RNA Interference Therapy for Ischemic Heart Disease

A. Giaccia, Xiaoyuan Chen, Joseph C. Wu, 2008, Circulation.

Non-Invasive PET Imaging of EGFR Degradation Induced by a Heat Shock Protein 90 Inhibitor

W. Cai, Xiaoyuan Chen, G. Niu, 2008, Molecular Imaging and Biology.

Design and development of molecular imaging probes.

Xiaoyuan Chen, Xiaoyuan Chen, Kai Chen, 2010, Current topics in medicinal chemistry.

Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy

Weibo Cai, Hongjie Dai, H. Dai, 2008, Proceedings of the National Academy of Sciences.

Characterizing breast cancer xenograft epidermal growth factor receptor expression by using near-infrared optical imaging

Xiaoyuan Chen, B. Shen, Kai Wang, 2009, Acta radiologica.

PET of vascular endothelial growth factor receptor expression.

Sanjiv S Gambhir, Kai Chen, Weibo Cai, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In vitro and In vivo Characterization of 64Cu-Labeled AbegrinTM, a Humanized Monoclonal Antibody against Integrin αvβ3

W. Cai, Xiaoyuan Chen, Qizhen Cao, 2006 .

Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy.

W. Cai, V. Tse, Xiaoyuan Chen, 2007, Recent patents on anti-cancer drug discovery.

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice.

Robert Sinclair, Sanjiv S Gambhir, Shimon Weiss, 2008, Small.

Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel.

Kai Chen, Weibo Cai, Victor Tse, 2007, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation.

J. Bading, P. Conti, Xiaoyuan Chen, 2004, Nuclear medicine and biology.

Development of individualized anti-metastasis strategies by engineering nanomedicines.

Z. Qian, Xiaoyuan Chen, Qi-Zhen He, 2015, Chemical Society reviews.

A thiol-reactive 18F-labeling agent, N-[2-(4-18F-fluorobenzamido)ethyl]maleimide, and synthesis of RGD peptide-based tracer for PET imaging of alpha v beta 3 integrin expression.

Weibo Cai, Xianzhong Zhang, W. Cai, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Treatment of cystic craniopharyngioma with phosphorus-32 intracavitary irradiation

Xiaoyuan Chen, X. Liang, J. Wang, 2010, Child's Nervous System.

Small-Animal PET of Melanocortin 1 Receptor Expression Using a 18F-Labeled α-Melanocyte-Stimulating Hormone Analog

S. Gambhir, E. Graves, Xiaoyuan Chen, 2007, Journal of Nuclear Medicine.

Noninvasive imaging of tumor integrin expression using 18F-labeled RGD dimer peptide with PEG4 linkers

Fan Wang, Shuanglong Liu, Xiaoyuan Chen, 2009, European Journal of Nuclear Medicine and Molecular Imaging.

Integrin Targeted Delivery of Chemotherapeutics

Xiaoyuan Chen, Xiaoyuan Chen, Kai Chen, 2011, Theranostics.

Integrin Targeted Delivery of Radiotherapeutics

Xiaoyuan Chen, Fan Wang, Zhaofei Liu, 2011, Theranostics.

Evaluation of a 99mTc-Labeled Cyclic RGD Tetramer for Noninvasive Imaging Integrin αvβ3-Positive Breast Cancer

Young-Seung Kim, Wen-Yuan Hsieh, Bing Jia, 2007 .

18F-Labeled Galacto and PEGylated RGD Dimers for PET Imaging of αvβ3 Integrin Expression

Kai Chen, Frederick T. Chin, Hans-Jürgen Wester, 2010, Molecular Imaging and Biology.

Pegylated Arg-Gly-Asp Peptide: 64Cu Labeling and PET Imaging of Brain Tumor αvβ3-Integrin Expression

Peter S. Conti, Ryan Park, Michel Tohme, 2004 .

Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.

J. Bading, P. Conti, Xiaoyuan Chen, 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In Vivo Bioluminescence Tumor Imaging of RGD Peptide-modified Adenoviral Vector Encoding Firefly Luciferase Reporter Gene

S. Gambhir, W. Cai, Xiaoyuan Chen, 2007, Molecular Imaging and Biology.

Positron emission tomography imaging using radiolabeled inorganic nanomaterials.

Weibo Cai, Xiaolian Sun, W. Cai, 2015, Accounts of chemical research.

Multimodality Molecular Imaging of Tumor Angiogenesis

Weibo Cai, W. Cai, Xiaoyuan Chen, 2008, Journal of Nuclear Medicine.

Nanoplatforms for targeted molecular imaging in living subjects.

Weibo Cai, W. Cai, Xiaoyuan Chen, 2007, Small.

Improving tumor uptake and excretion kinetics of 99mTc-labeled cyclic arginine-glycine-aspartic (RGD) dimers with triglycine linkers.

Young-Seung Kim, Jiyun Shi, Xiaoyuan Chen, 2008, Journal of medicinal chemistry.

A new PET tracer specific for vascular endothelial growth factor receptor 2

Amir Kashefi, Kai Chen, Weibo Cai, 2007, European Journal of Nuclear Medicine and Molecular Imaging.

RGD-Cy7 Conjugates as Near-Infrared Fluorescence Probes to Image αvβ3 Integrin Expression in Brain Tumor Xenografts

Xiaoyuan Chen, Yun Wu, 2006 .

MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides.

Ryan Park, Michel Tohme, J. Bading, 2004, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Anti-Angiogenic Cancer Therapy Based on Integrin αvβ3 Antagonism

Weibo Cai, W. Cai, Xiaoyuan Chen, 2006 .

Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects.

Sanjiv S Gambhir, Kai Chen, Weibo Cai, 2006, Nano letters.

InAs/InP/ZnSe core/shell/shell quantum dots as near-infrared emitters: Bright, narrow-band, non-cadmium containing, and biocompatible

Kai Chen, Xiaogang Peng, Xiaoyuan Chen, 2008, Nano research.

Integrin αvβ3-Targeted Radioimmunotherapy of Glioblastoma Multiforme

Fan Wang, Kai Chen, Bing Jia, 2008, Clinical Cancer Research.

The temporal correlation of dynamic contrast-enhanced magnetic resonance imaging with tumor angiogenesis in a murine glioblastoma model

W. Cai, V. Tse, Xiaoyuan Chen, 2008, Neurological research.

Integrin αβ3-Targeted Imaging of Lung Cancer

J. Bading, P. Conti, Xiaoyuan Chen, 2005 .

Specific Targeting of Human Integrin α v β 3 with 111 In-Labeled Abegrin™ in Nude

Xiaoyuan Chen, Zhaofei Liu, Hui-yun Zhao, 2011 .

Specific Targeting of Human Integrin αvβ3 with 111In-Labeled Abegrin™ in Nude Mouse Models

Fan Wang, Bing Jia, Huiyun Zhao, 2011, Molecular Imaging and Biology.

Advances in Anatomic, Functional, and Molecular Imaging of Angiogenesis

Xiaoyuan Chen, A. Hsu, Xiaoyuan Chen, 2008, Journal of Nuclear Medicine.

microPET Imaging of Glioma Integrin αvβ3 Expression Using 64Cu-Labeled Tetrameric RGD Peptide

S. Gambhir, Xiaoyuan Chen, Zhen Cheng, 2005 .

Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide.

Ryan Park, Michel Tohme, J. Bading, 2004, Molecular imaging.

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis.

Rex Moats, Ryan Park, Michel Tohme, 2004, Nuclear medicine and biology.

Dual-Function Probe for PET and Near-Infrared Fluorescence Imaging of Tumor Vasculature

Sanjiv S. Gambhir, Kai Chen, Weibo Cai, 2007, Journal of Nuclear Medicine.

Are quantum dots ready for in vivo imaging in human subjects?

Weibo Cai, W. Cai, Xiaoyuan Chen, 2007, Nanoscale research letters.

Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma.

Xianzhong Zhang, Xiaoyuan Chen, Xianzhong Zhang, 2006, Nuclear medicine and biology.

Affibody-based nanoprobes for HER2-expressing cell and tumor imaging.

S. Gambhir, Xiaoyuan Chen, Zhen Cheng, 2011, Biomaterials.

Imaging of VEGF Receptor in a Rat Myocardial Infarction Model Using PET

J. Willmann, S. Gambhir, I. Y. Chen, 2008, Journal of Nuclear Medicine.

Molecular Imaging US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice 1

J. Willmann, S. Gambhir, I. Y. Chen, 2008 .

Pilot pharmacokinetic and dosimetric studies of (18)F-FPPRGD2: a PET radiopharmaceutical agent for imaging α(v)β(3) integrin levels.

Rhona A. Berganos, E. Mittra, A. Iagaru, 2011, Radiology.

Near-infrared quantum dots as optical probes for tumor imaging.

Xiaoyuan Chen, Zhen Cheng, Jinhao Gao, 2010, Current topics in medicinal chemistry.

Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots

Kai Chen, Weibo Cai, W. Cai, 2008, European Journal of Nuclear Medicine and Molecular Imaging.

Multimodality tumor imaging targeting integrin α v β 3

Weibo Cai, Sanjiv Sam Gambhir, S. Gambhir, 2005 .

Preparation and characterization of 99mTc(CO)3–BPy–RGD complex as αvβ3 integrin receptor-targeted imaging agent

Xiaoyuan Chen, Xianzhong Zhang, Xiaoyuan Chen, 2007 .

Synthesis of (4-[18F]fluorophenyl)triphenylphosphonium as a potential imaging agent for mitochondrial dysfunction

Sanjiv S. Gambhir, Zhen Cheng, S. Gambhir, 2005 .

Firefly Luciferase–Based Dynamic Bioluminescence Imaging: A Noninvasive Technique to Assess Tumor Angiogenesis

V. Tse, Xiaoyuan Chen, M. Kalani, 2010, Neurosurgery.

64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics.

Xiaoyuan Chen, Zibo Li, M. Fan, 2008, Bioconjugate chemistry.

18F-Labeled BBN-RGD Heterodimer for Prostate Cancer Imaging

Eun Kyoung Ryu, Kai Chen, Xiaoyuan Chen, 2008, Journal of Nuclear Medicine.

18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer.

Eduard Schreibmann, Weibo Cai, Xianzhong Zhang, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBN.

Fan Wang, Xiaoyuan Chen, F. Chin, 2009, Journal of medicinal chemistry.

Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression.

Xiaoyuan Chen, Zibo Li, F. Chin, 2007, Bioconjugate chemistry.

Evaluation of a (99m)Tc-labeled cyclic RGD tetramer for noninvasive imaging integrin alpha(v)beta3-positive breast cancer.

Xiaoyuan Chen, Fan Wang, Shuang Liu, 2007, Bioconjugate chemistry.

Near-infrared fluorescent RGD peptides for optical imaging of integrin alphavbeta3 expression in living mice.

Zhen Cheng, Sanjiv Sam Gambhir, S. Gambhir, 2005, Bioconjugate chemistry.

(99m)technetium-HYNIC(tricine/TPPTS)-Aca-bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model.

Xiaoyuan Chen, R. Dierckx, P. Elsinga, 2011, Molecular pharmaceutics.

Combination of integrin siRNA and irradiation for breast cancer therapy.

Tianfang Li, Yong Yang, W. Cai, 2006, Biochemical and biophysical research communications.

Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.

Kai Chen, Weibo Cai, W. Cai, 2009, Cancer research.

Evaluation of 99 mTcN-MPO as a New Myocardial Perfusion Imaging Agent in Normal Dogs and in an Acute Myocardial Infarction Canine Model: Comparison with 99 mTc-Sestamibi

L. Bu, Xiaoyuan Chen, B. Shen, 2011, Molecular Imaging and Biology.

RGD-Human Serum Albumin Conjugates as Efficient Tumor Targeting Probes

Xiaoyuan Chen, Kai Chen, Jin Xie, 2009, Molecular imaging.

Semiconductor quantum dots for in vivo imaging.

Weibo Cai, W. Cai, Xiaoyuan Chen, 2007, Journal of nanoscience and nanotechnology.

PET imaging of tumor integrin expression

Xiaoyuan Chen, Weibo Cai, W. Cai, 2005, 2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05).

MicroPET, MicroSPECT, and NIR fluorescence imaging of biomolecules in vivo.

Xiaoyuan Chen, Zibo Li, 2009, Methods in molecular biology.

Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.

R. Dayam, N. Neamati, J. Deng, 2006, Journal of medicinal chemistry.

DCE-MRI-Derived Parameters in Evaluating Abraxane-Induced Early Vascular Response and the Effectiveness of Its Synergistic Interaction with Cisplatin

Xiaoyuan Chen, B. Shen, Kai Wang, 2016, PloS one.

Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes.

S. Gambhir, H. Dai, S. Gambhir, 2008, Nano letters.

Molecular Imaging Probes for Cancer Research

Xiaoyuan Chen, 2012 .

Molecular imaging can accelerate anti-angiogenic drug development and testing

Andrei Iagaru, Sanjiv Sam Gambhir, A. Iagaru, 2007, Nature Clinical Practice Oncology.

Development of individualized anti-metastasis strategies by engineering nanomedicines.

Z. Qian, Xiaoyuan Chen, Qi-Zhen He, 2015, Chemical Society reviews.

Pilot pharmacokinetic and dosimetric studies of (18)F-FPPRGD2: a PET radiopharmaceutical agent for imaging α(v)β(3) integrin levels.

Rhona A. Berganos, E. Mittra, A. Iagaru, 2011, Radiology.

Monitoring of the Biological Response to Murine Hindlimb Ischemia With 64Cu-Labeled Vascular Endothelial Growth Factor-121 Positron Emission Tomography

J. Willmann, S. Gambhir, I. Y. Chen, 2008, Circulation.

Integrin avB3–Targeted Imaging of Lung Cancer

J. Bading, P. Conti, Xiaoyuan Chen, 2005 .

PET/MRI Dual-Modality Tumor Imaging Using Arginine-Glycine-Aspartic (RGD)–Conjugated Radiolabeled Iron Oxide Nanoparticles

Chenjie Xu, Xiaoyuan Chen, Shouheng Sun, 2008, Journal of Nuclear Medicine.

Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBN.

Xiaoyuan Chen, F. Chin, Zhaofei Liu, 2009, Journal of medicinal chemistry.

64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria.

Xiaoyuan Chen, Yang Zhou, Orit Jacobson, 2011, Molecular pharmaceutics.

(18)F, (64)Cu, and (68)Ga labeled RGD-bombesin heterodimeric peptides for PET imaging of breast cancer.

Xiaoyuan Chen, Zhaofei Liu, Shuanglong Liu, 2009, Bioconjugate chemistry.

Integrin alpha v beta 3 antagonists for anti-angiogenic cancer treatment.

W. Cai, V. Tse, Xiaoyuan Chen, 2007, Recent patents on anti-cancer drug discovery.