I. Pandrea

C. Apetrei, I. Pandrea, K. Raehtz, 2016, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

G. Learn, H. Liao, J. Sodroski, 2016, Proceedings of the National Academy of Sciences.

Analysis of partial pol and env sequences indicates a high prevalence of HIV type 1 recombinant strains circulating in Gabon.

D. Robertson, P. Roques, C. Apetrei, 2002, AIDS research and human retroviruses.

Genetic Identity and Biological Phenotype of a Transmitted/Founder Virus Representative of Nonpathogenic Simian Immunodeficiency Virus Infection in African Green Monkeys

G. Learn, F. Kirchhoff, N. Parrish, 2010, Journal of Virology.

Effect of B-Cell Depletion on Viral Replication and Clinical Outcome of Simian Immunodeficiency Virus Infection in a Natural Host

D. Montefiori, R. Ribeiro, C. Apetrei, 2009, Journal of Virology.

Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain.

David Montefiori, Amitinder Kaur, D. Montefiori, 2009, Blood.

Paucity of CD4 (cid:1) CCR5 (cid:1) T cells is a typical feature of natural SIV hosts

Ronald S Veazey, Amitinder Kaur, Guido Silvestri, 2022 .

Simian Immunodeficiency Virus SIVagm.sab Infection of Caribbean African Green Monkeys: a New Model for the Study of SIV Pathogenesis in Natural Hosts

F. Barré-Sinoussi, A. Lackner, C. Apetrei, 2006, Journal of Virology.

High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx.

L. White, P. Roques, C. Apetrei, 2003, Virology.

Simian Immunodeficiency Virus SIVagm Dynamics in African Green Monkeys

A. Perelson, R. Ribeiro, C. Apetrei, 2008, Journal of Virology.

Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research

J. Mellors, C. Apetrei, I. Pandrea, 2015, Journal of Virology.

In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques.

C. Apetrei, I. Pandrea, P. Marx, 2007, Virology.

Running head: Paucity of viral target cells in natural SIV hosts

A. Lackner, P. Roques, C. Apetrei, 2013 .

Changes to the Simian Immunodeficiency Virus (SIV) Reservoir and Enhanced SIV-Specific Responses in a Rhesus Macaque Model of Functional Cure after Serial Rounds of Romidepsin Administrations

C. Apetrei, I. Pandrea, Q. Le Hingrat, 2022, Journal of virology.

Experimental depletion of CD8+ cells in acutely SIVagm-Infected African Green Monkeys results in increased viral replication

R. Ribeiro, C. Apetrei, I. Pandrea, 2010, Retrovirology.

Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

J. Brenchley, C. Apetrei, I. Pandrea, 2023, Nature Communications.

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure

B. Haynes, J. Lifson, G. Shaw, 2021, bioRxiv.

Mucosal immune dysfunction in AIDS pathogenesis.

C. Apetrei, I. Pandrea, I. Frank, 2008, AIDS reviews.

CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections

B. Hahn, C. Apetrei, I. Pandrea, 2016, Journal of Virology.

Simian Immunodeficiency Virus: Natural Infection

C. Apetrei, I. Pandrea, G. Silvestri, 2008 .

Kuru experiments triggered the emergence of pathogenic SIVmac.

D. Robertson, A. Lackner, C. Apetrei, 2006, AIDS.

Molecular Epidemiology of Simian Immunodeficiency Virus SIVsm in U.S. Primate Centers Unravels the Origin of SIVmac and SIVstm

D. Robertson, S. Staprans, H. McClure, 2005, Journal of Virology.

Using the Pathogenic and Nonpathogenic Nonhuman Primate Model for Studying Non-AIDS Comorbidities

C. Apetrei, I. Pandrea, R. Tracy, 2015, Current HIV/AIDS Reports.

Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication.

R. Ribeiro, C. Apetrei, I. Pandrea, 2014, The Journal of clinical investigation.

CD4-Like Immunological Function by CD4− T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus

Brigitte E. Sanders-Beer, J. Brenchley, C. Apetrei, 2011, Journal of Virology.

Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction.

J. Brenchley, C. Apetrei, I. Pandrea, 2010, The Journal of infectious diseases.

Severe Depletion of Mucosal CD4+ T Cells in AIDS-Free Simian Immunodeficiency Virus-Infected Sooty Mangabeys1

S. Staprans, D. Douek, J. Brenchley, 2007, The Journal of Immunology.

Comparison of Simian Immunodeficiency Virus SIVagmVer Replication and CD4+ T-Cell Dynamics in Vervet and Sabaeus African Green Monkeys

J. Schmitz, I. Pandrea, Charles R. Brown, 2006, Journal of Virology.

Immunovirological Analyses of Chronically Simian Immunodeficiency Virus SIVmnd-1- and SIVmnd-2-Infected Mandrills (Mandrillus sphinx)

R. Ribeiro, P. Roques, C. Apetrei, 2011, Journal of Virology.

Immunovirological Analyses of Chronically Simian Immunodeficiency Virus SIVmnd-1- and SIVmnd-2-Infected Mandrills (Mandrillus sphinx)

R. Ribeiro, P. Roques, C. Apetrei, 2011, Journal of Virology.

Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction

D. Montefiori, C. Apetrei, I. Pandrea, 2017, Journal of Virology.

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention, and Cure

B. Haynes, J. Lifson, G. Shaw, 2021, Journal of Virology.

Modeling aging in HIV infection in nonhuman primates to address an emerging challenge of the post-ART era.

I. Pandrea, E. Brocca-Cofano, Tianyu He, 2017, Current opinion in virology.

Tetravalent SARS-CoV-2 S1 Subunit Protein Vaccination Elicits Robust Humoral and Cellular Immune Responses in SIV-Infected Rhesus Macaque Controllers

F. Baldanti, A. Gambotto, C. Apetrei, 2023, bioRxiv.

Transient early post‐inoculation anti‐retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut‐associated lymphoid tissues in SIVmac239‐infected rhesus macaques, but not resistance to rechallenge

J. Blanchard, J. Lifson, M. Piatak, 2003, Journal of medical primatology.

The dynamics of SIV 2-LTR Circles in the Presence and Absence of CD8+ Cells

R. Ribeiro, C. Apetrei, I. Pandrea, 2018 .

Simian Immunodeficiency Virus SIVrcm, a Unique CCR2-Tropic Virus, Selectively Depletes Memory CD4+ T Cells in Pigtailed Macaques through Expanded Coreceptor Usage In Vivo

C. Apetrei, I. Pandrea, P. Marx, 2009, Journal of Virology.

SIVrcm , a unique CCR 2-tropic virus , selectively 2 depletes memory CD 4 + T cells in pigtailed macaques through expanded coreceptor usage in vivo 4 Running Title : Pathogenesis of SIVrcm infection in PTMs 6-- -8

C. Apetrei, I. Pandrea, P. Marx, 2009 .

Mucosal Innate Immune Response Associated with a Timely Humoral Immune Response and Slower Disease Progression after Oral Transmission of Simian Immunodeficiency Virus to Rhesus Macaques

I. Pandrea, D. Sodora, J. Milush, 2007, Journal of Virology.

Resistance of the human colon carcinoma cell line HCT‐8 to methotrexate results in selection of cells with features of enterocytic differentiation

A. Barbat, I. Pandrea, T. Lesuffleur, 1998, International journal of cancer.

Cutting Edge: T Regulatory Cell Depletion Reactivates Latent Simian Immunodeficiency Virus (SIV) in Controller Macaques While Boosting SIV-Specific T Lymphocytes

C. Apetrei, I. Pandrea, R. Sivanandham, 2016, The Journal of Immunology.

Nonhuman Primate Models for HIV Cure Research

J. Mellors, C. Apetrei, I. Pandrea, 2012, PLoS pathogens.

Use of a Small Molecule CCR5 Inhibitor in Macaques to Treat Simian Immunodeficiency Virus Infection or Prevent Simian–Human Immunodeficiency Virus Infection

R. Doms, John P. Moore, Steven Wolinsky, 2003, The Journal of experimental medicine.

ANTIRETROVIRAL THERAPY IN ROMANIA : HAART ?

F. Brun-Vézinet, C. Apetrei, I. Pandrea, 2008 .

Chronic SIV infection ultimately causes immunodeficiency in African non-human primates.

P. Roques, C. Apetrei, I. Pandrea, 2001, AIDS.

Population Bottlenecks and Pathogen Extinction: “Make This Everyone's Mission to Mars, Including Yours”

C. Apetrei, I. Pandrea, B. Policicchio, 2015, Journal of Virology.

Pattern of SIVagm Infection in Patas Monkeys Suggests that Host Adaptation to SIV Infection May Result in Resistance to Infection and Virus Extinction

J. Brenchley, C. Apetrei, I. Pandrea, 2010 .

T cell activation is insufficient to drive SIV disease progression

R. Ribeiro, A. Lackner, C. Apetrei, 2023, JCI insight.

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers

J. Mellors, G. Shaw, R. Ribeiro, 2016, PLoS pathogens.

The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.

Judith N. Mandl, S. Staprans, M. Feinberg, 2006 .

Functional Cure of SIVagm Infection in Rhesus Macaques Results in Complete Recovery of CD4+ T Cells and Is Reverted by CD8+ Cell Depletion

D. Montefiori, R. Ribeiro, B. Keele, 2011, PLoS pathogens.

CD 4-Like Immunological Function by CD 4 T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus †

Brigitte E. Sanders-Beer, J. Brenchley, C. Apetrei, 2011 .

Down-regulation of CD4 by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

J. Brenchley, C. Apetrei, I. Pandrea, 2009, Nature Medicine.

HIV type 1 genetic diversity and genotypic drug susceptibility in the Republic of Moldova.

D. Robertson, C. Apetrei, I. Pandrea, 2001, AIDS research and human retroviruses.

Immunovirological Analyses of Chronically Simian Immunodeficiency Virus SIVmnd-1- and SIVmnd-2-Infected Mandrills (Mandrillus sphinx)

R. Ribeiro, P. Roques, C. Apetrei, 2011, Journal of Virology.

Paucity of CD4+ CCR5+ T Cells May Prevent Transmission of Simian Immunodeficiency Virus in Natural Nonhuman Primate Hosts by Breast-Feeding

P. Roques, C. Apetrei, I. Pandrea, 2008, Journal of Virology.

Simian immunodeficiency virus types 1 and 2 (SIV mnd 1 and 2) have different pathogenic potentials in rhesus macaques upon experimental cross-species transmission.

P. Roques, C. Apetrei, I. Pandrea, 2009, The Journal of general virology.

Distinct expression profiles of TGF-β1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections

F. Barré-Sinoussi, I. Pandrea, M. Müller-Trutwin, 2006, Retrovirology.

CD8+ T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production

A. Perelson, E. F. Cardozo-Ojeda, R. Ribeiro, 2023, Nature Communications.

Making a Monkey out of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Pathogenesis: Immune Cell Depletion Experiments as a Tool to Understand the Immune Correlates of Protection and Pathogenicity in HIV Infection

C. Apetrei, I. Pandrea, K. Raehtz, 2024, Viruses.