D. Williams

发表

Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine.

M. Lamers, A. Antson, R. Hubbard, 1999, Journal of molecular biology.

An enthalpic component in cooperativity: the relationship between enthalpy, entropy, and noncovalent structure in weak associations.

D. Williams, C. Calderone, C T Calderone, 2001, Journal of the American Chemical Society.

A vesicle capture sensor chip for kinetic analysis of interactions with membrane-bound receptors.

Dudley H. Williams, A. Hansson, D. Williams, 2000, Analytical biochemistry.

On the stability of nucleic acid structures in solution: enthalpy-entropy compensations, internal rotations and reversibility.

Dudley H. Williams, D. Williams, M. Searle, 1993, Nucleic acids research.

Recent kinase and kinase inhibitor X-ray structures: mechanisms of inhibition and selectivity insights.

D. Williams, M. Cherry, 2004, Current medicinal chemistry.

Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics.

Dudley H. Williams, U. Gerhard, J. Mackay, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry.

B. Gibson, D. Williams, C. Holmes, 1988, European journal of biochemistry.

Molecular basis for methoxyamine initiated mutagenesis. 1H nuclear magnetic resonance studies of base-modified oligodeoxynucleotides.

D. M. Brown, D. Williams, M. Stone, 1991, Journal of molecular biology.

A mass-spectrometric sequence study of the enzyme ribitol dehydrogenase from Klebsiella aerogenes.

D. Williams, H. Morris, B. Hartley, 1974, The Biochemical journal.

Surface plasmon resonance analysis at a supported lipid monolayer.

D. Williams, M. Cooper, D. Ellar, 1998, Biochimica et biophysica acta.

Incorporation of fluorotryptophan into triostin antibiotics by Streptomyces triostinicus.

M. Waring, D. Williams, K. Fox, 1985, Journal of general microbiology.

Configuration assignments of the amino acid residues and the presence of N-methyldehydroalanine in toxins from the blue-green alga, Microcystis aeruginosa.

D. Williams, P. Wessels, D. Botes, 1982, Toxicon : official journal of the International Society on Toxinology.

Formaldehyde adducts of glutathione. Structure elucidation by two-dimensional n.m.r. spectroscopy and fast-atom-bombardment tandem mass spectrometry.

R. Mason, D. Williams, J. Sanders, 1988, The Biochemical journal.

Fast-atom-bombardment mass spectrometry. A new technique for the determination of molecular weights and amino acid sequences of peptides.

D. Williams, G. Bojesen, S. Santikarn, 1982, The Biochemical journal.

Analysis of N-acetylated hexosamine monosaccharides by ferrocenyl boronation and tandem electrospray ionization mass spectrometry.

D. Williams, M. Young, N. Dinh, 2000, Rapid communications in mass spectrometry : RCM.

Analysis of neutral isomeric low molecular weight carbohydrates using ferrocenyl boronate derivatization and tandem electrospray mass spectrometry.

D. Williams, M. Young, 2000, Rapid communications in mass spectrometry : RCM.

Structural elucidation of N-terminal post-translational modifications by mass spectrometry: application to chicken enolase and the alpha- and beta-subunits of bovine mitochondrial F1-ATPase.

B. Gibson, D. Williams, D. Daley, 1988, Analytical biochemistry.

Studies towards the complete sequence determination of proteins by mass spectrometry: derivatisation of methionine, cysteine and arginine containing peptides.

Dudley H. Williams, D. Williams, H. Morris, 1973, Biochemical and biophysical research communications.

The determination of sequence information in homologously related proteins by mass spectrometry.

D. Williams, A. Dell, H. Morris, 1974, Biomedical mass spectrometry.

Identification of highly acidic peptides from processing of the skin prepropeptides of Xenopus laevis.

D. Williams, J. Nutkins, 1989, European journal of biochemistry.

Ratiometric analysis of the ferrocene boronate esters of 2- and 4-hydroxyestradiol by tandem electrospray mass spectrometry.

D. Williams, M. Young, S. Chen, 2001, Rapid communications in mass spectrometry : RCM.

The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide.

C. H. Moore, B. Gibson, M. Giovannini, 1988, The Journal of biological chemistry.

Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences.

C. H. Moore, B. Gibson, M. Giovannini, 1988, The Journal of biological chemistry.

Identification of the C-terminus of rabbit skeletal muscle glycogen synthase.

P. Cohen, B. Gibson, D. Williams, 1986, Biochemical and biophysical research communications.

Aurothioglucose inhibits induced NF-kB and AP-1 activity by acting as an IL-1 functional antagonist.

D. Williams, E. Murray, L. Jeffery, 1992, Biochimica et biophysica acta.

Amino acid sequence at the site on protein phosphatase inhibitor-2, phosphorylated by glycogen synthase kinase-3.

P. Cohen, D. Williams, A. Aitken, 1984, Biochimica et biophysica acta.

Protein kinase C is not a downstream effector of p21ras in activated T cells

D. Williams, D. Cantrell, M. Woodrow, 1995, European journal of immunology.

Kinetic analysis of high-mobility-group proteins HMG-1 and HMG-I/Y binding to cholesterol-tagged DNA on a supported lipid monolayer.

D. Williams, J. Gray, M. Cooper, 2000, Nucleic acids research.

19F NMR in the measurement of binding affinities of chloroeremomycin to model bacterial cell-wall surfaces that mimic VanA and VanB resistance.

D. Williams, D. O'Brien, M. Cooper, 1998, Chemistry & biology.

Semiquantitation of cooperativity in binding of vancomycin-group antibiotics to vancomycin-susceptible and -resistant organisms

D. Williams, D. Beauregard, P. Reynolds, 1997, Antimicrobial agents and chemotherapy.

Dimerization and membrane anchors in extracellular targeting of vancomycin group antibiotics

Dudley H. Williams, D. Williams, D. Beauregard, 1995, Antimicrobial agents and chemotherapy.

Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones.

B. Gibson, M. Giovannini, D. Williams, 1987, The Biochemical journal.

Molecular basis of the activity of antibiotics of the vancomycin group

D. Williams, J. Waltho, 1989, Biochemical pharmacology.

Why are secondary metabolites (natural products) biosynthesized?

D. Williams, M. Stone, S. K. Rahman, 1989, Journal of natural products.

Proton nuclear Overhauser effect study of the structure of a deoxyoligonucleotide duplex in aqueous solution.

Z. Shakked, D. Williams, D. Reid, 1983, Biochemistry.

Bacillus thuringiensis Cry1Ac toxin interaction with Manduca sexta aminopeptidase N in a model membrane environment.

E. Travis, D. Williams, M. Cooper, 1998, The Biochemical journal.

Human MAFA has alternatively spliced variants.

M. Lamers, D. Williams, A. Lamont, 1998, Biochimica et biophysica acta.

Structural elucidation of XR586, a peptaibol-like antibiotic from Acremonium persicinum.

D. Williams, S. Wrigley, T. Gibson, 1996, The Biochemical journal.

Novel peptide fragments originating from PGLa and the caerulein and xenopsin precursors from Xenopus laevis.

B. Gibson, D. Williams, J. Maggio, 1986, The Journal of biological chemistry.

Synthesis of 24xi, 25-dihydroxyprovitamin D3.

D. Williams, S. Eyley, 1976, Journal of the Chemical Society. Perkin transactions 1.

Synthesis of 25-hydroxyprovitamin D3 and 25xi, 26-dihydroxyprovitamin D3.

D. Williams, S. Eyley, 1976, Journal of the Chemical Society. Perkin transactions 1.

The NMR spectra of four-membered carbocyclic ring systems

I. Fleming, D. Williams, 1967 .

Thermostability of Bacillus cereus Penicillinase

D. Williams, A. Bondi, A. G. Moat, 1966, Journal of bacteriology.

Hydrophobic interactions affect hydrogen bond strengths in complexes between peptides and vancomycin or ristocetin.

D. Williams, M. Williamson, 1984, European journal of biochemistry.

D. Williams, E. Houghton, C. Bradley, 1983, Biomedical mass spectrometry.

Characterization of novel antibiotics of the triostin group by fast atom bombardment mass spectrometry.

M. Waring, D. Williams, A. Cornish, 1983, The Journal of antibiotics.

Stereochemistry of naturally-occurring 25-hydroxyvitamin D3-26,23 lactone as determined by radioligand binding analysis and high-performance liquid chromatography.

D. Williams, R. Horst, T. Reinhardt, 1982, Biochemical and biophysical research communications.

Left handed alpha-helix formation by a bacterial peptide.

R. Mortishire-Smith, D. Williams, A. Drake, 1991, FEBS letters.

Use of inter-proton nuclear Overhauser effects to assign the nuclear magnetic resonance spectra of oligodeoxynucleotide and hybrid duplexes in aqueous solution.

D. Williams, T. Brown, B. Rayner, 1983, European journal of biochemistry.

Studies in mass spectrometry—XVIII

G. Schroll, D. Williams, J. Bowie, 1967 .

Structure revision of the antibiotic echinomycin.

D. Williams, A. Dell, H. Morris, 1975, Journal of the American Chemical Society.

Study of ‘difficult peptides’ from Paracoccus cytochrome c‐550 and a dolphin cytochrome c

Dudley H. Williams, D. Williams, A. Auffret, 1981, FEBS letters.

Binding of glycopeptide antibiotics to a model of a vancomycin-resistant bacterium.

D. Williams, M. Cooper, M A Cooper, 1999, Chemistry & biology.

The structure and mode of action of glycopeptide antibiotics of the vancomycin group.

D. Williams, J. Barna, D H Williams, 1984, Annual review of microbiology.

Antibiotics of the ostreogrycin complex. Part II. Structure of ostreogrycin A

D. Williams, D. Kingston, P. S. Sarin, 1966 .

Antibiotics of the ostreogrycin complex. 3. The structure of ostreogrycin A. Evidence based on nuclear magnetic double resonance experiments and high-resolution mass spectrometry.

D. Williams, D. Kingston, L. Todd, 1966, Journal of the Chemical Society. Perkin transactions 1.

The structure of ostreogrycin A.

D. Williams, D. Kingston, G. Delpierre, 1966, Tetrahedron letters.

Two conformers of the glycopeptide antibiotic teicoplanin with distinct ligand binding sites.

U. Gerhard, D. Williams, M. Westwell, 1995, The Journal of antibiotics.

The structure of an asymmetric dimer relevant to the mode of action of the glycopeptide antibiotics.

J. Mackay, D. Williams, M. Searle, 1994, Structure.

Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.

Steven J. M. Jones, Dudley H. Williams, S. Jones, 1998, Chemistry & biology.

Solvent effects in NMR spectroscopy. 3. Chemical shifts induced by benzene in ketones.

D. Williams, N. Bhacca, 1965, Tetrahedron.

Solvent effects in NMR spectroscopy—III

D. Williams, N. Bhacca, 1965 .

Molecular recognition by secondary metabolites.

R. Mortishire-Smith, D. Williams, M. Stone, 1990, Biochemical pharmacology.

The evolutionary role of secondary metabolites--a review.

Dudley H. Williams, D. Williams, M. Stone, 1992, Gene.

The reaction of triphenylphosphine with phenylacetylene

D. Williams, J. Tebby, D. Allen, 1965 .

Structural and mode of action studies on the antibiotic vancomycin. Evidence from 270-MHz proton magnetic resonance.

D. Williams, J. Kalman, 1977, Journal of the American Chemical Society.

Oligosaccharide profiling: the facile detection of mono-, di- and oligosaccharides by electrospray orthogonal time-of-flight mass spectrometry using 3-aminophenylboronic acid derivatization.

D. Williams, T. Lee, M. Young, 2000, Rapid communications in mass spectrometry : RCM.

Nuclear magnetic resonance shift reagents in organic chemistry

D. Williams, 1974 .

Mass spectrometry in structural and stereochemical problems. XLVI11For paper XLV see Beugelmans, R., Williams, D.H., Budzikiewicz, H., and Djerassi, C., J. AM. CHEM. SOC., submitted for publication. the mass spectrometric fragmentation of steroidal ethylene ketals and ethylene thioketals

C. Djerassi, D. Williams, H. Budzikiewicz, 1963 .

Studies in Mass Spectrometry. I. Mass Spectra of Substituted Naphthoquinones

D. Williams, J. Bowie, D. Cameron, 1965 .

Isolation and structure elucidation of ampicillin and amoxicillin oligomers

E. Roets, J. Hoogmartens, D. Williams, 1984 .

Effect of ranitidine on the pharmacokinetics of triazolam and α‐hydroxytriazolam in both young (19‐60 years) and older (61‐78 years) people

D. Williams, K. Kersey, K. Koch, 2001 .

Determination of the sequences of protein-derived peptides and peptide mixtures by mass spectrometry.

Dudley H. Williams, D. Williams, H. Morris, 1971, The Biochemical journal.

Studies in mass spectrometry—XVIII : The relative ease of loss of alkyl radicals from ethylene acetals and ketals upon electron impact

D. Williams, J. Marshall, 1967 .

Biosynthesis of the vancomycin group of antibiotics: characterisation of a type III polyketide synthase in the pathway to (S)-3,5-dihydroxyphenylglycine.

D. Williams, H. Hong, O. W. Choroba, 2001, Chemical communications.

Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

N. Borkakoti, F. Winkler, A. D'arcy, 1994, Nature Structural Biology.

SPIN-SPIN COUPLING BETWEEN HYDROGEN AND STEROID ANGULAR METHYL PROTONS.

D. Williams, N. Bhacca, J. E. Gurst, 1963, Journal of the American Chemical Society.

Studies in mass spectroscopy—II : Mass spectra of substituted furans

J. A. Knight, R. Grigg, D. Williams, 1965 .

Synthesis of tachysterol

D. Williams, R. Davidson, B. Lythgoe, 1963 .

Studies in mass spectrometry. Part VII. Mass spectra of thiazoles

R. Grigg, D. Williams, G. M. Clarke, 1966 .

Studies in mass spectrometry—XX : Bond-forming reactions occurring in the fragmentation of some α,β-unsaturated esters and nitriles upon electron impact

G. Schroll, D. Williams, R. Cooks, 1967 .

Studies in mass spectrometry—XV : Mass spectra of sulphoxides and sulphones. The formation of CC and CO bonds upon electron impact☆

G. Schroll, D. Williams, J. Bowie, 1966 .

Determination of the structure of exochelin MN, the extracellular siderophore from Mycobacterium neoaurum.

D. Williams, C. Ratledge, D. Ewing, 1995, Chemistry & biology.

Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp.

D. Williams, S. Wrigley, C. Mcnicholas, 2001, Journal of the American Chemical Society.

Binding of vancomycin group antibiotics to D-alanine and D-lactate presenting self-assembled monolayers.

C. Abell, D. Williams, M. Cooper, 2000, Bioorganic & medicinal chemistry.

An analysis of the origins of a cooperative binding energy of dimerization.

D. Williams, M. Westwell, W. Tsuzuki, 1998, Science.

Characterisation of a hydroxymandelate oxidase involved in the biosynthesis of two unusual amino acids occurring in the vancomycin group of antibiotics.

D. Williams, A. Sandercock, O. W. Choroba, 2001, Chemical communications.

Induction of asymmetry into homodimers.

D. Williams, B. Bardsley, M. Westwell, 1998, Chirality.

A limitation of two-state analysis for transitions between disordered and weakly ordered states.

D. Williams, B. Bardsley, W. Tsuzuki, 1997, Chemistry & biology.

Is the hydrophobic effect stabilizing or destabilizing in proteins? The contribution of disulphide bonds to protein stability.

A. Doig, D. Williams, A J Doig, 1991, Journal of molecular biology.

Cooperativity between non-polar and ionic forces in the binding of bacterial cell wall analogues by vancomycin in aqueous solution.

D. Williams, D. Beauregard, H. Yan, 1995, The Journal of antibiotics.

On the evolution of functional secondary metabolites (natural products)

D. Williams, M. Stone, 1992, Molecular microbiology.

Structural studies on the antibiotic vancomycin: Evidence for the presence of modified phenylglycine and beta-hydroxytyrosine units.

D. Williams, K. Smith, G. Smith, 1975, Journal of the Chemical Society. Perkin transactions 1.

The structure of an amino-sugar from the antibiotic vancomycin.

D. Williams, J. Feeney, J. P. Brown, 1972, Journal of the Chemical Society. Perkin transactions 1.

Structural studies on the antibiotic vancomycin; the nature of the aromatic rings.

D. Williams, K. Smith, G. Smith, 1974, Journal of the Chemical Society. Perkin transactions 1.

Substrate specificity and inhibitor profile of human recombinant p56lck from a baculovirus expression vector

D. Williams, H. Flotow, S. Wilkinson, 1996, Inflammation Research.

Baculoviral expression and characterization of rodent cathepsin S.

M. Lamers, D. Williams, C. Mason, 2001, Protein expression and purification.

Rapid determination of sequence variations in actinidin isolated from Actinidia chinensis (var. Hayward) using fast atom bombardment mapping mass spectrometry and gas phase microsequencing.

C. H. Moore, D. Williams, S. Naylor, 1989, Biomedical & environmental mass spectrometry.

Observations on the quantitation of the phosphate content of peptides by fast-atom bombardment mass spectrometry.

D. Williams, P. Cohen, L. Poulter, 1987, Biochimica et biophysica acta.

Why water-soluble, compact, globular proteins have similar specific enthalpies of unfolding at 110 degrees C.

A. Doig, D. Williams, 1992, Biochemistry.

Ro 09-2210 exhibits potent anti-proliferative effects on activated T cells by selectively blocking MKK activity.

D. Williams, H. Flotow, S. Wilkinson, 1998, Biochemistry.

Studies in mass spectrometry. Part V. Mass spectra of benzoquinones

D. Williams, J. Bowie, R. Giles, 1966 .

Characterization of Hb Aalborg, a new unstable hemoglobin variant, by fast atom bombardment mass spectrometry.

R. Carrell, D. Williams, S. Brennan, 1990, Hemoglobin.

Structure and conformation of fourteen antibiotics of the quinoxaline group determined by 1H NMR.

M. Waring, D. Williams, M. Williamson, 1982, Journal of antibiotics (Tokyo. 1968).

Isolation, purification and structure of exochelin MS, the extracellular siderophore from Mycobacterium smegmatis.

C Ratledge, D. Williams, C. Ratledge, 1995, The Biochemical journal.

Solvent effects in N.M.R. spectroscopy. I. Chemical shifts induced by benzene in some steroidal ketones and acetates

D. Williams, N. Bhacca, 1964 .

Studies in Mass Spectroscopy. III.1 Mass Spectra of β-Keto Esters

G. Schroll, D. Williams, J. Bowie, 1965 .

The formation of heterodimers by vancomycin group antibiotics.

A. Heck, P. Roepstorff, D. Williams, 2000, Chemistry.

Peptide sequencing using the combination of edman degradation, carboxypeptidase digestion and fast atom bombardment mass spectrometry.

D. Williams, M. Hanley, C. Bradley, 1982, Biochemical and biophysical research communications.

Structure elucidation of xanthone derivatives with CD4-binding activity from Penicillium glabrum (Wehmer) Westling

D. Williams, S. Wrigley, T. Gibson, 1994 .

Conformations of two duplex forms of d(TCGA) in slow-exchange equilibrium characterized by NMR.

D. Williams, T. Brown, D. Reid, 1985, Biochemistry.

Native-like beta-hairpin structure in an isolated fragment from ferredoxin: NMR and CD studies of solvent effects on the N-terminal 20 residues.

D. Williams, M. Searle, R. Zerella, 1996, Protein engineering.

Dissecting the structure of a partially folded protein. Circular dichroism and nuclear magnetic resonance studies of peptides from ubiquitin.

D N Woolfson, Dudley H. Williams, D. Woolfson, 1993, Journal of molecular biology.

STRATEGY FOR THE GENERATION OF CARBON-13 SUBSPECTRA. APPLICATION TO THE ANALYSIS OF THE CARBON-13 SPECTRUM OF THE ANTIBIOTIC RISTOCETIN

D. Doddrell, D. Williams, M. Bendall, 1982 .

Kinetic analysis of antibody-antigen interactions at a supported lipid monolayer.

D. Williams, M. Cooper, Mark E. Cooper, 1999, Analytical biochemistry.

Proton nuclear overhauser effect study of the structure of an actinomycin D complex with a self-complementary tetranucleoside triphosphate.

D. Williams, D. Reid, S. Salisbury, 1983, Biochemistry.

The influence of proline residues on alpha-helical structure.

D. Woolfson, D. Williams, 1990, FEBS letters.

Cooperativity and anti-cooperativity between ligand binding and the dimerization of ristocetin A: asymmetry of a homodimer complex and implications for signal transduction.

D. Williams, P. Groves, M. Westwell, 1996, Chemistry & biology.

Solvent shifts induced by benzene in triterpenes as an aid to structure elucidation

D. Williams, R. Wilson, 1969 .

Characterization of a partially denatured state of a protein by two-dimensional NMR: reduction of the hydrophobic interactions in ubiquitin.

Dudley H. Williams, D. Woolfson, D. Williams, 1991, Biochemistry.

Mass spectrometric sequence studies of a superoxide dismutase from Bacillus stearothermophilus.

D. Williams, A. Auffret, T. Blake, 1981, European journal of biochemistry.

A MODIFIED SYNTHESIS OF 1α-HYDROXYVITAMIN D3

D. Williams, D. W. Guest, 1979 .

Alkaloids of Daphnandra species. Part VIII. The structure of repanduline. The evidence based on mass spectrometry and nuclear magnetic resonance

D. Williams, J. Bowie, J. Harley-Mason, 1967 .

Why are secondary metabolites biosynthesized? Sophistication in the inhibition of cell wall biosynthesis by vancomycin group antibiotics.

D. Williams, R. Maplestone, 1992, Ciba Foundation symposium.

A 1H nOe and CD study of the salt-concentration dependence of the structure of d(G-C).

D. Williams, D. Reid, S. Salisbury, 1983, Nucleic acids research.

On the structure and mode of action of the antibiotic ristocetin A.

D. Williams, J. Kalman, V. Rajananda, 1979, Journal of the Chemical Society. Perkin transactions 1.

A mass spectrometric method for the identification of novel peptides in Xenopus laevis skin secretions.

B. Gibson, D. Williams, L. Poulter, 1986, Journal of natural products.

Conserved positioning of proline residues in membrane-spanning helices of ion-channel proteins.

R. Mortishire-Smith, D. Woolfson, D. Williams, 1991, Biochemical and biophysical research communications.

Enthalpy/entropy compensation as a competition between dynamics and bonding: the relevance to melting of crystals and biological aggregates.

D. Williams, D. O'Brien, B. Bardsley, 2001, Journal of the American Chemical Society.

Skeletal rearrangement reactions in sulphides, disulphides, sulphoxides and sulphones upon electron impact

G. Schroll, D. Williams, J. Bowie, 1965 .

Fast-atom-bombardment mass spectrometry. A new technique for the determination of molecular weights and amino acid sequences of peptides.

D. Williams, G. Bojesen, S. Santikarn, 1982, The Biochemical journal.

Calciferol and its relatives. Part IX. The synthesis of tachysterol3

D. Williams, R. Davidson, B. Lythgoe, 1967 .

Protein folding in the absence of the solvent ordering contribution to the hydrophobic interaction.

D. Woolfson, D. Williams, A. Cooper, 1993, Journal of molecular biology.

Weak interactions and lessons from crystallization.

D. Williams, M. Westwell, 1996, Chemistry & biology.