Dominik Handler

发表

The Rhino-Deadlock-Cutoff Complex Licenses Noncanonical Transcription of Dual-Strand piRNA Clusters in Drosophila

Fabio Mohn, Grzegorz Sienski, Dominik Handler, 2014, Cell.

Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.

Zhiping Weng, Julius Brennecke, Phillip D Zamore, 2015, Developmental cell.

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

D. Patel, K. Mechtler, Dominik Handler, 2019, bioRxiv.

Crystal structure of dmNxf2 NTF2-like domain in complex with Nxt1/p15

D. Patel, K. Mechtler, Dominik Handler, 2019 .

A genome-scale shRNA resource for transgenic RNAi in Drosophila

Norbert Perrimon, Julius Brennecke, Donghui Yang-Zhou, 2011, Nature Methods.

A universal method for the rapid isolation of all known classes of functional silencing small RNAs

Dominik Handler, J. Brennecke, O. Voinnet, 2020, Nucleic acids research.

piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis

Julius Brennecke, Fabio Mohn, Dominik Handler, 2015, Science.

The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters

Dominik Handler, J. Brennecke, P. Duchek, 2022, bioRxiv.

The evolution of an RNA-based memory of self in the face of genomic conflict

Dominik Handler, J. Brennecke, A. Burga, 2022, bioRxiv.

A systematic analysis of Drosophila TUDOR domain‐containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

R. Sachidanandam, A. Stark, K. Mechtler, 2011, The EMBO journal.

Genetic and mechanistic diversity of piRNA 3' end formation

Stefan L Ameres, Fabio Mohn, Dominik Handler, 2016, Nature.

The exon junction complex is required for definition and excision of neighboring introns in Drosophila

Dominik Handler, J. Brennecke, D. Ish-Horowicz, 2014, Genes & development.

The Genetic Makeup of the Drosophila piRNA Pathway

Dominik Handler, J. Brennecke, C. Schmied, 2013, Molecular cell.

Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq

Stefan L Ameres, P. Hufnagl, J. Peters, 2021, Nature Communications.

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

D. Patel, K. Mechtler, Dominik Handler, 2019, Nature Structural & Molecular Biology.

Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery

D. Patel, Grzegorz Sienski, Dominik Handler, 2022, Nature Structural & Molecular Biology.

A SUMO-dependent regulatory switch connects the piRNA pathway to the heterochromatin machinery in Drosophila

D. Patel, Grzegorz Sienski, Dominik Handler, 2021, bioRxiv.

Functional Adaptations of Endogenous Retroviruses to the Drosophila Host Underlie their Evolutionary Diversification

C. Kosiol, K. Senti, Dominik Handler, 2023, bioRxiv.

A conserved fertilization complex of Izumo1, Spaca6, and Tmem81 mediates sperm-egg interaction in vertebrates

Dominik Handler, M. Ikawa, A. Schleiffer, 2023, bioRxiv.

A genome-scale shRNA resource for transgenic RNAi in Drosophila

N. Perrimon, G. Hannon, Dominik Handler, 2011, Nature Methods.

Evolutionary adaptation of the chromodomain of the HP1-protein Rhino allows the integration of chromatin and DNA sequence signals

Dominik Handler, J. Brennecke, A. Schleiffer, 2023, bioRxiv.

Selfish conflict underlies RNA-mediated parent-of-origin effects

Dominik Handler, A. Burga, P. Duchek, 2024, Nature.

Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals

Dominik Handler, J. Brennecke, A. Schleiffer, 2024, bioRxiv.